Human & Experimental Toxicology

Papers
(The TQCC of Human & Experimental Toxicology is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)
ArticleCitations
Effects of butein on human osteosarcoma cell proliferation, apoptosis, and autophagy through oxidative stress57
Lipid emulsions attenuate the inhibition of carnitine acylcarnitine translocase induced by toxic doses of local anesthetics in rat cardiomyoblasts49
The role of ferroptosis in organ toxicity40
RETRACTION NOTICE: Curcumin and resveratrol inhibit chemoresistance in cisplatin-resistant epithelial ovarian cancer cells via targeting P13K pathway39
RETRACTED: AgNPs reduce reproductive capability of female mouse for their toxic effects on mouse early embryo development36
Myricetin (3,3′,4′,5,5′,7-hexahydroxyflavone) prevents ethanol-induced biochemical and inflammatory damage in the liver of Wistar rats36
Protective effects of alpha-lipoic acid on bleomycin-induced skin fibrosis through the repression of NADPH Oxidase 4 and TGF-β1/Smad3 signaling pathways35
Assessment of the genotoxic potential of tetrachlorvinphos insecticide by cytokinesis-block micronucleus and sister chromatid exchange assays34
Curcumin alleviated lipopolysaccharide-evoked H9c2 cells damage via suppression of intercellular adhesion molecule 1/CD40/NF-κB signaling31
Prenatal and early life lead exposure induced neurotoxicity30
RETRACTED: Cytochrome P450 3A5 polymorphism affects the metabolism of sorafenib and its toxicity for hepatocellular carcinoma cells in vitro28
Pediatric allergic rhinitis with functional gastrointestinal disease: Associations with the intestinal microbiota and gastrointestinal peptides and therapeutic effects of interventions27
Hepatoprotective potential of diosmin against hepatotoxic effect of isoniazid and rifampin in wistar rats27
Diosgenin inhibits the proliferation of gastric cancer cells via inducing mesoderm posterior 1 down-regulation-mediated alternative reading frame expression27
Corrigendum to “The PAD4 inhibitor GSK484 enhances the radiosensitivity of triple-negative breast cancer”26
RETRACTED: Ginsenoside 20(S)-Rg3 suppresses cell viability in esophageal squamous cell carcinoma via modulating miR-324-5p-targeted PSME324
Assessment of the cellular integrity and expression of melatonin receptor (MTNR1A) in the retina assaulted by ethanol and acetaminophen24
Exposure to pesticides and pediatric Wilms’ tumor. A meta-analysis on pre-conception and pregnancy parental exposure with an IARC/WHO commentary22
Inhibiting p21-activated kinase (PAK7) enhances radiosensitivity in hepatocellular carcinoma22
Developmental toxicity of cryptotanshinone on the early-life stage of zebrafish development21
Hepatic P53 upregulation and the genotoxic potential of acesulfame-K treatment in rats with a special emphasis on in vitro lymphocyte and macrophage activity testing21
Widely targeted quantitative lipidomics reveal lipid remodeling in adipose tissue after long term of the combined exposure to bisphenol A and fructose20
Diagnostic and prognostic value of diquat plasma concentration and complete blood count in patients with acute diquat poisoning based on random forest algorithms20
Effect of taxifolin/dapagliflozin combination on colistin-induced nephrotoxicity in rats19
RETRACTION NOTICE: Effect of nano zinc oxide on proliferation and toxicity of human gingival cells18
Long non-coding RNA LINC00630 facilitates hepatocellular carcinoma progression through recruiting transcription factor E2F1 to up-regulate cyclin-dependent kinase 2 expression18
Syringaresinol inhibits cardiorenal fibrosis through HSP90 in a cardiorenal syndrome type 218
Resolvin D1 protects against cadmium chloride-induced memory loss and hippocampal damage in rats: A comparison with docosahexaenoic acid18
Protective effect of dexmedetomidine on neuronal hypoxic injury through inhibition of miR-13418
Glutathione S-transferase zeta 1 alters the HMGB1/GPX4 axis to drive ferroptosis in bladder cancer cells17
MiR-141 attenuates sepsis-induced cardiomyopathy by targeting DAPK116
Loss of PHLDA1 has a protective role in OGD/R-injured neurons via regulation of the GSK-3β/Nrf2 pathway16
Role of the AMPK signalling pathway in the aetiopathogenesis of ocular diseases16
Anti-oxidative properties of nanocrocin in Zearalenone induced toxicity on Hek293 cell; The novel formulation and cellular assessment16
Rhynchophylline promotes microglia phenotypic transformation and repair of cerebral ischaemic injury through the JAK2/STAT3 pathway15
Retraction Notice15
Wasp-stung rat model translationally expresses the coagulopathy manifestations of human wasp patients15
The effects of esketamine on the intestinal microenvironment and intestinal microbiota in mice15
Corrigendum to “Carvedilol alleviates the detrimental effects of azathioprine on hepatic tissues in experimental rats: Focusing on redox system, inflammatory an15
Synergistic effects of sinapic acid and ellagic acid ameliorate streptozotocin-induced diabetic nephropathy by inhibiting apoptosis, DNA damage, and structural deterioration in rats15
Repurposing Ivermectin to augment chemotherapy’s efficacy in osteosarcoma15
The acute and sub-chronic toxicological effects of 3-amino-9-ethylcarbazole (AEC) on zebrafish15
Assessment of safety through mutagenicity and subchronic toxicity studies with black pepper extract preparation14
Pulmonary toxicity of sodium dichloroisocyanurate after intratracheal instillation in sprague-dawley rats14
Sevoflurane preconditioning attenuates myocardial cell damage caused by hypoxia and reoxygenation via regulating the NORAD/miR-144-3p axis14
Effects of larazotide acetate, a tight junction regulator, on the liver and intestinal damage in acute liver failure in rats14
Anti-inflammatory secondary metabolites from Scrophularia kotschyana14
Alkylating agents are possible inducers of glioblastoma and other brain tumors14
LncRNA colorectal neoplasia differentially expressed exacerbates the impairments in learning and memory induced by isoflurane14
Tanshinone IIA alleviate rifampicin-induced cholestasis by regulating the expression and function of bile salt export pump13
Performance assessment of new Poisoning Mortality Score and PGI score for predicting mortality in patients with acute aluminum phosphide poisoning13
Relationship between the start time of treatment and patient prognosis in cases of acute wild mushroom poisoning in a certain region of Guizhou Province, China from 2013 to 2020: A retrospective Obser13
Can granulocyte colony stimulating factor (G-CSF) ameliorate acetaminophen-induced hepatotoxicity?13
Retraction notice: “Long noncoding RNA SNHG14 regulates ox-LDL-induced atherosclerosis cell proliferation and apoptosis by targeting miR-186-5p/WIPF2 axis”13
Stereotactic body radiation therapy suppresses myeloid-derived suppressor cells by regulating miR-21/Sorbin and SH3 Domain-containing Protein 1 axis13
Gallic acid inhibits celecoxib-induced mitochondrial permeability transition and reduces its toxicity in isolated cardiomyocytes and mitochondria12
Tanshinone I induces ferroptosis in gastric cancer cells via the KDM4D/p53 pathway12
In vitro toxicological assessment of flumethrin’s effects on MCF-7 breast cancer cells12
T-2 toxin induces articular cartilage damage by increasing the expression of MMP-13 via the TGF-β receptor pathway12
ZNF219 protects human lens epithelial cells against H2O2-induced injury via targeting SOX9 through activating AKT/GSK3β pathway12
Effect of thymoquinone on pharmacokinetics of 5-fluorouracil in rats and its effect on human cell line in vitro12
Effects of Achillea tenuifolia Lam. hydro-alcoholic extract on anxiety-like behavior and reproductive parameters in rat model of chronic restraint stress12
Effect of curcumin on the non-alcoholic steatohepatitis via inhibiting the M1 polarization of macrophages12
An artificial intelligence algorithm for analyzing globus pallidus necrosis after carbon monoxide intoxication11
Impact of combined chronic exposure to low-dose bisphenol A and fructose on serum adipocytokines and the energy target metabolome in white adipose tissue11
Corrigendum11
Liver and ovarian toxicities boosted by bisphenol and gamma radiation in female albino rats11
MFGE8 decreased neuronal apoptosis and neuroinflammation to ameliorate early brain injury induced by subarachnoid hemorrhage through the inhibition of HMGB111
Retraction Notice11
KLF6 silencing attenuates MCAO-induced brain injury and cognitive dysfunction via targeting ferroptosis and activating the Nrf2/HO-1 pathway11
Cyclophosphamide inhibits Pax5 methylation to regulate the growth of retinoblastoma via the Notch1 pathway11
The sesquiterpenoid valerenic acid protects neuronal cells from the detrimental effects of the fungicide benomyl on apoptosis and DNA oxidation11
Pedunculoside inhibits cardiomyocyte inflammatory biomarkers via Nrf2/HO-1 pathway in high glucose-induced H9c2 cells and diabetic cardiomyopathy model rats10
Ginsenoside Rk1 prevents 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson’s disease via activating silence information regulator 3-mediated Nrf2/HO-1 signaling pathway10
Mitochondrial dysfunction is involved in the cellular activity inhibition by eleutheroside B in SMMC-7721 and HeLa cells10
Gallic acid protects against isoproterenol-induced cardiotoxicity in rats10
Neutrophil-to-lymphocyte ratio versus platelet-to-lymphocyte ratio in predicting clinical outcomes in acute methanol poisoning10
Circ_0006220 promotes non-small cell lung cancer progression via sponging miR-203-3p and regulating RGS17 expression10
Trimethylamine-N oxide enhances post-stroke depression progression via ROS-p38/MAPK signaling10
Outbreaks of mushroom poisoning associated with acute kidney injury10
The effects of ellagic acid and other pomegranate (Punica granatum L.) derivatives on human gastric cancer AGS cells10
Hsa_circ_0000285 knockdown inhibits the progression of hepatocellular carcinoma by sponging miR-582-3p to regulate CCNB2 expression10
Corrigendum to “5-Fluorouracil-induced toxicity in both male and female reproductive systems: A narrative review”10
Carvacrol hinders the progression of hepatic fibrosis via targeting autotaxin and thioredoxin in thioacetamide-induced liver fibrosis in rat9
Effect of nano zinc oxide on proliferation and toxicity of human gingival cells9
Valtrate antagonizes malignant phenotypes of lung cancer cells by reducing SLC7A119
Silencing lncRNA HCG18 regulates GPX4-inhibited ferroptosis by adsorbing miR-450b-5p to avert sorafenib resistance in hepatocellular carcinoma9
Persistent diazinon induced neurotoxicity: The effect on inhibitory avoidance memory performance, amyloid precursor proteins, and TNF-α levels in the prefrontal cortex of rats9
Integrative analysis of renal microRNA and mRNA to identify hub genes and pivotal pathways associated with cyclosporine-induced acute kidney injury in mice9
Oxymatrine attenuates TNBS-induced colinutis in rats through TLR9/Myd88/NF-κB signal pathway9
LINC00641 impeded the malignant biological behaviors of papillary thyroid carcinoma cells via interacting with IGF2BP1 to reduce GLI1 mRNA stability9
Microsomal glutathione S-transferase 1 targets the autophagy signaling pathway to suppress ferroptosis in gastric carcinoma cells9
LINC00265 promotes the viability, proliferation, and migration of bladder cancer cells via the miR-4677-3p/FGF6 axis9
Lipoxin A4 methyl ester protects PC12 cells from ketamine-induced neurotoxicity via the miR-22/BAG5 pathway9
The prognostic value of red cell distribution width for in-hospital mortality in patients with methanol poisoning9
Effect of curcumin on lung epithelial injury and ferroptosis induced by cigarette smoke8
Analysis of kidney proteomes to identify biological pathways associated with vancomycin-induced nephrotoxicity in mice by tandem mass tag-labeled quantitative and parallel reaction monitoring phosphop8
A review of challenges and prospects of 3D cell-based culture models used for studying drug induced liver injury during early phases of drug development8
Overexpression of lncRNA A2M-AS1 inhibits cell growth and aggressiveness via regulating the miR-587/bone morphogenetic protein 3 axis in lung adenocarcinoma8
KLF9 mediates NLRP3 inflammasome and reactive oxygen species to mediate pyroptosis in trophoblasts8
Propofol suppresses proliferation, migration, invasion, and tumor growth of liver cancer cells via suppressing cancer susceptibility candidate 9/phosphatase and tensin homolog/AKT serine/threonine kin8
MAPK-interacting kinases inhibition by eFT508 overcomes chemoresistance in preclinical model of osteosarcoma8
Phillyrin ameliorates diabetic nephropathy through the PI3K/Akt/GSK-3β signalling pathway in streptozotocin-induced diabetic mice8
Targeting p-AKT/mTOR/MAP kinase signaling, NLRP3 inflammasome and apoptosis by fluvastatin with or without taxifolin mitigates gonadal dysfunction induced by bisphenol-A in male rats8
Scutellarin alleviates type 2 diabetes (HFD/low dose STZ)-induced cardiac injury through modulation of oxidative stress, inflammation, apoptosis and fibrosis in mice8
Integrated gut microbiota and serum metabolomics reveal glyphosate-induced hepatic injury in mice8
Prognostic factors of acetaminophen exposure in the United States: An analysis of 39,000 patients8
Prediction of delayed neuropsychiatric sequelae after carbon monoxide poisoning via serial determination of serum neuron-specific enolase levels8
The effects of short-time air pollution, SO2, and ozone on biochemical, histo-pathological, oxidative stress, and carcinogenesis related genes expressions in the liver of the rats8
Biochemical assessment of the neurotoxicity of gold nanoparticles functionalized with colorectal cancer-targeting peptides in a rat model8
Assessment of antidiabetic effect of 4-HIL in type 2 diabetic and healthy Sprague Dawley rats8
Serum and glucocorticoid inducible kinase 1 modulates mitochondrial dysfunction and oxidative stress in doxorubicin-induced cardiomyocytes by regulating Hippo pathway via Neural precursor cell-express7
Arsenic-induced downregulation of BRWD3 suppresses proliferation and induces apoptosis in lung adenocarcinoma cells through the p53 and p65 pathways7
Agmatine mitigates palmitate (PA)-induced mitochondrial and metabolic dysfunction in microvascular endothelial cells7
Anti-EMT properties of ergothioneine attenuate lipopolysaccharide-induced oxidative stress-mediated acute lung injury via modulating TGF-β/smad/snail signaling pathway7
Benzodiazepine exposures among women of reproductive age in the US, 2004–20187
Evaluation of antioxidant properties and cytotoxicity of brown algae (nizamuddinia zanardinii) in uterine (hela) and pancreatic cancer cell lines (paca-2)7
Trans-resveratrol alleviates hepatic and renal injury in γ-irradiated rats7
Knockdown of LINC00511 decreased cisplatin resistance in non-small cell lung cancer by elevating miR-625 level to suppress the expression of leucine rich repeat containing eight volume-regulated anion7
Reassessing clinical presentations of emamectin benzoate poisoning: A comprehensive study7
A reply to a letter to the editor7
RETRACTION NOTICE: Neuroprotection of chromobox seven knockout in the mouse after cerebral ischemia-reperfusion injury via nuclear factor E2-related factor 2/hemeoxygenase-1 signaling pathway7
Niosome-carvedilol protects DNA damage of supraphysiologic concentrations of insulin using comet assay: An in vitro study7
Retraction Notice: “Sulforaphane triggers iron overload-mediated ferroptosis in gastric carcinoma cells by activating the PI3K/IRP2/DMT1 pathway”7
The protective role of curcumin against toxic effect of nonylphenol on bone development7
Neuroprotective effect of miR-204-5p downregulation against isoflurane-induced learning and memory impairment via targeting EphB2 and inhibiting neuroinflammation7
Neurotoxic 18-kDa apolipoprotein E fragment production contributes to anesthetic sevoflurane-induced tau phosphorylation and neuroinflammation in vitro7
Oxidative stress reactions in rats with pulmonary injuries induced by sulfur mustard (1 LD50)7
Methylation patterns of the CDKN2B and CDKN2A genes in an indigenous population exposed to pesticides7
Curcumin treatment attenuates cisplatin-induced gastric mucosal inflammation and apoptosis through the NF- κ B and MAPKs signaling pathway7
Ursolic acid inhibits proliferation, migration and invasion of human papillary thyroid carcinoma cells via CXCL12/CXCR4/CXCR7 axis through cancer-associated fibroblasts7
Mechanism of action of curcumin targeting TRPM2/NLRP3 signaling axis to mediate cell death in the treatment of knee osteoarthritis7
Evaluation of the effectiveness of fresh frozen plasma transfusion as adjuvant treatment in acute organophosphate-poisoned patients: A randomized clinical trial7
Antenatal dexamethasone retarded fetal long bones growth and development by down-regulating of insulin-like growth factor 1 signaling in fetal rats7
Semaglutide ameliorates lipopolysaccharide-induced acute lung injury through inhibiting HDAC5-mediated activation of NF-κB signaling pathway7
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