OOIR: Observatory of International Research

Papers

(The TQCC of Current Opinion in Immunology is 12. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
Gene: environment interactions in immune and inflammatory responses to severe acute respiratory syndrome coronavirus 2 infection	425
TAP-ing into the cross-presentation secrets of dendritic cells	109
Oncogenic viruses, cancer biology, and innate immunity	106
AP-1 transcription factors in cytotoxic lymphocyte development and antitumor immunity	91
Mechanistic insights into epigenetic contributions to psoriasis pathogenesis and their clinical implications	83
Inflammasome activation by SARS-CoV-2 and its participation in COVID-19 exacerbation	70
An easy pill to swallow: oral recombinant vaccines for the 21st century	63
Can juvenile idiopathic arthritis be cured?	63
Principles and practical applications of structure-based vaccine design	59
T cells in Sjögren’s disease: update on their role in salivary gland pathogenesis and treatment	58
The future of vaccination in Latin America: learning from the COVID-19 pandemic	57
B cell–targeted therapies in autoimmune skin disease: current advances and challenges	56
Complement in antiphospholipid syndrome, time to target?	55
Nutritional modulation of antitumor immunity	55
Metabolism and macrophages in the tumor microenvironment	54
Neuropsychiatric lupus: a myriad of symptoms requires a myriad of models	51
Can sarcoidosis be cured?	46
Regulation of MHC class II and CD86 expression by March-I in immunity and disease	46
Commander-in-chief: monocytes rally the troops for defense against aspergillosis	39
Innate antiviral immunity and immunometabolism in hepatocytes	33
Some thoughts about what non-mammalian jawed vertebrates are telling us about antigen processing and peptide loading of MHC molecules	33
Beyond the gastric epithelium — the paradox of Helicobacter pylori-induced immune responses	31
The epidermal immune microenvironment plays a central role in the pathogenesis of psoriasis	31
Can we cure Behçet syndrome?	31
Necroptosis in immunity, tissue homeostasis, and cancer	31

Pharmacotherapeutic strategies to promote regulatory T cell function in autoimmunity	31
Immunological scars after cure of hepatitis C virus infection: Long‐HepC?	29
Mapping and modelling human B cell maturation in the germinal centre	29
Patterns of bacterial viability governing noncanonical inflammasome activation	28
Can we cure bullous skin diseases?	28
The power of genetics in decoding Sjögren’s disease: current status and future development	27
Animal models of autoimmune encephalitis	27
Implication of epigenetic factors in development and recurrence of psoriasis	27
Mechanistic considerations linking SARS-CoV-2 infection, inflammation, and the loss of immune tolerance	27
Bioinspired vaccines to enhance MHC class-I antigen cross-presentation	26
Editorial Board	26
Editorial Board	25
Outer membrane vesicle-based intranasal vaccines	25
Resolving adjuvant mode of action to enhance vaccine efficacy	24
Thetis cells: regulators of intestinal immune tolerance	24
Immune responses to Toxoplasma gondii	23
Can we cure antiphospholipid syndrome?	23
Game of Omes: ribosome profiling expands the MHC-I immunopeptidome	23
Nucleic acid triggers of autoimmunity and autoinflammation	22
The increasing prevalence of autoimmunity and autoimmune diseases: an urgent call to action for improved understanding, diagnosis, treatment, and prevention	21
Harnessing IgG Fc glycosylation for clinical benefit	21
Powerful microscopy technologies decode spatially organized cellular networks that drive response to immunotherapy in humans	20
HLA-B27 as a potential target for the cure of axial spondyloarthritis	20
New insights into the mechanisms regulating plasma cell survival and longevity	20
New autoantibodies in Sjögren's disease	20
Treating sarcoidosis: when less is more	20
A throwback on 25 years in pannexin research	20
Editorial Board	19
Epigenetics: the link between environmental exposures and autoimmune diseases	19
Killing in self-defense: proapoptotic drugs to eliminate intracellular pathogens	19
Editorial Board	19
Neuroimmune crosstalk in the skin: a delicate balance governing inflammatory processes	18
Inborn errors of human transcription factors governing IFN-γ antimycobacterial immunity	17
‘Can we cure IgG4-related diseases?’	17
Metabolomic signaling in sarcoidosis pathogenesis	17
B cell memory of Immunoglobulin E (IgE) antibody responses in allergy	17
Drivers and shapers of macrophages specification in the developing brain	17
Intracellular complement in monocytes and macrophages: emerging roles	17
Rheumatoid arthritis — the role of T cells in this complex systemic autoimmune disease	17
Can we cure lupus?	17
Multiple sclerosis: a disease or a syndrome?	16
Tumor immune evasion through loss of MHC class-I antigen presentation	16
Regulation of inflammation by Interleukin-10 in the intestinal and respiratory mucosa	16
A critical look at animal and cellular models in autoinflammatory diseases	16
Molecular mechanisms of tumour necrosis factor signalling via TNF receptor 1 and TNF receptor 2 in the tumour microenvironment	16
Mechanisms and risk factors for perinatal allergic disease	16
Regulation of type I and type III interferon induction in response to pathogen sensing	16
Advances and challenges in investigating B-cells via single-cell transcriptomics	15
IFNε, IFNω and IFNλ: interferons defending the mucosa	15
The role of epigenetic modifications in systemic autoinflammatory diseases	15

Eliciting or silencing complement activation: strategies for optimizing monoclonal antibodies functions	15
Autoimmunity, epitope analysis, and molecular mimicry	15
Red blood cell alloimmunization immunogenetic risk factor	15
TH17 cell immune adaptation	14
The role of epigenetics in inflammatory memory	14
Layers of defense: protection from respiratory viruses by epithelial-intrinsic immunity	14
Functional flexibility and plasticity in immune control of systemic Salmonella infection	14
New insights and approaches for analyses of immunopeptidomes	14
Defining the niche for stem-like CD8+ T cell formation and function	14
HyperIgE in hypomorphic recombination-activating gene defects	14
Immunometabolic regulation of germinal centers and its implications for aging	14
Composite and pragmatic measures in psoriatic arthritis: bridging trials and clinical feasibility	14
Major histocompatibility complex class II in the tumor microenvironment: functions of nonprofessional antigen-presenting cells	14
PANoptosome signaling and therapeutic implications in infection: central role for ZBP1 to activate the inflammasome and PANoptosis	14
Challenges in diagnosis of sarcoidosis	14
Editorial overview: Tumour immunology: Engineered T cell therapy of cancer: current success and future improvements	13
Differential signaling by type-I and type-III interferons in mucosa	13
Curing inflammatory bowel diseases: breaking the barriers of current therapies– emerging strategies for a definitive treatment	13
Inherited human ZNF341 deficiency	13
The thymoproteasome in shaping the CD8+ T-cell repertoire	13
Addressing unmet needs in rheumatoid arthritis: the challenge of translating multi-omics into precision therapies	13
The choroid plexus in inflammatory and degenerative diseases of the central nervous system	13
Editorial Board	12
Harnessing dendritic cell diversity in cancer immunotherapy	12
Editorial overview: Special section neuroimmunology: Neuroimmune interactions in health and disease	12
Inflammation induced by lipid mediators and protein from transfusion products	12
T follicular helper cells in food allergy	12
Harnessing microglia-based cell therapies for the treatment of neurodegenerative diseases	12
Human inborn errors of type I interferon–independent intrinsic immunity in nonleukocytic cells	12
The role of intestinal bacteria in promoting tolerance to food	12