Trends in Cell Biology

Article	Citations
Advisory Board and Contents	482
Translation is an emerging constraint on protein homeostasis in ageing	344
Unlocking Latin America´s scientific potential: challenges and opportunities in a globalized world	290
Understanding human embryogenesis by building programmable stem cell-based models	279
Centrosomes and cancer: balancing tumor-promoting and inhibitory roles	218
DNA-PKcs kinase activity orchestrates both end-processing and end-ligation	213
An ATM D-compartmentalization in DNA damage response	203
The postdoctoral blueprint part one: creating a niche	167
Modulating cell-free DNA biology as the next frontier in liquid biopsies	156
HELLS: the transcriptional sentinel	152
(Alternative) transcription start sites as regulators of RNA processing	150
Plasticity of cancer invasion and energy metabolism	150
The bidirectional relationship between metabolism and cell cycle control	146
What makes genes burst	142
Optical tweezers across scales in cell biology	141
Olfaction: an emerging regulator of longevity and metabolism	135
Where protein structure and cell diversity meet	130
Advisory Board and Contents	125
Subscription and Copyright Information	117
Subscription and Copyright Information	105
Primary ciliary signaling: links with the cell cycle	103
Opportunities and challenges for deep learning in cell dynamics research	102
A glitch in the matrix: organ-specific matrisomes in metastatic niches	101
Regulation of lipid droplet dynamics and lipid homeostasis by hydroxysteroid dehydrogenase proteins	101
Bucket lists must be completed during cell death	101

Cytoplasmic mtDNA clearance suppresses inflammatory immune responses	98
The multifaceted mitochondrial OXA insertase	97
Lessons in longevity from blood stem cells under protein stress	95
POGK is a domesticated KRAB domain-containing transposable element with tumor suppressive functions in breast cancer	91
The promiscuous ribosomal P-stalk: a new functional portrait	83
Optimality as a framework for understanding developmental robustness	82
DDX47 untangles R-loops with only certain other helicases	82
Subscription and Copyright Information	81
Bioelectric regulation of intestinal stem cells	79
Sublethal engagement of apoptotic pathways in residual cancer	75
Multifaceted mitochondrial quality control in brown adipose tissue	74
tRNA modifications: insights into their role in human cancers	74
Diverse routes to mitophagy governed by ubiquitylation and mitochondrial import	72
Progress and limitations in engineering cellular adhesion for research and therapeutics	72
Cultured meat: creative solutions for a cell biological problem	72
The emergence of the stem cell niche	71
Deciphering the significance of p53 mutant proteins	70
Visualizing intracellular target antigens in live cells	70
Reimagining journal clubs for inclusive scientific training	69
Advisory Board and Contents	69
Subscription and Copyright Information	68
Self-inflicted DNA breaks in cell differentiation and cancer	68
Reprogramming transcription after DNA damage: recognition, response, repair, and restart	67
Moonlighting translation factors: multifunctionality drives diverse gene regulation	67
Accessible high-speed image-activated cell sorting	66
Wnt signalling in cell division: from mechanisms to tissue engineering	64
Endoplasmic reticulum (ER) protein degradation by ER-associated degradation and ER-phagy	63
Biomolecular condensates: hubs of Hippo-YAP/TAZ signaling in cancer	62
Built to last: lysosome remodeling and repair in health and disease	62
Shared genetic and epigenetic changes link aging and cancer	62
Tumor–stromal metabolic crosstalk in pancreatic cancer	61
Fun in the sun: ribosomes defend against UV irradiation	60
Transcription-coupled repair of DNA–protein crosslinks	59
Telomere dynamics as mediators of gut microbiota–host interactions	59
Advisory Board and Contents	59
Membrane remodeling and trafficking piloted by SARS-CoV-2	58
Unique architectural features of mammalian mitochondrial protein synthesis	56
Young researchers series #3	55
Advisory Board and Contents	55
ERMCS Ca2+ transmission fuels cell division	55
Lysosomal functions of progranulin and implications for treatment of frontotemporal dementia	54
Mechanical communication in fibrosis progression	54
Targeting SHP1 and SHP2 to suppress tumors and enhance immunosurveillance	54
Advisory Board and Contents	53
Meiotic spindle pushed outward by inward organelle packing	51
Embryos burn fat in standby	51
Filopodia: integrating cellular functions with theoretical models	50
Young researchers series #7	49
Subscription and Copyright Information	47
Young researchers series #3	47

Revealing new biology from multiplexed, metal-isotope-tagged, single-cell readouts	47
Thermoporter: a new regulatory mechanism for mitochondrial calcium uniporter activity	46
Differentiation of the tumor microenvironment: are CAFs the Organizer?	46
Advisory Board and Contents	45
Intravital and high-content multiplex imaging of the immune system	45
The idiosyncrasies of oocytes	45
Advisory Board and Contents	44
ER: a critical hub for STING signaling regulation	42
Chaperone networks are shaped by cellular differentiation and identity	42
Cell cycle regulation by the ribotoxic stress response	41
Modulation of membrane–cytoskeleton interactions: ezrin as key player	41
Increased O-GlcNAcylation connects metabolic to transcriptional reprogramming during pathophysiological cell activation	40
Subscription and Copyright Information	40
Orientational cell adhesions (OCAs) for tissue morphogenesis	40
Phase separation on microtubules: from droplet formation to cellular function?	40
Putative homeostatic role of cancer driver mutations	40
Oxidative DNA damage and repair at non-coding regulatory regions	40
Order from chaos: cellular asymmetries explained with modelling	40
Bloodhounds chasing the origin of blood cells	39
Versatility of gasdermin D beyond pyroptosis	38
Sugar symphony: glycosylation in cancer metabolism and stemness	38
Patterns in the tapestry of chromatin-bound RB	37
Cellular mechanics during division of a genomically minimal cell	37
Lysosomal enzyme trafficking: from molecular mechanisms to human diseases	37
Disruption of lineage integrity as a precursor to breast tumor initiation	37
Young researchers series #6	36
Regulation of gene expression by glycolytic and gluconeogenic enzymes	36
The amoeboid state as part of the epithelial-to-mesenchymal transition programme	36
Mechanical regulation of cell-cycle progression and division	36
Subscription and Copyright Information	36
Subscription and Copyright Information	35
New job for an old tool: PI3Kβ phosphorylates OGT to regulate acetyl-CoA in glioblastoma	34
Death by ribosome	33
The neuronal-like behaviour of macrophages	33
Extracellular vesicle-mediated crosstalk in tumor microenvironment dominates tumor fate	33
The peroxisome: an up-and-coming organelle in immunometabolism	33
Immune surveillance of senescence: potential application to age-related diseases	32
Stress relief: emerging methods to mitigate dissociation-induced artefacts	32
Advisory Board and Contents	32
Subscription and Copyright Information	32
Hidden protein functions and what they may teach us	31
Subscription and Copyright Information	31
Creating inclusive environments in cell biology by casual mentoring	31
Advisory Board and Contents	31
Spatiotemporal dynamic regulation of membraneless organelles by chaperone networks	30
The adipocyte supersystem of insulin and cAMP signaling	30
Hierarchical folding of the catalytic core during mitochondrial ribosome biogenesis	30
The epigenetic landscape of mesenchymal stem cell and extracellular vesicle therapy	29
Spermidine – an old molecule with a new age-defying immune function	29
Quality control of mitochondrial nucleoids	29
The many faces of H3.3 in regulating chromatin in embryonic stem cells and beyond	29
Changing the culture for the future: time to take brain drain in academics seriously	28
Young researchers series #2	28
Stress-induced cell depolarization through the MAP kinase–Cdc42 axis	28
ER remodeling via lipid metabolism	27
CS proteins and ubiquitination: orchestrating DNA repair with transcription and cell division	27
Muscle is a stage, and cells and factors are merely players	27
Advisory Board and Contents	27
The Cys/N-degron pathway in the ubiquitin–proteasome system and autophagy	27
Calcium homeostasis and cancer: insights from endoplasmic reticulum-centered organelle communications	27
The ubiquitin–proteasome system links NADPH metabolism to ferroptosis	26
Subscription and Copyright Information	26
Regulated circRNA nuclear export in neuronal differentiation	26
Tumor-initiating cells establish a niche to overcome isolation stress	25
Glucose metabolism of TAMs in tumor chemoresistance and metastasis	25
Advisory Board and Contents	25
Chromatin-interacting RNA-binding proteins regulate transcription	24
Emerging roles of intratumor microbiota in cancer metastasis	24
Phase separation of p62: roles and regulations in autophagy	24
Advisory Board and Contents	24
Advisory Board and Contents	24
The Warburg effect: a signature of mitochondrial overload	24
3′UTR heterogeneity and cancer progression	23
Molecular mechanisms of nucleolar DNA damage checkpoint response	23
The heterogeneity of cellular senescence: insights at the single-cell level	23
Metabolic regulation of mRNA splicing	23
ATRX loss induces lineage plasticity and squamous-like phenotype to promote colorectal cancer metastasis	22
Fracture in living tissues	22
Subscription and Copyright Information	22
Extracellular vesicles from the dead: the final message	22

Decoding human cardiovascular development and disease through single-cell transcriptomic and epigenomic profiling	21
Fumarate hydratase as a metabolic regulator of immunity	21
A stable start: cotranslational Nt-acetylation promotes proteome stability across kingdoms	21
The autophagy–NAD axis in longevity and disease	21
Multifaceted collagen-DDR1 signaling in cancer	21
Subscription and Copyright Information	20
Advisory Board and Contents	20
Subscription and Copyright Information	20
Chromatin dynamics in human brain development and disease	19
Novel imaging methods and force probes for molecular mechanobiology of cytoskeleton and adhesion	19
Regulation of leukemogenesis via redox metabolism	19
Hard to handle: how lipid saturation affects the nuclear envelope	19
Technological and computational advances driving high-throughput oncology	19
Time matters: the dynamics of plasma membrane repair	19
The role of the immune tumor microenvironment in shaping metastatic dissemination, dormancy, and outgrowth	18
Mitotic disassembly and reassembly of nuclear pore complexes	18
DNA single-strand break repair and human genetic disease	18
TFEB links the cGAS-STING pathway to lysosome biogenesis	18
RNA G-quadruplexes and stress: emerging mechanisms and functions	18
The two sides of creatine in cancer	18
Celebrating 35 years of Trends in Cell Biology and introducing our special issue on ribosomal dynamics and cellular homeostasis	17
Subscription and Copyright Information	17
Advancing cell biology with nanoscale fluorescence imaging: essential practical considerations	17
Glucagon-producing α-cell transcriptional identity and reprogramming towards insulin production	17
Hypoxia-specific transcriptional condensates drive metastasis	16
Nucleus segmentation: towards automated solutions	16
Mechanism-aware and multimodal AI: beyond model-agnostic interpretation	16
Clonal hematopoiesis and inflammation – the perpetual cycle	16
Ferroptosis: mechanisms and implications for cancer development and therapy response	16
Mitochondrial substrate oxidation regulates distinct cell differentiation outcomes	16
DNA replication: the recombination connection	16
How pervasive are post-translational and -transcriptional modifications?	16
Implementing standardized diversity, equity, and inclusion approaches within scientific communities	15
Unfolding by Cdc48/p97: different strokes for different folks	15
The initiation of mammalian embryonic transcription: to begin at the beginning	15
Advisory Board and Contents	15
Spotlighting adult stem cells: advances, pitfalls, and challenges	15
A novel superfamily of bridge-like lipid transfer proteins	15
Multiplicity of stem cell memories of inflammation and tissue repair in epithelia	15
The role of RAS oncogenes in controlling epithelial mechanics	15
Reflected stemness as a potential driver of the tumour microenvironment	15
Degradation of nuclear components via different autophagy pathways	14
Mechanisms of cellular mRNA transcript homeostasis	14
The enigmatic roles of epithelial gasdermin B: Recent discoveries and controversies	14
Organelle-specific signaling of cGAS–STING	13
Cellular plasticity in reprogramming, rejuvenation and tumorigenesis: a pioneer TF perspective	13
Extracellular matrix remodeling facilitates obesity-associated cancer progression	13
PYK2, a hub of signaling networks in breast cancer progression	13
Newly identified cell types crucial for gut commensal tolerance	13
CDK11, a splicing-associated kinase regulating gene expression	13
3D genome folding in epigenetic regulation and cellular memory	13
Inter-membrane control of junctional InsP3 receptors by PIP2	13
MDM4 exon skipping upon dysfunctional ribosome assembly	12
Time as a danger signal promoting G1 arrest after mitosis	12
Mechanobiology of organelles: illuminating their roles in mechanosensing and mechanotransduction	12
Experimental evolution for cell biology	12
Coordinated in confined migration: crosstalk between the nucleus and ion channel-mediated mechanosensation	12
Subscription and Copyright Information	12
The culture and application of circulating tumor cell-derived organoids	12
NADH reductive stress drives metabolic reprogramming	12
Regulatory landscape of enhancer-mediated transcriptional activation	11
Is clathrin a membrane fission protein?	11
Vimentin at the core of wound healing	11
Triple threat: neutrophil ER stress, NETosis, airway inflammation escalation	11
Tau liquid–liquid phase separation in neurodegenerative diseases	11
miRNA dosage control in development and human disease	11
Roles of YAP/TAZ in ferroptosis	11
Advisory Board and Contents	11
The cell biology of APOE in the brain	11
Lysosomal microautophagy: an emerging dimension in mammalian autophagy	11
Metabolism and mRNA translation: a nexus of cancer plasticity	10
Arming a killer: mitochondrial regulation of CD8+ T cell cytotoxicity	10
The ins-and-outs of exosome biogenesis, secretion, and internalization	10
Navigating AKT-ivity across cellular compartments	10
Metabolic and epigenetic regulation of endoderm differentiation	10
Emerging roles of olfactory receptors in glucose metabolism	10
Central role of the ER proteostasis network in healthy aging	10
Subscription and Copyright Information	10
Experimental tools and emerging principles of organellar mechanotransduction	10
Plasma membrane damage is a new trigger of cellular senescence	10
Cell cycle on the crossroad of tumorigenesis and cancer therapy	10
Role of lipids in interorganelle communication	9
Human embryonic development: from peri-implantation to gastrulation	9
Gasdermins gone wild: new roles for GSDMs in regulating cellular homeostasis	9
Phenotypic plasticity during metastatic colonization	9
Towards solving the mystery of peroxisomal matrix protein import	9
Metabolism and HSC fate: what NADPH is made for	9
Integrating mechanical signals into cellular identity	9
Subscription and Copyright Information	9
How it feels in a cell	9
Autophagosomal components recycling on autolysosomes	9
Is euchromatin really open in the cell?	9
Advisory Board and Contents	8
Mitochondria in cancer stem cells: Achilles heel or hard armor	8
The yin and yang of nuclear envelope breakdown through the activity of phosphatase holoenzyme PP2A-B55SUR-6	8