Current Opinion in Genetics & Development

Article	Citations
Epithelial–immune crosstalk in health and disease	72
Editorial Board	50
Editorial Board	47
Editorial Board	47
Why is measuring and predicting fitness under genomic conflict so hard?	46
DNA end resection during homologous recombination	39
Adipose tissue endothelial cells: insights into their heterogeneity and functional diversity	39
Editorial overview: Conflicts, conflicts everywhere	39
A critical role for X-chromosome architecture in mammalian X-chromosome dosage compensation	39
Tile by tile: capturing the evolutionary mosaic of human conditions	36
Break-induced replication mechanisms in yeast and mammals	35
The X chromosome in C. elegans sex determination and dosage compensation	33
Integrative approaches to study enhancer–promoter communication	33
Loops, crosstalk, and compartmentalization: it takes many layers to regulate DNA methylation	32
R-loops in neurodegeneration	32
Editorial Board	29
In vitro models of pre- and post-gastrulation embryonic development	29
Control of cell fate upon transcription factor–driven cardiac reprogramming	28
Therapeutic strategies to target the epitranscriptomic machinery	28
Genetic clues to reprogramming power and formation of mouse oocyte	28
Interplay between N-adenosine RNA methylation and mRNA splicing	27
Mitochondrial metabolism and the continuing search for ultimate regulators of developmental rate	26
NAT10 and cytidine acetylation in mRNA: intersecting paths in development and disease	26
Toward the dissection of hematopoietic stem cell fates and their determinants	25
Single-cell genomic profiling to study regeneration	25

High-throughput approaches to functional characterization of genetic variation in yeast	25
Reprogramming lineage identity through cell–cell fusion	25
Epigenetic memory in reprogramming	25
Recombination-mediated genome rearrangements	25
If you please, draw me a neuron — linking evolutionary tinkering with human neuron evolution	24
Editorial Board	24
Using human pluripotent stem cells to dissect trophoblast development	24
Cell–cell interactions between transplanted retinal organoid cells and recipient tissues	24
Something old, something new, something borrowed, something red: the origin of ecologically relevant novelties in Hemiptera	24
Molecular genetics of pulmonary hypertension in children	23
Stem-cell-based human and mouse embryo models	23
Better together: how cooperativity influences transcriptional bursting	23
Adipose tissue-derived lipokines in metabolism	23
Timers, variability, and body-wide coordination: C. elegans as a model system for whole-animal developmental timing	23
How strand exchange protein function benefits from ATP hydrolysis	22
Structural variation in humans and our primate kin in the era of telomere-to-telomere genomes and pangenomics	22
Transposon waves at the water-to-land transition	22
Dynamic microenvironments shape nuclear organization and gene expression	21
Editorial overview: Drivers, droplets, and deeds of nuclear genome organization	20
Editorial overview: Recombination — the ends justify the means	20
Editorial overview: Multiscale regulation of genome folding in space, time, and across the tree of life	20
Multi-organelle-mediated mRNA localization in neurons and links to disease	19
Nuclear remodeling during cell fate transitions	19
Human 8-cell embryo-like cells from pluripotent stem cells	19
Modifying gastruloids to dissect mechanisms of tissue-specific induction	19
Recipes and ingredients for deep learning models of 3D genome folding	19
Enhancers on the edge — how the nuclear envelope controls gene regulatory elements	19
Eco-evo-devo advances with butterfly eyespots	18
Intestinal epithelial organoids: regeneration and maintenance of the intestinal epithelium	18
Digesting the mechanobiology of the intestinal epithelium	17
Editorial overview: Peering into our history through a genetic lens: How advances in genetics are changing our understanding of human evolution	17
Epigenetic priming in the male germline	17
Nucleosomes in mammalian sperm: conveying paternal epigenetic inheritance or subject to reprogramming between generations?	17
Meiotic drive of noncentromeric loci in mammalian meiosis II eggs	17
RNA interference therapeutics for cardiac regeneration	16
Shaping inheritance: how distinct reproductive strategies influence DNA methylation memory in plants	16
Inheritance of epigenetic transcriptional memory	16
What are tethering elements?	16
Cell identity conversion in liver regeneration after injury	16
Maternal genetic factors in the development of congenital heart defects	16
Evolution of 3D chromatin organization at different scales	16
Cancer-associated chromatin variants uncover the oncogenic role of transposable elements	16
Chromatin architecture reorganization during somatic cell reprogramming	15
Approaches to probe and perturb long noncoding RNA functions in diseases	15
DNA helicases in homologous recombination repair	15
Editorial Board	15
Editorial overview: Epigenetic inheritance: A shortcut to environmental adaptation?	15
Trends and variation in vertebrate patterns as outcomes of self-organization	14
Discrete roles for Rad54 and Rdh54 during homologous recombination	14
Advances in skeletal genomics research across tissues and cells	14

Songbird germline-restricted chromosome as a potential arena of genetic conflicts	14
A complex gene regulatory architecture underlies the development and evolution of cuticle morphology in Drosophila	14
Rewiring cancer: 3D genome determinants of cancer hallmarks	13
Editorial Board	13
Deciphering microglia phenotypes in health and disease	13
Editorial overview: Regaining architecture and cell cross-talk upon regeneration	13
Cellular plasticity in the neural crest and cancer	13
Transposable elements in early human embryo development and embryo models	13
A new era of understanding in vivo metabolic flux in thermogenic adipocytes	13
Editorial overview: Epitranscriptomics: Exploring a new frontier in health and disease	13
Amending the injured heart by in vivo reprogramming	12
Cellular and developmental basis of avian structural coloration	12
Editorial overview: The genome in space–time	12
Cellular identity through the lens of direct lineage reprogramming	12
Evolution and molecular bases of reproductive isolation	12
Alterations in transcriptional networks in cancer: the role of noncoding somatic driver mutations	12
Correlation between protein abundance and sequence conservation: what do recent experiments say?	12
Toward a comprehensive view of gene architecture during transcription	12
Brain organoids: the quest to decipher human-specific features of brain development	12
Evolution of sexual development and sexual dimorphism in insects	12
Adipose tissue lipid metabolism: lipolysis	12
Regional patterning and regulation of melanin pigmentation in insects	12
Architecture of RNA–RNA interactions	12
Principles of genome activation in the early embryo	12
The stem cell zoo for comparative studies of developmental tempo	12
Challenges and potential solutions for studying the genetic and phenotypic architecture of adaptation in microbes	12
Epistasis and evolutionary dependencies in human cancers	11
Editorial Board	11
Genome folding dynamics during the M-to-G1-phase transition	11
Exploring conditional gene essentiality through systems genetics approaches in yeast	11
The role of loop extrusion in enhancer-mediated gene activation	11
Editorial Board	11
Mechanism of mitotic recombination: insights from C. elegans	11
Editorial Board	11
Microbial experimental evolution in a massively multiplexed and high-throughput era	11
Alternative splicing in addiction	11
Bridging spatial and temporal scales of developmental gene regulation	11
Phase separation and inheritance of repressive chromatin domains	11
When 3D genome changes cause disease: the impact of structural variations in congenital disease and cancer	11
Transcriptional regulation of T cell metabolism and metabolic control of T cell gene expression	11
An extending ATR–CHK1 circuitry: the replication stress response and beyond	11
Recent developments in adipose tissue-secreted factors and their target organs	11
Oncogenic fusion proteins and their role in three-dimensional chromatin structure, phase separation, and cancer	11
In vitro models of human hypoblast and mouse primitive endoderm	11
Dissecting nephron morphogenesis using kidney organoids from human pluripotent stem cells	11
3D chromosomal architecture in germinal center B cells and its alterations in lymphomagenesis	11
Proliferation and dissemination of killer meiotic drive loci	11
Topical section: embryonic models (2023) for Current Opinion in Genetics & Development	10
In search of conserved principles of planar cell polarization	10
The role of tissue maturity and mechanical state in controlling cell extrusion	10
Chromosome organization in 4D: insights from C. elegans development	10
Seasonal plasticity: how do butterfly wing pattern traits evolve environmental responsiveness?	10
Polycomb complexes in MLL–AF9-related leukemias	10
The role of SAF-A/hnRNP U in regulating chromatin structure	10
Reconstitution of reproductive organ system that produces functional oocytes	10
Paternal genome elimination: patterns and mechanisms of drive and silencing	10
Quantitative mapping of the mammalian epitranscriptome	9
Pigmentation and color pattern diversity in Odonata	9
Jack of all trades versus master of one: how generalist versus specialist strategies of transposable elements relate to their horizontal transfer between lineages	9
The power of proximity: mechanisms and biological roles of transvection	9
Hijacked enhancer–promoter and silencer–promoter loops in cancer	9
Cellular diversity and developmental hierarchy in the planarian nervous system	9
To splice or not to splice: pseudoexons in neurological disease and opportunities for intervention	9
Timing mechanisms: insights from comparative neural differentiation systems	9
Can we stop one heart from breaking: triumphs and challenges in cardiac reprogramming	9
Prospects for precision genetic medicine in congenital heart disease	9
R-loop homeostasis in genome dynamics, gene expression and development	9
The genetic landscape of cardiovascular left–right patterning defects	9
Decoding N6-methyladenosine’s dynamic role in stem cell fate and early embryo development: insights into RNA–chromatin interactions	9
The metabolic baton: conducting the dance of N6-methyladenosine writing and erasing	9
Principles of long-range gene regulation	9
Recent advances in stem cell-based blastocyst models	9
The transcription factor code in iPSC reprogramming	9
Ex situ-armus: experimental models for combating respiratory dysfunction	8
Chromosomal instability as a source of genomic plasticity	8
Female meiotic drive in plants: mechanisms and dynamics	8
Clinical Perspectives in Epitranscriptomics	8
Pediatric CNS cancer genomics and immunogenomics	8
Making region-specific integumentary organs in birds: evolution and modifications	8
Distinct fibroblasts in scars and regeneration	8

Do sex-linked male meiotic drivers contribute to intrinsic hybrid incompatibilities? Recent empirical studies from flies and rodents	7
Reprogramming cellular identity during intestinal regeneration	7
Recent insights into the evolution of mutation rates in yeast	7
Interplay of transposable elements and ageing: epigenetic regulation and potential epitranscriptomic influence	7
Recent insights into the in vitro culture systems for mammalian embryos	7
Non-model systems in mammalian forelimb evo-devo	7
Modification of the RNA methylome in neurodevelopmental disorders	7
Corneal regeneration: insights in epithelial stem cell heterogeneity and dynamics	7
Overcoming muscle stem cell aging	7
Circuit integration by transplanted human neurons	7
Evolutionary neurogenomics at single-cell resolution	7
Pancreatic cell fate specification: insights into developmental mechanisms and their application for lineage reprogramming	7
Experimental evolution of drug resistance in human fungal pathogens	7
The WRN helicase: resolving a new target in microsatellite unstable cancers	7
Vascular and immune interactions in islets transplantation and 3D islet models	7
Linking mitochondria metabolism, developmental timing, and human brain evolution	7
Pluripotent stem cell–derived mesenchymal stem cells for therapeutic applications, developmental study, and cancer research	7
Mechanisms of regulatory evolution in yeast	7
Editorial Board	7
Temporal patterning of the vertebrate developing neural tube	7
Epigenetic dynamics during germline development: insights from Drosophila and C. elegans	7
Recombination-dependent replication: new perspectives from site-specific fork barriers	6
Insights into multilevel spatial regulation within the root stem cell niche	6
Xenotransplantation — a shortcut to construct tissue complexity in organoids	6
Metabolic regulation of cardiac regeneration: roles of hypoxia, energy homeostasis, and mitochondrial dynamics	6
Concepts, mechanisms and implications of long-term epigenetic inheritance	6
Extending the spectrum in aortopathy: stenosis to aneurysm	6
The evolution and genetics of lepidopteran egg and caterpillar coloration	6
Deciphering the role of structural variation in human evolution: a functional perspective	6
Advancements in inner ear development, regeneration, and repair through otic organoids	6
Factors that determine cell type–specific CTCF binding in health and disease	6
Transgenerational epigenetic control of constitutive heterochromatin, transposons, and centromeres	6
Therapeutic index of targeting select chromatin complexes in human cancer patients	6
Extracellular vesicles for remote brain repair	6
A new era in neuromuscular junction research: current advances in self-organized and assembled in vitro models	6
Engineering immune organoids to regenerate host immune system	6
RAD51 paralog function in replicative DNA damage and tolerance	6
Network models of chromatin structure	6
The ribonucleoprotein network of the nucleus: a historical perspective	6
Epithelial folding determines the final shape of beetle horns	6
The ever-growing world of gastruloids: autogenous models of mammalian embryogenesis	6
Narrative engineering of the liver	6
Early central nervous system development and neuron regeneration	6
When and why are mitochondria paternally inherited?	6
Multi-scale dynamics of heterochromatin repair	5
Editorial Board	5
Decoding the role of tRNA modifications in cancer progression	5
Editorial overview: Early embryonic development models: back to the beginning	5
Somatic mutation burden in relation to aging and functional life span: implications for cellular reprogramming and rejuvenation	5
Rethinking chromatin accessibility: from compaction to dynamic interactions	5
Editorial overview: New insights into epithelial dynamics: From tissue homeostasis to morphogenesis	5
Editorial overview: Fat tissue in focus: Assembled deeply insightful perspectives on state-of-the-art explorations	5
Spatial orchestration of the genome: topological reorganisation during X-chromosome inactivation	5
A finger on the pulse of regeneration: insights into the cellular mechanisms of adult digit tip regeneration	5
A lifelong duty: how Xist maintains the inactive X chromosome	5
Safeguarding the epigenome through the cell cycle: a multitasking game	5
Human trophoblast stem cell-state acquisition from pluripotent stem cells and somatic cells	5
Interplay between Sae2 and Rif2 in the regulation of Mre11-Rad50 activities at DNA ends	5
Recent advances in RNA-based therapeutics for neurodevelopmental disorders	5
Molecular mechanisms of the specialization of human synapses in the neocortex	5
Adipocyte plasticity in tissue regeneration, repair, and disease	5
Plasticity of muscle stem cells in homeostasis and aging	5
Genomic snowflakes: how the uniqueness of DNA folding allows us to smell the chemical universe	5