OOIR: Observatory of International Research

Papers

(The median citation count of Platelets is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
Enhanced platelet sensitization is accompanied by increased expression of the transporter MRP4 and elevated plasma S1P levels in mild COVID-19 convalescents	81
Abnormal expansion of peripheral helper T cells in primary immune thrombocytopenia	58
Apoptosis is one cause of thrombocytopenia in patients with high-altitude polycythemia	43
How can we use proteomics to learn more about platelets?	40
Platelet-derived microparticles stimulated by anti-β ₂ GPI/β ₂ GPI complexes induce pyroptosis of endothelial cells in antiphospho	39
Trends among platelet function, arterial calcium, and vascular function measures	30
Development of an automated chemiluminescence enzyme immunoassay for the measurement of soluble C-type lectin-like receptor 2 (sCLEC-2) and molecular forms of sCLEC-2 measured in patient plasma	25
Dual antiplatelet therapy is associated with high α-tubulin acetylation in circulating platelets from coronary artery disease patients	24
Increased circulating platelet-derived extracellular vesicles in severe COVID-19 disease	22
Clinical features and treatment effect of HIV-associated immune thrombocytopenia—single center Ten-Years data summary	20
Sex-specific relationship between blood selenium levels and platelet count in a large cohort representative of the United States population	20
Extracellular thiol isomerase ERp5 regulates integrin αIIbβ3 activation by inhibition of fibrinogen binding	19
Platelet-rich plasma concentrations regulate MSCs osteogenesis via MAPK/PI3K–AKT pathways to mitigate inflammatory bone loss	19
The natural anticoagulant protein S; hemostatic functions and deficiency	19
Effects of exercise on platelet reactivity after myocardial infarction: a randomized clinical trial	18
Recombinant human thrombopoietin (rhTPO) of different dosing regimens for refractory/relapsed primary immune thrombocytopenia: a multicenter, randomized controlled trial and pharmacokinetics study	18
The use of light transmission aggregometry for monitoring platelet transfusion response in a small case cohort of Glanzmann thrombasthenia patients: a hypothesis-generating study	17
Phosphorylation of (Ser 291) in the linker insert of Syk negatively regulates ITAM signaling in platelets	17
European Delphi panel to build consensus on tapering and discontinuing thrombopoietin receptor agonists in immune thrombocytopenia	17
Identification of UDP-Glucuronosyltransferase mRNA in human platelets: differential levels in smokers and non-smokers	17
Impact of thrombocytopenia-associated c.-118C>T and c.-140C>G ANKRD26 5’UTR variants in three-generational pedigree	17
Inflammation modifies the platelet reactivity among thrombocytopenia patients undergoing percutaneous coronary intervention	17
Recent advances in microfluidic technology of arterial thrombosis investigations	16
In memory of Dr. Susan S. Smyth, MD/Ph.D.	16
A splice mutation in RASGRP2 gene in the patient with recurrent epistaxis and nasal vascular malformation	15

Association of thromboxane generation with the bleeding events in aspirin users	15
Deep learning, 3D ultrastructural analysis reveals quantitative differences in platelet and organelle packing in COVID-19/SARSCoV2 patient-derived platelets	15
Factors influencing platelet isolation: a prospective multicenter study from Western China	14
The effect of testosterone on platelet activation and inflammation in transgender men	14
Evaluation of human platelet granules by structured illumination laser fluorescence microscopy	14
Role of platelet count in a murine stasis model of deep vein thrombosis	14
Neurosurgical bleeding in platelet storage pool disorder: a case report	14
What can we learn from senescent platelets, their transcriptomes and proteomes?	13
Cardiometabolic risk factor burden associates with an immature platelet profile	13
The safety and efficacy of indobufen or aspirin combined with clopidogrel in patients with acute myocardial infarction after percutaneous coronary intervention	13
miR-28-5p targeted Rap1b attenuates splenic inflammation infiltration in immune thrombocytopenia	13
Efficacy and safety of two rituximab biosimilars for treating immune thrombocytopenia: a reference-product matched study	13
Application of the Cellular Thermal Shift Assay (CETSA) to validate drug target engagement in platelets	13
Multiple myeloma and its treatment contribute to increased platelet reactivity	12
Evaluating stored platelet shape change using imaging flow cytometry	12
Additional efficacy analysis of avatrombopag phase III data for the treatment of adults with immune thrombocytopenia	12
Pilot study on cannabis-induced alterations in platelet function: implications for transfusion medicine	12
In vitro evaluation of platelet extracellular vesicles (PEVs) for corneal endothelial regeneration	12
Deficiency of BLOS1 moderately impairs the biogenesis of platelet dense granules	12
Association between endometriosis, infertility and autoimmune antiplatelet glycoprotein VI antibodies in two patients	12
Age and outcomes following personalized antiplatelet therapy in chronic coronary syndrome patients: a post hoc analysis of the randomized PATH-PCI trial	12
Single-cell transcriptome deciphers key targets of thrombopoietin receptor agonists and immune microenvironment characteristics of immune thrombocytopenia	12
Comparison of in-hospital net clinical outcomes of ticagrelor and clopidogrel in acute coronary syndrome patients stratified by CRUSADE score: findings from the CCC-ACS registry	12
Platelet index on admission as a predictor of bacteremia in acute cholangitis: a 7-year retrospective observational study	11
Cryopreservation affects platelet macromolecular composition over time after thawing and differently impacts on cancer cells behavior in vitro	11
A novel, quantitative clot retraction assay to evaluate platelet function	11
Platelet counts in HFE p.C282Y/p.C282Y and wt/wt post-screening clinical evaluation participants	11
Roles of non-coding RNA in megakaryocytopoiesis and thrombopoiesis: new target therapies in ITP	11
Appraising non-linear association between pre-diagnostic platelet counts and cancer survival outcomes: observational and genetic analysis	11
Romiplostim for PARP inhibitor-induced thrombocytopenia in solid tumor malignancies	10
Platelet parameters for distinguishing between inherited macrothrombocytopenia and acquired thrombocytopenia: a retrospective case–control study	10
Alantolactone induces platelet apoptosis by activating the Akt pathway	10
Rapid isolation of mature murine primary megakaryocytes by size exclusion via filtration	10
From reticulated platelets to immature platelet fraction: structure, function, and clinical applications	9
Antiplatelet effects of the CEACAM1-derived peptide QDTT	9
Genetic background of thrombocytosis in mice mimicking hereditary thrombocytosis in humans	9
Adaptive immune and platelet activation during the maintenance phase of therapy in adults with B cell acute lymphoblastic leukemia	9
Optimizing the therapeutic window of sirolimus by monitoring blood concentration for the treatment of immune thrombocytopenia	9
How can platelet proteomics best be used to interrogate disease?	9
Whole blood platelet aggregation measurement by Multiplate™: potential diagnostic inaccuracy of correcting the results for the sample platelet count	9
Introduction of direct-acting antiviral agents alters frequencies of anti-GPIIb/IIIa antibody-producing B cells in chronic hepatitis C patients with thrombocytopenia	9
An oligogenic case of severe neonatal thrombocytopenia and a purportedly benign variant in GFI1B requiring reinterpretation	9
Role of the NO-GC/cGMP signaling pathway in platelet biomechanics	8
Effect of iron supplementation on platelet count in adult patients with iron deficiency anemia	8
Platelet extracellular vesicles are efficient delivery vehicles of doxorubicin, an anti-cancer drug: preparation and in vitro characterization	8
Regulation of lipid metabolism: a new strategy for platelet storage	8
Correlations among different platelet aggregation pathways in a group of healthy volunteers	8
GALE variants associated with syndromic manifestations, macrothrombocytopenia, bleeding, and platelet dysfunction	7
The potential utilization of platelet-derived extracellular vesicles in clinical treatment	7
Decreased platelet miR-199a-5p level might lead to high on-clopidogrel platelet reactivity in patients with coronary artery disease	7

Megakaryocyte phenotyping in response to SARS-CoV-2 variants	7
The complementary roles of VAMP-2, -3, and -7 in platelet secretion and function	7
Platelet-derived extracellular vesicles play an important role in platelet transfusion therapy	7
Frequency and molecular basis of CD36 deficiency among platelet donors in Kunming, China	7
Immunological platelet transfusion refractoriness: current insights from mechanisms to therapeutics	7
Platelet-derived mitochondria transfer facilitates wound-closure by modulating ROS levels in dermal fibroblasts	7
Exploring the morphine-platelet activity association in patients with ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention	6
Thiazole orange: a complement to established methods for diagnosing inherited dense granule defects	6
Platelet rich fibrin as a bioactive matrix with proosteogenic and proangiogenic properties on human healthy primary cells in vitro	6
A case-control study of bleeding risk in children with 22q11.2 deletion syndrome undergoing cardiac surgery	6
Prevalence and significance of large granular lymphocytes in patients with immune thrombocytopenia	6
Differential effects of dual antiplatelet and dual antithrombotic therapy on hemostasis in chronic coronary syndrome patients: the DEFINE CCS study	6
Alterations in platelet activity and endothelial glycocalyx biomarkers by treatment with an angiotensin converting enzyme inhibitor or an alpha-1 adrenoceptor antagonist in patients with hypertension:	6
Storage of plasma-derived exosomes: evaluation of anticoagulant use and preserving temperatures	6
A case of acquired transient bleeding diathesis associated with acquired platelet storage pool deficiency and defective thromboxane A2 production	6
Platelet-derived extracellular vesicles promote hair follicle growth through β-catenin signaling pathway	6
Anti-GPIb/IX autoantibodies are associated with poor response to dexamethasone combined with rituximab therapy in primary immune thrombocytopenia patients	6
C-type lectin-like receptor-2 (CLEC-2) is a key regulator of kappa-carrageenan-induced tail thrombosis model in mice	6
Recent advances in understanding spleen tyrosine kinase (SYK) in human biology and disease, with a focus on fostamatinib	6
Performance evaluation of PLT-H (hybrid-channel platelet) under various interferences and application studies for platelet transfusion decisions	6
Efficacy and safety of high dose recombinant human thrombopoietin in the treatment of immune thrombocytopenia	6
F11R/JAM-A: why do platelets express a molecule which is also present in tight junctions?	6
Light transmission aggregometry for platelet function testing: position paper on current recommendations and French proposals for accreditation	5
The CalDAG-GEFI/Rap1/αIIbβ3 axis minimally contributes to accelerated platelet clearance in mice with constitutive store-operated calcium entry	5
Relationship between thrombocytopenia and prognosis in children with septic shock: a retrospective cohort study	5
Immune-induced thrombocytopenia by pembrolizumab: case report and review of literature	5
Assessment of whole blood platelet aggregation in patients with cirrhosis: challenges and opportunities	5
High fragmentation in platelet concentrates impacts the activation, procoagulant, and aggregatory capacity of platelets	5
Challenges in diagnosing sticky platelet syndrome using light transmission aggregometry: a scoping review	5
Effect of aspirin dosage on oxidative stress and platelet reactivity in patients undergoing coronary artery bypass grafting (APRICOT): randomized controlled trial	4
Activation of AMPK in platelets promotes the production of offspring	4
In vitro investigations of the clot formation and resolution properties of cryopreserved platelets	4
The efficacy of platelet rich plasma on women with poor ovarian response: a systematic review and meta-analysis	4
Developing human tissue engineered arterial constructs to simulate human in vivo thrombus formation	4
First-in-human study to assess the safety, pharmacokinetics, and pharmacodynamics of BMS-986141, a novel, reversible, small-molecule, PAR4 agonist in non-Japanese and Japanese healthy participants	4
Clopidogrel monotherapy is associated with higher mortality risk compared to aspirin: a retrospective analysis of NHANES 1999–2018	4
Transcriptomic and functional characterization of megakaryocytic-derived platelet-like particles: impaired aggregation and prominent anti-tumor effects	4
The NLRP3 inflammasome in platelets – form, functions, and future of the complex	4
Immature platelets and cardiovascular events in patients with stable coronary artery disease	4
Bridging specialties: repurposing platelet drugs prescribed by cardiologists to help infectious disease doctors treat Staphylococcus aureus bacteremia	4
Finding and following: a deep learning-based pipeline for tracking platelets during thrombus formation in vivo and ex vivo	4
Molecular insights on Eltrombopag: potential mitogen stimulants, angiogenesis, and therapeutic radioprotectant through TPO-R activation	4
Eltrombopag modulates the phenotypic evolution and potential immunomodulatory roles of monocytes/macrophages in immune thrombocytopenia	4
Glycan-Lectin interactions between platelets and tumor cells drive hematogenous metastasis	4
The phenotype of cryopreserved platelets influences the formation of platelet-leukocyte aggregates in an in vitro model	4
Thrombus remodelling by reversible and irreversible P2Y ₁₂ inhibitors	4
Real-life clinical practice in Spain in the setting of new drug availability for ITP treatment. A Delphi-based Spanish expert panel consensus	4