OOIR: Observatory of International Research

Papers

(The H4-Index of Protein Science is 36. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Electronegative clusters modulate folding status and RNA binding of unstructured RNA‐binding proteins	1363
Helicobacter pylori FlgN binds its substrate FlgK and the flagellum ATPase FliI in a similar manner observed for the FliT chaperone	1178
Dimerization of the CNNM extracellular domain	507
Cover Image	348
Issue information	323
Structural insights into the unique recognition module between α‐synuclein peptide and nanobody	243
Escherichia coli strains with precise domain deletions in the ribonuclease RNase E can achieve greatly enhanced levels of membrane protein production	211
Structural and functional validation of a highly specific Smurf2 inhibitor	202
The Phenix‐AlphaFold webservice: Enabling AlphaFold predictions for use in Phenix	189
Issue information	167
Protein salvage and repurposing in evolution: Phospholipase D toxins are stabilized by a remodeled scrap of a membrane association domain	130
ParSe 2.0: A web tool to identify drivers of protein phase separation at the proteome level	121
Binding specificity of type three secretion system effector NleH2 to multi‐cargo chaperone CesT and their phosphorylation	113
Characterization of the SARS‐CoV‐2 E Protein: Sequence, Structure, Viroporin, and Inhibitors	112
Evolutionary analysis of Quinone Reductases 1 and 2 suggests that NQO2 evolved to function as a pseudoenzyme	95
Protection by desiccation‐tolerance proteins probed at the residue level	90
CC⁺: A searchable database of validated coiled coils in PDB structures and AlphaFold2 models	88
Cover Image	86
Synthetic antibodies block receptor binding and current‐inhibiting effects of α‐cobratoxin from Naja kaouthia	82
Arginine cluster introduction on framework region in anti‐lysozyme antibody improved association rate constant by changing conformational diversity of CDR loops	76
Cover Image	71
Structure determination of an unstable macromolecular complex enabled by nanobody‐peptide bridging	68
Cover Image	60
In This Issue	58
	57

Structural studies of intrinsically disordered MLL‐fusion protein AF9 in complex with peptidomimetic inhibitors	56
How hydrophobicity, side chains, and salt affect the dimensions of disordered proteins	56
Reconstitution and characterization of BRAF in complex with 14‐3‐3 and KRAS4B on nanodiscs	54
An ensemble machine learning model generates a focused screening library for the identification of CDK8 inhibitors	52
Characterization of a novel format scFv×VHH single‐chain biparatopic antibody against metal binding protein MtsA	51
Engineering G protein‐coupled receptors for stabilization	50
Native ion mobility‐mass spectrometry reveals the binding mechanisms of anti‐amyloid therapeutic antibodies	50
Effects of N‐ and C‐terminal regions on oligomeric formation of blue light sensor protein SyPixD	45
In vitro characterization of the intramelanosomal domain of human recombinant TYRP1 and its oculocutaneous albinism type 3‐related mutant variants	44
Molecular insights into alginate β‐lactoglobulin A multivalencies—The foundation for their amorphous aggregates and coacervation	42
Substrate binding in the allosteric site mimics homotropic cooperativity in the SIS‐fold glucosamine‐6‐phosphate deaminases	40
	36