Current Opinion in Biotechnology

Article	Citations
Editorial Board	281
Editorial Board	226
Corrigendum to “Methylotrophs: from C1 compounds to food” [Curr Opin Biotechnol 75 (2022) 102685]	135
Tumor lipid metabolism: a mechanistic link between diet and cancer progression	131
Anaerobic microbial methanol utilization as a one-carbon feedstock	127
How much could improving photosynthesis increase crop yields? A call for systems-level perspectives to guide engineering strategies	123
Bioelectrosynthesis systems	122
Cell-free technologies for biopharmaceutical research and production	116
Creating value from purple phototrophic bacteria via single-cell protein production	107
Recent progress in the synthesis of advanced biofuel and bioproducts	107
Systems biology-based analysis of cell-free systems	106
The osteo-angiogenic signaling crosstalk for bone regeneration: harmony out of complexity	100
Synthetic biology advances towards a bio-based society in the era of artificial intelligence	95
Applications of artificial intelligence to enzyme and pathway design for metabolic engineering	95
The journey of a lifetime — development of Pfizer’s COVID-19 vaccine	93
Engineered living bioassemblies for biomedical and functional material applications	82
Lighting the way: recent developments and applications in molecular optogenetics	81
Engineered T cells and macrophages: two arms to seize solid tumors	78
Innovations and trends in antibody repertoire analysis	76
A molecular assessment of the practical potential of DNA-based computation	72
Editorial Board	70
Leveraging rAAV bioprocess understanding and next generation bioanalytics development	66
Editorial Board	65
Coupling chemistry and biology for the synthesis of advanced bioproducts	64
Whole-plant phenotypic engineering: moving beyond ratios for multi-objective optimization of nutrient use efficiency	62

Single-cell analysis opens a goldmine for plant functional studies	60
Molecular methods for high-throughput, multiplexed, and automated genome editing in prokaryotes and eukaryotes	57
Recent advances, opportunities and challenges in cybergenetic identification and control of biomolecular networks	57
Microfluidics meets cell-free systems: from molecular engineering to synthetic cells	57
Genetically encoded elastin-like polypeptide nanoparticles for drug delivery	56
Deep learning in regulatory genomics: from identification to design	56
Computational tools and resources for designing new pathways to small molecules	55
Emerging technologies for genetic control systems in cellular therapies	55
The plant microbiota: composition, functions, and engineering	55
Engineering of the genetic code	55
Using genome and transcriptome analysis to elucidate biosynthetic pathways	52
Emerging trends in production of plant natural products and new-to-nature biopharmaceuticals in yeast	52
Machine learning to navigate fitness landscapes for protein engineering	51
Strategies for engineering domesticated and undomesticated human microbes	51
Biocatalytic cascade transformations for the synthesis of C-nucleosides and N-nucleoside analogs	50
2-hydroxyglutarate rides the cancer-immunity cycle	49
Dietary microalgae on poultry meat and eggs: explained versus unexplained effects	49
Multifaceted metabolic role of infections in the tumor microenvironment	49
Perspectives for self-driving labs in synthetic biology	49
Building trust in automated experimentation: uncertainty quantification in the era of high-throughput biolabs	48
Mass spectrometry imaging methods for visualizing tumor heterogeneity	48
Harnessing the potential of microbial methane utilization for chasing sustainability	48
Plant synthetic biology as a tool to help eliminate hidden hunger	48
Matching diverse feedstocks to conversion processes for the future bioeconomy	48
Tissue engineering in the agri-food industry: current status, socio-economic overview and regulatory compliance	48
Editorial overview: Biotechnological insights of marine and terrestrial microbiome	47
Editorial Board	47
Toolboxes for plant systems biology research	46
Reducing crop losses by gene-editing control of organ developmental physiology	45
Low-cost, point-of-care biomarker quantification	44
Editorial overview: Pioneering innovations in food biotechnology	44
Corrigendum to: “Design, construction, and application of noncanonical redox cofactor infrastructures” [Curr Opin Biotechnol 84 (2023) 103019]	44
Synthetic biology approaches for dynamic CHO cell engineering	44
Advancing in vivo reprogramming with synthetic biology	44
Single-cell omics analysis with genome-scale metabolic modeling	43
Pathway engineering for the biosynthesis of psychedelics	43
Understanding atmospheric intercontinental dispersal of harmful microorganisms	43
Editorial overview: Emerging routes to sustainable energy capture and conversion into value-added products	43
The potential of amoeba-based processes for natural product syntheses	42
Biochemical production with microbial bioelectrochemical systems	41
Metabolic and cellular engineering for the production of natural products	40
Molecules to medicine: advances in metabolomics for natural product drug discovery	40
Sourcing DNA parts for synthetic biology applications in plants	40
Synthetic apomixis: the beginning of a new era	40
Editorial Board	40
Editorial overview: Nanobiotechnology for immunoengineering	40
Impact of anthropogenic contamination on glacier surface biota	40
Editorial Board	40
Understanding and harnessing the complexity of interspecies interactions in acetogenic mixotrophic co-cultures	39
Synthetic mRNA – emerging new class of drug for tissue regeneration	39

Operation at thermophilic temperatures: an underestimated asset for gas fermentation processes	39
The aging tumor metabolic microenvironment	39
Complexity of subcellular metabolism: strategies for compartment-specific profiling	39
Engineered methane biocatalysis: strategies to assimilate methane for chemical production	39
Strategies and opportunities for engineering antifungal peptides for therapeutic applications	38
Targeting ripening regulators to develop fruit with high quality and extended shelf life	38
Matchmaking at the cell surface using bispecifics to put cells on their best behavior	38
Next-generation biological vector platforms for in vivo delivery of genome editing agents	38
Programmable synthetic biology tools for developing microbial cell factories	37
Synthetic fuels: what are they and where do they come from?	37
What’s new in single-cell proteomics	37
Antigen-specific nanomedicines for the treatment of autoimmune disease: target cell types, mechanisms and outcomes	37
Potential use of microbial engineering in single-cell protein production	36
Extracellular vesicles as therapeutics for inflammation and infection	36
Bridging the gender gap in autoimmunity with T-cell–targeted biomaterials	35
Editorial Board	35
Beyond vancomycin: recent advances in the modification, reengineering, production and discovery of improved glycopeptide antibiotics to tackle multidrug-resistant bacteria	34
Strategies for uncovering stable isotope tracing patterns between cell populations	34
De novo domestication: retrace the history of agriculture to design future crops	34
Challenges and future perspectives for high-throughput chimeric antigen receptor T cell discovery	34
Optimizing the value of bioinks and robotics to advance in vivo bioprinting	34
Editorial Board	34
Engineering bacterial warriors: harnessing microbes to modulate animal physiology	34
Biotechnology approaches for natural product discovery, engineering, and production based on Burkholderia bacteria	33
Inhalable mRNA vaccines for respiratory diseases: a roadmap	32
Machine learning for predicting phenotype from genotype and environment	32
Analytical tools for unravelling the metabolism of gas-fermenting Clostridia	32
Recent innovations in cannabinoid chemistry, biology, and biosynthesis	32
Can digital twin efforts shape microorganism-based alternative food?	31
Editorial overview: Tissue, cell, and pathway engineering	31
Two in one: the emerging concept of bifunctional antibodies	31
Quantitative and analytical tools to analyze the spatiotemporal population dynamics of microbial consortia	31
Microbiological food safety considerations in shelf-life extension of fresh fruits and vegetables	31
In situ characterization of the tumor microenvironment	31
Biologics-based degraders — an expanding toolkit for targeted-protein degradation	31
Cell-free synthesis of industrial chemicals and biofuels from carbon feedstocks	30
Achieving net zero CO2 emission in the biobased production of reduced platform chemicals using defined co-feeding of methanol	30
Corrigendum to “Unraveling the mechanobiology of immune cells” [Curr Opin Biotechnol 66 (2020) 236-245]	30
Editorial Board	30
An integrated eco-evolutionary framework to predict population-level responses of climate-sensitive pathogens	30
Senescent cells in tissue engineering	29
Genetic and process engineering for polyhydroxyalkanoate production from pre- and post-consumer food waste	29
Clustered regularly interspaced short palindromic repeats tools for plant metabolic engineering: achievements and perspectives	29
Advances in engineering substrate scope of Pseudomonas cell factories	29
Engineering plant–microbe communication for plant nutrient use efficiency	29
Mycotoxin risks are lower in biotech corn	29
Searching for the optimal microbial factory: high-throughput biosensors and analytical techniques for screening small molecules	29
Progress and challenges in the translation of cancer nanomedicines	29
Engineering next-generation chimeric antigen receptor-T cells: recent breakthroughs and remaining challenges in design and screening of novel chimeric antigen receptor variants	29
Advances in engineering and optimization of transcription factor-based biosensors for plug-and-play small molecule detection	28
Division of labor for substrate utilization in natural and synthetic microbial communities	28
Recent trends in the modification of polyphenolic compounds using hydroxylation and glycosylation	28
Decoding dissolved information: environmental DNA sequencing at global scale to monitor a changing ocean	28
Sustainability in food-waste reduction biotechnology: a critical review	28
Path to zero emission of nitrous oxide in sewage treatment: is nitrification controllable or avoidable?	27
Recent advances in microbial synthesis of polyphenols	27
General framework for enzyme-photo-coupled catalytic system toward carbon dioxide conversion	27
Understanding methanol metabolism through systems biology: advances and future perspectives	26
Recent advances in microbial production of rare sugars and steviols	26
Force in numbers: high-throughput screening approaches to unlock microbial transport	26
Proteomics insights into the fungal-mediated bioremediation of environmental contaminants	26
Integrating bioprinting and optogenetic technologies for precision plant tissue engineering	26
Computational models in systems biology: standards, dissemination, and best practices	26
Eubacterium limosum as a biocatalyst for sustainable methanol bioconversion	26
Carbon recycling with synthetic CO2 fixation pathways	26
Advances in engineering algae for biofuel production	26
Cellobiose dehydrogenase in biofuel cells	25
Cell-free enzyme cascades — application and transition from development to industrial implementation	25
Quantifying nanoparticle delivery: challenges, tools, and advances	25
Combining enzyme and metabolic engineering for microbial supply of therapeutic phytochemicals	25
Engineering organoids as cerebral disease models	25
Engineering bacteria for cancer immunotherapy	25
Continuous biomanufacturing with microbes — upstream progresses and challenges	24
Engineering microbial consortia with rationally designed cellular interactions	24
Getting better all the time — recent progress in the development of CRISPR/Cas-based tools for plant genome engineering	24
Anaerobic microbial core for municipal wastewater treatment — the sustainable platform for resource recovery	24
Approaches for a more microbiologically and chemically safe dried fruit supply chain	24
Pleiotropy, a feature or a bug? Toward co-ordinating plant growth, development, and environmental responses through engineering plant hormone signaling	24
Biomolecular feedback controllers: from theory to applications	24
Building mutational bridges between carbohydrate-active enzymes	24

Cytochromes P450 in the biocatalytic valorization of lignin	24
Designed dietary fibers: engineering carbohydrate structure for precision modulation of the human gut microbiome	24
Machine learning applications to improve flavor and nutritional content of horticultural crops through breeding and genetics	23
Architectures of emerging biofoundry platforms for synthetic biology	23
Recent advances in the biological depolymerization and upcycling of polyethylene terephthalate	23
Time to integrate biotechnological approaches into fish gut microbiome research	23
Drugging the microbiome and bacterial live biotherapeutic consortium production	23
Optogenetics in medicine: innovations and therapeutic applications	23
Resolving misconceptions and constraints in growth-coupled bioproduction	23
Editorial overview: Phosphate Special Issue	23
SgRNA engineering for improved genome editing and expanded functional assays	23
Antimicrobial polymeric biomaterials based on synthetic, nanotechnology, and biotechnological approaches	23
The double life of CRISPR–Cas13	23