Trends in Cell Biology

Article	Citations
Advisory Board and Contents	436
(Alternative) transcription start sites as regulators of RNA processing	308
HELLS: the transcriptional sentinel	268
An ATM D-compartmentalization in DNA damage response	246
DNA-PKcs kinase activity orchestrates both end-processing and end-ligation	201
Modulating cell-free DNA biology as the next frontier in liquid biopsies	195
The postdoctoral blueprint part one: creating a niche	186
Translation is an emerging constraint on protein homeostasis in ageing	153
Unlocking Latin America´s scientific potential: challenges and opportunities in a globalized world	143
Plasticity of cancer invasion and energy metabolism	140
Centrosomes and cancer: balancing tumor-promoting and inhibitory roles	140
The bidirectional relationship between metabolism and cell cycle control	137
Subscription and Copyright Information	137
Advisory Board and Contents	135
Subscription and Copyright Information	135
Optical tweezers across scales in cell biology	123
A glitch in the matrix: organ-specific matrisomes in metastatic niches	123
The multifaceted mitochondrial OXA insertase	115
Opportunities and challenges for deep learning in cell dynamics research	111
Where protein structure and cell diversity meet	109
Bucket lists must be completed during cell death	98
Regulation of lipid droplet dynamics and lipid homeostasis by hydroxysteroid dehydrogenase proteins	97
Primary ciliary signaling: links with the cell cycle	95
Olfaction: an emerging regulator of longevity and metabolism	93
Cytoplasmic mtDNA clearance suppresses inflammatory immune responses	92

DDX47 untangles R-loops with only certain other helicases	91
Subscription and Copyright Information	91
POGK is a domesticated KRAB domain-containing transposable element with tumor suppressive functions in breast cancer	88
Progress and limitations in engineering cellular adhesion for research and therapeutics	85
Bioelectric regulation of intestinal stem cells	83
Diverse routes to mitophagy governed by ubiquitylation and mitochondrial import	80
Sublethal engagement of apoptotic pathways in residual cancer	78
Deciphering the significance of p53 mutant proteins	78
Cultured meat: creative solutions for a cell biological problem	74
Interphase microtubules in nuclear organization and genome maintenance	74
Lessons in longevity from blood stem cells under protein stress	74
Multifaceted mitochondrial quality control in brown adipose tissue	72
The emergence of the stem cell niche	70
tRNA modifications: insights into their role in human cancers	69
Advisory Board and Contents	69
Subscription and Copyright Information	68
Built to last: lysosome remodeling and repair in health and disease	67
Shared genetic and epigenetic changes link aging and cancer	66
Moonlighting translation factors: multifunctionality drives diverse gene regulation	65
Reimagining journal clubs for inclusive scientific training	64
Visualizing intracellular target antigens in live cells	64
Tumor–stromal metabolic crosstalk in pancreatic cancer	64
Endoplasmic reticulum (ER) protein degradation by ER-associated degradation and ER-phagy	63
Accessible high-speed image-activated cell sorting	63
Biomolecular condensates: hubs of Hippo-YAP/TAZ signaling in cancer	61
Self-inflicted DNA breaks in cell differentiation and cancer	60
Reprogramming transcription after DNA damage: recognition, response, repair, and restart	59
Wnt signalling in cell division: from mechanisms to tissue engineering	58
Young researchers series #3	58
Subscription and Copyright Information	58
Advisory Board and Contents	57
Young researchers series #7	57
Young researchers series #3	57
Meiotic spindle pushed outward by inward organelle packing	56
Fun in the sun: ribosomes defend against UV irradiation	56
Filopodia: integrating cellular functions with theoretical models	56
Principles of membrane remodeling by dynamic ESCRT-III polymers	56
Embryos burn fat in standby	52
Advisory Board and Contents	52
Advisory Board and Contents	51
Transcription-coupled repair of DNA–protein crosslinks	51
Intravital and high-content multiplex imaging of the immune system	51
Unique architectural features of mammalian mitochondrial protein synthesis	50
ERMCS Ca2+ transmission fuels cell division	50
Telomere dynamics as mediators of gut microbiota–host interactions	50
Revealing new biology from multiplexed, metal-isotope-tagged, single-cell readouts	48
Thermoporter: a new regulatory mechanism for mitochondrial calcium uniporter activity	48
Lysosomal functions of progranulin and implications for treatment of frontotemporal dementia	47
Targeting SHP1 and SHP2 to suppress tumors and enhance immunosurveillance	46
Differentiation of the tumor microenvironment: are CAFs the Organizer?	46

Membrane remodeling and trafficking piloted by SARS-CoV-2	45
Putative homeostatic role of cancer driver mutations	44
Mechanical communication in fibrosis progression	44
Advisory Board and Contents	42
Subscription and Copyright Information	42
Orientational cell adhesions (OCAs) for tissue morphogenesis	41
Advisory Board and Contents	41
ER: a critical hub for STING signaling regulation	41
Order from chaos: cellular asymmetries explained with modelling	40
Chaperone networks are shaped by cellular differentiation and identity	40
The idiosyncrasies of oocytes	40
Cell cycle regulation by the ribotoxic stress response	40
Phase separation on microtubules: from droplet formation to cellular function?	39
Modulation of membrane–cytoskeleton interactions: ezrin as key player	39
Young researchers series #6	39
Increased O-GlcNAcylation connects metabolic to transcriptional reprogramming during pathophysiological cell activation	39
Oxidative DNA damage and repair at non-coding regulatory regions	39
Disruption of lineage integrity as a precursor to breast tumor initiation	38
Bloodhounds chasing the origin of blood cells	38
Cellular mechanics during division of a genomically minimal cell	38
Versatility of gasdermin D beyond pyroptosis	38
The amoeboid state as part of the epithelial-to-mesenchymal transition programme	37
Mechanical regulation of cell-cycle progression and division	37
Patterns in the tapestry of chromatin-bound RB	37
Sugar symphony: glycosylation in cancer metabolism and stemness	36
Advisory Board and Contents	35
Regulation of gene expression by glycolytic and gluconeogenic enzymes	35
Advisory Board and Contents	35
Subscription and Copyright Information	35
Subscription and Copyright Information	35
Lysosomal enzyme trafficking: from molecular mechanisms to human diseases	35
Subscription and Copyright Information	34
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Creating inclusive environments in cell biology by casual mentoring	33
Spatiotemporal dynamic regulation of membraneless organelles by chaperone networks	33
New job for an old tool: PI3Kβ phosphorylates OGT to regulate acetyl-CoA in glioblastoma	33
Extracellular vesicle-mediated crosstalk in tumor microenvironment dominates tumor fate	32
The neuronal-like behaviour of macrophages	30
Hidden protein functions and what they may teach us	30
The peroxisome: an up-and-coming organelle in immunometabolism	30
Immune surveillance of senescence: potential application to age-related diseases	30
The adipocyte supersystem of insulin and cAMP signaling	29
Death by ribosome	29
Hierarchical folding of the catalytic core during mitochondrial ribosome biogenesis	29
Stress relief: emerging methods to mitigate dissociation-induced artefacts	29
Spermidine – an old molecule with a new age-defying immune function	29
Redefining actin dynamics of the pointed-end complex in striated muscle	28
ER remodeling via lipid metabolism	28
Stress-induced cell depolarization through the MAP kinase–Cdc42 axis	28
Advisory Board and Contents	28
Young researchers series #2	28
The epigenetic landscape of mesenchymal stem cell and extracellular vesicle therapy	27
The many faces of H3.3 in regulating chromatin in embryonic stem cells and beyond	27
The Cys/N-degron pathway in the ubiquitin–proteasome system and autophagy	27
Muscle is a stage, and cells and factors are merely players	26
CS proteins and ubiquitination: orchestrating DNA repair with transcription and cell division	26
Quality control of mitochondrial nucleoids	26
Changing the culture for the future: time to take brain drain in academics seriously	26
The ubiquitin–proteasome system links NADPH metabolism to ferroptosis	26
Advisory Board and Contents	25
Calcium homeostasis and cancer: insights from endoplasmic reticulum-centered organelle communications	25
Advisory Board and Contents	25
Phase separation of p62: roles and regulations in autophagy	24
Chromatin-interacting RNA-binding proteins regulate transcription	24
Tumor-initiating cells establish a niche to overcome isolation stress	24
Regulated circRNA nuclear export in neuronal differentiation	24
Molecular mechanisms of nucleolar DNA damage checkpoint response	24
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3′UTR heterogeneity and cancer progression	24
Glucose metabolism of TAMs in tumor chemoresistance and metastasis	23
The heterogeneity of cellular senescence: insights at the single-cell level	23
The Warburg effect: a signature of mitochondrial overload	23
Metabolic regulation of mRNA splicing	23
Emerging roles of intratumor microbiota in cancer metastasis	23
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Advisory Board and Contents	22
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Chromatin dynamics in human brain development and disease	22
Hard to handle: how lipid saturation affects the nuclear envelope	22
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Technological and computational advances driving high-throughput oncology	21
ATRX loss induces lineage plasticity and squamous-like phenotype to promote colorectal cancer metastasis	21
A stable start: cotranslational Nt-acetylation promotes proteome stability across kingdoms	21
Time matters: the dynamics of plasma membrane repair	21
Regulation of leukemogenesis via redox metabolism	21
Decoding human cardiovascular development and disease through single-cell transcriptomic and epigenomic profiling	21
The autophagy–NAD axis in longevity and disease	20
TFEB links the cGAS-STING pathway to lysosome biogenesis	20
DNA single-strand break repair and human genetic disease	20
Novel imaging methods and force probes for molecular mechanobiology of cytoskeleton and adhesion	20
Mitotic disassembly and reassembly of nuclear pore complexes	20
The two sides of creatine in cancer	20
Extracellular vesicles from the dead: the final message	20
Fumarate hydratase as a metabolic regulator of immunity	20
RNA G-quadruplexes and stress: emerging mechanisms and functions	20
Multifaceted collagen-DDR1 signaling in cancer	19
Subscription and Copyright Information	19
Fracture in living tissues	19
Nucleus segmentation: towards automated solutions	18
Bivalent recognition of histone marks by BARD1	18
Celebrating 35 years of Trends in Cell Biology and introducing our special issue on ribosomal dynamics and cellular homeostasis	18
Primordial super-enhancers: heat shock-induced chromatin organization in yeast	17
The role of the immune tumor microenvironment in shaping metastatic dissemination, dormancy, and outgrowth	17
Ferroptosis: mechanisms and implications for cancer development and therapy response	17
How pervasive are post-translational and -transcriptional modifications?	17
Cyclin E in normal physiology and disease states	17
Mechanism-aware and multimodal AI: beyond model-agnostic interpretation	17
Glucagon-producing α-cell transcriptional identity and reprogramming towards insulin production	17
DNA replication: the recombination connection	16
Advancing cell biology with nanoscale fluorescence imaging: essential practical considerations	16
Hypoxia-specific transcriptional condensates drive metastasis	16
Clonal hematopoiesis and inflammation – the perpetual cycle	16
Unfolding by Cdc48/p97: different strokes for different folks	16
Advisory Board and Contents	16
The enigmatic roles of epithelial gasdermin B: Recent discoveries and controversies	16
Implementing standardized diversity, equity, and inclusion approaches within scientific communities	16
Extracellular matrix remodeling facilitates obesity-associated cancer progression	15
The initiation of mammalian embryonic transcription: to begin at the beginning	15
Degradation of nuclear components via different autophagy pathways	15
Reflected stemness as a potential driver of the tumour microenvironment	15
A novel superfamily of bridge-like lipid transfer proteins	15
Subscription and Copyright Information	14
The role of RAS oncogenes in controlling epithelial mechanics	14
Inter-membrane control of junctional InsP3 receptors by PIP2	14
Multiplicity of stem cell memories of inflammation and tissue repair in epithelia	14
Mitochondrial substrate oxidation regulates distinct cell differentiation outcomes	14
Mechanisms of cellular mRNA transcript homeostasis	14
Spotlighting adult stem cells: advances, pitfalls, and challenges	14
NADH reductive stress drives metabolic reprogramming	13
Time as a danger signal promoting G1 arrest after mitosis	13
Experimental evolution for cell biology	13
CDK11, a splicing-associated kinase regulating gene expression	13
Coordinated in confined migration: crosstalk between the nucleus and ion channel-mediated mechanosensation	13
3D genome folding in epigenetic regulation and cellular memory	13
Newly identified cell types crucial for gut commensal tolerance	13
MDM4 exon skipping upon dysfunctional ribosome assembly	12
The culture and application of circulating tumor cell-derived organoids	12
Lysosomal microautophagy: an emerging dimension in mammalian autophagy	12
Vimentin at the core of wound healing	12
miRNA dosage control in development and human disease	12
PYK2, a hub of signaling networks in breast cancer progression	12
The cell biology of APOE in the brain	11
Advisory Board and Contents	11
Is clathrin a membrane fission protein?	11
Cellular plasticity in reprogramming, rejuvenation and tumorigenesis: a pioneer TF perspective	11
Mechanobiology of organelles: illuminating their roles in mechanosensing and mechanotransduction	11
Triple threat: neutrophil ER stress, NETosis, airway inflammation escalation	11
Tau liquid–liquid phase separation in neurodegenerative diseases	11
Roles of YAP/TAZ in ferroptosis	11
Plasma membrane damage is a new trigger of cellular senescence	11
Experimental tools and emerging principles of organellar mechanotransduction	11
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Transsulfuration, minor player or crucial for cysteine homeostasis in cancer	10
Arming a killer: mitochondrial regulation of CD8+ T cell cytotoxicity	10
Central role of the ER proteostasis network in healthy aging	10
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Metabolic and epigenetic regulation of endoderm differentiation	10
Cell cycle on the crossroad of tumorigenesis and cancer therapy	10
The ins-and-outs of exosome biogenesis, secretion, and internalization	10
Gasdermins gone wild: new roles for GSDMs in regulating cellular homeostasis	10
Regulatory landscape of enhancer-mediated transcriptional activation	10
Emerging roles of olfactory receptors in glucose metabolism	10
Autophagosomal components recycling on autolysosomes	9
Towards solving the mystery of peroxisomal matrix protein import	9
Phenotypic plasticity during metastatic colonization	9
Metabolism and mRNA translation: a nexus of cancer plasticity	9
Integrating mechanical signals into cellular identity	9
Metabolism and HSC fate: what NADPH is made for	9
Is euchromatin really open in the cell?	9
Advisory Board and Contents	8
Advisory Board and Contents	8
Role of lipids in interorganelle communication	8
Advisory Board and Contents	8
The yin and yang of nuclear envelope breakdown through the activity of phosphatase holoenzyme PP2A-B55SUR-6	8
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