OOIR: Observatory of International Research

Papers

(The H4-Index of Protein Science is 37. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)

Article	Citations
	2214
	1472
Design of an effective small expression tag to enhance GPCR production in E. coli‐based cell‐free and whole cell expression systems	463
Kinetic evidence for multiple aggregation pathways in antibody light chain variable domains	276
Molecular mechanism of Fe³⁺ binding inhibition to Vibrio metschnikovii ferric ion‐binding protein, FbpA, by rosmarinic acid and its hydrolysate, danshensu	273
Helicobacter pylori FlgN binds its substrate FlgK and the flagellum ATPase FliI in a similar manner observed for the FliT chaperone	253
Solution structure of the Z0 domain from transcription repressor BCL11A sheds light on the sequence properties of protein‐binding zinc fingers	243
Fine‐tuned interactions between globular and disordered regions of single‐stranded DNA binding (SSB) protein are required for dynamic condensation under physiological conditions	156
Epitope‐directed anti‐SARS‐CoV‐2 scFv engineered against the key spike protein region could block membrane fusion	153
Effects of N‐ and C‐terminal regions on oligomeric formation of blue light sensor protein SyPixD	138
Substrate binding in the allosteric site mimics homotropic cooperativity in the SIS‐fold glucosamine‐6‐phosphate deaminases	136
Issue information	113
Evolution of affinity between p53 transactivation domain and MDM2 across the animal kingdom demonstrates high plasticity of motif‐mediated interactions	108
Biophysical insights into the dimer formation of human Sirtuin 2	106
BEAN and HABAS: Polyphyletic insertions in the DNA‐directed RNA polymerase	106
CsgA gatekeeper residues control nucleation but not stability of functional amyloid	85
Biophysical characterization of RelA–p52 NF‐κB dimer—A link between the canonical and the non‐canonical NF‐κB pathway	83
Gating residues govern ligand unbinding kinetics from the buried cavity in HIF‐2α PAS‐B	77
Structure–function mapping and mechanistic insights on the SARS CoV2 Nsp1	74
A novel method for expressing and purifying large quantities of functional and stable human voltage‐gated proton channel (hH_v1)	71
Impact of local unfolding fluctuations on the evolution of regional sequence preferences in proteins	69
Torsional twist of the SARS‐CoV and SARS‐CoV‐2 SUD‐N and SUD‐M domains	66
Cover Image	62
Extrinsic and intrinsic factors affect copper‐induced protein precipitation across eukaryotic and prokaryotic proteomes	61
Active site architecture of coproporphyrin ferrochelatase with its physiological substrate coproporphyrin III: Propionate interactions and porphyrin core deformation	59

An ankyrin repeat chaperone targets toxic oligomers during amyloidogenesis	54
Two residues determine nicotinic acetylcholine receptor requirement for RIC‐3	47
The Phenix‐AlphaFold webservice: Enabling AlphaFold predictions for use in Phenix	46
Similar protein segments shared between domains of different evolutionary lineages	44
Rapid directed molecular evolution of fluorescent proteins in mammalian cells	44
Contributions of the N‐terminal intrinsically disordered region of the severe acute respiratory syndrome coronavirus 2 nucleocapsid protein to RNA‐induced phase separation	42
Soluble SARS‐CoV‐2 RBD and human ACE2 peptidase domain produced in DrosophilaS2 cells show functions evoking virus–cell interface	42
Xplor‐NIH: Better parameters and protocols for NMR protein structure determination	42
Large library docking for novel SARS‐CoV‐2 main protease non‐covalent and covalent inhibitors	42
A multi‐pore model of the blood–brain barrier tight junction strands recapitulates the permeability features of wild‐type and mutant claudin‐5	40
Structural hierarchy of mechanical extensibility in human von Willebrand factor multimers	40
Structural polymorphism and cytotoxicity of brain‐derived β‐amyloid extracts	37