Experimental Physiology

Article	Citations
Chasing genes at high‐altitude	185
Physiological assessment of a 16 day, 4385 km ultra‐endurance mountain bike race: A case study	97
To Mars through LEO: How commercial space travel will change exploration‐enabling research	77
Dietary manipulations for health and the prevention and management of disease: An editorial	61
Mechanosensory encoding in ex vivo muscle–nerve preparations	52
Applying thermal therapy: Comparison of different commercially available heating devices to increase muscle temperature	43
The miRNA‐143‐3p–Sox6–Myh7 pathway is altered in obesogenic diet‐induced cardiac hypertrophy	39
No difference in mean middle cerebral artery blood velocity responses between lower‐ and upper‐body unilateral resistance exercise in untrained individuals	37
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Larger reductions in blood pressure during post‐exercise standing, but not middle cerebral artery blood velocity, in resistance‐trained versus untrained individuals	34
Low‐load resistance exercise with and without blood flow restriction: Which is more effective for increasing local muscle endurance and why?	31
Acute heat stress amplifies exercise‐induced metabolomic perturbations and reveals variation in circulating amino acids in endurance‐trained males	31
How do physiological networks respond to normobaric hypoxia and isometric exercise?	29
The physiology of survival: Fluid and food	27
When is the right time to initiate rehabilitation? Time will tell…	25
Myths and methodologies: Considerations for evaluating the time course of thermoregulatory adaptation during heat acclimation	24
Muscle fibre size and myonuclear positioning in trained and aged humans	22
Blunted hypoxic pulmonary vasoconstriction in apnoea divers	22
Chitinase 3‐like 1 overexpression aggravates hypoxia–reoxygenation injury in IEC‐6 cells by inhibiting the PI3K/AKT signalling pathway	22
Thermo‐haemodynamic coupling during regional thigh heating: Insight into the importance of local thermosensitive mechanisms in blood circulation	21
Interference with glutamate antiporter system xc− enables post‐hypoxic long‐term potentiation in hippocampus	21
Nitrite supplementation alleviates cerebrovascular dysfunction in chronically stressed mice, but cognitive decline remains	21
ZFP36 inhibits the pro‐apoptotic effects of transforming growth factor β1 on mitral valve interstitial cells via the GTP‐binding protein 6 pathway in mitral valve prolapse	20
Downregulation of microRNA‐494 drives mitochondrial biogenesis and function in trained muscle	19
Network model of skeletal muscle cell signalling predicts differential responses to endurance and resistance exercise training	19

Beyond single stressors/stimuli in adaptive physiology: Dose–response relationships and translational challenges	19
Using environmental and exercise physiology to address gender inequalities in climate change and occupational health research	18
Acute partial sleep restriction does not impact arterial function in young and healthy humans	18
Spaceflight and sport science: Physiological monitoring and countermeasures for the astronaut–athlete on Mars exploration missions	18
Moderate maternal nutrient restriction alters type II alveolar epithelial cell density in the non‐human primate fetal lung	18
Issue Information	17
Issue Information	17
The effectiveness of aerobic exercise on pain and disability in individuals with neck pain: A systematic review and meta‐analysis	17
The effect of acute intradermal administration of ascorbate on heat loss responses in older adults with uncomplicated controlled hypertension	16
Kidney function and cognitive impairment	16
Alpha band oscillations in common synaptic input are explanatory of the complexity of isometric knee extensor muscle torque signals	16
Central command suppresses pressor‐evoked bradycardia at the onset of voluntary standing up in conscious cats	16
Issue Information	16
Habitual exercise in youth: A ʻbrainyʼ idea	15
Unlocking the complications of chronic concussion in rugby players: A traumatic tale of cerebral injury	15
From fatigue to physiology: Submaximal 2‐day cardiopulmonary exercise test and emerging standards in long COVID	14
Comparing 17β‐estradiol and progesterone concentrations in young, physically active females: Insights from plasma versus serum analysis	14
Post‐exercise hot or cold water immersion does not alter perception of effort or neuroendocrine responses during subsequent moderate‐intensity exercise	14
Marie Krogh's contributions to the study of thyroid physiology and pathophysiology	14
Passive thigh heating improves peak force production in younger adults and early isokinetic force production in younger and older adults	14
Effect of adrenaline on serum mid‐regional pro‐atrial natriuretic peptide and central blood volume	14
Handgrip exercise does not alter CO2‐mediated cerebrovascular flow‐mediated dilation	14
Mapping the variability of in vivo rat uterine electrical properties throughout the oestrous cycle	14
Even periconceptional alcohol consumption can have long‐term consequences on heart health in the offspring	14
From SilverStar to shining stars: Physiology's next generation	14
Is polycystic ovary syndrome associated with elevated muscle sympathetic nerve activity?	14
Issue Information	14
Limited matching of the cardiac output response to the peripheral demand of heat stress and exercise	13
Effects of tempol on renal medullary tissue hypoxia in an ovine model of Gram‐negative septic acute kidney injury	13
On the measurement of glomerular filtration rate: An odyssey into the milieu intérieur	13
Dynamic cerebral autoregulation quantification with spontaneous arterial blood pressure oscillations: Is transfer function analysis our best option?	13
Impact of heat exposure during immobilization‐induced de‐training and re‐training on aerobic capacity and haemoglobin mass	13
The physiology of survival: Breath‐hold shallow‐water diving	13
Alveolar deadspace and intrapulmonary shunt in healthy individuals and in individuals who have recovered from COVID‐19 infection	13
Acute cardiovascular responses to slow and deep breathing in normotensive men and women	13
Issue Information	12
Delineating the impacts of air temperature and humidity for endurance exercise	12
Issue Information	12
On changes, challenges and collaboration: Introducing a new Editor‐in‐Chief and moving to Open Access	12
Diverse perspectives on respiratory chemoreceptor interactions: Resuscitating an expired debate	12
Exertional heat stress and intestinal barrier injury: Does chronic disease add fuel to the fire?	12
Reply to letter to the editor in response to: “Carbon monoxide to ‘simulate altitude’”	12
Short‐term effects of electronic cigarettes on cerebrovascular function: A time course study	12
Intestinal epithelial injury and inflammation after physical work in temperate and hot environments in older men with hypertension or type 2 diabetes	12
Effect of exercise on chronic neck pain and central sensitization: A protocol for a randomized crossover trial	12
Skeletal muscle mitochondrial marker responses to a single bout and 6 weeks of high load versus high volume resistance training in previously trained men	11
News, views and where best to choose	11
Characterization of differences in immune responses during bolus and continuous infusion endotoxin challenges using mathematical modelling	11
GABA B receptor‐mediated modulation of sensory neuron excitability: Roles of Ca V 2.2, G‐protein‐c	11
Insulin‐like growth factor‐1 infusion in preterm piglets does not affect growth parameters of skeletal muscle or tendon tissue	11

Effects of bed rest and immobilization on intramuscular and intermuscular adipose tissue: A systematic review	11
Cardiorespiratory consequences of obesity: a tale of two pumps	11
Exercise‐induced pain within endurance exercise settings: Definitions, measurement, mechanisms and potential interventions	11
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Response to the letter from Bushfield and Day: Potential pitfalls of using a correction to normative values in the assessment of acid–base compensation during early ascent to high altitude	11
The severity of acute hypoxaemia determines distinct changes in intracortical and spinal neural circuits	11
‘One for all, all for one’: A tale from the formative years of Scandinavian exercise physiology	11
The role of orexin A in the pathogenesis of ischaemic stroke at high altitude	11
The contribution of the tendon electrode to M‐wave characteristics in the biceps brachii, vastus lateralis and tibialis anterior	11
Skin wound healing as a mirror to cardiac wound healing	11
A comparison of normobaric and hypobaric hypoxia effects on cerebrovascular response pre and post maximal exercise	11
Peripheral nerve‐derived fibroblasts promote neurite outgrowth in adult dorsal root ganglion neurons more effectively than skin‐derived fibroblasts	11
Effect of artificial gravity on calcaneal bone marrow adipose tissue and mineral content in female and male participants in 60 days of bed rest	11
Immunomodulatory effects of cathelicidin in the gut–brain axis: A novel link between mucosal immunity and neuroinflammation	10
Challenging dynamic cerebral autoregulation across the physiological CO2 spectrum: Influence of biological sex and cardiac cycle	10
Issue Information	10
Defying gravity: Breath, beat and brain	10
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CTRP6‐mediated cardiac protection in heart failure via the AMPK/SIRT1/PGC‐1α signalling pathway	10
The impact of long‐haul travel and 13 h time change on sleep and rest activity circadian rhythm in speed skaters during World Cup competitions	10
Optimizing cerebrovascular endothelial health through shear stress modulation	10
Inhibitory effect of oestradiol on the cardiac K V 7.1/KCNE1 channel is species dependent	10
Bioenergetic profiles and respiratory control in mitochondrial physiology: Precision analysis of oxidative phosphorylation	10
DYNamic Assessment of Multi‐Organ level dysfunction in patients recovering from COVID‐19: DYNAMO COVID‐19	10
Contemporary concepts in ‘exercise as medicine’ and related fields	10
Impaired glucose tolerance and insulin resistance in a prenatally‐androgenized rat model of polycystic ovary syndrome in later life	10
Acute alterations in blood lactate in the setting of transient stress induced myocardial ischaemia	10
Pulmonary vascular reactivity to supplemental oxygen in Sherpa and lowlanders during gradual ascent to high altitude	9
RETRACTED: Corrigendum	9
Role of RIPK1/RIPK3/MLKL signalling pathway in sepsis‐associated acute kidney injury	9
Changes in motor unit conduction velocity after unilateral lower‐limb suspension and active recovery are correlated with muscle ion channel gene expression	9
A new method for non‐invasive determination of effective pulmonary blood flow and cardiac output in spontaneously breathing subjects	9
The acute effects of dynamic stretching on the neuromuscular system are independent of the velocity	9
Functional assays reflective of cancer hallmarks in BT‐549 cells are not impacted by media supplemented with exercise‐trained plasma	9
Effect of moderate altitude and nocturnal oxygen therapy on cerebrovascular function in patients with COPD: A randomized, crossover trial at 2048 m	9
Ghrelin protects against cell death in myocardial ischaemia: Emerging role of microRNA	9
A single breath of nitric oxide does not alter pulmonary perfusion pressure	9
Oral ketone monoester supplementation does not accelerate recovery of muscle force or modulate circulating cytokine concentrations after muscle‐damaging eccentric exercise in healthy males and females	9
Maximal strength and voluntary activation of adductor pollicis after a single session of acute intermittent hypercapnia or acute intermittent hypoxia	9
From mechanistic promise to clinical translation: Passive heat therapy as a cardiovascular and functional adjunct in ageing and disease	9
Changes in motor unit behaviour across repeated bouts of eccentric exercise	9
The impact of type 2 diabetes on tendon material properties and locomotor function in the db / db mouse	9
GST polymorphism as a predictive biomarker for modulating the susceptibility to chronic obstructive pulmonary disease: A North Indian study	9
Temporal summation in human peripheral axons when stimulated transcutaneously with a 10‐kHz waveform	9
Prespecified analysis plans are not suitable for exploratory experimental physiology research	9
Gut microbiota in regulation of childhood bone growth	9
Passive hyperthermia increases blood circulation in specific regions, largely independent of conduit artery mechanics and cardiac performance	8
Sex differences in the ventilatory responses to exercise in mild to moderate obesity	8
ZDF (fa/fa) rats show increasing heterogeneity in main parameters during ageing, as confirmed by biometrics, oxidative stress markers and MMP activity	8
Issue Information	8
Cerebral haemodynamic responses to inspiratory muscle work	8
Issue Information	8
The maturation of regional sweating patterns from childhood to young adulthood in females	8
Distinct adaptations of muscle endurance but not strength or hypertrophy to low‐load resistance training with and without blood flow restriction	8
Modulation of cerebral blood flow and cognition by hyperthermia and hypoxia: An electroencephalographic event‐related potentials perspective	8
Issue Information	8
Acute high‐intensity muscle contraction moderates AChR gene expression independent of rapamycin‐sensitive mTORC1 pathway in rat skeletal muscle	8
Applying lessons from limb muscle disuse and ageing to better understand ventilator‐induced diaphragm dysfunction	8
Knee movements cause changes in the firing behaviour of muscle spindles located within the mono‐articular ankle extensor soleus in the rat	8
Issue Information	8
Vascular limitations in blood pressure regulation with age in women: Insights from exercise and acute cardioselective β‐blockade	8
The acute effect of a laboratory shame induction protocol on endothelial function in young, healthy adults	8
Heat and carbon monoxide exposure: Is two better than one?	8
Caffeine in cerebrovascular research: To withdraw or not to withdraw?	8
Effect of high‐fat diet on isometric, concentric and eccentric contractile performance of skeletal muscle isolated from female CD‐1 mice	8
Spectral changes in skin blood flow during pressure manipulations or sympathetic stimulation	8
Changes in cerebral autoregulation and vasoreactivity after surgical aortic valve replacement: a prospective study	8
The effect of protein or amino acid provision on immobilization‐induced muscle atrophy in healthy adults: A systematic review and meta‐analysis	8
Effect of internal and external cooling on high‐intensity intermittent cycling performance and cognitive function in the heat	8
Differential intestinal injury and unchanged systemic inflammatory responses to leg and whole‐body passive hyperthermia in healthy humans	8
The principles of systems biology	8
Sex‐dependent effects of a high‐fat diet‐induced obesity model on cerebrovascular health and brain metabolism	8
Galectin‐3 and suppression of tumorigenicity 2: Two emerging cardiac biomarkers that may be predictors of cardiac fibrosis development in sport	7
Synbiotic supplementation ameliorates anxiety and myocardial ischaemia–reperfusion injury in hyperglycaemic rats by modulating gut microbiota	7
Breath‐by‐breath measurement of alveolar gas exchange must preserve mass balance and conform to a physiological definition of a breath	7
Acute intermittent hypoxia in neonatal rodent central nervous system facilitates respiratory frequency through the recruitment of hypothalamic areas	7
The sympathetic nervous system in healthy and hypertensive pregnancies: physiology or pathology?	7
Memory impairment in the D2.mdx mouse model of Duchenne muscular dystrophy is prevented by the adiponectin receptor agonist ALY688	7
Control of blood pressure in the cold: differentiation of skin and skeletal muscle vascular resistance	7
Passive heat intervention research in women: Systematic review and audit of female representation	7

The renal vasodilatation from β‐adrenergic activation in vivo in rats is not driven by KV7 and BKCa channels	7
Dietary interventions in acute kidney injury: From molecular mechanism to clinical trials	7
Potential pitfalls of using a correction to normative values for the assessment of acid–base compensation during early ascent to high altitude	7
Lower limb hyperthermia augments functional hyperaemia during small muscle mass exercise similarly in trained elderly and young humans	7
Neuromuscular fatigue and loss of torque complexity during severe‐intensity exercise: The role of muscle size	7
Myths and methodologies: Assessing glycaemic control and associated regulatory mechanisms in human physiology research	7
Stabilising function of the human diaphragm in response to involuntary augmented breaths induced with or without lower‐limb movements	7
Exercise oximetry in clinical practice: A single‐centre perspective on procedure and techniques	7
Why is the muscle spindle so complicated?	7
Issue Information	7
Exercise‐induced effects on atherogenesis and tryptophan catabolism via the kynurenine pathway in an HIV‐associated atherosclerosis mouse model	7
Cerebral oxygenation and skeletal muscle responses to time trial, maximal oxygen uptake and time to exhaustion exercise	7
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Use of transcutaneous spinal cord stimulation to explore inhibitory and facilitatory circuits in muscles of the human lower limb	7
Individual assessment of ventilatory acclimatization at high altitude	7
Computing muscle mechanical state variables from combined proprioceptive sensory feedback	7
Computational study of the excitation of human induced pluripotent stem cell‐derived cardiomyocytes	7
Lower vascular conductance responses to handgrip exercise are improved following acute antioxidant supplementation in young individuals with post‐traumatic stress disorder	7
Climate change, healthy ageing and the health crisis: is wisdom the link?	7
Cardiopulmonary function in special operations forces compared to conventional infantry soldiers	7
From discovery to innovation in physiological research	7
The effect of female breast surface area on skin stiffness and tactile sensitivity at rest and following exercise in the heat	7
Beyond the horizon: Why space biology is the next great innovation opportunity	7
Biomarkers of heatstroke‐induced organ injury and repair	7
The effect of artificial gravity on the outcome of a two‐week resistance vibration exercise programme: BRAVE study	7
Integrative regulation of cerebral blood flow in response to exercise and environmental extremes	7
The effect of exercise in a fasted state on plasma low‐density lipoprotein cholesterol concentrations in males and females	7
Cell‐free DNA kinetics in response to muscle‐damaging exercise: A drop jump study	7
Energy expenditure, intake and availability in female soccer players via doubly labelled water: Are we misrepresenting low energy availability?	7
Spontaneous Ca 2+ signals in the developing mammalian cochlea of live mice under different anaesthetic regimes	7
NEX4EX – A novel exercise device enabling resistive, plyometric and sensorimotor training during deep‐space missions: A case report	7
Blood flow restriction training attenuates changes in local muscle endurance: At odds with previous work?	6
A comparison of the neuromuscular, cardiopulmonary and muscle oxygenation responses to single‐ and double‐leg cycling in older adults	6
Physiology of lived experience: Boston wrong: A series of physiological calamities at the Boston Marathon	6
Cerebral blood flow regulation, central arterial stiffness and traumatic brain injury: Effects of aerobic exercise training	6
On the mechanism of control of the pulse rate	6
Klotho, the Greek goddess controlling the fate of skeletal muscle satellite cells	6
Small muscle mass aerobic exercise in health and disease: Unique insights into muscle vascular and metabolic control and performance	6
Submaximal 2‐day cardiopulmonary exercise testing to assess exercise capacity and post‐exertional symptom exacerbation in people with long COVID	6
Using modified Fenn diagrams to assess ventilatory acclimatization during ascent to high altitude: Effect of acetazolamide	6
Issue Information	6
Effects of hyperprotein diet on anxiety, haemodynamics and morphofunctional aspects of the heart of Wistar rats	6
Making sense of the carotid body counter‐regulatory response to hypoglycaemia	6
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Preserved force control by the digits via minimal sparing of cortico‐spinal connectivity after stroke	6
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TRPV1 blockade restores the baroreflex control of renal sympathetic nerve activity in cisplatin‐induced renal injury in rats	6
Skin wetness perception across body sites in children and adolescents aged 7–16 years old	6
Glycosylation of the murine cardiac channel TRPM4 is altered by the pathogenic p.I376T variant	6
Blood flow restriction exercise during microgravity exposure in parabolic flight	6
Impact of a 12‐week high‐intensity interval training intervention on cardiac structure and function after COVID‐19 at 12‐month follow‐up	6
Passive heat therapy is feasible but does not affect cardiometabolic health outcomes in persons with spinal cord injury – a pilot study	6
The importance of high‐quality heat adaptation research in females	6
Vascular, inflammatory and perceptual responses to hot water immersion: Impacts of water depth and temperature in young healthy adults	6
Acute and long‐term effect of specific and non‐specific exercises in patients with chronic neck pain: A protocol for a randomized controlled trial	6
Respiratory muscle metaboreflex: Connecting the ‘dots’	6
Issue Information	6
Durability as an index of endurance exercise performance: Methodological considerations	6
Effect of live‐high, train‐low strategy induced by chronic low‐dose carbon monoxide exposure on haematological parameters and performance in trained individuals	6
Race and ethnicity in physiological research: When socio‐political constructs and biology collide	6
Cardiovascular and respiratory evaluation in adenosine A2A receptor knockout mice submitted to short‐term sustained hypoxia	6
Measuring pulmonary oxygen uptake kinetics: Contemporary perspectives	6
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Pulmonary diffusing capacity to nitric oxide and carbon monoxide during exercise and in the supine position: a test–retest reliability study	6
The differential sensitivity of the hypothalamic–hypophysial–ovarian axis to 5‐hydroxytryptophan alters the secretion of estradiol	6
Water and wisdom: Hydration as a defence against dementia	6
Daily hot‐water immersion preserves altitude‐induced haemoglobin mass expansion following descent independent of erythropoietin	6
A change to Experimental Physiology’s statistics policy	6
Reply to Veerkamp et al.: Comments on Harkness‐Armstrong et al. (2021)	6
Locomotor muscle dysfunction and rehabilitative exercise training in fibrotic interstitial lung disease: Where are we at and where could we go?	6
Frequency responses of human magnetophosphene perception thresholds during dark adaptation point to rod modulation	5
Early chronotype with metabolic syndrome favours resting and exercise fat oxidation in relation to insulin‐stimulated non‐oxidative glucose disposal	5
Is there reversible dimerization of albumin in blood plasma? And does it matter?	5
Acute neuromuscular, cardiovascular, and muscle oxygenation responses to low‐intensity aerobic interval exercises with blood flow restriction	5
Estimated exercise‐induced maximal myocardial blood flow in untrained and endurance‐trained men	5
Implementation of a coagulation component into a phosphate kinetics model in haemodialysis therapy: A tool for detection of clotting problems?	5
Blistering barnacles: Space physiology in The Adventures of Tintin	5
Adaptive mediolateral control during split‐belt walking: Energetics of interlimb coordination and enhanced savings following acute intermittent hypoxia	5
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Acute metabolic responses to high‐intensity interval training in men with overweight or obesity: Does the exercise modality matter?	5
Therapeutic potential of okra ( Abelmoschus esculentus ) in dysglycaemia and metabolic dysfunction: A systematic review and meta‐analysis across the diab	5
Size, more than oxygen need, determines the number of capillaries around a muscle fibre	5
Reflections on physiology and modelling	5
Issue Information	5
Possible protective effect of zinc administration on renal and cognitive changes occurring in uninephrectomized adult male Wistar rats	5
Attenuation of muscle spindle firing with artificially increased series compliance during stretch of relaxed muscle	5
Physical exercise intervention in glycogen storage disease IIIa: Feasibility and multisystem benefits	5
LGD‐4033 and MK‐677 use impacts body composition, circulating biomarkers, and skeletal muscle androgenic hormone and receptor content: A case report	5
Physiological influences on neurovascular coupling: A systematic review of multimodal imaging approaches and recommendations for future study designs	5
Membrane progesterone and oestrogen receptors modulate GABAergic transmission in the prefrontal cortex of prepubertal male, but not female, mice	5
Circadian rhythm of brain‐derived neurotrophic factor in serum and plasma	5
Evaluation of metabolism‐related molecules in rat model of autism spectrum disorders	5
Expression characteristics of dual‐specificity phosphatase 2 and hypoxia‐inducible factor‐1α in acute kidney injury and preliminary study of the effect of dual‐specificity phosphatase 2 on HK‐2 cells	5
On the challenge of assessing dynamic cerebral autoregulation	5
Oxygen diffusion kinetics, buffering capacity and phenotype: A narrative review of oxygen physiology and later phenotype in very preterm infants	5