Biofactors

Papers
(The TQCC of Biofactors is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)
ArticleCitations
Issue Highlights312
Issue Information78
Issue Information55
Attenuation of p38 MAPK/NF‐κB/TRPV1/CGRP is involved in the antinociceptive effect of hesperidin methyl chalcone and taxifolin in paclitaxel‐indu54
Reactive oxygen species as a double‐edged sword: The role of oxidative enzymes in antitumor therapy52
New biomarkers and therapeutic targets of human liver cancer: Transcriptomic findings52
Investigating rutin as a potential transforming growth factor‐β type I receptor antagonist for the inhibition of bleomycin‐induced lung fibrosis52
Golgi stress response: A regulatory mechanism of Golgi function50
48
Myasthenia gravis: The pharmacological basis of traditional Chinese medicine for its clinical application44
Retraction43
Issue Information43
Long non‐coding RNA LINC01224 plays an oncogenic role in endometrial cancer via miR‐4673/TPX2 axis and activating Wnt/β‐catenin signaling pathway40
Lactate dehydrogenase A is implicated in the pathogenesis of B‐cell lymphoma through regulation of the FER signaling pathway38
Recent research progress of biologically active peptides37
Issue Information ‐ Cover37
Rosa gallica and its active compound, cyanidin‐3,5‐O‐diglucoside, improve skin hydration via the GLK signaling pathway35
Correction to “Zerumbone, a ginger sesquiterpene, inhibits migration, invasion, and metastatic behavior of human malignant glioblastoma multiforme in vitro”35
The endocannabinoidome in human placenta: Possible contribution to the pathogenesis of preeclampsia33
Is there an interplay between the SARS‐CoV‐2 spike protein and Platelet‐Activating factor?31
Endogenously produced hyaluronan contributes to the regulation of peritoneal adhesion development30
The neuropeptide substance P/neurokinin‐1 receptor system and diabetes: From mechanism to therapy28
Adipose tissue‐derived mesenchymal stem cells ameliorate cognitive impairment in Alzheimer's disease rat model: Emerging role ofSIRT128
Cip2A modulates osteogenic differentiation via the ERK‐Runx2 pathway in MG63 cells28
The possible role of the nucleoside adenosine in countering skin aging: A review28
Retraction26
Berberine chloride loaded nano‐PEGylated liposomes attenuates imidacloprid‐induced neurotoxicity by inhibiting NLRP3/Caspase‐1/GSDMD‐mediated pyroptosis25
Effects of icariin and curcumol on autophagy, ferroptosis, and lipid metabolism based on miR‐7/m‐TOR/SREBP1 pathway on prostate cancer24
Three months of combination therapy with nano‐curcumin reduces the inflammation and lipoprotein (a) in type 2 diabetic patients with mild to moderate coronary artery disease: Evidence of a randomized,24
N‐methyl‐d‐aspartate receptors: Structure, function, and role in organophosphorus compound poisoning24
SEMO‐1, a novel methanethiol oxidase in Caenorhabditis elegans, is a pro‐aging factor conferring selective stress resistance24
Knockdown of integrin β1 inhibits proliferation and promotes apoptosis in bladder cancer cells23
Issue Information ‐ Cover22
Control of Mycobacterium tuberculosis infection in the elderly: Is there a role for epigenetic reprogramming reversal?22
Retraction22
A novel peptide derived from Haematococcus pluvialis residue balanced lipid metabolism through NHR‐49/PPARα and AAK‐2/AMPK pathways in Caenorhabdi21
Agmatine suppresses glycolysis via the PI3K/Akt/mTOR/HIF‐1α signaling pathway and improves mitochondrial function in microglia exposed to lipopolysaccharide21
21
Crocetin regulates Th1/Th2 and Th17/Treg balances, nitric oxide production, and nuclear localization of NF‐κB in Th2‐provoked and norm21
Dietary limonene promotes gastrointestinal barrier function via upregulating tight/adherens junction proteins through cannabinoid receptor type‐1 antagonistic mechanism and alters cellular metabolism 21
Melatonin protects Kir2.1 function in an oxidative stress‐related model of aging neuroglia20
Deciphering the role of Zn2+‐binding histidines from TIA‐1 on the assembly and dynamics of stress granules20
Redox‐sensitive signaling pathways in renal cell carcinoma20
Bitter yet beneficial: The dual role of dietary alkaloids in managing diabetes and enhancing cognitive function20
Exosomal lnc‐AFTR as a novel translation regulator of FAS ameliorates Staphylococcus aureus‐induced mastitis19
Deletion of NRF2 disturbs composition, morphology, and differentiation of the murine tail epidermis in chronological aging19
The in vitro anti‐cancer synergy of neurokinin‐1 receptor antagonist, aprepitant, and 5‐aminolevulinic acid in glioblastoma19
Tangeretin promotes lifespan associated with insulin/insulin‐like growth factor‐1 signaling pathway and heat resistance in Caenorhabditis elegans18
High glucose leads to redistribution of the proteasomal system18
Dihydroartemisinin alleviates hepatic fibrosis through inducing ferroptosis in hepatic stellate cells18
Temporal correlation of morphological and biochemical changes with the recruitment of different mechanisms of reactive oxygen species formation during human SW872 cell adipogenic differentiation18
Promising effects of gingerol against toxins: A review article17
Protein concentrations and activities of fatty acid desaturase and elongase enzymes in liver, brain, testicle, and kidney from mice: Substrate dependency17
Issue Information ‐ Cover17
Issue Information16
Deubiquitinase PSMD14 promotes tumorigenicity of glioblastoma by deubiquitinating and stabilizing β‐catenin16
Issue Information16
Molecular mechanisms involved in the effects of morin in experimental hepatic encephalopathy16
Issue Information ‐ Cover16
Issue Information15
Piperine: an emerging biofactor with anticancer efficacy and therapeutic potential15
Proteomic profiling of intestinal epithelial‐like cell‐derived exosomes regulated by epigallocatechin gallate15
A pilot study of the effects of crocin on high‐density lipoprotein cholesterol uptake capacity in patients with metabolic syndrome: A randomized clinical trial15
Protective effect of luteolin against chemical and natural toxicants by targeting NF‐κB pathway14
A new strategy for screening novel functional genes involved in reduction of lipid droplet accumulation14
14
Maternal erythrocyte fatty acid composition as a predictive marker for pregnancy health14
Gut microbiota contribution to selenium deficiency‐induced gut–liver inflammation14
Erratum14
Targeting of the tumor microenvironment by curcumin14
Retraction13
SP1/CTR1‐mediated oxidative stress‐induced cuproptosis in intervertebral disc degeneration13
Nuclear receptor 4A1 (NR4A1) upregulated by n‐butylidenephthalide via the mitogen‐activated protein kinase (MAPK) pathway ameliorates drug‐induced gingival enlargement13
Effects of calciprotein particles on EMT induction in an in vitro 3D‐cultured proximal tubule epithelial cell model of CKD13
Issue Information13
Harnessing tumor‐derived exosomes: A promising approach for the expansion of clinical diagnosis, prognosis, and therapeutic outcome of prostate cancer12
Vitamin D modulates the content of inflammatory microRNAs in extracellular vesicles from human adipocyte cells in inflammatory context12
12
Insights into an indolicidin‐derived low‐toxic anti‐microbial peptide's efficacy against bacterial cells while preserving eukaryotic cell viability12
Dioscin: A review on pharmacological properties and therapeutic values12
Correction to “Inhibition of succinate dehydrogenase sensitizes cyclin E‐driven ovarian cancer to CDK inhibition”12
Effects of berbamine against myocardial ischemia/reperfusion injury: Activation of the 5' adenosinemonophosphate‐activatedprotein kinase/nuclear factor erythroid2‐relatedfactor p11
Echinacoside promotes collagen synthesis and survival via activation of IGF‐1 signaling to alleviate UVB‐induced dermal fibroblast photoaging11
Navigating the immune landscape with plasma cells: A pan‐cancer signature for precision immunotherapy11
Non‐beneficial effects of resveratrol on renal epithelial cell cultures: Implications in cell differentiation11
miR‐222 exerts negative regulation on insulin signaling pathway in 3T3‐L1 adipocytes10
Erratum to “Revisiting the therapeutic potential of tocotrienol”10
10
Extracellular vesicles (EVs): A promising therapeutic tool in the heart tissue regeneration10
Clock system disruption in male Fischer 344 rats fed cafeteria diet and administered sweet treats at different times: The zeitgeber role of grape seed flavanols10
Retraction10
10
The role of LncRNA‐regulated autophagy in AKI10
Leveraging supramolecular systems in biomedical breakthroughs10
Combinatorial effect of Apigenin‐resveratrol on white adipocyte plasticity and trans‐differentiation for activating lipid metabolism10
Crocus sativus tepals extract suppresses subcutaneous adipose tissue hypertrophy and improves systemic insulin sensitivity in mice on high‐fat diet9
9
miR‐23b/TAB3/NF‐κB/p53 axis is involved in hippocampus injury induced by cerebral ischemia–reperfusion in rats: The protective effect of chlorogenic acid9
FERM domain‐containing protein 6 exerts a tumor‐inhibiting role in thyroid cancer by antagonizing oncogenic YAP19
Identification and validation of the TRHDE‐AS1/hsa‐miR‐449a/ADAMTS5 axis as a novel prognostic biomarker in prostate cancer9
Therapeutic potential of phytochemicals for cystic fibrosis9
Garcinia gummi‐gutta: Phytochemicals and pharmacological applications9
9
UPS and Kinases—Gatekeepers of the G1/S Transition9
Mechanisms of cancer cell death induction by triptolide9
Issue Information8
Gut microbiome–micronutrient interaction: The key to controlling the bioavailability of minerals and vitamins?8
Issue Information ‐ Cover8
Nrf2 driven macrophage responses in diverse pathophysiological contexts: Disparate pieces from a shared molecular puzzle8
Issue Information ‐ Cover8
Issue Information ‐ Cover8
Correction to “Untargeted metabolomics reveals biomarkers for the diagnosis of coronary artery plaques as observed by coronary cardiac computed tomography”8
DISC1 inhibits GSK3β activity to prevent tau hyperphosphorylation under diabetic encephalopathy8
Retraction8
Issue Information ‐ Cover8
Melatonin ameliorates trimethyltin chloride‐induced cardiotoxicity: The role of nuclear xenobiotic metabolism and Keap1‐Nrf2/ARE axis‐mediated pyroptosis8
Issue Information ‐ Cover8
The cardioprotective effects of nano‐curcumin against doxorubicin‐induced cardiotoxicity: A systematic review8
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