Experimental Physiology

Article	Citations
	169
Nitrite supplementation alleviates cerebrovascular dysfunction in chronically stressed mice, but cognitive decline remains	78
Chasing genes at high‐altitude	64
Using environmental and exercise physiology to address gender inequalities in climate change and occupational health research	52
Erratum	52
Physiological assessment of a 16 day, 4385 km ultra‐endurance mountain bike race: A case study	45
Mechanosensory encoding in ex vivo muscle–nerve preparations	40
The physiology of survival: Fluid and food	36
Acute partial sleep restriction does not impact arterial function in young and healthy humans	34
Hyperpolarized [1‐13C]pyruvate combined with the hyperinsulinaemic euglycaemic and hypoglycaemic clamp technique in skeletal muscle in a large animal model	33
Chitinase 3‐like 1 overexpression aggravates hypoxia–reoxygenation injury in IEC‐6 cells by inhibiting the PI3K/AKT signalling pathway	32
Investigating the control of exercise hyperpnoea: A synergy of contributions	30
Acute heat stress amplifies exercise‐induced metabolomic perturbations and reveals variation in circulating amino acids in endurance‐trained males	28
Spaceflight and sport science: Physiological monitoring and countermeasures for the astronaut–athlete on Mars exploration missions	26
To Mars through LEO: How commercial space travel will change exploration‐enabling research	26
Dietary manipulations for health and the prevention and management of disease: An editorial	25
The effectiveness of aerobic exercise on pain and disability in individuals with neck pain: A systematic review and meta‐analysis	25
Thermo‐haemodynamic coupling during regional thigh heating: Insight into the importance of local thermosensitive mechanisms in blood circulation	25
When is the right time to initiate rehabilitation? Time will tell…	22
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Low‐load resistance exercise with and without blood flow restriction: Which is more effective for increasing local muscle endurance and why?	22
Downregulation of microRNA‐494 drives mitochondrial biogenesis and function in trained muscle	22
The miRNA‐143‐3p–Sox6–Myh7 pathway is altered in obesogenic diet‐induced cardiac hypertrophy	20
Blunted hypoxic pulmonary vasoconstriction in apnoea divers	20
Muscle fibre size and myonuclear positioning in trained and aged humans	20

No difference in mean middle cerebral artery blood velocity responses between lower‐ and upper‐body unilateral resistance exercise in untrained individuals	19
Network model of skeletal muscle cell signalling predicts differential responses to endurance and resistance exercise training	18
Larger reductions in blood pressure during post‐exercise standing, but not middle cerebral artery blood velocity, in resistance‐trained versus untrained individuals	18
Myths and methodologies: Considerations for evaluating the time course of thermoregulatory adaptation during heat acclimation	18
Interference with glutamate antiporter system xc− enables post‐hypoxic long‐term potentiation in hippocampus	18
Issue Information	17
Issue Information	17
Issue Information	16
From fatigue to physiology: Submaximal 2‐day cardiopulmonary exercise test and emerging standards in long COVID	16
Alpha band oscillations in common synaptic input are explanatory of the complexity of isometric knee extensor muscle torque signals	16
Dynamic cerebral autoregulation quantification with spontaneous arterial blood pressure oscillations: Is transfer function analysis our best option?	16
Kidney function and cognitive impairment	15
Central command suppresses pressor‐evoked bradycardia at the onset of voluntary standing up in conscious cats	15
Unlocking the complications of chronic concussion in rugby players: A traumatic tale of cerebral injury	15
The effect of acute intradermal administration of ascorbate on heat loss responses in older adults with uncomplicated controlled hypertension	15
Limited matching of the cardiac output response to the peripheral demand of heat stress and exercise	14
Is polycystic ovary syndrome associated with elevated muscle sympathetic nerve activity?	14
Habitual exercise in youth: A ʻbrainyʼ idea	14
Effect of adrenaline on serum mid‐regional pro‐atrial natriuretic peptide and central blood volume	14
Even periconceptional alcohol consumption can have long‐term consequences on heart health in the offspring	14
Alveolar deadspace and intrapulmonary shunt in healthy individuals and in individuals who have recovered from COVID‐19 infection	14
Post‐exercise hot or cold water immersion does not alter perception of effort or neuroendocrine responses during subsequent moderate‐intensity exercise	13
Effect of exercise on chronic neck pain and central sensitization: A protocol for a randomized crossover trial	13
On the measurement of glomerular filtration rate: An odyssey into the milieu intérieur	13
Oh G: The x, y and z of human physiological responses to acceleration	13
Editorial Board	13
Handgrip exercise does not alter CO2‐mediated cerebrovascular flow‐mediated dilation	13
Exertional heat stress and intestinal barrier injury: Does chronic disease add fuel to the fire?	13
Effects of tempol on renal medullary tissue hypoxia in an ovine model of Gram‐negative septic acute kidney injury	13
Comparing 17β‐estradiol and progesterone concentrations in young, physically active females: Insights from plasma versus serum analysis	13
Marie Krogh's contributions to the study of thyroid physiology and pathophysiology	13
Mapping the variability of in vivo rat uterine electrical properties throughout the oestrous cycle	13
Challenging dynamic cerebral autoregulation across the physiological CO2 spectrum: Influence of biological sex and cardiac cycle	12
Intestinal epithelial injury and inflammation after physical work in temperate and hot environments in older men with hypertension or type 2 diabetes	12
Skin wound healing as a mirror to cardiac wound healing	12
Delineating the impacts of air temperature and humidity for endurance exercise	12
Diverse perspectives on respiratory chemoreceptor interactions: Resuscitating an expired debate	12
Issue Information	12
Corrigendum	12
Bioenergetic profiles and respiratory control in mitochondrial physiology: Precision analysis of oxidative phosphorylation	12
Sex differences in the coronary vascular response to combined chemoreflex and metaboreflex stimulation in healthy humans	11
DYNamic Assessment of Multi‐Organ level dysfunction in patients recovering from COVID‐19: DYNAMO COVID‐19	11
Peripheral nerve‐derived fibroblasts promote neurite outgrowth in adult dorsal root ganglion neurons more effectively than skin‐derived fibroblasts	11
Exercise‐induced pain within endurance exercise settings: Definitions, measurement, mechanisms and potential interventions	11
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The contribution of the tendon electrode to M‐wave characteristics in the biceps brachii, vastus lateralis and tibialis anterior	11
News, views and where best to choose	11
CTRP6‐mediated cardiac protection in heart failure via the AMPK/SIRT1/PGC‐1α signalling pathway	11
Cardiorespiratory consequences of obesity: a tale of two pumps	11
Characterization of differences in immune responses during bolus and continuous infusion endotoxin challenges using mathematical modelling	11

In support of the placental programming hypothesis: Placental endocrine insufficiency programs atypical behaviour in mothers and their offspring	11
On changes, challenges and collaboration: Introducing a new Editor‐in‐Chief and moving to Open Access	11
Association between effective neural drive to the triceps surae and fluctuations in plantar‐flexion torque during submaximal isometric contractions	10
The severity of acute hypoxaemia determines distinct changes in intracortical and spinal neural circuits	10
Short‐term effects of electronic cigarettes on cerebrovascular function: A time course study	10
‘One for all, all for one’: A tale from the formative years of Scandinavian exercise physiology	10
Insulin‐like growth factor‐1 infusion in preterm piglets does not affect growth parameters of skeletal muscle or tendon tissue	10
Response to the letter from Bushfield and Day: Potential pitfalls of using a correction to normative values in the assessment of acid–base compensation during early ascent to high altitude	10
Effect of artificial gravity on calcaneal bone marrow adipose tissue and mineral content in female and male participants in 60 days of bed rest	10
Effect of moderate altitude and nocturnal oxygen therapy on cerebrovascular function in patients with COPD: A randomized, crossover trial at 2048 m	9
A new method for non‐invasive determination of effective pulmonary blood flow and cardiac output in spontaneously breathing subjects	9
RETRACTED: Corrigendum	9
Editorial Board	9
Distinct adaptations of muscle endurance but not strength or hypertrophy to low‐load resistance training with and without blood flow restriction	9
GST polymorphism as a predictive biomarker for modulating the susceptibility to chronic obstructive pulmonary disease: A North Indian study	9
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A crossover control study of three methods of heat acclimation on the magnitude and kinetics of adaptation	9
Issue Information	9
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The acute effects of dynamic stretching on the neuromuscular system are independent of the velocity	9
The role of orexin A in the pathogenesis of ischaemic stroke at high altitude	9
The impact of long‐haul travel and 13 h time change on sleep and rest activity circadian rhythm in speed skaters during World Cup competitions	9
Impaired glucose tolerance and insulin resistance in a prenatally‐androgenized rat model of polycystic ovary syndrome in later life	9
Impact of whole‐body resistance exercise timing on mitigating hyperglycaemia‐induced vascular dysfunction	8
Inhibitory effect of oestradiol on the cardiac KV7.1/KCNE1 channel is species dependent	8
Caffeine in cerebrovascular research: To withdraw or not to withdraw?	8
Gut microbiota in regulation of childhood bone growth	8
Pulmonary vascular reactivity to supplemental oxygen in Sherpa and lowlanders during gradual ascent to high altitude	8
Acute alterations in blood lactate in the setting of transient stress induced myocardial ischaemia	8
Defying gravity: Breath, beat and brain	8
Role of RIPK1/RIPK3/MLKL signalling pathway in sepsis‐associated acute kidney injury	8
Maximal strength and voluntary activation of adductor pollicis after a single session of acute intermittent hypercapnia or acute intermittent hypoxia	8
Functional assays reflective of cancer hallmarks in BT‐549 cells are not impacted by media supplemented with exercise‐trained plasma	8
A single breath of nitric oxide does not alter pulmonary perfusion pressure	8
Differential intestinal injury and unchanged systemic inflammatory responses to leg and whole‐body passive hyperthermia in healthy humans	8
Temporal summation in human peripheral axons when stimulated transcutaneously with a 10‐kHz waveform	8
Changes in motor unit behaviour across repeated bouts of eccentric exercise	8
Sex‐dependent effects of a high‐fat diet‐induced obesity model on cerebrovascular health and brain metabolism	8
The acute effect of a laboratory shame induction protocol on endothelial function in young, healthy adults	8
Knee movements cause changes in the firing behaviour of muscle spindles located within the mono‐articular ankle extensor soleus in the rat	7
Acute high‐intensity muscle contraction moderates AChR gene expression independent of rapamycin‐sensitive mTORC1 pathway in rat skeletal muscle	7
Computing muscle mechanical state variables from combined proprioceptive sensory feedback	7
Spectral changes in skin blood flow during pressure manipulations or sympathetic stimulation	7
Sex differences in the ventilatory responses to exercise in mild to moderate obesity	7
The effect of protein or amino acid provision on immobilization‐induced muscle atrophy in healthy adults: A systematic review and meta‐analysis	7
Heat and carbon monoxide exposure: Is two better than one?	7
Effect of internal and external cooling on high‐intensity intermittent cycling performance and cognitive function in the heat	7
Oral ketone monoester supplementation does not accelerate recovery of muscle force or modulate circulating cytokine concentrations after muscle‐damaging eccentric exercise in healthy males and females	7
Lower vascular conductance responses to handgrip exercise are improved following acute antioxidant supplementation in young individuals with post‐traumatic stress disorder	7
Obesity and exercise training alter inflammatory pathway skeletal muscle small extracellular vesicle microRNAs	7
Use of transcutaneous spinal cord stimulation to explore inhibitory and facilitatory circuits in muscles of the human lower limb	7
Effect of high‐fat diet on isometric, concentric and eccentric contractile performance of skeletal muscle isolated from female CD‐1 mice	7
Memory impairment in the D2.mdx mouse model of Duchenne muscular dystrophy is prevented by the adiponectin receptor agonist ALY688	7
Issue Information	7
Vascular limitations in blood pressure regulation with age in women: Insights from exercise and acute cardioselective β‐blockade	7
Issue Information	7
Changes in cerebral autoregulation and vasoreactivity after surgical aortic valve replacement: a prospective study	7
Elite sport, innovation and the application gap	7
Issue Information	7
Beyond the horizon: Why space biology is the next great innovation opportunity	6
The differential sensitivity of the hypothalamic–hypophysial–ovarian axis to 5‐hydroxytryptophan alters the secretion of estradiol	6
Climate change, healthy ageing and the health crisis: is wisdom the link?	6
From discovery to innovation in physiological research	6
Cell‐free DNA kinetics in response to muscle‐damaging exercise: A drop jump study	6
Issue Information	6
ZDF (fa/fa) rats show increasing heterogeneity in main parameters during ageing, as confirmed by biometrics, oxidative stress markers and MMP activity	6
Cerebral haemodynamic responses to inspiratory muscle work	6
Exercise‐induced effects on atherogenesis and tryptophan catabolism via the kynurenine pathway in an HIV‐associated atherosclerosis mouse model	6
Sarcoplasmic reticulum calcium handling in unbranched, immediately post‐necrotic fast‐twitch mdx fibres is similar to wild‐type littermates	6
Breath‐by‐breath measurement of alveolar gas exchange must preserve mass balance and conform to a physiological definition of a breath	6
Exercise oximetry in clinical practice: A single‐centre perspective on procedure and techniques	6
Submaximal 2‐day cardiopulmonary exercise testing to assess exercise capacity and post‐exertional symptom exacerbation in people with long COVID	6
Control of blood pressure in the cold: differentiation of skin and skeletal muscle vascular resistance	6
Galectin‐3 and suppression of tumorigenicity 2: Two emerging cardiac biomarkers that may be predictors of cardiac fibrosis development in sport	6
Stabilising function of the human diaphragm in response to involuntary augmented breaths induced with or without lower‐limb movements	6
Epigenetic responses to heat: From adaptation to maladaptation	6
Acute intermittent hypoxia in neonatal rodent central nervous system facilitates respiratory frequency through the recruitment of hypothalamic areas	6
Spontaneous Ca2+ signals in the developing mammalian cochlea of live mice under different anaesthetic regimes	6
Data analysis technique influences blood flow kinetics parameter estimates for moderate‐ and heavy‐intensity exercise transitions	6
Energy expenditure, intake and availability in female soccer players via doubly labelled water: Are we misrepresenting low energy availability?	6

Applying lessons from limb muscle disuse and ageing to better understand ventilator‐induced diaphragm dysfunction	6
Lower limb hyperthermia augments functional hyperaemia during small muscle mass exercise similarly in trained elderly and young humans	6
Why is the muscle spindle so complicated?	6
Impact of a 12‐week high‐intensity interval training intervention on cardiac structure and function after COVID‐19 at 12‐month follow‐up	6
Myths and methodologies: Assessing glycaemic control and associated regulatory mechanisms in human physiology research	6
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The effect of exercise in a fasted state on plasma low‐density lipoprotein cholesterol concentrations in males and females	6
Biomarkers of heatstroke‐induced organ injury and repair	6
Pulmonary diffusing capacity to nitric oxide and carbon monoxide during exercise and in the supine position: a test–retest reliability study	6
Computational study of the excitation of human induced pluripotent stem cell‐derived cardiomyocytes	6
Issue Information	6
Exercise in hypobaric hypoxia increases markers of intestinal injury and symptoms of gastrointestinal distress	6
The effect of acute intermittent hypoxia on human limb motoneurone output	6
The renal vasodilatation from β‐adrenergic activation in vivo in rats is not driven by KV7 and BKCa channels	6
Individual assessment of ventilatory acclimatization at high altitude	6
Effects of hyperprotein diet on anxiety, haemodynamics and morphofunctional aspects of the heart of Wistar rats	5
A comparison between left ventricular ejection time measurement methods during physiological changes induced by simulated microgravity	5
Blood flow restriction training attenuates changes in local muscle endurance: At odds with previous work?	5
Vascular, inflammatory and perceptual responses to hot water immersion: Impacts of water depth and temperature in young healthy adults	5
Exertional heat stroke: nutritional considerations	5
NEX4EX – A novel exercise device enabling resistive, plyometric and sensorimotor training during deep‐space missions: A case report	5
The effect of female breast surface area on skin stiffness and tactile sensitivity at rest and following exercise in the heat	5
Directional sensitivity of the cerebral pressure–flow relationship in young healthy individuals trained in endurance and resistance exercise	5
The inaugural ‘Mid‐Career Researcher’ prize: Rewarding and acknowledging future leaders in physiology	5
Preserved force control by the digits via minimal sparing of cortico‐spinal connectivity after stroke	5
Is the blood pressure response to exercise associated with the motor unit firing patterns of the exercised muscle?	5
Physiology of lived experience: Boston wrong: A series of physiological calamities at the Boston Marathon	5
Acute and long‐term effect of specific and non‐specific exercises in patients with chronic neck pain: A protocol for a randomized controlled trial	5
Blood flow restriction exercise during microgravity exposure in parabolic flight	5
Race and ethnicity in physiological research: When socio‐political constructs and biology collide	5
Klotho, the Greek goddess controlling the fate of skeletal muscle satellite cells	5
Locomotor muscle dysfunction and rehabilitative exercise training in fibrotic interstitial lung disease: Where are we at and where could we go?	5
Issue Information	5
The sympathetic nervous system in healthy and hypertensive pregnancies: physiology or pathology?	5
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TRPV1 blockade restores the baroreflex control of renal sympathetic nerve activity in cisplatin‐induced renal injury in rats	5
Death by nitrogen anoxia: On the integrated physiology of human execution	5
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Reply to Veerkamp et al.: Comments on Harkness‐Armstrong et al. (2021)	5
Cardiovascular and respiratory evaluation in adenosine A2A receptor knockout mice submitted to short‐term sustained hypoxia	5
Measuring pulmonary oxygen uptake kinetics: Contemporary perspectives	5
Durability as an index of endurance exercise performance: Methodological considerations	5
Interleukin‐15 receptor subunit alpha regulates interleukin‐15 localization and protein expression in skeletal muscle cells	5
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Using modified Fenn diagrams to assess ventilatory acclimatization during ascent to high altitude: Effect of acetazolamide	5
Synbiotic supplementation ameliorates anxiety and myocardial ischaemia–reperfusion injury in hyperglycaemic rats by modulating gut microbiota	5
Water and wisdom: Hydration as a defence against dementia	5
Skin wetness perception across body sites in children and adolescents aged 7–16 years old	5
Artificial intelligence driven clustering of blood pressure profiles reveals frailty in orthostatic hypertension	5
Issue Information	5
Diffusion and physical constraints limit oxidative capacity, capillary supply and size of muscle fibres in mice and humans	4
Effects of repeated cryostimulation exposures on sleep quality in swimmers during an intense training period	4
Membrane progesterone and oestrogen receptors modulate GABAergic transmission in the prefrontal cortex of prepubertal male, but not female, mice	4
Blistering barnacles: Space physiology in The Adventures of Tintin	4
Intensified training augments cardiac function, but not blood volume, in male youth elite ice hockey team players	4
Uncovering the impact of the cardiovascular system on cerebrovascular health using MRI	4
Melanin‐concentrating hormone regulates the hypercapnic chemoreflex by acting in the lateral hypothalamic area	4
Early chronotype with metabolic syndrome favours resting and exercise fat oxidation in relation to insulin‐stimulated non‐oxidative glucose disposal	4
Acute neuromuscular, cardiovascular, and muscle oxygenation responses to low‐intensity aerobic interval exercises with blood flow restriction	4
Physical exercise intervention in glycogen storage disease IIIa: Feasibility and multisystem benefits	4
One minute of light‐intensity stair‐stepping decreases postprandial glycaemia in the evening in non‐diabetic adults: A randomized controlled trial	4
Protein‐based perioperative nutrition interventions for improving muscle mass and functional outcomes following orthopaedic surgery	4
Early life stress and hormonal status influence orexin‐1 receptor expression in structures regulating cardiorespiratory responses to CO2	4
Possible protective effect of zinc administration on renal and cognitive changes occurring in uninephrectomized adult male Wistar rats	4
A new method for bedside determination of effective lung volume and functional residual capacity	4
Frequency responses of human magnetophosphene perception thresholds during dark adaptation point to rod modulation	4
Relationship between neuromuscular fatigue, muscle activation and the work done above the critical power during severe‐intensity exercise	4
Is there reversible dimerization of albumin in blood plasma? And does it matter?	4
The mood stabilizers lithium and valproate disrupt hepatic and intestinal farnesoid X receptor signalling and increase bile synthesis in the rat	4
Expression characteristics of dual‐specificity phosphatase 2 and hypoxia‐inducible factor‐1α in acute kidney injury and preliminary study of the effect of dual‐specificity phosphatase 2 on HK‐2 cells	4
The evolution of muscle spindles	4
Insights into pathophysiology and therapeutic strategies for heat stroke: Lessons from a baboon model	4
LGD‐4033 and MK‐677 use impacts body composition, circulating biomarkers, and skeletal muscle androgenic hormone and receptor content: A case report	4
Reflections on physiology and modelling	4
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Clinical significance and immune microenvironment association of cuproptosis‐related genes in pan‐cancer	4
Attenuation of muscle spindle firing with artificially increased series compliance during stretch of relaxed muscle	4
Consistency of endothelial function across two consecutive oral contraceptive pill cycles	4
On the challenge of assessing dynamic cerebral autoregulation	4
Respiratory muscle metaboreflex: Connecting the ‘dots’	4
Physiological influences on neurovascular coupling: A systematic review of multimodal imaging approaches and recommendations for future study designs	4
Making sense of the carotid body counter‐regulatory response to hypoglycaemia	4
Circadian rhythm of brain‐derived neurotrophic factor in serum and plasma	4
Effect of prolonged sitting on dynamic cerebral autoregulation in the anterior and posterior cerebral circulations	4
Issue Information	4
Exercise breaks prevent attenuation in cerebrovascular function following an acute bout of uninterrupted sitting in healthy children	4
Issue Information	4
Role of proprioceptors in chronic musculoskeletal pain	4
Implementation of a coagulation component into a phosphate kinetics model in haemodialysis therapy: A tool for detection of clotting problems?	4
Acute effects of insulin and insulin‐induced hypoglycaemia on carotid body chemoreceptor activity and cardiorespiratory responses in dogs	4
Size, more than oxygen need, determines the number of capillaries around a muscle fibre	4
Faecal microbiome, gastrointestinal integrity, inflammation and thermoregulation in recent exertional heat illness patients and matched controls	4
Evaluation of metabolism‐related molecules in rat model of autism spectrum disorders	4
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Immediate cortical glial alterations following spinal cord injury: Evidence from a novel in vitro model	4