Platelets

Article	Citations
High rate of extreme thrombocytosis indicates bone marrow hyperactivity and splenic dysfunction among congenital diaphragmatic hernia patients	58
Prostacyclin analogues decrease platelet aggregation but have no effect on thrombin generation, fibrin clot structure, and fibrinolysis in pulmonary arterial hypertension: PAPAYA coagulation	37
Predictive performance of different bleeding risk scores in patients with atrial fibrillation and acute coronary syndrome or undergoing percutaneous coronary intervention	33
Contributing role of mitochondrial energy metabolism on platelet adhesion, activation and thrombus formation under blood flow conditions	33
The role of miRNAs in regulation of platelet activity and related diseases - a bioinformatic analysis	28
Comparison of predictive value of risk scores for gastrointestinal bleeding in antiplatelet therapy	28
Trends among platelet function, arterial calcium, and vascular function measures	26
Development of an automated chemiluminescence enzyme immunoassay for the measurement of soluble C-type lectin-like receptor 2 (sCLEC-2) and molecular forms of sCLEC-2 measured in patient plasma	25
Platelet-derived microparticles stimulated by anti-β 2 GPI/β 2 GPI complexes induce pyroptosis of endothelial cells in antiphospho	23
How can we use proteomics to learn more about platelets?	23
Apoptosis is one cause of thrombocytopenia in patients with high-altitude polycythemia	23
Enhanced platelet sensitization is accompanied by increased expression of the transporter MRP4 and elevated plasma S1P levels in mild COVID-19 convalescents	22
Sex-specific relationship between blood selenium levels and platelet count in a large cohort representative of the United States population	20
Platelets and open access – a new era dawns	19
Chronic immune thrombocytopenia in a child with X-linked agammaglobulinemia-an uncommon phenotype	19
Crushed/chewed administration of potent P2Y12 inhibitors in ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention: Systematic review and meta-anal	18
Increased circulating platelet-derived extracellular vesicles in severe COVID-19 disease	18
The natural anticoagulant protein S; hemostatic functions and deficiency	17
Clinical features and treatment effect of HIV-associated immune thrombocytopenia—single center Ten-Years data summary	16
Bioinspired artificial platelets: past, present and future	16
Dual antiplatelet therapy is associated with high α-tubulin acetylation in circulating platelets from coronary artery disease patients	16
Pro106Leu MPL mutation is associated with thrombocytosis and a low risk of thrombosis, splenomegaly and marrow fibrosis	15
Association between megakaryocyte abnormalities on bone marrow smear and response to thrombopoietin receptor agonists in adult patients with primary immune thrombocytopenia	14
Recombinant human thrombopoietin (rhTPO) of different dosing regimens for refractory/relapsed primary immune thrombocytopenia: a multicenter, randomized controlled trial and pharmacokinetics study	13
Significance of mild thrombocytopenia in maintenance hemodialysis patients; a retrospective cohort study	13

Extracellular thiol isomerase ERp5 regulates integrin αIIbβ3 activation by inhibition of fibrinogen binding	13
Pre-operative platelet reactivity is a strong, independent predictor of bleeding complications after branched endovascular thoracoabdominal aortic aneurysm repair	13
Effects of exercise on platelet reactivity after myocardial infarction: a randomized clinical trial	13
Avatrombopag improves thrombocytopenia in MYH9-related disorder following eltrombopag treatment failure	12
Tirofiban potentiates agonist-induced platelet activation and degranulation, despite effectively inhibiting aggregation	12
Potential mechanisms involved on how systemic IgG antibodies specific to vascular endothelial growth factor (VEGF) and induced by active immunotherapy decrease platelet derived free-VEGF	12
Apolipoprotein A-I, elevated in trauma patients, inhibits platelet activation and decreases clot strength	12
European Delphi panel to build consensus on tapering and discontinuing thrombopoietin receptor agonists in immune thrombocytopenia	11
Phosphorylation of (Ser 291) in the linker insert of Syk negatively regulates ITAM signaling in platelets	11
Ion channels and ion homeostasis in the platelet and megakaryocyte	11
Variation in activation marker expression within the platelet population – a new parameter for evaluation of platelet flow cytometry data	11
Inflammation modifies the platelet reactivity among thrombocytopenia patients undergoing percutaneous coronary intervention	11
Platelet response to aspirin in UK and Irish pregnancy cohorts: a genome-wide approach	11
Identification of UDP-Glucuronosyltransferase mRNA in human platelets: differential levels in smokers and non-smokers	11
Impact of thrombocytopenia-associated c.-118C>T and c.-140C>G ANKRD26 5’UTR variants in three-generational pedigree	10
Developmental differences of in vitro cultured murine bone marrow- and fetal liver-derived megakaryocytes	10
In memory of Dr. Susan S. Smyth, MD/Ph.D.	10
Evolution of platelet activation parameters during septic shock in intensive care unit	10
Circulating microRNAs as biomarkers and mediators of platelet activation	10
A splice mutation in RASGRP2 gene in the patient with recurrent epistaxis and nasal vascular malformation	10
Potential and limitations of PKA/ PKG inhibitors for platelet studies	10
Higher body mass index raises immature platelet count: potential contribution to obesity-related thrombosis	10
Recent advances in microfluidic technology of arterial thrombosis investigations	10
Role of platelet count in a murine stasis model of deep vein thrombosis	9
Anti-PF4/polyanion antibodies in COVID-19 patients are associated with disease severity and pulmonary pathology	9
Frozen and cold-stored platelets: reconsidered platelet products	9
Deep learning, 3D ultrastructural analysis reveals quantitative differences in platelet and organelle packing in COVID-19/SARSCoV2 patient-derived platelets	9
Thrombosis and hemorrhage in myeloproliferative neoplasms: The platelet perspective	9
Factors influencing platelet isolation: a prospective multicenter study from Western China	9
Neurosurgical bleeding in platelet storage pool disorder: a case report	9
Association of thromboxane generation with the bleeding events in aspirin users	9
EloA promotes HEL polyploidization upon PMA stimulation through enhanced ERK1/2 activity	9
Early recognition of sepsis-induced coagulopathy using the C2PAC index: a ratio of soluble type C lectin-like receptor 2 (sCLEC-2) level and platelet count	9
Age and outcomes following personalized antiplatelet therapy in chronic coronary syndrome patients: a post hoc analysis of the randomized PATH-PCI trial	8
Additional efficacy analysis of avatrombopag phase III data for the treatment of adults with immune thrombocytopenia	8
What can we learn from senescent platelets, their transcriptomes and proteomes?	8
Evaluation of human platelet granules by structured illumination laser fluorescence microscopy	8
Q94 is not a selective modulator of proteinase-activated receptor 1 (PAR1) in platelets	8
Multiple myeloma and its treatment contribute to increased platelet reactivity	8
In vitro evaluation of platelet extracellular vesicles (PEVs) for corneal endothelial regeneration	8
miR-28-5p targeted Rap1b attenuates splenic inflammation infiltration in immune thrombocytopenia	8
Application of the Cellular Thermal Shift Assay (CETSA) to validate drug target engagement in platelets	8
Platelet-derived respiratory-competent mitochondria transfer to mesenchymal stem cells to promote wound healing via metabolic reprogramming	8
Efficacy and safety of two rituximab biosimilars for treating immune thrombocytopenia: a reference-product matched study	8
Thrombocytopathy vs Platelet hyper-reactivity in COVID-19: diverse pathologies, disease outcomes and therapeutic implications	8
The safety and efficacy of indobufen or aspirin combined with clopidogrel in patients with acute myocardial infarction after percutaneous coronary intervention	8
Cardiometabolic risk factor burden associates with an immature platelet profile	8
Congenital thrombocytopenia associated with a heterozygous variant in the MEIS1 gene encoding a transcription factor essential for megakaryopoiesis	8
Platelet index on admission as a predictor of bacteremia in acute cholangitis: a 7-year retrospective observational study	7
New oral protease-activated receptor 4 antagonist BMS-986120: tolerability, pharmacokinetics, pharmacodynamics, and gene variant effects in humans	7

Romiplostim for PARP inhibitor-induced thrombocytopenia in solid tumor malignancies	7
Effect of avatrombopag in the management of severe and refractory chemotherapy-induced thrombocytopenia (CIT) in patients with solid tumors	7
Alterations in platelets during SARS-CoV-2 infection	7
Evaluating stored platelet shape change using imaging flow cytometry	7
Positive correlations between plasma BPI level and MPO-DNA and S100A8/A9 in myocardial infarction	7
Roles of non-coding RNA in megakaryocytopoiesis and thrombopoiesis: new target therapies in ITP	7
Inhibition of platelet-activating factor (PAF)-induced platelet aggregation by fatty acids from human saliva	6
An oligogenic case of severe neonatal thrombocytopenia and a purportedly benign variant in GFI1B requiring reinterpretation	6
Alantolactone induces platelet apoptosis by activating the Akt pathway	6
A novel, quantitative clot retraction assay to evaluate platelet function	6
Mapping densely packed αIIbβ3 receptors in murine blood platelets with expansion microscopy	6
Platelet parameters for distinguishing between inherited macrothrombocytopenia and acquired thrombocytopenia: a retrospective case–control study	6
Mass cytometry of platelet-rich plasma: a new approach to analyze platelet surface expression and reactivity	6
From reticulated platelets to immature platelet fraction: structure, function, and clinical applications	6
Feasibility of platelet marker analysis in ischemic stroke patients and their association with one-year outcome. A pilot project within a subsample of the Stroke Induced Cardiac Failure in Mice and Me	6
Association between endometriosis, infertility and autoimmune antiplatelet glycoprotein VI antibodies in two patients	6
Correction	6
Exacerbation of immune thrombocytopenia following initial and booster vaccination with Pfizer-BioNTech COVID-19 vaccine	6
Platelet-HIV: interactions and their implications	6
Current challenges in platelet transfusion	6
Cryopreservation affects platelet macromolecular composition over time after thawing and differently impacts on cancer cells behavior in vitro	6
Appraising non-linear association between pre-diagnostic platelet counts and cancer survival outcomes: observational and genetic analysis	6
Platelet counts in HFE p.C282Y/p.C282Y and wt/wt post-screening clinical evaluation participants	6
Rapid isolation of mature murine primary megakaryocytes by size exclusion via filtration	6
Platelet extracellular vesicles are efficient delivery vehicles of doxorubicin, an anti-cancer drug: preparation and in vitro characterization	5
How can platelet proteomics best be used to interrogate disease?	5
Megakaryocyte phenotyping in response to SARS-CoV-2 variants	5
Immunological platelet transfusion refractoriness: current insights from mechanisms to therapeutics	5
The potential utilization of platelet-derived extracellular vesicles in clinical treatment	5
Nebulization with alkaline hipertonic ibuprofen induces a rapid increase in platelets circulating in COVID-19 patients but not in healthy subjects	5
Antiplatelet effects of the CEACAM1-derived peptide QDTT	5
Role of the NO-GC/cGMP signaling pathway in platelet biomechanics	5
Correlations among different platelet aggregation pathways in a group of healthy volunteers	5
Effect of iron supplementation on platelet count in adult patients with iron deficiency anemia	5
The complementary roles of VAMP-2, -3, and -7 in platelet secretion and function	5
Frequency and molecular basis of CD36 deficiency among platelet donors in Kunming, China	5
Scanning transmission X-ray microscopy study of subcellular granules in human platelets at the carbon K- and calcium L2,3-edges	5
Introduction of direct-acting antiviral agents alters frequencies of anti-GPIIb/IIIa antibody-producing B cells in chronic hepatitis C patients with thrombocytopenia	5
Optimizing the therapeutic window of sirolimus by monitoring blood concentration for the treatment of immune thrombocytopenia	5
Whole blood platelet aggregation measurement by Multiplate™: potential diagnostic inaccuracy of correcting the results for the sample platelet count	5
GALE variants associated with syndromic manifestations, macrothrombocytopenia, bleeding, and platelet dysfunction	5
Platelet-derived mitochondria transfer facilitates wound-closure by modulating ROS levels in dermal fibroblasts	5
Regulation of lipid metabolism: a new strategy for platelet storage	5
Vaccine-induced immune thrombotic thrombocytopenia in a male after Ad26.COV2.S vaccination presenting as cerebral venous sinus thrombosis	5
Neonatal platelet physiology and implications for transfusion	5
Genetic background of thrombocytosis in mice mimicking hereditary thrombocytosis in humans	5
Recent advances in understanding spleen tyrosine kinase (SYK) in human biology and disease, with a focus on fostamatinib	4
Alterations in platelet activity and endothelial glycocalyx biomarkers by treatment with an angiotensin converting enzyme inhibitor or an alpha-1 adrenoceptor antagonist in patients with hypertension:	4
A case-control study of bleeding risk in children with 22q11.2 deletion syndrome undergoing cardiac surgery	4
Performance evaluation of PLT-H (hybrid-channel platelet) under various interferences and application studies for platelet transfusion decisions	4
Differential effects of dual antiplatelet and dual antithrombotic therapy on hemostasis in chronic coronary syndrome patients: the DEFINE CCS study	4
Recent advances on GPIb-IX-V complex	4
Exploring the morphine-platelet activity association in patients with ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention	4
The role of viscoelastic testing in assessing peri-interventional platelet function and coagulation	4
Platelet-derived extracellular vesicles play an important role in platelet transfusion therapy	4
Successful treatment of acquired amegakaryocytic thrombocytopenia with eltrombopag and immunosuppressant	4
Decreased platelet miR-199a-5p level might lead to high on-clopidogrel platelet reactivity in patients with coronary artery disease	4
Anti-GPIb/IX autoantibodies are associated with poor response to dexamethasone combined with rituximab therapy in primary immune thrombocytopenia patients	4
The CalDAG-GEFI/Rap1/αIIbβ3 axis minimally contributes to accelerated platelet clearance in mice with constitutive store-operated calcium entry	4
Bleeding and mortality risk in patients implanted with mechanical prosthetic heart valves with and without thrombocytopenia. Insights from the nationwide PLECTRUM registry	4
Efficacy and safety of high dose recombinant human thrombopoietin in the treatment of immune thrombocytopenia	4
Murine models of glycoprotein Ib-IX	4
F11R/JAM-A: why do platelets express a molecule which is also present in tight junctions?	4
Prevalence and significance of large granular lymphocytes in patients with immune thrombocytopenia	4
C-type lectin-like receptor-2 (CLEC-2) is a key regulator of kappa-carrageenan-induced tail thrombosis model in mice	4
A case of acquired transient bleeding diathesis associated with acquired platelet storage pool deficiency and defective thromboxane A2 production	4
Platelet-derived extracellular vesicles promote hair follicle growth through β-catenin signaling pathway	4
Light transmission aggregometry for platelet function testing: position paper on current recommendations and French proposals for accreditation	4
Platelet rich fibrin as a bioactive matrix with proosteogenic and proangiogenic properties on human healthy primary cells in vitro	4
Storage of plasma-derived exosomes: evaluation of anticoagulant use and preserving temperatures	4
The phenotype of cryopreserved platelets influences the formation of platelet-leukocyte aggregates in an in vitro model	3
Transcriptomic and functional characterization of megakaryocytic-derived platelet-like particles: impaired aggregation and prominent anti-tumor effects	3
“Tailored” antiplatelet bridging therapy with cangrelor: moving toward personalized medicine	3
Assessment of whole blood platelet aggregation in patients with cirrhosis: challenges and opportunities	3
Glycan-Lectin interactions between platelets and tumor cells drive hematogenous metastasis	3
Clopidogrel monotherapy is associated with higher mortality risk compared to aspirin: a retrospective analysis of NHANES 1999–2018	3
First-in-human study to assess the safety, pharmacokinetics, and pharmacodynamics of BMS-986141, a novel, reversible, small-molecule, PAR4 agonist in non-Japanese and Japanese healthy participants	3
Effect of aspirin dosage on oxidative stress and platelet reactivity in patients undergoing coronary artery bypass grafting (APRICOT): randomized controlled trial	3
Developing human tissue engineered arterial constructs to simulate human in vivo thrombus formation	3
Relationship between thrombocytopenia and prognosis in children with septic shock: a retrospective cohort study	3

Eltrombopag modulates the phenotypic evolution and potential immunomodulatory roles of monocytes/macrophages in immune thrombocytopenia	3
Immune-induced thrombocytopenia by pembrolizumab: case report and review of literature	3
Signaling mechanisms of the platelet glycoprotein Ib-IX complex	3
Thrombus remodelling by reversible and irreversible P2Y 12 inhibitors	3
Finding and following: a deep learning-based pipeline for tracking platelets during thrombus formation in vivo and ex vivo	3
Activation of AMPK in platelets promotes the production of offspring	3
High fragmentation in platelet concentrates impacts the activation, procoagulant, and aggregatory capacity of platelets	3
The efficacy of platelet rich plasma on women with poor ovarian response: a systematic review and meta-analysis	3
New presentations and exacerbations of immune thrombocytopenia after coronavirus disease 2019 vaccinations: the Taiwan experience	3
Method article: anin vitroblood flow model to advance the study of platelet adhesion utilizing a damaged endothelium	3
Efficacy of platelet transfusion in cardiac surgery	3
Proteomics-wise, how similar are mouse and human platelets?	3
Akt pathway activation reduces platelet apoptosis and contributes to the increase of platelet counts in solid tumor patients	3