Current Opinion in Biotechnology

Article	Citations
Editorial Board	159
Editorial Board	148
The osteo-angiogenic signaling crosstalk for bone regeneration: harmony out of complexity	134
Corrigendum to “Methylotrophs: from C1 compounds to food” [Curr Opin Biotechnol 75 (2022) 102685]	110
The journey of a lifetime — development of Pfizer’s COVID-19 vaccine	109
Creating value from purple phototrophic bacteria via single-cell protein production	105
Tumor lipid metabolism: a mechanistic link between diet and cancer progression	96
Synthetic biology advances towards a bio-based society in the era of artificial intelligence	93
Systems biology-based analysis of cell-free systems	91
Recent progress in the synthesis of advanced biofuel and bioproducts	91
Anaerobic microbial methanol utilization as a one-carbon feedstock	87
Bacterial degradation of emerging aromatic pollutants and integrated strategies for sustainable healthy agro-ecosystem	78
Cell-free technologies for biopharmaceutical research and production	75
How much could improving photosynthesis increase crop yields? A call for systems-level perspectives to guide engineering strategies	75
Deep learning in regulatory genomics: from identification to design	69
A molecular assessment of the practical potential of DNA-based computation	68
Engineered T cells and macrophages: two arms to seize solid tumors	67
Coupling chemistry and biology for the synthesis of advanced bioproducts	67
Emerging technologies for genetic control systems in cellular therapies	66
Editorial Board	65
Recent advances, opportunities and challenges in cybergenetic identification and control of biomolecular networks	65
Editorial Board	63
Engineered living bioassemblies for biomedical and functional material applications	62
Lighting the way: recent developments and applications in molecular optogenetics	59
Innovations and trends in antibody repertoire analysis	59

Whole-plant phenotypic engineering: moving beyond ratios for multi-objective optimization of nutrient use efficiency	57
Expanding the catalytic repertoire of C–C bond–forming pyridoxal 5′-phosphate-dependent enzymes for noncanonical amino acid formation	57
Microfluidics meets cell-free systems: from molecular engineering to synthetic cells	57
Single-cell analysis opens a goldmine for plant functional studies	57
Strategies and challenges for synthetic apomixis	56
Multifaceted metabolic role of infections in the tumor microenvironment	56
Molecular methods for high-throughput, multiplexed, and automated genome editing in prokaryotes and eukaryotes	56
Dietary microalgae on poultry meat and eggs: explained versus unexplained effects	55
Computational tools and resources for designing new pathways to small molecules	55
Photoprotective-based strategies to enhance crop yield under fluctuating light conditions	54
Strategies for engineering domesticated and undomesticated human microbes	53
Deciphering the guanidine code: from core metabolism to biosynthesis of its derivatives	53
Biocatalytic cascade transformations for the synthesis of C-nucleosides and N-nucleoside analogs	51
Using genome and transcriptome analysis to elucidate biosynthetic pathways	51
Engineering of the genetic code	51
Emerging trends in production of plant natural products and new-to-nature biopharmaceuticals in yeast	50
Mass spectrometry imaging methods for visualizing tumor heterogeneity	49
2-hydroxyglutarate rides the cancer-immunity cycle	49
Machine learning to navigate fitness landscapes for protein engineering	48
Perspectives for self-driving labs in synthetic biology	48
Tissue engineering in the agri-food industry: current status, socio-economic overview and regulatory compliance	48
Editorial Board	47
Harnessing the potential of microbial methane utilization for chasing sustainability	45
Editorial Board	45
Toolboxes for plant systems biology research	45
Matching diverse feedstocks to conversion processes for the future bioeconomy	45
Advancing in vivo reprogramming with synthetic biology	45
Plant synthetic biology as a tool to help eliminate hidden hunger	44
Building trust in automated experimentation: uncertainty quantification in the era of high-throughput biolabs	43
Reducing crop losses by gene-editing control of organ developmental physiology	43
Corrigendum to: “Design, construction, and application of noncanonical redox cofactor infrastructures” [Curr Opin Biotechnol 84 (2023) 103019]	42
Synthetic biology approaches for dynamic CHO cell engineering	42
Low-cost, point-of-care biomarker quantification	41
Editorial overview: Pioneering innovations in food biotechnology	40
Impact of anthropogenic contamination on glacier surface biota	40
Understanding atmospheric intercontinental dispersal of harmful microorganisms	40
The potential of amoeba-based processes for natural product syntheses	39
Plant microbiome regulation for sustainable agriculture	38
Metabolic and cellular engineering for the production of natural products	38
Pathway engineering for the biosynthesis of psychedelics	38
Sourcing DNA parts for synthetic biology applications in plants	38
Synthetic apomixis: the beginning of a new era	37
Single-cell omics analysis with genome-scale metabolic modeling	37
Biochemical production with microbial bioelectrochemical systems	37
Molecules to medicine: advances in metabolomics for natural product drug discovery	37
Editorial overview: Nanobiotechnology for immunoengineering	36
PRRs and NLRs sans frontières: advances and challenges in transfer of immune receptors between plant species	36
Editorial Board	36
Complexity of subcellular metabolism: strategies for compartment-specific profiling	35
What’s new in single-cell proteomics	35

Operation at thermophilic temperatures: an underestimated asset for gas fermentation processes	35
Extracellular vesicles as therapeutics for inflammation and infection	35
Matchmaking at the cell surface using bispecifics to put cells on their best behavior	34
Strategies and opportunities for engineering antifungal peptides for therapeutic applications	34
Potential use of microbial engineering in single-cell protein production	33
Synthetic fuels: what are they and where do they come from?	33
Next-generation biological vector platforms for in vivo delivery of genome editing agents	33
The aging tumor metabolic microenvironment	32
Engineered methane biocatalysis: strategies to assimilate methane for chemical production	32
Targeting ripening regulators to develop fruit with high quality and extended shelf life	32
Understanding and harnessing the complexity of interspecies interactions in acetogenic mixotrophic co-cultures	32
Biotechnology approaches for natural product discovery, engineering, and production based on Burkholderia bacteria	31
Bridging the gender gap in autoimmunity with T-cell–targeted biomaterials	31
Editorial Board	31
Programmable synthetic biology tools for developing microbial cell factories	31
De novo domestication: retrace the history of agriculture to design future crops	30
Engineering bacterial warriors: harnessing microbes to modulate animal physiology	30
Recent innovations in cannabinoid chemistry, biology, and biosynthesis	30
Optimizing the value of bioinks and robotics to advance in vivo bioprinting	30
Editorial Board	30
Engineering whole-cell catalysts to use plastic waste as a feedstock	30
Microbiological food safety considerations in shelf-life extension of fresh fruits and vegetables	30
Analytical tools for unravelling the metabolism of gas-fermenting Clostridia	30
Can digital twin efforts shape microorganism-based alternative food?	29
Recent advances in microbial lignin degradation and upcycling of lignin-derived aromatic compounds	29
Challenges and future perspectives for high-throughput chimeric antigen receptor T cell discovery	29
Beyond vancomycin: recent advances in the modification, reengineering, production and discovery of improved glycopeptide antibiotics to tackle multidrug-resistant bacteria	29
Clustered regularly interspaced short palindromic repeats tools for plant metabolic engineering: achievements and perspectives	28
Strategies for uncovering stable isotope tracing patterns between cell populations	28
Progress and challenges in the translation of cancer nanomedicines	28
Machine learning for predicting phenotype from genotype and environment	28
Recent trends in the modification of polyphenolic compounds using hydroxylation and glycosylation	28
Design of DNA strand displacement reactions	27
An integrated eco-evolutionary framework to predict population-level responses of climate-sensitive pathogens	27
Quantitative and analytical tools to analyze the spatiotemporal population dynamics of microbial consortia	27
Editorial Board	27
In situ characterization of the tumor microenvironment	27
Editorial overview: Tissue, cell, and pathway engineering	27
Achieving net zero CO2 emission in the biobased production of reduced platform chemicals using defined co-feeding of methanol	27
Division of labor for substrate utilization in natural and synthetic microbial communities	27
Mycotoxin risks are lower in biotech corn	27
Decoding dissolved information: environmental DNA sequencing at global scale to monitor a changing ocean	27
Senescent cells in tissue engineering	27
Genetic and process engineering for polyhydroxyalkanoate production from pre- and post-consumer food waste	26
Advances in engineering substrate scope of Pseudomonas cell factories	26
Advances in engineering and optimization of transcription factor-based biosensors for plug-and-play small molecule detection	26
Biologics-based degraders — an expanding toolkit for targeted-protein degradation	26
Engineering plant–microbe communication for plant nutrient use efficiency	26
Sustainability in food-waste reduction biotechnology: a critical review	26
Engineering next-generation chimeric antigen receptor-T cells: recent breakthroughs and remaining challenges in design and screening of novel chimeric antigen receptor variants	25
Two in one: the emerging concept of bifunctional antibodies	25
Integrating bioprinting and optogenetic technologies for precision plant tissue engineering	25
Searching for the optimal microbial factory: high-throughput biosensors and analytical techniques for screening small molecules	25
Path to zero emission of nitrous oxide in sewage treatment: is nitrification controllable or avoidable?	25
Recent advances in microbial production of rare sugars and steviols	25
Eubacterium limosum as a biocatalyst for sustainable methanol bioconversion	25
Recent advances in microbial synthesis of polyphenols	24
Proteomics insights into the fungal-mediated bioremediation of environmental contaminants	24
Engineering bacteria for cancer immunotherapy	24
Advances in artificial biosynthesis of bioactive plant natural products	24
Advances in engineering algae for biofuel production	24
Computational models in systems biology: standards, dissemination, and best practices	24
Understanding methanol metabolism through systems biology: advances and future perspectives	23
Reprogramming immunity: TAL effector-informed genome editing in rice and other crops	23
Designed dietary fibers: engineering carbohydrate structure for precision modulation of the human gut microbiome	23
Drugging the microbiome and bacterial live biotherapeutic consortium production	23
Carbon recycling with synthetic CO2 fixation pathways	23
Getting better all the time — recent progress in the development of CRISPR/Cas-based tools for plant genome engineering	23
Building mutational bridges between carbohydrate-active enzymes	23
Architectures of emerging biofoundry platforms for synthetic biology	22
Cell-free enzyme cascades — application and transition from development to industrial implementation	22
Approaches for a more microbiologically and chemically safe dried fruit supply chain	22
Combining enzyme and metabolic engineering for microbial supply of therapeutic phytochemicals	22
Pleiotropy, a feature or a bug? Toward co-ordinating plant growth, development, and environmental responses through engineering plant hormone signaling	22
Shaping Aspergillus niger into a next-generation cell factory for L-malic acid	22
Quantifying nanoparticle delivery: challenges, tools, and advances	22
Machine learning applications to improve flavor and nutritional content of horticultural crops through breeding and genetics	22
Biomolecular feedback controllers: from theory to applications	22
Engineering organoids as cerebral disease models	22
Cell-free biosensors: where have we been and where do we need to go?	22

Deep learning and generative artificial intelligence methods in enzyme and cell engineering	22
Engineering microbial consortia with rationally designed cellular interactions	22