Journal of Trace Elements in Medicine and Biology

Article	Citations
Vanadium: Risks and possible benefits in the light of a comprehensive overview of its pharmacotoxicological mechanisms and multi-applications with a summary of further research trends	134
Serum copper and zinc levels in breast cancer: A meta-analysis	87
Hexavalent chromium: Regulation and health effects	84
Metallobiology and therapeutic chelation of biometals (copper, zinc and iron) in Alzheimer’s disease: Limitations, and current and future perspectives	65
In-vitro evaluation of copper/copper oxide nanoparticles cytotoxicity and genotoxicity in normal and cancer lung cell lines	62
Comparative analysis of corrosion resistance between beta titanium and Ti-6Al-4V alloys: A systematic review	62
Environmental influence on neurodevelopmental disorders: Potential association of heavy metal exposure and autism	48
Colorectal cancer and trace elements alteration	48
Zinc and selenium supplementation in COVID-19 prevention and treatment: a systematic review of the experimental studies	47
Human biomonitoring of 73 elements in blood, serum, erythrocytes and urine	43
Absorption, distribution, metabolism and excretion (ADME) of oral selenium from organic and inorganic sources: A review	42
Low-level environmental lead and cadmium exposures and dyslipidemia in adults: Findings from the NHANES 2005–2016	41
Trace elements in children with autism spectrum disorder: A meta-analysis based on case-control studies	40
Role of ferroptosis in cisplatin-induced acute nephrotoxicity in mice	40
Assessment of copper, iron, zinc and manganese status and speciation in patients with Parkinson’s disease: A pilot study	38
Cyclophosphamide induced oxidative stress, lipid per oxidation, apoptosis and histopathological changes in rats: Protective role of boron	38
The impact of manganese on neurotransmitter systems	36
Pivotal role of boron supplementation on bone health: A narrative review	36
The sex-specific effects of blood lead, mercury, and cadmium levels on hepatic steatosis and fibrosis: Korean nationwide cross-sectional study	35
Vanadium as potential therapeutic agent for COVID-19: A focus on its antiviral, antiinflamatory, and antihyperglycemic effects	32
Revised D-A-CH-reference values for the intake of zinc	32
Glycine nano-selenium prevents brain oxidative stress and neurobehavioral abnormalities caused by MPTP in rats	32
Neurodevelopmental disorders: Metallomics studies for the identification of potential biomarkers associated to diagnosis and treatment	31
Does selenium fortification of kale and kohlrabi sprouts change significantly their biochemical and cytotoxic properties?	28
Tobacco smoke is a likely source of lead and cadmium in settled house dust	28

Characterizing effects of excess copper levels in a human astrocytic cell line with focus on oxidative stress markers	27
Blood cadmium levels as a marker for early lung cancer detection	27
High serum concentration of selenium, but not calcium, cobalt, copper, iron, and magnesium, increased the risk of both hyperglycemia and dyslipidemia in adults: A health examination center based cross	27
Cu isotope ratios are meaningful in ovarian cancer diagnosis	27
Global diversity of dietary intakes and standards for zinc, iron, and copper	26
Evaluating tissue levels of the eight trace elements and heavy metals among esophagus and gastric cancer patients: A comparison between cancerous and non-cancerous tissues	26
The effects of zinc supplementation on metabolic profile and oxidative stress in overweight/obese patients with non-alcoholic fatty liver disease: A randomized, double-blind, placebo-controlled trial	26
Bioelements in the treatment of burn injuries – The complex review of metabolism and supplementation (copper, selenium, zinc, iron, manganese, chromium and magnesium)	26
Toxicological impact of green synthesized silver nanoparticles and protective role of different selenium type on Oreochromis niloticus: hematological and biochemical response	26
Effect of ambient air PM2.5-bound heavy metals on blood metal(loid)s and children’s asthma and allergy pro-inflammatory (IgE, IL-4 and IL-13) biomarkers	25
Evaluation of zinc, copper, and Cu:Zn ratio in serum, and their implications in the course of COVID-19	25
Molecular mechanisms and therapeutic effects of different vitamins and minerals in COVID-19 patients	25
Antiviral potential of nanoparticles for the treatment of Coronavirus infections	25
Trace and rare earth elements in monofloral and multifloral honeys from Northwestern Italy; A first attempt of characterization by a multi-elemental profile	24
Effects of chromium supplementation on lipid profile in patients with type 2 diabetes: A systematic review and dose-response meta-analysis of randomized controlled trials	23
Toxicity and deleterious impacts of selenium nanoparticles at supranutritional and imbalance levels on male goldfish (Carassius auratus) sperm	23
Iron: Key player in cancer and cell cycle?	23
Trace elements (Al, Cd, Cr, Cu, Fe, Mn, Ni, Pb and Zn) in Mytilus galloprovincialis and Tapes decussatus from Faro and Ganzirri Lakes (Sicily, Italy): Flow cytometry applied for hemocytes analysis	23
Association of dietary and serum selenium concentrations with glucose level and risk of diabetes mellitus: A cross sectional study of national health and nutrition examination survey, 1999-2006	23
Increased expression of zinc transporter ZIP4, ZIP11, ZnT1, and ZnT6 predicts poor prognosis in pancreatic cancer	22
A literature review on beneficial role of vitamins and trace elements: Evidence from published clinical studies	22
Exposure to lead increases the risk of meningioma and brain cancer: A meta-analysis	21
Association of selenium levels with the prevention and control of Keshan disease: A cross-sectional study	21
The role of heavy metals in thyroid cancer: A meta-analysis	21
Rosmarinus officinalis essential oil modulates renal toxicity and oxidative stress induced by potassium dichromate in rats	21
Metal concentrations and metallothionein metal detoxification in blue sharks, Prionace glauca L. from the Western North Atlantic Ocean	20
Effects of dietary nano-selenium supplementation on broiler chicken performance, meat selenium content, intestinal microflora, intestinal morphology, and immune response	20
Room temperature solvent extraction for simple and fast determination of total concentration of Ca, Cu, Fe, Mg, Mn, and Zn in bee pollen by FAAS along with assessment of the bioaccessible fraction of	20
Effect of treatment with silver(I) complex of metronidazole on ocular rosacea: Design and formulation of new silver drug with potent antimicrobial activity	20
Boric acid suppresses cell proliferation by TNF signaling pathway mediated apoptosis in SW-480 human colon cancer line	20
Association between zinc and body composition: An integrative review	19
Association between serum copper/zinc ratio and lung cancer: A systematic review with meta-analysis	19
Heavy metals and trace elements in scalp hair samples of children with severe autism spectrum disorder: A case-control study on Jordanian children	19
The effect of hemodialysis, peritoneal dialysis and renal transplantation on nutritional status and serum micronutrient levels in patients with end-stage renal disease; Multicenter, 6-month period, lo	19
Interplay Between Autophagy and Zinc	19
Anti-cancer effect of boron derivatives on small-cell lung cancer	19
Bromelain from Ananas comosus stem attenuates oxidative toxicity and testicular dysfunction caused by aluminum in rats	18
Hair trace element concentrations in autism spectrum disorder (ASD) and attention deficit/hyperactivity disorder (ADHD)	18
Insight into the pattern of heavy-metal accumulation in lichen thalli	18
Characterization and expression analysis of seven selenoprotein genes in yellow catfish Pelteobagrus fulvidraco to dietary selenium levels	18
Assessment of renal and hepatic dysfunction by co-exposure to toxic metals (Cd, Pb) and fluoride in people living nearby an industrial zone	18
Chemopreventive mechanism of action by oxidative stress and toxicity induced surface decorated selenium nanoparticles	18
Supplementation of antioxidant micronutrients reduces stress and improves immune function/response in periparturient dairy cows and their calves	18
Associations between manganese exposure and multiple immunological parameters in manganese-exposed workers healthy cohort	17
Protective potential of cerium oxide nanoparticles in diabetes mellitus	17
Cross-sectional study: Relationship between serum trace elements and hypertension	17
Zinc-curcumin based complexes in health and diseases: An approach in chemopreventive and therapeutic improvement	17
Supplemental selenium and coenzyme Q10 reduce glycation along with cardiovascular mortality in an elderly population with low selenium status – A four-year, prospective, randomised, double-blind place	17
Antibacterial and antibiofilm efficacy of Ag NPs, Ni NPs and Al2O3 NPs singly and in combination against multidrug-resistant Klebsiella pneumoniae isolates	17
Tailoring the biological response of zirconium implants using zirconia bioceramic coatings: A systematic review	17

Evaluation of parent and nano-encapsulated terbium(III) complex toward its photoluminescence properties, FS-DNA, BSA binding affinity, and biological applications	17
Transport of arsenolipids to the milk of a nursing mother after consuming salmon fish	17
Low hepatic manganese concentrations in patients with hepatic steatosis – A cohort study of copper, iron and manganese in liver biopsies	16
Exploring the role of copper and selenium in the maintenance of normal thyroid function among healthy Koreans	16
Functional role of inorganic trace elements in dentin apatite tissue—Part 1: Mg, Sr, Zn, and Fe	16
Secoisolariciresinol diglucoside protects against cadmium-induced oxidative stress-mediated renal toxicity in rats	16
Relationship between urinary heavy metals with metabolic syndrome and its components in population from Hoveyzeh cohort study: A case-control study in Iran	16
Recent advances in clinical studies of selenium supplementation in radiotherapy	16
The long-term oral exposure to titanium dioxide impaired immune functions and triggered cytotoxic and genotoxic impacts in rats	16
A pilot study of the effects of chromium picolinate supplementation on serum fetuin-A, metabolic and inflammatory factors in patients with nonalcoholic fatty liver disease: A double-blind, placebo-con	16
Plasma levels of trace element status in early pregnancy and the risk of gestational diabetes mellitus: A nested case-control study	16
Exploring mitigating role of zinc nanoparticles on arsenic, ammonia and temperature stress using molecular signature in fish	16
Assessment of the nutritional value of various teas infusions in terms of the macro- and trace elements content	16
Association between trace elements in serum from bipolar disorder and schizophrenia patients considering treatment effects	15
Copper content in ascitic fluid is associated with angiogenesis and progression in ovarian cancer	15
A pilot study to evaluate the levels of aqueous humor trace elements in open-angle glaucoma	15
Methionine-chelated Zn promotes anabolism by integrating mTOR signal and autophagy pathway in juvenile yellow catfish	15
Histopathology changes in the rainbow trout (Onchorhyncus mykiss) consuming boric acid supplemented fish fodder	15
The effect of chromium intake on oxidative stress parameters: A systematic review and meta-analysis	15
Subchronic continuous inhalation exposure to zinc oxide nanoparticles induces pulmonary cell response in mice	15
Synthesis, toxicity evaluation and determination of possible mechanisms of antimicrobial effect of arabinogalactane-capped selenium nanoparticles	15
The possible protective effect of Nano-Selenium on the endocrine and exocrine pancreatic functions in a rat model of acute pancreatitis	15
Trace element imbalances in patients undergoing chronic hemodialysis therapy – Report of an observational study in a cohort of Portuguese patients	15
Protections against toxicity in the brains of rat with chronic fluorosis and primary neurons exposed to fluoride by resveratrol involves nicotinic acetylcholine receptors	15
Effects of storage conditions on the stability and distribution of clinical trace elements in whole blood and plasma: Application of ICP-MS	15
Triad role of hepcidin, ferroportin, and Nrf2 in cardiac iron metabolism: From health to disease	15
Anticancer potential of AgNPs synthesized using Acinetobacter sp. and Curcuma aromatica against HeLa cell lines: A comparative study	14
Mineral and trace element composition of the roe and muscle tissue of farmed rainbow trout (Oncorhynchus mykiss) with respect to nutrient requirements	14
Molecular characterization of ten zinc (Zn) transporter genes and their regulation to Zn metabolism in freshwater teleost yellow catfish Pelteobagrus fulvidraco	14
Boric acid exert anti-cancer effect in poorly differentiated hepatocellular carcinoma cells via inhibition of AKT signaling pathway	14
Trace element, immune and opioid biomarkers of unstable angina, increased atherogenicity and insulin resistance: Results of machine learning	14
Arsenic exposures and prostate cancer risk: A multilevel meta-analysis	14
Iodine status of Turkish pregnant women and their offspring: A national cross-sectional survey	14
Selenium levels and skin diseases: systematic review and meta-analysis	14
Effects of zinc supplementation on inflammatory biomarkers and oxidative stress in adults: A systematic review and meta-analysis of randomized controlled trials	14
The adjuvant aluminum fate – Metabolic tale based on the basics of chemistry and biochemistry	14
Effect of cadmium on the concentration of essential metals in a human chondrocyte micromass culture	13
Zinc nutritional status influences ZnT1 and ZIP4 gene expression in children with a high risk of zinc deficiency	13
Serum trace element levels of gastrointestinal cancer patients in an endemic upper gastrointestinal cancer region	13
The relationship between co-exposure to multiple heavy metals and liver damage	13
Low selenium levels are associated with decreased bone mineral densities	13
Altered clearance of beta-amyloid from the cerebrospinal fluid following subchronic lead exposure in rats: Roles of RAGE and LRP1 in the choroid plexus	13
Serum level of antioxidant vitamins and minerals in patients with vitiligo, a systematic review and meta-analysis	13
Medicinal applications of vanadium complexes with Schiff bases	13
COMMD1, a multi-potent intracellular protein involved in copper homeostasis, protein trafficking, inflammation, and cancer	13
The protective effect of the cardiac thioredoxin system on the heart in the case of iron overload in mice	13
Deposition patterns of iatrogenic lanthanum and gadolinium in the human body depend on delivered chemical binding forms	13
Arsenic and selenium measurements in nail and hair show important relationships to Alzheimer’s disease in the elderly	13
Lead acetate induces hippocampal pyramidal neuron degeneration in mice via up-regulation of executioner caspase-3, oxido-inflammatory stress expression and decreased BDNF and cholinergic activity: Rev	13
Role of NF-κB transcriptional factor activation during chronic fluoride intoxication in development of oxidative-nitrosative stress in rat’s gastric mucosa	13
Zinc availability from zinc-enriched yeast studied with an in vitro digestion/Caco-2 cell culture model	13
Distribution and bioaccumulation of trace elements and lanthanides in apples from Northwestern Italy	13
Effects of acute oral lead exposure on the levels of essential elements of mice: a metallomics and dose-dependent study	13
Association of electronic cigarette use with lead, cadmium, barium, and antimony body burden: NHANES 2015-2016	13
Analysis of neuronal iron deposits in Parkinson's disease brain tissue by synchrotron x-ray spectromicroscopy	13
Single-cell ICP-MS to address the role of trace elements at a cellular level	13
Estimating daily intakes of manganese due to breast milk, infant formulas, or young child nutritional beverages in the United States and France: Comparison to sufficiency and toxicity thresholds	13
Zinc homeostasis plays an important role in the prevention of obesity-induced cardiac inflammation, remodeling and dysfunction	13
Intramedullary implants coated with cubic boron nitride enhance bone fracture healing in a rat model	13
Selenium nanoparticles coupling with Astragalus Polysaccharides exert their cytotoxicities in MCF-7 cells by inhibiting autophagy and promoting apoptosis	13
Chronic copper exposure directs microglia towards degenerative expression signatures in wild-type and J20 mouse model of Alzheimer’s disease	13
Selenium concentration is associated with occurrence and diagnosis of three cardiovascular diseases: A systematic review and meta-analysis	13
Associations between blood metal/ metalloid concentration and human semen quality and sperm function: A cross-sectional study in Hong Kong	12
Trace elements under the spotlight: A powerful nutritional tool in cancer	12
Epidemiology, risk factors across the spectrum of age-related metabolic diseases	12
Chemical elements and preeclampsia - An overview of current problems, challenges and significance of recent research	12
Are fingernail lead levels a reliable biomarker of lead internal dose?	12
Integrated transcriptomic and proteomic analysis indicated that neurotoxicity of rats with chronic fluorosis may be in mechanism involved in the changed cholinergic pathway and oxidative stress	12
Geographical and seasonal variation in iodine content of cow’s milk in the UK and consequences for the consumer´s supply	12
Relationship between selenium status, selenoproteins and COVID-19 and other inflammatory diseases: A critical review	12
Dysregulation of metallothionein and zinc aggravates periodontal diseases	12
Effects of dose and duration of dietary copper administration on hepatic lipid peroxidation and ultrastructure alteration in piglets’ model	12
Mercury in blood, hair, and feces from subsistence fish-eating riverines of the Madeira River Basin (Western Amazon)	12
Elemental metabolomics in human cord blood: Method validation and trace element quantification	12
The role of non-coding RNAs in ferroptosis regulation	12
Possible therapeutic effects of boron citrate and oleoylethanolamide supplementation in patients with COVID-19: A pilot randomized, double-blind, clinical trial	12
Selenium and mercury concentrations in biological samples from patients with COVID-19	12
Metal elements associate with in vitro fertilization (IVF) outcomes in 195 couples	12
Influence of culinary treatment on the concentration and on the bioavailability of cadmium, chromium, copper, and lead in seafood	12
Toxicity of repeated oral intake of organic selenium, inorganic selenium, and selenium nanoparticles: A review	12

Comparison of trace element (selenium, iron), electrolyte (calcium, sodium), and physical activity levels in COVID-19 patients before and after the treatment	12
Use of an antiarrhythmic drug against acute selenium toxicity	11
Zinc deficiency impairs interferon-γ production on post-transcriptional level	11
Relationship between blood cadmium and abdominal aortic calcification: NHANES 2013–2014	11
Effects of boron-containing compounds in the fungal kingdom	11
In vitro effects of boric acid on human liver hepatoma cell line (HepG2) at the half-maximal inhibitory concentration	11
Cu-induced mitochondrial dysfunction is mediated by abnormal mitochondrial fission through oxidative stress in primary chicken embryo hepatocytes	11
Association of lead and cadmium exposure with kidney stone incidence: A study on the non-occupational population in Nandan of China	11
Biodistribution and toxicity assessment of copper nanoparticles in the rat brain	11
Morphine-element interactions – The influence of selected chemical elements on neural pathways associated with addiction	11
Effect of maternal zinc deficiency on offspring health: The epigenetic impact	11
Relationship of levels of trace elements in saliva and dental caries in preschool children using total reflection X-ray fluorescence technique (TXRF)⋆	11
Evaluation of in vitro activity of copper gluconate against SARS-CoV-2 using confocal microscopy-based high content screening	11
Selenium, selenoproteins and cancer of the thyroid	11
Increased oxidative stress and altered serum macro-minerals and trace elements levels are associated with coronary artery disease	11
Evaluation of chronic lead effects in the blood brain barrier system by DCE-CT	11
Trace element homeostasis in the neurological system after SARS-CoV-2 infection: Insight into potential biochemical mechanisms	11
Association of selenium, zinc and copper concentrations during pregnancy with birth weight: A systematic review and meta-analysis	11
Effects of selenium supplementation on diet-induced obesity in mice with a disruption of the selenocysteine lyase gene	11
Determination of eleven small selenium species in human urine by chromatographic-coupled ICP-MS methods	11
Improvement of the antioxidant activity of thyme essential oil against biosynthesized titanium dioxide nanoparticles-induced oxidative stress, DNA damage, and disturbances in gene expression in vivo	11
Synergistically enhanced apoptotic and oxidative DNA damaging pathways in the rat brain with lead and/or aluminum metals toxicity: Expression pattern of genes OGG1 and P53	11
Arsenic and weight loss: At a crossroad between lipogenesis and lipolysis	11
Imbalance in zinc homeostasis enhances lung Tissue Loss following cigarette smoke exposure	11
Antioxidant effects of Se-glutathione peroxidase in alcoholic liver disease	11
Fatty acid desaturation in red blood cell membranes of patients with type 2 diabetes is improved by zinc supplementation	11
Use of human teardrop fluid for the determination of trace elements in healthy individuals and diabetic patients	10
Association of iron-related biomarkers with severity and mortality in COVID-19 patients	10
Involvement of MEK5/ERK5 signaling pathway in manganese-induced cell injury in dopaminergic MN9D cells	10
Serum trace element and amino acid profile in children with cerebral palsy	10
Assessment of chromium species dynamics in root solutions using isotope tracers	10
Emerging role of selenium in treatment of rheumatoid arthritis: An insight on its antioxidant properties	10
Hexavalent chromium-reducing plant growth-promoting rhizobacteria are utilized to bio-fortify trivalent chromium in fenugreek by promoting plant development and decreasing the toxicity of hexavalent c	10
Total mercury in commercial fishes and estimation of Brazilian dietary exposure to methylmercury	10
Boron supplementation in peripartum Murrah buffaloes: The effect on calcium homeostasis, bone metabolism, endocrine and antioxidant status	10
Impact of seminal and serum zinc on semen quality and hormonal status: A population-based cohort study of Russian young men	10
The effect of iron and/or zinc diet supplementation and termination of this practice on the antioxidant status of the reproductive tissues and sperm viability in rats	10
24 h urinary creatinine excretion during pregnancy and its application in appropriate estimation of 24 h urinary iodine excretion	10
Serum copper concentration reflect inflammatory activation in the complex coronary artery disease – A pilot study	10
Elemental measurements and health risk assessment of sub-Saharan African medicinal plants used for cardiovascular diseases’ and related risk factors’ treatment	10
The effect of zinc supplementation on brain derived neurotrophic factor: A meta-analysis	10
Selenium intake and status of postpartum women and postnatal depression during the first year after childbirth in New Zealand – Mother and Infant Nutrition Investigation (MINI) study	10
The concentration and health risk of potentially toxic elements (PTEs) in the breast milk of mothers: a systematic review and meta-analysis	10
MTM1 plays an important role in the regulation of zinc tolerance in Saccharomyces cerevisiae	10
Comparison of blood lead concentrations in patients with acute ischemic stroke and healthy subjects	10
Rare earth cerium oxide nanoparticles attenuated liver fibrosis in bile duct ligation mice model	10
Diversity of effects induced by boron-containing compounds on immune response cells and on antibodies in basal state	10
Trace elements distribution in tropical tree rings through high-resolution imaging using LA-ICP-MS analysis	10
Lead and zinc interactions – An influence of zinc over lead related toxic manifestations	10
Preparation, characteristic and anti-inflammatory effect of selenium nanoparticle-enriched probiotic strain Enterococcus durans A8-1	10
The zebrafish Znt1asa17 mutant reveals roles of zinc transporter-1a in embryonic development	10
The spectrum of pathogenic variants of the ATP7B gene in Wilson disease in the Russian Federation	9
Antigen-specific immunotherapies in type 1 diabetes	9
In vitro anticancer and antibacterial activates of the yttrium(III) complex and its nano-carriers toward DNA cleavage and biological interactions with DNA and BSA; An experimental and computational st	9
Selenium in sediment and food webs of the Tapajós River basin (Brazilian Amazon) and its relation to mercury	9
Association of trace element status in COVID-19 patients with disease severity	9
Effect of aluminum combined with ApoEε4 on Tau phosphorylation and Aβ deposition	9
Reproductive and embryological toxicity of lead acetate in male mice and their offspring and mitigation effects of quercetin	9
A mitophagic response to iron overload-induced oxidative damage associated with the PINK1/Parkin pathway in pancreatic beta cells	9
The effect of the high-fat diet supplemented with various forms of chromium on rats body composition, liver metabolism and organ histology Cr in liver metabolism and histology of selected organs	9
Fluoride exposure and factors affecting dental caries in preschool children living in two areas with different natural levels of fluorides	9
Oral health, organic and inorganic saliva composition of men with Schizophrenia: Case-control study	9
Manganese, iron, copper, and selenium co-exposure and osteoporosis risk in Chinese adults	9
Lead (Pb) exposure induces physiological alterations in the serotoninergic and vasopressin systems causing anxiogenic-like behavior in Meriones shawi: Assessment of BDMC as a neuroprotective compound	9
The impact of bacterial size on their survival in the presence of cationic particles of nano-silver	9
Essential hypertension in patients exposed to high-arsenic exposed areas in western China: Genetic susceptibility and urinary arsenic metabolism characteristics	9
Up-regulation of B-cell lymphoma factor-2 expression, inhibition of oxidative stress and down-regulation of pro-inflammatory cytokines are involved in the protective effect of cabbage (Brassica olerac	9
Serum zinc levels are associated with obesity and low-density lipoprotein cholesterol in Mexican adults	9
Pomegranate juice rescues developmental, neurobehavioral and biochemical disorders in aluminum chloride-treated male mice	9
Effects of boric acid on cell death and oxidative stress of mouse TM3 Leydig cells in vitro	9
Toxic effect of heavy metals on ovarian deformities, apoptotic changes, oxidative stress, and steroid hormones in rainbow trout	9