OOIR: Observatory of International Research

Papers

(The TQCC of Platelets is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-05-01 to 2024-05-01.)

Article	Citations
Prediction of severe illness due to COVID-19 based on an analysis of initial Fibrinogen to Albumin Ratio and Platelet count	111
Immunothrombosis and thromboinflammation in host defense and disease	88
Platelet functions and activities as potential hematologic parameters related to Coronavirus Disease 2019 (Covid-19)	64
Hemostatic laboratory derangements in COVID-19 with a focus on platelet count	61
A proof of evidence supporting abnormal immunothrombosis in severe COVID-19: naked megakaryocyte nuclei increase in the bone marrow and lungs of critically ill patients	51
Platelet Rich Plasma in Orthopedic Surgical Medicine.	44
Technical and biological review of authorized medical devices for platelets-rich plasma preparation in the field of regenerative medicine	37
PRP in wound healing applications	36
Platelet calcium signaling by G-protein coupled and ITAM-linked receptors regulating anoctamin-6 and procoagulant activity	34
Platelet rich plasma in oral and maxillofacial surgery from the perspective of composition	34
A rationale for blocking thromboinflammation in COVID-19 with Btk inhibitors	33
Novel antiplatelet strategies targeting GPVI, CLEC-2 and tyrosine kinases	32
In vivo evaluation of the biocompatibility and biodegradation of a new denatured plasma membrane combined with liquid PRF (Alb-PRF)	30
Search for SARS-CoV-2 RNA in platelets from COVID-19 patients	30
The thrombopoietin receptor: revisiting the master regulator of platelet production	30
Role of platelets and megakaryocytes in adaptive immunity	29
Cerebral venous sinus thrombosis associated with spontaneous heparin-induced thrombocytopenia syndrome after total knee arthroplasty	29
Over time relationship between platelet reactivity, myocardial injury and mortality in patients with SARS-CoV-2-associated respiratory failure	26
Rotational thromboelastometry (ROTEM) profiling of COVID–19 patients	25
Neonatal platelet physiology and implications for transfusion	24
Platelet-rich plasma promotes bone formation, restrains adipogenesis and accelerates vascularization to relieve steroids-induced osteonecrosis of the femoral head	23
Platelet removal by single-step centrifugation	21
Risk of major adverse cardiovascular events of CYP2C19 loss-of-function genotype guided prasugrel/ticagrelor vs clopidogrel therapy for acute coronary syndrome patients undergoing percutaneous	21
Platelets and viruses	21
Efficacy and safety evaluation of avatrombopag in immune thrombocytopenia: analyses of a phase III study and long-term extension	21

The structure of CLEC-2: mechanisms of dimerization and higher-order clustering	20
Isolation of murine bone marrow by centrifugation or flushing for the analysis of hematopoietic cells – a comparative study	20
Recent advances in understanding spleen tyrosine kinase (SYK) in human biology and disease, with a focus on fostamatinib	19
Application of Platelet Rich Fibrin in Tissue Engineering: Focus on Bone Regeneration	19
Early recognition of sepsis-induced coagulopathy using the C2PAC index: a ratio of soluble type C lectin-like receptor 2 (sCLEC-2) level and platelet count	18
Novel antiplatelet targets in the treatment of acute coronary syndromes	17
Platelet–leukocyte interactions in the pathogenesis of viral infections	17
Human platelet lysates for human cell propagation	17
Extensive characterization of the composition and functional activities of five preparations of human platelet lysates for dedicated clinical uses	17
MicroRNA-126 is a regulator of platelet-supported thrombin generation	17
Platelets and renal failure in the SARS-CoV-2 syndrome	17
Transient appearance of EDTA dependent pseudothrombocytopenia in a patient with 2019 novel coronavirus pneumonia	16
Immobilized collagen prevents shedding and induces sustained GPVI clustering and signaling in platelets	16
Use of electron microscopy to study platelets and thrombi	16
Bioinspired artificial platelets: past, present and future	15
Structure-function relationship of the platelet glycoprotein VI (GPVI) receptor: does it matter if it is a dimer or monomer?	15
The efficacy and safety of thrombopoietin receptor agonists in patients with chronic liver disease undergoing elective procedures: a systematic review and meta-analysis	14
The role of miRNAs in regulation of platelet activity and related diseases - a bioinformatic analysis	14
Cytosolic and mitochondrial Ca²⁺ signaling in procoagulant platelets	13
Alterations in platelets during SARS-CoV-2 infection	13
Release of α-granule contents during platelet activation	13
Efficacy and safety of eltrombopag in Chinese patients with chronic immune thrombocytopenia: stage 2 results from a multicenter phase III study	12
Thrombosis in Covid-19 and non-Covid-19 pneumonia: role of platelets	12
EDTA stabilizes the concentration of platelet-derived extracellular vesicles during blood collection and handling	12
Platelet reticulated forms, size indexes and functional activity. Interactions in healthy volunteers.	12
Targeting platelet inhibition receptors for novel therapies: PECAM-1 and G6b-B	12
Frozen and cold-stored platelets: reconsidered platelet products	12
Diagnostic and prognostic role of platelets in patients with sepsis and septic shock	12
Severe thrombocytopenia in adults undergoing extracorporeal membrane oxygenation is predictive of thrombosis	12
Zinc: an endogenous and exogenous regulator of platelet function during hemostasis and thrombosis	12
Platelet count and function in umbilical cord blood versus peripheral blood in term neonates	12
Platelets in dengue infection: more than a numbers game	11
Platelet activation by charged ligands and nanoparticles: platelet glycoprotein receptors as pattern recognition receptors	11
In vitro evaluation of platelet extracellular vesicles (PEVs) for corneal endothelial regeneration	11
Platelet-derived microparticles stimulated by anti-β ₂ GPI/β ₂ GPI complexes induce pyroptosis of endothelial cells in antiphospho	11
Antiplatelet drugs and liver fibrosis	11
Platelet-rich plasma loaded with antibiotics as an affiliated treatment for infected bone defect by combining wound healing property and antibacterial activity	11
ABCG5 and ABCG8 gene variations associated with sitosterolemia and platelet dysfunction	11
Harmonizing light transmission aggregometry in the Netherlands by implementation of the SSC-ISTH guideline	11
Overcoming challenges in developing small molecule inhibitors for GPVI and CLEC-2	11
Janus kinase inhibitors ruxolitinib and baricitinib impair glycoprotein-VI mediated platelet function	11
Left ventricular assist device implantation causes platelet dysfunction and proinflammatory platelet-neutrophil interaction	11
Differential effect of clopidogrel and ticagrelor on leukocyte count in relation to patient characteristics, biomarkers and genotype: a PLATO substudy	10
Thrombocytopenia and platelet count recovery in patients with sepsis-3: a retrospective observational study	10
The efficacy and safety of CYP2C19 genotype-guided antiplatelet therapy compared with conventional antiplatelet therapy in patients with acute coronary syndrome or undergoing percutaneous coronary int	10
In vitro-derived platelets: the challenges we will have to face to assess quality and safety	10
Injectable platelet-rich fibrin positively regulates osteogenic differentiation of stem cells from implant hole via the ERK1/2 pathway	10
High-efficiency unassisted transfection of platelets with naked double-stranded miRNAs modulates signal-activated translation and platelet function	9
A proprietary GMP human platelet lysate for the expansion of dermal fibroblasts for clinical applications	9
The enigmatic nature of the triggering receptor expressed in myeloid cells -1 (TLT- 1)	9

P2X1: a unique platelet receptor with a key role in thromboinflammation	9
Higher body mass index raises immature platelet count: potential contribution to obesity-related thrombosis	9
New oral protease-activated receptor 4 antagonist BMS-986120: tolerability, pharmacokinetics, pharmacodynamics, and gene variant effects in humans	9
Mechanisms of platelet release: in vivo studies and in vitro modeling	9
Selective inhibition of thromboinflammation in COVID-19 by Btk inhibitors	9
High extracellular phosphate increases platelet polyphosphate content	9
Platelet Function Assays for the Diagnosis of Aspirin Resistance	9
Sex differences in antiplatelet therapy: state-of-the art	9
Immature platelet indices alongside procalcitonin for sensitive and specific identification of bacteremia in the intensive care unit	9
Distinct phenotypes of platelet, monocyte, and neutrophil activation occur during the acute and convalescent phase of COVID-19	9
Apoptosis is one cause of thrombocytopenia in patients with high-altitude polycythemia	9
Anti-PF4/polyanion antibodies in COVID-19 patients are associated with disease severity and pulmonary pathology	8
Factor Xa and thrombin induce endothelial progenitor cell activation. The effect of direct oral anticoagulants	8
Evolution of platelet activation parameters during septic shock in intensive care unit	8
Prevalence and natural history of variants in the ANKRD26 gene: a short review and update of reported cases	8
Effect of differently coated silver nanoparticles on hemostasis	8
GPIb-IX-V and platelet clearance	8
Platelet-derived respiratory-competent mitochondria transfer to mesenchymal stem cells to promote wound healing via metabolic reprogramming	8
Structural analysis of resting mouse platelets by 3D-EM reveals an unexpected variation in α-granule shape	8
Whole blood flow cytometry protocol for the assessment of platelet phenotype, function, and cellular interactions	8
Investigation of fibrinogen in early bleeding of patients with newly diagnosed acute promyelocytic leukemia	8
The potency of selatogrel, a reversible antagonist of the P2Y12 receptor, is affected by calcium concentration	7
Pathogen inactivation of platelets for transfusion	7
Characteristics of L-PRP preparations for treating Achilles tendon rupture within the PATH-2 study	7
Platelets: bridging thrombosis and inflammation	7
Statins potentiate the antibacterial effect of platelets on Staphylococcus aureus	7
Refractory immune thrombocytopenia successfully treated with bortezomib in a child with 22q11.2 deletion syndrome, complicated by Evans syndrome and hypogammaglobulinemia	7
Prognostic significance of thrombocytosis in lung cancer: a systematic review and meta-analysis	7
Recovery of platelet reactivity following cessation of either aspirin or ticagrelor in patients treated with dual antiplatelet therapy following percutaneous coronary intervention: a GLOBAL LEADERS su	7
Helicobacter pylori protein that binds to and activates platelet specifically reacts with sera of H. pylori-associated chronic immune thrombocytopenia	7
Optimized tool for evaluation of platelet function measured by impedance aggregometry	7
Platelets enhance CD4+ central memory T cell responses via platelet factor 4-dependent mitochondrial biogenesis and cell proliferation	7
Association of lipoprotein(a) with platelet aggregation and thrombogenicity in patients undergoing percutaneous coronary intervention	7
New presentations and exacerbations of immune thrombocytopenia after coronavirus disease 2019 vaccinations: the Taiwan experience	7
Distribution and quantification of activated platelets in platelet-rich fibrin matrices	7
Management of immune thrombotic thrombocytopenic purpura with caplacizumab: a Canadian, single-centre, real-world experience	7
Platelet-derived mitochondria transfer facilitates wound-closure by modulating ROS levels in dermal fibroblasts	7
Enrichment of plasma in platelets and extracellular vesicles by the counterflow to erythrocyte settling	7
Signaling mechanisms of the platelet glycoprotein Ib-IX complex	7