OOIR: Observatory of International Research

Papers

(The TQCC of Platelets is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)

Article	Citations
Contributing role of mitochondrial energy metabolism on platelet adhesion, activation and thrombus formation under blood flow conditions	55
High rate of extreme thrombocytosis indicates bone marrow hyperactivity and splenic dysfunction among congenital diaphragmatic hernia patients	46
Prostacyclin analogues decrease platelet aggregation but have no effect on thrombin generation, fibrin clot structure, and fibrinolysis in pulmonary arterial hypertension: PAPAYA coagulation	35
Predictive performance of different bleeding risk scores in patients with atrial fibrillation and acute coronary syndrome or undergoing percutaneous coronary intervention	33
Platelet-derived microparticles stimulated by anti-β ₂ GPI/β ₂ GPI complexes induce pyroptosis of endothelial cells in antiphospho	29
Enhanced platelet sensitization is accompanied by increased expression of the transporter MRP4 and elevated plasma S1P levels in mild COVID-19 convalescents	26
Trends among platelet function, arterial calcium, and vascular function measures	26
How can we use proteomics to learn more about platelets?	25
Comparison of predictive value of risk scores for gastrointestinal bleeding in antiplatelet therapy	23
Development of an automated chemiluminescence enzyme immunoassay for the measurement of soluble C-type lectin-like receptor 2 (sCLEC-2) and molecular forms of sCLEC-2 measured in patient plasma	22
Apoptosis is one cause of thrombocytopenia in patients with high-altitude polycythemia	22
Sex-specific relationship between blood selenium levels and platelet count in a large cohort representative of the United States population	21
The role of miRNAs in regulation of platelet activity and related diseases - a bioinformatic analysis	21
Clinical features and treatment effect of HIV-associated immune thrombocytopenia—single center Ten-Years data summary	19
Crushed/chewed administration of potent P2Y₁₂ inhibitors in ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention: Systematic review and meta-anal	18
Chronic immune thrombocytopenia in a child with X-linked agammaglobulinemia-an uncommon phenotype	18
Platelets and open access – a new era dawns	17
Dual antiplatelet therapy is associated with high α-tubulin acetylation in circulating platelets from coronary artery disease patients	17
Bioinspired artificial platelets: past, present and future	16
The natural anticoagulant protein S; hemostatic functions and deficiency	16
Increased circulating platelet-derived extracellular vesicles in severe COVID-19 disease	16
Association between megakaryocyte abnormalities on bone marrow smear and response to thrombopoietin receptor agonists in adult patients with primary immune thrombocytopenia	15
Pre-operative platelet reactivity is a strong, independent predictor of bleeding complications after branched endovascular thoracoabdominal aortic aneurysm repair	15
Significance of mild thrombocytopenia in maintenance hemodialysis patients; a retrospective cohort study	15
Extracellular thiol isomerase ERp5 regulates integrin αIIbβ3 activation by inhibition of fibrinogen binding	15

Pro106Leu MPL mutation is associated with thrombocytosis and a low risk of thrombosis, splenomegaly and marrow fibrosis	15
Recombinant human thrombopoietin (rhTPO) of different dosing regimens for refractory/relapsed primary immune thrombocytopenia: a multicenter, randomized controlled trial and pharmacokinetics study	15
Effects of exercise on platelet reactivity after myocardial infarction: a randomized clinical trial	15
Janus kinase inhibitors ruxolitinib and baricitinib impair glycoprotein-VI mediated platelet function	14
Platelet response to aspirin in UK and Irish pregnancy cohorts: a genome-wide approach	13
European Delphi panel to build consensus on tapering and discontinuing thrombopoietin receptor agonists in immune thrombocytopenia	13
Phosphorylation of (Ser 291) in the linker insert of Syk negatively regulates ITAM signaling in platelets	13
Thrombosis in Covid-19 and non-Covid-19 pneumonia: role of platelets	13
Avatrombopag improves thrombocytopenia in MYH9-related disorder following eltrombopag treatment failure	12
Potential mechanisms involved on how systemic IgG antibodies specific to vascular endothelial growth factor (VEGF) and induced by active immunotherapy decrease platelet derived free-VEGF	12
Pathogen inactivation of platelets for transfusion	12
Tirofiban potentiates agonist-induced platelet activation and degranulation, despite effectively inhibiting aggregation	11
Variation in activation marker expression within the platelet population – a new parameter for evaluation of platelet flow cytometry data	11
Potential and limitations of PKA/ PKG inhibitors for platelet studies	11
Apolipoprotein A-I, elevated in trauma patients, inhibits platelet activation and decreases clot strength	11
Ion channels and ion homeostasis in the platelet and megakaryocyte	11
Association of thromboxane generation with the bleeding events in aspirin users	10
Circulating microRNAs as biomarkers and mediators of platelet activation	10
Inflammation modifies the platelet reactivity among thrombocytopenia patients undergoing percutaneous coronary intervention	10
Recent advances in microfluidic technology of arterial thrombosis investigations	10
Evolution of platelet activation parameters during septic shock in intensive care unit	10
In memory of Dr. Susan S. Smyth, MD/Ph.D.	10
Developmental differences of in vitro cultured murine bone marrow- and fetal liver-derived megakaryocytes	10
Impact of thrombocytopenia-associated c.-118C>T and c.-140C>G ANKRD26 5’UTR variants in three-generational pedigree	10
miR-28-5p targeted Rap1b attenuates splenic inflammation infiltration in immune thrombocytopenia	9
Neurosurgical bleeding in platelet storage pool disorder: a case report	9
Frozen and cold-stored platelets: reconsidered platelet products	9
Role of platelet count in a murine stasis model of deep vein thrombosis	9
A splice mutation in RASGRP2 gene in the patient with recurrent epistaxis and nasal vascular malformation	9
Deep learning, 3D ultrastructural analysis reveals quantitative differences in platelet and organelle packing in COVID-19/SARSCoV2 patient-derived platelets	9
Thrombosis and hemorrhage in myeloproliferative neoplasms: The platelet perspective	9
Cardiometabolic risk factor burden associates with an immature platelet profile	9
Higher body mass index raises immature platelet count: potential contribution to obesity-related thrombosis	9
EloA promotes HEL polyploidization upon PMA stimulation through enhanced ERK1/2 activity	8
Efficacy and safety of two rituximab biosimilars for treating immune thrombocytopenia: a reference-product matched study	8
Early recognition of sepsis-induced coagulopathy using the C2PAC index: a ratio of soluble type C lectin-like receptor 2 (sCLEC-2) level and platelet count	8
Anti-PF4/polyanion antibodies in COVID-19 patients are associated with disease severity and pulmonary pathology	8
Application of the Cellular Thermal Shift Assay (CETSA) to validate drug target engagement in platelets	8
Platelet-derived respiratory-competent mitochondria transfer to mesenchymal stem cells to promote wound healing via metabolic reprogramming	8
Congenital thrombocytopenia associated with a heterozygous variant in the MEIS1 gene encoding a transcription factor essential for megakaryopoiesis	8
The safety and efficacy of indobufen or aspirin combined with clopidogrel in patients with acute myocardial infarction after percutaneous coronary intervention	8
Factors influencing platelet isolation: a prospective multicenter study from Western China	8
In vitro evaluation of platelet extracellular vesicles (PEVs) for corneal endothelial regeneration	8
Evaluation of human platelet granules by structured illumination laser fluorescence microscopy	8
What can we learn from senescent platelets, their transcriptomes and proteomes?	8
The plant hormone abscisic acid stimulates megakaryocyte differentiation from human iPSCs in vitro	8
Additional efficacy analysis of avatrombopag phase III data for the treatment of adults with immune thrombocytopenia	7
Thrombocytopathy vs Platelet hyper-reactivity in COVID-19: diverse pathologies, disease outcomes and therapeutic implications	7
Effect of avatrombopag in the management of severe and refractory chemotherapy-induced thrombocytopenia (CIT) in patients with solid tumors	7
Cryopreservation affects platelet macromolecular composition over time after thawing and differently impacts on cancer cells behavior in vitro	7

Q94 is not a selective modulator of proteinase-activated receptor 1 (PAR1) in platelets	7
Multiple myeloma and its treatment contribute to increased platelet reactivity	7
Platelet counts in HFE p.C282Y/p.C282Y and wt/wt post-screening clinical evaluation participants	7
Platelet index on admission as a predictor of bacteremia in acute cholangitis: a 7-year retrospective observational study	7
Age and outcomes following personalized antiplatelet therapy in chronic coronary syndrome patients: a post hoc analysis of the randomized PATH-PCI trial	7
Evaluating stored platelet shape change using imaging flow cytometry	7
Roles of non-coding RNA in megakaryocytopoiesis and thrombopoiesis: new target therapies in ITP	7
Alantolactone induces platelet apoptosis by activating the Akt pathway	7