OOIR: Observatory of International Research

Papers

(The TQCC of Current Opinion in Genetics & Development is 13. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-05-01 to 2024-05-01.)

Article	Citations
Enhancer-promoter communication: hubs or loops?	94
Spatially resolved transcriptomics and its applications in cancer	62
To loop or not to loop: what is the role of TADs in enhancer function and gene regulation?	50
Role of VPS13, a protein with similarity to ATG2, in physiology and disease	49
Evolution of sexual development and sexual dimorphism in insects	47
Diverse lncRNA mechanisms in brain development and disease	44
16p11.2 deletion syndrome	44
Single-molecule tracking of transcription protein dynamics in living cells: seeing is believing, but what are we seeing?	43
Copy number variation and neuropsychiatric illness	42
Evolution of the mutation rate across primates	41
Regulation of 3D chromatin organization by CTCF	40
Advances in colon cancer research: in vitro and animal models	37
Microexons: at the nexus of nervous system development, behaviour and autism spectrum disorder	36
Evolution of pigment cells and patterns: recent insights from teleost fishes	36
4D nucleome modeling	35
Structure-forming repeats and their impact on genome stability	33
The evolution of structural colour in butterflies	32
Epigenetic regulation of mouse preimplantation embryo development	31
Nuclear mechanisms of gene expression control: pre-mRNA splicing as a life or death decision	31
Microglial ontogeny, diversity and neurodevelopmental functions	31
The evolution of the human brain and disease susceptibility	31
Advances in repeat expansion diseases and a new concept of repeat motif–phenotype correlation	30
The role of clustered protocadherins in neurodevelopment and neuropsychiatric diseases	30
African population history: an ancient DNA perspective	30
Extrachromosomal DNA (ecDNA) in cancer pathogenesis	29

New gene discoveries highlight functional convergence in autism and related neurodevelopmental disorders	28
An extending ATR–CHK1 circuitry: the replication stress response and beyond	28
Diagnostic genetic testing for neurodevelopmental psychiatric disorders: closing the gap between recommendation and clinical implementation	28
Generations of genomes: advances in paleogenomics technology and engagement for Indigenous people of the Americas	27
Poison exons in neurodevelopment and disease	27
Rising from the ashes: cellular senescence in regeneration	27
The nuclear pore complex and the genome: organizing and regulatory principles	26
Break-induced replication mechanisms in yeast and mammals	26
The shifting shape of genomes: dynamics of heterochromatin interactions at the nuclear lamina	26
A cell in hand is worth two in the embryo: recent advances in 2-cell like cell reprogramming	26
The transcription factor code in iPSC reprogramming	25
Activity regulates brain development in the fly	25
Exosomes in cancer development	25
Inferring evolutionary dynamics of mutation rates through the lens of mutation spectrum variation	25
Disentangling the paradox of the PCDH19 clustering epilepsy, a disorder of cellular mosaics	24
DNA end resection during homologous recombination	24
Experimental embryology of gastrulation: pluripotent stem cells as a new model system	23
Cortico-basal ganglia circuits underlying dysfunctional control of motor behaviors in neuropsychiatric disorders	23
Waiting on the Fringe: cell autonomy and signaling delays in segmentation clocks	22
Mechanisms of maternal intergenerational epigenetic inheritance	22
LINC complex regulation of genome organization and function	22
Active nematics across scales from cytoskeleton organization to tissue morphogenesis	22
Human adaptation over the past 40,000 years	21
H3–H4 histone chaperones and cancer	21
The mouse alpha-globin cluster: a paradigm for studying genome regulation and organization	21
Evo-devo of shell colour in gastropods and bivalves	20
Engineering and modeling of multicellular morphologies and patterns	20
The dawn of non-human primate models for neurodevelopmental disorders	20
The role of somatic mosaicism in brain disease	20
Insights into clonal hematopoiesis and its relation to cancer risk	20
Genetic pathways involved in human speech disorders	20
Digesting the mechanobiology of the intestinal epithelium	20
Control of cell shape during epithelial morphogenesis: recent advances	20
Mitotic recombination in yeast: what we know and what we don’t know	19
Update on Müller glia regenerative potential for retinal repair	19
Molecular mechanisms for targeted ASD treatments	19
RAD51 paralog function in replicative DNA damage and tolerance	19
Xeno-organ donor pigs with multiple genetic modifications – the more the better?	19
Replication stress: from chromatin to immunity and beyond	19
Serine ADP-ribosylation in DNA-damage response regulation	19
The stochastic nature of genome organization and function	19
Human evolutionary history in Eastern Eurasia using insights from ancient DNA	18
Prime time for primate functional genomics	18
The dynamics of chromatin architecture in brain development and function	18
Olfactory receptor choice: a case study for gene regulation in a multi-enhancer system	18
The evolution of post-translational modifications	18
Distinct fibroblasts in scars and regeneration	18
Recent insights into zebrafish cardiac regeneration	17
Homologous recombination within repetitive DNA	17
The role of loop extrusion in enhancer-mediated gene activation	17

Stabilizing hematopoietic stem cells in vitro	17
Linking genotype, cell behavior, and phenotype: multidisciplinary perspectives with a basis in zebrafish patterns	17
How gene duplication diversifies the landscape of protein oligomeric state and function	16
The use of CRISPR/Cas9-based gene editing strategies to explore cancer gene function in mice	16
Pigmentation and color pattern diversity in Odonata	16
Structural and functional brain alterations revealed by neuroimaging in CNV carriers	16
Latest trends in archaeogenetic research of west Eurasians	16
Somatic variants in epilepsy – advancing gene discovery and disease mechanisms	16
Recombination and restart at blocked replication forks	16
Regeneration in the spiny mouse, Acomys, a new mammalian model	16
The WRN helicase: resolving a new target in microsatellite unstable cancers	16
Cellular and developmental basis of avian structural coloration	16
The role of SAF-A/hnRNP U in regulating chromatin structure	16
Noncanonical imprinting: intergenerational epigenetic inheritance mediated by Polycomb complexes	16
Collective effects in epithelial cell death and cell extrusion	16
ERK signaling dynamics in the morphogenesis and homeostasis of Drosophila	16
Mechanical induction and competence in epithelial morphogenesis	15
What a finding of gene copy number variation can add to the diagnosis of developmental neuropsychiatric disorders	15
Multi-scale dynamics of heterochromatin repair	15
Chromosomal instability as a source of genomic plasticity	15
Histone isoforms and the oncohistone code	14
Metal ion availability and homeostasis as drivers of metabolic evolution and enzyme function	14
The X chromosome in C. elegans sex determination and dosage compensation	14
All for one and one for all: heterogeneity of genetic etiologies in neurodevelopmental psychiatric disorders	14
Evolution of 3D chromatin organization at different scales	13
Seasonal plasticity: how do butterfly wing pattern traits evolve environmental responsiveness?	13
7q11.23 deletion and duplication	13
What crustaceans can tell us about the evolution of insect wings and other morphologically novel structures	13
Stem-cell-based human and mouse embryo models	13
Homologous recombination deficiency: how genomic signatures are generated	13
A lifelong duty: how Xist maintains the inactive X chromosome	13
Challenges of diagnostic genomics in Latin America	13