Phytotherapy Research

Article	Citations
Curcumin as a therapeutic agent in cancer therapy: Focusing on its modulatory effects on circularRNAs	309
Vegetable‐derived indole enhances the melanoma‐treating efficacy of chemotherapeutics	181
RETRACTION: Epigallocatechin‐3‐Gallate Enhances Differentiation of Acute Promyelocytic Leukemia Cells via Inhibition of PML‐RARα and HDAC1	152
Co‐administration of sub‐effective doses of the constituents of Crocus sativus L. crocins with those of the antipsychotics clozapine and risperidone counteract memory deficits caused by blockad	145
Phytochemicals targeting ferroptosis in cardiovascular diseases: Recent advances and therapeutic perspectives	128
Evaluation of the effect of Lepidium meyenii Walpers in infertile patients: A randomized, double‐blind, placebo‐controlled trial	115
Effects of different natural products in patients with non‐alcoholic fatty liver disease—A network meta‐analysis of randomized controlled trials	111
Effects of gypenoside L‐containingGynostemma pentaphyllumextract on fatigue and physical performance: A double‐blind, placebo‐controlled, randomized trial	104
Safety assessment and adverse drug reaction reporting of tea tree oil (Melaleuca aetheroleum)	104
Schisandra B, a representative lignan from Schisandra chinensis, improves cisplatin‐induced toxicity: An in vitro study	103
Phytoncides could potentially inhibit the spike protein of SARS‐CoV‐2 variants	97
Antiplatelet effect of ginkgo diterpene lactone meglumine injection in acute ischemic stroke: A randomized, double‐blind, placebo‐controlled clinical trial	94
Maltol mitigates cisplatin‐evoked cardiotoxicity via inhibiting the PI3K/Akt signaling pathway in rodents in vivo and in vitro	89
Dietary plants for oral cancer prevention and therapy: A review of preclinical and clinical studies	87
Issue Information	86
Xanthohumol Regulates Mitophagy in Osteosarcoma Cells via AMPK‐ULK1‐FUNDC1 Signaling Pathway	82
Cover Image	79
Preclinical studies of the antitumor effect of curcumin‐loaded polymeric nanocapsules: A systematic review and meta‐analysis	72
Ethanol extract of Pueraria lobata improve acute myocardial infarction in rats via regulating gut microbiota and bile acid metabolism	71
Curculigoside rescues hippocampal synaptic deficits elicited by PTSD through activating cAMP‐PKA signaling	71
Pharmacovigilance of unlicensed cannabidiol in European countries	71
Targeting Mitochondrial Dysfunction by Natural Products for the Treatment of Diabetic Kidney Disease	69
Bryodulcosigenin attenuates bleomycin‐induced pulmonary fibrosis via inhibiting AMPK‐mediated mesenchymal epithelial transition and oxidative stress	63
Harnessing Essential Oils for Acetylcholinesterase Inhibition: A Literature Review	63
Harnessing the Potential of Carotenoids for Cancer Therapy: An Integrated Machine Learning and MST Based Approach	63

Polysaccharides (pectin, mucilage, and fructan inulin) and their fermented products: A critical analysis of their biochemical, gut interactions, and biological functions as antidiabetic agents	62
Natural compounds as obesity pharmacotherapies	58
Phase III randomized clinical trial of BV‐4051, an Ayurvedic polyherbal formulation in moderate SARS‐CoV‐2 infections and its impact on inflammatory biomarkers	57
The influence of propolis plus Hyoscyamus niger L. against COVID‐19: A phase II, multicenter, placebo‐controlled, randomized trial	56
Zingibroside R1 Isolated From Achyranthes bidentata Blume Ameliorates LPS/D‐GalN‐Induced Liver Injury by Regulating Succinic Acid Metabolism via the	54
Piperine Improves DSS‐Induced Colitis in Mice via Inhibition of Inflammation and Modulation of Gut Microbiota	54
Unleashing the Therapeutic Power of Natural Alkaloids in Triple‐Negative Breast Cancer: State‐of‐the‐Art Advances and Future Directions	50
Polydatin as a therapeutic alternative for central nervous system disorders: A systematic review of animal studies	50
Ellagitannin Component Punicalin Ameliorates Cognitive Dysfunction, Oxidative Stress, and Neuroinflammation via the Inhibition of cGAS‐STING Signaling in the Brain of an Aging Mo	50
The effects of spirulina intake on clinical and metabolic parameters in Alzheimer's disease: A randomized, double‐blind, controlled trial	50
Astragaloside IV Alleviates Acute Hepatic Injury by Regulating Macrophage Polarization and Pyroptosis via Activation of the AMPK/SIRT1 Signaling Pathway	49
Anti‐Warburg effect via generation of ROS and inhibition of PKM2/β‐catenin mediates apoptosis of lambertianic acid in prostate cancer cells	49
The effect of propolis supplementation on cardiovascular risk factors in women with rheumatoid arthritis: A double‐blind, placebo, controlled randomized clinical trial	48
	47
Efficacy of frankincense‐based herbal product in urinary incontinence: A randomized, double‐blind, placebo‐ and active‐controlled clinical trial	47
Saponin monomers: Potential candidates for the treatment of type 2 diabetes mellitus and its complications	47
The alleviative effect of flavonol‐type Nrf2 activator rhamnazin from Physalis alkekengi L. var. franchetii (Mast.) Makino on pulmonary disorders	45
	45
Urolithin A alleviates acute kidney injury induced by renal ischemia reperfusion through the p62‐Keap1‐Nrf2 signaling pathway	44
Substantial Effects of Carotenoids on Skin Health: A Mechanistic Perspective	44
Cardiovascular benefits of Eruca sativa mill. Defatted seed meal extract: Potential role of hydrogen sulfide	44
Upregulation of key factors of viral entry of corona‐ and influenza viruses upon TLR3‐signaling in cells from the respiratory tract and clinical treatment options by 1,8‐Cineol	44
Mechanisms and Potential of Antitumor Therapy With Natural Products Regulating Non‐Coding RNAs	44
Asiatic acid inhibits angiogenesis and vascular permeability through the VEGF/VEGFR2 signaling pathway to inhibit the growth and metastasis of breast cancer in mice	43
SH‐PRO extract alleviates benign prostatic hyperplasia via ROS‐mediated activation of PARP/caspase 3 and inhibition of FOXO3a/AR/PSA s	43
Brazilian red propolis exerts a cytotoxic action against prostate cancer cells and upregulates human monocyte functions	42
A grape (Vitis vinifera L.) pomace water extract modulates inflammatory and immune response in SW‐480 cells and isolated mouse colon	42
Mitochondrial‐targeted curcumin inhibits T‐cell activation via Nrf2 and inhibits graft‐versus‐host‐disease in a mouse model	42
Costunolide protects against alcohol‐induced liver injury by regulating gut microbiota, oxidative stress and attenuating inflammation in vivo and in vitro	42
Effect of curcumin on C‐reactive protein as a biomarker of systemic inflammation: An updated meta‐analysis of randomized controlled trials	41
Immunostimulant plant proteins: Potential candidates as vaccine adjuvants	41
Issue Information	41
Xanthohumol Alleviates Inflammatory Bowel Disease‐Associated Osteoporosis via Regulating Gut Microbial Metabolites	41
Therapeutic Potential of Chinese Herbal Medicine and Underlying Mechanism for the Treatment of Myocardial Infarction	40
Ouratein D, a Biflavanone From Ouratea spectabilis, Alleviates Betacoronavirus Infection by Mitigating Inflammation, Lung Damage and Viral Replication	40
Jatrorrhizine alleviates cytokine storm secondary lung injury via regulating CD39‐dominant purinergic braking and downstream NLRP3 inflammasome	40
Nootkatone alleviates rotenone‐induced Parkinson's disease symptoms through activation of the PI3K/Akt signaling pathway	39
Effects of artichoke leaf extract supplementation or artichoke juice consumption on lipid profile: A systematic review and dose–response meta‐analysis of randomized controlled trials	39
Fangchinoline abrogates growth and survival of hepatocellular carcinoma by negative regulation of c‐met/HGF and its associated downstream signaling pathways	39
The effects of Garcinia cambogia (hydroxycitric acid) on lipid profile: A systematic review and meta‐analysis of randomized controlled trials	39
4′‐Hydroxychalcone Induces Ferroptosis in Glioblastoma Through the xCT/GSH/GPX4 Axis Under the Regulation of the AKT/mTORC1/4EBP1 Path	38
Trilobatin promotes angiogenesis after cerebral ischemia–reperfusion injury via SIRT7/VEGFA signaling pathway in rats	38
Exploring the therapeutic implications of natural compounds modulating apoptosis in vascular dementia	38
Morus alba L. water extract changes gut microbiota and fecal metabolome in mice induced by high‐fat and high‐sucrose diet plus low‐dose streptozotocin	38
Bavachinin selectively modulates PPAR γ and maintains bone homeostasis in Type 2 Diabetes	37
Issue Information	36
Therapeutic effect of Eleutherococcus senticosus (Rupr. & Maxim.) Maxim. leaves on ischemic stroke via the microbiota–gut–brain axis	36
Issue Information	36
Issue Information	36
Hyperoside prevents doxorubicin‐induced cardiotoxicity by inhibiting NOXs/ROS/NLRP3 inflammasome signaling pathway	36

The effects of lycopene supplementation on insulin‐like growth factor‐1 and insulin‐like growth factor binding proteins: A systematic review of randomized controlled trials	35
Effect of sumac powder on clinical symptoms, hyperandrogenism, inflammation, blood glucose, lipid profiles in women with polycystic ovary syndrome: A double‐blind randomized clinical trial	35
Curcumin supplementation as a complementary and alternative medicine for COVID‐19 patients	35
	35
Lotusine ameliorates propionic acid‐induced autism spectrum disorder‐like behavior in mice by activating D1 dopamine receptor in medial prefrontal cortex	35
Natural products targeting macroautophagy signaling in hepatocellular carcinoma therapy: Recent evidence and perspectives	35
An exploratory double‐blind, randomized, placebo‐controlled study to assess the efficacy of CitruSlim on body composition and lipid parameters in obese individuals	35
Phytocompounds and COVID‐19: Two years of knowledge	34
A randomized, double‐blind, placebo‐controlled study of Cistanche tubulosa and Ginkgo biloba extracts for the improvement of cognitive function in middle‐aged and elderly people	34
Is the mushroom Meripilus giganteus a potential cancer chemopreventive agent?	34
Gut microbiota, bile acids, and nature compounds	34
Natural products in suppressing glioma progression: A focus on the role of microRNAs	34
Trifolirhizin reduces osteoclast formation and prevents inflammatory osteolysis by inhibiting RANKL‐induced activation of NF‐κB and MAPK signaling pathways and ROS	33
Astragaloside IV ameliorates radiation‐induced nerve cell damage by activating the BDNF/TrkB signaling pathway	33
miRNA, phytometabolites and disease: Connecting the dots	33
Efficacy of herbal treatments for functional dyspepsia: A systematic review and meta‐analysis of randomized clinical trials	33
Acetylshikonin Derived From Arnebia euchroma (Royle) Johnst Kills Multidrug‐Resistant Gram‐Positive Pathogens In Vitro and In Vivo	33
Effect of walnut consumption on markers of endothelial function in adults: A systematic review and meta‐analysis of randomized controlled trials	32
The effect of saffron (Crocus sativus L.) on glycemia, lipid profile, and antioxidant status in patients with type‐2 diabetes mellitus: A randomized placebo‐controlled trial	32
Effects of ginseng consumption on the biomarkers of oxidative stress: A systematic review and meta‐analysis	32
Therapeutic considerations of bioactive compounds in Alzheimer's disease and Parkinson's disease: Dissecting the molecular pathways	32
Cornuside, by regulating the AGEs‐RAGE‐IκBα‐ERK1/2 signaling pathway, ameliorates cognitive impairment associated with brain aging	32
Ginkgo Flavone Aglycone Ameliorates Atherosclerosis via Inhibiting Endothelial Pyroptosis by Activating the Nrf2 Pathway	32
Helichrysum stoechas (L.) Moench reduces body weight gain and modulates mood disorders via inhibition of silent information regulator 1 (SIRT1) by arzanol	31
Curcumin and nano‐curcumin applications in psychiatric disorders	31
Formononetin attenuates cigarette smoke‐induced COPD in mice by suppressing inflammation, endoplasmic reticulum stress, and apoptosis in bronchial epithelial cells via AhR/C	31
Anthocyanin oligomers stimulate browning in 3T3‐L1 white adipocytes via activation of the β3‐adrenergic receptor and ERK signaling pathway	31
Peiminine regulates bone‐fat balance by canonical Wnt/β‐catenin pathway in an ovariectomized rat model	30
Withanolides: Promising candidates for cancer therapy	30
Neuroinflammation inhibition and neuroprotective effects of purpurin, a potential anti‐AD compound, screened via network proximity and gene enrichment analyses	29
Traditional medicinal plants in the treatment of gastrointestinal parasites in humans: A systematic review and meta‐analysis of clinical and experimental evidence	29
Artemether Ameliorates Non‐Alcoholic Steatohepatitis by Restraining Cross‐Talk Between Lipotoxicity‐Induced Hepatic Hepatocytes and Macrophages	29
Columbianadin Ameliorates Myocardial Injury by Inhibiting Autophagy Through the PI3K/Akt/mTOR Signaling Pathway in AMI Mice and Hypoxic H9c2 Cells	29
Current clinical developments in curcumin‐based therapeutics for cancer and chronic diseases	29
Salvianolic Acid B Inhibits ZBP1‐Mediated PANoptosis in Mycobacterium tuberculosis‐Infected Macrophages by Targeting TNFR1	29
Efficacy of Extracts of Oleogum Resin of Boswellia in the Treatment of Knee Osteoarthritis: A Systematic Review and Meta‐Analysis	29
Oxyimperatorin Suppresses the Pathologies of Rheumatoid Arthritis and the Growth of Synovial Organoids Through Targeting the PI3K/AKT Pathway	29
Xanthotoxin (8‐methoxypsoralen): A review of its chemistry, pharmacology, pharmacokinetics, and toxicity	28
A Review on Antifungal Activity of Plant Essential Oils	28
Erucin Alleviates Cardiac Hypertrophy by Improving Mitochondrial Function via Nrf2‐Sirt3 Pathway	28
Formononetin From Sophora flavescens Aiton Alleviates Atopic Dermatitis by Suppressing Neutrophil Extracellular Traps	28
	28
Effects of Dietary Polyphenols on Vasculogenic Erectile Dysfunction: A Systematic Review of Pre‐Clinical Studies	28
Phytochemicals as Modulators of NETosis: A Comprehensive Review on Their Mechanisms and Therapeutic Potential	28
Resistant starch from black rice, Oryza sativaL. var. ameliorates renal inflammation, fibrosis and injury in insulin resistant rats	27
Hypoglycemic Effect of Ginsenoside Compound K Mediated by N‐Acetylserotonin Derived From Gut Microbiota	27
Antitumor effect of luteolin proven by patient‐derived organoids of gastric cancer	27
Chemical constituents, biological activities and anti‐rheumatoid arthritic properties of four citrus essential oils	27
Exploiting new strategies in combating head and neck carcinoma: A comprehensive review on phytochemical approaches passing through PI3K/Akt/mTOR signaling pathway	27
Formononetin Induces Ferroptosis in Activated Hepatic Stellate Cells to Attenuate Liver Fibrosis by Targeting NADPH Oxidase 4	27
Tetrandrine Alleviates Pulmonary Fibrosis by Modulating Lung Microbiota‐Derived Metabolism and Ameliorating Alveolar Epithelial Cell Senescence	27
Pterostilbene Exhibits Broad‐Spectrum Antiviral Activity by Targeting the Enterovirus Capsid, Inactivating Viral Particles, Blocking Viral Binding, and Protecting Mice From Lethal EV‐A	27
	27
Effects of Sumac Supplementation on Lipid Profile: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials	26
The efficacy of curcumin supplementation on serum total antioxidant capacity, malondialdehyde, and disease activity in women with rheumatoid arthritis: A randomized, double‐blind, placebo‐controlled c	26
Perilla seed oil improves bone health by inhibiting bone resorption in healthy Japanese adults: A 12‐month, randomized, double‐blind, placebo‐controlled trial	26
Issue Information	26
Sinigrin Selectively Mitigates the Acute‐Cardiac Inflammatory Response Through an AMPK‐Dependent Mechanism	26
Protective effects of 4‐geranyloxy‐2,6‐dihydroxybenzophenonel on DSS‐induced ulcerative colitis in mice via regulation of cAMP/PKA/CREB and NF‐κB	26
Systematic Review and Network Meta‐Analysis of the Effects of Plant Extracts on Cognitive Function and Quality of Life in Stroke Patients	26
Salidroside improves blood–brain barrier integrity and cognitive function in hypobaric hypoxia mice by inhibiting microglia activation through GSK3β	26
The potential health benefits of aloin from genus Aloe	25
Increasing brain glucose uptake by Gypenoside LXXV ameliorates cognitive deficits in a mouse model of diabetic Alzheimer's disease	25
Zeylenone synergizes with cisplatin in osteosarcoma by enhancing DNA damage, apoptosis, and necrosis via the Hsp90/AKT/GSK3β and Fanconi anaemia pathway	25
The effects of flavonoids in experimental sepsis: A systematic review and meta‐analysis	25
Potato protease inhibitor II prevents obesity by inducing browning of white adipose tissue in mice via β3 adrenergic receptor signaling pathway	25
Phytochemicals mediated modulation of microRNAs and long non‐coding RNAs in cancer prevention and therapy	25
Magnolol alleviates pulmonary fibrosis inchronic obstructive pulmonary disease by targeting transient receptor potential vanilloid 4‐ankyrin repeat domain	25
Isoliquiritigenin Exhibits Anti‐Inflammatory Responses in Acute Lung Injury by Covalently Binding to the Myeloid Differentiation Protein‐2 Domain	25
Harnessing Dietary Phytochemicals to Modulate Signaling Pathways in Cancer Chemoprevention—A Review	25
Ginsenoside Compound K Mitigates Mitochondrial Fission Through Bile Acid Receptors/YAP Signaling to Counteract Podocyte Injury in Lupus Nephritis	24
Germacrone alleviates breast cancer‐associated osteolysis by inhibiting osteoclastogenesis via inhibition of MAPK/NF‐κB signaling pathways	24
A review on phytoestrogens: Current status and future direction	24
Reniformin A Suppresses Triple‐Negative Breast Cancer Progression by Inducing DRP1‐Mediated Mitochondrial Dysfunction and Apoptosis	24
Combination of Salviae Miltiorrhizae Radix et Rhizoma and Carthami Flos improves cardiac function of diabetic cardiomyopathy mice by regulating the unfolded protein response signaling pathway	24
Tanshinone IIA improves contextual fear‐ and anxiety‐like behaviors in mice via the CREB/BDNF/TrkB signaling pathway	24
Phytosomes as a New Frontier and Emerging Nanotechnology Platform for Phytopharmaceuticals: Therapeutic and Clinical Applications	24
Behavioral and Neuroprotective Properties of the Phytoestrogen 8‐Prenylnaringenin (8‐PN) in Ovariectomized Mice	24
Total flavonoids of Rhizoma drynariae promote angiogenesis and osteogenesis in bone defects	24
A Systematic Review and Meta‐Analysis of Randomized Controlled Trials on the Impact of Resveratrol Supplementation on Anthropometric Indices in Patients With Type 2 Diabetes	23

Issue Information	23
Curdione inhibits ferroptosis in isoprenaline‐induced myocardial infarction via regulating Keap1/Trx1/GPX4 signaling pathway	23
The pharmacological effects of Berberine and its therapeutic potential in different diseases: Role of the phosphatidylinositol 3‐kinase/AKT signaling pathway	23
A comprehensive review of antitumor properties of Angelica species and their antitumor‐responsible constituents and the underlying molecular mechanisms involved in tumor inhibition	23
Effects of adjuvant berberine therapy on acute ischemic stroke: A meta‐analysis	23
Unlocking the Therapeutic Potential of Autophagy Modulation by Natural Products in Tackling Non‐Alcoholic Fatty Liver Disease	23
Total glucosides of white paeony capsule alleviate articular cartilage degeneration and aberrant subchondral bone remodeling in knee osteoarthritis	23
Curcumin suppressed the proliferation and apoptosis of HPV‐positive cervical cancer cells by directly targeting the E6 protein	23
The 6‐month effect of whole soy and purified isoflavones daidzein on thyroid function—A double‐blind, randomized, placebo controlled trial among Chinese equol‐producing po	23
Hepatoprotective effect of dietary pterostilbene against high‐fat‐diet‐induced lipid accumulation exacerbated by chronic jet lag via SIRT1 and SIRT3 activation	23
Taxifolin‐mediated Nrf2 activation ameliorates oxidative stress and apoptosis for the treatment of glucocorticoid‐induced osteonecrosis of the femoral head	23
Celastrol Suppresses SHH‐MB Growth via ROS‐Induced Stress: Evidence From In Vitro and In Vivo Studies	23
Wogonin and its analogs for the prevention and treatment of cancer: A systematic review	23
The role of natural products as PCSK9 modulators: A review	23
Pretreatment with Notoginsenoside R1 attenuates high‐altitude hypoxia‐induced cardiac injury via activation of the ERK1/2‐P90RSK‐Bad signaling pathway in rats	23
Ameliorative effect ofLuffa cylindricafruits onCaenorhabditis elegansand cellular models of Alzheimer's disease‐related pathology via autophagy induction	23
Ursolic acid inhibits the activation of smoothened‐independent non‐canonical hedgehog pathway in colorectal cancer by suppressing AKT signaling cascade	23
Anticancer and chemopreventive potential of Morinda citrifolia L. bioactive compounds: A comprehensive update	22
Poncirus trifoliata Extract and Its Active Coumarins Alleviate Dexamethasone‐Induced Skeletal Muscle Atrophy by Regulating Protein Synthesis, Mitochondrial Biogenesis, and Gut Microb	22
Potential mechanism of oral baicalin treating psoriasis via suppressing Wnt signaling pathway and inhibiting Th17/IL‐17 axis by activating PPARγ	22
Pomegranate effects on the health aspects of women during peri‐ and postmenopause: A systematic review and meta‐analysis	22
Antcin A, a phytosterol regulates SARS‐CoV‐2 spike protein‐mediated metabolic alteration in THP‐1 cells explored by the 1H‐NMR‐based metabolomics approach	22
The SLCO4A1‐Mediated Transmembrane Transport of Lysionotin Attenuates Acute Lung Injury Through Activating the AMPK/Nrf2 Signaling Pathway	22
The therapeutic effects of berberine against different diseases: A review on the involvement of the endoplasmic reticulum stress	22
Natural Compounds Exert Anti‐Obesity Effects by Regulating Cytokines	22
Effects of sea buckthorn (Hippophae rhamnoides L.) on factors related to metabolic syndrome: A systematic review and meta‐analysis of randomized controlled trial	22
	22
Plant‐derived virulence arresting drugs as novel antimicrobial agents: Discovery, perspective, and challenges in clinical use	22
Cancer metabolism control by natural products: Pyruvate kinase M2 targeting therapeutics	22
Maslinic Acid Ameliorates DSS‐Induced Experimental Colitis by Suppressing Th Cell‐Mediated Inflammation via AICD Induction	22
A Marine‐Derived Small Molecule Inhibits Prostate Cancer Growth by Promoting Endoplasmic Reticulum Stress Induced Apoptosis and Autophagy	22
Potential use of curcumin against methicillin‐resistant Staphylococcus infection	22
Paeoniflorin‐6′‐O‐benzene sulfonate protected the intestinal epithelial barrier by restoring the inhibitory effect of GRK2 and β‐arrestin 2 on ERK1/2‐NF‐κB	22
Medicinal herbs consumption in relation to cardiometabolic indices and coronary artery stenosis in participants undergoing coronary angiography: A cross‐sectional study	22
Effects of licorice root supplementation on liver enzymes, hepatic steatosis, metabolic and oxidative stress parameters in women with nonalcoholic fatty liver disease: A randomized double‐blind clinic	21
Licochalcone A inhibits MAS‐related GPR family member X2‐induced pseudo‐allergic reaction by suppressing nuclear migration of nuclear factor‐κB	21
Thymol inTrachyspermum ammiseed extract exhibits neuroprotection, learning, and memory enhancement in scopolamine‐induced Alzheimer's disease mouse model	21
Naringin protects against inflammation and apoptosis induced by intestinal ischemia–reperfusion injury through deactivation of cGAS‐STING signaling pathway	21
The therapeutic potential of typical plant‐derived compounds for the management of metabolic disorders	21
Isoferulic Acid Mitigates Acute Lung Injury Induced by Sepsis Through the Inhibition of JAK2	21
Honokiol inhibits epithelial–mesenchymal transition and hepatic fibrosis via activation of Ecadherin/GSK3β/JNK and inhibition of AKT/ERK/p38/β‐catenin/	21
Pomegranate polyphenol punicalagin improves learning memory deficits, redox homeostasis, and neuroinflammation in aging mice	21
Cannabidiol tempers alcohol intake and neuroendocrine and behavioural correlates in alcohol binge drinking  adolescent rats. Focus on calcitonin gene‐related peptide's brain levels	21
Moringa oleiferaLam. as a potential plant for alleviation of the metabolic syndrome—A narrative review based on in vivo and clinical studies	21
Molecular dynamics simulation and in vitro evaluation of herb–drug interactions involving dietary polyphenols and CDK inhibitors in breast cancer chemotherapy	21
Tussilagone ameliorates high‐fat diet‐induced hepatic steatosis by enhancing energy metabolism and antioxidant activity	21
Yerba mate (Ilex paraguariensis A. St.‐Hil.) for new therapeutic and nutraceutical interventions: A review of patents issued in the last 20 years (2000–2020)	21
Quercetin prevented diabetic nephropathy by inhibiting renal tubular epithelial cell apoptosis via the PI3K/AKT pathway	20
Issue Information	20
Current therapeutic targets and multifaceted physiological impacts of caffeine	20
Proteomic and metabolomic approaches elucidate the molecular mechanism of emodin against neuropathic pain through modulating the gamma‐aminobutyric acid (GABA)‐ergic pathway and PI3K	20
In vitro characterization of iridoid and phenylethanoid glycosides from Cistanche phelypaea for nutraceutical and pharmacological applications	20
Integrated Microbiome and Metabolomic to Explore the Mechanism of Coptisine in Alleviating Ulcerative Colitis	20
Issue Information	20
	20
Neurological recovery and neurogenesis by curcumin sustained‐release system cross‐linked with an acellular spinal cord scaffold in rat spinal cord injury: TargetingNLRP3inflammasome pathway	20
Curcumin: A Potential Detoxifier Against Chemical and Natural Toxicants	20
Beneficial effects of Ginkgo biloba leaf extract on inflammatory markers: A systematic review and meta‐analysis of the clinical trials	20
Identification of Cannabidiolic and Cannabigerolic Acids as MTDL AChE, BuChE, and BACE‐1 Inhibitors Against Alzheimer's Disease by In Silico, In Vitro, and In Vivo Stu	20
Kaempferol's potential effects againstSARS‐CoV‐2 andCOVID‐19‐associated cancer progression and chemo‐resistance	20
Ginger polysaccharide promotes myeloid‐derived suppressor cell apoptosis by regulating lipid metabolism	20
Effect of rosemary leaf powder with weight loss diet on lipid profile, glycemic status, and liver enzymes in patients with nonalcoholic fatty liver disease: A randomized, double‐blind clinical trial	19
Myricetin reverses epithelial–endothelial transition and inhibits vasculogenic mimicry and angiogenesis of hepatocellular carcinoma by directly targeting PAR1	19
Comparing the activity of propolis‐loaded nanoparticles or hydroethanolic extract on cytokine production by peripheral blood mononuclear cells	19
	19
Eleutheroside B‐loaded poly (lactic‐co‐glycolic acid) nanoparticles protect against renal fibrosis via Smad3‐dependent mechanism	19
Poricoic Acid A, an Active Ingredient Extracted From Poria cocos, Inhibits Lung Cancer Cell Growth by Suppressing MEK/ERK Signaling Pathway	19
Icariin, a phytoestrogen, exerts rapid estrogenic actions through crosstalk of estrogen receptors in osteoblasts	19
Green tea extract ameliorates macrophage‐driven emphysematous lesions in chronic obstructive pulmonary disease induced by cigarette smoke condensate	19
Tenuifolin ameliorates chronic restraint stress‐induced cognitive impairment in C57BL/6J mice	19
Role of herbal medicine for prevention and treatment of migraine	19
The effects of Capsicum annuum supplementation on lipid profiles in adults with metabolic syndrome and related disorders: A systematic review and meta‐analysis of randomized controlled trials	19
Salvianolic acid B alleviates autoimmunity in Treg‐deficient mice via inhibiting IL2‐STAT5 signaling	19
Anti‐inflammatory effect of dictamnine on allergic rhinitis via suppression of the LYN kinase‐mediated molecular signaling pathway during mast cell activation	19
An extensive review on phytochemistry and pharmacological activities of Indian medicinal plantCelastrus paniculatusWilld	19
A Comprehensive Review of Biologically Active Natural Products on Human Papillomavirus (HPV) at a Glance	19
Cryptotanshinone alleviates radiation‐induced lung fibrosis via modulation of gut microbiota and bile acid metabolism	19
Aqueous extract ofCeratonia siliquaL. leaves elicits antioxidant, anti‐inflammatory, andAChEinhibiting effects in amyloid‐β42‐induced cognitive deficit mice: Role ofα7‐nAChR	19
Advances in Research on Marine Natural Products for Modulating the Inflammatory Microenvironment	19
Quercetin as a cancer chemopreventive or chemotherapeutic agent: Where we stand	19
Hesperidin reduces systolic blood pressure in diabetic patients and has no effect on blood pressure in healthy individuals: A systematic review and meta‐analysis	19
Crosstalk between traditional Chinese medicine‐derived polysaccharides and the gut microbiota: A new perspective to understand traditional Chinese medicine	19
Agrimoniin is a dual inhibitor of AKT and ERK pathways that inhibit pancreatic cancer cell proliferation	19
Issue Information	18
Insights into the anti‐Candida albicans properties of natural phytochemicals: An in vitro and in vivo investigation	18
An adventure from a work in progress: Challenges and opportunities of pharmacophylogeny in combat against COVID‐19	18
A randomized, double‐blind, placebo‐controlled study on immune improvement effects of ethanolic extract of Echinacea purpurea (L.) Moench in Korean adults	18
7‐Hydroxyflavone improves nonalcoholic fatty liver disease by acting on STK24	18
Mushrooms and Colorectal Cancer: Unveiling Mechanistic Insights and Therapeutic Innovations	18
Propolis as an adjunctive therapy for treatment of uncomplicated cystitis in women: A randomized double‐blind placebo‐controlled trial	18
Efficacy of herbal treatments for functional dyspepsia: Meta‐analyses after subgroup reclassification	18
Issue Information	18
Suspected adverse reactions to medications and food supplements containing Serenoa repens: A worldwide analysis of pharmacovigilance and phytovigilance spontaneous reports	18
Comments on: Unveiling the therapeutic promise of natural products in alleviating drug‐induced liver injury: Present advancements and future prospects	18
Echinocystic acid prevents obesity and fatty liver via interacting withFABP1	18