OOIR: Observatory of International Research

Papers

(The TQCC of Current Opinion in Genetics & Development is 13. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
Editorial Board	70
Editorial Board	69
Editorial Board	55
Editorial overview: Conflicts, conflicts everywhere	55
Epithelial–immune crosstalk in health and disease	49
R-loops in neurodegeneration	48
Tile by tile: capturing the evolutionary mosaic of human conditions	40
Adipose tissue endothelial cells: insights into their heterogeneity and functional diversity	38
Integrative approaches to study enhancer–promoter communication	35
Evolution and ecology of commensal gut protists: recent advances	35
The X chromosome in C. elegans sex determination and dosage compensation	33
Convergence and divergence of molecular phenotypes in iPSC-derived models of 16p11.2 and 22q11.2 reciprocal copy number variants	32
Loops, crosstalk, and compartmentalization: it takes many layers to regulate DNA methylation	31
A critical role for X-chromosome architecture in mammalian X-chromosome dosage compensation	30
Why is measuring and predicting fitness under genomic conflict so hard?	30
Therapeutic strategies to target the epitranscriptomic machinery	29
Editorial Board	29
Genetic clues to reprogramming power and formation of mouse oocyte	28
In vitro models of pre- and post-gastrulation embryonic development	28
Mitochondrial metabolism and the continuing search for ultimate regulators of developmental rate	27
High-throughput approaches to functional characterization of genetic variation in yeast	27
Control of cell fate upon transcription factor–driven cardiac reprogramming	27
Toward the dissection of hematopoietic stem cell fates and their determinants	27
Exploring the origin of the development: totipotent stem cells	26
NAT10 and cytidine acetylation in mRNA: intersecting paths in development and disease	25

Single-cell genomic profiling to study regeneration	25
Interplay between N-adenosine RNA methylation and mRNA splicing	25
Cell–cell interactions between transplanted retinal organoid cells and recipient tissues	24
Using human pluripotent stem cells to dissect trophoblast development	23
Adipose tissue-derived lipokines in metabolism	23
If you please, draw me a neuron — linking evolutionary tinkering with human neuron evolution	23
Structural variation in humans and our primate kin in the era of telomere-to-telomere genomes and pangenomics	23
Recent advances in the neurogenomics of autism spectrum disorder	23
Transposon waves at the water-to-land transition	22
Editorial Board	22
Timers, variability, and body-wide coordination: C. elegans as a model system for whole-animal developmental timing	22
Molecular genetics of pulmonary hypertension in children	22
Dynamic microenvironments shape nuclear organization and gene expression	22
Emerging oligo-based imaging methods to study chromatin organization in cells and tissue	21
Stem-cell-based human and mouse embryo models	21
Genetic disruption of nonsense-mediated mRNA decay in neurodevelopmental disorders	20
Better together: how cooperativity influences transcriptional bursting	20
Nucleosomes in mammalian sperm: conveying paternal epigenetic inheritance or subject to reprogramming between generations?	19
Genome instability in mammalian embryos implications for genome editing, development, and evolution	19
Editorial overview: Drivers, droplets, and deeds of nuclear genome organization	19
Behavioral evolution by diverging cell type composition	19
Enhancers on the edge — how the nuclear envelope controls gene regulatory elements	18
Human 8-cell embryo-like cells from pluripotent stem cells	18
The Yin and Yang of replicative aging and rejuvenation	18
Nuclear remodeling during cell fate transitions	17
Modifying gastruloids to dissect mechanisms of tissue-specific induction	17
Linking phenotype to genotype using comprehensive genomic comparisons	17
Chromosome organization by Structural Maintenance of Chromosomes complexes in C. elegans	17
A haystack in the needle: packaging sperm DNA in insects	17
Editorial Board	17
Intestinal epithelial organoids: regeneration and maintenance of the intestinal epithelium	17
Editorial overview: Multiscale regulation of genome folding in space, time, and across the tree of life	17
Multi-organelle-mediated mRNA localization in neurons and links to disease	17
Recipes and ingredients for deep learning models of 3D genome folding	17
Shaping inheritance: how distinct reproductive strategies influence DNA methylation memory in plants	16
Editorial overview: Epigenetic inheritance: A shortcut to environmental adaptation?	16
Evolution of 3D chromatin organization at different scales	16
Cell identity conversion in liver regeneration after injury	16
Epigenetic priming in the male germline	16
Editorial overview: Peering into our history through a genetic lens: How advances in genetics are changing our understanding of human evolution	16
Biological roles of nonsense-mediated RNA decay: insights from the nervous system	16
Approaches to probe and perturb long noncoding RNA functions in diseases	16
Deciphering microglia phenotypes in health and disease	16
What are tethering elements?	16
Meiotic drive of noncentromeric loci in mammalian meiosis II eggs	16
Editorial Board	16
Maternal genetic factors in the development of congenital heart defects	16
Cancer-associated chromatin variants uncover the oncogenic role of transposable elements	15
Transposable elements in early human embryo development and embryo models	15
Editorial overview: Regaining architecture and cell cross-talk upon regeneration	15

Editorial overview: Epitranscriptomics: Exploring a new frontier in health and disease	15
Songbird germline-restricted chromosome as a potential arena of genetic conflicts	15
Amending the injured heart by in vivo reprogramming	15
Mix-and-match between transposable elements and zinc finger proteins fuels genic and regulatory innovation	15
Inheritance of epigenetic transcriptional memory	15
Advances in skeletal genomics research across tissues and cells	15
Editorial Board	15
Rewiring cancer: 3D genome determinants of cancer hallmarks	15
Cellular plasticity in the neural crest and cancer	14
Adipose tissue lipid metabolism: lipolysis	14
Recent developments in adipose tissue-secreted factors and their target organs	14
Alterations in transcriptional networks in cancer: the role of noncoding somatic driver mutations	14
A new era of understanding in vivo metabolic flux in thermogenic adipocytes	14
Correlation between protein abundance and sequence conservation: what do recent experiments say?	14
Cooperativity between regulatory elements acts as a modulator of enhancer function	14
Decoding schizophrenia through postmortem human brain transcriptomics	14
Toward a comprehensive view of gene architecture during transcription	13
Evolution and molecular bases of reproductive isolation	13
Editorial Board	13
Brain organoids: the quest to decipher human-specific features of brain development	13
Challenges and potential solutions for studying the genetic and phenotypic architecture of adaptation in microbes	13
Genome folding dynamics during the M-to-G1-phase transition	13
Principles of genome activation in the early embryo	13
Editorial overview: The genome in space–time	13
The stem cell zoo for comparative studies of developmental tempo	13
Evolutionary genetics meets ecological immunology: insights into the evolution of immune systems	13
Microbial experimental evolution in a massively multiplexed and high-throughput era	13