Current Opinion in Genetics & Development

Article	Citations
Editorial Board	50
Editorial Board	49
Editorial Board	48
Why is measuring and predicting fitness under genomic conflict so hard?	42
Editorial overview: Conflicts, conflicts everywhere	41
DNA end resection during homologous recombination	40
Tile by tile: capturing the evolutionary mosaic of human conditions	39
Loops, crosstalk, and compartmentalization: it takes many layers to regulate DNA methylation	37
Epithelial–immune crosstalk in health and disease	36
Break-induced replication mechanisms in yeast and mammals	34
Integrative approaches to study enhancer–promoter communication	33
A critical role for X-chromosome architecture in mammalian X-chromosome dosage compensation	32
R-loops in neurodegeneration	31
The X chromosome in C. elegans sex determination and dosage compensation	31
In vitro models of pre- and post-gastrulation embryonic development	29
Editorial Board	29
Adipose tissue endothelial cells: insights into their heterogeneity and functional diversity	29
Therapeutic strategies to target the epitranscriptomic machinery	28
Mitochondrial metabolism and the continuing search for ultimate regulators of developmental rate	28
Interplay between N-adenosine RNA methylation and mRNA splicing	27
Toward the dissection of hematopoietic stem cell fates and their determinants	27
Control of cell fate upon transcription factor–driven cardiac reprogramming	27
NAT10 and cytidine acetylation in mRNA: intersecting paths in development and disease	26
Genetic clues to reprogramming power and formation of mouse oocyte	26
Epigenetic memory in reprogramming	26

Single-cell genomic profiling to study regeneration	25
High-throughput approaches to functional characterization of genetic variation in yeast	25
If you please, draw me a neuron — linking evolutionary tinkering with human neuron evolution	25
Using human pluripotent stem cells to dissect trophoblast development	25
Stem-cell-based human and mouse embryo models	24
Cell–cell interactions between transplanted retinal organoid cells and recipient tissues	24
Molecular genetics of pulmonary hypertension in children	24
Recombination-mediated genome rearrangements	24
Better together: how cooperativity influences transcriptional bursting	24
Reprogramming lineage identity through cell–cell fusion	24
How strand exchange protein function benefits from ATP hydrolysis	23
Adipose tissue-derived lipokines in metabolism	23
Transposon waves at the water-to-land transition	23
Timers, variability, and body-wide coordination: C. elegans as a model system for whole-animal developmental timing	22
Structural variation in humans and our primate kin in the era of telomere-to-telomere genomes and pangenomics	21
Editorial overview: Recombination — the ends justify the means	20
Dynamic microenvironments shape nuclear organization and gene expression	20
Editorial overview: Drivers, droplets, and deeds of nuclear genome organization	20
Modifying gastruloids to dissect mechanisms of tissue-specific induction	19
Editorial overview: Multiscale regulation of genome folding in space, time, and across the tree of life	19
Digesting the mechanobiology of the intestinal epithelium	19
Human 8-cell embryo-like cells from pluripotent stem cells	18
Recipes and ingredients for deep learning models of 3D genome folding	18
Nuclear remodeling during cell fate transitions	18
Enhancers on the edge — how the nuclear envelope controls gene regulatory elements	18
Nucleosomes in mammalian sperm: conveying paternal epigenetic inheritance or subject to reprogramming between generations?	17
A haystack in the needle: packaging sperm DNA in insects	17
Intestinal epithelial organoids: regeneration and maintenance of the intestinal epithelium	17
The Yin and Yang of replicative aging and rejuvenation	17
Biological roles of nonsense-mediated RNA decay: insights from the nervous system	17
Multi-organelle-mediated mRNA localization in neurons and links to disease	17
Epigenetic priming in the male germline	16
Meiotic drive of noncentromeric loci in mammalian meiosis II eggs	16
Shaping inheritance: how distinct reproductive strategies influence DNA methylation memory in plants	16
Evolution of 3D chromatin organization at different scales	16
What are tethering elements?	16
Maternal genetic factors in the development of congenital heart defects	16
Editorial overview: Peering into our history through a genetic lens: How advances in genetics are changing our understanding of human evolution	16
Cancer-associated chromatin variants uncover the oncogenic role of transposable elements	16
RNA interference therapeutics for cardiac regeneration	16
Chromatin architecture reorganization during somatic cell reprogramming	15
Editorial Board	15
Cell identity conversion in liver regeneration after injury	15
Rewiring cancer: 3D genome determinants of cancer hallmarks	14
Discrete roles for Rad54 and Rdh54 during homologous recombination	14
Inheritance of epigenetic transcriptional memory	14
Advances in skeletal genomics research across tissues and cells	14
Songbird germline-restricted chromosome as a potential arena of genetic conflicts	14
Deciphering microglia phenotypes in health and disease	14
Editorial overview: Epigenetic inheritance: A shortcut to environmental adaptation?	14

Cellular plasticity in the neural crest and cancer	13
Amending the injured heart by in vivo reprogramming	13
Editorial overview: Epitranscriptomics: Exploring a new frontier in health and disease	13
Editorial overview: Regaining architecture and cell cross-talk upon regeneration	13
Transposable elements in early human embryo development and embryo models	13
Architecture of RNA–RNA interactions	13
A new era of understanding in vivo metabolic flux in thermogenic adipocytes	13
Approaches to probe and perturb long noncoding RNA functions in diseases	13
Editorial Board	13
Alterations in transcriptional networks in cancer: the role of noncoding somatic driver mutations	13
Adipose tissue lipid metabolism: lipolysis	13
DNA helicases in homologous recombination repair	13
Cellular identity through the lens of direct lineage reprogramming	12
Toward a comprehensive view of gene architecture during transcription	12
Evolution and molecular bases of reproductive isolation	12
Challenges and potential solutions for studying the genetic and phenotypic architecture of adaptation in microbes	12
Correlation between protein abundance and sequence conservation: what do recent experiments say?	12
The stem cell zoo for comparative studies of developmental tempo	12
Recent developments in adipose tissue-secreted factors and their target organs	12
Editorial overview: The genome in space–time	12
Principles of genome activation in the early embryo	12
Brain organoids: the quest to decipher human-specific features of brain development	12
Dissecting nephron morphogenesis using kidney organoids from human pluripotent stem cells	11
Editorial Board	11
In vitro models of human hypoblast and mouse primitive endoderm	11
3D chromosomal architecture in germinal center B cells and its alterations in lymphomagenesis	11
Paternal genome elimination: patterns and mechanisms of drive and silencing	11
The role of loop extrusion in enhancer-mediated gene activation	11
Transcriptional regulation of T cell metabolism and metabolic control of T cell gene expression	11
Alternative splicing in addiction	11
Exploring conditional gene essentiality through systems genetics approaches in yeast	11
Phase separation and inheritance of repressive chromatin domains	11
Microbial experimental evolution in a massively multiplexed and high-throughput era	11
Mechanism of mitotic recombination: insights from C. elegans	11
Editorial Board	11
An extending ATR–CHK1 circuitry: the replication stress response and beyond	11
Epistasis and evolutionary dependencies in human cancers	11
Oncogenic fusion proteins and their role in three-dimensional chromatin structure, phase separation, and cancer	11
Genome folding dynamics during the M-to-G1-phase transition	11
In search of conserved principles of planar cell polarization	11
Editorial Board	11
Bridging spatial and temporal scales of developmental gene regulation	11
The metabolic baton: conducting the dance of N6-methyladenosine writing and erasing	10
The role of tissue maturity and mechanical state in controlling cell extrusion	10
When 3D genome changes cause disease: the impact of structural variations in congenital disease and cancer	10
Topical section: embryonic models (2023) for Current Opinion in Genetics & Development	10
Polycomb complexes in MLL–AF9-related leukemias	10
Reconstitution of reproductive organ system that produces functional oocytes	10
The role of SAF-A/hnRNP U in regulating chromatin structure	10
Timing mechanisms: insights from comparative neural differentiation systems	10
Chromosome organization in 4D: insights from C. elegans development	10
Proliferation and dissemination of killer meiotic drive loci	10
Can we stop one heart from breaking: triumphs and challenges in cardiac reprogramming	9
Principles of long-range gene regulation	9
The transcription factor code in iPSC reprogramming	9
The genetic landscape of cardiovascular left–right patterning defects	9
The power of proximity: mechanisms and biological roles of transvection	9
Spliceosome complex and neurodevelopmental disorders	9
Transposon persistence and control in germ cells	9
Recent advances in stem cell-based blastocyst models	9
R-loop homeostasis in genome dynamics, gene expression and development	9
Jack of all trades versus master of one: how generalist versus specialist strategies of transposable elements relate to their horizontal transfer between lineages	9
Hijacked enhancer–promoter and silencer–promoter loops in cancer	9
Cellular diversity and developmental hierarchy in the planarian nervous system	9
Prospects for precision genetic medicine in congenital heart disease	8
Ex situ-armus: experimental models for combating respiratory dysfunction	8
Pediatric CNS cancer genomics and immunogenomics	8
Recent insights into the in vitro culture systems for mammalian embryos	8
Quantitative mapping of the mammalian epitranscriptome	8
Unlocking regeneration: how partial reprogramming resembles tissue healing	8
Mitochondrial curation for the next generation	8
Modification of the RNA methylome in neurodevelopmental disorders	8
Decoding N6-methyladenosine’s dynamic role in stem cell fate and early embryo development: insights into RNA–chromatin interactions	8
To splice or not to splice: pseudoexons in neurological disease and opportunities for intervention	8
Clinical Perspectives in Epitranscriptomics	8
Experimental evolution of drug resistance in human fungal pathogens	8
Epigenetic dynamics during germline development: insights from Drosophila and C. elegans	8
Distinct fibroblasts in scars and regeneration	7
Female meiotic drive in plants: mechanisms and dynamics	7
Do sex-linked male meiotic drivers contribute to intrinsic hybrid incompatibilities? Recent empirical studies from flies and rodents	7

Xenotransplantation — a shortcut to construct tissue complexity in organoids	7
Mechanisms of regulatory evolution in yeast	7
Linking mitochondria metabolism, developmental timing, and human brain evolution	7
Temporal patterning of the vertebrate developing neural tube	7
The WRN helicase: resolving a new target in microsatellite unstable cancers	7
Pancreatic cell fate specification: insights into developmental mechanisms and their application for lineage reprogramming	7
The ribonucleoprotein network of the nucleus: a historical perspective	7
Circuit integration by transplanted human neurons	7
Editorial Board	7
Corneal regeneration: insights in epithelial stem cell heterogeneity and dynamics	7
Chromosomal instability as a source of genomic plasticity	7
Vascular and immune interactions in islets transplantation and 3D islet models	7
Evolutionary neurogenomics at single-cell resolution	7
Reprogramming cellular identity during intestinal regeneration	7
Pluripotent stem cell–derived mesenchymal stem cells for therapeutic applications, developmental study, and cancer research	6
Factors that determine cell type–specific CTCF binding in health and disease	6
Therapeutic index of targeting select chromatin complexes in human cancer patients	6
A new era in neuromuscular junction research: current advances in self-organized and assembled in vitro models	6
Adipocyte plasticity in tissue regeneration, repair, and disease	6
Extracellular vesicles for remote brain repair	6
The ever-growing world of gastruloids: autogenous models of mammalian embryogenesis	6
Overcoming muscle stem cell aging	6
Network models of chromatin structure	6
NOVA1/2 genes and alternative splicing in neurodevelopment	6
Engineering immune organoids to regenerate host immune system	6
RAD51 paralog function in replicative DNA damage and tolerance	6
When and why are mitochondria paternally inherited?	6
Extending the spectrum in aortopathy: stenosis to aneurysm	6
Concepts, mechanisms and implications of long-term epigenetic inheritance	6
Transgenerational epigenetic control of constitutive heterochromatin, transposons, and centromeres	6
Recombination-dependent replication: new perspectives from site-specific fork barriers	6
Interplay of transposable elements and ageing: epigenetic regulation and potential epitranscriptomic influence	6
Recent insights into the evolution of mutation rates in yeast	6
Advancements in inner ear development, regeneration, and repair through otic organoids	6
Early central nervous system development and neuron regeneration	6
Deciphering the role of structural variation in human evolution: a functional perspective	6
Narrative engineering of the liver	6
Metabolic regulation of cardiac regeneration: roles of hypoxia, energy homeostasis, and mitochondrial dynamics	6
Insights into multilevel spatial regulation within the root stem cell niche	6
Rethinking chromatin accessibility: from compaction to dynamic interactions	5
Editorial overview: Early embryonic development models: back to the beginning	5
Human trophoblast stem cell-state acquisition from pluripotent stem cells and somatic cells	5
Genomic snowflakes: how the uniqueness of DNA folding allows us to smell the chemical universe	5
Editorial Board	5
Chromatin and aberrant enhancer activity in KMT2A rearranged acute lymphoblastic leukemia	5
Multi-scale dynamics of heterochromatin repair	5
A finger on the pulse of regeneration: insights into the cellular mechanisms of adult digit tip regeneration	5
A lifelong duty: how Xist maintains the inactive X chromosome	5
Editorial overview: Fat tissue in focus: Assembled deeply insightful perspectives on state-of-the-art explorations	5
Decoding the role of tRNA modifications in cancer progression	5
Spatial orchestration of the genome: topological reorganisation during X-chromosome inactivation	5
Molecular mechanisms of the specialization of human synapses in the neocortex	5
Plasticity of muscle stem cells in homeostasis and aging	5
Somatic mutation burden in relation to aging and functional life span: implications for cellular reprogramming and rejuvenation	5
Safeguarding the epigenome through the cell cycle: a multitasking game	5
Editorial overview: New insights into epithelial dynamics: From tissue homeostasis to morphogenesis	5
Recent advances in RNA-based therapeutics for neurodevelopmental disorders	5