Trends in Cell Biology

Article	Citations
Advisory Board and Contents	414
(Alternative) transcription start sites as regulators of RNA processing	282
Unlocking Latin America´s scientific potential: challenges and opportunities in a globalized world	264
HELLS: the transcriptional sentinel	236
An ATM D-compartmentalization in DNA damage response	188
DNA-PKcs kinase activity orchestrates both end-processing and end-ligation	181
Modulating cell-free DNA biology as the next frontier in liquid biopsies	176
The postdoctoral blueprint part one: creating a niche	149
Centrosomes and cancer: balancing tumor-promoting and inhibitory roles	138
Plasticity of cancer invasion and energy metabolism	135
The bidirectional relationship between metabolism and cell cycle control	134
Subscription and Copyright Information	132
Translation is an emerging constraint on protein homeostasis in ageing	132
Subscription and Copyright Information	128
Advisory Board and Contents	125
Cytoplasmic mtDNA clearance suppresses inflammatory immune responses	119
A glitch in the matrix: organ-specific matrisomes in metastatic niches	112
Bucket lists must be completed during cell death	111
Olfaction: an emerging regulator of longevity and metabolism	110
Regulation of lipid droplet dynamics and lipid homeostasis by hydroxysteroid dehydrogenase proteins	104
Where protein structure and cell diversity meet	100
Primary ciliary signaling: links with the cell cycle	95
Optical tweezers across scales in cell biology	92
The multifaceted mitochondrial OXA insertase	92
Opportunities and challenges for deep learning in cell dynamics research	90

Subscription and Copyright Information	86
Multifaceted mitochondrial quality control in brown adipose tissue	86
tRNA modifications: insights into their role in human cancers	85
The emergence of the stem cell niche	85
Interphase microtubules in nuclear organization and genome maintenance	83
DDX47 untangles R-loops with only certain other helicases	81
POGK is a domesticated KRAB domain-containing transposable element with tumor suppressive functions in breast cancer	79
Bioelectric regulation of intestinal stem cells	75
Progress and limitations in engineering cellular adhesion for research and therapeutics	75
Sublethal engagement of apoptotic pathways in residual cancer	74
Cultured meat: creative solutions for a cell biological problem	71
Diverse routes to mitophagy governed by ubiquitylation and mitochondrial import	70
Lessons in longevity from blood stem cells under protein stress	70
Deciphering the significance of p53 mutant proteins	69
Advisory Board and Contents	68
Subscription and Copyright Information	68
Self-inflicted DNA breaks in cell differentiation and cancer	67
Moonlighting translation factors: multifunctionality drives diverse gene regulation	66
Visualizing intracellular target antigens in live cells	64
Reimagining journal clubs for inclusive scientific training	64
Tumor–stromal metabolic crosstalk in pancreatic cancer	62
Wnt signalling in cell division: from mechanisms to tissue engineering	61
Reprogramming transcription after DNA damage: recognition, response, repair, and restart	61
Accessible high-speed image-activated cell sorting	60
Shared genetic and epigenetic changes link aging and cancer	59
Biomolecular condensates: hubs of Hippo-YAP/TAZ signaling in cancer	59
Built to last: lysosome remodeling and repair in health and disease	58
Endoplasmic reticulum (ER) protein degradation by ER-associated degradation and ER-phagy	58
Subscription and Copyright Information	57
Young researchers series #7	56
Transcription-coupled repair of DNA–protein crosslinks	56
Young researchers series #3	56
Young researchers series #3	56
Advisory Board and Contents	56
Differentiation of the tumor microenvironment: are CAFs the Organizer?	54
Meiotic spindle pushed outward by inward organelle packing	54
Fun in the sun: ribosomes defend against UV irradiation	54
Filopodia: integrating cellular functions with theoretical models	54
Advisory Board and Contents	53
Embryos burn fat in standby	52
Principles of membrane remodeling by dynamic ESCRT-III polymers	50
Advisory Board and Contents	50
Membrane remodeling and trafficking piloted by SARS-CoV-2	49
Thermoporter: a new regulatory mechanism for mitochondrial calcium uniporter activity	48
ERMCS Ca2+ transmission fuels cell division	48
Revealing new biology from multiplexed, metal-isotope-tagged, single-cell readouts	48
Unique architectural features of mammalian mitochondrial protein synthesis	48
Intravital and high-content multiplex imaging of the immune system	47
Telomere dynamics as mediators of gut microbiota–host interactions	45
Targeting SHP1 and SHP2 to suppress tumors and enhance immunosurveillance	45

Lysosomal functions of progranulin and implications for treatment of frontotemporal dementia	44
Mechanical communication in fibrosis progression	44
Putative homeostatic role of cancer driver mutations	43
Advisory Board and Contents	42
Advisory Board and Contents	41
Subscription and Copyright Information	41
Order from chaos: cellular asymmetries explained with modelling	40
Orientational cell adhesions (OCAs) for tissue morphogenesis	40
The idiosyncrasies of oocytes	39
Oxidative DNA damage and repair at non-coding regulatory regions	39
Modulation of membrane–cytoskeleton interactions: ezrin as key player	39
Cell cycle regulation by the ribotoxic stress response	39
Increased O-GlcNAcylation connects metabolic to transcriptional reprogramming during pathophysiological cell activation	38
Phase separation on microtubules: from droplet formation to cellular function?	38
Chaperone networks are shaped by cellular differentiation and identity	38
ER: a critical hub for STING signaling regulation	38
Versatility of gasdermin D beyond pyroptosis	37
Cellular mechanics during division of a genomically minimal cell	37
Young researchers series #6	37
Bloodhounds chasing the origin of blood cells	36
Sugar symphony: glycosylation in cancer metabolism and stemness	36
Disruption of lineage integrity as a precursor to breast tumor initiation	36
Patterns in the tapestry of chromatin-bound RB	35
The amoeboid state as part of the epithelial-to-mesenchymal transition programme	35
Mechanical regulation of cell-cycle progression and division	35
Advisory Board and Contents	34
Lysosomal enzyme trafficking: from molecular mechanisms to human diseases	34
Subscription and Copyright Information	34
Regulation of gene expression by glycolytic and gluconeogenic enzymes	34
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Hierarchical folding of the catalytic core during mitochondrial ribosome biogenesis	33
Advisory Board and Contents	33
Subscription and Copyright Information	33
Subscription and Copyright Information	33
Creating inclusive environments in cell biology by casual mentoring	32
New job for an old tool: PI3Kβ phosphorylates OGT to regulate acetyl-CoA in glioblastoma	32
Spatiotemporal dynamic regulation of membraneless organelles by chaperone networks	31
The adipocyte supersystem of insulin and cAMP signaling	31
Extracellular vesicle-mediated crosstalk in tumor microenvironment dominates tumor fate	31
Hidden protein functions and what they may teach us	30
Spermidine – an old molecule with a new age-defying immune function	30
The neuronal-like behaviour of macrophages	30
Death by ribosome	29
Immune surveillance of senescence: potential application to age-related diseases	29
Stress relief: emerging methods to mitigate dissociation-induced artefacts	29
Redefining actin dynamics of the pointed-end complex in striated muscle	28
The peroxisome: an up-and-coming organelle in immunometabolism	28
Stress-induced cell depolarization through the MAP kinase–Cdc42 axis	28
Advisory Board and Contents	28
Young researchers series #2	28
The many faces of H3.3 in regulating chromatin in embryonic stem cells and beyond	27
ER remodeling via lipid metabolism	27
The epigenetic landscape of mesenchymal stem cell and extracellular vesicle therapy	27
Changing the culture for the future: time to take brain drain in academics seriously	26
The Cys/N-degron pathway in the ubiquitin–proteasome system and autophagy	26
Muscle is a stage, and cells and factors are merely players	26
The ubiquitin–proteasome system links NADPH metabolism to ferroptosis	26
Calcium homeostasis and cancer: insights from endoplasmic reticulum-centered organelle communications	25
Quality control of mitochondrial nucleoids	25
CS proteins and ubiquitination: orchestrating DNA repair with transcription and cell division	25
Tumor-initiating cells establish a niche to overcome isolation stress	24
Advisory Board and Contents	24
Regulated circRNA nuclear export in neuronal differentiation	24
Advisory Board and Contents	24
The heterogeneity of cellular senescence: insights at the single-cell level	23
Molecular mechanisms of nucleolar DNA damage checkpoint response	23
Glucose metabolism of TAMs in tumor chemoresistance and metastasis	23
Phase separation of p62: roles and regulations in autophagy	23
Metabolic regulation of mRNA splicing	23
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Chromatin-interacting RNA-binding proteins regulate transcription	22
Hard to handle: how lipid saturation affects the nuclear envelope	22
The Warburg effect: a signature of mitochondrial overload	22
Emerging roles of intratumor microbiota in cancer metastasis	22
3′UTR heterogeneity and cancer progression	22
How should we define mammary stem cells?	22
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Advisory Board and Contents	22
The state of F-BAR domains as membrane-bound oligomeric platforms	22
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Chromatin dynamics in human brain development and disease	21
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Decoding human cardiovascular development and disease through single-cell transcriptomic and epigenomic profiling	20
TFEB links the cGAS-STING pathway to lysosome biogenesis	20
A stable start: cotranslational Nt-acetylation promotes proteome stability across kingdoms	20
The two sides of creatine in cancer	20
Fracture in living tissues	20
Time matters: the dynamics of plasma membrane repair	20
Extracellular vesicles from the dead: the final message	20
The autophagy–NAD axis in longevity and disease	19
Technological and computational advances driving high-throughput oncology	19
Regulation of leukemogenesis via redox metabolism	19
DNA single-strand break repair and human genetic disease	19
Multifaceted collagen-DDR1 signaling in cancer	19
Mitotic disassembly and reassembly of nuclear pore complexes	19
Novel imaging methods and force probes for molecular mechanobiology of cytoskeleton and adhesion	19
RNA G-quadruplexes and stress: emerging mechanisms and functions	18
Bivalent recognition of histone marks by BARD1	18
Fumarate hydratase as a metabolic regulator of immunity	18
Celebrating 35 years of Trends in Cell Biology and introducing our special issue on ribosomal dynamics and cellular homeostasis	18
Subscription and Copyright Information	18
ATRX loss induces lineage plasticity and squamous-like phenotype to promote colorectal cancer metastasis	18
Mechanism-aware and multimodal AI: beyond model-agnostic interpretation	18
Nucleus segmentation: towards automated solutions	17
DNA replication: the recombination connection	17
Clonal hematopoiesis and inflammation – the perpetual cycle	17
The role of the immune tumor microenvironment in shaping metastatic dissemination, dormancy, and outgrowth	17
Glucagon-producing α-cell transcriptional identity and reprogramming towards insulin production	17
Cyclin E in normal physiology and disease states	16
The enigmatic roles of epithelial gasdermin B: Recent discoveries and controversies	16
How pervasive are post-translational and -transcriptional modifications?	16
Primordial super-enhancers: heat shock-induced chromatin organization in yeast	16
Hypoxia-specific transcriptional condensates drive metastasis	16
Ferroptosis: mechanisms and implications for cancer development and therapy response	16
Advancing cell biology with nanoscale fluorescence imaging: essential practical considerations	16
Advisory Board and Contents	16
Mitochondrial substrate oxidation regulates distinct cell differentiation outcomes	15
Unfolding by Cdc48/p97: different strokes for different folks	15
Reflected stemness as a potential driver of the tumour microenvironment	15
Multiplicity of stem cell memories of inflammation and tissue repair in epithelia	15
Implementing standardized diversity, equity, and inclusion approaches within scientific communities	15
The role of RAS oncogenes in controlling epithelial mechanics	14
Spotlighting adult stem cells: advances, pitfalls, and challenges	14
Extracellular matrix remodeling facilitates obesity-associated cancer progression	14
Mechanisms of cellular mRNA transcript homeostasis	13
Inter-membrane control of junctional InsP3 receptors by PIP2	13
A novel superfamily of bridge-like lipid transfer proteins	13
Degradation of nuclear components via different autophagy pathways	13
The culture and application of circulating tumor cell-derived organoids	13
The initiation of mammalian embryonic transcription: to begin at the beginning	13
Subscription and Copyright Information	13
Coordinated in confined migration: crosstalk between the nucleus and ion channel-mediated mechanosensation	12
CDK11, a splicing-associated kinase regulating gene expression	12
Experimental evolution for cell biology	12
MDM4 exon skipping upon dysfunctional ribosome assembly	12
3D genome folding in epigenetic regulation and cellular memory	12
Roles of YAP/TAZ in ferroptosis	12
Time as a danger signal promoting G1 arrest after mitosis	12
Lysosomal microautophagy: an emerging dimension in mammalian autophagy	12
PYK2, a hub of signaling networks in breast cancer progression	12
Cellular plasticity in reprogramming, rejuvenation and tumorigenesis: a pioneer TF perspective	11
Phase separation in genome organization across evolution	11
Mechanobiology of organelles: illuminating their roles in mechanosensing and mechanotransduction	11
Tau liquid–liquid phase separation in neurodegenerative diseases	11
Vimentin at the core of wound healing	11
Newly identified cell types crucial for gut commensal tolerance	11
miRNA dosage control in development and human disease	11
The cell biology of APOE in the brain	11
Advisory Board and Contents	11
Is clathrin a membrane fission protein?	10
Plasma membrane damage is a new trigger of cellular senescence	10
Central role of the ER proteostasis network in healthy aging	10
The ins-and-outs of exosome biogenesis, secretion, and internalization	10
Metabolic and epigenetic regulation of endoderm differentiation	10
Regulatory landscape of enhancer-mediated transcriptional activation	10
Cell cycle on the crossroad of tumorigenesis and cancer therapy	10
Arming a killer: mitochondrial regulation of CD8+ T cell cytotoxicity	10
Triple threat: neutrophil ER stress, NETosis, airway inflammation escalation	10
Experimental tools and emerging principles of organellar mechanotransduction	10
Emerging roles of olfactory receptors in glucose metabolism	10
REV7: Jack of many trades	10
Metabolism and mRNA translation: a nexus of cancer plasticity	9
Autophagosomal components recycling on autolysosomes	9
E2 enzymes in genome stability: pulling the strings behind the scenes	9
Phenotypic plasticity during metastatic colonization	9
Towards solving the mystery of peroxisomal matrix protein import	9
Integrating mechanical signals into cellular identity	9
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Metabolism and HSC fate: what NADPH is made for	9
How it feels in a cell	9
Human embryonic development: from peri-implantation to gastrulation	8
Is euchromatin really open in the cell?	8
The multifaceted role of kidney tubule mitochondrial dysfunction in kidney disease development	8
Nutrient availability as an arbiter of cell size	8