Statistical Methods in Medical Research

Article	Citations
Exact interval estimation for the linear combination of binomial proportions	153
A Bayesian beta-binomial piecewise growth mixture model for longitudinal overdispersed binomial data	93
Omnibus test for restricted mean survival time based on influence function	77
Interval estimation in three-class receiver operating characteristic analysis: A fairly general approach based on the empirical likelihood	64
Covariate adjustment in Bayesian adaptive randomized controlled trials	35
Confidence estimation based on data from independent studies	34
Time-varying coefficient additive hazards model with latent variables	31
Equivalence tests for ratio of means in bioequivalence studies under crossover design	30
Semiparametric copula method for semi-competing risks data subject to interval censoring and left truncation: Application to disability in elderly	30
Analysis of hospital readmissions with competing risks	29
A new cure model accounting for longitudinal data and flexible patterns of hazard ratios over time	25
Joint meta-analysis of two diagnostic tests accounting for within and between studies dependence	23
Generalized Bayesian kernel machine regression	22
Commentary on the use of the reproduction number R during the COVID-19 pandemic	22
Generalised pairwise comparisons for trend: An extension to the win ratio and win odds for dose-response and prognostic variable analysis with arbitrary statements of outcome preference	21
Modeling and estimating a threshold effect: An application to improving cardiac surgery practices	20
Accounting for informative observation process in transition models of binary longitudinal outcome: Application to medical record data	20
Response-adaptive treatment randomization for multiple comparisons of treatments with recurrent event responses	19
Developing clinical prediction models when adhering to minimum sample size recommendations: The importance of quantifying bootstrap variability in tuning parameters and predictive performance	19
Analyzing heterogeneity in biomarker discriminative performance through partial time-dependent receiver operating characteristic curve modeling	19
Multiplicative versus additive modelling of causal effects using instrumental variables for survival outcomes – a comparison	18
Using shrinkage methods to estimate treatment effects in overlapping subgroups in randomized clinical trials with a time-to-event endpoint	17
New clinical trial design borrowing information across patient subgroups based on fusion-penalized regression models	17
Random survival forests with multivariate longitudinal endogenous covariates	16
On flexible inverse probability of treatment and intensity weighting: Informative censoring, variable selection, and weight trimming	16

A capture-recapture modeling framework emphasizing expert opinion in disease surveillance	16
Correlational analyses of biomarkers that are harmonized through a bridging study due to measurement errors	14
Nonparametric analysis of doubly truncated and interval-censored data	14
Augmenting contact matrices with time-use data for fine-grained intervention modelling of disease dynamics: A modelling analysis	13
Revisiting performance metrics for prediction with rare outcomes	13
Inference on the overlap coefficient: The binormal approach and alternatives	13
A family of Bayesian prognostic and predictive covariate-adjusted response-adaptive randomization designs	13
Bayesian order constrained adaptive design for phase II clinical trials evaluating subgroup-specific treatment effect	13
Challenges of modelling approaches for network meta-analysis of time-to-event outcomes in the presence of non-proportional hazards to aid decision making: Application to a melanoma network	13
Estimating a time-to-event distribution from right-truncated data in an epidemic: A review of methods	12
Inference for the treatment effect in longitudinal cluster randomized trials when treatment effect heterogeneity is ignored	12
Quantifying proportion of treatment effect by surrogate endpoint under heterogeneity	12
A unified approach based on multidimensional scaling for calibration estimation in survey sampling with qualitative auxiliary information	12
Fitting joint models of longitudinal observations and time to event by sequential Bayesian updating	11
Familywise error rate control for block response-adaptive randomization	11
Evaluating prognostic biomarkers for survival outcomes subject to informative censoring	11
Penalized variable selection in multi-parameter regression survival modeling	10
Smoothing Lexis diagrams using kernel functions: A contemporary approach	10
Modeling the patient mix for risk-adjusted CUSUM charts	10
A Bayesian genomic selection approach incorporating prior feature ordering and population structures with application to coronary artery disease	10
A simple and robust parametric shared frailty model for recurrent events with the competing risk of death: An application to the Carvedilol Prospective Randomized Cumulative Survival trial	10
Simultaneous confidence intervals for an extended Koch-Röhmel design in three-arm non-inferiority trials	10
Allowing for stratification in sample size planning of two-arm trials with continuous or binary outcome: Overview and tutorial	10
Quantification of the influence of risk factors with application to cardiovascular diseases in subjects with type 1 diabetes	9
An iterative matrix uncertainty selector for high-dimensional generalized linear models with measurement errors	9
More efficient estimators of the area under the receiver operating characteristic curve in paired ranked set sampling	9
Covariate selection for optimizing balance with an innovative adaptive randomization approach	9
Adjusting for switches to multiple treatments: Should switches be handled separately or combined?	9
Modified Brier score for evaluating prediction accuracy for binary outcomes	9
The effect of estimating prevalences on the population-wise error rate	9
Complete effect decomposition for an arbitrary number of multiple ordered mediators with time-varying confounders: A method for generalized causal multi-mediation analysis	8
Change plane model averaging for subgroup identification	8
Estimand-based inference in the presence of long-term survivors	8
Model-based adaptive randomization procedures for heteroscedasticity of treatment responses	8
Causal simulation experiments: Lessons from bias amplification	8
Using horseshoe prior for incorporating multiple historical control data in randomized controlled trials	8
Review of sample size determination methods for the intraclass correlation coefficient in the one-way analysis of variance model	8
A generalization of moderated statistics to data adaptive semiparametric estimation in high-dimensional biology	8
Sample size calculation for multi-arm parallel design with restricted mean survival time	8
On recurrent-event win ratio	8
A competing risks regression model for the association between time-varying opioid exposure and risk of overdose	7
A tight fit of the SIR dynamic epidemic model to daily cases of COVID-19 reported during the 2021–2022 Omicron surge in New York City: A novel approach	7
Hunting for protective drugs at the break of a pandemic: Causal inference from hospital data	7
MISL: Multiple imputation by super learning	7
Test sensitivity in a prospective cancer screening program: A critique of a common proxy measure	7
Regression analysis of multivariate recurrent event data allowing time-varying dependence with application to stroke registry data	7
Cause-specific hazard Cox models with partly interval censoring – Penalized likelihood estimation using Gaussian quadrature	7
Flexible extension of the accelerated failure time model to account for nonlinear and time-dependent effects of covariates on the hazard	7
Statistical methods for clinical trials interrupted by the severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) pandemic: A review	7
Testing for marginal covariate effect when the subgroup size induced by the covariate is informative	7

The analysis of COVID-19 in-hospital mortality: A competing risk approach or a cure model?	7
Space-time interactions in Bayesian disease mapping with recent tools: Making things easier for practitioners	7
qTPI: A quasi-toxicity probability interval design for phase I trials with multiple-grade toxicities	7
Improved and computationally stable estimation of relative risk regression with one binary exposure	6
Using short-term endpoints to improve interim decision making and trial duration in two-stage phase II trials with nested binary endpoints	6
Using Bayesian evidence synthesis to quantify uncertainty in population trends in smoking behaviour	6
A generalized epidemiological model with dynamic and asymptomatic population	6
Mid-quantile regression for discrete responses	6
Use of clinical tolerance limits for assessing agreement	6
A new framework for semi-Markovian parametric multi-state models with interval censoring	6
Combining multiple biomarkers linearly to minimize the Euclidean distance of the closest point on the receiver operating characteristic surface to the perfection corner in trichotomous settings	6
BOIN-ETC: A Bayesian optimal interval design considering efficacy and toxicity to identify the optimal dose combinations	6
Editorial	6
CFO: Calibration-free odds design for phase I/II clinical trials	6
Generalized fiducial inference for the restricted mean survival time	6
Interval estimation for the Youden index of a continuous diagnostic test with verification biased data	6
A Weibull mixture cure frailty model for high-dimensional covariates	6
Local linear approximation with Laplacian smoothing penalty and application in biology	6
Estimation and inference on the partial volume under the receiver operating characteristic surface	6
Simulation extrapolation method for measurement error: A review	6
Fixed and random effect selections in generalized linear mixed models	6
Comparison of statistical methods for the analysis of patient-reported outcomes in randomised controlled trials: A simulation study	6
Time-dependent receiver operating characteristic curve estimator for correlated right-censored time-to-event data	6
Adaptive enrichment trial designs using joint modelling of longitudinal and time-to-event data	6
Multiple imputation approaches for epoch-level accelerometer data in trials	6
Group lasso priors for Bayesian accelerated failure time models with left-truncated and interval-censored data	6
Estimation in discrete time coarsened multivariate longitudinal models	6
A Bayesian latent class approach to causal inference with longitudinal data	6
Estimating the sample mean and standard deviation from order statistics and sample size in meta-analysis	5
Heterogeneous treatment effect estimation for observational data using model-based forests	5
Bayesian analysis of joint quantile regression for multi-response longitudinal data with application to primary biliary cirrhosis sequential cohort study	5
Bayesian variable selection in hierarchical difference-in-differences models	5
Quantile outcome adaptive lasso: Covariate selection for inverse probability weighting estimator of quantile treatment effects	5
Unified approach to optimal estimation of mean and standard deviation from sample summaries	5
Average treatment effect on the treated, under lack of positivity	5
Distribution-free control charts for mixed-type data based on rank of interpoint distances	5
MEGH: A parametric class of general hazard models for clustered survival data	5
Bivariate copula regression models for semi-competing risks	5
Health utility adjusted survival: A composite endpoint for clinical trial designs	5
Solutions to problems of nonexistence of parameter estimates and sparse data bias in Poisson regression	5
Variance partitioning in spatio-temporal disease mapping models	5
Sample sizes required to estimate the protective efficacy of a vaccine when there is an unequal allocation of individuals across the vaccine and placebo groups	5
Additive hazards model with time-varying coefficients and imaging predictors	5
Factorial survival analysis for treatment effects under dependent censoring	5
An overview of optimal designs under a given budget in cluster randomized trials with a binary outcome	5
The change in estimate method for selecting confounders: A simulation study	5
The “Why” behind including “Y” in your imputation model	5
Semiparametric generalized estimating equations for repeated measurements in cross-over designs	5
Using circulating tumor DNA as a novel biomarker of efficacy for dose-finding designs in oncology	5
Unbiased and robust analysis of co-localization in super-resolution images	5
Data-driven clustering of infectious disease incidence into age groups	5
Group sequential analysis of marked point processes: Plasma donation trials	5
Divided-and-combined omnibus test for genetic association analysis with high-dimensional data	5
An objective Bayesian approach to estimation in multistage experiments	5
Bivariate joint models for survival and change of cognitive function	4
Clustering functional data using forward search based on functional spatial ranks with medical applications	4
A new measure to quantify sedentary behavior using accelerometer data: Application to the Hispanic Community Health Study/Study of Latinos	4
Regularization approaches in clinical biostatistics: A review of methods and their applications	4
A distribution-free smoothed combination method to improve discrimination accuracy in multi-category classification	4
Biomarker-driven optimal designs for patient enrollment restriction	4
Isotonic design for single-arm biomarker stratified trials	4
Jointly assessing multiple endpoints in pilot and feasibility studies	4
Graphical methods to illustrate the nature of the relation between a continuous variable and the outcome when using restricted cubic splines with a Cox proportional hazards model	4
Causal rule ensemble method for estimating heterogeneous treatment effect with consideration of prognostic effects	4
Comparisons of various estimates of the I2 statistic for quantifying between-study heterogeneity in meta-analysis	4
Extended excess hazard models for spatially dependent survival data	4
Variable selection with missing data in both covariates and outcomes: Imputation and machine learning	4
Strategies to boost statistical efficiency in randomized oncology trials with primary time-to-event endpoints	4
Model detection for semiparametric accelerated failure additive model with right-censored data	4
Efficient algorithms for survival data with multiple outcomes using the frailty model	4
Sample size determination for adaptive crossover trial in detecting gene-drug interactions	4
Simulating time-to-event data subject to competing risks and clustering: A review and synthesis	4
LASSO-type instrumental variable selection methods with an application to Mendelian randomization	4
Methods for comparative effectiveness based on time to confirmed disability progression with irregular observations in multiple sclerosis	4
A comparison of various aggregation functions in multi-criteria decision analysis for drug benefit–risk assessment	4
Covariate-adjusted inference for doubly adaptive biased coin design	4
Measuring the individualization potential of treatment individualization rules: Application to rules built with a new parametric interaction model for parallel-group clinical trials	4
Wilcoxon rank-sum tests to detect one-sided mixture alternatives in group sequential clinical trials	3
Modeling treatment effect modification in multidrug-resistant tuberculosis in an individual patientdata meta-analysis	3
A natural history and copula-based joint model for regional and distant breast cancer metastasis	3

Paired count regressions for modeling the number of doctor consultations and non-prescribed drugs intake	3
Authors’ response	3
Cross-validation approaches for penalized Cox regression	3
Improving estimation efficiency of case-cohort studies with interval-censored failure time data	3
Considerations on the region of interest in the ROC space	3
Weighting methods for truncation by death in cluster-randomized trials	3
Adaptive aggregation for longitudinal quantile regression based on censored history process	3
Comparison of random forest methods for conditional average treatment effect estimation with a continuous treatment	3
Bayesian semiparametric joint modeling of a count outcome and inconveniently timed longitudinal predictors	3
Efficient estimation of the marginal mean of recurrent events in randomized controlled trials	3
A Bayesian hierarchical model for the analysis of visual analogue scaling tasks	3
Does it decay? Obtaining decaying correlation parameter values from previously analysed cluster randomised trials	3
Exponentially weighed moving average charts for monitoring zero-inflated proportions with applications in health care	3
Online control of the False Discovery Rate in group-sequential platform trials	3
Uniformization and bounded Taylor series in Newton–Raphson method improves computational performance for a multistate transition model estimation and inference	3
Optimal allocation to treatments in a sequential multiple assignment randomized trial	3
An efficient approach for optimizing the cost-effective individualized treatment rule using conditional random forest	3
Multiple imputation analysis for propensity score matching with missing causes of failure: An application to hepatocellular carcinoma data	3
Nonparametric Bayesian functional selection in 1-M matched case-crossover studies	3
Intervention treatment distributions that depend on the observed treatment process and model double robustness in causal survival analysis	3
Modified interactive Q-learning for attenuating the impact of model misspecification with treatment effect heterogeneity	3
Estimating dynamic treatment regimes for ordinal outcomes with household interference: Application in household smoking cessation	3
Variable selection for mixed panel count data under the proportional mean model	3
Conditional copula models for correlated survival endpoints: Individual patient data meta-analysis of randomized controlled trials	3
Multicategory matched learning for estimating optimal individualized treatment rules in observational studies with application to a hepatocellular carcinoma study	3
Using information criteria to select smoothing parameters when analyzing survival data with time-varying coefficient hazard models	3
Semi-parametric testing for ordinal treatment effects in time-to-event data via dynamic Dirichlet process mixtures of the inverse-Gaussian distribution	3
Optimising error rates in programmes of pilot and definitive trials using Bayesian statistical decision theory	3
Fitting to the UK COVID-19 outbreak, short-term forecasts and estimating the reproductive number	3
Mean corrected generalized estimating equations for longitudinal binary outcomes with report bias	3
Novel empirical likelihood inference for the mean difference with right-censored data	3
Integrating relative survival in multi-state models—a non-parametric approach	3
On estimating a constrained bivariate random effects model for meta-analysis of test accuracy studies	3
Multivariate contaminated normal linear mixed models applied to Alzheimer’s disease study with censored and missing data	3
A statistical framework for planning and analysing test–retest studies of repeatability	3
Youden index estimation based on group-tested data	3
Determination of correlations in multivariate count data with informative observation times	2
Cure models with adaptive activation for modeling cancer survival	2
ROSIE: RObust Sparse ensemble for outlIEr detection and gene selection in cancer omics data	2
The performance of marginal structural models for estimating risk differences and relative risks using weighted univariate generalized linear models	2
Multiple imputation for cause-specific Cox models: Assessing methods for estimation and prediction	2
Partly linear single-index cure models with a nonparametric incidence link function	2
Rank-based estimators of global treatment effects for cluster randomized trials with multiple endpoints on different scales	2
An overview of propensity score matching methods for clustered data	2
Dirichlet process mixture models for regression discontinuity designs	2
Variable selection using inverse probability of censoring weighting	2
Penalized estimation for varying coefficient additive hazards models	2
Hierarchical Bayesian bivariate spatial modeling of small area proportions with application to health survey data	2
Boosting distributional copula regression for bivariate binary, discrete and mixed responses	2
A functional proportional hazard cure rate model for interval-censored data	2
Matching ratio and sample size for optimal sequential testing with binomial data	2
Estimation of the average treatment effect with variable selection and measurement error simultaneously addressed for potential confounders	2
Bayesian multiple Gaussian graphical models for multilevel variables from unknown classes	2
Assigning readers to cases in imaging studies using balanced incomplete block designs	2
Conversion of non-inferiority margin from hazard ratio to restricted mean survival time difference using data from multiple historical trials	2
Doubly-robust estimator of the difference in restricted mean times lost with competing risks data	2
Refined moderation analysis with binary outcomes in precision medicine research	2
Saddlepoint approximation p-values of weighted log-rank tests based on censored clustered data under block Efron’s biased-coin design	2
Dealing with missing information on covariates for excess mortality hazard regression models – Making the imputation model compatible with the substantive model	2
Methods for non-proportional hazards in clinical trials: A systematic review	2
Group sequential methods based on supremum logrank statistics under proportional and nonproportional hazards	2
Nonparametric Bayesian Q-learning for optimization of dynamic treatment regimes in the presence of partial compliance	2
Multivariate control charts for monitoring a bivariate correlated count process with application to meningococcal disease	2
On estimating the area under the ROC curve in ranked set sampling	2
Sample size estimation for comparing dynamic treatment regimens in a SMART: A Monte Carlo-based approach and case study with longitudinal overdispersed count outcomes	2
On the estimation of population size—A comparison of capture-recapture and multiplier-benchmark methods	2
Estimating transformations for evaluating diagnostic tests with covariate adjustment	2
Evaluations of the sum-score-based and item response theory-based tests of group mean differences under various simulation conditions	2
Joint regression analysis of clustered current status data with latent variables	2
Stopping rules for phase I clinical trials with dose expansion cohorts	2
A model-based approach for historical borrowing, with an application to neovascular age-related macular degeneration	2
Point estimation of the 100p percent lethal dose using a novel penalised likelihood approach	2
Unit information prior for incorporating real-world evidence into randomized controlled trials	2
Model-based approach for two-stage group sequential or adaptive designs in bioequivalence studies using parallel and crossover designs	2
Marginal semiparametric accelerated failure time cure model for clustered survival data	2
Propensity score weighting methods for causal subgroup analysis with time-to-event outcomes	2
Logistic regression with correlated measurement error and misclassification in covariates	2
Compositional functional regression and isotemporal substitution analysis: Methods and application in time-use epidemiology	2
Using joint models for longitudinal and time-to-event data to investigate the causal effect of salvage therapy after prostatectomy	2
A matching-based machine learning approach to estimating optimal dynamic treatment regimes with time-to-event outcomes	2
Partial areas under the curve of the cumulative distribution function as a new composite estimand for randomized clinical trials	2
Response adaptive randomisation in clinical trials: Current practice, gaps and future directions	2
Two-stage subsampling variable selection for sparse high-dimensional generalized linear models	2
Shared parameter and copula models for analysis of semicontinuous longitudinal data with nonrandom dropout and informative censoring	2
Data-dependent early completion of dose-finding trials for drug-combination	2
A family of estimators to diagnostic accuracy when candidate tests are subject to detection limits—Application to diagnosing early stage Alzheimer disease	2
Estimating latent, dynamic processes of breast cancer tumour growth and distant metastatic spread from mammography screening data	2
A class of two-sample nonparametric statistics for binary and time-to-event outcomes	2
A novel rare variants association test for binary traits in family-based designs via copulas	2
A survival mediation model with Bayesian model averaging	2
Instrumental variable analysis with categorical treatment	2
A novel power prior approach for borrowing historical control data in clinical trials	2
Adaptive group sequential survival comparisons based on log-rank and pointwise test statistics	2
Causal mediation analysis with multiple causally non-ordered and ordered mediators based on summarized genetic data	2
Nonparametric kernel estimation of the probability of cure in a mixture cure model when the cure status is partially observed	1