OOIR: Observatory of International Research

Papers

(The H4-Index of Current Opinion in Structural Biology is 45. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)

Article	Citations
Single-particle Cryo-EM and molecular dynamics simulations: A perfect match	174
Single-point mutations in disordered proteins: Linking sequence, ensemble, and function	165
Raman spectroscopy and imaging of protein droplet formation and aggregation	128
How molecular modelling can better broaden the understanding of glycosylations	127
Mutational fitness landscape and drug resistance	124
Editorial	123
Harnessing the 14-3-3 protein–protein interaction network	118
May the proton motive force be with you: A plant transporter review	108
Catalysis and structure of nitrogenases	99
Advancing biomolecular simulation through exascale HPC, AI and quantum computing	93
Pump-like channelrhodopsins: Not just bridging the gap between ion pumps and ion channels	88
Access and utilization of long chain fatty acyl-CoA by zDHHC protein acyltransferases	88
In silico reconstitution of DNA replication. Lessons from single-molecule imaging and cryo-tomography applied to single-particle cryo-EM	83
Computer-aided drug design, quantum-mechanical methods for biological problems	81
Structure-based virtual screening of vast chemical space as a starting point for drug discovery	79
Genome modeling: From chromatin fibers to genes	77
Editorial overview: Biophysical methods: Exploring structures in motions, from biomolecules to cells, and how to drug them	76
NMR tools to detect protein allostery	75
Deep learning for intrinsically disordered proteins: From improved predictions to deciphering conformational ensembles	71
Implications of disease-related mutations at protein–protein interfaces	71
Conformational penalties: New insights into nucleic acid recognition	71
Modeling membranes in situ	70
Markov field models: Scaling molecular kinetics approaches to large molecular machines	67
Advancing protein structure prediction beyond AlphaFold2	66
Editorial Board	65

Dynamics and interactions of intrinsically disordered proteins	65
Structural insights into host–microbe glycointeractions	65
Molecular dynamics simulations for the study of chromatin biology	62
Structure-based analyses of gut microbiome-related proteins by neural networks and molecular dynamics simulations	62
Mutually beneficial confluence of structure-based modeling of protein dynamics and machine learning methods	59
Proteins with alternative folds reveal blind spots in AlphaFold-based protein structure prediction	57
Mucin networks: Dynamic structural assemblies controlling mucus function	57
Gut power: Modulation of human amyloid formation by amyloidogenic proteins in the gastrointestinal tract	56
Protein dynamics underlying allosteric regulation	56
The mannose receptor ligands and the macrophage glycome	53
Interpretable artificial intelligence and exascale molecular dynamics simulations to reveal kinetics: Applications to Alzheimer's disease	52
Principles of nucleosome recognition by chromatin factors and enzymes	52
Inner workings of RAG recombinase and its specialization for adaptive immunity	52
Table of contents	51
Insight into the structural dynamics of light sensitive proteins from time-resolved crystallography and quantum chemical calculations	50
Editorial Board	50
Macromolecular assemblies: Molecular mechanisms abound	50
Table of contents	50
The role of RNA structure in 3’ end processing in eukaryotes	48
Structural insights into assembly of transcription preinitiation complex	47
Challenges and compromises: Predicting unbound antibody structures with deep learning	45
Probing protein–DNA interactions and compaction in nanochannels	45