OOIR: Observatory of International Research

Papers

(The median citation count of Current Opinion in Lipidology is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)

Article	Citations
Genetic variation in apolipoprotein A-V in hypertriglyceridemia	54
Angiopoietin-like protein 8: a multifaceted protein instrumental in regulating triglyceride metabolism	52
Editorial introductions	52
Familial hypercholesterolemia-Plus: is the metabolic syndrome changing the clinical picture of familial hypercholesterolemia?	51
Alveolar macrophages: guardians of the alveolar lipid galaxy	40
Ups and downs in PCSK9 inhibition in the cardiovascular arena: a review	37
Triglyceride-rich lipoproteins, remnant-cholesterol, and atherosclerotic cardiovascular disease	34
ANGPTL4: a new mode in the regulation of intravascular lipolysis	34
Sphingomyelins and ceramides: possible biomarkers for dementia?	31
Universal screening for familial hypercholesterolaemia: how can we maximise benefits and minimise potential harm for children and their families?	30
Implementation science and genetic testing for familial hypercholesterolemia	29
The lipid-heart hypothesis from the Seven Countries Study of Cardiovascular Diseases	29
Lipid metabolism during pregnancy: consequences for mother and child	28
Familial hypercholesterolemia: The nexus of endothelial dysfunction and lipoprotein metabolism in COVID-19	28
Oxidized LDL receptors: a recent update	27
Familial hypercholesterolemia in children and the importance of early treatment	26
Lipoprotein(a) and peripheral artery disease: contemporary evidence and therapeutic advances	24
Editorial introductions	22
Exosomes and lipid metabolism in metabolic and cardiovascular disorders	22
Splice correction therapies for familial hypercholesterolemic patients with low-density lipoprotein receptor mutations	18
Nonalcoholic fatty liver disease: an update	18
Nutrition and its impact on cardiovascular disease	17
The current state of apolipoprotein E in dyslipidemia	17
Genetic determinants of pancreatitis risk in hypertriglyceridemia	16
A new SPRING in lipid metabolism	15

Familial hypercholesterolemia in pregnancy	15
Inhibition of angiopoietin-like 3 for the management of severe hypercholesterolemia	14
From clinical development to real-world outcomes with inclisiran	14
Lipid effects of glucagon-like peptide 1 receptor analogs	14
Inclisiran: present and future perspectives of a new effective LDL cholesterol-lowering agent	13
The intracellular chylomicron highway: novel insights into chylomicron biosynthesis, trafficking, and secretion	13
APOE and familial hypercholesterolemia	13
ANGPTL3 and ApoC-III inhibitors for treating hypertriglyceridemia in context: horses for courses?	13
The need for national and international registries of patients with elevated lipoprotein(a)	13
Are the lipid-lowering effects of incretin-based therapies relevant for cardiovascular benefit?	13
High-density lipoprotein functionality, cardiovascular health, and patterns of alcohol consumption: new insights and future perspectives	13
Can small dense LDL cholesterol be estimated from the lipid profile?	12
Newborn screening for lipid disorders	12
The emerging role of fat-inducing transcript 2 in endoplasmic reticulum proteostasis and lipoprotein biogenesis	11
Editorial introductions	11
The expanding role of lyso-phosphatidylcholine acyltransferase-3 (LPCAT3), a phospholipid remodeling enzyme, in health and disease	10
Genetic testing for familial hypercholesterolemia	10
Cardiomyocytes, sphingolipids and cardio myotoxicity	10
Preprint servers in lipidology: current status and future role	10
Pregnancy, cardiovascular health, and microchimerism	10
Recent dynamic studies of the metabolism of atherogenic lipoproteins: elucidating the mode of action of new therapies	10
Distinct roles of size-defined HDL subpopulations in cardiovascular disease	10
Clinical associations between exercise and lipoproteins	10
Altered cardiovascular risk pattern of LDL cholesterol in older adults	9
Circulating protein and lipid markers of early sepsis diagnosis and prognosis: a scoping review	9
Metabolic regulation of macrophage proliferation and function in atherosclerosis	9
Association of dietary patterns and components with atherosclerosis risk biomarkers in familial hypercholesterolemia	9
Prevention of cardiometabolic diseases through dietary modifications	8
LDL receptor-related protein 1 and its interacting partners in tissue homeostasis	8
Sphingosine-1-phosphate: metabolism, transport, atheroprotection and effect of statin treatment	8
Strategies for management of patients with elevated lipoprotein(a)	8
The feedback cycles between glucose, amino acids and lipids and alpha cell secretion and their role in metabolic fatty liver disease	7
Genotype–phenotype correlation in a large cohort of pediatric patients with heterozygous and homozygous familial hypercholesterolemia	7
Clonal hematopoiesis of indeterminate potential and the evolutionary lottery in chromosome 2: does that make human atherosclerosis special?	7
Editorial introductions	7
The pathophysiology of excess plasma-free cholesterol	7
Dietary fat, telomere length and cognitive function: unravelling the complex relations	6
Recent lipoprotein(a) trials	6
A contemporary snapshot of familial hypercholesterolemia registries	6
Assessment of cardiovascular disease risk: a 2023 update	6
Lipids and peripheral neuropathy	6
Navigating variants of uncertain significance in genetic dyslipidemia: how to assess and counsel patients	6
Lipidomics in gestational diabetes mellitus	6
Therapeutic application of genome editing in dyslipidemia	5
Atherogenic low-density lipoprotein and cardiovascular risk	5
Dietary factors and brain health	5
Translating guidelines into practice via implementation science: an update in lipidology	5
How should low-density lipoprotein cholesterol be calculated in 2022?	5
Editorial introduction	5
Diagnosis of remnant hyperlipidaemia	4

Regulation of cardiovascular calcification by lipids and lipoproteins	4
Bempedoic acid for nonalcoholic fatty liver disease: evidence and mechanisms of action	4
Understanding the ins and outs of lipoprotein (a) metabolism	4
Predictors of cardiovascular risk in familial hypercholesterolemia	4
Triglyceride-rich lipoprotein cholesterol and cardiovascular risk	4
Genetics of remnant cholesterol	4
Remnant cholesterol as a new lipid-lowering target to reduce cardiovascular events	4
Proprotein convertase subtilisin/kexin type 9-inhibition across different patient populations	4
Cholesterol 25-hydroxylase expression following immune activation in response to SARS-CoV-2 infection	4
Are Lipoprotein(a) levels decreased in insulin resistance and type 2 diabetes?	4
Resolution of apolipoprotein A1 and A2 proteoforms: their cardiometabolic correlates and implications for future research	4
Basic and translational evidence supporting the role of TM6SF2 in VLDL metabolism	3
Inflammation in atherosclerosis: a Big Idea that has underperformed so far	3
Complex actions of sodium glucose transporter-2 inhibitors on lipids, calcific atherosclerosis, and bone density	3
Bempedoic acid: new evidence and recommendations on use	3
Consensus and guidelines on lipoprotein(a) – seeing the forest through the trees	3
Established and potential cardiovascular risk factors in metabolic syndrome: Effect of bariatric surgery	3
Novel therapeutic opportunities for familial lecithin:cholesterol acyltransferase deficiency: promises and challenges	3
Circulating cell-free DNA and its association with cardiovascular disease: what we know and future perspectives	3
Editorial introduction	3
Orticumab: the potential to harness oxidized LDL to reduce coronary inflammation with plaque-targeted therapy	3
Fatty acid metabolism in cancer cells – the power of plasticity	3
Cholesteryl ester transfer protein inhibition: a pathway to reducing risk of morbidity and promoting longevity	3
Ketogenic therapies in mild cognitive impairment and dementia	2
Updates on genetics and molecular biology	2
Angiopoietin-like 3 inhibition and the liver: less is more?	2
Increasing fruits and vegetables to reduce mortality and promote independence	2
G protein-coupled receptor 146: new insights from genetics and model systems	2
Lipids and brain inflammation in APOE4-associated dementia	2
Dyslipidemia and aortic valve disease	2
Familial combined hyperlipidemia is a polygenic trait	2
Brain lipid metabolism: the emerging role of lipid droplets in glial cells	2
Links between ceramides and cardiac function	2
Editorial introductions	2
Angiopoietin-like protein 3 inhibitors and contemporary unmet needs in lipid management	2
PCSK9-directed therapies: an update	2
Editorial introduction	2
Proprotein convertase subtilisin/kexin type 9 inhibition after acute coronary syndrome or prior myocardial infarction	2
Proprotein convertase subtilisin/kexin type 9 as a drug target for abdominal aortic aneurysm	2
Editorial introduction	2
Polygenic contribution for familial hypercholesterolemia (FH)	2
Macrophage SR-B1 in atherosclerotic cardiovascular disease	2
Lipoprotein (a) in familial hypercholesterolaemia	2