Trends in Cell Biology

Papers
(The median citation count of Trends in Cell Biology is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)
ArticleCitations
Advisory Board and Contents329
Regulation of lipid droplet dynamics and lipid homeostasis by hydroxysteroid dehydrogenase proteins238
Advisory Board and Contents216
HELLS: the transcriptional sentinel206
Single cell lipid biology175
Structural insights into actin filament turnover161
Modulating cell-free DNA biology as the next frontier in liquid biopsies130
Mitochondrial substrate oxidation regulates distinct cell differentiation outcomes127
Universities should standardize faculty application process119
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Reflected stemness as a potential driver of the tumour microenvironment116
Decoding melanoma’s cellular mosaic to unlock immunotherapy potential114
Implementing standardized diversity, equity, and inclusion approaches within scientific communities110
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Extracellular matrix remodeling facilitates obesity-associated cancer progression109
Getting sharper: the brain under the spotlight of super-resolution microscopy108
A long look at short prokaryotic Argonautes107
Advisory Board and Contents100
Advisory Board and Contents99
Intracellular phase separation and its role in nickel sensing99
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The ciliary impact of nonciliary gene mutations95
WNT-Regulated Transcriptional Enhancers and Stem Cell Plasticity91
Mechanobiological approaches to synthetic morphogenesis: learning by building88
Advisory Board and Contents86
Advisory Board and Contents83
Disruption of lineage integrity as a precursor to breast tumor initiation83
Hunger brings down the tumor fort81
An ATM D-compartmentalization in DNA damage response80
Young researchers series #679
Cancer takes many paths through G1/S76
Advisory Board and Contents75
Advisory Board and Contents74
Changing places: Chromosomal Passenger Complex relocation in early anaphase73
Metabolic immunity against microbes73
Advisory Board and Contents72
Degradation of nuclear components via different autophagy pathways67
Targeting the ubiquitin proteasome system in cancer stem cells67
Advisory Board and Contents67
Versatility of gasdermin D beyond pyroptosis65
A20: a jack of all trades65
Tetraspanins in cell stemness and cancer initiation: markers or active players?63
Spotlighting adult stem cells: advances, pitfalls, and challenges63
Contribution of metabolic abnormalities to acute myeloid leukemia pathogenesis63
Long-lived mitochondrial proteins and why they exist62
Beyond keratinocyte differentiation: emerging new biology of small proline-rich proteins61
Role of N7-methylguanosine (m7G) in cancer61
Multiplicity of stem cell memories of inflammation and tissue repair in epithelia61
The enigmatic roles of epithelial gasdermin B: Recent discoveries and controversies60
Chromosome compartmentalization: causes, changes, consequences, and conundrums59
Patterns in the tapestry of chromatin-bound RB58
Epithelial metabolism as a rheostat for intestinal inflammation and malignancy57
Lighting ATR/Chk1 by mesoscale TopBP1 condensates56
Sugar symphony: glycosylation in cancer metabolism and stemness53
Cohesin: behind dynamic genome topology and gene expression reprogramming53
Alternative careers at the autophagy factory51
Polycomb repressive complex 2 in the driver’s seat of childhood and young adult brain tumours51
Coordination between Transport and Local Translation in Neurons51
Elucidating Protein Translocon Dynamics with Single-Molecule Precision51
Cancer Physical Hallmarks as New Targets for Improved Immunotherapy50
BRCA2 in mammalian meiosis50
Fine-tuning ALK1 linear polyubiquitination to control angiogenesis48
To fit or not to fit: death decisions from morphogen fields48
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Unfolding by Cdc48/p97: different strokes for different folks47
Membrane Protein Quality Control Mechanisms in the Endo-Lysosome System47
The postdoctoral blueprint part one: creating a niche46
The role of RAS oncogenes in controlling epithelial mechanics46
Autophagy-dependent versus autophagy-independent ferroptosis46
Design principles of gene circuits for longevity45
Rewiring cell signalling pathways in pathogenic mtDNA mutations45
Cellular mechanics during division of a genomically minimal cell45
The uncharted territory of NAD+-capped RNA45
The amoeboid state as part of the epithelial-to-mesenchymal transition programme44
Mitochondrial complexome and import network44
DNA-PKcs kinase activity orchestrates both end-processing and end-ligation44
The transcription factor code: a beacon for histone methyltransferase docking43
Mechanisms of cellular mRNA transcript homeostasis43
The initiation of mammalian embryonic transcription: to begin at the beginning43
(Alternative) transcription start sites as regulators of RNA processing43
Translation is an emerging constraint on protein homeostasis in ageing42
Bidirectional communication in oogenesis: a dynamic conversation in mice and Drosophila41
The elegant complexity of mammalian ecto-5′-nucleotidase (CD73)40
Mechanical regulation of cell-cycle progression and division39
The bidirectional relationship between metabolism and cell cycle control39
Regulation of gene expression by glycolytic and gluconeogenic enzymes39
LncRNAs in human cancers: signal from noise38
Forward programming human pluripotent stem cells into microglia38
Lysosomal enzyme trafficking: from molecular mechanisms to human diseases37
Plasticity of cancer invasion and energy metabolism37
p53 and Tumor Suppression: It Takes a Network37
A novel superfamily of bridge-like lipid transfer proteins37
Nucleation, stabilization, and disassembly of branched actin networks36
Targeting ferroptosis to treat colorectal cancer36
REV7 directs DNA repair pathway choice36
Membrane curvature as a signal to ensure robustness of diverse cellular processes36
Pericytes in the disease spotlight36
Cell–3D matrix interactions: recent advances and opportunities36
Extracellular vesicles and nanoparticles: emerging complexities35
Lysosomal quality control: molecular mechanisms and therapeutic implications33
Deep learning in image-based phenotypic drug discovery32
Metabolic control of replisome plasticity in genome surveillance32
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Young researchers series #930
Advisory Board and Contents29
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Advisory Board and Contents28
Extracellular vesicle-mediated crosstalk in tumor microenvironment dominates tumor fate28
Advisory Board and Contents28
GABAergic signaling beyond synapses: an emerging target for cancer therapy28
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Newly identified cell types crucial for gut commensal tolerance27
Immune surveillance of senescence: potential application to age-related diseases27
Inosine: novel activator of brown adipose tissue and energy homeostasis27
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The culture and application of circulating tumor cell-derived organoids26
Advisory Board and Contents26
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Advisory Board and Contents26
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Gaining wisdom from enduring inequities25
Next-generation engineered microsystems for cell biology: a systems-level roadmap24
Advisory Board and Contents24
Hierarchical folding of the catalytic core during mitochondrial ribosome biogenesis24
Experimental evolution for cell biology24
The interplay of the circadian clock and metabolic tumorigenesis24
Creating inclusive environments in cell biology by casual mentoring24
Advisory Board and Contents24
Subscription and Copyright Information24
Optical tweezers across scales in cell biology23
ATG4: More Than a Protease?23
Primary ciliary signaling: links with the cell cycle23
Spatiotemporal dynamic regulation of membraneless organelles by chaperone networks23
Hidden protein functions and what they may teach us22
Bucket lists must be completed during cell death22
Mitochondria in cancer: clean windmills or stressed tinkerers?22
A glitch in the matrix: organ-specific matrisomes in metastatic niches22
Where protein structure and cell diversity meet22
Stray self-nucleic acids: the emerging drivers of neurodegeneration21
A new time dimension in the fight against metastasis21
Olfaction: an emerging regulator of longevity and metabolism21
CHRNA2: a new paradigm in beige thermoregulation and metabolism21
CDK11, a splicing-associated kinase regulating gene expression20
MDM4 exon skipping upon dysfunctional ribosome assembly20
Inter-membrane control of junctional InsP3 receptors by PIP220
Advancements in kidney organoids and tubuloids to study (dys)function20
Putting transcriptional brakes on fibrosis: a negative regulator of TGFβ signaling20
RNA m6A methylation at the juxtaposition of apoptosis and RNA therapeutics20
Structural perspectives on transcription in chromatin20
Autocrine amphiregulin signaling sustains castration-resistant Ly6d+ prostate cancer cells20
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Experimental manipulation of phosphoinositide lipids: from cells to organisms19
Cytoplasmic mtDNA clearance suppresses inflammatory immune responses19
Protecting the future: balancing proteostasis for reproduction19
3D gastruloids: a novel frontier in stem cell-based in vitro modeling of mammalian gastrulation19
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Death by ribosome19
Vimentin at the core of wound healing19
Advisory Board and Contents18
Regulation of lipid droplet dynamics and lipid homeostasis by hydroxysteroid dehydrogenase proteins18
Rhythmic forces shaping the zebrafish cardiac system18
Cellular plasticity in reprogramming, rejuvenation and tumorigenesis: a pioneer TF perspective17
Lipids and chromatin: a tale of intriguing connections shaping genomic landscapes17
Reacting to reductive stress at the mitochondrial import gate17
Leveraging computational modeling to explore epithelial and endothelial cell monolayer mechanobiology17
Mechanobiology of organelles: illuminating their roles in mechanosensing and mechanotransduction17
Lysosomal microautophagy: an emerging dimension in mammalian autophagy16
Modulation of extrinsic apoptotic pathway by intracellular glycosylation16
The peroxisome: an up-and-coming organelle in immunometabolism16
Phase separation in genome organization across evolution16
Tau liquid–liquid phase separation in neurodegenerative diseases16
Coordinated in confined migration: crosstalk between the nucleus and ion channel-mediated mechanosensation16
The adipocyte supersystem of insulin and cAMP signaling16
Unlocking mechanosensitivity: integrins in neural adaptation16
PYK2, a hub of signaling networks in breast cancer progression16
The multifaceted mitochondrial OXA insertase16
Stress relief: emerging methods to mitigate dissociation-induced artefacts16
Spermidine – an old molecule with a new age-defying immune function16
Epigenetic regulation of hematopoietic stem cell fate15
The cell biology of APOE in the brain15
Opportunities and challenges for deep learning in cell dynamics research15
Roles of YAP/TAZ in ferroptosis15
Cellular mechanisms of connexin-based inherited diseases15
Translational control of papillomavirus mRNAs in the spotlight15
RNA polymerase III directly participates in DNA homologous recombination15
Crosstalk between gut microbiota and cellular senescence: a vicious cycle leading to aging gut15
New Insights into CDK Regulators: Novel Opportunities for Cancer Therapy15
Non-canonical mTORC1 signaling at the lysosome15
miRNA dosage control in development and human disease14
Interplay between hormonal and mechanical signals in mammary morphodynamics14
Sirtuin 6: linking longevity with genome and epigenome stability14
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Metabolic and epigenetic regulation of endoderm differentiation14
Muscle Stem Cell Quiescence: Controlling Stemness by Staying Asleep14
Tetraspanins: structure, dynamics, and principles of partner-protein recognition14
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Advisory Board and Contents13
Young researchers series #213
SAi: an experimental incubator for informal science learning initiatives13
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Young researchers series #513
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Advisory Board and Contents13
Mechanical activation of mitochondria in germ cell differentiation12
Advisory Board and Contents12
Redefining actin dynamics of the pointed-end complex in striated muscle12
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Advisory Board and Contents12
Regulatory landscape of enhancer-mediated transcriptional activation12
Microbial metabolites: novel therapeutic tools for boosting cancer therapies12
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Chromatin basis of the senescence-associated secretory phenotype12
Enteric glia: genomically open, poised, and ready to make neurons11
Stress-induced cell depolarization through the MAP kinase–Cdc42 axis11
Functional analysis of cell plasticity using single-cell technologies11
DDX47 untangles R-loops with only certain other helicases11
The emerging role of receptor tyrosine kinase phase separation in cancer11
NIPBL and cohesin: new take on a classic tale11
Phenotypic noise and plasticity in cancer evolution10
Multifaceted mitochondrial quality control in brown adipose tissue10
Peroxisomes are underappreciated organelles hijacked by viruses10
POGK is a domesticated KRAB domain-containing transposable element with tumor suppressive functions in breast cancer10
Glial plasticity in the zebrafish central nervous system10
Age-associated changes in transcriptional elongation and their effects on homeostasis10
Plasma membrane damage is a new trigger of cellular senescence10
Proteome-wide CETSA reveals new step in apoptosis control10
Mitochondrial regulation in stem cells10
ER remodeling via lipid metabolism10
Triple threat: neutrophil ER stress, NETosis, airway inflammation escalation9
Transcription-Coupled DNA Repair: From Mechanism to Human Disorder9
Changing the culture for the future: time to take brain drain in academics seriously9
Central role of the ER proteostasis network in healthy aging9
Cultured meat: creative solutions for a cell biological problem9
Nonredundant Rac-GEF control of actin cytoskeleton reorganization9
A Destiny for Degradation: Interplay between Cullin-RING E3 Ligases and Autophagy9
Diverse routes to mitophagy governed by ubiquitylation and mitochondrial import9
Mitochondrial DNA Dynamics in Reprogramming to Pluripotency8
Deciphering the significance of p53 mutant proteins8
Sublethal engagement of apoptotic pathways in residual cancer8
Advisory Board and Contents8
How are mitochondrial nucleoids trafficked?8
Dedifferentiation of Epithelial Cells Incorporates Immune Reprogramming8
CS proteins and ubiquitination: orchestrating DNA repair with transcription and cell division8
Quality control of mitochondrial nucleoids8
Rigidity transitions in development and disease8
Bioelectric regulation of intestinal stem cells8
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