OOIR: Observatory of International Research

Papers

(The TQCC of Current Opinion in Genetics & Development is 11. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)

Article	Citations
Epithelial–immune crosstalk in health and disease	71
Editorial Board	70
Editorial Board	65
Editorial Board	49
Why is measuring and predicting fitness under genomic conflict so hard?	45
Loops, crosstalk, and compartmentalization: it takes many layers to regulate DNA methylation	43
Editorial overview: Conflicts, conflicts everywhere	43
The X chromosome in C. elegans sex determination and dosage compensation	40
R-loops in neurodegeneration	39
Integrative approaches to study enhancer–promoter communication	38
Adipose tissue endothelial cells: insights into their heterogeneity and functional diversity	38
A critical role for X-chromosome architecture in mammalian X-chromosome dosage compensation	36
Tile by tile: capturing the evolutionary mosaic of human conditions	34
Break-induced replication mechanisms in yeast and mammals	33
DNA end resection during homologous recombination	32
Editorial Board	32
In vitro models of pre- and post-gastrulation embryonic development	31
Therapeutic strategies to target the epitranscriptomic machinery	31
High-throughput approaches to functional characterization of genetic variation in yeast	28
Control of cell fate upon transcription factor–driven cardiac reprogramming	28
Genetic clues to reprogramming power and formation of mouse oocyte	28
Mitochondrial metabolism and the continuing search for ultimate regulators of developmental rate	27
Interplay between N-adenosine RNA methylation and mRNA splicing	27
NAT10 and cytidine acetylation in mRNA: intersecting paths in development and disease	26
Structural and functional brain alterations revealed by neuroimaging in CNV carriers	26

Toward the dissection of hematopoietic stem cell fates and their determinants	25
Reprogramming lineage identity through cell–cell fusion	25
Epigenetic memory in reprogramming	25
Single-cell genomic profiling to study regeneration	24
Recombination-mediated genome rearrangements	24
If you please, draw me a neuron — linking evolutionary tinkering with human neuron evolution	24
Cell–cell interactions between transplanted retinal organoid cells and recipient tissues	24
Using human pluripotent stem cells to dissect trophoblast development	24
Something old, something new, something borrowed, something red: the origin of ecologically relevant novelties in Hemiptera	23
Better together: how cooperativity influences transcriptional bursting	23
Dynamic microenvironments shape nuclear organization and gene expression	23
Editorial Board	23
Timers, variability, and body-wide coordination: C. elegans as a model system for whole-animal developmental timing	23
Structural variation in humans and our primate kin in the era of telomere-to-telomere genomes and pangenomics	23
Adipose tissue-derived lipokines in metabolism	23
How strand exchange protein function benefits from ATP hydrolysis	22
Transposon waves at the water-to-land transition	22
Molecular genetics of pulmonary hypertension in children	22
Stem-cell-based human and mouse embryo models	22
Editorial overview: Drivers, droplets, and deeds of nuclear genome organization	21
Editorial overview: Recombination — the ends justify the means	21
Nuclear remodeling during cell fate transitions	20
Modifying gastruloids to dissect mechanisms of tissue-specific induction	20
Intestinal epithelial organoids: regeneration and maintenance of the intestinal epithelium	20
Editorial overview: Multiscale regulation of genome folding in space, time, and across the tree of life	20
Enhancers on the edge — how the nuclear envelope controls gene regulatory elements	19
Digesting the mechanobiology of the intestinal epithelium	19
Copy number variants in neurexin genes: phenotypes and mechanisms	19
Multi-organelle-mediated mRNA localization in neurons and links to disease	19
Eco-evo-devo advances with butterfly eyespots	18
What are tethering elements?	18
Nucleosomes in mammalian sperm: conveying paternal epigenetic inheritance or subject to reprogramming between generations?	18
Recipes and ingredients for deep learning models of 3D genome folding	18
Human 8-cell embryo-like cells from pluripotent stem cells	18
Editorial overview: Peering into our history through a genetic lens: How advances in genetics are changing our understanding of human evolution	18
RNA interference therapeutics for cardiac regeneration	17
Meiotic drive of noncentromeric loci in mammalian meiosis II eggs	17
Evolution of 3D chromatin organization at different scales	17
Shaping inheritance: how distinct reproductive strategies influence DNA methylation memory in plants	17
Epigenetic priming in the male germline	17
DNA helicases in homologous recombination repair	16
Maternal genetic factors in the development of congenital heart defects	16
Cancer-associated chromatin variants uncover the oncogenic role of transposable elements	16
Cell identity conversion in liver regeneration after injury	16
Inheritance of epigenetic transcriptional memory	16
Editorial Board	16
Discrete roles for Rad54 and Rdh54 during homologous recombination	16
Editorial overview: Epigenetic inheritance: A shortcut to environmental adaptation?	15
Advances in skeletal genomics research across tissues and cells	15
Approaches to probe and perturb long noncoding RNA functions in diseases	15

A complex gene regulatory architecture underlies the development and evolution of cuticle morphology in Drosophila	15
Chromatin architecture reorganization during somatic cell reprogramming	15
Trends and variation in vertebrate patterns as outcomes of self-organization	14
Songbird germline-restricted chromosome as a potential arena of genetic conflicts	14
Deciphering microglia phenotypes in health and disease	14
Transposable elements in early human embryo development and embryo models	13
Editorial overview: Epitranscriptomics: Exploring a new frontier in health and disease	13
Editorial Board	13
Rewiring cancer: 3D genome determinants of cancer hallmarks	13
Cellular plasticity in the neural crest and cancer	13
Editorial overview: Regaining architecture and cell cross-talk upon regeneration	13
Correlation between protein abundance and sequence conservation: what do recent experiments say?	13
A new era of understanding in vivo metabolic flux in thermogenic adipocytes	13
Architecture of RNA–RNA interactions	12
Alterations in transcriptional networks in cancer: the role of noncoding somatic driver mutations	12
Editorial overview: The genome in space–time	12
Toward a comprehensive view of gene architecture during transcription	12
The stem cell zoo for comparative studies of developmental tempo	12
Cellular and developmental basis of avian structural coloration	12
Regional patterning and regulation of melanin pigmentation in insects	12
Challenges and potential solutions for studying the genetic and phenotypic architecture of adaptation in microbes	12
Principles of genome activation in the early embryo	12
Amending the injured heart by in vivo reprogramming	12
7q11.23 deletion and duplication	12
Adipose tissue lipid metabolism: lipolysis	12
Evolution and molecular bases of reproductive isolation	12
Cellular identity through the lens of direct lineage reprogramming	12
Evolution of sexual development and sexual dimorphism in insects	11
Editorial Board	11
Oncogenic fusion proteins and their role in three-dimensional chromatin structure, phase separation, and cancer	11
Microbial experimental evolution in a massively multiplexed and high-throughput era	11
Bridging spatial and temporal scales of developmental gene regulation	11
Epistasis and evolutionary dependencies in human cancers	11
3D chromosomal architecture in germinal center B cells and its alterations in lymphomagenesis	11
Exploring conditional gene essentiality through systems genetics approaches in yeast	11
The role of loop extrusion in enhancer-mediated gene activation	11
Topical section: embryonic models (2023) for Current Opinion in Genetics & Development	11
Phase separation and inheritance of repressive chromatin domains	11
Mechanism of mitotic recombination: insights from C. elegans	11
Brain organoids: the quest to decipher human-specific features of brain development	11
Editorial Board	11
Alternative splicing in addiction	11
In vitro models of human hypoblast and mouse primitive endoderm	11
Transcriptional regulation of T cell metabolism and metabolic control of T cell gene expression	11
A cross-comparison of cognitive ability across 8 genomic disorders	11
An extending ATR–CHK1 circuitry: the replication stress response and beyond	11
Recent developments in adipose tissue-secreted factors and their target organs	11
Dissecting nephron morphogenesis using kidney organoids from human pluripotent stem cells	11
Genome folding dynamics during the M-to-G1-phase transition	11