Human & Experimental Toxicology

Papers
(The median citation count of Human & Experimental Toxicology is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)
ArticleCitations
Silencing lncRNA HCG18 regulates GPX4-inhibited ferroptosis by adsorbing miR-450b-5p to avert sorafenib resistance in hepatocellular carcinoma71
LINC00641 impeded the malignant biological behaviors of papillary thyroid carcinoma cells via interacting with IGF2BP1 to reduce GLI1 mRNA stability49
Sevoflurane preconditioning attenuates myocardial cell damage caused by hypoxia and reoxygenation via regulating the NORAD/miR-144-3p axis46
Silver nanoparticles trigger delayed inflammatory responses in mast cells45
Exploring the utility of zinc finger protein-related genes in predicting hepatocellular carcinoma prognosis, immune responses, and drug efficacy32
Prenatal and early life lead exposure induced neurotoxicity32
Retraction Notice: “Sulforaphane triggers iron overload-mediated ferroptosis in gastric carcinoma cells by activating the PI3K/IRP2/DMT1 pathway”30
Effects of doxorubicin on autophagy in fibroblasts28
Human health risk assessment of heavy metals in different compartments of vegetables from Erbil City-Iraq25
Oxidative stress reactions in rats with pulmonary injuries induced by sulfur mustard (1 LD 50 )22
Development and validation of a novel poisoning agitation-sedation score for predicting the need for endotracheal intubation and mechanical ventilation in acutely poisoned patients with disturbed cons22
LINC00294/miR-620/MKRN2 axis provides biomarkers and negatively regulates malignant progression in colorectal carcinoma21
Retraction Notice20
Effects of polycyclic aromatic hydrocarbon exposure on mitochondrial DNA copy number20
Hyperoside exerts protective effects against anticardiolipin antibody-induced recurrent pregnancy loss in vivo and in vitro20
Effects of methylphenidate on femoral bone growth in male rats20
Acriflavine protects against LPS-induced sepsis via regulation of pyroptosis, inflammation, and endoplasmic reticulum stress20
A new 1,4-dihydropyridine-based L-/T-type calcium channel inhibitor, provides in- vivo and silico cardioprotective effects in doxorubicin toxicity in rat19
Neurodevelopmental toxicity induced by PM2.5 Exposure and its possible role in Neurodegenerative and mental disorders19
Clinical characteristics and the risk factors analysis in patients with delayed encephalopathy after acute carbon monoxide poisoning18
RETRACTED: Ginsenoside Rg5 induces NSCLC cell apoptosis and autophagy through PI3K/Akt/mTOR signaling pathway18
Salidroside attenuates LPS-induced kidney injury through activation of SIRT1/Nrf2 pathway18
Relationship between clock gene expression and CYP2C19 and CYP3A4 with benzodiazepines17
Exosomes derived from M2 macrophages promote fibroblast autophagy to contribute to hypertrophic scar formation via CXCL2/CXCR7/mTOR pathway17
Retraction notice: “3,4-Methylenedioxymethamphetamine causes retinal damage in C57BL/6J mice”16
TLR4/ MyD88/NF-κB signaling pathway involved in the protective effect of diacerein against lung fibrosis in rats16
RETRACTED: Retrospective analysis of the etiology and drugs for vitreous hemorrhage caused by non-diabetic retinopathy and non-traumatic factors15
RETRACTED: CircRNA_001373 promotes liver fibrosis by regulating autophagy activation in hepatic stellate cells via the miR-142a-5p/Becn1 axis15
RETRACTED: Baicalein exerts beneficial effects in lipopolysaccharide-induced pulmonary inflammation by modulating macrophage polarization and inhibiting pyroptosis14
The possible cytotoxicity and genotoxicity assessment of indaziflam on HepG2 cells14
Activation of SIRT3/AMPK/mTOR-mediated autophagy promotes quercetin-induced ferroptosis in oral squamous cell carcinoma13
Cysteine-rich 61(CYR61) alleviates cyclophosphamide-induced proliferation inhibition in ovarian granulosa cells via suppressing NLRP3/caspase1-mediated p13
Protective effects of butylated hydroxytoluene on the initiation of N-nitrosodiethylamine-induced hepatocellular carcinoma in albino rats13
Anlotinib induces apoptosis and second growth/mitosis phase block in cisplatin-resistant ovarian cancer cells via the aurora kinase A/p53 pathway13
MiR-3612 targeting THBS1 suppresses nasopharyngeal carcinoma progression by PI3K/AKT signaling pathway13
Retraction Notice: Association of miR-9-5p and NFIC in the progression of gastric cancer12
RETRACTED: Carvedilol alleviates the detrimental effects of azathioprine on hepatic tissues in experimental rats: Focusing on redox system, inflammatory and apoptosis pathways12
Stevioside inhibits colorectal cancer progression by regulating macrophage polarization12
Retraction notice: “Long noncoding RNA SNHG14 regulates ox-LDL-induced atherosclerosis cell proliferation and apoptosis by targeting miR-186-5p/WIPF2 axis”11
Neuroinflammatory chemokine networks in transgenic models of Alzheimer’s disease: A comparative multi-compartmental analysis11
Correction to “Corrigendum to effect of grape seed extract ondoxorubicin-induced testicular andepididymal damage in rats”11
The effect of melatonin on capecitabine-induced hepatic and renal toxicity in rats11
Assessment of safety through mutagenicity and subchronic toxicity studies with black pepper extract preparation10
Cigarette smoking extract induces mitochondrial dysfunction and apoptosis in HUVECs via the Sirt1-SHH axis10
Anti-oxidative properties of nanocrocin in Zearalenone induced toxicity on Hek293 cell; The novel formulation and cellular assessment10
MAPK-interacting kinases inhibition by eFT508 overcomes chemoresistance in preclinical model of osteosarcoma9
Diagnostic and prognostic value of diquat plasma concentration and complete blood count in patients with acute diquat poisoning based on random forest algorithms9
SEMA3C regulates tumor-associated macrophage phenotype and influences lung cancer cell migration and invasion through VNN19
Persistent diazinon induced neurotoxicity: The effect on inhibitory avoidance memory performance, amyloid precursor proteins, and TNF-α levels in the prefrontal cortex of rats9
Establishment of a rat model of bronchopulmonary dysplasia complicated with pulmonary hypertension and its potential applications9
A review of challenges and prospects of 3D cell-based culture models used for studying drug induced liver injury during early phases of drug development9
Trimethylamine-N oxide enhances post-stroke depression progression via ROS-p38/MAPK signaling9
Down-regulation of E2F1 attenuates UVB-induced human lens epithelial cell oxidative stress and pyroptosis through inhibiting NLRP39
Protective effects of brain and muscle ARNT-like gene 1 on oxidized low-density lipoprotein-induced human brain microvascular endothelial cell injury by alleviating ferroptosis8
RETRACTED: Downregulation of miR-138-5p alleviates propofol-induced neurotoxicity and autophagy by regulating SIRT18
Increased FGFR3 is involved in T-2 toxin-induced lesions of hypertrophic cartilage associated with endemic osteoarthritis8
Evaluation of the effectiveness of fresh frozen plasma transfusion as adjuvant treatment in acute organophosphate-poisoned patients: A randomized clinical trial8
Environmental contaminants, endocrine disruption, and transgender: Can “born that way” in some cases be toxicologically real?8
Clinical utility of combined butyrylcholinesterase activity measurements in assessing acute malathion intoxication severity: A case series8
Retraction Notice: “YTHDF1-mediated sphingosine kinase 2 upregulation alleviates bupivacaine-induced neurotoxicity via the PI3K/AKT axis”7
Tricin attenuates diabetic retinopathy by inhibiting oxidative stress and angiogenesis through regulating Sestrin2/Nrf2 signaling7
Renal glucose transporters play a role in removal of cadmium from kidney cells mediated by GMDTC – A novel metal chelator7
Hypoxia-induced autophagy attenuates ferredoxin 1-mediated cuproptosis in colorectal cancer cells7
Retraction: Protection by pentoxifylline of malathion-induced toxic stress and mitochondrial damage in rat brain7
A new bayesian framework for dose-response modelling and benchmark dose determination7
Emodin protects against apoptosis and inflammation by regulating reactive oxygen species-mediated NF- κ B signaling in interleukin‐1 7
Omarigliptin/shikonin combination alleviates cyclosporine-induced nephrotoxicity: The role of sirtuin 1, glucagon-like peptide-1, HMGB1/RAGE/TLR4 signaling, and p38/ERK/JNK MAPKs7
Discovering the most impactful treatments for aluminum phosphide cardiotoxicity gleaned from systematic review of animal studies7
RETRACTED: Ginsenoside Re suppresses high glucose-induced apoptosis of placental trophoblasts through endoplasmic reticulum stress-related CHOP/GADD1537
RETRACTED: Sulforaphane triggers iron overload-mediated ferroptosis in gastric carcinoma cells by activating the PI3K/IRP2/DMT1 pathway7
Anti-EMT properties of ergothioneine attenuate lipopolysaccharide-induced oxidative stress-mediated acute lung injury via modulating TGF-β/smad/snail signaling pathway7
Nickel; a metal with threats to human health, focusing on its intoxication mechanisms7
Alleviation of the mitochondrial dynamics impairment in doxorubicin-induced cardiomyocyte toxicity by cardioprotective agents7
Retraction Notice7
Retraction Notice6
CircKRT14 upregulates E2F3 by interacting with miR-1256 to act as an oncogenic factor in esophageal cancer6
Corrigendum to “Apoptosis-promoting and migration-suppressing effect of alantolactone on gastric cancer cell lines BGC-823 and SGC-7901 via regulating p38MAPK and NF-κB pathways”6
Ozone in the adjunct medical treatment. The round personality of a molecule with hormetic properties6
Subchronic inhalation of a novel electronic nicotine delivery system formulation and its corresponding base formulation6
Neurologic disease produced by Rathayibacter toxicus -derived corynetoxins6
Cathepsin B mediates the lysosomal-mitochondrial apoptosis pathway in arsenic-induced microglial cell injury6
RNA-seq analysis revealed genes associated with neuropathic pain induced by chronic compressive injury in interferon regulatory factors 4 knockout mice6
Rhamnazin ameliorates 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin-evoked testicular toxicity by restoring biochemical, spermatogenic and histological profile in male albino rats6
Nomogram for predicting mechanical ventilation need among acutely intoxicated patients with impaired consciousness: Correspondence6
Establishment of an animal model of sciatic nerve injury induced by local anesthetics6
Corrigendum to “Diagnostic and prognostic value of diquat plasma concentration and complete blood count in patients with acute diquat poisoning based on random forest algorithms”6
Evaluation of Cd-induced cytotoxicity in primary human keratinocytes6
Curculigoside attenuates cerebral ischemia-reperfusion injury via TRPM2-mediated microglial polarization5
High-dose vitamin C potently induces apoptosis in acute lymphoblastic leukemia by activating ER stress response5
Retraction Notice5
Stereotactic body radiation therapy suppresses myeloid-derived suppressor cells by regulating miR-21/Sorbin and SH3 Domain-containing Protein 1 axis5
RETRACTED: Arsenic-induced downregulation of BRWD3 suppresses proliferation and induces apoptosis in lung adenocarcinoma cells through the p53 and p65 pathways5
Ginkgolide A downregulates transient receptor potential (melastatin) 2 to protect cisplatin-induced acute kidney injury in rats through the TWEAK/Fn14 pathway: Ginkgolide A improve acute renal injury5
The effects of esketamine on the intestinal microenvironment and intestinal microbiota in mice5
Dexmedetomidine and propofol-induced neurotoxicity: Promise, but caution warranted5
Water-soluble Yb 3+ , Er 3+ codoped NaYF 4 nano5
Potential induction of h yperkeratosis in r ats’ c ervi 5
Mechanism of triiodothyronine alleviating acute alcoholic liver injury and delaying alcoholic liver fibrosis progression5
Circ_0000285 regulates nasopharyngeal carcinoma progression through miR-1278/FNDC3B axis5
Clinical and laboratory prognostic factors associated with methanol toxicity outcomes in patients at Tabriz Sina Hospital: A retrospective study5
Alkylating agents are possible inducers of glioblastoma and other brain tumors5
Targeted inhibition of STING-TBK1 axis alleviates the hepatotoxicity of tripterygium glycosides5
KLF9 mediates NLRP3 inflammasome and reactive oxygen species to mediate pyroptosis in trophoblasts5
Hepatoprotective potential of diosmin against hepatotoxic effect of isoniazid and rifampin in wistar rats5
Integrated gut microbiota and serum metabolomics reveal glyphosate-induced hepatic injury in mice5
Nrf2 attenuates methamphetamine-induced myocardial injury by regulating oxidative stress and apoptosis in mice4
An artificial intelligence algorithm for analyzing globus pallidus necrosis after carbon monoxide intoxication4
Impact of combined chronic exposure to low-dose bisphenol A and fructose on serum adipocytokines and the energy target metabolome in white adipose tissue4
The acute and sub-chronic toxicological effects of 3-amino-9-ethylcarbazole (AEC) on zebrafish4
Effects of combined exposure of manganese and iron on serum inflammatory factor levels among workers4
Conflicts of interest in the International Agency for Research on Cancer process of identifying carcinogenic hazards to humans4
Preclinical Evaluation of interferon-gamma primed human Wharton’s jelly-derived mesenchymal stem cells4
Retraction: Ginsenoside re suppresses high glucose-induced apoptosis of placental trophoblasts through endoplasmic reticulum stress-related CHOP/GADD1534
Pelargonidin-3-O-glucoside prevents isoproterenol-induced myocardial infarction via modulating cardiac and inflammatory markers expression in experimental rats4
Effect of grape seed extract on doxorubicin-induced testicular and epididymal damage in rats4
MG132 inhibits proliferation and induces apoptosis of acute lymphoblastic leukemia via Akt/FOXO3a/Bim pathway4
Physalin A induces apoptosis through conjugating with Fas-FADD cell death receptor in human oral squamous carcinoma cells and suppresses HSC-3 cell xenograft tumors in NOD/SCID mice4
Retraction Notice4
Protocatechuic acid mitigates 5-fluorouracil-triggered renal and hepatic injury in rats4
Histological and immunohistochemical alterations in the brain tissues induced by the subchronic toxicity of gold nanoparticles: In vivo study4
Retraction Notice4
Insights into therapeutic potential and practical applications of natural toxins from poisonous mushrooms4
Comparing the effectiveness of L-carnitine and paraffin oil in acute aluminum phosphide poisoning using predictive biomarkers and scores: A randomized controlled clinical trial4
Punicalagin is cytotoxic to human colon cancer cells by modulating cell proliferation, apoptosis, and invasion4
RETRACTED: Comparative analysis of noise and music exposure on inflammatory responses on lipopolysaccharide-induced septic rats4
Acrylamide-induced meiotic arrest of spermatocytes in adolescent mice by triggering excessive DNA strand breaks: Potential therapeutic effects of resveratrol4
Wasp-stung rat model translationally expresses the coagulopathy manifestations of human wasp patients4
Association between serum complement 1q and the associated factors of acute ischemic stroke in patients with type 2 diabetes4
Withdrawn—Administrative Error: “Corrigendum to ‘Carvedilol alleviates the detrimental effects of azathioprine on hepatic tissues in experimental rats: Focusing on redox system, inflammatory and apopt4
Problems with the effectiveness of L-carnitine and paraffin oil in acute aluminum phosphide poisoning4
Retraction: Protective effects of casein-derived peptide VLPVPQK against hydrogen peroxide-induced dysfunction and cellular oxidative damage in rat osteoblastic cells4
Development and validation of a nomogram for predicting mechanical ventilation need among acutely intoxicated patients with impaired consciousness4
Ergot alkaloid consumption alters serotonin receptor-induced vasoactivity in ovine umbilical vasculature4
In silico evaluations of phytochemicals from Withania somnifera exhibiting anticancer activity against NAD[P]H-quinone oxidore4
Follow-up of patients with a 5-year survival after paraquat poisoning using computed tomography images and spirometry4
Performance assessment of new Poisoning Mortality Score and PGI score for predicting mortality in patients with acute aluminum phosphide poisoning3
Protective effects of Tribulus Terrestris extract on cisplatin-induced ovarian damage: Antioxidants and anti-inflammatory insights3
Tanshinone I induces ferroptosis in gastric cancer cells via the KDM4D/p53 pathway3
Mechanism of action of curcumin targeting TRPM2/NLRP3 signaling axis to mediate cell death in the treatment of knee osteoarthritis3
Microsomal glutathione S-transferase 1 targets the autophagy signaling pathway to suppress ferroptosis in gastric carcinoma cells3
Relationship between the start time of treatment and patient prognosis in cases of acute wild mushroom poisoning in a certain region of Guizhou Province, China from 2013 to 2020: A retrospective Obser3
Liver and ovarian toxicities boosted by bisphenol and gamma radiation in female albino rats3
Nifuroxazide attenuated 5-fluorouracil-induced cardiac intoxication by regulating NLRP3/STAT-3, PPAR-γ, and apoptosis signals3
Glutathione S-transferase zeta 1 alters the HMGB1/GPX4 axis to drive ferroptosis in bladder cancer cells3
Integrative analysis of renal microRNA and mRNA to identify hub genes and pivotal pathways associated with cyclosporine-induced acute kidney injury in mice3
KLF6 silencing attenuates MCAO-induced brain injury and cognitive dysfunction via targeting ferroptosis and activating the Nrf2/HO-1 pathway3
Predictive factors of severe outcome in glufosinate ammonium poisoning: A retrospective study in Vietnam3
Bardoxolone methyl triggers Ferroptosis in cardiomyocytes3
Assessment of acute and subchronic skin toxicity of drilling fluids3
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