OOIR: Observatory of International Research

Papers

(The H4-Index of Current Opinion in Structural Biology is 44. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)

Article	Citations
How molecular modelling can better broaden the understanding of glycosylations	192
Editorial	187
Raman spectroscopy and imaging of protein droplet formation and aggregation	141
Advancing biomolecular simulation through exascale HPC, AI and quantum computing	137
HIV-1 gp160 in nanodiscs: Unravelling structures and guiding vaccine design	131
In silico reconstitution of DNA replication. Lessons from single-molecule imaging and cryo-tomography applied to single-particle cryo-EM	116
Access and utilization of long chain fatty acyl-CoA by zDHHC protein acyltransferases	110
Pump-like channelrhodopsins: Not just bridging the gap between ion pumps and ion channels	101
Genome modeling: From chromatin fibers to genes	100
Catalysis and structure of nitrogenases	98
Harnessing the 14-3-3 protein–protein interaction network	84
May the proton motive force be with you: A plant transporter review	84
Single-particle Cryo-EM and molecular dynamics simulations: A perfect match	84
Computer-aided drug design, quantum-mechanical methods for biological problems	83
Single-point mutations in disordered proteins: Linking sequence, ensemble, and function	83
Structure-based virtual screening of vast chemical space as a starting point for drug discovery	78
Optogenetic enzymes: A deep dive into design and impact	78
Editorial Board	77
Mutational fitness landscape and drug resistance	77
Protein dynamics underlying allosteric regulation	76
Mucin networks: Dynamic structural assemblies controlling mucus function	75
NMR tools to detect protein allostery	74
Structure-based analyses of gut microbiome-related proteins by neural networks and molecular dynamics simulations	71
Molecular dynamics simulations for the study of chromatin biology	71
Structural insights into host–microbe glycointeractions	70

Inner workings of RAG recombinase and its specialization for adaptive immunity	65
Gut power: Modulation of human amyloid formation by amyloidogenic proteins in the gastrointestinal tract	63
Editorial overview: Biophysical methods: Exploring structures in motions, from biomolecules to cells, and how to drug them	61
Advances in native cell membrane nanoparticles system	59
Modeling membranes in situ	59
Dynamics and interactions of intrinsically disordered proteins	59
The mannose receptor ligands and the macrophage glycome	58
Markov field models: Scaling molecular kinetics approaches to large molecular machines	56
Advancing protein structure prediction beyond AlphaFold2	56
Implications of disease-related mutations at protein–protein interfaces	54
Principles of nucleosome recognition by chromatin factors and enzymes	52
Conformational penalties: New insights into nucleic acid recognition	52
Proteins with alternative folds reveal blind spots in AlphaFold-based protein structure prediction	52
Deep learning for intrinsically disordered proteins: From improved predictions to deciphering conformational ensembles	49
Mutually beneficial confluence of structure-based modeling of protein dynamics and machine learning methods	48
Probing protein–DNA interactions and compaction in nanochannels	47
Challenges and compromises: Predicting unbound antibody structures with deep learning	46
CryoEM of V-ATPases: Assembly, disassembly, and inhibition	44
Biomolecular simulations at the exascale: From drug design to organelles and beyond	44
Artificial intelligence in therapeutic antibody design: Advances and future prospects	44
The role of RNA structure in 3’ end processing in eukaryotes	44
Microsecond time-resolved cryo-electron microscopy	44