OOIR: Observatory of International Research

Papers

(The H4-Index of Phytotherapy Research is 45. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-10-01 to 2025-10-01.)

Article	Citations
Zingibroside R1 Isolated From Achyranthes bidentata Blume Ameliorates LPS/D‐GalN‐Induced Liver Injury by Regulating Succinic Acid Metabolism via the	319
Unleashing the Therapeutic Power of Natural Alkaloids in Triple‐Negative Breast Cancer: State‐of‐the‐Art Advances and Future Directions	155
Harnessing Essential Oils for Acetylcholinesterase Inhibition: A Literature Review	150
Targeting Mitochondrial Dysfunction by Natural Products for the Treatment of Diabetic Kidney Disease	131
Curcumin as a therapeutic agent in cancer therapy: Focusing on its modulatory effects on circularRNAs	116
Vegetable‐derived indole enhances the melanoma‐treating efficacy of chemotherapeutics	116
RETRACTION: Epigallocatechin‐3‐Gallate Enhances Differentiation of Acute Promyelocytic Leukemia Cells via Inhibition of PML‐RARα and HDAC1	109
Phase III randomized clinical trial of BV‐4051, an Ayurvedic polyherbal formulation in moderate SARS‐CoV‐2 infections and its impact on inflammatory biomarkers	108
Polysaccharides (pectin, mucilage, and fructan inulin) and their fermented products: A critical analysis of their biochemical, gut interactions, and biological functions as antidiabetic agents	102
The influence of propolis plus Hyoscyamus niger L. against COVID‐19: A phase II, multicenter, placebo‐controlled, randomized trial	97
The effect of propolis supplementation on cardiovascular risk factors in women with rheumatoid arthritis: A double‐blind, placebo, controlled randomized clinical trial	94
Phytochemicals targeting ferroptosis in cardiovascular diseases: Recent advances and therapeutic perspectives	92
Maltol mitigates cisplatin‐evoked cardiotoxicity via inhibiting the PI3K/Akt signaling pathway in rodents in vivo and in vitro	90
Dietary plants for oral cancer prevention and therapy: A review of preclinical and clinical studies	88
Co‐administration of sub‐effective doses of the constituents of Crocus sativus L. crocins with those of the antipsychotics clozapine and risperidone counteract memory deficits caused by blockad	85
Effects of different natural products in patients with non‐alcoholic fatty liver disease—A network meta‐analysis of randomized controlled trials	77
Effects of gypenoside L‐containingGynostemma pentaphyllumextract on fatigue and physical performance: A double‐blind, placebo‐controlled, randomized trial	75
Phytoncides could potentially inhibit the spike protein of SARS‐CoV‐2 variants	73
Antiplatelet effect of ginkgo diterpene lactone meglumine injection in acute ischemic stroke: A randomized, double‐blind, placebo‐controlled clinical trial	72
Saponin monomers: Potential candidates for the treatment of type 2 diabetes mellitus and its complications	71
Polydatin as a therapeutic alternative for central nervous system disorders: A systematic review of animal studies	71
Safety assessment and adverse drug reaction reporting of tea tree oil (Melaleuca aetheroleum)	66
Astragaloside IV Alleviates Acute Hepatic Injury by Regulating Macrophage Polarization and Pyroptosis via Activation of the AMPK/SIRT1 Signaling Pathway	64
Bryodulcosigenin attenuates bleomycin‐induced pulmonary fibrosis via inhibiting AMPK‐mediated mesenchymal epithelial transition and oxidative stress	62
Natural compounds as obesity pharmacotherapies	61

Piperine Improves DSS‐Induced Colitis in Mice via Inhibition of Inflammation and Modulation of Gut Microbiota	60
Astragalin Inhibits Oxidative Stress‐Induced Pyroptosis and Apoptosis in Mouse Models of Renal Ischemia/Reperfusion Injury by Activating the SIRT1/Nrf2 Pathway	57
Anti‐Warburg effect via generation of ROS and inhibition of PKM2/β‐catenin mediates apoptosis of lambertianic acid in prostate cancer cells	57
Efficacy of frankincense‐based herbal product in urinary incontinence: A randomized, double‐blind, placebo‐ and active‐controlled clinical trial	55
Modulation of miRNAs by Phytochemicals in Cerebral Ischemia: A Systematic Review of In Vitro and In Vivo Studies	52
Preclinical studies of the antitumor effect of curcumin‐loaded polymeric nanocapsules: A systematic review and meta‐analysis	52
Harnessing the Potential of Carotenoids for Cancer Therapy: An Integrated Machine Learning and MST Based Approach	52
Pharmacovigilance of unlicensed cannabidiol in European countries	51
Ethanol extract of Pueraria lobata improve acute myocardial infarction in rats via regulating gut microbiota and bile acid metabolism	51
Curculigoside rescues hippocampal synaptic deficits elicited by PTSD through activating cAMP‐PKA signaling	50
Issue Information	48
Xanthohumol Regulates Mitophagy in Osteosarcoma Cells via AMPK‐ULK1‐FUNDC1 Signaling Pathway	48
Schisandra B, a representative lignan from Schisandra chinensis, improves cisplatin‐induced toxicity: An in vitro study	47
Cover Image	47
The effects of spirulina intake on clinical and metabolic parameters in Alzheimer's disease: A randomized, double‐blind, controlled trial	47
Ellagitannin Component Punicalin Ameliorates Cognitive Dysfunction, Oxidative Stress, and Neuroinflammation via the Inhibition of cGAS‐STING Signaling in the Brain of an Aging Mo	46
Correction to “Antiinflammatory Effects and Chemical Constituents of Veronicastrum axillare”	45
	45
	45
The alleviative effect of flavonol‐type Nrf2 activator rhamnazin from Physalis alkekengi L. var. franchetii (Mast.) Makino on pulmonary disorders	45