OOIR: Observatory of International Research

Papers

(The TQCC of Current Opinion in Immunology is 13. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)

Article	Citations
Gene: environment interactions in immune and inflammatory responses to severe acute respiratory syndrome coronavirus 2 infection	268
Inflammasome activation by SARS-CoV-2 and its participation in COVID-19 exacerbation	96
Oncogenic viruses, cancer biology, and innate immunity	92
The future of vaccination in Latin America: learning from the COVID-19 pandemic	81
Revisiting the role of MRGPRX2 on hypersensitivity reactions to neuromuscular blocking drugs	70
An easy pill to swallow: oral recombinant vaccines for the 21st century	68
Mechanistic insights into epigenetic contributions to psoriasis pathogenesis and their clinical implications	67
Mycobacterial diseases in patients with inborn errors of immunity	65
Better living through chemistry: CRISPR/Cas engineered T cells for cancer immunotherapy	65
TAP-ing into the cross-presentation secrets of dendritic cells	60
AP-1 transcription factors in cytotoxic lymphocyte development and antitumor immunity	59
Principles and practical applications of structure-based vaccine design	58
Host genetics of innate immune system in infection	56
Immunological lessons from genome-wide association studies of infections	52
Metabolism and macrophages in the tumor microenvironment	48
Some thoughts about what non-mammalian jawed vertebrates are telling us about antigen processing and peptide loading of MHC molecules	48
Commander-in-chief: monocytes rally the troops for defense against aspergillosis	47
Safety switches for adoptive cell therapy	45
Can we cure Behçet syndrome?	43
Beyond the gastric epithelium — the paradox of Helicobacter pylori-induced immune responses	43
Necroptosis in immunity, tissue homeostasis, and cancer	42
Innate antiviral immunity and immunometabolism in hepatocytes	41
Regulation of MHC class II and CD86 expression by March-I in immunity and disease	40
Pharmacotherapeutic strategies to promote regulatory T cell function in autoimmunity	40
Mapping and modelling human B cell maturation in the germinal centre	39

Patterns of bacterial viability governing noncanonical inflammasome activation	39
Nutritional modulation of antitumor immunity	39
Human MALT1 deficiency and predisposition to infections	38
Antibody glycosylation directs innate and adaptive immune collaboration	38
T follicular helper cells and their impact on humoral responses during pathogen and vaccine challenge	38
Immunological scars after cure of hepatitis C virus infection: Long‐HepC?	36
Signals governing monocyte differentiation during inflammation	36
Bioinspired vaccines to enhance MHC class-I antigen cross-presentation	31
Animal models of autoimmune encephalitis	30
Can we cure bullous skin diseases?	30
Mechanistic considerations linking SARS-CoV-2 infection, inflammation, and the loss of immune tolerance	29
Monogenic autoimmunity and infectious diseases: the double-edged sword of immune dysregulation	28
Editorial overview: Recent advances in research of IgE-mediated and IgE-independent allergies, an overview	27
Editorial Board	27
Thetis cells: regulators of intestinal immune tolerance	25
Outer membrane vesicle-based intranasal vaccines	25
Harnessing IgG Fc glycosylation for clinical benefit	25
Nucleic acid triggers of autoimmunity and autoinflammation	25
Resolving adjuvant mode of action to enhance vaccine efficacy	25
Game of Omes: ribosome profiling expands the MHC-I immunopeptidome	24
Application of T cell receptor (TCR) repertoire analysis for the advancement of cancer immunotherapy	23
Powerful microscopy technologies decode spatially organized cellular networks that drive response to immunotherapy in humans	23
The increasing prevalence of autoimmunity and autoimmune diseases: an urgent call to action for improved understanding, diagnosis, treatment, and prevention	23
Bidirectional sensory neuron–immune interactions: a new vision in the understanding of allergic inflammation	23
Immune responses to Toxoplasma gondii	23
Editorial Board	23
Inborn errors of autophagy and infectious diseases	22
cGAS-like receptor-mediated immunity: the insect perspective	22
New insights into the mechanisms regulating plasma cell survival and longevity	22
Rheumatoid arthritis — the role of T cells in this complex systemic autoimmune disease	22
Killing in self-defense: proapoptotic drugs to eliminate intracellular pathogens	21
Epigenetics: the link between environmental exposures and autoimmune diseases	21
Inborn errors of human transcription factors governing IFN-γ antimycobacterial immunity	20
B cell memory of Immunoglobulin E (IgE) antibody responses in allergy	20
Neuroimmune crosstalk in the skin: a delicate balance governing inflammatory processes	20
The role of CD4 T cells in rejection of solid tumors	19
Drivers and shapers of macrophages specification in the developing brain	19
‘Can we cure IgG4-related diseases?’	19
Mechanisms and risk factors for perinatal allergic disease	19
Regulation of type I and type III interferon induction in response to pathogen sensing	19
Innate control of adaptive immunity and adaptive instruction of innate immunity: bi-directional flow of information	19
Regulation of inflammation by Interleukin-10 in the intestinal and respiratory mucosa	18
Molecular mechanisms of tumour necrosis factor signalling via TNF receptor 1 and TNF receptor 2 in the tumour microenvironment	18
Publisher's Note	17
New insights and approaches for analyses of immunopeptidomes	17
Tumor immune evasion through loss of MHC class-I antigen presentation	17
Advances and challenges in investigating B-cells via single-cell transcriptomics	17
The role of epigenetic modifications in systemic autoinflammatory diseases	17
Immunometabolic regulation of germinal centers and its implications for aging	17
ICOSL in host defense at epithelial barriers: lessons from ICOSLG deficiency	17

Major histocompatibility complex class II in the tumor microenvironment: functions of nonprofessional antigen-presenting cells	16
Intrinsic and extrinsic regulation of IgE B cell responses	16
TH17 cell immune adaptation	16
Defining the niche for stem-like CD8+ T cell formation and function	16
IFNε, IFNω and IFNλ: interferons defending the mucosa	16
Functional flexibility and plasticity in immune control of systemic Salmonella infection	15
Monogenic susceptibility to live viral vaccines	15
HyperIgE in hypomorphic recombination-activating gene defects	15
Differential signaling by type-I and type-III interferons in mucosa	15
PANoptosome signaling and therapeutic implications in infection: central role for ZBP1 to activate the inflammasome and PANoptosis	15
The thymoproteasome in shaping the CD8+ T-cell repertoire	15
Immunity to EBV as revealed by immunedeficiencies	14
Editorial overview: Tumour immunology: Engineered T cell therapy of cancer: current success and future improvements	14
Infections in the monogenic autoimmune syndrome APECED	14
Mast cell tryptases in allergic inflammation and immediate hypersensitivity	14
Curing inflammatory bowel diseases: breaking the barriers of current therapies– emerging strategies for a definitive treatment	14
Editorial overview: Communities in immune cell signaling	14
The choroid plexus in inflammatory and degenerative diseases of the central nervous system	14
Membrane cofactor protein (MCP; CD46): deficiency states and pathogen connections	14
Inherited human ZNF341 deficiency	14
Editorial overview: Special section neuroimmunology: Neuroimmune interactions in health and disease	13
Editorial Board	13
The role of intestinal bacteria in promoting tolerance to food	13
Microbiota and B-1 B cell repertoire development in mice	13
Innate immune sensing by epithelial barriers	13
Inflammasomes and their role in PANoptosomes	13
T follicular helper cells in food allergy	13
Human inborn errors of immunity to oncogenic viruses	13