Anti-Cancer Drugs

Article	Citations
Effect of berbamine on invasion and metastasis of human liver cancer SMMC-7721 cells and its possible mechanism	56
Rapid and durable response to fifth-line lorlatinib plus olaparib in an ALK-rearranged, BRCA2-mutated metastatic lung adenocarcinoma patient with critical tracheal stenosis: a case report	52
Circ_0003998 upregulates ARK5 expression to elevate 5-Fluorouracil resistance in hepatocellular carcinoma through binding to miR-513a-5p	24
A retrospective assessment of real-world experience with venetoclax and azacitidine therapy in elderly acute myeloid leukemia	23
BTK inhibitors enhance NKG2D ligand expression by regulating IL-10/STAT3 pathway in activated non-GCB diffuse large B-cell lymphoma cells	22
Hypoxia-inducible factor-1α inhibition augments efficacy of programmed cell death 1 antibody in murine prostatic cancer models	20
FV-429 suppresses cancer cell migration and invasion by EMT via the Hippo/YAP1 pathway in pancreatic cancer cells	20
YKL-06-061 exerts antitumor effect through G1/S phase arrest by downregulating c-Myc and inhibition of metastasis via SIK1 upregulation in pancreatic cancer	20
WISP1 inhibition of YAP phosphorylation drives breast cancer growth and chemoresistance via TEAD4 activation	19
Interferon-α1b for the treatment of metastatic melanoma: results of a retrospective study	19
CircRNA B cell linker regulates cisplatin sensitivity in nonsmall cell lung cancer via microRNA-25-3p/BarH‑like homeobox 2 axis	18
Pyrotinib treatment enhances the radiosensitivity in HER2-positive brain metastatic breast cancer patients	18
Circular RNA circ_0073181 contributes to tumorigenesis by regulating protein tyrosine phosphatase receptor type E via miR-548p in hepatocellular carcinoma	18
Complete response of recurrent perihilar cholangiocarcinoma following sintilimab combined with lenvatinib plus S-1: a case report and review of literature	17
Acquired EML4-ALK fusion and EGFR C797S in cis mutation as resistance mechanisms to osimertinib in a non-small cell lung cancer patient with EGFR L858R/T790M	16
Aumolertinib-based comprehensive treatment for an uncommon site of EGFR exon 20 insertion mutations with multiple metastases non-small cell lung cancer: a case report	16
Partial response of metastatic cardia neuroendocrine carcinoma with the combined therapy involving PD-1 blockade after failed multi-line chemotherapies: a case report and literature review	16
Knockdown of circLRWD1 weakens DDP resistance via reduction of SIRT5 expression through releasing miR-507 in non-small cell lung cancer	16
Nivolumab combined docetaxel versus nivolumab in patients with previously treated nonsmall cell lung cancer: a phase 2 study	15
Interference with PLA2G16 promotes cell cycle arrest and apoptosis and inhibits the reprogramming of glucose metabolism in multiple myeloma cells by modulating the Hippo/YAP signaling pathway	15
Novel dibenzoylmethane derivative 2-allyl-1,3-diphenyl-1,3-propanedione: a safe and effective topical treatment for melanoma	14
The prolonged clinical benefit with metronomic chemotherapy (VEX regimen) in metastatic breast cancer patients	14
Computational study of novel natural inhibitors targeting Kirsten rat sarcoma viral oncogene homolog G12C	14
LncRNA FOXP4-AS1 silencing inhibits metastasis and epithelial–mesenchymal transition in nasopharyngeal carcinoma via miR-136-5p/MAPK1	14
APLNR promotes the progression of osteosarcoma by stimulating cell proliferation and invasion: Retraction	14

Afatinib in the treatment of brain metastases of lung cancer with one rare EGFR mutation: a two-case report	14
Anoikis-related lncRNA signature predicts prognosis and is associated with immune infiltration in hepatocellular carcinoma	14
Anticancer properties of novel zinc oxide quantum dot nanoparticles against breast cancer stem-like cells	14
Neutrophil-to-lymphocyte ratio predicts therapy outcomes of transarterial chemoembolization combined with tyrosine kinase inhibitors plus programmed cell death ligand 1 antibody for unresectable hepat	14
HER2-positive advanced biliary tract cancer responds to second-line pyrotinib therapy: a case report	13
Circular RNA circ_0000592 elevates ANXA4 expression via sponging miR-1179 to facilitate tumor progression in gastric cancer	13
Real-world efficacy and safety of lorlatinib in treating advanced ALK-positive non–small cell lung cancer patients	13
Transcription factor ZEB1 regulates PLK1-mediated SKA3 phosphorylation to promote lung cancer cell proliferation, migration and cell cycle	13
Bevacizumab and anexelekto inhibitor, TP-0903 inhibits TGF-β1-induced epithelial–mesenchymal transition of colon cancer cells	13
Circ_0005615 contributes to the progression and Bortezomib resistance of multiple myeloma by sponging miR-185-5p and upregulating IRF4	12
M2 tumor-associated macrophage promoted DNA methylation in lung cancer metastasis via intensifying EZH2	12
Real-life data on adjuvant trastuzumab emtansine treatment in early-stage HER2-positive breast cancer: a Turkish Oncology Group study	12
Remarkable response to gemcitabine rechallenge in advanced urothelial carcinoma: a case report	12
Identification of exosomal circRNA CD226 as a potent driver of nonsmall cell lung cancer through miR-1224-3p/high mobility group AT-hook 2 axis	12
Downregulation of RPS14 inhibits the proliferation and metastasis of estrogen receptor-positive breast cancer cells	12
Venetoclax-induced vitiligo in a patient with chronic lymphocytic leukemia	12
TRIM11 expression levels was downregulated and prevents ferroptosis of cardiomyocyte by Dusp6 in acute myocardial infarction	12
α-Asarone attenuates tumor-associated macrophages-induced gemcitabine resistance in pancreatic carcinoma via the transforming growth factor-beta 1/growth factor independent 1 axis	11
Electrochemotherapy with bleomycin as an effective local treatment for Kaposi’s sarcoma: a case report	11
Successful immunotherapy with PD-1 Iinhibitor for advanced pancreatic cancer: report of two cases and review of literature	11
A case of diabetic ketoacidosis triggered by immune checkpoint inhibitors in the treatment of recurrent nasopharyngeal carcinoma	11
Epidermal growth factor receptor mutation p.A864V in small cell lung cancer and lung squamous cell carcinoma: a case report and review of literature	11
Tislelizumab plus chemotherapy is an optimal option for second-line treatment for advanced gastroesophageal junction adenocarcinoma	11
Multimodal treatment with cisplatin for metastatic disease in malignant peripheral nerve sheath tumors: a case report and review	11
MiR-30a-5p/CHD1 axis enhances cisplatin sensitivity of ovarian cancer cells via inactivating the Wnt/β-catenin pathway	11
DNA methyltransferase inhibitor 5-azacytidine enhances neuroblastoma cell lysis by an oncolytic parainfluenza virus	11
Evaluation of nuclear PGAM2 value in hepatocellular carcinoma prognosis	10
ZNF668: a new diagnostic predictor of kidney renal clear cell carcinoma	10
Circ_0009035 regulates the progression of cervical cancer by targeting miR-1305/CREBRF axis	10
miR-26b-5p suppresses chemoresistance in breast cancer by targeting serglycin	10
Pazopanib-induced chylothorax in a patient with renal cell carcinoma	10
Impact of KMN network genes on progression and prognosis of non-small cell lung cancer	10
Anlotinib is effective in the treatment of advanced pancreatic cancer: a case report	10
Osimertinib is an effective epidermal growth factor receptor-tyrosine kinase inhibitor choice for lung cancer with epidermal growth factor receptor exon 18–25 kinase domain duplication: report of two	10
Anlotinib for the treatment of pulmonary epithelioid inflammatory myofibroblastic sarcoma: a case report	9
Successful treatment with lenvatinib in a patient with thymic carcinoma presenting with cardiac tamponade: a case report and review of literature	9
Identifying predictive biomarkers of apatinib in third-line treatment of advanced colorectal cancer through comprehensive genomic profiling	9
Intravenous immunoglobulin efficacy on pembrolizumab induced severe toxic epidermal necrolysis	9
Circ_0085495 knockdown reduces adriamycin resistance in breast cancer through miR-873-5p/integrin β1 axis	9
Nivolumab- and ipilimumab-induced myositis, myasthenia gravis, and myocarditis in a patient with metastatic melanoma	9
Salvage chemotherapy in patients with nonsmall cell lung cancer after prior immunotherapy: a retrospective, real-life experience study	9
Complete response with trastuzumab in heavily pretreated HER2-positive metastatic salivary duct carcinoma	9
Effect of statins use on risk and prognosis of breast cancer: a meta-analysis	9
Differential functionality of fluoropyrimidine nucleosides for safe cancer therapy	9
Analysis of clinical factors associated with survival in patients with soft-tissue sarcoma receiving trabectedin	9
CircSETDB1 contributes to paclitaxel resistance of ovarian cancer cells by sponging miR-508-3p and regulating ABCC1 expression	9
Biodegradable controlled-release polymer containing butylidenephthalide to treat a recurrent cervical spine glioblastoma with promising result: a compassionate trial report	9
Rare anti-VEGFR therapy-induced toxicity and long-term response to immunotherapy in a rare non-clear cell renal cell carcinoma patient	9
Circ_0001658 regulates gefitinib resistance of non-small cell lung cancer through miR-409-3p/TWIST1 axis	9
Immunotherapy combined with chemotherapy in the treatment for rare primary mucoepidermoid carcinoma of the liver: a case report	8

HMOX1 regulates ferroptosis via mic14 and its impact on chemotherapy resistance in small-cell lung cancer	8
Transcriptional regulation of CYR61 and CTGF by LM98: a synthetic YAP-TEAD inhibitor that targets in-vitro vasculogenic mimicry in glioblastoma cells	8
Diagnostic and prognostic value of serum soluble B7-H3 in nonsmall cell lung cancer	8
Lidocaine hampers colorectal cancer process via circITFG2/miR-1204/SOCS2 axis	8
Blocking circ_0010235 suppresses acquired paclitaxel resistance of non-small cell lung cancer by sponging miR-512-5p to modulate FAM83F expression	8
Complete response to first-line osimertinib monotherapy in a complex epidermal growth factor receptor mutant (L833V/H835L) lung adenocarcinoma patient: a case report	8
Berberine inhibits prostate cancer progression by inducing ferroptosis: evidence from network pharmacology	8
Extended survival in a case of metastatic choroidal melanoma with immunotherapy	8
Apoptotic and autophagic cell death induced in cervical cancer cells by a dual specific oncolytic adenovirus	8
Ado-trastuzumab emtansine in the treatment of lung adenocarcinoma with ERBB2 mutation: a case report and literature review	8
Pyrotinib for HER2-amplified non-small cell lung cancer patient after progression to Afatinib: a case report	8
Clinical and radiological evaluation of a phyllodes tumor of the breast: a case report	8
CDKN2A inhibited ferroptosis through activating JAK2/STAT3 pathway to modulate cisplatin resistance in cervical squamous cell carcinoma	8
A late relapse thymoma and pure red cell aplasia case with an over 5 years of clinical response under everolimus	8
Potential mechanism of pyrotinib-induced diarrhea was explored by gut microbiome and ileum metabolomics	8
GATA3 positively regulates PAR1 to facilitate in vitro disease progression and decrease cisplatin sensitivity in neuroblastoma via inhibiting the hippo pathway	7
What management for epidermal growth factor receptor-mutated non–small-cell lung cancer, with squamous cell transformation and T790M-acquired resistance mechanisms? A Case report and review of literat	7
Norcantharidin counteracts acquired everolimus resistance in renal cell carcinoma by dual inhibition of mammalian target of rapamycin complex 1 and complex 2 pathways in Vitro	7
Mechanism of gemcitabine combined with lobaplatin in interventional treatment of locally advanced cervical cancer	7
Azacitidine combined with venetoclax alleviates AML-MR with TP53 mutation in SDS: a case report and literature review	7
Concurrent NRAS-BRAF variants in metastatic colorectal cancer: a Tunisian case report	7
Mucinous appendiceal adenocarcinoma invading the bladder: not always an easy diagnosis. A case report	7
Long-term survival of an ALK fusion lung adenocarcinoma patient with high mutation burden and microsatellite instability high: a case report	7
Hemodialysis requirement after the first dose of durvalumab following chemoradiation therapy: a case report	7
AZD7762 induces CRBN dependent BAG3 degradation through ubiquitin-proteasome pathway	7
Pulmonary toxicity following administration of granulocyte colony-stimulating factor during chemotherapy for breast cancer: a case report and literature review	7
A meta-analysis of the effect and safety of platinum-based neoadjuvant chemotherapy in treatment of resectable triple-negative breast cancer	7
Exosomal miR-93-5p from cancer-associated fibroblasts confers malignant phenotypes on bladder cancer cells by targeting PAFAH1B1	7
Circ_0027089 regulates NACC1 by targeting miR-136-5p to aggravate the development of hepatitis B virus-related hepatocellular carcinoma	7
Utidelone plus pembrolizumab as the fourth-line combination treatment in non-small cell lung cancer with EGFR mutation: a case report	7
Efficacy and safety of sintilimab combined with apatinib as third-line or above therapy for patients with advanced or metastatic gastric cancer	7
Expression and clinical significance of CXCL17 and GPR35 in endometrial carcinoma	7
Kruppel-like factor 5 enhances proliferation, lipid droplet formation and oxaliplatin resistance in colorectal cancer by promoting fatty acid binding protein 6 transcription	7
MiR-302c-5p affects the stemness and cisplatin resistance of nasopharyngeal carcinoma cells by regulating HSP90AA1	7
CircFOXM1 silencing represses cell proliferation, migration and invasion by regulating miR-515-5p/ADAM10 axis in prostate cancer	7
Stewart-Treves syndrome in an older woman successfully treated by metronomic chemotherapy: case report and literature survey	7
Response to olaparib in metastatic lung adenocarcinoma with germline BRCA2 mutation: a case report	7
M2 macrophage-derived exosomal miR-1911-5p promotes cell migration and invasion in lung adenocarcinoma by down-regulating CELF2-activated ZBTB4 expression	7
Immunotherapy rechallenge of advanced lung adenocarcinoma with cadonilimab (PD-1/CTLA-4 Bi-specific antibody): a case report	7
Reuse of osimertinib after small cell lung cancer transformation in lung adenocarcinoma with de-novo epidermal growth factor receptor T790M mutation: case report	7
Hyper-late major response after 5 years of nivolumab: role of treatment beyond progression in head and neck cancer	6
A dual thermo/pH-sensitive hydrogel as 5-Fluorouracil carrier for breast cancer treatment	6
Pretreatment platelet-to-lymphocyte ratio and neutrophil-to-lymphocyte ratio as a predictor of pathological complete response to neoadjuvant chemotherapy in patients with breast cancer: single center	6
Metastatic small cell lung cancer – an aggressive disease: a case report and literature review	6
Successful treatment of severe lung cancer caused by third-generation EGFR-TKI resistance due to EGFR genotype conversion with afatinib plus anlotinib	6
Inhibition of MNK pathway sensitizes nasopharyngeal carcinoma to radiotherapy	6
USP3 promotes cisplatin resistance in non-small cell lung cancer cells by suppressing ACOT7-regulated ferroptosis	6
Asynchrony of primary tumor and mediastinal lymph nodes response after neoadjuvant immunotherapy plus chemotherapy in a patient with stage IIIA non–small-cell lung cancer: a case report	6
Response to erlotinib and bevacizumab combination therapy after acquired resistance to osimertinib in patients with non-small cell lung cancer	6
DEPDC1 affects autophagy-dependent glycolysis levels in human osteosarcoma cells by modulating RAS/ERK signaling through TTK	6
Long-chain noncoding ribonucleic acids affect the survival and prognosis of patients with esophageal adenocarcinoma through the autophagy pathway: construction of a prognostic model	6
GZ17-6.02 interacts with carboplatin and etoposide to kill neuroblastoma cells	6
Pathological complete response achieved with FLOT chemotherapy in two patients with MSI-H esophagogastric junction and gastric adenocarcinoma	6
A meta-analysis on overall survival and safety outcomes in patients with nonmetastatic castration-resistant prostate cancer treated with novel hormonal agents	6
First-line crizotinib therapy is effective for a novel SEC31A-anaplastic lymphoma kinase fusion in a patient with stage IV lung adenocarcinoma: a case report and literature reviews	6
Effect of metformin use on the risk and prognosis of colorectal cancer in diabetes mellitus: a meta-analysis	6
Reply to: Association between nilotinib-induced hyperbilirubinemia and UGT1A1 polymorphisms in a chronic myeloid leukemia patient	6
Therapeutic effects of vitamin D and IL-22 on methotrexate-induced mucositis in mice	6
Dexmedetomidine disrupts esophagus cancer tumorigenesis by modulating circ_0003340/miR-198/HMGA2 axis	6
Comparison of effects of tamoxifen and Toremifene on hepatic function and serum lipids in breast cancer patients during adjuvant endocrine therapy	6
Exosomal circ_0007385 enhances non-small cell lung cancer cell proliferation and stemness via regulating miR-1253/FAM83A axis	6
Exploring the repurposing potential of telmisartan drug in breast cancer: an in-silico and in-vitro approach	6
Antineoplastic activity of GP-2250 in-vitro and in mouse xenograft models	6
Chemoimmunotherapy after progression on single-agent pembrolizumab for metastatic urothelial carcinoma: a case series	6
A case of lung adenocarcinoma with MET∆ex14 mutation regressed after preoperative treatment with savolitinib, and successfully underwent radical resection	6
LncRNA PCAT6 activated by SP1 facilitates the progression of breast cancer by the miR-326/LRRC8E axis	6
Combating anoikis resistance: bioactive compounds transforming prostate cancer therapy	6
Long-term extracranial metastatic relapse of an intraventricular solitary fibrous tumor: a case report	6
First case report of sunvozertinib for the treatment of HER2 exon 20 insertion in lung adenocarcinoma	6
Risk-tailored treatment of splenic marginal zone lymphoma	5
Combined protein and transcriptomics identifies DCTPP1 as a putative biomarkers for predicting immunotherapy responsiveness in gastric cancer patients	5
Association between SLCO1B1 polymorphism and methotrexate-induced hepatotoxicity: a systematic review and meta-analysis	5
The mechanism of circ-PIP5K1A/miR-942-5p/NFIB axis in cisplatin resistance in ovarian cancer based on imaging and molecular diagnosis	5
Unexpected response to fourth-line paclitaxel in a patient with metastatic oropharyngeal squamous cell carcinoma, immunotherapy-refractory: a case report	5
LMCD1 antisense RNA 1 is a newly identified long noncoding RNA	5
LncRNA SNHG11 enhances bevacizumab resistance in colorectal cancer by mediating miR-1207-5p/ABCC1 axis	5
Key considerations when using the sulforhodamine B assay for screening novel anticancer agents	5
The efficacy and safety of adding anlotinib in gradual progression on third-generation EGFR-TKIs for EGFR-mutant advanced nonsmall cell lung cancer	5
Effect of GADD45G on the radioresistance of nasopharyngeal carcinoma cells	5
Efficacy and safety of anlotinib as maintenance therapy after induction chemotherapy in extensive-stage small-cell lung cancer	5

Design of potential anti-cancer agents as COX-2 inhibitors, using 3D-QSAR modeling, molecular docking, oral bioavailability proprieties, and molecular dynamics simulation: Erratum	5
Research on the mechanism of eugenol in the treatment of liver cancer based on network pharmacology, molecular docking technology, and in vitro experiments	5
A review of research progress on mechanisms and overcoming strategies of acquired osimertinib resistance	5
Propranolol suppresses infantile hemangioma cell proliferation and promotes apoptosis by upregulating miR-125b expression: Retraction	5
In regard to Cabezas-Camarero et al.	5
Rapid radiological response of leptomeningeal carcinosis and prolonged survival to encorafenib and binimetinib in BRAF-mutated melanoma	5
Immune checkpoint inhibitors for RET fusion non-small cell lung cancer: hopes and challenges	5
Neoadjuvant alectinib in locally advanced lung adenocarcinoma with anaplastic lymphoma kinase rearrangement: case series and literature review	5
LncRNA MSC-AS1, as an oncogene in melanoma, promotes the proliferation and glutaminolysis by regulating the miR-330-3p/YAP1 axis	5
Immune-checkpoint inhibitors in pituitary malignancies	5
The prognostic values of prognostic nutritional index in extensive-stage small-cell lung cancer	5
A case report of a lung cancer patient with two uncommon EGFR mutations and a review of the literature: two sides of the same coin	5
Stat3 shRNA delivery with folate receptor-modified multi-functionalized graphene oxide particles for combined infrared radiation and gene therapy in hepatocellular carcinoma	5
Methyltransferase-like 3 enhances cell proliferation and cisplatin resistance in natural killer/T-cell lymphoma through promoting N6-methyladenosine modification and the stability of staphylococcal nu	5
Natural products inducing nucleolar stress: implications in cancer therapy	5
Circ_0039569 contributes to the paclitaxel resistance of endometrial cancer via targeting miR-1271-5p/PHF6 pathway	5
Long-term response to immuno-oncology after discontinuation for immuno-related pneumonia in metastatic renal carcinoma: a case report	5
Anti-androgen for myoepithelial tumor: a potent therapy yet a potential misleader	5
Jackfruit waste: an invented anticancer therapy using Jacalin lectin from jackfruit seed	5
Hypotension from afatinib in epidermal growth factor receptor-mutated non-small cell lung cancer: a case report and literature review	5
Efficacy of disitamab vedotin (RC48) for previously treated human epidermal growth factor receptor 2–positive breast cancer with symptomatic brain metastases: a case report and review of the literatur	5
Does bevacizumab carry a hope for metastatic triple-negative breast cancer in the era of immunotherapy?	5
BAP1 loss confers sensitivity to bromodomain and extra-terminal inhibitors in renal cell carcinoma	5
Circ_0058063 promotes progression of thyroid cancer by sponging miR-330-3p/SDC4 axis	5