OOIR: Observatory of International Research

Papers

(The median citation count of Platelets is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
Enhanced platelet sensitization is accompanied by increased expression of the transporter MRP4 and elevated plasma S1P levels in mild COVID-19 convalescents	78
Abnormal expansion of peripheral helper T cells in primary immune thrombocytopenia	51
How can we use proteomics to learn more about platelets?	39
Trends among platelet function, arterial calcium, and vascular function measures	38
Platelet-derived microparticles stimulated by anti-β ₂ GPI/β ₂ GPI complexes induce pyroptosis of endothelial cells in antiphospho	37
Development of an automated chemiluminescence enzyme immunoassay for the measurement of soluble C-type lectin-like receptor 2 (sCLEC-2) and molecular forms of sCLEC-2 measured in patient plasma	36
Apoptosis is one cause of thrombocytopenia in patients with high-altitude polycythemia	28
Sex-specific relationship between blood selenium levels and platelet count in a large cohort representative of the United States population	27
Platelets and open access – a new era dawns	23
Clinical features and treatment effect of HIV-associated immune thrombocytopenia—single center Ten-Years data summary	22
Dual antiplatelet therapy is associated with high α-tubulin acetylation in circulating platelets from coronary artery disease patients	22
Increased circulating platelet-derived extracellular vesicles in severe COVID-19 disease	22
Platelet-rich plasma concentrations regulate MSCs osteogenesis via MAPK/PI3K–AKT pathways to mitigate inflammatory bone loss	19
The natural anticoagulant protein S; hemostatic functions and deficiency	19
Effects of exercise on platelet reactivity after myocardial infarction: a randomized clinical trial	18
Pro106Leu MPL mutation is associated with thrombocytosis and a low risk of thrombosis, splenomegaly and marrow fibrosis	18
Recombinant human thrombopoietin (rhTPO) of different dosing regimens for refractory/relapsed primary immune thrombocytopenia: a multicenter, randomized controlled trial and pharmacokinetics study	17
European Delphi panel to build consensus on tapering and discontinuing thrombopoietin receptor agonists in immune thrombocytopenia	17
Tirofiban potentiates agonist-induced platelet activation and degranulation, despite effectively inhibiting aggregation	17
Variation in activation marker expression within the platelet population – a new parameter for evaluation of platelet flow cytometry data	17
Extracellular thiol isomerase ERp5 regulates integrin αIIbβ3 activation by inhibition of fibrinogen binding	17
Avatrombopag improves thrombocytopenia in MYH9-related disorder following eltrombopag treatment failure	16
Phosphorylation of (Ser 291) in the linker insert of Syk negatively regulates ITAM signaling in platelets	16
Recent advances in microfluidic technology of arterial thrombosis investigations	15
Apolipoprotein A-I, elevated in trauma patients, inhibits platelet activation and decreases clot strength	15

Identification of UDP-Glucuronosyltransferase mRNA in human platelets: differential levels in smokers and non-smokers	15
Inflammation modifies the platelet reactivity among thrombocytopenia patients undergoing percutaneous coronary intervention	15
In memory of Dr. Susan S. Smyth, MD/Ph.D.	14
Impact of thrombocytopenia-associated c.-118C>T and c.-140C>G ANKRD26 5’UTR variants in three-generational pedigree	14
The use of light transmission aggregometry for monitoring platelet transfusion response in a small case cohort of Glanzmann thrombasthenia patients: a hypothesis-generating study	14
Association of thromboxane generation with the bleeding events in aspirin users	13
Deep learning, 3D ultrastructural analysis reveals quantitative differences in platelet and organelle packing in COVID-19/SARSCoV2 patient-derived platelets	13
The effect of testosterone on platelet activation and inflammation in transgender men	13
Cardiometabolic risk factor burden associates with an immature platelet profile	13
Role of platelet count in a murine stasis model of deep vein thrombosis	13
A splice mutation in RASGRP2 gene in the patient with recurrent epistaxis and nasal vascular malformation	13
Neurosurgical bleeding in platelet storage pool disorder: a case report	13
miR-28-5p targeted Rap1b attenuates splenic inflammation infiltration in immune thrombocytopenia	12
Efficacy and safety of two rituximab biosimilars for treating immune thrombocytopenia: a reference-product matched study	12
The safety and efficacy of indobufen or aspirin combined with clopidogrel in patients with acute myocardial infarction after percutaneous coronary intervention	12
Application of the Cellular Thermal Shift Assay (CETSA) to validate drug target engagement in platelets	12
Evaluation of human platelet granules by structured illumination laser fluorescence microscopy	12
What can we learn from senescent platelets, their transcriptomes and proteomes?	12
Factors influencing platelet isolation: a prospective multicenter study from Western China	12
Multiple myeloma and its treatment contribute to increased platelet reactivity	11
Single-cell transcriptome deciphers key targets of thrombopoietin receptor agonists and immune microenvironment characteristics of immune thrombocytopenia	11
In vitro evaluation of platelet extracellular vesicles (PEVs) for corneal endothelial regeneration	11
Evaluating stored platelet shape change using imaging flow cytometry	11
Pilot study on cannabis-induced alterations in platelet function: implications for transfusion medicine	11
Age and outcomes following personalized antiplatelet therapy in chronic coronary syndrome patients: a post hoc analysis of the randomized PATH-PCI trial	11
Comparison of in-hospital net clinical outcomes of ticagrelor and clopidogrel in acute coronary syndrome patients stratified by CRUSADE score: findings from the CCC-ACS registry	11
Additional efficacy analysis of avatrombopag phase III data for the treatment of adults with immune thrombocytopenia	11
Deficiency of BLOS1 moderately impairs the biogenesis of platelet dense granules	10
Romiplostim for PARP inhibitor-induced thrombocytopenia in solid tumor malignancies	10
Cryopreservation affects platelet macromolecular composition over time after thawing and differently impacts on cancer cells behavior in vitro	10
A novel, quantitative clot retraction assay to evaluate platelet function	9
Appraising non-linear association between pre-diagnostic platelet counts and cancer survival outcomes: observational and genetic analysis	9
Platelet index on admission as a predictor of bacteremia in acute cholangitis: a 7-year retrospective observational study	9
Rapid isolation of mature murine primary megakaryocytes by size exclusion via filtration	9
Association between endometriosis, infertility and autoimmune antiplatelet glycoprotein VI antibodies in two patients	9
Platelet counts in HFE p.C282Y/p.C282Y and wt/wt post-screening clinical evaluation participants	9
Roles of non-coding RNA in megakaryocytopoiesis and thrombopoiesis: new target therapies in ITP	9
From reticulated platelets to immature platelet fraction: structure, function, and clinical applications	9
Adaptive immune and platelet activation during the maintenance phase of therapy in adults with B cell acute lymphoblastic leukemia	9
Alantolactone induces platelet apoptosis by activating the Akt pathway	9
New oral protease-activated receptor 4 antagonist BMS-986120: tolerability, pharmacokinetics, pharmacodynamics, and gene variant effects in humans	9
Platelet parameters for distinguishing between inherited macrothrombocytopenia and acquired thrombocytopenia: a retrospective case–control study	9
Exacerbation of immune thrombocytopenia following initial and booster vaccination with Pfizer-BioNTech COVID-19 vaccine	9
Antiplatelet effects of the CEACAM1-derived peptide QDTT	8
Genetic background of thrombocytosis in mice mimicking hereditary thrombocytosis in humans	8
Optimizing the therapeutic window of sirolimus by monitoring blood concentration for the treatment of immune thrombocytopenia	8
Platelet extracellular vesicles are efficient delivery vehicles of doxorubicin, an anti-cancer drug: preparation and in vitro characterization	8
Correlations among different platelet aggregation pathways in a group of healthy volunteers	8
Introduction of direct-acting antiviral agents alters frequencies of anti-GPIIb/IIIa antibody-producing B cells in chronic hepatitis C patients with thrombocytopenia	8
How can platelet proteomics best be used to interrogate disease?	8

Megakaryocyte phenotyping in response to SARS-CoV-2 variants	7
Whole blood platelet aggregation measurement by Multiplate™: potential diagnostic inaccuracy of correcting the results for the sample platelet count	7
Regulation of lipid metabolism: a new strategy for platelet storage	7
An oligogenic case of severe neonatal thrombocytopenia and a purportedly benign variant in GFI1B requiring reinterpretation	7
Role of the NO-GC/cGMP signaling pathway in platelet biomechanics	7
GALE variants associated with syndromic manifestations, macrothrombocytopenia, bleeding, and platelet dysfunction	6
Effect of iron supplementation on platelet count in adult patients with iron deficiency anemia	6
Decreased platelet miR-199a-5p level might lead to high on-clopidogrel platelet reactivity in patients with coronary artery disease	6
Platelet-derived extracellular vesicles play an important role in platelet transfusion therapy	6
Frequency and molecular basis of CD36 deficiency among platelet donors in Kunming, China	6
Immunological platelet transfusion refractoriness: current insights from mechanisms to therapeutics	6
Prevalence and significance of large granular lymphocytes in patients with immune thrombocytopenia	6
Alterations in platelet activity and endothelial glycocalyx biomarkers by treatment with an angiotensin converting enzyme inhibitor or an alpha-1 adrenoceptor antagonist in patients with hypertension:	6
The complementary roles of VAMP-2, -3, and -7 in platelet secretion and function	6
The potential utilization of platelet-derived extracellular vesicles in clinical treatment	6
Vaccine-induced immune thrombotic thrombocytopenia in a male after Ad26.COV2.S vaccination presenting as cerebral venous sinus thrombosis	6
C-type lectin-like receptor-2 (CLEC-2) is a key regulator of kappa-carrageenan-induced tail thrombosis model in mice	6
Platelet-derived mitochondria transfer facilitates wound-closure by modulating ROS levels in dermal fibroblasts	6
Performance evaluation of PLT-H (hybrid-channel platelet) under various interferences and application studies for platelet transfusion decisions	5
A case of acquired transient bleeding diathesis associated with acquired platelet storage pool deficiency and defective thromboxane A2 production	5
Platelet-derived extracellular vesicles promote hair follicle growth through β-catenin signaling pathway	5
Efficacy and safety of high dose recombinant human thrombopoietin in the treatment of immune thrombocytopenia	5
Light transmission aggregometry for platelet function testing: position paper on current recommendations and French proposals for accreditation	5
Thiazole orange: a complement to established methods for diagnosing inherited dense granule defects	5
Anti-GPIb/IX autoantibodies are associated with poor response to dexamethasone combined with rituximab therapy in primary immune thrombocytopenia patients	5
Differential effects of dual antiplatelet and dual antithrombotic therapy on hemostasis in chronic coronary syndrome patients: the DEFINE CCS study	5
Platelet rich fibrin as a bioactive matrix with proosteogenic and proangiogenic properties on human healthy primary cells in vitro	5
A case-control study of bleeding risk in children with 22q11.2 deletion syndrome undergoing cardiac surgery	5
Recent advances in understanding spleen tyrosine kinase (SYK) in human biology and disease, with a focus on fostamatinib	5
F11R/JAM-A: why do platelets express a molecule which is also present in tight junctions?	5
Storage of plasma-derived exosomes: evaluation of anticoagulant use and preserving temperatures	5
Exploring the morphine-platelet activity association in patients with ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention	5
Challenges in diagnosing sticky platelet syndrome using light transmission aggregometry: a scoping review	4
Assessment of whole blood platelet aggregation in patients with cirrhosis: challenges and opportunities	4
Transcriptomic and functional characterization of megakaryocytic-derived platelet-like particles: impaired aggregation and prominent anti-tumor effects	4
Signaling mechanisms of the platelet glycoprotein Ib-IX complex	4
Activation of AMPK in platelets promotes the production of offspring	4
Immune-induced thrombocytopenia by pembrolizumab: case report and review of literature	4
Recent advances on GPIb-IX-V complex	4
The NLRP3 inflammasome in platelets – form, functions, and future of the complex	4
Glycan-Lectin interactions between platelets and tumor cells drive hematogenous metastasis	4
Developing human tissue engineered arterial constructs to simulate human in vivo thrombus formation	4
The phenotype of cryopreserved platelets influences the formation of platelet-leukocyte aggregates in an in vitro model	4
Relationship between thrombocytopenia and prognosis in children with septic shock: a retrospective cohort study	4
The CalDAG-GEFI/Rap1/αIIbβ3 axis minimally contributes to accelerated platelet clearance in mice with constitutive store-operated calcium entry	4
The efficacy of platelet rich plasma on women with poor ovarian response: a systematic review and meta-analysis	4
Eltrombopag modulates the phenotypic evolution and potential immunomodulatory roles of monocytes/macrophages in immune thrombocytopenia	4
In vitro investigations of the clot formation and resolution properties of cryopreserved platelets	4
Immature platelet fraction as a prognostic marker in patients with pulmonary embolism	4
High fragmentation in platelet concentrates impacts the activation, procoagulant, and aggregatory capacity of platelets	4