Current Opinion in Immunology

Article	Citations
Editorial overview: Framing the logic of type 2 immunity	264
More X’s, more problems: how contributions from the X chromosomes enhance female predisposition for autoimmunity	182
Animal models of shigellosis: a historical overview	141
Mycobacterial diseases in patients with inborn errors of immunity	84
The future of vaccination in Latin America: learning from the COVID-19 pandemic	82
MITA/STING-mediated antiviral immunity and autoimmunity: the evolution, mechanism, and intervention	72
Editorial Board	70
Better living through chemistry: CRISPR/Cas engineered T cells for cancer immunotherapy	66
Publisher's Note	61
Publisher's Note	59
CD1 displays its own negative regulators	58
Editorial Board	58
Principles of bacterial innate immunity against viruses	57
Therapeutic induction of tolerogenic dendritic cells via aryl hydrocarbon receptor signaling	56
Genome and population dynamics during chronic infection with Helicobacter pylori	55
Humoral immunity at the brain borders in homeostasis	55
The signal transducer and activator of transcription 3 at the center of the causative gene network of the hyper-IgE syndrome	54
Structure–function of type I and III interferons	52
ILC2s – development, divergence, dispersal	50
The value of vaccines	48
Gene: environment interactions in immune and inflammatory responses to severe acute respiratory syndrome coronavirus 2 infection	44
A critical review of measures of childhood vaccine confidence	43
Functional heterogeneity and adaptation of naive T cells in response to tonic TCR signals	43
Autoimmunity, IgE and FcεRI-bearing cells	43
ICOSL in host defense at epithelial barriers: lessons from ICOSLG deficiency	43

Immunology and microbiology: how do they affect social cognition and emotion recognition?	43
Revisiting the role of MRGPRX2 on hypersensitivity reactions to neuromuscular blocking drugs	40
Candidiasis in patients with APS-1: low IL-17, high IFN-γ, or both?	39
Principles and practical applications of structure-based vaccine design	38
Changing the landscape of tumor immunology: novel tools to examine T cell specificity	37
New insights and approaches for analyses of immunopeptidomes	37
Defining the niche for stem-like CD8+ T cell formation and function	36
Oncogenic viruses, cancer biology, and innate immunity	36
Nasal vaccines for pertussis	35
Mitochondrial reactive oxygen species: double agents in Mycobacterium tuberculosis infection	35
Imaging the T-cell receptor: new approaches, new insights	35
IFNε, IFNω and IFNλ: interferons defending the mucosa	34
Carbohydrate metabolism in supporting and regulating neutrophil effector functions	33
Chemokines that govern T cell activity in tumors	33
Help me help you: emerging concepts in T follicular helper cell differentiation, identity, and function	33
Immunometabolic regulation of germinal centers and its implications for aging	33
B cells spatial organization defines their phenotype and function in cancer “Tell me with whom you consort, and I will tell you who you are” ― Goethe	33
The role of interferon in the thymus	33
Host-encoded antivirulence defenses: host physiologies teach pathogens to play nice	31
Discovering mechanisms of macrophage tissue infiltration with Drosophila	31
AP-1 transcription factors in cytotoxic lymphocyte development and antitumor immunity	30
Fuelling B cells: dynamic regulation of B cell metabolism	30
Microbiome modulation of antigen presentation in tolerance and inflammation	29
The path ahead for understanding Toll-like receptor-driven systemic autoimmunity	28
Molecular regulation and dysregulation of T follicular helper cells – learning from inborn errors of immunity	27
Molecular mechanisms regulating T helper 2 cell differentiation and function	27
Major histocompatibility complex class II in the tumor microenvironment: functions of nonprofessional antigen-presenting cells	26
TAP-ing into the cross-presentation secrets of dendritic cells	25
Get into the groove! The influence of TAPBPR on cargo selection	25
Tissue-resident CD8 T cells in central nervous system inflammatory diseases: present at the crime scene and …guilty	24
T cell immunity to cytomegalovirus infection	24
Recent progress in type 1 classical dendritic cell cross-presentation - cytosolic, vacuolar, or both?	24
Why TAPBPR? Implications of an additional player in MHC class I peptide presentation	24
BAFF receptor polymorphisms and deficiency in humans	23
TH17 cell immune adaptation	23
Peptide-dependent tuning of major histocompatibility complex motional properties and the consequences for cellular immunity	23
Gut microbiome-mediated regulation of neuroinflammation	23
Advances and challenges in investigating B-cells via single-cell transcriptomics	22
Immune checkpoint receptors in autoimmunity	21
Intrinsic and extrinsic regulation of IgE B cell responses	21
Cytokine-mediated STAT-dependent pathways underpinning human B-cell differentiation and function	21
COVID-19 vaccines	21
Tryptophan and indole metabolism in immune regulation	20
PANoptosome signaling and therapeutic implications in infection: central role for ZBP1 to activate the inflammasome and PANoptosis	20
Down syndrome and type I interferon: not so simple	20
Major histocompatibility complex class I assembly within endolysosomal pathways	20
HLA variation and antigen presentation in COVID-19 and SARS-CoV-2 infection	20
An easy pill to swallow: oral recombinant vaccines for the 21st century	19
Trained immunity: implications for vaccination	19
Ebola virus disease: current vaccine solutions	19

Inflammasome activation by SARS-CoV-2 and its participation in COVID-19 exacerbation	19
The thymoproteasome in shaping the CD8+ T-cell repertoire	18
‘Persistent germinal center responses: slow-growing trees bear the best fruits’	18
Evolving concepts of host–pathobiont interactions in autoimmunity	17
There is no gene for CVID — novel monogenetic causes for primary antibody deficiency	17
The choroid plexus: a command center for brain–body communication during inflammation	17
Affinity-based clonal selection in Peyer’s patches	17
Functional flexibility and plasticity in immune control of systemic Salmonella infection	17
Atypical B cells in chronic infectious diseases and systemic autoimmunity: puzzles with many missing pieces	17
Editorial Board	16
Editorial overview: Indoles: very busy (and not indolent) molecules at work in immune regulation	16
Editorial overview: BAFF family ligands and receptors – a license to live	16
Editorial Board	16
Editorial overview: Nature repeating itself: conformational flexibility determines MHC class I and class II epitope selection	16
Immunological lessons from genome-wide association studies of infections	15
Epithelial sensing in allergic disease	15
Pharma — manufacturing: the unappreciated and overlooked indispensable skill	15
Infections in activated PI3K delta syndrome (APDS)	15
Editorial Board	15
Mechanisms encoding STAT functional diversity for context-specific inflammatory responses	15
Navigating the metabolic landscape of regulatory T cells: from autoimmune diseases to tumor microenvironments	14
The actin cytoskeleton and mast cell function	14
Genetic and immunological basis of human African trypanosomiasis	14
Innate immune activation and modulatory factors of Helicobacter pylori towards phagocytic and nonphagocytic cells	14
Recent insights into the mechanisms of anaphylaxis	14
Diversity of human NK cell developmental pathways defined by single-cell analyses	14
The nonclassical immune surveillance for ERAAP function	14
Nutritional modulation of antitumor immunity	14
Inborn errors of IKAROS and AIOLOS	14
Next generation immunotherapy: enhancing stemness of polyclonal T cells to improve anti-tumor activity	14
The antiviral state of the cell: lessons from SARS-CoV-2	13
Viral vector vaccines	13
Beyond the gastric epithelium — the paradox of Helicobacter pylori-induced immune responses	12
Endogenous soluble receptors sBCMA and sTACI: biomarker, immunoregulator and hurdle for therapy in multiple myeloma	12
Constitutive and latent immune mechanisms exert ‘silent’ control of virus infections in the central nervous system	12
Infections in the monogenic autoimmune syndrome APECED	12
Editorial Board	12
Inborn errors of STAT1 immunity	12
Increasing hepatitis B vaccination coverage of healthcare workers — global lessons for South Africa	12
Function, occurrence and inhibition of different forms of BAFF	11
Host genetics of innate immune system in infection	11
Some thoughts about what non-mammalian jawed vertebrates are telling us about antigen processing and peptide loading of MHC molecules	11
Dynamic changes in macrophage metabolism modulate induction and suppression of Type I inflammatory responses	11
Monogenic susceptibility to live viral vaccines	11
Navigating the complexity of chronic HIV-1 associated immune dysregulation	11
Insights into the pathogenesis of allergic disease from dedicator of cytokinesis 8 deficiency	10
Necroptosis in immunity, tissue homeostasis, and cancer	10
Turning foes into permissive hosts: manipulation of macrophage polarization by intracellular bacteria	10
Differential signaling by type-I and type-III interferons in mucosa	10
HyperIgE in hypomorphic recombination-activating gene defects	10
Innate antiviral immunity and immunometabolism in hepatocytes	10
Linking signal input, cell state, and spatial context to inflammatory responses	10
The immunometabolic roots of aging	10
Insights into pandemic respiratory viruses: manipulation of the antiviral interferon response by SARS-CoV-2 and influenza A virus	10
Commander-in-chief: monocytes rally the troops for defense against aspergillosis	10
Extracellular matrix–natural killer cell interactome: an uncharted territory in health and disease	10
Tuberculosis as an unconventional interferonopathy	10
Differential induction of T-cell tolerance by tumour fibroblast subsets	9
Bystander activation in memory and antigen-inexperienced memory-like CD8 T cells	9
Vaccine policies in France and Europe	9
Rethinking Toll-like receptor signalling	9
Major histocompatibility complex (MHC) class I and class II proteins: impact of polymorphism on antigen presentation	9
Challenges and opportunities in the development of mucosal mRNA vaccines	9
Type-1 interferon-dependent and -independent mechanisms in cyclic GMP–AMP synthase–stimulator of interferon genes-driven auto-inflammation	9
Immunological insights in the treatment of chronic hepatitis B	9
Safety switches for adoptive cell therapy	9
Two for the price of one: itaconate and its derivatives as an anti-infective and anti-inflammatory immunometabolite	9
Regulation of MHC class II and CD86 expression by March-I in immunity and disease	9
Inflammation, immunity, and antigen persistence in post-acute sequelae of SARS-CoV-2 infection	9
Editorial Board	9
Supply and delivery of vaccines for global health	9
Metabolism and macrophages in the tumor microenvironment	9
Functional subsets of tumor-specific CD8+ T cells in draining lymph nodes and tumor microenvironment	9
Regulation of innate immunity by Nrf2	9
Mapping and modelling human B cell maturation in the germinal centre	9
Positive and negative roles of lipids in mast cells and allergic responses	8
Criteria to make animal studies more relevant to treating human cancer	8
Editorial overview: Tumour immunology: Engineered T cell therapy of cancer: current success and future improvements	8
The number 13 of the family: a proliferation inducing ligand	8
Chasing neoantigens; invite naïve T cells to the party	8

Neuron-intrinsic immunity to viruses in mice and humans	8
Monogenic autoimmunity and infectious diseases: the double-edged sword of immune dysregulation	8
Editorial overview: Human inborn errors of immunity to infection	8
Immunity to EBV as revealed by immunedeficiencies	8
Beyond CD19 CAR-T cells in lymphoma	8
Editorial overview: The life and times of peptide-MHC	8
Editorial Board	8
Editorial overview: Communities in immune cell signaling	8
TACI deficiency — a complex system out of balance	8
Antibody glycosylation directs innate and adaptive immune collaboration	8
Regulation of myeloid-cell activation	7
Patterns of bacterial viability governing noncanonical inflammasome activation	7
Imaging cytomegalovirus infection and ensuing immune responses	7
Functional heterogeneity in the memory B-cell response	7
Tissue-specific proteasomes in generation of MHC class I peptides and CD8+ T cells	7
Ubiquitination and cell-autonomous immunity	7
Mechanisms for control of skin immune function by the microbiome	7
Innate sensing of mRNA vaccines	7
Role of type-I and type-III interferons in gastrointestinal homeostasis and pathogenesis	7
Friendly fire: recognition of self by the innate immune system	7
The role of allergen-specific regulatory T cells in the control of allergic disease	7
Membrane cofactor protein (MCP; CD46): deficiency states and pathogen connections	7
Humoral immune defense of the central nervous system	7
Classical- and bioconjugate vaccines: comparison of the structural properties and immunological response	7
Cell entry and innate sensing shape adaptive immune responses to adenovirus-based vaccines	7
Decoding the neuroimmune axis in the atopic march: mechanisms and implications	7
Human MALT1 deficiency and predisposition to infections	7
Signals governing monocyte differentiation during inflammation	6
Z-form nucleic acid-binding protein 1 (ZBP1) as a sensor of viral and cellular Z-RNAs: walking the razor's edge	6
T-bethighCD21low B cells: the need to unify our understanding of a distinct B cell population in health and disease	6
Inborn errors of IL-6 family cytokine responses	6
ERBIN and phosphoglucomutase 3 deficiency	6
Dynamics of MHC-I molecules in the antigen processing and presentation pathway	6
Regulation of host/pathogen interactions in the gastrointestinal tract by type I and III interferons	6
Venus flytrap or pas de trois? The dynamics of MHC class I molecules	6
New insights into B cells as antigen presenting cells	6
Inherited human ZNF341 deficiency	6
Trogocytosis and cross-dressing in antigen presentation	6
Bioinspired vaccines to enhance MHC class-I antigen cross-presentation	6
Beyond natural biology: rewiring cellular networks to study innate immunity	6
Conformational sensing of major histocompatibility complex (MHC) class I molecules by immune receptors and intracellular assembly factors	6
Immunological scars after cure of hepatitis C virus infection: Long‐HepC?	6
Elevated IgE from attenuated CARD11 signaling: lessons from atopic mice and humans	6