OOIR: Observatory of International Research

Papers

(The TQCC of Current Opinion in Immunology is 11. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)

Article	Citations
Gene: environment interactions in immune and inflammatory responses to severe acute respiratory syndrome coronavirus 2 infection	443
Oncogenic viruses, cancer biology, and innate immunity	111
Inflammasome activation by SARS-CoV-2 and its participation in COVID-19 exacerbation	110
An easy pill to swallow: oral recombinant vaccines for the 21st century	98
T cells in Sjögren’s disease: update on their role in salivary gland pathogenesis and treatment	84
The future of vaccination in Latin America: learning from the COVID-19 pandemic	74
Can we cure primary biliary cholangitis?	64
Principles and practical applications of structure-based vaccine design	63
Mechanistic insights into epigenetic contributions to psoriasis pathogenesis and their clinical implications	59
Can juvenile idiopathic arthritis be cured?	59
AP-1 transcription factors in cytotoxic lymphocyte development and antitumor immunity	59
TAP-ing into the cross-presentation secrets of dendritic cells	59
Complement in antiphospholipid syndrome, time to target?	56
Metabolism and macrophages in the tumor microenvironment	55
Nutritional modulation of antitumor immunity	55
Neuropsychiatric lupus: a myriad of symptoms requires a myriad of models	52
Can sarcoidosis be cured?	48
The epidermal immune microenvironment plays a central role in the pathogenesis of psoriasis	46
Pharmacotherapeutic strategies to promote regulatory T cell function in autoimmunity	40
Beyond the gastric epithelium — the paradox of Helicobacter pylori-induced immune responses	37
Commander-in-chief: monocytes rally the troops for defense against aspergillosis	34
B cell–targeted therapies in autoimmune skin disease: current advances and challenges	32
Can we cure Behçet syndrome?	32
Necroptosis in immunity, tissue homeostasis, and cancer	31
Regulation of MHC class II and CD86 expression by March-I in immunity and disease	31

Innate antiviral immunity and immunometabolism in hepatocytes	31
Some thoughts about what non-mammalian jawed vertebrates are telling us about antigen processing and peptide loading of MHC molecules	30
A critical look at observational studies	29
Mapping and modelling human B cell maturation in the germinal centre	29
Immunological scars after cure of hepatitis C virus infection: Long‐HepC?	28
Implication of epigenetic factors in development and recurrence of psoriasis	28
Bioinspired vaccines to enhance MHC class-I antigen cross-presentation	27
The power of genetics in decoding Sjögren’s disease: current status and future development	27
Patterns of bacterial viability governing noncanonical inflammasome activation	27
Animal models of autoimmune encephalitis	27
Editorial Board	27
Mechanistic considerations linking SARS-CoV-2 infection, inflammation, and the loss of immune tolerance	26
Can we cure bullous skin diseases?	26
Game of Omes: ribosome profiling expands the MHC-I immunopeptidome	25
Editorial Board	25
Can we cure antiphospholipid syndrome?	24
Resolving adjuvant mode of action to enhance vaccine efficacy	24
Harnessing IgG Fc glycosylation for clinical benefit	23
Use of synthetic data, a novel paradigm for immunopathology	22
Outer membrane vesicle-based intranasal vaccines	22
Nucleic acid triggers of autoimmunity and autoinflammation	21
Immune responses to Toxoplasma gondii	21
The increasing prevalence of autoimmunity and autoimmune diseases: an urgent call to action for improved understanding, diagnosis, treatment, and prevention	21
Thetis cells: regulators of intestinal immune tolerance	21
HLA-B27 as a potential target for the cure of axial spondyloarthritis	20
Editorial Board	20
A throwback on 25 years in pannexin research	20
Powerful microscopy technologies decode spatially organized cellular networks that drive response to immunotherapy in humans	20
Editorial Board	20
Killing in self-defense: proapoptotic drugs to eliminate intracellular pathogens	20
New autoantibodies in Sjögren's disease	19
Inborn errors of human transcription factors governing IFN-γ antimycobacterial immunity	19
Treating sarcoidosis: when less is more	19
Rheumatoid arthritis — the role of T cells in this complex systemic autoimmune disease	19
B cell memory of Immunoglobulin E (IgE) antibody responses in allergy	18
Epigenetics: the link between environmental exposures and autoimmune diseases	18
Neuroimmune crosstalk in the skin: a delicate balance governing inflammatory processes	18
Intracellular complement in monocytes and macrophages: emerging roles	18
New insights into the mechanisms regulating plasma cell survival and longevity	18
A critical look at animal and cellular models in autoinflammatory diseases	17
Clinical trials and new therapies in Sjögren’s disease	17
Metabolomic signaling in sarcoidosis pathogenesis	17
Won’t you be my neighbor? Control of the immune response by stromal and immune cell microenvironments within the lymph node	17
Can we cure lupus?	17
Multiple sclerosis: a disease or a syndrome?	16
Drivers and shapers of macrophages specification in the developing brain	16
Regulation of type I and type III interferon induction in response to pathogen sensing	16
Targeting synovial fibroblast KCa1.1 channels in rheumatoid arthritis	16
Mechanisms and risk factors for perinatal allergic disease	16
Immune dyshomeostasis in lifestyle-associated diseases: a new paradigm for personalized medicine and prevention	16

Regulation of inflammation by Interleukin-10 in the intestinal and respiratory mucosa	15
TH17 cell immune adaptation	15
Molecular mechanisms of tumour necrosis factor signalling via TNF receptor 1 and TNF receptor 2 in the tumour microenvironment	15
Eliciting or silencing complement activation: strategies for optimizing monoclonal antibodies functions	15
Defining the niche for stem-like CD8+ T cell formation and function	15
The role of epigenetics in inflammatory memory	15
Tumor immune evasion through loss of MHC class-I antigen presentation	15
Red blood cell alloimmunization immunogenetic risk factor	15
Challenges in diagnosis of sarcoidosis	15
Immunometabolic regulation of germinal centers and its implications for aging	15
‘Can we cure IgG4-related diseases?’	15
IFNε, IFNω and IFNλ: interferons defending the mucosa	15
Why we need to maintain a critical view on big data and artificial intelligence predictions	14
New insights and approaches for analyses of immunopeptidomes	14
Advances and challenges in investigating B-cells via single-cell transcriptomics	14
Composite and pragmatic measures in psoriatic arthritis: bridging trials and clinical feasibility	14
Autoimmunity, epitope analysis, and molecular mimicry	14
The role of epigenetic modifications in systemic autoinflammatory diseases	14
Major histocompatibility complex class II in the tumor microenvironment: functions of nonprofessional antigen-presenting cells	14
PANoptosome signaling and therapeutic implications in infection: central role for ZBP1 to activate the inflammasome and PANoptosis	14
Layers of defense: protection from respiratory viruses by epithelial-intrinsic immunity	13
The choroid plexus in inflammatory and degenerative diseases of the central nervous system	13
Functional flexibility and plasticity in immune control of systemic Salmonella infection	13
The thymoproteasome in shaping the CD8+ T-cell repertoire	13
HyperIgE in hypomorphic recombination-activating gene defects	13
Differential signaling by type-I and type-III interferons in mucosa	13
Curing inflammatory bowel diseases: breaking the barriers of current therapies– emerging strategies for a definitive treatment	12
Inherited human ZNF341 deficiency	12
Addressing unmet needs in rheumatoid arthritis: the challenge of translating multi-omics into precision therapies	12
Editorial overview: Tumour immunology: Engineered T cell therapy of cancer: current success and future improvements	12
Molecular insights into metabolite antigen recognition by mucosal-associated invariant T cells	11
Human inborn errors of type I interferon–independent intrinsic immunity in nonleukocytic cells	11
Microbiota and B-1 B cell repertoire development in mice	11
Editorial Board	11
Local complement inhibition by selective precision-targeted therapies	11
The role of intestinal bacteria in promoting tolerance to food	11
Editorial overview: Special section neuroimmunology: Neuroimmune interactions in health and disease	11
Mpox virus immunology: exploring links to autoimmune diseases	11