OOIR: Observatory of International Research

Papers

(The TQCC of Current Opinion in Immunology is 15. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)

Article	Citations
Gene: environment interactions in immune and inflammatory responses to severe acute respiratory syndrome coronavirus 2 infection	273
Inflammasome activation by SARS-CoV-2 and its participation in COVID-19 exacerbation	210
Oncogenic viruses, cancer biology, and innate immunity	152
AP-1 transcription factors in cytotoxic lymphocyte development and antitumor immunity	86
The future of vaccination in Latin America: learning from the COVID-19 pandemic	85
Ebola virus disease: current vaccine solutions	82
An easy pill to swallow: oral recombinant vaccines for the 21st century	73
Revisiting the role of MRGPRX2 on hypersensitivity reactions to neuromuscular blocking drugs	71
A critical review of measures of childhood vaccine confidence	67
Principles and practical applications of structure-based vaccine design	66
Better living through chemistry: CRISPR/Cas engineered T cells for cancer immunotherapy	65
TAP-ing into the cross-presentation secrets of dendritic cells	63
Mycobacterial diseases in patients with inborn errors of immunity	59
COVID-19 vaccines	59
Innate antiviral immunity and immunometabolism in hepatocytes	58
Commander-in-chief: monocytes rally the troops for defense against aspergillosis	58
Immunological lessons from genome-wide association studies of infections	57
Metabolism and macrophages in the tumor microenvironment	57
Host genetics of innate immune system in infection	53
Necroptosis in immunity, tissue homeostasis, and cancer	52
Beyond the gastric epithelium — the paradox of Helicobacter pylori-induced immune responses	51
Pharmacotherapeutic strategies to promote regulatory T cell function in autoimmunity	48
Some thoughts about what non-mammalian jawed vertebrates are telling us about antigen processing and peptide loading of MHC molecules	47
Increasing hepatitis B vaccination coverage of healthcare workers — global lessons for South Africa	46
Regulation of MHC class II and CD86 expression by March-I in immunity and disease	44

Nutritional modulation of antitumor immunity	44
Safety switches for adoptive cell therapy	42
Immunological scars after cure of hepatitis C virus infection: Long‐HepC?	41
Bioinspired vaccines to enhance MHC class-I antigen cross-presentation	40
Conformational sensing of major histocompatibility complex (MHC) class I molecules by immune receptors and intracellular assembly factors	40
Mapping and modelling human B cell maturation in the germinal centre	39
Monogenic autoimmunity and infectious diseases: the double-edged sword of immune dysregulation	38
Patterns of bacterial viability governing noncanonical inflammasome activation	38
Human MALT1 deficiency and predisposition to infections	38
Signals governing monocyte differentiation during inflammation	37
T follicular helper cells and their impact on humoral responses during pathogen and vaccine challenge	36
Antibody glycosylation directs innate and adaptive immune collaboration	36
Editorial Board	36
Harnessing IgG Fc glycosylation for clinical benefit	35
Bidirectional sensory neuron–immune interactions: a new vision in the understanding of allergic inflammation	35
Immune responses to Toxoplasma gondii	35
Editorial overview: Recent advances in research of IgE-mediated and IgE-independent allergies, an overview	35
The politics of Covid-19 vaccine confidence	34
Game of Omes: ribosome profiling expands the MHC-I immunopeptidome	34
Outer membrane vesicle-based intranasal vaccines	34
Nucleic acid triggers of autoimmunity and autoinflammation	33
Application of T cell receptor (TCR) repertoire analysis for the advancement of cancer immunotherapy	33
The increasing prevalence of autoimmunity and autoimmune diseases: an urgent call to action for improved understanding, diagnosis, treatment, and prevention	30
Resolving adjuvant mode of action to enhance vaccine efficacy	29
New insights into the mechanisms regulating plasma cell survival and longevity	28
Editorial Board	28
Powerful microscopy technologies decode spatially organized cellular networks that drive response to immunotherapy in humans	27
Killing in self-defense: proapoptotic drugs to eliminate intracellular pathogens	27
B cell memory of Immunoglobulin E (IgE) antibody responses in allergy	27
Inborn errors of autophagy and infectious diseases	26
Rheumatoid arthritis — the role of T cells in this complex systemic autoimmune disease	25
Neuroimmune crosstalk in the skin: a delicate balance governing inflammatory processes	25
Inborn errors of human transcription factors governing IFN-γ antimycobacterial immunity	24
cGAS-like receptor-mediated immunity: the insect perspective	23
Tryptophan metabolism in brain tumors — IDO and beyond	23
The role of CD4 T cells in rejection of solid tumors	23
Regulation of type I and type III interferon induction in response to pathogen sensing	22
Tumor immune evasion through loss of MHC class-I antigen presentation	22
Drivers and shapers of macrophages specification in the developing brain	22
Innate control of adaptive immunity and adaptive instruction of innate immunity: bi-directional flow of information	22
Mechanisms and risk factors for perinatal allergic disease	22
Molecular mechanisms of tumour necrosis factor signalling via TNF receptor 1 and TNF receptor 2 in the tumour microenvironment	22
Immunometabolic regulation of germinal centers and its implications for aging	21
IFNε, IFNω and IFNλ: interferons defending the mucosa	21
Publisher's Note	21
ICOSL in host defense at epithelial barriers: lessons from ICOSLG deficiency	21
Regulation of inflammation by Interleukin-10 in the intestinal and respiratory mucosa	21
TH17 cell immune adaptation	20
Major histocompatibility complex class II in the tumor microenvironment: functions of nonprofessional antigen-presenting cells	20
Advances and challenges in investigating B-cells via single-cell transcriptomics	20

New insights and approaches for analyses of immunopeptidomes	20
Monogenic susceptibility to live viral vaccines	19
PANoptosome signaling and therapeutic implications in infection: central role for ZBP1 to activate the inflammasome and PANoptosis	19
Functional flexibility and plasticity in immune control of systemic Salmonella infection	19
Defining the niche for stem-like CD8+ T cell formation and function	19
Editorial overview: BAFF family ligands and receptors – a license to live	19
Intrinsic and extrinsic regulation of IgE B cell responses	19
Differential signaling by type-I and type-III interferons in mucosa	18
HyperIgE in hypomorphic recombination-activating gene defects	18
Infections in the monogenic autoimmune syndrome APECED	18
The thymoproteasome in shaping the CD8+ T-cell repertoire	17
Editorial overview: Tumour immunology: Engineered T cell therapy of cancer: current success and future improvements	17
Immunity to EBV as revealed by immunedeficiencies	17
Membrane cofactor protein (MCP; CD46): deficiency states and pathogen connections	17
Editorial overview: Communities in immune cell signaling	17
Editorial Board	16
Mast cell tryptases in allergic inflammation and immediate hypersensitivity	16
Editorial Board	16
Inherited human ZNF341 deficiency	16
Editorial overview: Special section neuroimmunology: Neuroimmune interactions in health and disease	16
Molecular insights into metabolite antigen recognition by mucosal-associated invariant T cells	15
Microbiota and B-1 B cell repertoire development in mice	15
Microevolution of Pseudomonas aeruginosa in the airways of people with cystic fibrosis	15
T follicular helper cells in food allergy	15
The role of intestinal bacteria in promoting tolerance to food	15