OOIR: Observatory of International Research

Papers

(The TQCC of Biofactors is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)

Article	Citations
Issue Information	347
Issue Information	90
Reactive oxygen species as a double‐edged sword: The role of oxidative enzymes in antitumor therapy	62
Myasthenia gravis: The pharmacological basis of traditional Chinese medicine for its clinical application	57
Attenuation of p38 MAPK/NF‐κB/TRPV1/CGRP is involved in the antinociceptive effect of hesperidin methyl chalcone and taxifolin in paclitaxel‐indu	56
	54
Golgi stress response: A regulatory mechanism of Golgi function	51
Diverse Inhibitors of De Novo Purine Synthesis Promote AICAR‐Induced AMPK Activation and Glucose Uptake in L6 Myotubes	50
Formation of Plant Derived Bioactive Peptides During Simulated Gastro‐Intestinal Digestion: A Systematic Review	49
Investigating rutin as a potential transforming growth factor‐β type I receptor antagonist for the inhibition of bleomycin‐induced lung fibrosis	48
Issue Information	47
Retraction	46
Lactate dehydrogenase A is implicated in the pathogenesis of B‐cell lymphoma through regulation of the FER signaling pathway	41
Long non‐coding RNA LINC01224 plays an oncogenic role in endometrial cancer via miR‐4673/TPX2 axis and activating Wnt/β‐catenin signaling pathway	39
Recent research progress of biologically active peptides	37
Long‐Term Intake of Oleic Acid‐Rich Palm Oil Induces Obesity Without Impairing Hypothalamic Insulin Sensitivity and Redox Activity in Male Wistar Rats	37
Endogenously produced hyaluronan contributes to the regulation of peritoneal adhesion development	33
Is there an interplay between the SARS‐CoV‐2 spike protein and Platelet‐Activating factor?	33
Issue Information ‐ Cover	33
The endocannabinoidome in human placenta: Possible contribution to the pathogenesis of preeclampsia	29
Effects of icariin and curcumol on autophagy, ferroptosis, and lipid metabolism based on miR‐7/m‐TOR/SREBP1 pathway on prostate cancer	29
Rosa gallica and its active compound, cyanidin‐3,5‐O‐diglucoside, improve skin hydration via the GLK signaling pathway	29
N‐methyl‐d‐aspartate receptors: Structure, function, and role in organophosphorus compound poisoning	28
Adipose tissue‐derived mesenchymal stem cells ameliorate cognitive impairment in Alzheimer's disease rat model: Emerging role ofSIRT1	27
Knockdown of integrin β1 inhibits proliferation and promotes apoptosis in bladder cancer cells	26

SEMO‐1, a novel methanethiol oxidase in Caenorhabditis elegans, is a pro‐aging factor conferring selective stress resistance	26
The neuropeptide substance P/neurokinin‐1 receptor system and diabetes: From mechanism to therapy	25
Berberine chloride loaded nano‐PEGylated liposomes attenuates imidacloprid‐induced neurotoxicity by inhibiting NLRP3/Caspase‐1/GSDMD‐mediated pyroptosis	24
The possible role of the nucleoside adenosine in countering skin aging: A review	24
Three months of combination therapy with nano‐curcumin reduces the inflammation and lipoprotein (a) in type 2 diabetic patients with mild to moderate coronary artery disease: Evidence of a randomized,	24
Retraction	24
Correction to “Zerumbone, a ginger sesquiterpene, inhibits migration, invasion, and metastatic behavior of human malignant glioblastoma multiforme in vitro”	24
Deletion of NRF2 disturbs composition, morphology, and differentiation of the murine tail epidermis in chronological aging	23
Exosomal lnc‐AFTR as a novel translation regulator of FAS ameliorates Staphylococcus aureus‐induced mastitis	23
High glucose leads to redistribution of the proteasomal system	22
Tangeretin promotes lifespan associated with insulin/insulin‐like growth factor‐1 signaling pathway and heat resistance in Caenorhabditis elegans	22
Agmatine suppresses glycolysis via the PI3K/Akt/mTOR/HIF‐1α signaling pathway and improves mitochondrial function in microglia exposed to lipopolysaccharide	21
Issue Information ‐ Cover	21
Dietary limonene promotes gastrointestinal barrier function via upregulating tight/adherens junction proteins through cannabinoid receptor type‐1 antagonistic mechanism and alters cellular metabolism	21
	20
Redox‐sensitive signaling pathways in renal cell carcinoma	20
Melatonin protects Kir2.1 function in an oxidative stress‐related model of aging neuroglia	20
The in vitro anti‐cancer synergy of neurokinin‐1 receptor antagonist, aprepitant, and 5‐aminolevulinic acid in glioblastoma	20
Crocetin regulates Th1/Th2 and Th17/Treg balances, nitric oxide production, and nuclear localization of NF‐κB in Th2‐provoked and norm	20
Control of Mycobacterium tuberculosis infection in the elderly: Is there a role for epigenetic reprogramming reversal?	18
Bitter yet beneficial: The dual role of dietary alkaloids in managing diabetes and enhancing cognitive function	18
Deciphering the role of Zn²⁺‐binding histidines from TIA‐1 on the assembly and dynamics of stress granules	18
A novel peptide derived from Haematococcus pluvialis residue balanced lipid metabolism through NHR‐49/PPARα and AAK‐2/AMPK pathways in Caenorhabdi	18
Issue Information	17
Protein concentrations and activities of fatty acid desaturase and elongase enzymes in liver, brain, testicle, and kidney from mice: Substrate dependency	17
Issue Information	17
Issue Information ‐ Cover	16
Proteomic profiling of intestinal epithelial‐like cell‐derived exosomes regulated by epigallocatechin gallate	16
Issue Information ‐ Cover	16
Deubiquitinase PSMD14 promotes tumorigenicity of glioblastoma by deubiquitinating and stabilizing β‐catenin	16
Molecular mechanisms involved in the effects of morin in experimental hepatic encephalopathy	15
A pilot study of the effects of crocin on high‐density lipoprotein cholesterol uptake capacity in patients with metabolic syndrome: A randomized clinical trial	15
Piperine: an emerging biofactor with anticancer efficacy and therapeutic potential	15
Issue Information	15
A new strategy for screening novel functional genes involved in reduction of lipid droplet accumulation	14
Erratum	14
Maternal erythrocyte fatty acid composition as a predictive marker for pregnancy health	14
	14
Effects of calciprotein particles on EMT induction in an in vitro 3D‐cultured proximal tubule epithelial cell model of CKD	14
SP1/CTR1‐mediated oxidative stress‐induced cuproptosis in intervertebral disc degeneration	13
Retraction	13
Gut microbiota contribution to selenium deficiency‐induced gut–liver inflammation	13
Issue Information	13
Correction to “Inhibition of succinate dehydrogenase sensitizes cyclin E‐driven ovarian cancer to CDK inhibition”	13
Protective effect of luteolin against chemical and natural toxicants by targeting NF‐κB pathway	13
	13
Effects of berbamine against myocardial ischemia/reperfusion injury: Activation of the 5' adenosinemonophosphate‐activatedprotein kinase/nuclear factor erythroid2‐relatedfactor p	13
Harnessing tumor‐derived exosomes: A promising approach for the expansion of clinical diagnosis, prognosis, and therapeutic outcome of prostate cancer	12
Insights into an indolicidin‐derived low‐toxic anti‐microbial peptide's efficacy against bacterial cells while preserving eukaryotic cell viability	12
Vitamin D modulates the content of inflammatory microRNAs in extracellular vesicles from human adipocyte cells in inflammatory context	12

	12
Nuclear receptor 4A1 (NR4A1) upregulated by n‐butylidenephthalide via the mitogen‐activated protein kinase (MAPK) pathway ameliorates drug‐induced gingival enlargement	12
Non‐beneficial effects of resveratrol on renal epithelial cell cultures: Implications in cell differentiation	12
Dioscin: A review on pharmacological properties and therapeutic values	12
Echinacoside promotes collagen synthesis and survival via activation of IGF‐1 signaling to alleviate UVB‐induced dermal fibroblast photoaging	12
Navigating the immune landscape with plasma cells: A pan‐cancer signature for precision immunotherapy	12
	12
Identification and validation of the TRHDE‐AS1/hsa‐miR‐449a/ADAMTS5 axis as a novel prognostic biomarker in prostate cancer	11
Retraction	11
Erratum to “Revisiting the therapeutic potential of tocotrienol”	11
Clock system disruption in male Fischer 344 rats fed cafeteria diet and administered sweet treats at different times: The zeitgeber role of grape seed flavanols	11
Extracellular vesicles (EVs): A promising therapeutic tool in the heart tissue regeneration	11
Combinatorial effect of Apigenin‐resveratrol on white adipocyte plasticity and trans‐differentiation for activating lipid metabolism	11
Crocus sativus tepals extract suppresses subcutaneous adipose tissue hypertrophy and improves systemic insulin sensitivity in mice on high‐fat diet	11
Leveraging supramolecular systems in biomedical breakthroughs	11
miR‐222 exerts negative regulation on insulin signaling pathway in 3T3‐L1 adipocytes	11
UPS and Kinases—Gatekeepers of the G1/S Transition	11
	10
The role of LncRNA‐regulated autophagy in AKI	10
miR‐23b/TAB3/NF‐κB/p53 axis is involved in hippocampus injury induced by cerebral ischemia–reperfusion in rats: The protective effect of chlorogenic acid	10
Mechanisms of cancer cell death induction by triptolide	10
	10
Garcinia gummi‐gutta: Phytochemicals and pharmacological applications	9
Melatonin ameliorates trimethyltin chloride‐induced cardiotoxicity: The role of nuclear xenobiotic metabolism and Keap1‐Nrf2/ARE axis‐mediated pyroptosis	9
Correction to EVs Biodistribution and Antifibrotic Impact in Aged Lung Fibrosis Model	9
Issue Information	9
Therapeutic potential of phytochemicals for cystic fibrosis	9
FERM domain‐containing protein 6 exerts a tumor‐inhibiting role in thyroid cancer by antagonizing oncogenic YAP1	9
Retraction	8
Correction to “Untargeted metabolomics reveals biomarkers for the diagnosis of coronary artery plaques as observed by coronary cardiac computed tomography”	8
Gut microbiome–micronutrient interaction: The key to controlling the bioavailability of minerals and vitamins?	8
Cannabinoids in neuroinflammatory disorders: Focusing on multiple sclerosis, Parkinsons, and Alzheimers diseases	8
Resolvin D1: A key endogenous inhibitor of neuroinflammation	8
DISC1 inhibits GSK3β activity to prevent tau hyperphosphorylation under diabetic encephalopathy	8
Issue Information ‐ Cover	8
Fucosterol Promotes Browning in Mouse 3T3‐L1 Adipocytes Through HO‐1/Nrf2 and AMPK Pathways	8
Issue Information ‐ Cover	8
Issue Information ‐ Cover	8
Nrf2 driven macrophage responses in diverse pathophysiological contexts: Disparate pieces from a shared molecular puzzle	8
Noninvasive instrumental evaluation of coenzyme Q₁₀ phytosome on endothelial reactivity in healthy nonsmoking young volunteers: A double‐blind, randomized, placebo‐controlled cro	8
Issue Information ‐ Cover	8
Gut Microbial Metabolite Crosstalk in Crohn's Disease: Network Pharmacology Unveils Dual‐Axis Pathogenesis and Therapeutic Targets	8
Blueberry intervention mitigates detrimental microbial metabolite trimethylamine N‐oxide by modulating gut microbes	8
Issue Information ‐ Cover	8
Autophagy flux inhibition mediated by lysosomal dysfunction participates in the cadmium exposure‐induced cardiotoxicity in swine	8