Journal of Internal Medicine

Article	Citations
COVID‐19 diagnosis and management: a comprehensive review	834
Clinical and epidemiological characteristics of 1420 European patients with mild‐to‐moderate coronavirus disease 2019	559
Senolytic drugs: from discovery to translation	527
Older age and comorbidity are independent mortality predictors in a large cohort of 1305 COVID‐19 patients in Michigan, United States	249
The Mediterranean diet and health: a comprehensive overview	233
Perspective: Vitamin D deficiency and COVID‐19 severity – plausibly linked by latitude, ethnicity, impacts on cytokines, ACE2 and thrombosis	164
Prevalence and 6‐month recovery of olfactory dysfunction: a multicentre study of 1363 COVID‐19 patients	157
Systemic amyloidosis from A (AA) to T (ATTR): a review	144
Ambient air pollution and cardiovascular diseases: An umbrella review of systematic reviews and meta‐analyses	141
Cytokine storm syndrome in coronavirus disease 2019: A narrative review	136
Short‐term neuropsychiatric outcomes and quality of life in COVID‐19 survivors	134
The impact of novel coronavirus COVID‐19 on noncommunicable disease patients and health systems: a review	119
COVID‐19 retinal microangiopathy as an in vivo biomarker of systemic vascular disease?	113
Homocysteine – from disease biomarker to disease prevention	109
Immunity to SARS‐CoV‐2 induced by infection or vaccination	96
Breathing, speaking, coughing or sneezing: What drives transmission of SARS‐CoV‐2?	94
Nanotechnology for modern medicine: next step towards clinical translation	89
Insights into disparities observed with COVID‐19	87
Advances in the Omicron variant development	86
Practical recommendations for timely, accurate diagnosis of symptomatic Alzheimer’s disease (MCI and dementia) in primary care: a review and synthesis	80
Direct oral anticoagulant use and risk of severe COVID‐19	72
Elevated markers of gut leakage and inflammasome activation in COVID‐19 patients with cardiac involvement	71
Current treatment of non‐alcoholic fatty liver disease	68
How can dementia and disability be prevented in older adults: where are we today and where are we going?	68
Patients with Lemierre syndrome have a high risk of new thromboembolic complications, clinical sequelae and death: an analysis of 712 cases	61

Cancer survival statistics for patients and healthcare professionals – a tutorial of real‐world data analysis	61
Racial disparities in COVID‐19 deaths reveal harsh truths about structural inequality in America	60
Association of mitochondrial DNA copy number with metabolic syndrome and type 2 diabetes in 14 176 individuals	60
Arterial stiffness in acute COVID‐19 and potential associations with clinical outcome	56
High frequency of antiphospholipid antibodies in critically ill COVID‐19 patients: a link with hypercoagulability?	54
Epigenetic regulation of insulin action and secretion – role in the pathogenesis of type 2 diabetes	54
Transitioning from cerebrospinal fluid to blood tests to facilitate diagnosis and disease monitoring in Alzheimer's disease	53
Genetics of coronary artery disease in the post‐GWAS era	48
Lessons from 20 years with COX‐2 inhibitors: Importance of dose–response considerations and fair play in comparative trials	47
Inflammatory and fibrotic mechanisms in NAFLD—Implications for new treatment strategies	46
Adherence to a healthy sleep pattern is associated with lower risks of all‐cause, cardiovascular and cancer‐specific mortality	46
Treatment with proton pump inhibitors increases the risk of secondary infections and ARDS in hospitalized patients with COVID‐19: coincidence or underestimated risk factor?	45
Hypocretins (orexins): The ultimate translational neuropeptides	45
Diagnosis and management of diabetes insipidus for the internist: an update	44
Robust humoral and cellular immune responses and low risk for reinfection at least 8 months following asymptomatic to mild COVID‐19	44
Current and emerging disease‐modulatory therapies and treatment targets for multiple sclerosis	44
Long‐term neuropsychiatric outcomes in COVID‐19 survivors: A 1‐year longitudinal study	44
Assessment of thirty‐day readmission rate, timing, causes and predictors after hospitalization with COVID‐19	43
Tocilizumab shortens time on mechanical ventilation and length of hospital stay in patients with severe COVID‐19: a retrospective cohort study	43
Alveolar progenitor cells and the origin of lung cancer	42
Ethnic differences in adiposity and diabetes risk – insights from genetic studies	41
BCG scarring and improved child survival: a combined analysis of studies of BCG scarring	41
Hypoalbuminemia in COVID‐19: assessing the hypothesis for underlying pulmonary capillary leakage	41
The link between vitamin D and COVID‐19: distinguishing facts from fiction	40
Half‐year follow‐up of patients recovering from severe COVID‐19: Analysis of symptoms and their risk factors	40
Respiratory dysfunction three months after severe COVID‐19 is associated with gut microbiota alterations	39
Type 2 diabetes and remission: practical management guided by pathophysiology	39
Current concepts regarding Graves’ orbitopathy	39
Gastrointestinal bleeding in hospitalized COVID‐19 patients: a propensity score matched cohort study	39
Deep brain stimulation for Parkinson's disease	38
Is obesity a manifestation of systemic racism? A ten‐point strategy for study and intervention	37
Outcomes of COVID‐19‐positive acute coronary syndrome patients: A multisource electronic healthcare records study from England	37
Transthyretin amyloid deposits in lumbar spinal stenosis and assessment of signs of systemic amyloidosis	36
Pediatric obesity—Long‐term consequences and effect of weight loss	36
Acute odynophagia: A new symptom of COVID‐19 during the SARS‐CoV‐2 Omicron variant wave in Sweden	35
Oral anticoagulants for nonvalvular atrial fibrillation in frail elderly patients: insights from the ARISTOPHANES study	35
The role of environmental exposures and gene–environment interactions in the etiology of systemic lupus erythematous	35
Mitochondrial diseases in adults	34
The Stockholm CREAtinine Measurements (SCREAM) project: Fostering improvements in chronic kidney disease care	34
Cyclosporine A plus low‐dose steroid treatment in COVID‐19 improves clinical outcomes in patients with moderate to severe disease: A pilot study	33
Increased vulnerability to COVID‐19 in chronic kidney disease	33
Review of cadmium exposure and smoking‐independent effects on atherosclerotic cardiovascular disease in the general population	33
Evidence that a deviation in the kynurenine pathway aggravates atherosclerotic disease in humans	33
Remnant cholesterol predicts progression of diabetic nephropathy and retinopathy in type 1 diabetes	33
COVID‐19 and renin‐angiotensin system inhibition: role of angiotensin converting enzyme 2 (ACE2) ‐ Is there any scientific evidence for controversy?	33
Humoral response to two doses of BNT162b2 vaccination in people with HIV	32
Coronary artery calcium scoring: an evidence‐based guide for primary care physicians	31
Associations between nutritional frailty and 8‐year all‐cause mortality in older adults: The Salus in Apulia Study	31
The circadian syndrome predicts cardiovascular disease better than metabolic syndrome in Chinese adults	31
Inflammatory bowel disease and psoriasis: modernizing the multidisciplinary approach	31

Food allergy and hypersensitivity reactions in children and adults—A review	31
Seropositivity in blood donors and pregnant women during the first year of SARS‐CoV‐2 transmission in Stockholm, Sweden	31
Aspects of colorectal cancer screening, methods, age and gender	31
Cardiovascular risk factors and lifestyle behaviours in relation to longevity: a Mendelian randomization study	31
Male reproductive health and intergenerational metabolic responses from a small RNA perspective	30
Prevalence and 24‐month recovery of olfactory dysfunction in COVID‐19 patients: A multicentre prospective study	30
Abnormal thyroid function is common in takotsubo syndrome and depends on two distinct mechanisms: results of a multicentre observational study	30
Association of the metabolic syndrome with mortality and major adverse cardiac events: A large chronic kidney disease cohort	30
Induction of specific brain oscillations may restore neural circuits and be used for the treatment of Alzheimer's disease	30
The complexity of kidney disease and diagnosing it – cystatin C, selective glomerular hypofiltration syndromes and proteome regulation	29
Use of proton pump inhibitors and risk of adverse clinical outcomes from COVID‐19: a meta‐analysis	29
New tuberculosis vaccines: advances in clinical development and modelling	29
IL‐15 is a biomarker involved in the development of rapidly progressive interstitial lung disease complicated with polymyositis/dermatomyositis	29
COVID‐19 in Latin America and the Caribbean: Two years of the pandemic	29
Liver mitochondrial DNA damage and genetic variability of Cytochrome b – a key component of the respirasome – drive the severity of fatty liver disease	29
Gender‐affirming hormone therapy: An updated literature review with an eye on the future	29
Cause of death based on systematic post‐mortem studies in patients with positive SARS‐CoV‐2 tissue PCR during the COVID‐19 pandemic	28
An update on polymyalgia rheumatica	28
Dilated cardiomyopathy and chronic cardiac inflammation: Pathogenesis, diagnosis and therapy	28
Risk of primary liver cancer in acute hepatic porphyria patients: A matched cohort study of 1244 individuals	28
PCSK9 inhibitors for COVID‐19: an opportunity to enhance the antiviral action of interferon in patients with hypercholesterolaemia	27
Clinical predictors of donor antibody titre and correlation with recipient antibody response in a COVID‐19 convalescent plasma clinical trial	27
Developmental regulation of barrier‐ and non‐barrier blood vessels in the CNS	26
Gene therapy for ischaemic heart disease and heart failure	26
Muscle‐strengthening activities and risk of cardiovascular disease, type 2 diabetes, cancer and mortality: A review of prospective cohort studies	26
Epigenetic aging: Biological age prediction and informing a mechanistic theory of aging	26
Tumour biomarkers: association with heart failure outcomes	26
Immunogenicity of SARS‐CoV‐2 mRNA vaccine in solid organ transplant recipients	26
Obesity in African‐Americans: The role of physiology	25
Human white adipose tissue: A highly dynamic metabolic organ	25
One‐year persistent symptoms and functional impairment in SARS‐CoV‐2 positive and negative individuals	25
Vitamin D, respiratory infections, and chronic disease: Review of meta‐analyses and randomized clinical trials	25
PCSK9 is associated with mortality in patients with septic shock: data from the ALBIOS study	25
The influence of the blood–brain barrier in the treatment of brain tumours	25
The roles of free iron, heme, haemoglobin, and the scavenger proteins haemopexin and alpha‐1‐microglobulin in preeclampsia and fetal growth restriction	25
Micronutrient deficiencies in heart failure: Mitochondrial dysfunction as a common pathophysiological mechanism?	24
Antibiotics and mental health: The good, the bad and the ugly	24
Genetic and molecular architecture of familial hypercholesterolemia	24
Pathogenesis of type 2 diabetes risk in black Africans: a South African perspective	24
Is systemic inflammation a missing link between periodontitis and hypertension? Results from two large population‐based surveys	23
A systems biology approach to understand gut microbiota and host metabolism in morbid obesity: design of the BARIA Longitudinal Cohort Study	23
Postural orthostatic tachycardia syndrome is associated with significant employment and economic loss	23
Post COVID‐19 condition diagnosis: A population‐based cohort study of occurrence, associated factors, and healthcare use by severity of acute infection	23
Use of the IL‐6R antagonist tocilizumab in hospitalized COVID‐19 patients	23
Low‐dose computed tomography lung cancer screening: Clinical evidence and implementation research	23
Prevalence and severity of coronary artery disease linked to prognosis in psoriasis and psoriatic arthritis patients: a multi‐centre cohort study	23
Sarcoidosis: Epidemiology and clinical insights	22
Hypertension genetics past, present and future applications	22
Methylprednisolone added to tocilizumab reduces mortality in SARS‐CoV‐2 pneumonia: An observational study	22
Systemic lupus erythematosus and cardiovascular disease	22
Changes in eicosapentaenoic acid and docosahexaenoic acid and risk of cardiovascular events and atrial fibrillation: A secondary analysis of the OMEMI trial	22
Where traditional Chinese medicine meets Western medicine in the prevention of rheumatoid arthritis	21
Ursodeoxycholic acid is associated with a reduction in SARS‐CoV‐2 infection and reduced severity of COVID‐19 in patients with cirrhosis	21
Global guidance for the recognition, diagnosis, and management of tumor‐induced osteomalacia	21
Lipoprotein(a) and SARS‐CoV‐2 infections: Susceptibility to infections, ischemic heart disease and thromboembolic events	21
Central nervous system zoning: How brain barriers establish subdivisions for CNS immune privilege and immune surveillance	21
Endovascular thrombectomy for acute ischemic stroke	21
Long‐term changes in adipose tissue gene expression following bariatric surgery	21
Distinct differences in gut microbial composition and functional potential from lean to morbidly obese subjects	21
So close, and yet so far away: The dichotomy of the specific immune response and inflammation in psoriasis and atopic dermatitis	20
Cardiovascular problems associated with IVF therapy	20
ACE inhibitors, angiotensin receptor blockers and endothelial injury in COVID‐19	20
The endocannabinoid system – current implications for drug development	20
Long‐term corticosteroid use, adrenal insufficiency and the need for steroid‐sparing treatment in adult severe asthma	20
Gut microbiome and amyotrophic lateral sclerosis: A systematic review of current evidence	20
Can we cure diabetic kidney disease? Present and future perspectives from a nephrologist's point of view	19
Reported muscle symptoms during statin treatment amongst Italian dyslipidaemic patients in the real‐life setting: the PROSISA Study	19
Critical COVID‐19 is associated with distinct leukocyte phenotypes and transcriptome patterns	19
Increased fracture risk after discontinuation of anti‐osteoporosis medications among hip fracture patients: A population‐based cohort study	19
There is no ‘African American Physiology’: the fallacy of racial essentialism	19
The potential of DNA methylation as a biomarker for obesity and smoking	19
Beating the odds with systematic individualized care: Nationwide prospective follow‐up of all patients with COVID‐19 in Iceland	19
Technological readiness and implementation of genomic‐driven precision medicine for complex diseases	18
Genetic characteristics predict response to venetoclax plus hypomethylating agents in relapsed or refractory acute myeloid leukemia	18
Viral infections and their relationship with catastrophic antiphospholipid syndrome: a possible pathogenic mechanism of severe COVID‐19 thrombotic complications	18
Cardiac foetal reprogramming: a tool to exploit novel treatment targets for the failing heart	18
Post‐Covid‐19‐vaccination adverse events and healthcare utilization among individuals with or without previous SARS‐CoV‐2 infection	18
Discrepancies between actual weight, weight perception and weight loss intention amongst persons with NAFLD	18
Promotion of vascular integrity in sepsis through modulation of bioactive adrenomedullin and dipeptidyl peptidase 3	17
BMI is positively associated with accelerated epigenetic aging in twin pairs discordant for body mass index	17

Statin exposure and the risk of dementia in individuals with hypercholesterolaemia	17
Low anti‐SARS‐CoV‐2 S antibody levels predict increased mortality and dissemination of viral components in the blood of critical COVID‐19 patients	17
Does exercise prevent major non‐communicable diseases and premature mortality? A critical review based on results from randomized controlled trials	17
Malmö POTS symptom score: Assessing symptom burden in postural orthostatic tachycardia syndrome	17
The pathogenesis of microthrombi in COVID‐19 cannot be controlled by DOAC: NETosis should be the target	16
Osteoarthritis, part of life or a curable disease? A bird's‐eye view	16
Genome‐wide search for genes affecting the age at diagnosis of type 1 diabetes	16
Incidence and survival of haemophagocytic lymphohistiocytosis: A population‐based cohort study from England	16
Big data in vascular surgery: registries, international collaboration and future directions	16
Clinical features of patients who had two COVID‐19 episodes: a European multicentre case series	16
Evaluation of SARS‐CoV‐2 antibody levels on hospital admission as a correlate of protection against mortality	16
Clinical characteristics and outcomes of immunosuppressed patients hospitalized with COVID‐19: experience from London	16
Vitamin D and COVID‐19—Revisited	16
Impact of the post‐COVID‐19 condition on health care after the first disease wave in Lombardy	16
Telehealth mitigates COPD disease progression compared to standard of care: a randomized controlled crossover trial	16
Homocysteine elevation in givosiran treatment: Suggested ALAS1 siRNA effect on cystathionine beta‐synthase	16
Shared decision‐making interventions: An overview and a meta‐analysis of their impact on vaccine uptake	16
A safe level of alcohol consumption: the right answer demands the right question	16
A follow‐up survey of patients with acquired angioedema due to C1‐inhibitor deficiency	16
Iron deficiency screening is a key issue in chronic inflammatory diseases: A call to action	16
Calcitonin gene‐related peptide (CGRP) is a key molecule released in acute migraine attacks—Successful translation of basic science to clinical practice	15
4D flow MRI hemodynamic biomarkers for cerebrovascular diseases	15
Respiratory and systemic monocytes, dendritic cells, and myeloid‐derived suppressor cells in COVID‐19: Implications for disease severity	15
Antibody‐dependent neutralizing capacity of the SARS‐CoV‐2 vaccine BNT162b2 with and without previous COVID‐19 priming	15
Low antispike antibody levels correlate with poor outcomes in COVID‐19 breakthrough hospitalizations	15
Twenty‐five years of biologicals in IBD: What´s all the hype about?	15
Aerobic exercise training and neurocognitive function in cognitively normal older adults: A one‐year randomized controlled trial	15
Growth hormone deficiency in adults with hypopituitarism—What are the risks and can they be eliminated by therapy?	14
Tuberculosis in patients with systemic lupus erythematosus–a 37‐year longitudinal survey‐based study	14
Primary aldosteronism: Higher volume load, cardiac output and arterial stiffness than in essential hypertension	14
Fat mass and fat‐free mass in relation to cardiometabolic diseases: a two‐sample Mendelian randomization study	14
Tenosynovial complications identify TTR cardiac amyloidosis among patients with hypertrophic cardiomyopathy phenotype	14
Reduction of protein‐bound uraemic toxins in plasma of chronic renal failure patients: A systematic review	14
Effectiveness of REGEN‐COV antibody cocktail against the B.1.617.2 (delta) variant of SARS‐CoV‐2: A cohort study	14
Treating hypothyroidism is not always easy: When to treat subclinical hypothyroidism, TSH goals in the elderly, and alternatives to levothyroxine monotherapy	14
Neuroimaging phenotypes of CSF1R‐related leukoencephalopathy: Systematic review, meta‐analysis, and imaging recommendations	14
Risk factors for anti‐drug antibody formation to infliximab: Secondary analyses of a randomised controlled trial	14
Nonalcoholic fatty liver disease is associated with a decreased myocardial mechano‐energetic efficiency	14
Cerebrotendinous xanthomatosis without neurological involvement	14