Cell Proliferation

Article	Citations
	273
TRAPPC2l Participates in Male Germ Cell Development by Regulating Cell Division	214
Mechanisms and therapeutic potential of disulphidptosis in cancer	168
CD33‐targeting extracellular vesicles deliver antisense oligonucleotides against FLT3‐ITD and miR‐125b for specific treatment of acute myeloid leukaemia	132
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The beneficial effects of chick embryo extract preconditioning on hair follicle stem cells: A promising strategy to generate Schwann cells	78
ZNF281 drives hepatocyte senescence in alcoholic liver disease by reducing HK2‐stabilized PINK1/Parkin‐mediated mitophagy	74
Epidermal growth factor induces a trophectoderm lineage transcriptome resembling that of human embryos during reconstruction of blastoids from extended pluripotent stem cells	72
Transplantation of Wnt4‐modified neural stem cells mediate M2 polarization to improve inflammatory micro‐environment of spinal cord injury	68
Proteome analysis develops novel plasma proteins classifier in predicting the mortality of COVID‐19	67
Osteoblasts impair cholesterol synthesis in chondrocytes via Notch1 signalling	67
Dynamic immune cell profiling identified natural killer cell shift as the key event in early allograft dysfunction after liver transplantation	65
Rack1‐mediated ferroptosis affects hindgut development in rats with anorectal malformations: Spatial transcriptome insights	62
LL‐37 Inhibits TMPRSS2‐Mediated S2' Site Cleavage and SARS‐CoV‐2 Infection but Not Omicron Variants	60
A Chemical Reprogramming Approach Efficiently Producing Human Retinal Pigment Epithelium Cells for Retinal Disease Therapies	57
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Dermal papilla cells and melanocytes response to physiological oxygen levels depends on their interactions	54
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CTCF Point Mutation at R567 Disrupts Mouse Heart Development via 3D Genome Rearrangement and Transcription Dysregulation	48
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Klotho Regulates Club Cell Senescence and Differentiation in Chronic Obstructive Pulmonary Disease	46
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Decoding the Molecular Landscape of Prepubertal Oocyte Maturation: GTPBP4 as a Key Driver of In Vitro Developmental Competence	45

Ciliary IFT‐B Transportation Plays an Important Role in Human Endometrial Receptivity Establishment and is Disrupted in Recurrent Implantation Failure Patients	45
RBM39 Promotes Base Excision Repair to Facilitate the Progression of HCC by Stabilising OGG1 mRNA	42
Platelet‐rich plasma‐derived extracellular vesicles: A superior alternative in regenerative medicine?	41
Nivalenol affects Cyclin B1 level and activates SAC for cell cycle progression in mouse oocyte meiosis	41
Small‐molecule‐driven direct reprogramming of Müller cells into bipolar‐like cells	41
ISRIB facilitates the co‐culture of human trophoblast stem cells and embryonic stem cells	40
Circular RNA hsa_circ_0083756 promotes intervertebral disc degeneration by sponging miR‐558 and regulating TREM1 expression	40
Self‐assembled human placental model from trophoblast stem cells in a dynamic organ‐on‐a‐chip system	40
An aggregation of human embryonic and trophoblast stem cells reveals the role of trophectoderm on epiblast differentiation	39
AAV‐mediated gene therapy restores natural fertility and improves physical function in the Lhcgr‐deficient mouse model of Leydig cell failure	38
SOX2 plays a crucial role in cell proliferation and lineage segregation during porcine pre‐implantation embryo development	37
Tetrahedral framework nucleic acids‐based delivery of microRNA‐155 alleviates intervertebral disc degeneration through targeting Bcl‐2/Bax apoptosis pathway	37
Mitochondrial Calcium uniporters are essential for meiotic progression in mouse oocytes by controlling Ca2+ entry	36
Deficiency of Aging‐Related Gene Chitinase‐Like 4 Impairs Olfactory Epithelium Homeostasis	36
Role of the CCL2‐CCR2 signalling axis in cancer: Mechanisms and therapeutic targeting	35
Liver microphysiological platforms for drug metabolism applications	35
Research progress on the hedgehog signalling pathway in regulating bone formation and homeostasis	35
Piezo1‐mediated M2 macrophage mechanotransduction enhances bone formation through secretion and activation of transforming growth factor‐β1	34
Corrigendum	34
G3BP1 coordinates lysophagy activity to protect against compression‐induced cell ferroptosis during intervertebral disc degeneration	33
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Single‐cell RNA sequencing: Inhibited Notch2 signalling underlying the increased lens fibre cells differentiation in high myopia	33
Adult progenitor rejuvenation with embryonic factors	33
Velvet antler water extract protects porcine oocytes from lipopolysaccharide‐induced meiotic defects	33
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Corrigendum	32
Mass cytometry and transcriptomic profiling reveal body‐wide pathology induced by Loxl1 deficiency	32
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Effect of tetrahedral framework nucleic acids on the reconstruction of tendon‐to‐bone injuries after rotator cuff tears	30
Accelerating Bone Healing With METTL3 Overexpressed Adipose‐Derived Stem Cells in Osteoporotic Rats	30
The mitochondrial‐endoplasmic reticulum co‐transfer in dental pulp stromal cell promotes pulp injury repair	29
Potential roles of enteric glial cells in Crohn's disease: A critical review	29
Stroke‐Homing Peptide‐DNase1 Alleviates Intestinal Ischemia Reperfusion Injury by Selectively Degrading Neutrophil Extracellular Traps	29
Integration of human organoids single‐cell transcriptomic profiles and human genetics repurposes critical cell type‐specific drug targets for severe COVID‐19	28
LRH‐1 activation alleviates diabetes‐induced podocyte injury by promoting GLS2‐mediated glutaminolysis	28
Identification of oogonial stem cells in chicken ovary	27
The inhibition of enterocyte proliferation by lithocholic acid exacerbates necrotizing enterocolitis through downregulating the Wnt/β‐catenin signalling pathway	26
Preventing acute liver injury via hepatocyte‐targeting nano‐antioxidants	26
Role of hydrogen sulphide in physiological and pathological angiogenesis	26
MUSTN1 Interaction With SMPX Regulates Muscle Development and Regeneration	26
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Single‐cell transcriptome analysis reveals defective decidua stromal niche attributes to recurrent spontaneous abortion	25
Corrigendum	25
Post‐hospitalization rehabilitation alleviates long‐term immune repertoire alteration in COVID‐19 convalescent patients	24
Multi‐Omics Reveal the Metabolic Changes in Cumulus Cells During Aging	24
Lin28a forms an RNA‐binding complex with Igf2bp3 to regulate m6A‐modified stress response genes in stress granules of muscle stem cells	24
Glutaminase‐1 Mediated Glutaminolysis to Glutathione Synthesis Maintains Redox Homeostasis and Modulates Ferroptosis Sensitivity in Cancer Cells	24
Single‐cell RNA sequencing reveals new subtypes of lens superficial tissue in humans	23
Baffled‐flow culture system enables the mass production of megakaryocytes from human embryonic stem cells by enhancing mitochondrial function	23

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Opposite roles of Kindlin orthologs in cell survival and proliferation	23
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Probiotics ameliorate alveolar bone loss by regulating gut microbiota	22
Wnt10b regulates osteogenesis of adipose‐derived stem cells through Wnt/β‐catenin signalling pathway in osteoporosis	22
A chemically defined system supports two distinct types of stem cell from a single blastocyst and their self‐assembly to generate blastoid	22
WNT16b promotes the proliferation and self‐renewal of human limbal epithelial stem/progenitor cells via activating the calcium/calcineurin A/NFATC2 pathway	22
Exosomes on the development and progression of renal fibrosis	21
RETRACTION: Legionella Pneumophila Infection Reduces the Mitochondrial Membrane Potential Through Lpg2444‐Inhibited Mitocytosis	20
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CircSMAD3 represses VSMC phenotype switching and neointima formation via promoting hnRNPA1 ubiquitination degradation	20
GANT61 Modulates Autophagy and Lipid Metabolism in Ovarian Cancer	20
Rapid and Effective Neuronal Conversion of Human Glioblastoma In Vitro and In Vivo Using Potent Small Molecules	20
Developmental switch from morphological replication to compensatory growth for salamander lung regeneration	20
Flavonoid chrysin activates both TrkB and FGFR1 receptors while upregulates their endogenous ligands such as brain derived neurotrophic factor to promote human neurogenesis	20
Tetrahedral Framework Nucleic Acid‐Based Delivery of DJ‐1‐saRNA Prevent Retinal Ischaemia–Reperfusion Injury via Inhibiting Ferroptosis	20
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Corrigendum	20
Conditional Overexpression of Net1 Enhances the Trans‐Differentiation of Lgr5+ Progenitors into Hair Cells in the Neonatal Mouse Cochlea	20
Correction to “Memory Inflation: Beyond the Acute Phase of Viral Infection”	20
CircNFIX regulates chondrogenesis and cartilage homeostasis by targeting the miR758‐3p/KDM6A axis	19
The proliferative and multipotent epidermal progenitor cells for human skin reconstruction in vitro and in vivo	19
Ubiquitin‐specific peptidases: Players in bone metabolism	19
RNF20 affects porcine adipocyte differentiation via regulation of mitotic clonal expansion	19
In vivo development and single‐cell transcriptome profiling of human brain organoids	19
The combination of dextran sulphate and polyvinyl alcohol prevents excess aggregation and promotes proliferation of pluripotent stem cells in suspension culture	19
Combination of chemically modified SDF‐1α mRNA and small skin improves wound healing in diabetic rats with full‐thickness skin defects	18
The Application of Polymeric Nanoparticles as Drug Delivery Carriers to Cells in Neurodegenerative Diseases	18
Increased SPON1 promotes pancreatic ductal adenocarcinoma progression by enhancing IL‐6 trans‐signalling	18
Oxidative stress in intervertebral disc degeneration: Molecular mechanisms, pathogenesis and treatment	18
m6A promotes planarian regeneration	18
Issue Information	18
Single‐cell RNA sequencing to explore cancer‐associated fibroblasts heterogeneity: “Single” vision for “heterogeneous” environment	18
Extraembryonic mesoderm cells derived from human embryonic stem cells rely on Wnt pathway activation	18
Supplementation of mitochondria from endometrial mesenchymal stem cells improves oocyte quality in aged mice	18
BCL2‐associated athanogene 6 exon24 contributes to testosterone synthesis and male fertility in mammals	18
Osteocyte ferroptosis induced by ATF3/TFR1 contributes to cortical bone loss during ageing	18
Directed differentiation of human embryonic stem cells into parathyroid cells and establishment of parathyroid organoids	17
Scalable preparation of osteogenic micro‐tissues derived fromhESC‐derived immunity‐and‐matrix‐regulatory cells within porous microcarriers in suspension culture	17
Melatonin alleviates vascular endothelial cell damage by regulating an autophagy‐apoptosis axis in Kawasaki disease	17
Ex vivo factor VIII‐modified proliferating human hepatocytes therapy for haemophilia A	17
Adult spinal cord tissue transplantation combined with local tacrolimus sustained‐release collagen hydrogel promotes complete spinal cord injury repair	17
Manufacturing with pluripotent stem cells (PSConf 2021): Key issues for future research and development	17
Genome‐Wide Screening in Haploid Stem Cells Reveals Synthetic Lethality Targeting MLH1 and TP53 Deficient Tumours	17
Telomere shortening impairs alveolar regeneration	17
Optimizing in vitro T cell differentiation by using induced pluripotent stem cells with GFP‐RUNX1 and mCherry‐TCF7 labelling	17
Progression of irradiated mesenchymal stromal cells from early to late senescence: Changes in SASP composition and anti‐tumour properties	16
Enhancing targeted transgene knock‐in by donor recruitment	16
SETDB1 regulates microtubule dynamics	16
Functional cooperation between IKCa and TRPC1 channels regulates serum‐induced vascular smooth muscle cell proliferation via mediating Ca2+ influx and	16
Comprehensive analysis of human chorionic membrane extracts regulating mesenchymal stem cells during osteogenesis	16
Issue Information	16
Fine‐tuning of dual‐SMAD inhibition to differentiate human pluripotent stem cells into neural crest stem cells	16
Establishment of human corneal epithelial organoids for ex vivo modelling dry eye disease	16
Circ‐CTNNB1 drives aerobic glycolysis and osteosarcoma progression via m6A modification through interacting with RBM15	16
Selective utilization of non‐homologous end‐joining and homologous recombination for DNA repair during meiotic maturation in mouse oocytes	15
Ellagic Acid‐Loaded sEVs Encapsulated in GelMA Hydrogel Accelerate Diabetic Wound Healing by Activating EGFR on Skin Repair Cells	15
The Dual Roles of Lamin A/C in Macrophage Mechanotransduction	15
Super‐Enhancer Target Gene CBP/p300‐Interacting Transactivator With Glu/Asp‐Rich C‐Terminal Domain, 2 Cooperates With Transcription Factor Forkhead Box J3 to Inhibit Pulmonary Va	15
Dnmt1 is required for the development of auditory organs via cell cycle arrest and Fgf signalling	15
Histone H2B ubiquitination mediated chromatin relaxation is essential for the induction of somatic cell reprogramming	15
LincRNA‐EPS inhibits caspase‐11 and NLRP3 inflammasomes in gingival fibroblasts to alleviate periodontal inflammation	15
AFF4 regulates osteogenic potential of human periodontal ligament stem cells via mTOR‐ULK1‐autophagy axis	15
HDAC3 in action: Expanding roles in inflammation and inflammatory diseases	15
Manufacturing clinical‐grade human induced pluripotent stem cell‐derived beta cells for diabetes treatment	15
Correction to “Functional extracellular matrix hydrogel modified with MSC‐derived small extracellular vesicles for chronic wound healing”	15
NRF1 promotes primordial germ cell development, proliferation and survival	15
Decellularised spinal cord matrix manipulates glial niche into repairing phase via serglycin‐mediated signalling pathway	15
Splicing control by PHF5A is crucial for melanoma cell survival	15
GFI1 regulates chromatin state essential in human endothelial‐to‐haematopoietic transition	14
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3D printed PCLA scaffold with nano‐hydroxyapatite coating doped green tea EGCG promotes bone growth and inhibits multidrug‐resistant bacteria colonization	14
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Thymopentin alleviates premature ovarian failure in mice by activating YY2/Lin28A and inhibiting the expression of let‐7 family microRNAs	14
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Urolithin B suppressed osteoclast activation and reduced bone loss of osteoporosis via inhibiting ERK/NF‐κB pathway	13
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Exercise Delays Brain Ageing Through Muscle‐Brain Crosstalk	13
An allied reprogramming, selection, expansion and differentiation platform for creating hiPSC on microcarriers	13
Effects of astragaloside IV on glucocorticoid‐induced avascular necrosis of the femoral head via regulating Akt‐related pathways	13
Premeiotic deletion of Eif2s2 causes oocyte arrest at the early diplotene stage and apoptosis in mice	13
A DNA nanostructure‐Hif‐1α inducer complex as novel nanotherapy against cisplatin‐induced acute kidney injury	13
Cisplatin‐induced oxPAPC release enhances MDSCs infiltration into LL2 tumour tissues through MCP‐1/CCL2 and LTB4/LTB4R pathways	13
GDF11 inhibits adipogenesis and improves mature adipocytes metabolic function via WNT/β‐catenin and ALK5/SMAD2/3 pathways	13
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Heterogeneous stiffness of the bone marrow microenvironment regulates the fate decision of haematopoietic stem and progenitor cells	13
Abnormal microglial polarization induced by Arid1a deletion leads to neuronal differentiation deficits	13
Eukaryotic translation initiation factor eIF4G2 opens novel paths for protein synthesis in development, apoptosis and cell differentiation	13
Immune repertoire analysis of normal Chinese donors at different ages	13
A regulatory loop of JAK/STAT signalling and its downstream targets represses cell fate conversion and maintains male germline stem cell niche homeostasis	12
Nutrient metabolism in regulating intestinal stem cell homeostasis	12
Single‐cell RNA sequencing in osteoarthritis	12
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Sirt3 Rescues Porphyromonas gingivalis‐Impaired Cementogenesis via SOD2 Deacetylation	12
Cholestyramine alleviates bone and muscle loss in irritable bowel syndrome via regulating bile acid metabolism	12
Transcriptome profiles and chromatin states in mouse androgenetic haploid embryonic stem cells	12
MET overexpression in ovarian cancer via CD24‐induced downregulation of miR‐181a: A signalling for cellular quiescence‐like state and chemoresistance in ovarian C	12
AMPK regulates homeostasis of invasion and viability in trophoblasts by redirecting glucose metabolism: Implications for pre‐eclampsia	12
Correction to ‘BMAL1 deficiency promotes skeletal mandibular hypoplasia via OPG downregulation’	12
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Establishment and characterization of adult human gastric epithelial progenitor‐like cell lines	12
Non‐SMC condensin I complex subunit H participates in anti‐programmed cell death‐1 resistance of clear cell renal cell carcinomas	12
GPD1L‐Mediated Glycerophospholipid Metabolism Dysfunction in Women With Diminished Ovarian Reserve: Insights From Pseudotargeted Metabolomic Analysis of Follicular Fluid	12
Organoid Models to Study Human Infectious Diseases	12
Knowledge graphs of ethical concerns of cerebral organoids	12
RNA‐binding protein ELAVL2 plays post‐transcriptional roles in the regulation of spermatogonia proliferation and apoptosis	12
Sprouty1 exerts a preventive effect on the initiation of psoriasis by inhibiting innate immune antimicrobial peptide cathelicidin and immunocytes	12
An RNA methylation code to regulate protein translation and cell fate	12
The role of Trithorax family regulating osteogenic and Chondrogenic differentiation in mesenchymal stem cells	11
Histatin 1 enhanced the speed and quality of wound healing through regulating the behaviour of fibroblast	11
Generation of stable integration‐free pig induced pluripotent stem cells under chemically defined culture condition	11
Requirements for human cardiomyocytes	11
Cystathionine β‐synthase is required for oocyte quality by ensuring proper meiotic spindle assembly	11
The intact parasympathetic nerve promotes submandibular gland regeneration through ductal cell proliferation	11
T‐cell infiltration, contribution and regulation in the central nervous system post‐traumatic injury	11
YTHDC1 positively regulates PTEN expression and plays a critical role in cisplatin resistance of bladder cancer	11
Colony‐stimulating factor 1 positive (CSF1+) secretory epithelial cells induce excessive trophoblast invasion in tubal pregnancy rupture	11
PFKFB4 facilitates palbociclib resistance in oestrogen receptor‐positive breast cancer by enhancing stemness	11
Requirements for human‐induced pluripotent stem cells	11
Partial depletion and repopulation of microglia have different effects in the acute MPTP mouse model of Parkinson’s disease	11
Scalable manufacturing of clinical‐grade differentiated cardiomyocytes derived from human‐induced pluripotent stem cells for regenerative therapy	10
Adverse PFAS effects on mouse oocyte in vitro maturation are associated with carbon‐chain length and inclusion of a sulfonate group	10
HN1 Functions in Protein Synthesis Regulation via mTOR‐RPS6 Axis and Maintains Nucleolar Integrity	10
Single‐Cell Multiomics Reveals TCR Clonotype‐Specific Phenotype and Stemness Heterogeneity of T‐ALL Cells	10
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Interfering with CSE1L/CAS inhibits tumour growth via C3 in triple‐negative breast cancer	10
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Exploring the Single‐Cell Dynamics of FOXM1 Under Cell Cycle Perturbations	10
Investigating Aging‐Related Endometrial Dysfunction Using Endometrial Organoids	10
IKK/NF‐κB and ROS signal axes are involved in Tenacissoside H mediated inhibitory effects on LPS‐induced inflammatory osteolysis	10
Bone marrow macrophage‐derived exosomal miR‐143‐5p contributes to insulin resistance in hepatocytes by repressing MKP5	10
The role of Espin in the stereocilia regeneration and protection in Atoh1‐overexpressed cochlear epithelium	10
Utilising Human Myometrial and Uterine Fibroid Stem Cell‐Derived Three Dimentional Organoids as a Robust Model System for Understanding the Pathophysiology of Uterine Fibroids	10
RETRACTION: MATN1‐AS1 promotes glioma progression by functioning as ceRNA of miR‐200b/c/429 to regulate CHD1 expression	10
Intermittent hyperglycaemia induces macrophage dysfunction by extracellular regulated protein kinase‐dependent PKM2 translocation in periodontitis	9
SESN1 is a FOXO3 effector that counteracts human skeletal muscle ageing	9
Single‐cell RNA sequencing gene signatures for classifying and scoring exhausted CD8+ T cells in B‐cell acute lymphoblastic leukaemia	9
Intra‐amniotic mesenchymal stem cell therapy improves the amniotic fluid microenvironment in rat spina bifida aperta fetuses	9
Optineurin Cooperates With NRF2 to Regulate Tooth Root Morphogenesis by Controlling Mitochondrial Dynamics and Apoptosis	9
Lactate‐induced protein lactylation: A bridge between epigenetics and metabolic reprogramming in cancer	9
Comparison of seven CD19 CAR designs in engineering NK cells for enhancing anti‐tumour activity	9
Identifying the key genes of Epstein–Barr virus‐regulated tumour immune microenvironment of gastric carcinomas	9
Mitochondrial dysfunction is associated with hypertrophic cardiomyopathy in Pompe disease‐specific induced pluripotent stem cell‐derived cardiomyocytes	9
Metabolomics analyses reveal the crucial role of ERK in regulating metabolic pathways associated with the proliferation of human cutaneous T‐cell lymphoma cells treated with Glabridin	9
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Reduced M2 macrophages and adventitia collagen dampen the structural integrity of blood blister–like aneurysms and induce preoperative rerupture	9
Perfect duet: Dual recombinases improve genetic resolution	9
ZFP541 and KCTD19 regulate chromatin organization and transcription programs for male meiotic progression	9
Single‐Cell Transcriptomics Uncovers Core Signature for Regulating Mitochondrial Homeostasis During Testicular Ageing	9
Protective roles of cytoplasmic p21Cip1/Waf1 in senolysis and ferroptosis of lung cancer cells	9
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PAPPA2 mutation as a novel indicator stratifying beneficiaries of immune checkpoint inhibitors in skin cutaneous melanoma and non‐small cell lung cancer	9
In vitro construction of liver organoids with biomimetic lobule structure by a multicellular 3D bioprinting strategy	9
Reduced ELANE and SLPI expression compromises dental pulp cell activity	9
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NAT10‐mediated ac4C modification promotes ectoderm differentiation of human embryonic stem cells via acetylating NR2F1 mRNA	9
Suppression of SLC39A6‐CREB1 axis in liver cancer causes PCK1‐mediated mitochondrial dysfunction	9
eIF3a‐PPP2R5A‐mediated ATM/ATR dephosphorylation is essential for irinotecan‐induced DNA damage response	9
Mitonuclear Communication in Stem Cell Function	9
RETRACTION: Six2 Promotes Non–Small Cell Lung Cancer Cell Stemness Via Transcriptionally and Epigenetically Regulating E‐Cadherin	9
Deciphering the Immunomodulatory Function of GSN+ Inflammatory Cancer‐Associated Fibroblasts in Renal Cell Carcinoma Immunotherapy: Insights From Pan‐Cancer Single‐Cell Landscape	9
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Constitutively activated AMPKα1 protects against skeletal aging in mice by promoting bone‐derived IGF‐1 secretion	9
IMPDH2's Central Role in Cellular Growth and Diseases: A Potential Therapeutic Target	9