Oncogene

Article	Citations
Retraction Note: The molecular mechanism of microRNA-145 to suppress invasion-metastasis cascade in gastric cancer	176
Retraction Note: HBx/ERα complex-mediated LINC01352 downregulation promotes HBV-related hepatocellular carcinoma via the miR-135b-APC axis	169
Retraction Note: Human papillomavirus type 77 E6 protein selectively inhibits p53-dependent transcription of proapoptotic genes following UV-B irradiation	142
Retraction Note: Upregulation of long noncoding RNA ZEB1-AS1 promotes tumor metastasis and predicts poor prognosis in hepatocellular carcinoma	137
Retraction Note: RNA interference targeting the M2 subunit of ribonucleotide reductase enhances pancreatic adenocarcinoma chemosensitivity to gemcitabine	132
Retraction Note: Genetic alterations of the NRP/B gene are associated with human brain tumors	129
Retraction Note: CEACAM6 gene silencing impairs anoikis resistance and in vivo metastatic ability of pancreatic adenocarcinoma cells	127
RBMS3-loss impedes TRIM21-induced ubiquitination of ANGPT2 in an RNA-independent manner and drives sorafenib resistance in hepatocellular carcinoma	126
Downregulation of HINFP induces senescence-associated secretory phenotype to promote metastasis in a non-cell-autonomous manner in bladder cancer	107
SIK2 maintains breast cancer stemness by phosphorylating LRP6 and activating Wnt/β-catenin signaling	102
Molecular profiling of signet-ring-cell carcinoma (SRCC) from the stomach and colon reveals potential new therapeutic targets	102
Targeting non-canonical activation of GLI1 by the SOX2-BRD4 transcriptional complex improves the efficacy of HEDGEHOG pathway inhibition in melanoma	100
TRAIP suppresses bladder cancer progression by catalyzing K48-linked polyubiquitination of MYC	98
Alcohol-induced C/EBP β-driven VIRMA decreases oxidative stress and promotes pancreatic ductal adenocarcinoma growth and metastasis via the m6A/YTHDF2/SLC43A2 pathway	93
Correction: p73 and caspase-cleaved p73 fragments localize to mitochondria and augment TRAIL-induced apoptosis	87
Retraction Note to: FOXC2 promotes colorectal cancer metastasis by directly targeting MET	83
Ferroptosis as a mechanism to mediate p53 function in tumor radiosensitivity	81
Editorial Expression of Concern: Biologic sequelae of interleukin-6 induced PI3-K/Akt signaling in multiple myeloma	81
The lncRNA THOR interacts with and stabilizes hnRNPD to promote cell proliferation and metastasis in breast cancer	77
Hypoxia induces chemoresistance to proteasome inhibitors through orchestrating deSUMOylation and ubiquitination of SRC-3 in multiple myeloma	77
MUC1-C activates the PBAF chromatin remodeling complex in integrating redox balance with progression of human prostate cancer stem cells	77
Discovery of a dual WDR5 and Ikaros PROTAC degrader as an anti-cancer therapeutic	70
Correction: BRD4-specific PROTAC inhibits basal-like breast cancer partially through downregulating KLF5 expression	69
ITLN1 inhibits tumor neovascularization and myeloid derived suppressor cells accumulation in colorectal carcinoma	69
Gamma-glutamyltransferase 7 suppresses gastric cancer by cooperating with RAB7 to induce mitophagy	68

SENP1-mediated deSUMOylation of YBX1 promotes colorectal cancer development through the SENP1-YBX1-AKT signaling axis	68
FAK-LINC01089 negative regulatory loop controls chemoresistance and progression of small cell lung cancer	66
Correction: Androgen receptor promotes renal cell carcinoma (RCC) vasculogenic mimicry (VM) via altering TWIST1 nonsense-mediated decay through lncRNA-TANAR	65
USP11 potentiates HGF/AKT signaling and drives metastasis in hepatocellular carcinoma	65
SOX10 deficiency-mediated LAMB3 upregulation determines the invasiveness of MAPKi-resistant melanoma	64
Flotillin-1 palmitoylation is essential for its stability and subsequent tumor promoting capabilities	62
An integrated ceRNA network identifies miR-375 as an upregulated miRNA playing a tumor suppressive role in aggressive prostate cancer	61
ZEB1 controls a lineage-specific transcriptional program essential for melanoma cell state transitions	61
CRL2KLHDC3 and CRL1Fbxw7 cooperatively mediate c-Myc degradation	61
COL5A1 promotes triple-negative breast cancer progression by activating tumor cell-macrophage crosstalk	60
Correction: Notch3-regulated microRNAs impair CXCR4-dependent maturation of thymocytes allowing maintenance and progression of T-ALL	59
Suppression of lysosome metabolism-meditated GARP/TGF-β1 complexes specifically depletes regulatory T cells to inhibit breast cancer metastasis	59
Correction: Regulation of cancer stem cell activity by thyroid hormone receptor β	58
Loss of RNA-binding protein CELF2 promotes acute leukemia development via FAT10-mTORC1	57
Mapping the breast tumor microenvironment: proximity analysis reveals spatial relationships between macrophage subtypes and metastasis-initiating cancer cells	57
Estrogen-related receptor alpha promotes thyroid tumor cell survival via a tumor subtype-specific regulation of target gene networks	56
N6-methyladenosine modified TGFB2 triggers lipid metabolism reprogramming to confer pancreatic ductal adenocarcinoma gemcitabine resistance	56
RHNO1: at the crossroads of DNA replication stress, DNA repair, and cancer	56
Single-cell profiling reveals altered immune landscape and impaired NK cell function in gastric cancer liver metastasis	56
EZH2 PROTACs target EZH2- and FOXM1-associated oncogenic nodes, suppressing breast cancer cell growth	55
Characterisation of APOBEC3B-Mediated RNA editing in breast cancer cells reveals regulatory roles of NEAT1 and MALAT1 lncRNAs	55
Alternative splicing of ALDOA confers tamoxifen resistance in breast cancer	55
ALDH1A3 is the switch that determines the balance of ALDH+ and CD24−CD44+ cancer stem cells, EMT-MET, and glucose metabolism in breast cancer	54
m6A-driven NAT10 translation facilitates fatty acid metabolic rewiring to suppress ferroptosis and promote ovarian tumorigenesis through enhancing ACOT7 mRNA acetylation	53
NSUN2 regulates Wnt signaling pathway depending on the m5C RNA modification to promote the progression of hepatocellular carcinoma	53
Breathing new insights into the role of mutant p53 in lung cancer	52
MAZ promotes tumor proliferation and immune evasion in lung adenocarcinoma	51
Hypoxia induced cellular and exosomal RPPH1 promotes breast cancer angiogenesis and metastasis through stabilizing the IGF2BP2/FGFR2 axis	51
Oncogenic potential of BEST4 in colorectal cancer via activation of PI3K/Akt signaling	50
Correction: Regucalcin promotes dormancy of prostate cancer	50
Correction: Targeting the HIF-1α-IGFBP2 axis therapeutically reduces IGF1-AKT signaling and blocks the growth and metastasis of relapsed anaplastic Wilms tumor	50
Overcoming acquired resistance to third-generation EGFR inhibitors by targeting activation of intrinsic apoptotic pathway through Mcl-1 inhibition, Bax activation, or both	49
HSP90 inhibitors induce GPNMB cell-surface expression by modulating lysosomal positioning and sensitize breast cancer cells to glembatumumab vedotin	48
Downregulation of LNMAS orchestrates partial EMT and immune escape from macrophage phagocytosis to promote lymph node metastasis of cervical cancer	47
The BCL-2 family member BOK promotes KRAS-driven lung cancer progression in a p53-dependent manner	47
LIGHT enhanced bispecific antibody armed T-cells to treat immunotherapy resistant colon cancer	46
TRIM32 promotes radioresistance by disrupting TC45-STAT3 interaction in triple-negative breast cancer	45
EMT-mediated regulation of CXCL1/5 for resistance to anti-EGFR therapy in colorectal cancer	45
De novo expression of gastrokines in pancreatic precursor lesions impede the development of pancreatic cancer	44
MiR-378a inhibits glucose metabolism by suppressing GLUT1 in prostate cancer	44
p53-NEIL1 co-abnormalities induce genomic instability and promote synthetic lethality with Chk1 inhibition in multiple myeloma having concomitant 17p13(del) and 1q21(gain)	44
GIPC2 interacts with Fzd7 to promote prostate cancer metastasis by activating WNT signaling	44
CRL2KLHDC3 mediates p14ARF N-terminal ubiquitylation degradation to promote non-small cell lung carcinoma progression	43
XAF1 destabilizes estrogen receptor α through the assembly of a BRCA1-mediated destruction complex and promotes estrogen-induced apoptosis	43
The keratin 17/YAP/IL6 axis contributes to E-cadherin loss and aggressiveness of diffuse gastric cancer	42
ANKFN1 plays both protumorigenic and metastatic roles in hepatocellular carcinoma	42
Thymidylate synthase O-GlcNAcylation: a molecular mechanism of 5-FU sensitization in colorectal cancer	42
TFAM downregulation promotes autophagy and ESCC survival through mtDNA stress-mediated STING pathway	42
Transcriptional regulation by MYC: an emerging new model	42
Correction: Loss of E-cadherin leads to Id2-dependent inhibition of cell cycle progression in metastatic lobular breast cancer	42

Dependence of PAX3-FOXO1 chromatin occupancy on ETS1 at important disease-promoting genes exposes new targetable vulnerability in Fusion-Positive Rhabdomyosarcoma	41
Pharmaco-proteogenomic profiling of pediatric diffuse midline glioma to inform future treatment strategies	41
Discoidin Domain Receptor 2 orchestrates melanoma resistance combining phenotype switching and proliferation	40
PTPRZ1 dephosphorylates and stabilizes RNF26 to reduce the efficacy of TKIs and PD-1 blockade in ccRCC	40
Therapeutic targeting of BAP1/ASXL3 sub-complex in ASCL1-dependent small cell lung cancer	40
MARK2 regulates chemotherapeutic responses through class IIa HDAC-YAP axis in pancreatic cancer	40
A comprehensive analysis of LMO2 pathogenic regulatory profile during T-lineage development and leukemic transformation	40
Transcription associated cyclin-dependent kinases as therapeutic targets for prostate cancer	40
CXCR4 and CXCR7 signaling promotes tumor progression and obesity-associated epithelial-mesenchymal transition in prostate cancer cells	39
EZH2 regulates a SETDB1/ΔNp63α axis via RUNX3 to drive a cancer stem cell phenotype in squamous cell carcinoma	39
AMPK-deficiency forces metformin-challenged cancer cells to switch from carbohydrate metabolism to ketogenesis to support energy metabolism	39
SCD5-dependent inhibition of SPARC secretion hampers metastatic spreading and favors host immunity in a TNBC murine model	39
IER2-induced senescence drives melanoma invasion through osteopontin	38
TMIGD1: Emerging functions of a tumor supressor and adhesion receptor	38
MCPIP1 inhibits Wnt/β-catenin signaling pathway activity and modulates epithelial-mesenchymal transition during clear cell renal cell carcinoma progression by targeting miRNAs	38
Notch signaling regulates a metabolic switch through inhibiting PGC-1α and mitochondrial biogenesis in dedifferentiated liposarcoma	38
Deciphering glioma epitranscriptome: focus on RNA modifications	38
Pathologists’ first opinions on barriers and facilitators of computational pathology adoption in oncological pathology: an international study	38
Liprins in oncogenic signaling and cancer cell adhesion	37
YAP governs cellular adaptation to perturbation of glutamine metabolism by regulating ATF4-mediated stress response	37
miR-151a-3p-rich small extracellular vesicles derived from gastric cancer accelerate liver metastasis via initiating a hepatic stemness-enhancing niche	37
ZNF545 loss promotes ribosome biogenesis and protein translation to initiate colorectal tumorigenesis in mice	37
Retraction Note: YAP1-induced MALAT1 promotes epithelial–mesenchymal transition and angiogenesis by sponging miR-126-5p in colorectal cancer	37
Commonalities and differences in the mutational signature and somatic driver mutation landscape across solid and hollow viscus organs	37
CRISPR screens identify cholesterol biosynthesis as a therapeutic target on stemness and drug resistance of colon cancer	37
C/ebpα represses the oncogenic Runx3–Myc axis in p53-deficient osteosarcoma development	37
MYC directly transactivates CR2/CD21, the receptor of the Epstein–Barr virus, enhancing the viral infection of Burkitt lymphoma cells	36
Clonal populations of a human TNBC model display significant functional heterogeneity and divergent growth dynamics in distinct contexts	36
GREB1 isoform 4 is specifically transcribed by MITF and required for melanoma proliferation	36
Polyploidy, EZH2 upregulation, and transformation in cytomegalovirus-infected human ovarian epithelial cells	36
FANCA deficiency promotes leukaemic progression by allowing the emergence of cells carrying oncogenic driver mutations	36
The cytotoxicity of γδT cells in non-small cell lung cancer mediated via coordination of the BCL-2 and AKT pathways	36
Correction: LACTB, a novel epigenetic silenced tumor suppressor, inhibits colorectal cancer progression by attenuating MDM2-mediated p53 ubiquitination and degradation	35
The extracellular-regulated protein kinase 5 (ERK5) enhances metastatic burden in triple-negative breast cancer through focal adhesion protein kinase (FAK)-mediated regulation of cell adhesion	35
Loss of DLX3 tumor suppressive function promotes progression of SCC through EGFR–ERBB2 pathway	35
CRISPR screens identify a novel combination treatment targeting BCL-XL and WNT signaling for KRAS/BRAF-mutated colorectal cancers	35
MRE11 promotes oral cancer progression through RUNX2/CXCR4/AKT/FOXA2 signaling in a nuclease-independent manner	35
Aberrant CREB1 activation in prostate cancer disrupts normal prostate luminal cell differentiation	35
Correction: SOX18 promotes gastric cancer metastasis through transactivating MCAM and CCL7	35
The role of polyamines in gastric cancer	35
Regulatory chromatin rewiring promotes metabolic switching during adaptation to oncogenic receptor tyrosine kinase inhibition	35
CPSF4 regulates circRNA formation and microRNA mediated gene silencing in hepatocellular carcinoma	34
YTHDF2 is a potential target of AML1/ETO-HIF1α loop-mediated cell proliferation in t(8;21) AML	34
Vaccinia-related kinase 2 drives pancreatic cancer progression by protecting Plk1 from Chfr-mediated degradation	34
WAPL induces cervical intraepithelial neoplasia modulated with estrogen signaling without HPV E6/E7	34
A micropeptide JunBP regulated by TGF-β promotes hepatocellular carcinoma metastasis	34
αSMA+ fibroblasts suppress Lgr5+ cancer stem cells and restrain colorectal cancer progression	34
Long non-coding RNA TILR constitutively represses TP53 and apoptosis in lung cancer	34
Combination of chemotherapy with BRAF inhibitors results in effective eradication of malignant melanoma by preventing ATM-dependent DNA repair	33
PCNA regulates primary metabolism by scaffolding metabolic enzymes	33
N4-acetylcytidine modification of lncRNA CTC-490G23.2 promotes cancer metastasis through interacting with PTBP1 to increase CD44 alternative splicing	33
Novel inhibition of AKR1C3 and androgen receptor axis by PTUPB synergizes enzalutamide treatment in advanced prostate cancer	33
Dual role of WNT5A in promoting endothelial differentiation of glioma stem cells and angiogenesis of glioma derived endothelial cells	33
The FLI portion of EWS/FLI contributes a transcriptional regulatory function that is distinct and separable from its DNA-binding function in Ewing sarcoma	33
DNAJA1 promotes cancer metastasis through interaction with mutant p53	32
RAF1 contributes to cell proliferation and STAT3 activation in colorectal cancer independently of microsatellite and KRAS status	32
EWI2 and its relatives in Tetraspanin-enriched membrane domains regulate malignancy	32
Correction to: A combination of novel NSC small molecule inhibitor along with doxorubicin inhibits proliferation of triple-negative breast cancer through metabolic reprogramming	32
Applicability of liquid biopsies to represent the mutational profile of tumor tissue from different cancer entities	32
Sirt1 deficiency upregulates glutathione metabolism to prevent hepatocellular carcinoma initiation in mice	32
The hTERT-p50 homodimer inhibits PLEKHA7 expression to promote gastric cancer invasion and metastasis	32
Glucose-mediated N-glycosylation of RPTPα affects its subcellular localization and Src activation	32
Correction to: SFRP2 induces a mesenchymal subtype transition by suppression of SOX2 in glioblastoma	32
NUDT22 promotes cancer growth through pyrimidine salvage	32
Whole-transcriptome and proteome analyses identify key differentially expressed mRNAs, miRNAs, lncRNAs and circRNAs associated with HCC	32
Blocking LBH expression causes replication stress and sensitizes triple-negative breast cancer cells to ATR inhibitor treatment	31
The Hippo-YAP signaling pathway drives CD24-mediated immune evasion in esophageal squamous cell carcinoma via macrophage phagocytosis	31
DLGAP5 triggers proliferation and metastasis of bladder cancer by stabilizing E2F1 via USP11	31
Correction: Inhibition of the transcriptional kinase CDK7 overcomes therapeutic resistance in HER2-positive breast cancers	31
Overcoming resistance to programmed cell death protein 1 (PD-1) blockade with allogeneic invariant natural killer T-cells (iNKT)	31
Glucocorticoid treatment influences prostate cancer cell growth and the tumor microenvironment via altered glucocorticoid receptor signaling in prostate fibroblasts	31
METTL3-mediated N6-methyladenosine modification of STAT5A promotes gastric cancer progression by regulating KLF4	31
Dual network analysis of transcriptome data for discovery of new therapeutic targets in non-small cell lung cancer	31
ERK hyperactivation serves as a unified mechanism of escape in intrinsic and acquired CDK4/6 inhibitor resistance in acral lentiginous melanoma	31
Safety and efficacy of prophylactic and therapeutic vaccine based on live-attenuated Listeria monocytogenes in hepatobiliary cancers	30
scRNA‐seq reveals the landscape of immune repertoire of PBMNCs in iMCD	30
Notch3-regulated microRNAs impair CXCR4-dependent maturation of thymocytes allowing maintenance and progression of T-ALL	30
MZF1 mediates oncogene-induced senescence by promoting the transcription of p16INK4A	30
Alpelisib and fulvestrant in PIK3CA-mutated hormone receptor-positive HER2-negative advanced breast cancer included in the French early access program	30
BTLA+CD200+ B cells dictate the divergent immune landscape and immunotherapeutic resistance in metastatic vs. primary pancreatic cancer	30

Regulation of cancer stem cell activity by thyroid hormone receptor β	30
IGF-1R is a molecular determinant for response to p53 reactivation therapy in conjunctival melanoma	30
KRAS phosphorylation regulates cell polarization and tumorigenic properties in colorectal cancer	30
EZH2-Myc driven glioblastoma elicited by cytomegalovirus infection of human astrocytes	30
PTEN-regulated PI3K-p110 and AKT isoform plasticity controls metastatic prostate cancer progression	30
Glioma immunotherapy enhancement and CD8-specific sialic acid cleavage by isocitrate dehydrogenase (IDH)-1	30
NFκB activation by hypoxic small extracellular vesicles drives oncogenic reprogramming in a breast cancer microenvironment	29
Correction to: NF-κB mediates radio-sensitization by the PARP-1 inhibitor, AG-014699	29
Correction: Nuclear translocation of IGF-1R via p150Glued and an importin-β/RanBP2-dependent pathway in cancer cells	29
Correction: LncFZD6 initiates Wnt/β-catenin and liver TIC self-renewal through BRG1-mediated FZD6 transcriptional activation	29
Correction: CEACAM1 impedes thyroid cancer growth but promotes invasiveness: a putative mechanism for early metastases	29
Correction to: Fhit modulation of the Akt-survivin pathway in lung cancer cells: Fhit-tyrosine 114 (Y114) is essential	29
Correction: Interaction between STAT3 and GLI1/tGLI1 oncogenic transcription factors promotes the aggressiveness of triple-negative breast cancers and HER2-enriched breast cancer	29
Correction: CUL4B promotes gastric cancer invasion and metastasis-involvement of upregulation of HER2	28
RNA binding protein RBMS3 is a common EMT effector that modulates triple-negative breast cancer progression via stabilizing PRRX1 mRNA	28
Correction: S100A3 a partner protein regulating the stability/activity of RARα and PML-RARα in cellular models of breast/lung cancer and acute myeloid leukemia	28
Therapeutic implication of oxidative stress-induced growth inhibitor 1 (OSGIN1) in cancer	28
Correction: Therapeutic targeting of necroptosis by Smac mimetic bypasses apoptosis resistance in acute myeloid leukemia cells	28
Oncogenic long intervening noncoding RNA Linc00284 promotes c-Met expression by sponging miR-27a in colorectal cancer	28
Oncogenic RAS promotes leukemic transformation of CUX1-deficient cells	28
Correction to: p14ARF inhibits the growth of lung adenocarcinoma cells harbouring an EGFR L858R mutation by activating a STAT3-dependent pro-apoptotic signalling pathway	28
A synergistic partnership between IL-33/ST2 and Wnt pathway through Bcl-xL drives gastric cancer stemness and metastasis	28
Correction: Targeting ErbB-2 nuclear localization and function inhibits breast cancer growth and overcomes trastuzumab resistance	28
Activation of invasion by oncogenic reprogramming of cholesterol metabolism via increased NPC1 expression and macropinocytosis	28
RBM39 promotes hepatocarcinogenesis by regulating RFX1’s alternative splicing and subsequent activation of integrin signaling pathway	28
Circular RNA EIF3I promotes papillary thyroid cancer progression by interacting with AUF1 to increase Cyclin D1 production	28
CircME1 promotes aerobic glycolysis and sunitinib resistance of clear cell renal cell carcinoma through cis-regulation of ME1	28
Correction: Activation of ErbB-2 via a hierarchical interaction between ErbB-2 and type I insulin-like growth factor receptor in mammary tumor cells	28
Identification of novel germline mutations in FUT7 and EXT1 linked with hereditary multiple exostoses	28
Correction: Hsa_circ_0001361 promotes bladder cancer invasion and metastasis through miR-491-5p/MMP9 axis	28
SMAD4 is critical in suppression of BRAF-V600E serrated tumorigenesis	28
NRF2 has a splicing regulatory function involving the survival of motor neuron (SMN) in non-small cell lung cancer	28
Regulator of calcineurin 1 gene isoform 4 in pancreatic ductal adenocarcinoma regulates the progression of tumor cells	27
NK and NKT cells have distinct properties and functions in cancer	27
SUMOylation inhibition potentiates the glucocorticoid receptor to program growth arrest of acute lymphoblastic leukemia cells	27
Linear ubiquitination of PTEN impairs its function to promote prostate cancer progression	27
Tumor-associated macrophages promote PD-L1 expression in tumor cells by regulating PKM2 nuclear translocation in pancreatic ductal adenocarcinoma	27
Copper ionophore elesclomol selectively targets GNAQ/11-mutant uveal melanoma	27
H3K9me3 represses G6PD expression to suppress the pentose phosphate pathway and ROS production to promote human mesothelioma growth	27
The roles of intratumour heterogeneity in the biology and treatment of pancreatic ductal adenocarcinoma	27
Synthetic lethal kinases in Ras/p53 mutant squamous cell carcinoma	27
PRAME induces genomic instability in uveal melanoma	27
RING-finger protein 6 promotes colorectal tumorigenesis by transcriptionally activating SF3B2	26
FBXO28 suppresses liver cancer invasion and metastasis by promoting PKA-dependent SNAI2 degradation	26
Genetic modifiers regulating DNA replication and double-strand break repair are associated with differences in mammary tumors in mouse models of Li-Fraumeni syndrome	26
LIMK2 promotes melanoma tumor growth and metastasis through G3BP1-ESM1 pathway-mediated apoptosis inhibition	26
Synergistic effects of combined BET and FAK inhibition against Vestibular Schwannomas in NF2-related Schwannomatosis	26
Emergence of β1 integrin-deficient breast tumours from dormancy involves both inactivation of p53 and generation of a permissive tumour microenvironment	26
Regulation of Src tumor activity by its N-terminal intrinsically disordered region	26
TRIM59 is suppressed by androgen receptor and acts to promote lineage plasticity and treatment-induced neuroendocrine differentiation in prostate cancer	26
VPS35 promotes gastric cancer progression through integrin/FAK/SRC signalling-mediated IL-6/STAT3 pathway activation in a YAP-dependent manner	26
Autophagy regulates the cancer stem cell phenotype of head and neck squamous cell carcinoma through the noncanonical FOXO3/SOX2 axis	26
Viral and cellular oncogenes promote immune evasion	26
Breast cancer stem cell-derived exosomal lnc-PDGFD induces fibroblast-niche formation and promotes lung metastasis	26
SKAP2 suppresses inflammation-mediated tumorigenesis by regulating SHP-1 and SHP-2	26
Dual inhibition of ATR and DNA-PKcs radiosensitizes ATM-mutant prostate cancer	25
New perspectives for targeting therapy in ALK-positive human cancers	25
Spatiotemporal view of malignant histogenesis and macroevolution via formation of polyploid giant cancer cells	25
Menin inhibition suppresses castration-resistant prostate cancer and enhances chemosensitivity	25
The nerve cells in gastrointestinal cancers: from molecular mechanisms to clinical intervention	25
A prismatic view of the epigenetic-metabolic regulatory axis in breast cancer therapy resistance	25
A micropeptide XBP1SBM encoded by lncRNA promotes angiogenesis and metastasis of TNBC via XBP1s pathway	25
A noncanonical E3 ubiquitin ligase RNF41-mediated MYO1C stability promotes prostate cancer metastasis by inducing actin remodeling	25
Serine-arginine protein kinase 1 (SRPK1) promotes EGFR-TKI resistance by enhancing GSK3β Ser9 autophosphorylation independent of its kinase activity in non-small-cell lung cancer	25
DHODH inhibition represents a therapeutic strategy and improves abiraterone treatment in castration-resistant prostate cancer	25
Monitoring the 5′UTR landscape reveals isoform switches to drive translational efficiencies in cancer	25
PSMD14 stabilizes estrogen signaling and facilitates breast cancer progression via deubiquitinating ERα	25
Targeting STING elicits GSDMD-dependent pyroptosis and boosts anti-tumor immunity in renal cell carcinoma	25
ST6GAL1 inhibits metastasis of hepatocellular carcinoma via modulating sialylation of MCAM on cell surface	25
TWIST1 is a critical downstream target of the HGF/MET pathway and is required for MET driven acquired resistance in oncogene driven lung cancer	25
Synthetic lethal combination of CHK1 and WEE1 inhibition for treatment of castration-resistant prostate cancer	24
TKT-PARP1 axis induces radioresistance by promoting DNA double-strand break repair in hepatocellular carcinoma	24
IGF1R acts as a cancer-promoting factor in the tumor microenvironment facilitating lung metastasis implantation and progression	24
Fermitin family member 2 promotes melanoma progression by enhancing the binding of p-α-Pix to Rac1 to activate the MAPK pathway	24
MAD2 activates IGF1R/PI3K/AKT pathway and promotes cholangiocarcinoma progression by interfering USP44/LIMA1 complex	24
KLF5 regulates actin remodeling to enhance the metastasis of nasopharyngeal carcinoma	24
Novel thrombospondin-1 transcript exhibits distinctive expression and activity in thyroid tumorigenesis	24
The role of R-spondin proteins in cancer biology	24
Alleviating hypoxia to improve cancer immunotherapy	24
Brg1 controls stemness and metastasis of pancreatic cancer through regulating hypoxia pathway	24
Nup54-induced CARM1 nuclear importation promotes gastric cancer cell proliferation and tumorigenesis through transcriptional activation and methylation of Notch2	24
SUMOylation facilitates the stability of BCR-ABL to promote chronic myeloid leukemia progression	24
The Dickkopf1 and FOXM1 positive feedback loop promotes tumor growth in pancreatic and esophageal cancers	24
Structure and function of MuvB complexes	24
Human CSPG4-targeting CAR-macrophages inhibit melanoma growth	23
Correction to: KSR1 regulates BRCA1 degradation and inhibits breast cancer growth	23
LGALS9B stabilizes EEF1D protein and activates the PI3K/AKT signaling pathway to promote gastric cancer occurrence and metastasis	23
A urine DNA methylation assay for early detection of renal cancer	23
The urothelial gene regulatory network: understanding biology to improve bladder cancer management	23
Delactylase effects of SIRT1 on a positive feedback loop involving the H19-glycolysis-histone lactylation in gastric cancer	23
Dexamethasone suppresses immune evasion by inducing GR/STAT3 mediated downregulation of PD-L1 and IDO1 pathways	23
ZEB2 facilitates peritoneal metastasis by regulating the invasiveness and tumorigenesis of cancer stem-like cells in high-grade serous ovarian cancers	23
Editorial Expression of Concern: Role of BRCA1 in heat shock response	23
Molecular characterization stratifies VQ myeloma cells into two clusters with distinct risk signatures and drug responses	23
N6-methyadenosine-modified YWHAE mRNA promotes proliferation and inhibits ferroptosis in hepatoblastoma by mediating SLC7A11 expression	23