OOIR: Observatory of International Research

Papers

(The H4-Index of Current Opinion in Structural Biology is 46. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
How molecular modelling can better broaden the understanding of glycosylations	251
HIV-1 gp160 in nanodiscs: Unravelling structures and guiding vaccine design	170
Editorial	144
Next-generation predictors of protein phase behavior	132
Optogenetic enzymes: A deep dive into design and impact	102
Genome modeling: From chromatin fibers to genes	99
Computer-aided drug design, quantum-mechanical methods for biological problems	98
Advancing biomolecular simulation through exascale HPC, AI and quantum computing	96
Access and utilization of long chain fatty acyl-CoA by zDHHC protein acyltransferases	94
Mutational fitness landscape and drug resistance	93
Single-particle Cryo-EM and molecular dynamics simulations: A perfect match	88
May the proton motive force be with you: A plant transporter review	86
Catalysis and structure of nitrogenases	85
Harnessing the 14-3-3 protein–protein interaction network	82
Recent advances in AI-driven pKa prediction for proteins and small molecules	82
Single-point mutations in disordered proteins: Linking sequence, ensemble, and function	78
Raman spectroscopy and imaging of protein droplet formation and aggregation	71
Pump-like channelrhodopsins: Not just bridging the gap between ion pumps and ion channels	71
Structure-based virtual screening of vast chemical space as a starting point for drug discovery	70
Navigating protein–nucleic acid sequence-structure landscapes with deep learning	67
Markov field models: Scaling molecular kinetics approaches to large molecular machines	67
Editorial Board	67
The mannose receptor ligands and the macrophage glycome	64
Proteins with alternative folds reveal blind spots in AlphaFold-based protein structure prediction	62
Molecular dynamics simulations for the study of chromatin biology	61

Advancing protein structure prediction beyond AlphaFold2	61
Deep learning for intrinsically disordered proteins: From improved predictions to deciphering conformational ensembles	61
Advances in native cell membrane nanoparticles system	61
Protein dynamics underlying allosteric regulation	60
Mutually beneficial confluence of structure-based modeling of protein dynamics and machine learning methods	58
Editorial overview: Biophysical methods: Exploring structures in motions, from biomolecules to cells, and how to drug them	57
Mucin networks: Dynamic structural assemblies controlling mucus function	57
NMR tools to detect protein allostery	57
Dynamics and interactions of intrinsically disordered proteins	56
Old and new tactics of CRISPR-centric competition between bacteria and bacteriophages	56
Modeling membranes in situ	55
DDK promotes DNA replication initiation: Mechanistic and structural insights	55
Conformational penalties: New insights into nucleic acid recognition	55
The role of RNA structure in 3’ end processing in eukaryotes	55
The opportunities and challenges posed by the new generation of deep learning-based protein structure predictors	51
Table of contents	51
Table of contents	51
Macromolecular assemblies: Molecular mechanisms abound	50
Probing protein–DNA interactions and compaction in nanochannels	48
Viral amyloids: New opportunities for antiviral therapeutic strategies	46
Insight into the structural dynamics of light sensitive proteins from time-resolved crystallography and quantum chemical calculations	46
NMR of RNA - Structure and interactions	46
CryoEM of V-ATPases: Assembly, disassembly, and inhibition	46