Platelets

Article	Citations
Platelets editorial 2022: transitioning	51
Proteomics-wise, how similar are mouse and human platelets?	37
Nebulization with alkaline hipertonic ibuprofen induces a rapid increase in platelets circulating in COVID-19 patients but not in healthy subjects	32
Thrombosis and hemorrhage in myeloproliferative neoplasms: The platelet perspective	30
Frequency and molecular basis of CD36 deficiency among platelet donors in Kunming, China	25
Cardiometabolic risk factor burden associates with an immature platelet profile	23
Effect of aspirin dosage on oxidative stress and platelet reactivity in patients undergoing coronary artery bypass grafting (APRICOT): randomized controlled trial	21
Predictive performance of different bleeding risk scores in patients with atrial fibrillation and acute coronary syndrome or undergoing percutaneous coronary intervention	20
Evaluation of human platelet granules by structured illumination laser fluorescence microscopy	20
Platelet–leukocyte interactions in the pathogenesis of viral infections	20
Effects of electret coating technology on coronary stent thrombogenicity	19
The complementary roles of VAMP-2, -3, and -7 in platelet secretion and function	18
How can we use proteomics to learn more about platelets?	18
Regulation of lipid metabolism: a new strategy for platelet storage	17
Comparison of predictive value of risk scores for gastrointestinal bleeding in antiplatelet therapy	17
Early recognition of sepsis-induced coagulopathy using the C2PAC index: a ratio of soluble type C lectin-like receptor 2 (sCLEC-2) level and platelet count	17
Factors influencing platelet isolation: a prospective multicenter study from Western China	17
The phenotype of cryopreserved platelets influences the formation of platelet-leukocyte aggregates in an in vitro model	17
Enhanced platelet sensitization is accompanied by increased expression of the transporter MRP4 and elevated plasma S1P levels in mild COVID-19 convalescents	17
What can the plasma proteome tell us about platelets (and vice versa)?	17
Molecular insights on Eltrombopag: potential mitogen stimulants, angiogenesis, and therapeutic radioprotectant through TPO-R activation	16
Effects of different doses of tirofiban combined with dual antiplatelet drugs on platelet indices, vascular endothelial function, and major adverse cardiovascular events in patients with acute ST-segm	16
First-in-human study to assess the safety, pharmacokinetics, and pharmacodynamics of BMS-986141, a novel, reversible, small-molecule, PAR4 agonist in non-Japanese and Japanese healthy participants	15
Development of an automated chemiluminescence enzyme immunoassay for the measurement of soluble C-type lectin-like receptor 2 (sCLEC-2) and molecular forms of sCLEC-2 measured in patient plasma	15
Real-life clinical practice in Spain in the setting of new drug availability for ITP treatment. A Delphi-based Spanish expert panel consensus	15

Application of the Cellular Thermal Shift Assay (CETSA) to validate drug target engagement in platelets	14
Activation of AMPK in platelets promotes the production of offspring	14
Finding and following: a deep learning-based pipeline for tracking platelets during thrombus formation in vivo and ex vivo	14
New αIIbβ3 variants in 28 Turkish Glanzmann patients; structural hypothesis for complex activation by residues variations in I-EGF domains	14
Platelet-derived mitochondria transfer facilitates wound-closure by modulating ROS levels in dermal fibroblasts	13
What can we learn from senescent platelets, their transcriptomes and proteomes?	13
The utility of flow cytometric platelet forward scatter as an alternative to mean platelet volume	13
The potential utilization of platelet-derived extracellular vesicles in clinical treatment	13
Thrombus remodelling by reversible and irreversible P2Y 12 inhibitors	12
Immunological platelet transfusion refractoriness: current insights from mechanisms to therapeutics	12
The plant hormone abscisic acid stimulates megakaryocyte differentiation from human iPSCs in vitro	12
Contributing role of mitochondrial energy metabolism on platelet adhesion, activation and thrombus formation under blood flow conditions	11
GALE variants associated with syndromic manifestations, macrothrombocytopenia, bleeding, and platelet dysfunction	11
Enrichment of plasma in platelets and extracellular vesicles by the counterflow to erythrocyte settling	11
A platelet lipidomics signature in patients with COVID-19	11
EDTA stabilizes the concentration of platelet-derived extracellular vesicles during blood collection and handling	10
High rate of extreme thrombocytosis indicates bone marrow hyperactivity and splenic dysfunction among congenital diaphragmatic hernia patients	10
Trends among platelet function, arterial calcium, and vascular function measures	9
EloA promotes HEL polyploidization upon PMA stimulation through enhanced ERK1/2 activity	9
Apoptosis is one cause of thrombocytopenia in patients with high-altitude polycythemia	9
Evidence for a PI3-kinase independent pathway in the regulation of Rap1b activation downstream of the P2Y12 receptor in platelets	9
Immature platelets and cardiovascular events in patients with stable coronary artery disease	9
Prostacyclin analogues decrease platelet aggregation but have no effect on thrombin generation, fibrin clot structure, and fibrinolysis in pulmonary arterial hypertension: PAPAYA coagulation	9
Akt pathway activation reduces platelet apoptosis and contributes to the increase of platelet counts in solid tumor patients	9
Stability and utility of flow cytometric platelet activation tests: A modality to bridge the gap between diagnostic demand and supply	8
Platelets enhance CD4+ central memory T cell responses via platelet factor 4-dependent mitochondrial biogenesis and cell proliferation	8
Thrombocytopenia and platelet count recovery in patients with sepsis-3: a retrospective observational study	8
Injectable platelet-rich fibrin positively regulates osteogenic differentiation of stem cells from implant hole via the ERK1/2 pathway	8
Platelet-derived microparticles stimulated by anti-β 2 GPI/β 2 GPI complexes induce pyroptosis of endothelial cells in antiphospho	8
Anti-PF4/polyanion antibodies in COVID-19 patients are associated with disease severity and pulmonary pathology	8
Efficacy of platelet transfusion in cardiac surgery	8
Frozen and cold-stored platelets: reconsidered platelet products	8
Comparison of the effects of platelet concentrates produced by high and low-speed centrifugation protocols on the healing of critical-size defects in rat calvaria: a microtomographic and histomorphome	8
The role of miRNAs in regulation of platelet activity and related diseases - a bioinformatic analysis	8
Effect of iron supplementation on platelet count in adult patients with iron deficiency anemia	8
Neonatal platelet physiology and implications for transfusion	8
Developing human tissue engineered arterial constructs to simulate human in vivo thrombus formation	8
The safety and efficacy of indobufen or aspirin combined with clopidogrel in patients with acute myocardial infarction after percutaneous coronary intervention	8
Platelet-derived extracellular vesicles play an important role in platelet transfusion therapy	7
Treatment of immune thrombocytopenia with hetrombopag olamine tablets in a Kabuki syndrome patient with new KMT2D mutations	7
Scanning transmission X-ray microscopy study of subcellular granules in human platelets at the carbon K- and calcium L2,3-edges	7
C-type lectin-like receptor-2 (CLEC-2) is a key regulator of kappa-carrageenan-induced tail thrombosis model in mice	7
Platelets and open access – a new era dawns	7
Successful mRNA SARS-Cov-2 vaccine rechallenge after a first episode of immune thrombocytopenic purpura	7
Vaccine-induced immune thrombotic thrombocytopenia in a male after Ad26.COV2.S vaccination presenting as cerebral venous sinus thrombosis	7
Anti-GPVI (HY101) activates platelets in a multicolor flow cytometry panel	7
Healthy pediatric platelets are moderately hyporeactive in comparison with adults’ platelets	7
Predictors of high platelet reactivity assessed by Multiple Electrode Aggregometry in healthy individuals ‒ the role of leukocyte count	7
Editorial: structure–function relationships of tyrosine kinase- and tyrosine phosphatase-linked receptors in platelets and megakaryocytes	7
Congenital thrombocytopenia associated with a heterozygous variant in the MEIS1 gene encoding a transcription factor essential for megakaryopoiesis	7

Efficacy and safety of two rituximab biosimilars for treating immune thrombocytopenia: a reference-product matched study	7
Sex-specific relationship between blood selenium levels and platelet count in a large cohort representative of the United States population	7
Tailoring antiplatelet therapy in older patients with coronary artery disease	7
ALB–PRF facilitates chondrogenesis by promoting chondrocytes migration, proliferation and differentiation	6
In vitro evaluation of platelet extracellular vesicles (PEVs) for corneal endothelial regeneration	6
The natural anticoagulant protein S; hemostatic functions and deficiency	6
Distinct phenotypes of platelet, monocyte, and neutrophil activation occur during the acute and convalescent phase of COVID-19	6
Human Platelets and Influenza Virus: Internalization and Platelet Activation	6
Management of a twin pregnancy patient with Glanzmann thrombasthenia might be caused by a novel ITGA2B gene mutation (c.2822G>A): a case report and family investigati	6
Gravity sedimentation reveals functionally and morphologically different platelets in human blood	6
Branched endovascular aortic aneurysm repair decreases platelet reactivity and platelet-rich thrombus formation – a prospective, cohort study	6
Edi(torial) 2024: action plan for change and new initiatives	6
The utility of platelet activation biomarkers in thrombotic microangiopathies	6
Increased circulating platelet-derived extracellular vesicles in severe COVID-19 disease	6
A case-control study of bleeding risk in children with 22q11.2 deletion syndrome undergoing cardiac surgery	6
Analysis of clinical characteristics and treatment efficacy in two pediatric cases of ANKRD26 -related thrombocytopenia	5
Dual antiplatelet therapy is associated with high α-tubulin acetylation in circulating platelets from coronary artery disease patients	5
Atorvastatin-mediated inhibition of prenylation of Rab27b and Rap1a in platelets attenuates their prothrombotic capacity and modulates clot structure	5
Mutated JAK2 signal transduction in human induced pluripotent stem cell (iPSC)-derived megakaryocytes	5
Chronic immune thrombocytopenia in a child with X-linked agammaglobulinemia-an uncommon phenotype	5
Measurement of platelet thrombus formation in patients following severe thermal injury	5
Q94 is not a selective modulator of proteinase-activated receptor 1 (PAR1) in platelets	5
Clinical features and treatment effect of HIV-associated immune thrombocytopenia—single center Ten-Years data summary	5
Crushed/chewed administration of potent P2Y12 inhibitors in ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention: Systematic review and meta-anal	5
The voltage-gated K+ channel Kv1.3 modulates platelet motility and α2β1 integrin-dependent adhesion to collagen	5
Platelet aggregation responses to Salmonella Typhimurium are determined by host anti- Salmonella antibody levels	5
Performance evaluation of PLT-H (hybrid-channel platelet) under various interferences and application studies for platelet transfusion decisions	5
Prevalence and natural history of variants in the ANKRD26 gene: a short review and update of reported cases	5
In vitro studies on the effects of cryopreserved platelet-rich plasma on cells related to wound healing	5
Inhibition of Src but not Syk causes weak reversal of GPVI-mediated platelet aggregation measured by light transmission aggregometry	5
The prospects of microphysiological systems in modeling platelet pathophysiology in cancer	5
Special review series: provocative questions in platelet omics studies	5
Prevalence and significance of large granular lymphocytes in patients with immune thrombocytopenia	5
Humanized mouse models for inherited thrombocytopenia studies	5
Successful treatment of acquired amegakaryocytic thrombocytopenia with eltrombopag and immunosuppressant	5
Extracellular thiol isomerase ERp5 regulates integrin αIIbβ3 activation by inhibition of fibrinogen binding	4
Platelet-derived respiratory-competent mitochondria transfer to mesenchymal stem cells to promote wound healing via metabolic reprogramming	4
Decreased platelet miR-199a-5p level might lead to high on-clopidogrel platelet reactivity in patients with coronary artery disease	4
Prospective assessment of platelet function in patients undergoing elective resection of glioblastoma multiforme	4
α-Synuclein is the major platelet isoform but is dispensable for activation, secretion, and thrombosis	4
What can we learn from the platelet lipidome?	4
Association between megakaryocyte abnormalities on bone marrow smear and response to thrombopoietin receptor agonists in adult patients with primary immune thrombocytopenia	4
An optimized agonist peptide of protease-activated receptor 4 and its use in a validated platelet-aggregation assay	4
Pro106Leu MPL mutation is associated with thrombocytosis and a low risk of thrombosis, splenomegaly and marrow fibrosis	4
Identification of apolipoprotein A-I as a target of platelet tyrosine kinases	4
ADP-induced platelet reactivity and bleeding events in patients with acute myocardial infarction complicated by cardiogenic shock	4
Age and outcomes following personalized antiplatelet therapy in chronic coronary syndrome patients: a post hoc analysis of the randomized PATH-PCI trial	4
Management of immune thrombotic thrombocytopenic purpura with caplacizumab: a Canadian, single-centre, real-world experience	4
Effects of platelets activated by different agonists on fibrin formation and thrombin generation	4
Recent advances in understanding spleen tyrosine kinase (SYK) in human biology and disease, with a focus on fostamatinib	4
Platelet mass cytometry reveals dysregulation of prothrombotic pathways in essential thrombocythemia	4
Additional efficacy analysis of avatrombopag phase III data for the treatment of adults with immune thrombocytopenia	4
Irradiation of platelets in transfusion medicine: risk and benefit judgments	4
Pre-operative platelet reactivity is a strong, independent predictor of bleeding complications after branched endovascular thoracoabdominal aortic aneurysm repair	4
Recombinant human thrombopoietin (rhTPO) of different dosing regimens for refractory/relapsed primary immune thrombocytopenia: a multicenter, randomized controlled trial and pharmacokinetics study	4
Successful use of a second course of caplacizumab in relapsed thrombotic thrombocytopenic purpura	4
Bioinspired artificial platelets: past, present and future	4
Alterations in platelet activity and endothelial glycocalyx biomarkers by treatment with an angiotensin converting enzyme inhibitor or an alpha-1 adrenoceptor antagonist in patients with hypertension:	4
Multiple myeloma and its treatment contribute to increased platelet reactivity	4
Building platelet phenotypes: Diaphanous-related formin 1 (DIAPH1)-related disorder	4
A case of acquired transient bleeding diathesis associated with acquired platelet storage pool deficiency and defective thromboxane A2 production	4
Aquaporins in platelet function	4
Gender-related differences in changes of estimated bleeding risk in patients on dual antiplatelet therapy: the RE-SCORE multicenter prospective registry	4
Platelet counts in HFE p.C282Y/p.C282Y and wt/wt post-screening clinical evaluation participants	3
Thrombosis in Covid-19 and non-Covid-19 pneumonia: role of platelets	3
Anti-GPIb/IX autoantibodies are associated with poor response to dexamethasone combined with rituximab therapy in primary immune thrombocytopenia patients	3
Treatment inequity in antiplatelet therapy for ischaemic heart disease in patients with advanced chronic kidney disease: releasing the evidence vacuum	3
F11R/JAM-A: why do platelets express a molecule which is also present in tight junctions?	3
Mind the gap: connexins and pannexins in platelet function	3
Janus kinase inhibitors ruxolitinib and baricitinib impair glycoprotein-VI mediated platelet function	3
Combining human platelet proteomes and transcriptomes: possibilities and challenges	3
Safety and efficacy of low-dose ticagrelor in Chinese patients with acute coronary syndrome undergoing percutaneous coronary intervention	3
Evaluating stored platelet shape change using imaging flow cytometry	3
Alterations in platelets during SARS-CoV-2 infection	3
Peripheral versus central venous blood sampling does not influence the assessment of platelet activation in cirrhosis	3
Cryopreservation affects platelet macromolecular composition over time after thawing and differently impacts on cancer cells behavior in vitro	3
Platelet index on admission as a predictor of bacteremia in acute cholangitis: a 7-year retrospective observational study	3
Editorial: special review series on viruses and platelets	3
Significance of mild thrombocytopenia in maintenance hemodialysis patients; a retrospective cohort study	3
Why do platelets express K+ channels?	3

Feasibility of a mean platelet volume standard: an international council for standardization in hematology (ICSH) inter-laboratory study	3
Platelets after burn injury – hemostasis and beyond	3
Exploration of risk factors of platelet transfusion refractoriness and its impact on the prognosis of hematopoietic stem cell transplantation: a retrospective study of patients with hematological dise	3
Pathogen inactivation of platelets for transfusion	3
Potential mechanisms involved on how systemic IgG antibodies specific to vascular endothelial growth factor (VEGF) and induced by active immunotherapy decrease platelet derived free-VEGF	3
GPIb-IX-V and platelet clearance	3
Association between endometriosis, infertility and autoimmune antiplatelet glycoprotein VI antibodies in two patients	3
Safety, tolerance, pharmacokinetic and pharmacodynamic properties of thrombopoietin mimetic peptide for injection in Chinese healthy volunteers: a randomized, placebo-controlled, double-blind study	3
Effects of exercise on platelet reactivity after myocardial infarction: a randomized clinical trial	3
Philadelphia-positive acute lymphoblastic leukemia in a case of MPL p.(W515L) variant essential thrombocythemia: case report and literature review	3
Thrombocytopathy vs Platelet hyper-reactivity in COVID-19: diverse pathologies, disease outcomes and therapeutic implications	3
Helicobacter pylori protein that binds to and activates platelet specifically reacts with sera of H. pylori-associated chronic immune thrombocytopenia	3
Flow cytometry identifies an early stage of platelet apoptosis produced by agonists of the P2X1 and P2X7 receptors	3
Avatrombopag improves thrombocytopenia in MYH9-related disorder following eltrombopag treatment failure	3
Reply to “Peripheral versus central venous blood sampling does not influence the assessment of platelet activation in cirrhosis”	3
New oral protease-activated receptor 4 antagonist BMS-986120: tolerability, pharmacokinetics, pharmacodynamics, and gene variant effects in humans	3