OOIR: Observatory of International Research

Papers

(The TQCC of Current Opinion in Immunology is 14. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Editorial overview: Framing the logic of type 2 immunity	264
More X’s, more problems: how contributions from the X chromosomes enhance female predisposition for autoimmunity	182
Animal models of shigellosis: a historical overview	141
Mycobacterial diseases in patients with inborn errors of immunity	84
The future of vaccination in Latin America: learning from the COVID-19 pandemic	82
MITA/STING-mediated antiviral immunity and autoimmunity: the evolution, mechanism, and intervention	72
Editorial Board	70
Better living through chemistry: CRISPR/Cas engineered T cells for cancer immunotherapy	66
Publisher's Note	61
Publisher's Note	59
CD1 displays its own negative regulators	58
Editorial Board	58
Principles of bacterial innate immunity against viruses	57
Therapeutic induction of tolerogenic dendritic cells via aryl hydrocarbon receptor signaling	56
Humoral immunity at the brain borders in homeostasis	55
Genome and population dynamics during chronic infection with Helicobacter pylori	55
The signal transducer and activator of transcription 3 at the center of the causative gene network of the hyper-IgE syndrome	54
Structure–function of type I and III interferons	52
ILC2s – development, divergence, dispersal	50
The value of vaccines	48
Gene: environment interactions in immune and inflammatory responses to severe acute respiratory syndrome coronavirus 2 infection	44
Autoimmunity, IgE and FcεRI-bearing cells	43
ICOSL in host defense at epithelial barriers: lessons from ICOSLG deficiency	43
Immunology and microbiology: how do they affect social cognition and emotion recognition?	43
A critical review of measures of childhood vaccine confidence	43

Functional heterogeneity and adaptation of naive T cells in response to tonic TCR signals	43
Revisiting the role of MRGPRX2 on hypersensitivity reactions to neuromuscular blocking drugs	40
Candidiasis in patients with APS-1: low IL-17, high IFN-γ, or both?	39
Principles and practical applications of structure-based vaccine design	38
Changing the landscape of tumor immunology: novel tools to examine T cell specificity	37
New insights and approaches for analyses of immunopeptidomes	37
Defining the niche for stem-like CD8+ T cell formation and function	36
Oncogenic viruses, cancer biology, and innate immunity	36
Mitochondrial reactive oxygen species: double agents in Mycobacterium tuberculosis infection	35
Imaging the T-cell receptor: new approaches, new insights	35
Nasal vaccines for pertussis	35
IFNε, IFNω and IFNλ: interferons defending the mucosa	34
Help me help you: emerging concepts in T follicular helper cell differentiation, identity, and function	33
Immunometabolic regulation of germinal centers and its implications for aging	33
B cells spatial organization defines their phenotype and function in cancer “Tell me with whom you consort, and I will tell you who you are” ― Goethe	33
The role of interferon in the thymus	33
Carbohydrate metabolism in supporting and regulating neutrophil effector functions	33
Chemokines that govern T cell activity in tumors	33
Discovering mechanisms of macrophage tissue infiltration with Drosophila	31
Host-encoded antivirulence defenses: host physiologies teach pathogens to play nice	31
AP-1 transcription factors in cytotoxic lymphocyte development and antitumor immunity	30
Fuelling B cells: dynamic regulation of B cell metabolism	30
Microbiome modulation of antigen presentation in tolerance and inflammation	29
The path ahead for understanding Toll-like receptor-driven systemic autoimmunity	28
Molecular mechanisms regulating T helper 2 cell differentiation and function	27
Molecular regulation and dysregulation of T follicular helper cells – learning from inborn errors of immunity	27
Major histocompatibility complex class II in the tumor microenvironment: functions of nonprofessional antigen-presenting cells	26
Get into the groove! The influence of TAPBPR on cargo selection	25
TAP-ing into the cross-presentation secrets of dendritic cells	25
T cell immunity to cytomegalovirus infection	24
Recent progress in type 1 classical dendritic cell cross-presentation - cytosolic, vacuolar, or both?	24
Why TAPBPR? Implications of an additional player in MHC class I peptide presentation	24
Tissue-resident CD8 T cells in central nervous system inflammatory diseases: present at the crime scene and …guilty	24
BAFF receptor polymorphisms and deficiency in humans	23
TH17 cell immune adaptation	23
Peptide-dependent tuning of major histocompatibility complex motional properties and the consequences for cellular immunity	23
Gut microbiome-mediated regulation of neuroinflammation	23
Advances and challenges in investigating B-cells via single-cell transcriptomics	22
Immune checkpoint receptors in autoimmunity	21
Intrinsic and extrinsic regulation of IgE B cell responses	21
Cytokine-mediated STAT-dependent pathways underpinning human B-cell differentiation and function	21
COVID-19 vaccines	21
Down syndrome and type I interferon: not so simple	20
Major histocompatibility complex class I assembly within endolysosomal pathways	20
HLA variation and antigen presentation in COVID-19 and SARS-CoV-2 infection	20
Tryptophan and indole metabolism in immune regulation	20
PANoptosome signaling and therapeutic implications in infection: central role for ZBP1 to activate the inflammasome and PANoptosis	20
Trained immunity: implications for vaccination	19
Ebola virus disease: current vaccine solutions	19
Inflammasome activation by SARS-CoV-2 and its participation in COVID-19 exacerbation	19

An easy pill to swallow: oral recombinant vaccines for the 21st century	19
‘Persistent germinal center responses: slow-growing trees bear the best fruits’	18
The thymoproteasome in shaping the CD8+ T-cell repertoire	18
The choroid plexus: a command center for brain–body communication during inflammation	17
Affinity-based clonal selection in Peyer’s patches	17
Functional flexibility and plasticity in immune control of systemic Salmonella infection	17
Atypical B cells in chronic infectious diseases and systemic autoimmunity: puzzles with many missing pieces	17
Evolving concepts of host–pathobiont interactions in autoimmunity	17
There is no gene for CVID — novel monogenetic causes for primary antibody deficiency	17
Editorial overview: Indoles: very busy (and not indolent) molecules at work in immune regulation	16
Editorial overview: BAFF family ligands and receptors – a license to live	16
Editorial Board	16
Editorial overview: Nature repeating itself: conformational flexibility determines MHC class I and class II epitope selection	16
Editorial Board	16
Pharma — manufacturing: the unappreciated and overlooked indispensable skill	15
Infections in activated PI3K delta syndrome (APDS)	15
Editorial Board	15
Mechanisms encoding STAT functional diversity for context-specific inflammatory responses	15
Immunological lessons from genome-wide association studies of infections	15
Epithelial sensing in allergic disease	15
Recent insights into the mechanisms of anaphylaxis	14
Diversity of human NK cell developmental pathways defined by single-cell analyses	14
The nonclassical immune surveillance for ERAAP function	14
Nutritional modulation of antitumor immunity	14
Inborn errors of IKAROS and AIOLOS	14
Next generation immunotherapy: enhancing stemness of polyclonal T cells to improve anti-tumor activity	14
Navigating the metabolic landscape of regulatory T cells: from autoimmune diseases to tumor microenvironments	14
The actin cytoskeleton and mast cell function	14
Genetic and immunological basis of human African trypanosomiasis	14
Innate immune activation and modulatory factors of Helicobacter pylori towards phagocytic and nonphagocytic cells	14