OOIR: Observatory of International Research

Papers

(The TQCC of Platelets is 6. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Platelets editorial 2022: transitioning	51
Proteomics-wise, how similar are mouse and human platelets?	37
Nebulization with alkaline hipertonic ibuprofen induces a rapid increase in platelets circulating in COVID-19 patients but not in healthy subjects	32
Thrombosis and hemorrhage in myeloproliferative neoplasms: The platelet perspective	30
Frequency and molecular basis of CD36 deficiency among platelet donors in Kunming, China	25
Cardiometabolic risk factor burden associates with an immature platelet profile	23
Effect of aspirin dosage on oxidative stress and platelet reactivity in patients undergoing coronary artery bypass grafting (APRICOT): randomized controlled trial	21
Evaluation of human platelet granules by structured illumination laser fluorescence microscopy	20
Platelet–leukocyte interactions in the pathogenesis of viral infections	20
Predictive performance of different bleeding risk scores in patients with atrial fibrillation and acute coronary syndrome or undergoing percutaneous coronary intervention	20
Effects of electret coating technology on coronary stent thrombogenicity	19
The complementary roles of VAMP-2, -3, and -7 in platelet secretion and function	18
How can we use proteomics to learn more about platelets?	18
Early recognition of sepsis-induced coagulopathy using the C2PAC index: a ratio of soluble type C lectin-like receptor 2 (sCLEC-2) level and platelet count	17
Factors influencing platelet isolation: a prospective multicenter study from Western China	17
The phenotype of cryopreserved platelets influences the formation of platelet-leukocyte aggregates in an in vitro model	17
Enhanced platelet sensitization is accompanied by increased expression of the transporter MRP4 and elevated plasma S1P levels in mild COVID-19 convalescents	17
What can the plasma proteome tell us about platelets (and vice versa)?	17
Regulation of lipid metabolism: a new strategy for platelet storage	17
Comparison of predictive value of risk scores for gastrointestinal bleeding in antiplatelet therapy	17
Molecular insights on Eltrombopag: potential mitogen stimulants, angiogenesis, and therapeutic radioprotectant through TPO-R activation	16
Effects of different doses of tirofiban combined with dual antiplatelet drugs on platelet indices, vascular endothelial function, and major adverse cardiovascular events in patients with acute ST-segm	16
First-in-human study to assess the safety, pharmacokinetics, and pharmacodynamics of BMS-986141, a novel, reversible, small-molecule, PAR4 agonist in non-Japanese and Japanese healthy participants	15
Development of an automated chemiluminescence enzyme immunoassay for the measurement of soluble C-type lectin-like receptor 2 (sCLEC-2) and molecular forms of sCLEC-2 measured in patient plasma	15
Real-life clinical practice in Spain in the setting of new drug availability for ITP treatment. A Delphi-based Spanish expert panel consensus	15

Application of the Cellular Thermal Shift Assay (CETSA) to validate drug target engagement in platelets	14
Activation of AMPK in platelets promotes the production of offspring	14
Finding and following: a deep learning-based pipeline for tracking platelets during thrombus formation in vivo and ex vivo	14
New αIIbβ3 variants in 28 Turkish Glanzmann patients; structural hypothesis for complex activation by residues variations in I-EGF domains	14
Platelet-derived mitochondria transfer facilitates wound-closure by modulating ROS levels in dermal fibroblasts	13
What can we learn from senescent platelets, their transcriptomes and proteomes?	13
The utility of flow cytometric platelet forward scatter as an alternative to mean platelet volume	13
The potential utilization of platelet-derived extracellular vesicles in clinical treatment	13
Thrombus remodelling by reversible and irreversible P2Y ₁₂ inhibitors	12
Immunological platelet transfusion refractoriness: current insights from mechanisms to therapeutics	12
The plant hormone abscisic acid stimulates megakaryocyte differentiation from human iPSCs in vitro	12
GALE variants associated with syndromic manifestations, macrothrombocytopenia, bleeding, and platelet dysfunction	11
Enrichment of plasma in platelets and extracellular vesicles by the counterflow to erythrocyte settling	11
A platelet lipidomics signature in patients with COVID-19	11
Contributing role of mitochondrial energy metabolism on platelet adhesion, activation and thrombus formation under blood flow conditions	11
EDTA stabilizes the concentration of platelet-derived extracellular vesicles during blood collection and handling	10
High rate of extreme thrombocytosis indicates bone marrow hyperactivity and splenic dysfunction among congenital diaphragmatic hernia patients	10
Evidence for a PI3-kinase independent pathway in the regulation of Rap1b activation downstream of the P2Y12 receptor in platelets	9
Immature platelets and cardiovascular events in patients with stable coronary artery disease	9
Prostacyclin analogues decrease platelet aggregation but have no effect on thrombin generation, fibrin clot structure, and fibrinolysis in pulmonary arterial hypertension: PAPAYA coagulation	9
Akt pathway activation reduces platelet apoptosis and contributes to the increase of platelet counts in solid tumor patients	9
Trends among platelet function, arterial calcium, and vascular function measures	9
EloA promotes HEL polyploidization upon PMA stimulation through enhanced ERK1/2 activity	9
Apoptosis is one cause of thrombocytopenia in patients with high-altitude polycythemia	9
Stability and utility of flow cytometric platelet activation tests: A modality to bridge the gap between diagnostic demand and supply	8
Platelets enhance CD4+ central memory T cell responses via platelet factor 4-dependent mitochondrial biogenesis and cell proliferation	8
Thrombocytopenia and platelet count recovery in patients with sepsis-3: a retrospective observational study	8
Injectable platelet-rich fibrin positively regulates osteogenic differentiation of stem cells from implant hole via the ERK1/2 pathway	8
Platelet-derived microparticles stimulated by anti-β ₂ GPI/β ₂ GPI complexes induce pyroptosis of endothelial cells in antiphospho	8
Anti-PF4/polyanion antibodies in COVID-19 patients are associated with disease severity and pulmonary pathology	8
Efficacy of platelet transfusion in cardiac surgery	8
Frozen and cold-stored platelets: reconsidered platelet products	8
Comparison of the effects of platelet concentrates produced by high and low-speed centrifugation protocols on the healing of critical-size defects in rat calvaria: a microtomographic and histomorphome	8
The role of miRNAs in regulation of platelet activity and related diseases - a bioinformatic analysis	8
Effect of iron supplementation on platelet count in adult patients with iron deficiency anemia	8
Neonatal platelet physiology and implications for transfusion	8
Developing human tissue engineered arterial constructs to simulate human in vivo thrombus formation	8
The safety and efficacy of indobufen or aspirin combined with clopidogrel in patients with acute myocardial infarction after percutaneous coronary intervention	8
C-type lectin-like receptor-2 (CLEC-2) is a key regulator of kappa-carrageenan-induced tail thrombosis model in mice	7
Platelets and open access – a new era dawns	7
Successful mRNA SARS-Cov-2 vaccine rechallenge after a first episode of immune thrombocytopenic purpura	7
Vaccine-induced immune thrombotic thrombocytopenia in a male after Ad26.COV2.S vaccination presenting as cerebral venous sinus thrombosis	7
Anti-GPVI (HY101) activates platelets in a multicolor flow cytometry panel	7
Healthy pediatric platelets are moderately hyporeactive in comparison with adults’ platelets	7
Predictors of high platelet reactivity assessed by Multiple Electrode Aggregometry in healthy individuals ‒ the role of leukocyte count	7
Editorial: structure–function relationships of tyrosine kinase- and tyrosine phosphatase-linked receptors in platelets and megakaryocytes	7
Congenital thrombocytopenia associated with a heterozygous variant in the MEIS1 gene encoding a transcription factor essential for megakaryopoiesis	7
Efficacy and safety of two rituximab biosimilars for treating immune thrombocytopenia: a reference-product matched study	7
Sex-specific relationship between blood selenium levels and platelet count in a large cohort representative of the United States population	7
Tailoring antiplatelet therapy in older patients with coronary artery disease	7

Platelet-derived extracellular vesicles play an important role in platelet transfusion therapy	7
Treatment of immune thrombocytopenia with hetrombopag olamine tablets in a Kabuki syndrome patient with new KMT2D mutations	7
Scanning transmission X-ray microscopy study of subcellular granules in human platelets at the carbon K- and calcium L2,3-edges	7
The natural anticoagulant protein S; hemostatic functions and deficiency	6
Distinct phenotypes of platelet, monocyte, and neutrophil activation occur during the acute and convalescent phase of COVID-19	6
Human Platelets and Influenza Virus: Internalization and Platelet Activation	6
The utility of platelet activation biomarkers in thrombotic microangiopathies	6
Management of a twin pregnancy patient with Glanzmann thrombasthenia might be caused by a novel ITGA2B gene mutation (c.2822G>A): a case report and family investigati	6
Gravity sedimentation reveals functionally and morphologically different platelets in human blood	6
Branched endovascular aortic aneurysm repair decreases platelet reactivity and platelet-rich thrombus formation – a prospective, cohort study	6
Edi(torial) 2024: action plan for change and new initiatives	6
In vitro evaluation of platelet extracellular vesicles (PEVs) for corneal endothelial regeneration	6
Increased circulating platelet-derived extracellular vesicles in severe COVID-19 disease	6
A case-control study of bleeding risk in children with 22q11.2 deletion syndrome undergoing cardiac surgery	6
ALB–PRF facilitates chondrogenesis by promoting chondrocytes migration, proliferation and differentiation	6