OOIR: Observatory of International Research

Papers

(The H4-Index of Bioorganic & Medicinal Chemistry is 28. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)

Article	Citations
Synthesis and antiproliferative activity of (−)-cleistenolide, (6S)-cleistenolide and 4-substituted cleistenolide analogues	139
Current Japanese pharmaceutical chemistry	90
Targeting prolidase. A survey of the literature data to depict a structure-activity relationship frame and to address future studies for drug development	75
Innovative synthesis and purification method of fluorescent and bifunctional substrates for self-labelling protein tags	74
Development of delivery carriers for plasmid DNA by conjugation of a helical template to oligoarginine	51
Synthesis and medicinal chemistry of tetronamides: Promising agrochemicals and antitumoral compounds	47
Synthesis and biological evaluation of pyrazole-fused oleanolic acid derivatives as novel inhibitors of inflammatory and osteoclast differentiation	46
Graphical abstract TOC	43
Design, synthesis and validation of a new Crimped Head-Piece for DNA-Encoded libraries generation	41
Production and synthesis of a novel 191Pt-labeled platinum complex and evaluation of its biodistribution in healthy mice	40
Contents continued	40
A DNA-encoded library special issue	39
Crescent-shaped meta-substituted benzene derivatives as a new class of non-nucleoside ribonuclease A inhibitors	38
Editorial Board	37
Natural product-derived antifungals against Candida albicans: Chemical diversity and mechanisms of action	36
Targeting m6A binding protein YTHDFs for cancer therapy	35
Selective targeting of human TET1 by cyclic peptide inhibitors: Insights from biochemical profiling	34
Discovery of trisubstituted meta-carboranes as T cell activators by regulating CD28 cytoplasmic region and SH2 domains of Grb2 and PI3K interactions	33
Design, synthesis, biological activity and molecular docking studies of triazolopyridine derivatives as ASK1 inhibitors	32
Sustainable electrochemical C(sp3) − H oxygenation using water as the oxygen source	31
Decades old glitazones still find niche in drug discoveries as PPAR-γ agonists: medicinal chemistry perspective, structure-activity relationships and therapeutic implications	31
Exploring novel A2AAR antagonists: Design, synthesis, and evaluation of 2,6,9-trisubstituted purine derivatives as promising antifibrotic agents	31
Sulfadoxine derivatization through multicomponent reactions to obtain new antiplasmodial compounds	30
Discovery of novel 2,8-diazaspiro[4.5]decan-1-one derivatives as potent RIPK1 kinase inhibitors	30
Multiple approaches to repurposing drugs for neuroblastoma	29

RNA-templated chemical synthesis of proapoptotic L- and d-peptides	29
Design, synthesis and evaluation the bioactivities of novel 1,3-dimethyl-6-amino-1H-indazole derivatives as anticancer agents	28
Janus dendritic ionizable lipids with fine designed headgroup and tails to improve mRNA delivery efficiency	28
Research progress of STAT3-based dual inhibitors for cancer therapy	28
Design, synthesis and antibacterial evaluation of oxazolidinone derivatives containing N-methylglycyl or quaternary ammonium salts	28