OOIR: Observatory of International Research

Papers

(The H4-Index of Bioorganic & Medicinal Chemistry Letters is 28. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)

Article	Citations
Discovery of N-(6-(5-fluoro-2-(piperidin-1-yl)phenyl)pyridazin-3-yl)-1-(tetrahydro-2H-pyran-4-yl)methanesulfonamide as a brain-permeable and metabolically stable kynurenine monooxygenase inhibitor	152
Design, synthesis and biological evaluation of alginate oligosaccharide derivatives	85
Amyloidogenic immunoglobulin light chain kinetic stabilizers comprising a simple urea linker module reveal a novel binding sub-site	73
Design, synthesis and biological evaluation of tanshinone IIA derivatives as NLRP3 inflammasome inhibitors	67
Enteroviral replication inhibition by N-Alkyl triazolopyrimidinone derivatives through a non-capsid binding mode	66
Revisiting the dipeptidyl carboxypeptidase inhibitor captopril as a source of pan anti-trypanosomatid agents	54
Novel carbohydrate-based sulfonamide derivatives as selective carbonic anhydrase II inhibitors: Synthesis, biological and molecular docking analysis	53
Editorial Board	51
Synthesis and SAR of novel GPR39 agonists and positive allosteric modulators	44
Design of 99mTc-labeled zinc-chelating imaging probe for SPECT imaging of the pancreas	41
Graphical Abstract TOC	41
Discovery of structural diverse reversible BTK inhibitors utilized to develop a novel in vivo CD69 and CD86 PK/PD mouse model	41
Discovery of 3-amino-4-{(3S)-3-[(2-ethoxyethoxy)methyl]piperidin-1-yl}thieno[2,3-b]pyridine-2-carboxamide (DS96432529): A potent and orally active bone anabolic agent	37
Studies on in vitro modulatory effects to base excision repair enzymes induced by small molecule binding to Deaminated CAG repeat hairpin	37
Editorial Board	37
Editorial Board	36
Non-alkylator anti-glioblastoma agents induced cell cycle G2/M arrest and apoptosis: Design, in silico physicochemical and SAR studies of 2-aminoquinoline-3-carboxamides	34
Discovery of DS-1093a: An oral hypoxia-inducible factor prolyl hydroxylase inhibitor for the treatment of renal anemia	33
New class of fused [3,2-b][1,2,4]triazolothiazoles for targeting glioma in vitro	33
Discovery of novel iminosydnone compounds with insecticidal activities based on the binding mode of triflumezopyrim	32
A fluorescent molecular rotor for the selective detection of the hybrid-conformation 22AG G-Quadruplex	31
Design, synthesis, biological evaluation and molecular modeling of N-isobutyl-N-((2-(p-tolyloxymethyl)thiazol-4yl)methyl)benzo[d][1,3] dioxole-5-carboxamides as selective butyrylcholinesterase inhibit	31
Phytochemical investigation of Asarum sieboldii var. seoulense and the phenotypic profiles of its constituents against a Parkinson’s Disease olfactory cell line	30
Improved synthesis and anticancer activity of a potent neuronal nitric oxide synthase inhibitor	30
Design and evaluation of anaplastic lymphoma kinase degraders using a covalent fumarate handle	29

Neuropilin 1-targeted near-infrared fluorescence probes for tumor diagnosis	29
The ester derivatives obtained by C-ring modification of podophyllotoxin induce apoptosis and inhibited proliferation in PC-3M cells via down-regulation of PI3K/Akt signaling pathway	28
Epigallocatechin and epigallocatechin-3-gallate are not inhibitors of tyrosinase	28