OOIR: Observatory of International Research

Papers

(The TQCC of Current Opinion in Genetics & Development is 11. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Editorial Board	127
Rewiring cancer: 3D genome determinants of cancer hallmarks	78
Decoding N6-methyladenosine’s dynamic role in stem cell fate and early embryo development: insights into RNA–chromatin interactions	68
Editorial Board	67
Chromatin and aberrant enhancer activity in KMT2A rearranged acute lymphoblastic leukemia	61
Crosstalk between histone/DNA modifications and RNA N6-methyladenosine modification	56
Editorial Board	48
Editorial overview: evolutionary genetics: how a tiny model system enables big discoveries	48
Editorial Board	47
Integrative approaches to study enhancer–promoter communication	43
Why is measuring and predicting fitness under genomic conflict so hard?	41
Editorial Board	40
Editorial Board	40
Editorial overview: New insights into epithelial dynamics: From tissue homeostasis to morphogenesis	40
Interplay between Sae2 and Rif2 in the regulation of Mre11-Rad50 activities at DNA ends	38
Maternal genetic factors in the development of congenital heart defects	38
Ex situ-armus: experimental models for combating respiratory dysfunction	36
Epithelial–immune crosstalk in health and disease	35
Human blastoid as an in vitro model of human blastocysts	35
In vivo conversion of dopamine neurons in mouse models of Parkinson’s disease — a future approach for regenerative therapy?	34
A critical role for X-chromosome architecture in mammalian X-chromosome dosage compensation	32
Role of RNA modifications in cancer metastasis	31
Clinical Perspectives in Epitranscriptomics	30
Spatial metabolomics in tissue injury and regeneration	30
Quantitative mapping of the mammalian epitranscriptome	29

Adipose tissue endothelial cells: insights into their heterogeneity and functional diversity	29
A complex gene regulatory architecture underlies the development and evolution of cuticle morphology in Drosophila	28
Mechanisms of maternal intergenerational epigenetic inheritance	28
DNA helicases in homologous recombination repair	26
From Aedes to Zeugodacus: a review of dipteran body coloration studies regarding evolutionary developmental biology, pest control, and species discovery	26
The origins of cancer cell dormancy	26
Homologous recombination within repetitive DNA	26
Chromatin architecture reorganization during somatic cell reprogramming	26
Break-induced replication mechanisms in yeast and mammals	26
Cell identity conversion in liver regeneration after injury	25
Trends and variation in vertebrate patterns as outcomes of self-organization	25
Evolution of short linear motifs and disordered proteins Topic: yeast as model system to study evolution	24
Shaping the mouse heart tube from the second heart field epithelium	24
Loops, crosstalk, and compartmentalization: it takes many layers to regulate DNA methylation	23
Editorial overview: Epigenetic inheritance: A shortcut to environmental adaptation?	23
Approaches to probe and perturb long noncoding RNA functions in diseases	22
Human-specific genetic modifiers of cortical architecture and function	22
Recent insights into N6-methyladenosine during viral infection	22
Deciphering microglia phenotypes in health and disease	21
Cancer epitranscriptomics in a nutshell	21
Tile by tile: capturing the evolutionary mosaic of human conditions	21
Editorial overview: Fat tissue in focus: Assembled deeply insightful perspectives on state-of-the-art explorations	21
Unveiling the potential: implications of successful somatic cell-to-ganglion organoid reprogramming	21
Cancer-associated chromatin variants uncover the oncogenic role of transposable elements	20
Songbird germline-restricted chromosome as a potential arena of genetic conflicts	20
Advances in skeletal genomics research across tissues and cells	20
Editorial overview: Conflicts, conflicts everywhere	20
Refining the role of N6-methyladenosine in cancer	20
Clinical evaluation of patients with a neuropsychiatric risk copy number variant	20
H3–H4 histone chaperones and cancer	19
Making region-specific integumentary organs in birds: evolution and modifications	19
RNA in chromatin organization and nuclear architecture	19
How gene duplication diversifies the landscape of protein oligomeric state and function	19
The X chromosome in C. elegans sex determination and dosage compensation	19
Transposable elements in early human embryo development and embryo models	18
How our brains are built: emerging approaches to understand human-specific features	18
DNA end resection during homologous recombination	18
Discrete roles for Rad54 and Rdh54 during homologous recombination	18
Marvels of spiny mouse regeneration: cellular players and their interactions in restoring tissue architecture in mammals	17
Temporal patterning of the vertebrate developing neural tube	17
Inheritance of epigenetic transcriptional memory	17
Corneal regeneration: insights in epithelial stem cell heterogeneity and dynamics	17
The WRN helicase: resolving a new target in microsatellite unstable cancers	17
Mitochondrial metabolism and the continuing search for ultimate regulators of developmental rate	17
Modeling X-chromosome inactivation and reactivation during human development	16
Editorial Board	16
Recent insights into the in vitro culture systems for mammalian embryos	16
Exploiting the plasticity of cholangiocytes to repair the biliary tree	16
Editorial overview: Epitranscriptomics: Exploring a new frontier in health and disease	16
RNA editing and immune control: from mechanism to therapy	16

Chromosomal instability as a source of genomic plasticity	15
Architecture of RNA–RNA interactions	15
Editorial overview: Understanding the biology of cancer genomes in the context of DNA, RNA, histone marks, and 3D chromatin organization	15
Editorial Board	15
Adipocyte gene expression in obesity — insights gained and challenges ahead	15
Editorial Board	14
Alterations in transcriptional networks in cancer: the role of noncoding somatic driver mutations	14
Correlation between protein abundance and sequence conservation: what do recent experiments say?	14
Therapeutic strategies to target the epitranscriptomic machinery	14
Pediatric CNS cancer genomics and immunogenomics	14
Cellular and developmental basis of avian structural coloration	13
Human embryo models: the importance of national policy and governance review	13
Genetic approaches to revealing the principles of nuclear architecture	13
Somatic copy number variants in neuropsychiatric disorders	13
Understanding and evolving prions by yeast multiplexed assays	13
Resources and challenges for integrative analysis of nuclear architecture data	13
Interplay between N-adenosine RNA methylation and mRNA splicing	13
Key mechanisms and in vitro reconstitution of fetal oocyte development in mammals	13
Structural and functional brain alterations revealed by neuroimaging in CNV carriers	12
Control of cell fate upon transcription factor–driven cardiac reprogramming	12
Editorial overview: Cool, colorful, and complex animal systems	12
Dissecting the complexity of CNV pathogenicity: insights from Drosophila and zebrafish models	12
High-throughput approaches to functional characterization of genetic variation in yeast	12
Insights into homology search from cryo-EM structures of RecA-DNA recombination intermediates	12
Emerging interactions between RNA methylation and chromatin architecture	12
Pancreatic cell fate specification: insights into developmental mechanisms and their application for lineage reprogramming	12
Molecular genetic mechanisms of dilated cardiomyopathy	11
Amending the injured heart by in vivo reprogramming	11
Toward the dissection of hematopoietic stem cell fates and their determinants	11
Control of structure-specific endonucleases during homologous recombination in eukaryotes	11
Epithelial morphogenesis in organoids	11
Recent progress in understanding the genomic architecture of sexual conflict	11
Evolutionary dynamics between transposable elements and their host genomes: mechanisms of suppression and escape	11
Revealing epithelial morphogenetic mechanisms through live imaging	11
In vitro models of pre- and post-gastrulation embryonic development	11
Cellular plasticity in the neural crest and cancer	11
A new era of understanding in vivo metabolic flux in thermogenic adipocytes	11
Cell cycle dynamics and developmental dynamics of the 3D genome: toward linking the two timescales	11
Epigenetic dynamics during germline development: insights from Drosophila and C. elegans	11
May the best wound WIHN: the hallmarks of wound-induced hair neogenesis	11
Experimental evolution of drug resistance in human fungal pathogens	11