Statistical Methods in Medical Research

Article	Citations
Equivalence tests for ratio of means in bioequivalence studies under crossover design	107
Design and analysis of partially randomized preference trials with propensity score stratification	65
Confidence estimation based on data from independent studies	59
Weighted reverse counting process (WRCP): A novel approach to quantify the overall treatment effect with multiple time-to-event outcomes by adaptive weighting	55
A generalized epidemiological model with dynamic and asymptomatic population	45
Covariate adjustment in Bayesian adaptive randomized controlled trials	34
The “Why” behind including “Y” in your imputation model	33
Simulation extrapolation method for measurement error: A review	26
Regression analysis of longitudinal data with random change point	25
Bivariate copula regression models for semi-competing risks	24
Omnibus test for restricted mean survival time based on influence function	22
Robust integration of secondary outcomes information into primary outcome analysis in the presence of missing data	21
Simultaneous inference procedures for the comparison of multiple characteristics of two survival functions	20
Commentary on the use of the reproduction number R during the COVID-19 pandemic	19
Interval estimation in three-class receiver operating characteristic analysis: A fairly general approach based on the empirical likelihood	18
A review of multistate modelling approaches in monitoring disease progression: Bayesian estimation using the Kolmogorov-Chapman forward equations	18
Solutions to problems of nonexistence of parameter estimates and sparse data bias in Poisson regression	18
Comparison between inverse-probability weighting and multiple imputation in Cox model with missing failure subtype	17
Optimal study designs for cluster randomised trials: An overview of methods and results	17
A general consonance principle for closure tests based on p-values	17
Sample size determination for stepped wedge cluster randomized trials in pragmatic settings	15
Multivariate generalized linear mixed models for continuous bounded outcomes: Analyzing the body fat percentage data	15
Generalized fiducial inference for the restricted mean survival time	15
ROSIE: RObust Sparse ensemble for outlIEr detection and gene selection in cancer omics data	15
Instrumental variable analysis with categorical treatment	14

Editorial	14
A unified approach to power and sample size determination for log-rank tests under proportional and nonproportional hazards	13
Semiparametric copula method for semi-competing risks data subject to interval censoring and left truncation: Application to disability in elderly	12
Sensitivity analysis for unmeasured confounding in estimating the difference in restricted mean survival time	12
Regression analysis of a future state entry time distribution conditional on a past state occupation in a progressive multistate model	11
Improved semi-parametric inference for a mixture model of responses from a control versus treatment group trial	11
Model-based optimal randomization procedure for treatment–covariate interaction tests	11
Simulation models for aggregated data meta-analysis: Evaluation of pooling effect sizes and publication biases	11
Accounting for regression to the mean under the bivariate t-distribution	11
A Bayesian beta-binomial piecewise growth mixture model for longitudinal overdispersed binomial data	11
Semiparametric generalized estimating equations for repeated measurements in cross-over designs	11
Bayesian analysis of joint quantile regression for multi-response longitudinal data with application to primary biliary cirrhosis sequential cohort study	10
A latent class linear mixed model for monotonic continuous processes measured with error	10
Approximate Bayesian computation design for phase I clinical trials	10
Optimal sampling allocation for outcome-dependent designs in cluster-correlated data settings	9
Joint meta-analysis of two diagnostic tests accounting for within and between studies dependence	9
Dynamic survival analysis: Modelling the hazard function via ordinary differential equations	9
Design and analysis of factorial clinical trials: The impact of one treatment's effectiveness on the statistical power and required sample size of the other	8
A new cure model accounting for longitudinal data and flexible patterns of hazard ratios over time	8
Copula modeling for the estimation of measures of marker classification and predictiveness performance with survival outcomes	8
Joint regression analysis of clustered current status data with latent variables	8
Bayesian multiple Gaussian graphical models for multilevel variables from unknown classes	8
Comparison of statistical methods for the analysis of patient-reported outcomes in randomised controlled trials: A simulation study	8
Non-parametric treatment time-lag effect estimation	8
Time-varying coefficient additive hazards model with latent variables	8
Refined moderation analysis with binary outcomes in precision medicine research	8
Estimating drug concentration–response relationships by applying causal inference methods for continuous point exposures and time-to-event outcomes	8
A novel model-checking approach for dose-response relationships	8
Exact interval estimation for the linear combination of binomial proportions	8
Statistical methods for analysis of combined biomarker data from multiple nested case–control studies	8
Analysis of hospital readmissions with competing risks	7
Group lasso priors for Bayesian accelerated failure time models with left-truncated and interval-censored data	7
A comparison of two frameworks for multi-state modelling, applied to outcomes after hospital admissions with COVID-19	7
Heterogeneous treatment effect estimation for observational data using model-based forests	7
Clustering minimal inhibitory concentration data through Bayesian mixture models: An application to detect Mycobacterium tuberculosis resistance mutations	7
Standardization of continuous and categorical covariates in sparse penalized regressions	7
Using dichotomized survival data to construct a prior distribution for a Bayesian seamless Phase II/III clinical trial	7
Estimating target population treatment effects in meta-analysis with individual participant-level data	7
Unbiased and robust analysis of co-localization in super-resolution images	7
Variance estimation for the average treatment effects on the treated and on the controls	7
Use of clinical tolerance limits for assessing agreement	7
Logistic regression with correlated measurement error and misclassification in covariates	7
Partly linear single-index cure models with a nonparametric incidence link function	7
A model-based approach for historical borrowing, with an application to neovascular age-related macular degeneration	7
Relationship between collider bias and interactions on the log-additive scale	7
Sample sizes required to estimate the protective efficacy of a vaccine when there is an unequal allocation of individuals across the vaccine and placebo groups	7
A novel rare variants association test for binary traits in family-based designs via copulas	7
Reference ranges: Why tolerance intervals should not be used. Comment on Liu, Bretz and Cortina-Borja, Reference range: Which statistical intervals to use? SMMR, 2021,Vol. 30(2) 523–534	6
Simultaneous variable selection and estimation for a partially linear Cox model	6
Demystifying estimands in cluster-randomised trials	6

Point estimation following a two-stage group sequential trial	6
Adaptive enrichment trial designs using joint modelling of longitudinal and time-to-event data	6
Combining cox regressions across a heterogeneous distributed research network facing small and zero counts	6
Goodness-of-fit tests for modified Poisson regression possibly producing fitted values exceeding one in binary outcome analysis	6
A matching-based machine learning approach to estimating optimal dynamic treatment regimes with time-to-event outcomes	6
Frequentist rules for regulatory approval of subgroups in phase III trials: A fresh look at an old problem	6
Estimating latent, dynamic processes of breast cancer tumour growth and distant metastatic spread from mammography screening data	6
The staircase cluster randomised trial design: A pragmatic alternative to the stepped wedge	6
Nonparametric Bayesian Q-learning for optimization of dynamic treatment regimes in the presence of partial compliance	6
Estimating the sample mean and standard deviation from order statistics and sample size in meta-analysis	6
On estimation of overall treatment effects in multiregional clinical trials under a discrete random effects model	6
Matching ratio and sample size for optimal sequential testing with binomial data	6
Impact of unequal censoring and insufficient follow-up on comparing survival outcomes: Applications to clinical studies	6
Variance partitioning in spatio-temporal disease mapping models	6
A connection between covariate adjustment and stratified randomization in randomized clinical trials	6
Leveraging historical data to optimize the number of covariates and their explained variance in the analysis of randomized clinical trials.	6
Comparison of parametric and semi-parametric models with randomly right-censored data by weighted estimators: Two applications in colon cancer and hepatocellular carcinoma datasets	5
Accounting for informative observation process in transition models of binary longitudinal outcome: Application to medical record data	5
Weighted functional linear Cox regression model	5
A general averaging method for count data with overdispersion and/or excess zeros in biomedicine	5
Adaptive group sequential survival comparisons based on log-rank and pointwise test statistics	5
Weighted mean difference statistics for paired data in the presence of missing values	5
Analysis of survival data with cure fraction and variable selection: A pseudo-observations approach	5
Bayesian blockwise inference for joint models of longitudinal and multistate data with application to longitudinal multimorbidity analysis	5
A sequential test to compare the real-time fatality rates of a disease among multiple groups with an application to COVID-19 data	5
Bayesian analysis of longitudinal binary responses based on the multivariate probit model: A comparison of five methods	5
Fallopian tube anatomy predicts pregnancy and pregnancy outcomes after tubal reversal surgery	5
Reducing the false discovery rate of preclinical animal research with Bayesian statistical decision criteria	5
Bayesian variable selection in hierarchical difference-in-differences models	5
Model-free screening for variables with treatment interaction	5
Divided-and-combined omnibus test for genetic association analysis with high-dimensional data	5
Marginal semiparametric accelerated failure time cure model for clustered survival data	5
A computationally efficient approach to false discovery rate control and power maximisation via randomisation and mirror statistic	5
Hierarchical continuous-time inhomogeneous hidden Markov model for cancer screening with extensive followup data	5
A functional proportional hazard cure rate model for interval-censored data	5
Average treatment effect on the treated, under lack of positivity	5
Impact of minimal sufficient balance, minimization, and stratified permuted blocks on bias and power in the estimation of treatment effect in sequential clinical trials with a binary endpoint	5
A Bayesian quasi-likelihood design for identifying the minimum effective dose and maximum utility dose in dose-ranging studies	5
A structured iterative division approach for non-sparse regression models and applications in biological data analysis	5
Determination of correlations in multivariate count data with informative observation times	5
Concordance correlation coefficients estimated by modified variance components and generalized estimating equations for longitudinal overdispersed Poisson data	5
Methodology for supervised optimization of the construction of physician shared-patient networks	5
A capture-recapture modeling framework emphasizing expert opinion in disease surveillance	4
Unit information prior for incorporating real-world evidence into randomized controlled trials	4
Improving transportability of randomized controlled trial inference using robust prediction methods	4
An additive-multiplicative model for longitudinal data with informative observation times	4
Distribution-free control charts for mixed-type data based on rank of interpoint distances	4
Flexible semiparametric mode regression for time-to-event data	4
Boosting distributional copula regression for bivariate binary, discrete and mixed responses	4
Evaluations of the sum-score-based and item response theory-based tests of group mean differences under various simulation conditions	4
Using a centered general linear model for detection of interactions among biomarkers	4
Repeated measures discriminant analysis using multivariate generalized estimation equations	4
Developing clinical prediction models when adhering to minimum sample size recommendations: The importance of quantifying bootstrap variability in tuning parameters and predictive performance	4
The joint quantile regression modeling of mixed ordinal and continuous responses with its application to an obesity risk data	4
New clinical trial design borrowing information across patient subgroups based on fusion-penalized regression models	4
Factorial survival analysis for treatment effects under dependent censoring	4
Estimating transformations for evaluating diagnostic tests with covariate adjustment	4
Goodness-of-fit tests for a logistic regression model with missing covariates	4
Generalised pairwise comparisons for trend: An extension to the win ratio and win odds for dose-response and prognostic variable analysis with arbitrary statements of outcome preference	4
Single reader between-cases AUC estimator with nested data	4
An objective Bayesian approach to estimation in multistage experiments	4
A multi-state Markov model using notification data to estimate HIV incidence, number of undiagnosed individuals living with HIV, and delay between infection and diagnosis: Illustration in France, 2008	4
Estimation of the proportion of true null hypotheses under sparse dependence: Adaptive FDR controlling in microarray data	4
Response-adaptive treatment randomization for multiple comparisons of treatments with recurrent event responses	4
Random survival forests with multivariate longitudinal endogenous covariates	4
The benefits of covariate adjustment for adaptive multi-arm designs	4
Between-group comparison of area under the curve in clinical trials with censored follow-up: Application to HIV therapeutic vaccines	4
Unified approach to optimal estimation of mean and standard deviation from sample summaries	4
Combining individual patient data from randomized and non-randomized studies to predict real-world effectiveness of interventions	4
l2-Penalized temporal logit-mixed models for the estimation of regional obesity prevalence over time	4
Multivariate control charts for monitoring a bivariate correlated count process with application to meningococcal disease	4
Quantile outcome adaptive lasso: Covariate selection for inverse probability weighting estimator of quantile treatment effects	4
Data-driven clustering of infectious disease incidence into age groups	3
Generalized Bayesian kernel machine regression	3
Group sequential design using restricted mean survival time as the primary endpoint in clinical trials	3
Nonparametric analysis of doubly truncated and interval-censored data	3
Using joint models for longitudinal and time-to-event data to investigate the causal effect of salvage therapy after prostatectomy	3
The change in estimate method for selecting confounders: A simulation study	3
Nonparametric kernel estimation of the probability of cure in a mixture cure model when the cure status is partially observed	3
Ranking procedures for repeated measures designs with missing data: Estimation, testing and asymptotic theory	3

Ensemble methods for survival function estimation with time-varying covariates	3
A competing risks model with binary time varying covariates for estimation of breast cancer risks in BRCA1 families	3
Modeling comorbidity of chronic diseases using coupled hidden Markov model with bivariate discrete copula	3
Analyzing heterogeneity in biomarker discriminative performance through partial time-dependent receiver operating characteristic curve modeling	3
Risk difference tests for stratified binary data under Dallal’s model	3
Modeling and estimating a threshold effect: An application to improving cardiac surgery practices	3
A Bayesian hierarchical model for disease mapping that accounts for scaling and heavy-tailed latent effects	3
Conversion of non-inferiority margin from hazard ratio to restricted mean survival time difference using data from multiple historical trials	3
A bivariate zero-inflated negative binomial model and its applications to biomedical settings	3
Comparisons of various estimates of the I2 statistic for quantifying between-study heterogeneity in meta-analysis	3
Multiple imputation for cause-specific Cox models: Assessing methods for estimation and prediction	3
Long-term Dagum-power variance function frailty regression model: Application in health studies	3
Using shrinkage methods to estimate treatment effects in overlapping subgroups in randomized clinical trials with a time-to-event endpoint	3
Imputation and missing indicators for handling missing data in the development and deployment of clinical prediction models: A simulation study	3
A new measure to quantify sedentary behavior using accelerometer data: Application to the Hispanic Community Health Study/Study of Latinos	3
Testing for treatment effect in covariate-adaptive randomized trials with generalized linear models and omitted covariates	3
Logistic regression vs. predictive mean matching for imputing binary covariates	3
Flexible joint model for time-to-event and non-Gaussian longitudinal outcomes	3
A Bayesian group lasso classification for ADNI volumetrics data	3
Estimation of covariate effects on net survivals in the relative survival progressive illness-death model	3
Revisiting performance metrics for prediction with rare outcomes	3
Joint modeling of zero-inflated longitudinal measurements and time-to-event outcomes with applications to dynamic prediction	3
MEGH: A parametric class of general hazard models for clustered survival data	3
Correlational analyses of biomarkers that are harmonized through a bridging study due to measurement errors	3
A unified approach to variable selection for Cox’s proportional hazards model with interval-censored failure time data	3
Methods for non-proportional hazards in clinical trials: A systematic review	3
Multiple imputation with missing data indicators	3
Promising zone two-stage design for a single-arm study with binary outcome	3
Detecting the skewness of data from the five-number summary and its application in meta-analysis	3
Challenges of modelling approaches for network meta-analysis of time-to-event outcomes in the presence of non-proportional hazards to aid decision making: Application to a melanoma network	3
LASSO-type instrumental variable selection methods with an application to Mendelian randomization	3
An overview of optimal designs under a given budget in cluster randomized trials with a binary outcome	3
Regularization approaches in clinical biostatistics: A review of methods and their applications	3
Role of calibration in uncertainty-based referral for deep learning	3
Additive hazards model with time-varying coefficients and imaging predictors	3
Mediational g-formula for time-varying treatment and repeated-measured multiple mediators: Application to atorvastatin’s effect on cardiovascular disease via cholesterol lowering and anti-inflammatory	3
Multiplicative versus additive modelling of causal effects using instrumental variables for survival outcomes – a comparison	3
Variable selection for a mark-specific additive hazards model using the adaptive LASSO	3
A state-space approach for longitudinal outcomes: An application to neuropsychological outcomes	3
Approximate Bayesian inference for joint linear and partially linear modeling of longitudinal zero-inflated count and time to event data	2
Fitting joint models of longitudinal observations and time to event by sequential Bayesian updating	2
A dependent circular-linear model for multivariate biomechanical data: Ilizarov ring fixator study	2
Doubly-robust estimator of the difference in restricted mean times lost with competing risks data	2
Revisiting Gaussian Markov random fields and Bayesian disease mapping	2
Causal rule ensemble method for estimating heterogeneous treatment effect with consideration of prognostic effects	2
Compositional functional regression and isotemporal substitution analysis: Methods and application in time-use epidemiology	2
Sample size determination for adaptive crossover trial in detecting gene-drug interactions	2
Unified exact design with early stopping rules for single arm clinical trials with multiple endpoints	2
Saddlepoint approximation p-values of weighted log-rank tests based on censored clustered data under block Efron’s biased-coin design	2
Robust integrative biclustering for multi-view data	2
An iterative matrix uncertainty selector for high-dimensional generalized linear models with measurement errors	2
Generalized quasi-linear mixed-effects model	2
A framework for testing non-inferiority in a three-arm, sequential, multiple assignment randomized trial	2
The performance of marginal structural models for estimating risk differences and relative risks using weighted univariate generalized linear models	2
Quantifying proportion of treatment effect by surrogate endpoint under heterogeneity	2
Familywise error rate control for block response-adaptive randomization	2
Sample size estimation for comparing dynamic treatment regimens in a SMART: A Monte Carlo-based approach and case study with longitudinal overdispersed count outcomes	2
Causal mediation analysis with multiple causally non-ordered and ordered mediators based on summarized genetic data	2
Sensitivity analysis for calibrated inverse probability-of-censoring weighted estimators under non-ignorable dropout	2
Semiparametric estimation of the proportional rates model for recurrent events data with missing event category	2
Analyzing the overall effects of the microbiome abundance data with a Bayesian predictive value approach	2
Simulating time-to-event data subject to competing risks and clustering: A review and synthesis	2
Approximate confidence intervals for the difference in proportions for partially observed binary data	2
Propensity score weighting methods for causal subgroup analysis with time-to-event outcomes	2
Robust regression with asymmetric loss functions	2
Directional-sum test for nonparametric Behrens-Fisher problem with applications to the dietary intervention trial	2
Covariate-adjusted inference for doubly adaptive biased coin design	2
Restricted mean survival time to estimate an intervention effect in a cluster randomized trial	2
Extended excess hazard models for spatially dependent survival data	2
Penalized variable selection in multi-parameter regression survival modeling	2
Augmenting contact matrices with time-use data for fine-grained intervention modelling of disease dynamics: A modelling analysis	2
Improving the estimation of the COVID-19 effective reproduction number using nowcasting	2
Copula graphic estimation of the survival function with dependent censoring and its application to analysis of pancreatic cancer clinical trial	2
A unified approach based on multidimensional scaling for calibration estimation in survey sampling with qualitative auxiliary information	2
Data-dependent early completion of dose-finding trials for drug-combination	2
A Bayesian approach to simultaneous adjustment of misclassification and missingness in categorical covariates	2
Modeling the patient mix for risk-adjusted CUSUM charts	2
Estimating individualized treatment rules in longitudinal studies with covariate-driven observation times	2
Resampling-based inferences for compositional regression with application to beef cattle microbiomes	2
Bivariate joint models for survival and change of cognitive function	2
Allowing for stratification in sample size planning of two-arm trials with continuous or binary outcome: Overview and tutorial	2
Modified Brier score for evaluating prediction accuracy for binary outcomes	2
Statistical methods used to combine the effective reproduction number, R(t), and other related measures of COVID-19 in the UK	2
A simple and robust parametric shared frailty model for recurrent events with the competing risk of death: An application to the Carvedilol Prospective Randomized Cumulative Survival trial	2
Bayesian inference on the number of recurrent events: A joint model of recurrence and survival	2
Functional response regression model on correlated longitudinal microbiome sequencing data	2
Optimal allocation strategies in platform trials with continuous endpoints	1
Complete effect decomposition for an arbitrary number of multiple ordered mediators with time-varying confounders: A method for generalized causal multi-mediation analysis	1
Semi-parametric testing for ordinal treatment effects in time-to-event data via dynamic Dirichlet process mixtures of the inverse-Gaussian distribution	1
Analysis of recurrent event data with spatial random effects using a Bayesian approach	1
Statistical considerations for evaluating treatment effect under various non-proportional hazard scenarios	1
Re-randomisation trials in multi-episode settings: Estimands and independence estimators	1
How to add baskets to an ongoing basket trial with information borrowing	1
Causal mediation analysis for time-to-event mediator and outcome in the presence of left truncation	1
Effect estimation in the presence of a misclassified binary mediator	1