OOIR: Observatory of International Research

Papers

(The H4-Index of Phytotherapy Research is 47. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-05-01 to 2024-05-01.)

Article	Citations
Potential effects of curcumin in the treatment of COVID‐19 infection	218
A role for quercetin in coronavirus disease 2019 (COVID‐19)	182
Quercetin and its derivates as antiviral potentials: A comprehensive review	172
Naringenin, a flavanone with antiviral and anti‐inflammatory effects: A promising treatment strategy against COVID‐19	160
Piperine: A review of its biological effects	159
Quercetin and metabolic syndrome: A review	148
Potential roles of medicinal plants for the treatment of viral diseases focusing on COVID‐19: A review	148
Therapeutic benefits of rutin and its nanoformulations	126
Natural products for COVID‐19 prevention and treatment regarding to previous coronavirus infections and novel studies	123
Natural products: A lead for drug discovery and development	107
Molecular mechanisms of anticancer effect of rutin	99
Curcumin and its derivatives in cancer therapy: Potentiating antitumor activity of cisplatin and reducing side effects	95
Ginger (Zingiber officinale Rosc.) and its bioactive components are potential resources for health beneficial agents	93
Beneficial effects of Trichoderma secondary metabolites on crops	84
Oral nano‐curcumin formulation efficacy in management of mild to moderate hospitalized coronavirus disease‐19 patients: An open label nonrandomized clinical trial	81
Botanical drugs and supplements affecting the immune response in the time of COVID‐19: Implications for research and clinical practice	79
In silico and in vitro evaluation of kaempferol as a potential inhibitor of the SARS‐CoV‐2 main protease (3CLpro)	75
Bee products as a source of promising therapeutic and chemoprophylaxis strategies against COVID‐19 (SARS‐CoV‐2)	74
Natural compounds against doxorubicin‐induced cardiotoxicity: A review on the involvement of Nrf2/ARE signaling pathway	74
Resveratrol inhibits the replication of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) in cultured Vero cells	73
Efficacy and safety of Xiyanping injection in the treatment of COVID‐19: A multicenter, prospective, open‐label and randomized controlled trial	68
Food as medicine: A possible preventive measure against coronavirus disease (COVID‐19)	67
Biological and pharmacological effects and nutritional impact of phytosterols: A comprehensive review	67
Effects of essential oils on central nervous system: Focus on mental health	66
The review of alpha‐linolenic acid: Sources, metabolism, and pharmacology	66

Anticancer activity of the plant flavonoid luteolin against preclinical models of various cancers and insights on different signalling mechanisms modulated	64
The effect of green tea supplementation on obesity: A systematic review and dose–response meta‐analysis of randomized controlled trials	64
Ficus plants: State of the art from a phytochemical, pharmacological, and toxicological perspective	62
Diabetes and plant‐derived natural products: From ethnopharmacological approaches to their potential for modern drug discovery and development	62
Anti‐inflammatory effect of Rhein on ulcerative colitis via inhibiting PI3K/Akt/mTOR signaling pathway and regulating gut microbiota	61
Curcumin nanoformulations: Beneficial nanomedicine against cancer	60
A review of therapeutic potentials of turmeric (Curcuma longa) and its active constituent, curcumin, on inflammatory disorders, pain, and their related patents	60
Ganoderma lucidum (Reishi) an edible mushroom; a comprehensive and critical review of its nutritional, cosmeceutical, mycochemical, pharmacological, clinical, and toxicological properties	60
Natural products as home‐based prophylactic and symptom management agents in the setting of COVID‐19	58
Glycyrrhizin: An old weapon against a novel coronavirus	58
Wogonin and its analogs for the prevention and treatment of cancer: A systematic review	57
Astaxanthin, COVID‐19 and immune response: Focus on oxidative stress, apoptosis and autophagy	55
Spices and herbs: Potential antiviral preventives and immunity boosters during COVID‐19	54
Curcumin supplementation in pediatric patients: A systematic review of current clinical evidence	54
A triple‐blind, placebo‐controlled, randomized clinical trial to evaluate the effect of curcumin‐containing nanomicelles on cellular immune responses subtypes and clinical outcome in COVID‐	53
A comprehensive review of the therapeutic potential of α‐arbutin	52
Sulforaphane: A review of its therapeutic potentials, advances in its nanodelivery, recent patents, and clinical trials	51
Quercetin as a protective agent for liver diseases: A comprehensive descriptive review of the molecular mechanism	50
Effects of phytochemicals on macrophage cholesterol efflux capacity: Impact on atherosclerosis	48
Effects of quercetin supplementation on inflammatory factors and quality of life in post‐myocardial infarction patients: A double blind, placebo‐controlled, randomized clinical trial	48
Curcumin downregulates the PI3K–AKT–mTOR pathway and inhibits growth and progression in head and neck cancer cells	48
Kaempferol exerts a neuroprotective effect to reduce neuropathic pain through TLR4/NF‐ĸB signaling pathway	48
The role of medicinal products in the treatment of inflammatory bowel diseases (IBD) through inhibition of TLR4/NF‐kappaB pathway	47
Bacosides from Bacopa monnieri extract: An overview of the effects on neurological disorders	47
Oridonin induces ferroptosis by inhibiting gamma‐glutamyl cycle in TE1 cells	47
Anti‐inflammatory effects of cordycepin: A review	47
Emodin alleviates LPS‐induced myocardial injury through inhibition of NLRP3 inflammasome activation	47
New insights into the role of the Nrf2 signaling pathway in green tea catechin applications	47
Phytochemical constituents, biological activities, and health‐promoting effects of the genusOriganum	47
Andrographolide: A review of its pharmacology, pharmacokinetics, toxicity and clinical trials and pharmaceutical researches	47
Bio‐actives of betel leaf (Piper betle L.): A comprehensive review on extraction, isolation, characterization, and biological activity	47