Phytotherapy Research

Papers
(The median citation count of Phytotherapy Research is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)
ArticleCitations
Harnessing Essential Oils for Acetylcholinesterase Inhibition: A Literature Review154
Targeting Mitochondrial Dysfunction by Natural Products for the Treatment of Diabetic Kidney Disease133
Phytochemicals targeting ferroptosis in cardiovascular diseases: Recent advances and therapeutic perspectives120
The influence of propolis plus Hyoscyamus niger L. against COVID‐19: A phase II, multicenter, placebo‐controlled, randomized trial119
RETRACTION: Epigallocatechin‐3‐Gallate Enhances Differentiation of Acute Promyelocytic Leukemia Cells via Inhibition of PMLRARα and HDAC1114
Antiplatelet effect of ginkgo diterpene lactone meglumine injection in acute ischemic stroke: A randomized, double‐blind, placebo‐controlled clinical trial108
Correction to “Antiinflammatory Effects and Chemical Constituents of Veronicastrum axillare103
Curcumin as a therapeutic agent in cancer therapy: Focusing on its modulatory effects on circularRNAs97
Effects of gypenoside L‐containingGynostemma pentaphyllumextract on fatigue and physical performance: A double‐blind, placebo‐controlled, randomized trial95
Maltol mitigates cisplatin‐evoked cardiotoxicity via inhibiting the PI3K/Akt signaling pathway in rodents in vivo and in vitro94
The effect of propolis supplementation on cardiovascular risk factors in women with rheumatoid arthritis: A double‐blind, placebo, controlled randomized clinical trial92
Bryodulcosigenin attenuates bleomycin‐induced pulmonary fibrosis via inhibiting AMPK‐mediated mesenchymal epithelial transition and oxidative stress90
Ethanol extract of Pueraria lobata improve acute myocardial infarction in rats via regulating gut microbiota and bile acid metabolism80
The effects of spirulina intake on clinical and metabolic parameters in Alzheimer's disease: A randomized, double‐blind, controlled trial80
Natural compounds as obesity pharmacotherapies80
Piperine Improves DSS‐Induced Colitis in Mice via Inhibition of Inflammation and Modulation of Gut Microbiota75
Modulation of miRNAs by Phytochemicals in Cerebral Ischemia: A Systematic Review of In Vitro and In Vivo Studies73
Harnessing the Potential of Carotenoids for Cancer Therapy: An Integrated Machine Learning and MST Based Approach71
Efficacy of frankincense‐based herbal product in urinary incontinence: A randomized, double‐blind, placebo‐ and active‐controlled clinical trial67
Effects of different natural products in patients with non‐alcoholic fatty liver disease—A network meta‐analysis of randomized controlled trials66
Astragalin Inhibits Oxidative Stress‐Induced Pyroptosis and Apoptosis in Mouse Models of Renal Ischemia/Reperfusion Injury by Activating the SIRT1/Nrf2 Pathway65
Phytoncides could potentially inhibit the spike protein of SARS‐CoV‐2 variants63
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Xanthohumol Regulates Mitophagy in Osteosarcoma Cells via AMPKULK1FUNDC1 Signaling Pathway62
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Co‐administration of sub‐effective doses of the constituents of Crocus sativus L. crocins with those of the antipsychotics clozapine and risperidone counteract memory deficits caused by blockad59
Pharmacovigilance of unlicensed cannabidiol in European countries58
Polysaccharides (pectin, mucilage, and fructan inulin) and their fermented products: A critical analysis of their biochemical, gut interactions, and biological functions as antidiabetic agents57
Saponin monomers: Potential candidates for the treatment of type 2 diabetes mellitus and its complications56
Safety assessment and adverse drug reaction reporting of tea tree oil (Melaleuca aetheroleum)54
Vegetable‐derived indole enhances the melanoma‐treating efficacy of chemotherapeutics53
Schisandra B, a representative lignan from Schisandra chinensis, improves cisplatin‐induced toxicity: An in vitro study53
Curculigoside rescues hippocampal synaptic deficits elicited by PTSD through activating cAMP‐PKA signaling51
Unleashing the Therapeutic Power of Natural Alkaloids in Triple‐Negative Breast Cancer: State‐of‐the‐Art Advances and Future Directions50
Preclinical studies of the antitumor effect of curcumin‐loaded polymeric nanocapsules: A systematic review and meta‐analysis50
Phase III randomized clinical trial of BV‐4051, an Ayurvedic polyherbal formulation in moderate SARS‐CoV‐2 infections and its impact on inflammatory biomarkers48
Zingibroside R1 Isolated From Achyranthes bidentata Blume Ameliorates LPS/D‐GalN‐Induced Liver Injury by Regulating Succinic Acid Metabolism via the 48
Ellagitannin Component Punicalin Ameliorates Cognitive Dysfunction, Oxidative Stress, and Neuroinflammation via the Inhibition of cGASSTING Signaling in the Brain of an Aging Mo48
Polydatin as a therapeutic alternative for central nervous system disorders: A systematic review of animal studies48
Astragaloside IV Alleviates Acute Hepatic Injury by Regulating Macrophage Polarization and Pyroptosis via Activation of the AMPK/SIRT1 Signaling Pathway48
Anti‐Warburg effect via generation of ROS and inhibition of PKM2/β‐catenin mediates apoptosis of lambertianic acid in prostate cancer cells48
Dietary plants for oral cancer prevention and therapy: A review of preclinical and clinical studies46
4′‐Hydroxychalcone Induces Ferroptosis in Glioblastoma Through the xCT/GSH/GPX4 Axis Under the Regulation of the AKT/mTORC1/4EBP1 Path46
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Substantial Effects of Carotenoids on Skin Health: A Mechanistic Perspective44
Ouratein D, a Biflavanone From Ouratea spectabilis, Alleviates Betacoronavirus Infection by Mitigating Inflammation, Lung Damage and Viral Replication44
The effects of Garcinia cambogia (hydroxycitric acid) on lipid profile: A systematic review and meta‐analysis of randomized controlled trials44
Bavachinin selectively modulates PPAR γ and maintains bone homeostasis in Type 2 Diabetes43
Fangchinoline abrogates growth and survival of hepatocellular carcinoma by negative regulation of c‐met/HGF and its associated downstream signaling pathways43
Brazilian red propolis exerts a cytotoxic action against prostate cancer cells and upregulates human monocyte functions42
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Immunostimulant plant proteins: Potential candidates as vaccine adjuvants42
Mechanisms and Potential of Antitumor Therapy With Natural Products Regulating Non‐Coding RNAs42
The alleviative effect of flavonol‐type Nrf2 activator rhamnazin from Physalis alkekengi L. var. franchetii (Mast.) Makino on pulmonary disorders41
Issue Information41
Urolithin A alleviates acute kidney injury induced by renal ischemia reperfusion through the p62‐Keap1‐Nrf2 signaling pathway40
Nootkatone alleviates rotenone‐induced Parkinson's disease symptoms through activation of the PI3K/Akt signaling pathway40
Exploring the therapeutic implications of natural compounds modulating apoptosis in vascular dementia40
Trilobatin promotes angiogenesis after cerebral ischemia–reperfusion injury via SIRT7/VEGFA signaling pathway in rats39
Therapeutic Potential of Chinese Herbal Medicine and Underlying Mechanism for the Treatment of Myocardial Infarction38
A grape (Vitis vinifera L.) pomace water extract modulates inflammatory and immune response in SW‐480 cells and isolated mouse colon38
Hyperoside prevents doxorubicin‐induced cardiotoxicity by inhibiting NOXs/ROS/NLRP3 inflammasome signaling pathway38
Costunolide protects against alcohol‐induced liver injury by regulating gut microbiota, oxidative stress and attenuating inflammation in vivo and in vitro38
Xanthohumol Alleviates Inflammatory Bowel Disease‐Associated Osteoporosis via Regulating Gut Microbial Metabolites37
SH‐PRO extract alleviates benign prostatic hyperplasia via ROS‐mediated activation of PARP/caspase 3 and inhibition of FOXO3a/AR/PSA s37
Jatrorrhizine alleviates cytokine storm secondary lung injury via regulating CD39‐dominant purinergic braking and downstream NLRP3 inflammasome37
Upregulation of key factors of viral entry of corona‐ and influenza viruses upon TLR3‐signaling in cells from the respiratory tract and clinical treatment options by 1,8‐Cineol36
Mitochondrial‐targeted curcumin inhibits T‐cell activation via Nrf2 and inhibits graft‐versus‐host‐disease in a mouse model36
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Natural products targeting macroautophagy signaling in hepatocellular carcinoma therapy: Recent evidence and perspectives35
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Morus alba L. water extract changes gut microbiota and fecal metabolome in mice induced by high‐fat and high‐sucrose diet plus low‐dose streptozotocin35
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Curcumin supplementation as a complementary and alternative medicine for COVID‐19 patients35
Cardiovascular benefits of Eruca sativa mill. Defatted seed meal extract: Potential role of hydrogen sulfide35
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Lotusine ameliorates propionic acid‐induced autism spectrum disorder‐like behavior in mice by activating D1 dopamine receptor in medial prefrontal cortex35
Is the mushroom Meripilus giganteus a potential cancer chemopreventive agent?34
Phytocompounds and COVID‐19: Two years of knowledge34
A randomized, double‐blind, placebo‐controlled study of Cistanche tubulosa and Ginkgo biloba extracts for the improvement of cognitive function in middle‐aged and elderly people33
Salvianolic Acid B Inhibits ZBP1‐Mediated PANoptosis in Mycobacterium tuberculosis‐Infected Macrophages by Targeting TNFR133
Erucin Alleviates Cardiac Hypertrophy by Improving Mitochondrial Function via Nrf2‐Sirt3 Pathway33
miRNA, phytometabolites and disease: Connecting the dots33
Resistant starch from black rice, Oryza sativaL. var. ameliorates renal inflammation, fibrosis and injury in insulin resistant rats33
Tetrandrine Alleviates Pulmonary Fibrosis by Modulating Lung Microbiota‐Derived Metabolism and Ameliorating Alveolar Epithelial Cell Senescence33
Trifolirhizin reduces osteoclast formation and prevents inflammatory osteolysis by inhibiting RANKL‐induced activation of NF‐κB and MAPK signaling pathways and ROS33
Effects of Dietary Polyphenols on Vasculogenic Erectile Dysfunction: A Systematic Review of Pre‐Clinical Studies33
Oxyimperatorin Suppresses the Pathologies of Rheumatoid Arthritis and the Growth of Synovial Organoids Through Targeting the PI3K/AKT Pathway32
Formononetin From Sophora flavescens Aiton Alleviates Atopic Dermatitis by Suppressing Neutrophil Extracellular Traps32
Therapeutic effect of Eleutherococcus senticosus (Rupr. & Maxim.) Maxim. leaves on ischemic stroke via the microbiota–gut–brain axis32
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Ginkgo Flavone Aglycone Ameliorates Atherosclerosis via Inhibiting Endothelial Pyroptosis by Activating the Nrf2 Pathway32
Artemether Ameliorates Non‐Alcoholic Steatohepatitis by Restraining Cross‐Talk Between Lipotoxicity‐Induced Hepatic Hepatocytes and Macrophages32
Effects of ginseng consumption on the biomarkers of oxidative stress: A systematic review and meta‐analysis32
Pterostilbene Exhibits Broad‐Spectrum Antiviral Activity by Targeting the Enterovirus Capsid, Inactivating Viral Particles, Blocking Viral Binding, and Protecting Mice From Lethal EVA32
Astragaloside IV ameliorates radiation‐induced nerve cell damage by activating the BDNF/TrkB signaling pathway31
Efficacy of Extracts of Oleogum Resin of Boswellia in the Treatment of Knee Osteoarthritis: A Systematic Review and Meta‐Analysis31
An exploratory double‐blind, randomized, placebo‐controlled study to assess the efficacy of CitruSlim on body composition and lipid parameters in obese individuals31
Exploiting new strategies in combating head and neck carcinoma: A comprehensive review on phytochemical approaches passing through PI3K/Akt/mTOR signaling pathway31
Natural products in suppressing glioma progression: A focus on the role of microRNAs31
A Review on Antifungal Activity of Plant Essential Oils30
The effect of saffron (Crocus sativus L.) on glycemia, lipid profile, and antioxidant status in patients with type‐2 diabetes mellitus: A randomized placebo‐controlled trial30
Traditional medicinal plants in the treatment of gastrointestinal parasites in humans: A systematic review and meta‐analysis of clinical and experimental evidence30
Cornuside, by regulating the AGEs‐RAGE‐IκBα‐ERK1/2 signaling pathway, ameliorates cognitive impairment associated with brain aging30
Withanolides: Promising candidates for cancer therapy30
Columbianadin Ameliorates Myocardial Injury by Inhibiting Autophagy Through the PI3K/Akt/mTOR Signaling Pathway in AMI Mice and Hypoxic H9c2 Cells30
Formononetin attenuates cigarette smoke‐induced COPD in mice by suppressing inflammation, endoplasmic reticulum stress, and apoptosis in bronchial epithelial cells via AhR/C29
Helichrysum stoechas (L.) Moench reduces body weight gain and modulates mood disorders via inhibition of silent information regulator 1 (SIRT1) by arzanol29
Neuroinflammation inhibition and neuroprotective effects of purpurin, a potential anti‐AD compound, screened via network proximity and gene enrichment analyses29
Hypoglycemic Effect of Ginsenoside Compound K Mediated by N‐Acetylserotonin Derived From Gut Microbiota28
Xanthotoxin (8‐methoxypsoralen): A review of its chemistry, pharmacology, pharmacokinetics, and toxicity28
The effects of lycopene supplementation on insulin‐like growth factor‐1 and insulin‐like growth factor binding proteins: A systematic review of randomized controlled trials28
Chemical constituents, biological activities and anti‐rheumatoid arthritic properties of four citrus essential oils28
Effect of sumac powder on clinical symptoms, hyperandrogenism, inflammation, blood glucose, lipid profiles in women with polycystic ovary syndrome: A double‐blind randomized clinical trial27
Efficacy of herbal treatments for functional dyspepsia: A systematic review and meta‐analysis of randomized clinical trials27
Curcumin and nano‐curcumin applications in psychiatric disorders27
Gut microbiota, bile acids, and nature compounds27
Phytochemicals as Modulators of NETosis: A Comprehensive Review on Their Mechanisms and Therapeutic Potential27
Antitumor effect of luteolin proven by patient‐derived organoids of gastric cancer27
Therapeutic considerations of bioactive compounds in Alzheimer's disease and Parkinson's disease: Dissecting the molecular pathways27
Formononetin Induces Ferroptosis in Activated Hepatic Stellate Cells to Attenuate Liver Fibrosis by Targeting NADPH Oxidase 426
Acetylshikonin Derived From Arnebia euchroma (Royle) Johnst Kills Multidrug‐Resistant Gram‐Positive Pathogens In Vitro and In Vivo26
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Effect of walnut consumption on markers of endothelial function in adults: A systematic review and meta‐analysis of randomized controlled trials26
Germacrone alleviates breast cancer‐associated osteolysis by inhibiting osteoclastogenesis via inhibition of MAPK/NF‐κB signaling pathways26
Peiminine regulates bone‐fat balance by canonical Wnt/β‐catenin pathway in an ovariectomized rat model26
Effects of Sumac Supplementation on Lipid Profile: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials26
Salidroside improves blood–brain barrier integrity and cognitive function in hypobaric hypoxia mice by inhibiting microglia activation through GSK3β25
The efficacy of curcumin supplementation on serum total antioxidant capacity, malondialdehyde, and disease activity in women with rheumatoid arthritis: A randomized, double‐blind, placebo‐controlled c25
Potato protease inhibitor II prevents obesity by inducing browning of white adipose tissue in mice via β3 adrenergic receptor signaling pathway25
MicroRNAs for Diabetes Management: From Natural Bioactive Compounds to Nucleotide Networks25
Ursolic acid inhibits the activation of smoothened‐independent non‐canonical hedgehog pathway in colorectal cancer by suppressing AKT signaling cascade25
Increasing brain glucose uptake by Gypenoside LXXV ameliorates cognitive deficits in a mouse model of diabetic Alzheimer's disease25
Reniformin A Suppresses Triple‐Negative Breast Cancer Progression by Inducing DRP1‐Mediated Mitochondrial Dysfunction and Apoptosis25
Effects of adjuvant berberine therapy on acute ischemic stroke: A meta‐analysis25
Behavioral and Neuroprotective Properties of the Phytoestrogen 8‐Prenylnaringenin (8‐PN) in Ovariectomized Mice25
A Systematic Review and Meta‐Analysis of Randomized Controlled Trials on the Impact of Resveratrol Supplementation on Anthropometric Indices in Patients With Type 2 Diabetes25
Combination of Salviae Miltiorrhizae Radix et Rhizoma and Carthami Flos improves cardiac function of diabetic cardiomyopathy mice by regulating the unfolded protein response signaling pathway25
Curcumin suppressed the proliferation and apoptosis of HPV‐positive cervical cancer cells by directly targeting the E6 protein25
Isoliquiritigenin Exhibits Anti‐Inflammatory Responses in Acute Lung Injury by Covalently Binding to the Myeloid Differentiation Protein‐2 Domain25
Ginsenoside Compound K Mitigates Mitochondrial Fission Through Bile Acid Receptors/YAP Signaling to Counteract Podocyte Injury in Lupus Nephritis25
The potential health benefits of aloin from genus Aloe25
Phytosomes as a New Frontier and Emerging Nanotechnology Platform for Phytopharmaceuticals: Therapeutic and Clinical Applications25
Celastrol Suppresses SHHMB Growth via ROS‐Induced Stress: Evidence From In Vitro and In Vivo Studies25
Tanshinone IIA improves contextual fear‐ and anxiety‐like behaviors in mice via the CREB/BDNF/TrkB signaling pathway25
Protective effects of 4‐geranyloxy‐2,6‐dihydroxybenzophenonel on DSS‐induced ulcerative colitis in mice via regulation of cAMP/PKA/CREB and NF‐κB24
Wogonin and its analogs for the prevention and treatment of cancer: A systematic review24
Unlocking the Therapeutic Potential of Autophagy Modulation by Natural Products in Tackling Non‐Alcoholic Fatty Liver Disease24
Phytochemicals mediated modulation of microRNAs and long non‐coding RNAs in cancer prevention and therapy24
Issue Information24
Total glucosides of white paeony capsule alleviate articular cartilage degeneration and aberrant subchondral bone remodeling in knee osteoarthritis24
The effects of flavonoids in experimental sepsis: A systematic review and meta‐analysis24
Efficacy and Safety of Curcumin as an Adjuvant to Standard Chemotherapy in Advanced and Metastatic Breast Cancer Patients: A Randomized Controlled Study24
Systematic Review and Network Meta‐Analysis of the Effects of Plant Extracts on Cognitive Function and Quality of Life in Stroke Patients24
Taxifolin‐mediated Nrf2 activation ameliorates oxidative stress and apoptosis for the treatment of glucocorticoid‐induced osteonecrosis of the femoral head24
A review on phytoestrogens: Current status and future direction24
Magnolol alleviates pulmonary fibrosis inchronic obstructive pulmonary disease by targeting transient receptor potential vanilloid 4‐ankyrin repeat domain24
Total flavonoids of Rhizoma drynariae promote angiogenesis and osteogenesis in bone defects24
Perilla seed oil improves bone health by inhibiting bone resorption in healthy Japanese adults: A 12‐month, randomized, double‐blind, placebo‐controlled trial24
Harnessing Dietary Phytochemicals to Modulate Signaling Pathways in Cancer Chemoprevention—A Review24
Sinigrin Selectively Mitigates the Acute‐Cardiac Inflammatory Response Through an AMPK‐Dependent Mechanism24
The SLCO4A1‐Mediated Transmembrane Transport of Lysionotin Attenuates Acute Lung Injury Through Activating the AMPK/Nrf2 Signaling Pathway23
Effects of sea buckthorn (Hippophae rhamnoides L.) on factors related to metabolic syndrome: A systematic review and meta‐analysis of randomized controlled trial23
Pomegranate polyphenol punicalagin improves learning memory deficits, redox homeostasis, and neuroinflammation in aging mice23
The therapeutic effects of berberine against different diseases: A review on the involvement of the endoplasmic reticulum stress23
Pomegranate effects on the health aspects of women during peri‐ and postmenopause: A systematic review and meta‐analysis23
Yerba mate (Ilex paraguariensis A. St.‐Hil.) for new therapeutic and nutraceutical interventions: A review of patents issued in the last 20 years (2000–2020)23
Thymol inTrachyspermum ammiseed extract exhibits neuroprotection, learning, and memory enhancement in scopolamine‐induced Alzheimer's disease mouse model23
Tussilagone ameliorates high‐fat diet‐induced hepatic steatosis by enhancing energy metabolism and antioxidant activity23
The therapeutic potential of typical plant‐derived compounds for the management of metabolic disorders23
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Isoferulic Acid Mitigates Acute Lung Injury Induced by Sepsis Through the Inhibition of JAK223
Pretreatment with Notoginsenoside R1 attenuates high‐altitude hypoxia‐induced cardiac injury via activation of the ERK1/2‐P90RSK‐Bad signaling pathway in rats23
Beneficial effects of Ginkgo biloba leaf extract on inflammatory markers: A systematic review and meta‐analysis of the clinical trials23
Cannabidiol tempers alcohol intake and neuroendocrine and behavioural correlates in alcohol binge drinking  adolescent rats. Focus on calcitonin gene‐related peptide's brain levels23
Plant‐derived virulence arresting drugs as novel antimicrobial agents: Discovery, perspective, and challenges in clinical use23
Antcin A, a phytosterol regulates SARS‐CoV‐2 spike protein‐mediated metabolic alteration in THP‐1 cells explored by the 1H‐NMR‐based metabolomics approach23
Natural Compounds Exert Anti‐Obesity Effects by Regulating Cytokines23
Paeoniflorin‐6′‐O‐benzene sulfonate protected the intestinal epithelial barrier by restoring the inhibitory effect of GRK2 and β‐arrestin 2 on ERK1/2‐NF‐κB23
Integrated Microbiome and Metabolomic to Explore the Mechanism of Coptisine in Alleviating Ulcerative Colitis22
Poncirus trifoliata Extract and Its Active Coumarins Alleviate Dexamethasone‐Induced Skeletal Muscle Atrophy by Regulating Protein Synthesis, Mitochondrial Biogenesis, and Gut Microb22
Cancer metabolism control by natural products: Pyruvate kinase M2 targeting therapeutics22
Curdione inhibits ferroptosis in isoprenaline‐induced myocardial infarction via regulating Keap1/Trx1/GPX4 signaling pathway22
Potential mechanism of oral baicalin treating psoriasis via suppressing Wnt signaling pathway and inhibiting Th17/IL‐17 axis by activating PPARγ22
A Marine‐Derived Small Molecule Inhibits Prostate Cancer Growth by Promoting Endoplasmic Reticulum Stress Induced Apoptosis and Autophagy22
Hepatoprotective effect of dietary pterostilbene against high‐fat‐diet‐induced lipid accumulation exacerbated by chronic jet lag via SIRT1 and SIRT3 activation22
Molecular dynamics simulation and in vitro evaluation of herb–drug interactions involving dietary polyphenols and CDK inhibitors in breast cancer chemotherapy22
Plumbagin Alleviates Mild Traumatic Brain Injury‐Induced Obsessive‐Compulsive Disorder in Mice by Inhibiting nNOS and Augmenting Cortico‐Striatal Serotonin Levels22
Moringa oleiferaLam. as a potential plant for alleviation of the metabolic syndrome—A narrative review based on in vivo and clinical studies22
Maslinic Acid Ameliorates DSS‐Induced Experimental Colitis by Suppressing Th Cell‐Mediated Inflammation via AICD Induction22
Medicinal herbs consumption in relation to cardiometabolic indices and coronary artery stenosis in participants undergoing coronary angiography: A cross‐sectional study22
Naringin protects against inflammation and apoptosis induced by intestinal ischemia–reperfusion injury through deactivation of cGAS‐STING signaling pathway22
Potential use of curcumin against methicillin‐resistant Staphylococcus infection22
Advances in Research on Marine Natural Products for Modulating the Inflammatory Microenvironment21
Effect of rosemary leaf powder with weight loss diet on lipid profile, glycemic status, and liver enzymes in patients with nonalcoholic fatty liver disease: A randomized, double‐blind clinical trial21
A comprehensive review of antitumor properties of Angelica species and their antitumor‐responsible constituents and the underlying molecular mechanisms involved in tumor inhibition21
Effects of licorice root supplementation on liver enzymes, hepatic steatosis, metabolic and oxidative stress parameters in women with nonalcoholic fatty liver disease: A randomized double‐blind clinic21
The role of natural products as PCSK9 modulators: A review21
Kaempferol's potential effects againstSARS‐CoV‐2 andCOVID‐19‐associated cancer progression and chemo‐resistance21
Hesperidin reduces systolic blood pressure in diabetic patients and has no effect on blood pressure in healthy individuals: A systematic review and meta‐analysis21
Salvianolic acid B alleviates autoimmunity in Treg‐deficient mice via inhibiting IL2‐STAT5 signaling21
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Honokiol inhibits epithelial–mesenchymal transition and hepatic fibrosis via activation of Ecadherin/GSK3β/JNK and inhibition of AKT/ERK/p38/β‐catenin/21
The pharmacological effects of Berberine and its therapeutic potential in different diseases: Role of the phosphatidylinositol 3‐kinase/AKT signaling pathway21
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An extensive review on phytochemistry and pharmacological activities of Indian medicinal plantCelastrus paniculatusWilld21
Anti‐inflammatory effect of dictamnine on allergic rhinitis via suppression of the LYN kinase‐mediated molecular signaling pathway during mast cell activation21
Quercetin prevented diabetic nephropathy by inhibiting renal tubular epithelial cell apoptosis via the PI3K/AKT pathway21
Comparing the activity of propolis‐loaded nanoparticles or hydroethanolic extract on cytokine production by peripheral blood mononuclear cells21
Issue Information21
Anticancer and chemopreventive potential of Morinda citrifolia L. bioactive compounds: A comprehensive update21
Ameliorative effect ofLuffa cylindricafruits onCaenorhabditis elegansand cellular models of Alzheimer's disease‐related pathology via autophagy induction21
Jujuboside B Induces Ferroptosis and Overcomes Radioresistance Through the PPARγATF3 ‐Gpx4 Sign21
Role of herbal medicine for prevention and treatment of migraine21
Agrimoniin is a dual inhibitor of AKT and ERK pathways that inhibit pancreatic cancer cell proliferation21
Icariin, a phytoestrogen, exerts rapid estrogenic actions through crosstalk of estrogen receptors in osteoblasts20
The effects of Capsicum annuum supplementation on lipid profiles in adults with metabolic syndrome and related disorders: A systematic review and meta‐analysis of randomized controlled trials20
Identification of Cannabidiolic and Cannabigerolic Acids as MTDL AChE, BuChE, and BACE‐1 Inhibitors Against Alzheimer's Disease by In Silico, In Vitro, and In Vivo Stu20
Ginger polysaccharide promotes myeloid‐derived suppressor cell apoptosis by regulating lipid metabolism20
Quercetin as a cancer chemopreventive or chemotherapeutic agent: Where we stand20
Cryptotanshinone alleviates radiation‐induced lung fibrosis via modulation of gut microbiota and bile acid metabolism20
Neurological recovery and neurogenesis by curcumin sustained‐release system cross‐linked with an acellular spinal cord scaffold in rat spinal cord injury: TargetingNLRP3inflammasome pathway20
Current therapeutic targets and multifaceted physiological impacts of caffeine20
A critical review on clinical evidence of the efficacy of lavender in sleep disorders20
Curcumin: A Potential Detoxifier Against Chemical and Natural Toxicants20
A Comprehensive Review of Biologically Active Natural Products on Human Papillomavirus (HPV) at a Glance20
In vitro characterization of iridoid and phenylethanoid glycosides from Cistanche phelypaea for nutraceutical and pharmacological applications20
Aqueous extract ofCeratonia siliquaL. leaves elicits antioxidant, anti‐inflammatory, andAChEinhibiting effects in amyloid‐β42‐induced cognitive deficit mice: Role ofα7‐nAChR19
Asiaticoside ameliorates DSS‐induced colitis in mice by inhibiting inflammatory response, protecting intestinal barrier and regulating intestinal microecology19
Crosstalk between traditional Chinese medicine‐derived polysaccharides and the gut microbiota: A new perspective to understand traditional Chinese medicine19
Proteomic and metabolomic approaches elucidate the molecular mechanism of emodin against neuropathic pain through modulating the gamma‐aminobutyric acid (GABA)‐ergic pathway and PI3K19
Gardenia jasminoides Ellis. Polysaccharides Alleviated Cholestatic Liver Injury by Increasing the Production of Butyric Acid and FXR Activation19
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Targeting autophagy and neuroinflammation pathways with plant‐derived natural compounds as potential antidepressant agents19
Poricoic Acid A, an Active Ingredient Extracted From Poria cocos, Inhibits Lung Cancer Cell Growth by Suppressing MEK/ERK Signaling Pathway19
Alpinetin alleviates osteoporosis by promoting osteogenic differentiation in BMSCs by triggering autophagy via PKA/mTOR/ULK1 signaling19
Green tea extract ameliorates macrophage‐driven emphysematous lesions in chronic obstructive pulmonary disease induced by cigarette smoke condensate19
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A randomized, double‐blind, placebo‐controlled study on immune improvement effects of ethanolic extract of Echinacea purpurea (L.) Moench in Korean adults19
Curcumin and its anti‐colorectal cancer potential: From mechanisms of action to autophagy19
Fisetin attenuates doxorubicin‐induced cardiotoxicity by inhibiting the insulin‐like growth factor II receptor apoptotic pathway through estrogen receptor‐α/‐β activation19
Myricetin reverses epithelial–endothelial transition and inhibits vasculogenic mimicry and angiogenesis of hepatocellular carcinoma by directly targeting PAR119
Tenuifolin ameliorates chronic restraint stress‐induced cognitive impairment in C57BL/6J mice19
Higher Intake of Resveratrol Is Associated With a Lower Risk of Colorectal Cancer: A Large‐Scale Case–Control Study19
Phyto‐therapeutic potential of Withania somnifera: Molecular mechanism and health implications18
Astaxanthin supplementation impact on insulin resistance, lipid profile, blood pressure, and oxidative stress in polycystic ovary syndrome patients: A triple‐blind randomized clinical trial18
Propolis as an adjunctive therapy for treatment of uncomplicated cystitis in women: A randomized double‐blind placebo‐controlled trial18
Quercetin attenuates the cardiotoxicity of doxorubicin–cyclophosphamide regimen and potentiates its chemotherapeutic effect against triple‐negative breast cancer18
Traditional Chinese medicine for gastric cancer: An evidence mapping18
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