Development

Article	Citations
The people behind the papers – Stanley Strawbridge	130
The people behind the papers – Ya Min, Stephanie Conway and Elena Kramer	120
Aberrant centrosome biogenesis disrupts nephron and collecting duct progenitor growth and fate resulting in fibrocystic kidney disease	97
The Excursion	90
Cerebellum lineage allocation, morphogenesis and repair: impact of interplay amongst cells	85
Biased precursor ingression underlies the center-to-pole pattern of male sex determination in mouse	84
Shared cis-regulatory modules control expression of the tandem paralogs midline and H15 in the follicular epithelium	83
The functional specificity of ERECTA-family receptors in Arabidopsis stomatal development is ensured by molecular chaperones in the endoplasmic reticulum	77
Interplay of SHH, WNT and BMP4 signaling regulates the development of the lamina propria in the murine ureter	75
HCR spectral imaging: 10-plex, quantitative, high-resolution RNA and protein imaging in highly autofluorescent samples	75
The genetic basis of natural variation in the timing of vegetative phase change inArabidopsis thaliana	70
Quantitative videomicroscopy reveals latent control of cell-pair rotations in vivo	67
Frozen potential: embryo research at the crossroads of ethics, regulation and scientific opportunity	65
The people behind the papers – Kelsey Brooks and Shawn Chavez	60
Cdkn1c orchestrates a molecular network that regulates euploidy of male mouse germline stem cells	54
MIG-23 is involved in sperm migration by modulating extracellular ATP levels in Ascaris suum	50
Ernest Arenas (1962-2024): a legacy of advancing dopaminergic neurogenesis research	49
Destabilisation of bam transcripts terminates the mitotic phase of Drosophila female germline differentiation	49
In preprints: new insights into truncated radial glia	45
The people behind the papers – Jake Turley	45
The Forest of Biologists – for biologists, for biology	44
Nup107 contributes to the maternal-to-zygotic transition by preventing the premature nuclear export of pri-miR427	42
The AKT1-FOXO4 axis reciprocally regulates hemochorial placentation	42
Correction: Wt1 transcription factor impairs cardiomyocyte specification and drives a phenotypic switch from myocardium to epicardium	42
Normal cell cycle progression requires negative regulation of E2F1 by Groucho during S phase and its relief at G2 phase	41

In preprints: retinoic acid degradation and tissue stiffness coordinate axolotl limb regeneration	40
Testosterone acts through the membrane protein GPRC6A to cause cardiac edema in zebrafish embryos	39
Csf1rb regulates definitive hematopoiesis in zebrafish	39
Zasp52 strengthens whole embryo tissue integrity through supracellular actomyosin networks	38
The people behind the papers – Yanmei Tao and Zhengdong Wei	37
Adhesion strength, cell packing density and cell surface buckling in pericellular matrix-mediated tissue cohesion	37
A new cell culture resource for investigations of reptilian gene function	36
Pten inhibition dedifferentiates long-distance axon-regenerating intrinsically photosensitive retinal ganglion cells and upregulates mitochondria-associated Dynlt1a and Lars2	36
Abscisic acid biosynthesis is necessary for full auxin effects on hypocotyl elongation	35
An interview with Meritxell (Meri) Huch	35
PHLPP1 regulates CFTR activity and lumen expansion through AMPK	35
Notch-dependent DNAcis-regulatory elements and their dose-dependent control ofC. elegansstem cell self-renewal	35
Approaches to benchmark and characterize in vitro human model systems	34
Cadherin adhesion complexes direct cell aggregation in the epithelial transition of Wnt-induced nephron progenitor cells	34
Sall4 regulates posterior trunk mesoderm development by promoting mesodermal gene expression and repressing neural genes in the mesoderm	34
Developmental and evolutionary comparative analysis of a regulatory landscape in mouse and chicken	33
Patterning on the move: the effects of Hh morphogen source movement on signaling dynamics	33
hnRNPH1 establishes Sertoli–germ cell crosstalk through cooperation with PTBP1 and AR, and is essential for male fertility in mice	33
Single-cell transcriptional and functional analysis of dopaminergic neurons in organoid-like cultures derived from human fetal midbrain	32
Nutritional control of developmental processes	32
Harnessing developmental cues for cardiomyocyte production	32
Ccn2a-FGFR1-SHH signaling is necessary for intervertebral disc homeostasis and regeneration in adult zebrafish	32
A low-sugar diet enhancesDrosophilabody size in males and females via sex-specific mechanisms	32
FOXC1 and FOXC2 regulate growth plate chondrocyte maturation towards hypertrophy in the embryonic mouse limb skeleton	32
Alignment of the cell long axis by unidirectional tension acts cooperatively with Wnt signalling to establish planar cell polarity	31
The role of O-GlcNAcylation in development	31
Maf family transcription factors are required for nutrient uptake in the mouse neonatal gut	31
Drosophilaembryos spatially sort their nutrient stores to facilitate their utilization	31
The people behind the papers – Yongjun Yin and David Ornitz	30
Transitions in development – an interview with Thibaut Brunet	30
The impact of cell size on morphogen gradient precision	30
Multi-view confocal microscopy enables multiple organ and whole organism live-imaging	30
Transitions in development – an interview with Peng Du	30
Insights into the role of immune cells in development and regeneration	30
An interview with Scott Fraser	30
In preprints: new insights into root stem cells and their diversity	30
In preprints: shaping the developing human brain	30
The people behind the papers – Julia Grzymkowski and Nanette Nascone-Yoder	29
PPARG contributes to urothelial integrity in the murine ureter by activating the expression of Shh and superficial cell-specific genes	29
In preprints: shrinking boundary cells reveal fluid flux in organogenesis	29
The Blimp-1 transcription factor acts in non-neuronal cells to regulate terminal differentiation of the Drosophila eye	29
Microgel culture and spatial identity mapping elucidate the signalling requirements for primate epiblast and amnion formation	28
Supracellular actomyosin assemblies: master coordinators of development	28
Pervasive homeobox gene function in the male-specific nervous system of Caenorhabditis elegans	28
Parallels between oncogene-driven cardiac hyperplasia and heart regeneration in zebrafish	28
Modeling mammalian spermatogonial differentiation and meiotic initiationin vitro	28
The extra-embryonic area opaca plays a role in positioning the primitive streak of the early chick embryo	28
Circadian clock genes perform dual roles as systemic oscillators and context-dependent regulators	28
PBAF chromatin remodeler complexes that mediate meiotic transitions in mouse	28
Wnt7b expressed by hypertrophic chondrocytes is a stimulatory factor for endochondral ossification that is regulated by Smad4 activity	28

mBeRFP: a versatile fluorescent tool to enhance multichannel live imaging and its applications	27
A lissencephaly-associated BAIAP2 variant causes defects in neuronal migration during brain development	27
Transitions in development – an interview with Antonio Scialdone	27
SOX2 transcription factor binding and function	27
Single-cell reconstruction with spatial context of migrating neural crest cells and their microenvironments during vertebrate head and neck formation	26
Real-time monitoring of an endogenous Fgf8a gradient attests to its role as a morphogen during zebrafish gastrulation	26
Distinct spatiotemporal contribution of morphogenetic events and mechanical tissue coupling during Xenopus neural tube closure	26
Prostate organogenesis	26
Destabilization of mRNAs enhances competence to initiate meiosis in mouse spermatogenic cells	26
Sequential and additive expression of miR-9 precursors control timing of neurogenesis	25
rasa1-related arteriovenous malformation is driven by aberrant venous signalling	25
The H2Bub1-deposition complex is required for human and mouse cardiogenesis	25
The ratio of Wnt signaling activity to Sox2 transcription factor levels predicts neuromesodermal fate potential	25
TIE1-dependent lymphatic vascular remodeling is mediated by its second tyrosine kinase domain	24
The insulator BEAF32 controls the spatial-temporal expression profile of the telomeric retrotransposon TART in the Drosophila germline	24
Celsr1 suppresses Wnt5a-mediated chemoattraction to prevent incorrect rostral migration of facial branchiomotor neurons	24
Ribosome biogenesis and function in development and disease	24
The ERM-1 membrane-binding domain directs erm-1 mRNA localization to the plasma membrane in the C. elegans embryo	24
Single-cell genomics revolutionizes plant development studies across scales	24
PFN4 is required for manchette development and acrosome biogenesis during mouse spermiogenesis	24
Dynamic profiling and functional interpretation of histone lysine crotonylation and lactylation during neural development	24
Disruption of placental ACKR3 impairs growth and hematopoietic development of offspring	24
Oxygen-sensing mechanisms in development and tissue repair	23
Signalling pathway crosstalk stimulated by L-proline drives mouse embryonic stem cells to primitive-ectoderm-like cells	23
The chromatin source-sink hypothesis: a shared mode of chromatin-mediated regulations	23
The people behind the papers – Bénédicte Marie Lefèvre and Michael Lang	23
New wave theory	23
Cell division angle predicts the level of tissue mechanics that tune the amount of cerebellar folding	23
The people behind the papers – Vahid Zadmajid and Daniel Gorelick	23
Keeping up with the Node	23
TOR signalling mediates the collective movement of border cells in Drosophila oogenesis	23
The people behind the papers – Alfahdah Alsudayri and Lihua Ye	23
In preprints: an evo-devo approach integrates multicellular shape diversity and active surface mechanics	23
An in vivo CRISPR screen in chick embryos reveals a role for MLLT3 in specification of neural cells from the caudal epiblast	23
The people behind the papers – Alyshia Scholl, Yihong Liu and Geraldine Seydoux	23
The people behind the papers – Emily Bulger and Benoit Bruneau	23
The Hox code responsible for the patterning of the anterior vertebrae in zebrafish	22
The people behind the papers – Keiji Itoh and Sergei Sokol	22
A transit-amplifying progenitor with biphasic behavior contributes to epidermal renewal	22
VitelloTag: a tool for high-throughput cargo delivery into oocytes	22
Hindbrain boundaries as niches of neural progenitor and stem cells regulated by the extracellular matrix proteoglycan chondroitin sulphate	22
Correction: Single-cell organogenesis captures complex breast tissue formation in three dimensions	22
The MEK-ERK signaling pathway promotes maintenance of cardiac chamber identity	22
Pathway to Independence – an interview with Toshimichi Yamada	22
Galectin-3 promotes the adipogenic differentiation of PDGFRα+ cells and ectopic fat formation in regenerating muscle	22
Anatomy and development of the pectoral fin vascular network in the zebrafish	21
Caenorhabditis elegans LET-381 and DMD-4 control development of the mesodermal HMC endothelial cell	21
Contribution of vasculature to stem integrity in Arabidopsis thaliana	21
GPR124 regulates murine brain embryonic angiogenesis and BBB formation by an intracellular domain-independent mechanism	21
Cell-cell communication through FGF4 generates and maintains robust proportions of differentiated cell types in embryonic stem cells	21
Hemocytes are essential for Drosophila melanogaster post-embryonic development, independent of control of the microbiota	21
Integrated single-cell multiomics uncovers foundational regulatory mechanisms of lens development and pathology	21
A Drosophila toolkit for HA-tagged proteins unveils a block in autophagy flux in the last instar larval fat body	21
Microglia refine developing retinal astrocytic and vascular networks through the complement C3/C3aR axis	21
Advancing stem cell technologies for conservation of wildlife biodiversity	21
Single-cell organogenesis captures complex breast tissue formation in three dimensions	21
Traip controls mushroom body size by suppressing mitotic defects	21
Pleiotropy of autism-associated chromatin regulators	21
Transitions in development – an interview with Salah Elias	20
Transitions in development – an interview with Daniel Ríos Barrera	20
The people behind the papers – Juan Yang and Xuanmao Chen	20
Unlocking the potential of SY-stem cells	20
Multiple cis-regulatory elements control prox1a expression in distinct lymphatic vascular beds	20
Generative model for the first cell fate bifurcation in mammalian development	20
Correction: Zebrafish dazl regulates cystogenesis and germline stem cell specification during the primordial germ cell to germline stem cell transition	20
The people behind the papers – Danielle Spitzer and Iswar Hariharan	20
Cranium growth, patterning and homeostasis	20
FOXP4 differentially controls cold-induced beige adipocyte differentiation and thermogenesis	20
Development's 2023 Outstanding Paper Prize	20
In preprints: the extracellular matrix influences primordial germ cell behavior	20
Cell-type-specific interacting proteins collaborate to regulate the timing of Cyclin B protein expression in male meiotic prophase	20
Dynamic de novo adipose tissue development during metamorphosis in Drosophila melanogaster	20
Pathway to Independence – an interview with Clémentine Villeneuve	20
Conserved roles of ETT and ARF4 in gynoecium development in Brassicaceae with distinct fruit shapes	20
Correction: Transcriptional dynamics during karyogamy in rice zygotes	20
In preprints: lifetime changes in leaf shape	20
Single-cell transcriptomics identifies new blood cell populations in Drosophila released at the onset of metamorphosis	20
Epha1 is a cell-surface marker for the neuromesodermal competent population	20
Normal Table of Xenopus development: a new graphical resource	20
Compensation of gene dosage on the mammalian X	20

BET activity plays an essential role in control of stem cell attributes in Xenopus	19
Interaction of Gαi2 with EB1 controls microtubule dynamics and Rac1 activity in Xenopus neural crest cell migration	19
Tissue-specific RNA-seq defines genes governing male tail tip morphogenesis in C. elegans	19
The dynamics of tubulogenesis in development and disease	19
Lineage-based scaling of germline intercellular bridges during oogenesis	19
Transitions in development – an interview with Evgeny Kvon	19
Transitions in development – an interview with Kara McKinley	19
Notch signaling in neurogenesis	19
Confinement promotes nematic alignment of spindle-shaped cells during Drosophila embryogenesis	19
A comparative analysis of TonEBP conditional knockout mouse models reveals inter-dependency between compartments of the intervertebral disc	19
Mesenchymal Wnts are required for morphogenetic movements of calvarial osteoblasts during apical expansion	19
Drosophila CTP synthase regulates collective cell migration by controlling the polarized endocytic cycle	19
Systematic expression profiling of Dpr and DIP genes reveals cell surface codes in Drosophila larval motor and sensory neurons	19
Elevated numbers of infiltrating eosinophils accelerate the progression of Duchenne muscular dystrophy pathology in mdx mice	18
E93 is indispensable for reproduction in ametabolous and hemimetabolous insects	18
Wnt9 directs zebrafish heart tube assembly via a combination of canonical and non-canonical pathway signaling	18
LATS1/2 control TGFB-directed epithelial-to-mesenchymal transition in the murine dorsal cranial neuroepithelium through YAP regulation	18
In vivo profiling of the Zucchini proximal proteome in the Drosophila ovary	18
Mammalian DNA methylome dynamics: mechanisms, functions and new frontiers	18
Suppression of YAP safeguards human naïve pluripotency	18
Excess dietary sugar impairs Drosophila adult stem cells via elevated reactive oxygen species-induced JNK signaling	18
Loss of perinuclear theca ACTRT1 causes acrosome detachment and severe male subfertility in mice	18
An inducible germ cell ablation chicken model for high-grade germline chimeras	18
The brain on time: links between development and neurodegeneration	18
Msl3 promotes germline stem cell differentiation in female Drosophila	18
Different temporal requirements for tartan and wingless in the formation of contractile interfaces at compartmental boundaries	18
Environmental and molecular control of tissue-specific ionocyte differentiation in zebrafish	18
Tubb4b is required for multi-ciliogenesis in the mouse	18
Direct force measurement and loading on developing tissues in intact avian embryos	18
Quantitative live imaging of floral organ initiation and floral meristem termination in Aquilegia	18
The RNA ligase RNA terminal phosphate cyclase B regulates mRNA alternative splicing and is required for mouse oocyte development and maintenance	17
Expanding the evo-devo toolkit: generation of 3D mammary tissue from diverse mammals	17
Cre recombinase microinjection for single-cell tracing and localised gene targeting	17
PUF-8, a C. elegans ortholog of the RNA-binding proteins PUM1 and PUM2, is required for robustness of the cell death fate	17
Evolution of the regulation of developmental gene expression in blind Mexican cavefish	17
An ancient testis-specific IQ motif-containing H gene regulates specific transcript isoform expression during spermatogenesis	17
Orb-dependent polyadenylation contributes to PLP expression and centrosome scaffold assembly	17
The people behind the papers – Justina Stark, Ivo Sbalzarini and Michael Brand	17
Ectodysplasin overexpression reveals spatiotemporally dynamic tooth formation competency in stickleback and zebrafish	17
PLETHORA transcription factors promote early embryo development through induction of meristematic potential	17
New year, new developments: a look back and a look ahead	17
Pathway to Independence – an interview with Marcella Birtele	17
regeneration factors expressed on myeloid expression in macrophage-like cells is required for tail regeneration in Xenopus laevis tadpoles	17
A renaissance for developmental biology driven by new in vitro platforms	17
De novo PAM generation to reach initially inaccessible target sites for base editing	17
Exploring the principles of embryonic mammary gland branching morphogenesis	17
NHR-23 activity is necessary for C. elegans developmental progression and apical extracellular matrix structure and function	17
Transplanted human intestinal organoids: a resource for modeling human intestinal development	17
Adipose triglyceride lipase promotes prostaglandin-dependent actin remodeling by regulating substrate release from lipid droplets	16
Motor neurons in the tunicate caudal central nervous system reveal homology to the vertebrate spinal cord	16
Enhancer RNAs step forward: new insights into enhancer function	16
A Rad50-null mutation in mouse germ cells causes reduced DSB formation, abnormal DSB end resection and complete loss of germ cells	16
Differential proliferation regulates multi-tissue morphogenesis during embryonic axial extension: integrating viscous modeling and experimental approaches	16
A high-sugar diet, but not obesity, reduces female fertility in Drosophila melanogaster	16
egal-1 and microtubules promote regeneration polarity in planarians	16
A conserved role of the Hippo signalling pathway in initiation of the first lineage specification event across mammals	16
The cellular function of ROP GTPase prenylation is important for multicellularity in the moss Physcomitrium patens	16
IL7Rα, but not Flk2, is required for hematopoietic stem cell reconstitution of tissue-resident lymphoid cells	16
Pivotal role of STIP in ovule pattern formation and female germline development in Arabidopsis thaliana	16
Building and rebuilding complex tissues: strategic visions from a research-led workshop	16
Signals from the head and germinative region differentially regulate regeneration competence of the tapeworm Hymenolepis diminuta	16
Thymic epithelial organoids mediate T-cell development	16
Sensory nerve regulates progenitor cells via FGF-SHH axis in tooth root morphogenesis	16
Dissecting pleiotropic functions of the wheat Green Revolution gene Rht-B1b in plant morphogenesis and yield formation	16
The people behind the papers – Taishi Fujimura and Isao Tamura	16
A constitutively expressed fluorescent ubiquitination-based cell-cycle indicator (FUCCI) in axolotls for studying tissue regeneration	16
The DOT1L-MLLT10 complex regulates male fertility and promotes histone removal during spermiogenesis	16
Development of the mammalian main olfactory bulb	16
Gibberellin and miRNA156-targeted SlSBP genes synergistically regulate tomato floral meristem determinacy and ovary patterning	16
The cell-adhesion molecule Echinoid promotes tissue survival and separately restricts tissue overgrowth	16
Live imaging of retinotectal mapping reveals topographic map dynamics and a previously undescribed role for Contactin 2 in map sharpening	16
Heme-deficient primitive red blood cells induce HSPC ferroptosis by altering iron homeostasis during zebrafish embryogenesis	16
blf and the drl cluster synergistically regulate cell fate commitment during zebrafish primitive hematopoiesis	16
The miR156 juvenility factor and PLETHORA 2 form a regulatory network and influence timing of meristem growth and lateral root emergence	16
Control of fate specification within the dorsal head of Drosophila melanogaster	16
An end-to-end pipeline based on open source deep learning tools for reliable analysis of complex 3D images of ovaries	16
Sculpting with stem cells: how models of embryo development take shape	16
Nr4a1 modulates inflammation and heart regeneration in zebrafish	15
TAF4b transcription networks regulating early oocyte differentiation	15
The people behind the papers – Masahito Irie, Fumitoshi Ishino and Tomoko Kaneko-Ishino	15
Heterologous expression of a lycophyte protein enhances angiosperm seedling vigor	15
Rac1 and Nectin3 are essential for planar cell polarity-directed axon guidance in the peripheral auditory system	15
Human developmental biology – a global perspective	15
Human stem cell models to study placode development, function and pathology	15
Notch signaling regulates neural stem cell quiescence entry and exit in Drosophila	15
From genes to patterns: five key dynamical systems concepts to decode developmental regulatory mechanisms	15
Retrovirus-derived RTL5 and RTL6 genes are novel constituents of the innate immune system in the eutherian brain	15
The people behind the papers – Wendy Duan and Meghan Riddell	15
Constructive Critics: Development's approach to peer review	15
Sall1 and Sall4 cooperatively interact with Myocd and SRF to promote cardiomyocyte proliferation by regulating CDK and cyclin genes	15
Modeling development using hydrogels	15
Female meiosis II and pronuclear fusion require the microtubule transport factor Bicaudal D	15
The people behind the papers – Jonas Malkmus, Rushikesh Sheth and Rolf Zeller	15
Development's 2024 outstanding paper prize	15
The fetal lineage is susceptible to Zika virus infection within days of fertilization	15