Trends in Cell Biology

Article	Citations
Advisory Board and Contents	603
An ATM D-compartmentalization in DNA damage response	492
The postdoctoral blueprint part one: creating a niche	365
Translation is an emerging constraint on protein homeostasis in ageing	330
Modulating cell-free DNA biology as the next frontier in liquid biopsies	271
Understanding human embryogenesis by building programmable stem cell-based models	260
Centrosomes and cancer: balancing tumor-promoting and inhibitory roles	218
Unlocking Latin America´s scientific potential: challenges and opportunities in a globalized world	198
HELLS: the transcriptional sentinel	185
Plasticity of cancer invasion and energy metabolism	180
(Alternative) transcription start sites as regulators of RNA processing	174
The bidirectional relationship between metabolism and cell cycle control	174
The multifaceted mitochondrial OXA insertase	154
Lysosome: a critical hub for ferroptosis regulation	145
Whi3key old fashioned: a condensate cocktail for cell fate decisions	140
H3K9 trimethylation homeostasis: mechanisms, crosstalk, and cancer relevance	138
Optical tweezers across scales in cell biology	130
Cytoplasmic mtDNA clearance suppresses inflammatory immune responses	128
Subscription and Copyright Information	127
Membrane curvature at the ER–PM contact sites	127
Olfaction: an emerging regulator of longevity and metabolism	126
Advisory Board and Contents	122
Subscription and Copyright Information	119
Bucket lists must be completed during cell death	117
What makes genes burst	117

Where protein structure and cell diversity meet	103
Opportunities and challenges for deep learning in cell dynamics research	102
Regulation of lipid droplet dynamics and lipid homeostasis by hydroxysteroid dehydrogenase proteins	95
Progress and limitations in engineering cellular adhesion for research and therapeutics	93
Lessons in longevity from blood stem cells under protein stress	93
POGK is a domesticated KRAB domain-containing transposable element with tumor suppressive functions in breast cancer	89
DDX47 untangles R-loops with only certain other helicases	86
Bioelectric regulation of intestinal stem cells	84
Multifaceted mitochondrial quality control in brown adipose tissue	84
tRNA modifications: insights into their role in human cancers	83
Optimality as a framework for understanding developmental robustness	83
Deciphering the significance of p53 mutant proteins	82
The promiscuous ribosomal P-stalk: a new functional portrait	80
Diverse routes to mitophagy governed by ubiquitylation and mitochondrial import	79
The emergence of the stem cell niche	78
Cultured meat: creative solutions for a cell biological problem	78
Visualizing intracellular target antigens in live cells	77
Sublethal engagement of apoptotic pathways in residual cancer	77
Advisory Board and Contents	75
Reimagining journal clubs for inclusive scientific training	73
Wnt signalling in cell division: from mechanisms to tissue engineering	72
Biomolecular condensates: hubs of Hippo-YAP/TAZ signaling in cancer	72
Mitochondrial transfer at the crossroads of cancer, stromal, and immune cells	71
Moonlighting translation factors: multifunctionality drives diverse gene regulation	70
Endoplasmic reticulum (ER) protein degradation by ER-associated degradation and ER-phagy	69
Self-inflicted DNA breaks in cell differentiation and cancer	69
Reprogramming transcription after DNA damage: recognition, response, repair, and restart	67
Built to last: lysosome remodeling and repair in health and disease	66
Fun in the sun: ribosomes defend against UV irradiation	64
Accessible high-speed image-activated cell sorting	64
Tumor–stromal metabolic crosstalk in pancreatic cancer	64
Young researchers series #3	63
Advisory Board and Contents	62
Young researchers series #3	62
Advisory Board and Contents	62
Advisory Board and Contents	61
Telomere dynamics as mediators of gut microbiota–host interactions	60
ERMCS Ca2+ transmission fuels cell division	60
Filopodia: integrating cellular functions with theoretical models	59
Unique architectural features of mammalian mitochondrial protein synthesis	59
Membrane remodeling and trafficking piloted by SARS-CoV-2	59
Advisory Board and Contents	55
Embryos burn fat in standby	54
Subscription and Copyright Information	54
Young researchers series #7	52
Revealing new biology from multiplexed, metal-isotope-tagged, single-cell readouts	51
Thermoporter: a new regulatory mechanism for mitochondrial calcium uniporter activity	51
Meiotic spindle pushed outward by inward organelle packing	50
Transcription-coupled repair of DNA–protein crosslinks	49
Subscription and Copyright Information	49

Intravital and high-content multiplex imaging of the immune system	47
Advisory Board and Contents	46
Lysosomal functions of progranulin and implications for treatment of frontotemporal dementia	46
Advisory Board and Contents	46
Targeting SHP1 and SHP2 to suppress tumors and enhance immunosurveillance	46
Oxidative DNA damage and repair at non-coding regulatory regions	45
Subscription and Copyright Information	44
Orientational cell adhesions (OCAs) for tissue morphogenesis	44
Cell cycle regulation by the ribotoxic stress response	44
Order from chaos: cellular asymmetries explained with modelling	43
Chaperone networks are shaped by cellular differentiation and identity	42
Increased O-GlcNAcylation connects metabolic to transcriptional reprogramming during pathophysiological cell activation	42
Disruption of lineage integrity as a precursor to breast tumor initiation	41
Young researchers series #6	41
ER: a critical hub for STING signaling regulation	41
The idiosyncrasies of oocytes	41
Expanding roles of N-glycosylation in the endoplasmic reticulum	41
Phase separation on microtubules: from droplet formation to cellular function?	41
Versatility of gasdermin D beyond pyroptosis	40
Bloodhounds chasing the origin of blood cells	40
Cellular mechanics during division of a genomically minimal cell	40
Patterns in the tapestry of chromatin-bound RB	40
Sugar symphony: glycosylation in cancer metabolism and stemness	39
Lysosomal enzyme trafficking: from molecular mechanisms to human diseases	39
Mechanical regulation of cell-cycle progression and division	39
Subscription and Copyright Information	38
Regulation of gene expression by glycolytic and gluconeogenic enzymes	38
Subscription and Copyright Information	37
Death by ribosome	37
Spermidine – an old molecule with a new age-defying immune function	36
The neuronal-like behaviour of macrophages	36
Immune surveillance of senescence: potential application to age-related diseases	36
Subscription and Copyright Information	35
Creating inclusive environments in cell biology by casual mentoring	35
Advisory Board and Contents	35
Extracellular vesicle-mediated crosstalk in tumor microenvironment dominates tumor fate	34
Subscription and Copyright Information	34
New job for an old tool: PI3Kβ phosphorylates OGT to regulate acetyl-CoA in glioblastoma	34
Advisory Board and Contents	34
The adipocyte supersystem of insulin and cAMP signaling	34
Young researchers series #2	33
Changing the culture for the future: time to take brain drain in academics seriously	33
The peroxisome: an up-and-coming organelle in immunometabolism	33
The many faces of H3.3 in regulating chromatin in embryonic stem cells and beyond	32
CS proteins and ubiquitination: orchestrating DNA repair with transcription and cell division	32
Muscle is a stage, and cells and factors are merely players	32
The epigenetic landscape of mesenchymal stem cell and extracellular vesicle therapy	31
Targeting mitochondrial dynamics against cancer	31
Quality control of mitochondrial nucleoids	31
Stress-induced cell depolarization through the MAP kinase–Cdc42 axis	30
ER remodeling via lipid metabolism	30
The ubiquitin–proteasome system links NADPH metabolism to ferroptosis	29
Calcium homeostasis and cancer: insights from endoplasmic reticulum-centered organelle communications	29
The Cys/N-degron pathway in the ubiquitin–proteasome system and autophagy	29
Molecular mechanisms of nucleolar DNA damage checkpoint response	28
Chromatin-interacting RNA-binding proteins regulate transcription	28
Advisory Board and Contents	28
Subscription and Copyright Information	28
Advisory Board and Contents	27
Metabolic regulation of mRNA splicing	27
Advisory Board and Contents	27
Subscription and Copyright Information	27
Phase separation of p62: roles and regulations in autophagy	26
Emerging roles of intratumor microbiota in cancer metastasis	26
3′UTR heterogeneity and cancer progression	26
Regulated circRNA nuclear export in neuronal differentiation	26
Tumor-initiating cells establish a niche to overcome isolation stress	26
The heterogeneity of cellular senescence: insights at the single-cell level	26
Glucose metabolism of TAMs in tumor chemoresistance and metastasis	25
Subscription and Copyright Information	25
The Warburg effect: a signature of mitochondrial overload	25
ATRX loss induces lineage plasticity and squamous-like phenotype to promote colorectal cancer metastasis	24
Fracture in living tissues	24
Novel imaging methods and force probes for molecular mechanobiology of cytoskeleton and adhesion	24
Regulation of leukemogenesis via redox metabolism	24
Technological and computational advances driving high-throughput oncology	24
Decoding human cardiovascular development and disease through single-cell transcriptomic and epigenomic profiling	24
Time matters: the dynamics of plasma membrane repair	24
Subscription and Copyright Information	23
Advisory Board and Contents	23

Hard to handle: how lipid saturation affects the nuclear envelope	23
Subscription and Copyright Information	23
RNA G-quadruplexes and stress: emerging mechanisms and functions	22
Multifaceted collagen-DDR1 signaling in cancer	22
Extracellular vesicles from the dead: the final message	22
A stable start: cotranslational Nt-acetylation promotes proteome stability across kingdoms	22
TFEB links the cGAS-STING pathway to lysosome biogenesis	22
How pervasive are post-translational and -transcriptional modifications?	21
DNA single-strand break repair and human genetic disease	21
The autophagy–NAD axis in longevity and disease	21
Fumarate hydratase as a metabolic regulator of immunity	21
The two sides of creatine in cancer	21
Clonal hematopoiesis and inflammation – the perpetual cycle	20
Glucagon-producing α-cell transcriptional identity and reprogramming towards insulin production	20
Mechanism-aware and multimodal AI: beyond model-agnostic interpretation	20
Subscription and Copyright Information	19
Hypoxia-specific transcriptional condensates drive metastasis	19
Ferroptosis: mechanisms and implications for cancer development and therapy response	19
Celebrating 35 years of Trends in Cell Biology and introducing our special issue on ribosomal dynamics and cellular homeostasis	19
Neutral lipid quality control gates ferroptotic cell death	19
Advisory Board and Contents	19
The role of the immune tumor microenvironment in shaping metastatic dissemination, dormancy, and outgrowth	19
Ferroptosis as an approach to leverage cancer metabolism	19
Advancing cell biology with nanoscale fluorescence imaging: essential practical considerations	19
Subscription and Copyright Information	19
Implementing standardized diversity, equity, and inclusion approaches within scientific communities	18
The initiation of mammalian embryonic transcription: to begin at the beginning	18
Mitochondrial substrate oxidation regulates distinct cell differentiation outcomes	18
Extracellular matrix remodeling facilitates obesity-associated cancer progression	18
Mechanisms of cellular mRNA transcript homeostasis	17
Degradation of nuclear components via different autophagy pathways	17
Reflected stemness as a potential driver of the tumour microenvironment	17
Multiplicity of stem cell memories of inflammation and tissue repair in epithelia	17
The enigmatic roles of epithelial gasdermin B: Recent discoveries and controversies	17
Where you start could determine where you end up	16
Coordinated in confined migration: crosstalk between the nucleus and ion channel-mediated mechanosensation	16
The role of RAS oncogenes in controlling epithelial mechanics	16
A novel superfamily of bridge-like lipid transfer proteins	16
Subscription and Copyright Information	16
Spotlighting adult stem cells: advances, pitfalls, and challenges	16
Inter-membrane control of junctional InsP3 receptors by PIP2	16
Time as a danger signal promoting G1 arrest after mitosis	16
Experimental evolution for cell biology	15
Newly identified cell types crucial for gut commensal tolerance	15
Mechanobiology of organelles: illuminating their roles in mechanosensing and mechanotransduction	15
MDM4 exon skipping upon dysfunctional ribosome assembly	15
Organelle-specific signaling of cGAS–STING	15
CDK11, a splicing-associated kinase regulating gene expression	15
Cholesterol metabolism regulates macrophage function and inflammation-related diseases	14
PYK2, a hub of signaling networks in breast cancer progression	14
Cullin–RING receptors in rare disease biology	14
miRNA dosage control in development and human disease	14
Roles of YAP/TAZ in ferroptosis	14
3D genome folding in epigenetic regulation and cellular memory	13
Tau liquid–liquid phase separation in neurodegenerative diseases	13
NADH reductive stress drives metabolic reprogramming	13
Advisory Board and Contents	13
Cellular plasticity in reprogramming, rejuvenation and tumorigenesis: a pioneer TF perspective	13
The cell biology of APOE in the brain	13
Triple threat: neutrophil ER stress, NETosis, airway inflammation escalation	13
Lysosomal microautophagy: an emerging dimension in mammalian autophagy	13
Vimentin at the core of wound healing	13
The culture and application of circulating tumor cell-derived organoids	13
Emerging roles of olfactory receptors in glucose metabolism	12
Regulatory landscape of enhancer-mediated transcriptional activation	12
Arming a killer: mitochondrial regulation of CD8+ T cell cytotoxicity	12
Plasma membrane damage is a new trigger of cellular senescence	12
Central role of the ER proteostasis network in healthy aging	12
Is clathrin a membrane fission protein?	12
Advisory Board and Contents	12
Autophagosomal components recycling on autolysosomes	11
Experimental tools and emerging principles of organellar mechanotransduction	11
Subscription and Copyright Information	11
Integrating mechanical signals into cellular identity	11
Metabolism and HSC fate: what NADPH is made for	11
Subscription and Copyright Information	11
Is euchromatin really open in the cell?	11
Advisory Board and Contents	11
The ins-and-outs of exosome biogenesis, secretion, and internalization	11
Metabolism and mRNA translation: a nexus of cancer plasticity	11
Phenotypic plasticity during metastatic colonization	11
Navigating AKT-ivity across cellular compartments	10
How it feels in a cell	10
Advisory Board and Contents	10
Role of lipids in interorganelle communication	10
Gasdermins gone wild: new roles for GSDMs in regulating cellular homeostasis	10
Nutrient availability as an arbiter of cell size	10
The multifaceted role of kidney tubule mitochondrial dysfunction in kidney disease development	10
Towards solving the mystery of peroxisomal matrix protein import	10
Transsulfuration, minor player or crucial for cysteine homeostasis in cancer	10
Targeting of biomolecular condensates to the autophagy pathway	9
Advisory Board and Contents	9
Disulfidptosis: disulfide stress–induced cell death	9
Lysosomal control of the cGAS-STING signaling	9
Mitochondria in cancer stem cells: Achilles heel or hard armor	9