Development

Article	Citations
The people behind the papers – Yanmei Tao and Zhengdong Wei	119
Pten inhibition dedifferentiates long-distance axon-regenerating intrinsically photosensitive retinal ganglion cells and upregulates mitochondria-associated Dynlt1a and Lars2	111
Zasp52 strengthens whole embryo tissue integrity through supracellular actomyosin networks	109
Harnessing developmental cues for cardiomyocyte production	82
The role of O-GlcNAcylation in development	80
In preprints: new insights into truncated radial glia	80
Alignment of the cell long axis by unidirectional tension acts cooperatively with Wnt signalling to establish planar cell polarity	78
Quantitative videomicroscopy reveals latent control of cell-pair rotations in vivo	76
The people behind the papers – Jake Turley	71
The Forest of Biologists – for biologists, for biology	69
PHLPP1 regulates CFTR activity and lumen expansion through AMPK	65
A new cell culture resource for investigations of reptilian gene function	65
Nup107 contributes to the maternal-to-zygotic transition by preventing the premature nuclear export of pri-miR427	65
Correction: Wt1 transcription factor impairs cardiomyocyte specification and drives a phenotypic switch from myocardium to epicardium	63
Approaches to benchmark and characterize in vitro human model systems	59
FOXC1 and FOXC2 regulate growth plate chondrocyte maturation towards hypertrophy in the embryonic mouse limb skeleton	58
Nutritional control of developmental processes	56
hnRNPH1 establishes Sertoli–germ cell crosstalk through cooperation with PTBP1 and AR, and is essential for male fertility in mice	54
Csf1rb regulates definitive hematopoiesis in zebrafish	52
Testosterone acts through the membrane protein GPRC6A to cause cardiac edema in zebrafish embryos	45
Cerebellum lineage allocation, morphogenesis and repair: impact of interplay amongst cells	43
The AKT1-FOXO4 axis reciprocally regulates hemochorial placentation	43
Aberrant centrosome biogenesis disrupts nephron and collecting duct progenitor growth and fate resulting in fibrocystic kidney disease	42
Normal cell cycle progression requires negative regulation of E2F1 by Groucho during S phase and its relief at G2 phase	42
The people behind the papers – Kelsey Brooks and Shawn Chavez	42

In preprints: retinoic acid degradation and tissue stiffness coordinate axolotl limb regeneration	42
Drosophilaembryos spatially sort their nutrient stores to facilitate their utilization	41
The Excursion	41
Cadherin adhesion complexes direct cell aggregation in the epithelial transition of Wnt-induced nephron progenitor cells	40
The genetic basis of natural variation in the timing of vegetative phase change inArabidopsis thaliana	38
Interplay of SHH, WNT and BMP4 signaling regulates the development of the lamina propria in the murine ureter	38
Developmental and evolutionary comparative analysis of a regulatory landscape in mouse and chicken	37
The combined action of Esrrb and Nr5a2 is essential for murine naïve pluripotency	36
Biased precursor ingression underlies the center-to-pole pattern of male sex determination in mouse	35
Ccn2a-FGFR1-SHH signaling is necessary for intervertebral disc homeostasis and regeneration in adult zebrafish	35
The people behind the papers – Stanley Strawbridge	34
The functional specificity of ERECTA-family receptors in Arabidopsis stomatal development is ensured by molecular chaperones in the endoplasmic reticulum	34
The people behind the papers – Ya Min, Stephanie Conway and Elena Kramer	34
Shared cis-regulatory modules control expression of the tandem paralogs midline and H15 in the follicular epithelium	34
Live imaging of adult zebrafish cardiomyocyte proliferation ex vivo	33
Patterning on the move: the effects of Hh morphogen source movement on signaling dynamics	33
Cdkn1c orchestrates a molecular network that regulates euploidy of male mouse germline stem cells	33
HCR spectral imaging: 10-plex, quantitative, high-resolution RNA and protein imaging in highly autofluorescent samples	32
MIG-23 is involved in sperm migration by modulating extracellular ATP levels in Ascaris suum	32
Abscisic acid biosynthesis is necessary for full auxin effects on hypocotyl elongation	32
Single-cell transcriptional and functional analysis of dopaminergic neurons in organoid-like cultures derived from human fetal midbrain	32
A low-sugar diet enhancesDrosophilabody size in males and females via sex-specific mechanisms	31
Ernest Arenas (1962-2024): a legacy of advancing dopaminergic neurogenesis research	31
Notch-dependent DNAcis-regulatory elements and their dose-dependent control ofC. elegansstem cell self-renewal	31
Single-cell reconstruction with spatial context of migrating neural crest cells and their microenvironments during vertebrate head and neck formation	31
Intrinsic positional memory guides target-specific axon regeneration in the zebrafish vagus nerve	31
Destabilisation of bam transcripts terminates the mitotic phase of Drosophila female germline differentiation	31
Sall4 regulates posterior trunk mesoderm development by promoting mesodermal gene expression and repressing neural genes in the mesoderm	31
The extra-embryonic area opaca plays a role in positioning the primitive streak of the early chick embryo	30
mBeRFP: a versatile fluorescent tool to enhance multichannel live imaging and its applications	30
The Blimp-1 transcription factor acts in non-neuronal cells to regulate terminal differentiation of the Drosophila eye	30
In preprints: shrinking boundary cells reveal fluid flux in organogenesis	30
PBAF chromatin remodeler complexes that mediate meiotic transitions in mouse	30
The insulator BEAF32 controls the spatial-temporal expression profile of the telomeric retrotransposon TART in the Drosophila germline	30
Identification of disease-relevant modulators of the SHH pathway in the developing brain	30
The H2Bub1-deposition complex is required for human and mouse cardiogenesis	30
Destabilization of mRNAs enhances competence to initiate meiosis in mouse spermatogenic cells	30
Modeling mammalian spermatogonial differentiation and meiotic initiationin vitro	29
PPARG contributes to urothelial integrity in the murine ureter by activating the expression of Shh and superficial cell-specific genes	29
rasa1-related arteriovenous malformation is driven by aberrant venous signalling	29
Huntingtin CAG expansion impairs germ layer patterning in synthetic human 2D gastruloids through polarity defects	29
The ERM-1 membrane-binding domain directs erm-1 mRNA localization to the plasma membrane in the C. elegans embryo	29
A lissencephaly-associated BAIAP2 variant causes defects in neuronal migration during brain development	29
Prostate organogenesis	29
PFN4 is required for manchette development and acrosome biogenesis during mouse spermiogenesis	29
The people behind the papers – Julia Grzymkowski and Nanette Nascone-Yoder	29
Multi-view confocal microscopy enables multiple organ and whole organism live-imaging	29
SOX2 transcription factor binding and function	28
Parallels between oncogene-driven cardiac hyperplasia and heart regeneration in zebrafish	28
Krüppel-like factor gene function in the ctenophore Mnemiopsis leidyi assessed by CRISPR/Cas9-mediated genome editing	28

The people behind the papers – Yongjun Yin and David Ornitz	27
The impact of cell size on morphogen gradient precision	27
In preprints: shaping the developing human brain	27
In preprints: new insights into root stem cells and their diversity	27
Insights into the role of immune cells in development and regeneration	27
Transitions in development – an interview with Peng Du	27
Wnt7b expressed by hypertrophic chondrocytes is a stimulatory factor for endochondral ossification that is regulated by Smad4 activity	27
Transitions in development – an interview with Thibaut Brunet	27
Microgel culture and spatial identity mapping elucidate the signalling requirements for primate epiblast and amnion formation	26
An interview with Scott Fraser	26
TIE1-dependent lymphatic vascular remodeling is mediated by its second tyrosine kinase domain	26
Real-time monitoring of an endogenous Fgf8a gradient attests to its role as a morphogen during zebrafish gastrulation	26
Transitions in development – an interview with Antonio Scialdone	26
Maf family transcription factors are required for nutrient uptake in the mouse neonatal gut	26
Sequential and additive expression of miR-9 precursors control timing of neurogenesis	26
Distinct spatiotemporal contribution of morphogenetic events and mechanical tissue coupling during Xenopus neural tube closure	26
Dynamic profiling and functional interpretation of histone lysine crotonylation and lactylation during neural development	25
Ribosome biogenesis and function in development and disease	25
New wave theory	25
Single-cell genomics revolutionizes plant development studies across scales	25
Caenorhabditis elegans LET-381 and DMD-4 control development of the mesodermal HMC endothelial cell	25
Signalling pathway crosstalk stimulated by L-proline drives mouse embryonic stem cells to primitive-ectoderm-like cells	24
The chromatin source-sink hypothesis: a shared mode of chromatin-mediated regulations	24
Contribution of vasculature to stem integrity in Arabidopsis thaliana	24
Single-cell transcriptomics identifies new blood cell populations in Drosophila released at the onset of metamorphosis	24
Microglia refine developing retinal astrocytic and vascular networks through the complement C3/C3aR axis	24
The people behind the papers – Alyshia Scholl, Yihong Liu and Geraldine Seydoux	23
Hindbrain boundaries as niches of neural progenitor and stem cells regulated by the extracellular matrix proteoglycan chondroitin sulphate	23
Galectin-3 promotes the adipogenic differentiation of PDGFRα+ cells and ectopic fat formation in regenerating muscle	23
The people behind the papers – Emily Bulger and Benoit Bruneau	23
Traip controls mushroom body size by suppressing mitotic defects	23
Integrated single-cell multiomics uncovers foundational regulatory mechanisms of lens development and pathology	22
Hemocytes are essential for Drosophila melanogaster post-embryonic development, independent of control of the microbiota	22
Cell-type-specific interacting proteins collaborate to regulate the timing of Cyclin B protein expression in male meiotic prophase	22
A Drosophila toolkit for HA-tagged proteins unveils a block in autophagy flux in the last instar larval fat body	22
The people behind the papers – Alfahdah Alsudayri and Lihua Ye	22
GPR124 regulates murine brain embryonic angiogenesis and BBB formation by an intracellular domain-independent mechanism	22
Keeping up with the Node	22
Anatomy and development of the pectoral fin vascular network in the zebrafish	21
Celsr1 suppresses Wnt5a-mediated chemoattraction to prevent incorrect rostral migration of facial branchiomotor neurons	21
The people behind the papers – Vahid Zadmajid and Daniel Gorelick	21
In preprints: an evo-devo approach integrates multicellular shape diversity and active surface mechanics	21
VitelloTag: a tool for high-throughput cargo delivery into oocytes	21
The Hox code responsible for the patterning of the anterior vertebrae in zebrafish	21
Dynamic de novo adipose tissue development during metamorphosis in Drosophila melanogaster	21
An in vivo CRISPR screen in chick embryos reveals a role for MLLT3 in specification of neural cells from the caudal epiblast	21
Pleiotropy of autism-associated chromatin regulators	21
Cell-cell communication through FGF4 generates and maintains robust proportions of differentiated cell types in embryonic stem cells	21
A transit-amplifying progenitor with biphasic behavior contributes to epidermal renewal	21
Oxygen-sensing mechanisms in development and tissue repair	21
Unlocking the potential of SY-stem cells	20
Systematic expression profiling of Dpr and DIP genes reveals cell surface codes in Drosophila larval motor and sensory neurons	20
Transitions in development – an interview with Daniel Ríos Barrera	20
Normal Table of Xenopus development: a new graphical resource	20
Cell division angle predicts the level of tissue mechanics that tune the amount of cerebellar folding	20
Correction: Transcriptional dynamics during karyogamy in rice zygotes	20
The people behind the papers – Juan Yang and Xuanmao Chen	20
In preprints: lifetime changes in leaf shape	20
Loss of perinuclear theca ACTRT1 causes acrosome detachment and severe male subfertility in mice	20
Conserved roles of ETT and ARF4 in gynoecium development in Brassicaceae with distinct fruit shapes	20
The MEK-ERK signaling pathway promotes maintenance of cardiac chamber identity	20
Advancing stem cell technologies for conservation of wildlife biodiversity	20
Disruption of placental ACKR3 impairs growth and hematopoietic development of offspring	20
Development's 2023 Outstanding Paper Prize	20
Tubb4b is required for multi-ciliogenesis in the mouse	20
Compensation of gene dosage on the mammalian X	20
Duplicated antagonistic EPF peptides optimize grass stomatal initiation	20
FOXP4 differentially controls cold-induced beige adipocyte differentiation and thermogenesis	20
The people behind the papers – Bénédicte Marie Lefèvre and Michael Lang	20
Tissue-specific RNA-seq defines genes governing male tail tip morphogenesis in C. elegans	20
The dynamics of tubulogenesis in development and disease	20
Reduction of cortical parvalbumin-expressing GABAergic interneurons in a rodent hyperoxia model of preterm birth brain injury with deficits in social behavior and cognition	19
In vivo profiling of the Zucchini proximal proteome in the Drosophila ovary	19
The people behind the papers – Dennis de Bakker, Mara Bouwman and Jeroen Bakkers	19
Epha1 is a cell-surface marker for the neuromesodermal competent population	19
LATS1/2 control TGFB-directed epithelial-to-mesenchymal transition in the murine dorsal cranial neuroepithelium through YAP regulation	19
A comparative analysis of TonEBP conditional knockout mouse models reveals inter-dependency between compartments of the intervertebral disc	19
BET activity plays an essential role in control of stem cell attributes in Xenopus	19
Mesenchymal Wnts are required for morphogenetic movements of calvarial osteoblasts during apical expansion	19
The brain on time: links between development and neurodegeneration	19

Transitions in development – an interview with Kara McKinley	19
Different temporal requirements for tartan and wingless in the formation of contractile interfaces at compartmental boundaries	19
Transitions in development – an interview with Evgeny Kvon	19
Quantitative live imaging of floral organ initiation and floral meristem termination in Aquilegia	19
Excess dietary sugar impairs Drosophila adult stem cells via elevated reactive oxygen species-induced JNK signaling	19
Wnt9 directs zebrafish heart tube assembly via a combination of canonical and non-canonical pathway signaling	19
Suppression of YAP safeguards human naïve pluripotency	19
Lineage-based scaling of germline intercellular bridges during oogenesis	19
Interaction of Gαi2 with EB1 controls microtubule dynamics and Rac1 activity in Xenopus neural crest cell migration	18
E93 is indispensable for reproduction in ametabolous and hemimetabolous insects	18
osr1couples intermediate mesoderm cell fate with temporal dynamics of vessel progenitor cell differentiation	18
An inducible germ cell ablation chicken model for high-grade germline chimeras	18
Msl3 promotes germline stem cell differentiation in female Drosophila	18
Multiple cis-regulatory elements control prox1a expression in distinct lymphatic vascular beds	18
Elevated numbers of infiltrating eosinophils accelerate the progression of Duchenne muscular dystrophy pathology in mdx mice	18
Drosophila CTP synthase regulates collective cell migration by controlling the polarized endocytic cycle	18
Cleaved Delta like 1 intracellular domain regulates neural development via Notch signal-dependent and -independent pathways	18
Transitions in development – an interview with Salah Elias	18
FAM71F1 binds to RAB2A and RAB2B and is essential for acrosome formation and male fertility in mice	18
Correction: Zebrafish dazl regulates cystogenesis and germline stem cell specification during the primordial germ cell to germline stem cell transition	18
Confinement promotes nematic alignment of spindle-shaped cells during Drosophila embryogenesis	18
Single-minded 2 is required for left-right asymmetric stomach morphogenesis	18
Control of dynamic cell behaviors during angiogenesis and anastomosis by Rasip1	18
Cranium growth, patterning and homeostasis	18
In preprints: the extracellular matrix influences primordial germ cell behavior	18
Notch signaling in neurogenesis	18
A renaissance for developmental biology driven by new in vitro platforms	17
PUF-8, a C. elegans ortholog of the RNA-binding proteins PUM1 and PUM2, is required for robustness of the cell death fate	17
Dissecting pleiotropic functions of the wheat Green Revolution gene Rht-B1b in plant morphogenesis and yield formation	17
An ancient testis-specific IQ motif-containing H gene regulates specific transcript isoform expression during spermatogenesis	17
The RNA ligase RNA terminal phosphate cyclase B regulates mRNA alternative splicing and is required for mouse oocyte development and maintenance	17
The miR156 juvenility factor and PLETHORA 2 form a regulatory network and influence timing of meristem growth and lateral root emergence	17
NHR-23 activity is necessary for C. elegans developmental progression and apical extracellular matrix structure and function	17
Direct force measurement and loading on developing tissues in intact avian embryos	17
Cyclical endometrial repair and regeneration	17
Pathway to Independence – an interview with Clémentine Villeneuve	17
Expanding the evo-devo toolkit: generation of 3D mammary tissue from diverse mammals	17
Sculpting with stem cells: how models of embryo development take shape	17
Mammalian DNA methylome dynamics: mechanisms, functions and new frontiers	17
Pathway to Independence – an interview with Marcella Birtele	17
Gibberellin and miRNA156-targeted SlSBP genes synergistically regulate tomato floral meristem determinacy and ovary patterning	16
The DOT1L-MLLT10 complex regulates male fertility and promotes histone removal during spermiogenesis	16
Control of fate specification within the dorsal head of Drosophila melanogaster	16
The people behind the papers – Justina Stark, Ivo Sbalzarini and Michael Brand	16
Sensory nerve regulates progenitor cells via FGF-SHH axis in tooth root morphogenesis	16
A conserved role of the Hippo signalling pathway in initiation of the first lineage specification event across mammals	16
Evolution of the regulation of developmental gene expression in blind Mexican cavefish	16
A constitutively expressed fluorescent ubiquitination-based cell-cycle indicator (FUCCI) in axolotls for studying tissue regeneration	16
Cre recombinase microinjection for single-cell tracing and localised gene targeting	16
The cell adhesion molecule Echinoid promotes tissue survival and separately restricts tissue overgrowth	16
regeneration factors expressed on myeloid expression in macrophage-like cells is required for tail regeneration in Xenopus laevis tadpoles	16
De novo PAM generation to reach initially inaccessible target sites for base editing	16
Adipose triglyceride lipase promotes prostaglandin-dependent actin remodeling by regulating substrate release from lipid droplets	16
Motor neurons in the tunicate caudal central nervous system reveal homology to the vertebrate spinal cord	16
Y box-binding protein 1 regulates zebrafish folliculogenesis partly through p21-mediated control of follicle cell proliferation	16
The exocyst complex regulates C. elegans germline stem cell proliferation by controlling membrane Notch levels	16
Environmental and molecular control of tissue-specific ionocyte differentiation in zebrafish	16
Pivotal role of STIP in ovule pattern formation and female germline development in Arabidopsis thaliana	16
An end-to-end pipeline based on open source deep learning tools for reliable analysis of complex 3D images of ovaries	16
Development of the mammalian main olfactory bulb	16
A high-sugar diet, but not obesity, reduces female fertility in Drosophila melanogaster	16
Orb-dependent polyadenylation contributes to PLP expression and centrosome scaffold assembly	16
Exploring the principles of embryonic mammary gland branching morphogenesis	16
The cellular function of ROP GTPase prenylation is important for multicellularity in the moss Physcomitrium patens	16
Enhancer RNAs step forward: new insights into enhancer function	16
An interview with Mayssa Mokalled	16
PLETHORA transcription factors promote early embryo development through induction of meristematic potential	16
IL7Rα, but not Flk2, is required for hematopoietic stem cell reconstitution of tissue-resident lymphoid cells	16
New year, new developments: a look back and a look ahead	16
Transplanted human intestinal organoids: a resource for modeling human intestinal development	16
TAF4b transcription networks regulating early oocyte differentiation	15
Reelin differentially shapes dendrite morphology of medial entorhinal cortical ocean and island cells	15
Progression of the pluripotent epiblast depends upon the NMD factor UPF2	15
The people behind the papers – Wendy Duan and Meghan Riddell	15
Intermediate progenitor cells provide a transition between hematopoietic progenitors and their differentiated descendants	15
Induced regeneration of articular cartilage – identification of a dormant regeneration program for a non-regenerative tissue	15
Intercellular contact and cargo transfer between Müller glia and to microglia precede apoptotic cell clearance in the developing retina	15
Astrocyte-intrinsic and -extrinsic Fat1 activities regulate astrocyte development and angiogenesis in the retina	15
The people behind the papers – Masaki Kinoshita, Toshihiro Kobayashi, Hiroshi Nagashima, Ramiro Alberio and Austin Smith	15
Live 3D imaging and mapping of shear stresses within tissues using incompressible elastic beads	15
Correction: A single-plasmid approach for genome editing coupled with long-term lineage analysis in chick embryos	15
Gut microbiota regulate maturation and mitochondrial function of the nutrient-sensing enteroendocrine cell	15
The fetal lineage is susceptible to Zika virus infection within days of fertilization	15
An elastic proteinaceous envelope encapsulates the early Arabidopsis embryo	15
A method for stabilising the XX karyotype in female mESC cultures	15
Sall1 and Sall4 cooperatively interact with Myocd and SRF to promote cardiomyocyte proliferation by regulating CDK and cyclin genes	15
Mechanical stress combines with planar polarised patterning during metaphase to orient embryonic epithelial cell divisions	15
Human developmental biology – a global perspective	15
Nr4a1 modulates inflammation and heart regeneration in zebrafish	15
Modeling development using hydrogels	15
The class VIII myosin ATM1 is required for root apical meristem function	15
Live imaging of retinotectal mapping reveals topographic map dynamics and a previously undescribed role for Contactin 2 in map sharpening	15
A Rad50-null mutation in mouse germ cells causes reduced DSB formation, abnormal DSB end resection and complete loss of germ cells	15
The people behind the papers – Masahito Irie, Fumitoshi Ishino and Tomoko Kaneko-Ishino	15
Cadherin-dependent adhesion is required for muscle stem cell niche anchorage and maintenance	15