Bioorganic & Medicinal Chemistry

Article	Citations
Synthesis and antiproliferative activity of (−)-cleistenolide, (6S)-cleistenolide and 4-substituted cleistenolide analogues	139
Current Japanese pharmaceutical chemistry	90
Targeting prolidase. A survey of the literature data to depict a structure-activity relationship frame and to address future studies for drug development	75
Innovative synthesis and purification method of fluorescent and bifunctional substrates for self-labelling protein tags	74
Development of delivery carriers for plasmid DNA by conjugation of a helical template to oligoarginine	51
Synthesis and medicinal chemistry of tetronamides: Promising agrochemicals and antitumoral compounds	47
Synthesis and biological evaluation of pyrazole-fused oleanolic acid derivatives as novel inhibitors of inflammatory and osteoclast differentiation	46
Graphical abstract TOC	43
Design, synthesis and validation of a new Crimped Head-Piece for DNA-Encoded libraries generation	41
Production and synthesis of a novel 191Pt-labeled platinum complex and evaluation of its biodistribution in healthy mice	40
Contents continued	40
A DNA-encoded library special issue	39
Crescent-shaped meta-substituted benzene derivatives as a new class of non-nucleoside ribonuclease A inhibitors	38
Editorial Board	37
Natural product-derived antifungals against Candida albicans: Chemical diversity and mechanisms of action	36
Targeting m6A binding protein YTHDFs for cancer therapy	35
Selective targeting of human TET1 by cyclic peptide inhibitors: Insights from biochemical profiling	34
Discovery of trisubstituted meta-carboranes as T cell activators by regulating CD28 cytoplasmic region and SH2 domains of Grb2 and PI3K interactions	33
Design, synthesis, biological activity and molecular docking studies of triazolopyridine derivatives as ASK1 inhibitors	32
Decades old glitazones still find niche in drug discoveries as PPAR-γ agonists: medicinal chemistry perspective, structure-activity relationships and therapeutic implications	31
Exploring novel A2AAR antagonists: Design, synthesis, and evaluation of 2,6,9-trisubstituted purine derivatives as promising antifibrotic agents	31
Sustainable electrochemical C(sp3) − H oxygenation using water as the oxygen source	31
Discovery of novel 2,8-diazaspiro[4.5]decan-1-one derivatives as potent RIPK1 kinase inhibitors	30
Sulfadoxine derivatization through multicomponent reactions to obtain new antiplasmodial compounds	30
Multiple approaches to repurposing drugs for neuroblastoma	29

RNA-templated chemical synthesis of proapoptotic L- and d-peptides	29
Janus dendritic ionizable lipids with fine designed headgroup and tails to improve mRNA delivery efficiency	28
Research progress of STAT3-based dual inhibitors for cancer therapy	28
Design, synthesis and antibacterial evaluation of oxazolidinone derivatives containing N-methylglycyl or quaternary ammonium salts	28
Design, synthesis and evaluation the bioactivities of novel 1,3-dimethyl-6-amino-1H-indazole derivatives as anticancer agents	28
Discovery of 3-hydroxymethyl-azetidine derivatives as potent polymerase theta inhibitors	27
Synthesis, evaluation of anti-breast cancer activity in vitro of ICS II derivatives and summary of the structure-activity relationship	26
Antimycobacterial and anti-inflammatory activities of thiourea derivatives focusing on treatment approaches for severe pulmonary tuberculosis	26
Design and evaluation of achiral, non-atropisomeric 4-(aminomethyl)phthalazin-1(2H)-one derivatives as novel PRMT5/MTA inhibitors	26
Peptide-based CE-SELEX enables convenient isolation of aptamers specifically recognizing CD20-expressing cells	26
Novel drug-like fluorenyl derivatives as selective butyrylcholinesterase and β-amyloid inhibitors for the treatment of Alzheimer’s disease	26
Combining CuAAC reaction enables sialylated Bi- and triantennary pseudo mannose N-glycans for investigating Siglec-7 interactions	25
Pentacyclic triterpene-amino acid derivatives induced apoptosis and autophagy in tumor cells, affected the JNK and PI3K/AKT/mTOR pathway	25
Graphical abstract TOC	24
Graphical abstract TOC	24
Design, synthesis, and antiviral activity of 1-aryl-4-arylmethylpiperazine derivatives as Zika virus inhibitors with broad antiviral spectrum	23
Design and evaluation of novel analogs of 2-amino-4-boronobutanoic acid (ABBA) as inhibitors of human gamma-glutamyl transpeptidase	23
More than forty years of nucleic acid structural science	23
Corrigendum to “Discovery of 1,3,4-oxadiazole derivatives as potential antitumor agents inhibiting the programmed cell death-1/programmed cell death-ligand 1 interaction” [Bioorg. Med. Chem. 46 (2021)	22
Editorial Board	22
Design, synthesis, and analgesia evaluation of novel Transient Receptor Potential Vanilloid 1 (TRPV1) agonists modified from Cannabidiol (CBD)	21
Contents continued	21
Graphical abstract TOC	21
1,3-Disubstituted-1,2,4-triazin-6-ones with potent activity against androgen receptor-dependent prostate cancer cells	21
Oligonucleotides containing 2′-O-methyl-5-(1-phenyl-1,2,3-triazol-4-yl)uridines demonstrate increased affinity for RNA and induce exon-skipping in vitro	21
Graphical abstract TOC	21
Graphical Abstract Contents Continued	21
Editorial Board	21
Graphical abstract TOC	21
Chemical similarities and differences among inhibitors of nitric oxide synthase, arginase and dimethylarginine dimethylaminohydrolase-1: Implications for the design of novel enzyme inhibitors modulati	21
Design, Synthesis, and biological evaluation of 7H-Pyrrolo[2,3-d]pyrimidines as potent HPK1 kinase inhibitors	20
CRBN ligand expansion for hematopoietic prostaglandin D2 synthase (H-PGDS) targeting PROTAC design and their in vitro ADME profiles	20
Design, synthesis and biological evaluation of novel indole derivatives as gut-selective NaPi2b inhibitors	20
Discovery of tetracyclic 1,2,4-triazoline-fused dibenzo[b,f][1,4]oxazepine as a potent anti-colorectal cancer agent with good efficacy and low toxicity	20
Structure activity relationship and target prediction for ABX464 analogues in Caenorhabditis elegans	20
Development of novel quinoline-NO donor hybrids inducing human breast cancer cells apoptosis via inhibition of topoisomerase I	20
A pharmacophore-based approach to demonstrating the scope of alcohol dehydrogenases	20
Current development and structure–activity relationship study of berberine derivatives	20
Concise synthesis of piperarborenine B	20
Synthesis and biological evaluation of O4′-benzyl-hispidol derivatives and analogs as dual monoamine oxidase-B inhibitors and anti-neuroinflammatory agents	19
Design, synthesis and biological evaluation of arylpropylamine derivatives as potential multi-target antidepressants	19
Quinazoline-based hydroxamic acid derivatives as dual histone methylation and deacetylation inhibitors for potential anticancer agents	19
Cytotoxicity of cinchona alkaloid organocatalysts against MES-SA and MES-SA/Dx5 multidrug-resistant uterine sarcoma cell lines	19
Assessing the rigidity of cubanes and bicyclo(1.1.1)pentanes as benzene bioisosteres	19
Directly arylated oligonucleotides as fluorescent molecular rotors for probing DNA single-nucleotide polymorphisms	18
Ligand- and structure-based identification of novel CDK9 inhibitors for the potential treatment of leukemia	18
Design, synthesis and biological evaluation of EGFR kinase inhibitors that spans the orthosteric and allosteric sites	18
(±)-Agrimonolide: Efficient synthesis and treatment of inflammatory bowel disease via JAK1/STAT3 pathway inhibition	18
Synthesis and mammalian cell compatibility of light-released glycan precursors for controlled metabolic engineering	18
Graphical abstract TOC	18

Hetero-aryl bromide precursor fluorine-18 radiosynthesis and preclinical evaluation of a novel positron emission tomography (PET) tracer [18F]GSK1482160	18
Editorial Board	18
Small phenolic inhibitors of PfATP6, a Plasmodium falciparum calcium ATPase, as prototype antimalarials	18
Editorial Board	17
The design of protozoan phosphoribosyltransferase inhibitors containing non-charged phosphate mimic residues	17
Discovery of SYD5115, a novel orally active small molecule TSH-R antagonist	17
Two distinct rotations of bithiazole DNA intercalation revealed by direct comparison of crystal structures of Co(III)•bleomycin A2 and B2 bound to duplex 5′-TAGTT sites	17
In Vivo Imaging of Tumor Hypoxia by Maintaining Green Fluorescence of 9-Aminoanthracene Under Hypoxic Conditions	17
4-Arylidene curcumin derivatives in vitro inhibit α-Synuclein aggregation and disaggregate the preformed fibril	17
Design and identification of brain-penetrant, potent, and selective 1,3-oxazole-based cholesterol 24-hydroxylase (CH24H) inhibitors	17
The 2022 Monkeypox outbreak: How the medicinal chemistry could help us?	17
Di-indenopyridines as topoisomerase II-selective anticancer agents: Design, synthesis, and structure–activity relationships	17
Graphical abstract TOC	17
Introduction of a carboxylic acid group into pyrazolylpyridine derivatives increased selectivity for inhibition of the 20-HETE synthase CYP4A11/4F2	17
In vivo imaging of fluorescent albumin modified with pyruvylated-human-type complex oligosaccharide reveals sialylation-like biodistribution and kinetics	17
Design and synthesis 1H-Pyrrolo[2,3-b]pyridine derivatives as FLT3 inhibitors for the treatment of Acute myeloid Leukemia	17
Inhibition of cytochrome bd oxidase in Mycobacterium tuberculosis by benzothiazole amides	16
Structure-activity relationships of middle-size cyclic peptides, KRAS inhibitors derived from an mRNA display	16
Design, synthesis and biological evaluation of phosphoroxy quinazoline derivatives as potential EGFRT790M/C797S inhibitors	16
Dihydroartemisinin improves hypercholesterolemia in ovariectomized mice via enhancing vectorial transport of cholesterol and bile acids from blood to bile	16
Identification of benzothiazole derived monosaccharides as potent, selective, and orally bioavailable inhibitors of human and mouse galectin-3; a rare example of using a S···O binding interaction for	16
Expanding antimicrobial chemotypes: indole-based DNA gyrase inhibitors with potential dual mechanism against multidrug-resistant bacteria	16
Novel trifluoromethylquinoline derivatives as potent tubulin polymerization inhibitors with antitumor activity	16
Biphenyl-based small molecule inhibitors: Novel cancer immunotherapeutic agents targeting PD-1/PD-L1 interaction	16
Fatty acid binding protein 5 inhibitors as novel anticancer agents against metastatic castration-resistant prostate cancer	16
A turn for the worse: Aβ β-hairpins in Alzheimer’s disease	16
A TNF-α blocking peptide that reduces NF-κB and MAPK activity for attenuating inflammation	15
Graphical abstract TOC	15
ClpP-based MtPTAC technology enables targeted degradation of inner mitochondrial membrane proteins	15
Structural optimization of naturally derived Ar-turmerone, as novel neuroinflammation suppressors effective in an Alzheimer mouse model	15
Design and synthesis of phenanthridinone and phenanthridine derivatives and their radiosensitizing activity	15
Thiazolidinones and related analogues as efficient antitrypanosomal agents	15
3-Amino-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carbonitrile: A fluorescent molecule that induces differentiation in PC12 cells	15
Discovery of pyrazolo[3,4-d]pyrimidines as novel mitogen-activated protein kinase kinase 3 (MKK3) inhibitors	15
Graphical abstract TOC	15
Editorial Board	15
Discovery and structure-activity relationship of Morita-Baylis-Hillman adducts as larvicides against dengue mosquito vector, Aedes aegypti (Diptera: Culicidae)	14
Graphical abstract TOC	14
Editorial Board	14
Structure-Activity relationship of 1-(Furan-2ylmethyl)Pyrrolidine-Based Stimulation-2 (ST2) inhibitors for treating graft versus host disease	14
Modulation of aryl hydrocarbon receptor activity by halogenated indoles	14
Exploring the interaction of N-(benzothiazol-2-yl)pyrrolamide DNA gyrase inhibitors with the GyrB ATP-binding site lipophilic floor: A medicinal chemistry and QTAIM study	14
Discovery and optimization of orally bioavailable and potent plasma Kallikrein inhibitors bearing a quaternary carbon	14
Generation of an RNA aptamer against LipL32 of Leptospira isolated by Tripartite-hybrid SELEX coupled with in-house Python-aided unbiased data sorting	14
Graphical Abstract TOC	14
Contents continued	14
Graphical abstract TOC	14
Discovery of structurally diverse diazatricyclododecenes as lysosomotropic autophagy inhibitors	14
Synthetic studies on the extracellular domain of the T cell immunoreceptor with immunoglobulin and immunoreceptor tyrosine-based inhibitory motif domain (TIGIT) using Trt-K10 solubilizing tags	14
Chemical design of radioiodinated probes with a metabolizable linkage for target-selective imaging of systemic amyloidosis	14
Exploring novel pyrazole-nitroimidazole hybrids: Synthesis and antiprotozoal activity against the human pathogen trichomonas vaginalis	14
Truxillic acid monoamides as fatty acid binding protein 5 inhibitors	14
Phenotypic screen identifies FOXO inhibitor to counteract maturation and promote expansion of human iPS cell-derived cardiomyocytes	14
Discovery of polymethoxyphenyl-pyridines bearing amino side chains as tubulin colchicine-binding site inhibitors	14
Discovery of novel hypoxia-activated, nitroimidazole constructed multi-target kinase inhibitors on the basis of AZD9291 for the treatment of human lung cancer	14
Synthesis and biological evaluation of indoline derivatives as CDGSH iron sulfur domain 2 activators	14
Structure-activity relationships of 2-pyrimidinecarbohydrazides as utrophin modulators for the potential treatment of Duchenne muscular dystrophy	13
Scaffold hopping and sidechain modification from a flavone scaffold lead to discovery of potent, selective CK2A2 inhibitors with favorable properties for CNS activity	13
Dimeric 1-(1H-indol-3-yl) urea as potent STING inhibitor to alleviate cisplatin-induced acute kidney injury in mice	13
Discovery of dual-targeted molecules based on Olaparib and Rigosertib for triple-negative breast cancer with wild-type BRCA	13
Fluorescent probes and degraders of the sterol transport protein Aster-A	13
Discovery of a potent C20-oxime pachysandra alkaloid analogue promising for treatment of hepatocellular carcinoma	13
Synthesis, biological activity and mechanism of action of novel allosecurinine derivatives as potential antitumor agents	13
Synthesis and biological evaluation of novel isobenzofuran-1(3H)-one derivatives as antidepressant agents	13
Stereoisomers of cannabidiols and their pharmacological activities – A potentially novel direction for cannabinoids	13
Influence of N-arylsulfonamido d-valine N-substituents on the selectivity and potency of matrix metalloproteinase inhibitors	13
Design, synthesis, docking, and biochemical characterization of non-nucleoside SARS-CoV-2 RdRp inhibitors	13
Design, synthesis and molecular modelling studies of bile acid-curcumin conjugates as potential antiproliferative agents for breast cancer	13
FDA-approved small molecule kinase inhibitors for cancer treatment (2001–2015): Medical indication, structural optimization, and binding mode Part I	13
An insight into the mechanistic role of (-)-Ampelopsin F from Vatica chinensis L. in inducing insulin secretion in pancreatic beta cells	13
Berberine improves liver injury induced glucose and lipid metabolic disorders via alleviating ER stress of hepatocytes and modulating gut microbiota in mice	12
Drug discovery targeting nicotinamide phosphoribosyltransferase (NAMPT): Updated progress and perspectives	12
Corrigendum to “Discovery of novel Quinazoline-based KRAS G12C inhibitors as potential anticancer agents” [Bioorg. Med. Chem. 71 (2022) 116962]	12
Synthesis and characterization of new acid-functionalized porphyrins displaying antimicrobial activity against gram positive bacteria, yeasts and filamentous fungi with or without ultra-high irradianc	12
Lead compound profiling for small molecule inhibitors of the REV1-CT/RIR Translesion synthesis Protein-Protein interaction	12
PET imaging of VEGFR and integrins in glioma tumor xenografts using 89Zr labelled heterodimeric peptide	12
Recent advances on synthesis and biological activities of C-17 aza-heterocycle derived steroids	12
Recent research progress of β-carbolines as privileged scaffold in the discovery of anticancer agent (2019–2024)	12
Editorial Board	12
Discovery and optimization of anthraquinone derivatives containing substituted bisbenzyloxy groups as a novel scaffold damaged endoplasmic reticulum and against hepatocellular carcinoma cells	12

Structure-activity relationship studies and biological properties evaluation of peptidic NRP-1 ligands: Investigation of N-terminal cysteine importance	12
Design, synthesis and in vitro validation of bivalent binders of SARS-CoV-2 spike protein: Obeticholic, betulinic and glycyrrhetinic acids as building blocks	12
Synthesis and antibacterial properties under blue LED light of conjugates between the siderophore desferrioxamine B (DFOB) and an Iridium(III) complex	12
Growth factors and their peptide mimetics for treatment of traumatic brain injury	12
Editorial Board	12
Structure-based design of a novel series of cholesterol 24-hydroxylase (CH24H) inhibitors bearing 1,3-oxazole as a heme–iron binding group	12
Editorial Board	12
Discovery of evodiamine derivatives as potent insecticide candidates	11
Design, synthesis, and biological evaluation of 2-arylamino-4-(piperidin-4-yloxy)pyrimidines as potent EGFRT790M/L858R inhibitors to treat non-small cell lung cancer	11
Graphical abstract TOC	11
Design of a potent and selective dual JAK1/TYK2 inhibitor	11
Editorial Board	11
Graphical abstract TOC	11
Design, synthesis and anti-tumor efficacy of novel phenyl thiazole/triazole derivatives as selective TrkA inhibitors	11
Synthesis and biophysical properties of tetravalent PEG-conjugated antisense oligonucleotide	11
Graphical abstract TOC	11
Design, synthesis, and evaluation of antipyrine and nicotinic acid derivatives as anti-inflammatory agents: in vitro and in vivo studies	11
Discovery and development of small-molecule heparanase inhibitors	11
Dual-responsive drug release and fluorescence imaging based on disulfide-pillar[4]arene aggregate in cancer cells	11
Elongation of N6-benzyladenosine scaffold via Pd-catalyzed C–C bond formation leads to derivatives with antiflaviviral activity	11
Structure-based lead optimization to improve potency and selectivity of a novel tetrahydroimidazo[1,2-a]pyridine-5-carboxylic acid series of heparanase-1 inhibitor	11
Editorial Board	11
Effect of helicity and hydrophobicity on cell-penetrating ability of arginine-rich peptides	11
Target discovery of bioactive natural products with native-compound-coupled CNBr-activated Sepharose 4B beads (NCCB): Applications, mechanisms and outlooks	11
Graphical abstract TOC	11
Strategic approaches to the discovery of biologically active indole derivatives: a comprehensive review	10
Design, synthesis, and pharmacological evaluation of N-(3-carbamoyl-1H-pyrazol-4-yl)-1,3-oxazole-4-carboxamide derivatives as interleukin-1 receptor-associated kinase 4 inhibitors with reduced potenti	10
Graphical abstract TOC	10
Graphical Abstract TOC	10
A special issue on artificial intelligence for drug discovery	10
Synthesis of 6-ethoxyphenyl 4-fluorobenzenesulfonate-tagged thiosemicarbazones as carbonic anhydrase inhibitors: In-vitro and in silico approach	10
Discovery and biological evaluation of novel dual PTP1B and ACP1 inhibitors for the treatment of insulin resistance	10
Potential COX-2 inhibitors modulating NF-κB/MAPK signaling pathways: Design, synthesis and evaluation of anti-inflammatory activity of Pterostilbene-carboxylic acid derivatives with an oxime ether moi	10
The most common linkers in bioactive molecules and their bioisosteric replacement network	10
Thiazolidinedione-based structure modification of ergosterol peroxide provides thiazolidinedione-conjugated derivatives as potent agents against breast cancer cells through a PI3K/AKT/mTOR pathway	10
Structure activity relationships leading to the identification of the indirect activator of AMPK, R419	10
Graphical abstract TOC	10
Design, synthesis and anti-rheumatoid arthritis activity of target TLR4 inhibitors	10
Natural scaffold, modern strategy: Coumarin hybrids as potential carbohydrate-digesting enzyme inhibitors-A decade of medicinal chemistry exploration (2015–2025)	10
Synthesis of 1,8-cineole derivatives and evaluation of their cytoprotective effects against cisplatin-induced HK-2 cell injury	10
Evaluation of potential anticonvulsant fluorinated N-benzamide enaminones as T-type Ca2+ channel blockers	10
Biocompatible conjugated polymer nanoparticles labeled with 225Ac for tumor endoradiotherapy	10
Exploration of 1,2,3-triazole linked benzenesulfonamide derivatives as isoform selective inhibitors of human carbonic anhydrase	10
Synthesis of sp3-rich chiral bicyclo[3.3.1]nonanes for chemical space expansion and study of biological activities	10
Design, synthesis, and bioactivity study on Lissodendrins B derivatives as PARP1 inhibitor	10
Inhibition of the hERG potassium ion channel by different non-nucleoside human cytomegalovirus polymerase antiviral inhibitor series and the exploration of variations on a pyrroloquinoline core to red	10
Rational design of AIEgens through π-bridge engineering for dual-modal photodynamic and photothermal therapy	10
Selenoneine-inspired selenohydantoins with glutathione peroxidase-like activity	10
Synthesis and biological evaluation of 4H-benzo[e][1,3]oxazin-4-ones analogues of TGX-221 as inhibitors of PI3Kβ	10
Synthesis and biological evaluation of sulfonylpyridine derivatives as potential anti-chlamydia agents	9
Discovery and characterization of a high-affinity G-quadruplex binding peptide via mRNA display	9
Editorial Board	9
Targeting the PI3K/mTOR pathway in idiopathic pulmonary fibrosis: Advances and therapeutic potential	9
Drug discovery targeting protein arginine methyltransferase 5 (PRMT5): an update	9
Recent applications of seven-membered rings in drug design	9
Design and synthesis of sulfonamides incorporating a biotin moiety: Carbonic anhydrase inhibitory effects, antiproliferative activity and molecular modeling studies	9
Indole derivatives as tubulin polymerization inhibitors for the development of promising anticancer agents	9
Harnessing polyhydroxylated pyrrolidines as a stabilizer of acid alpha-glucosidase (GAA) to enhance the efficacy of enzyme replacement therapy in Pompe disease	9
Synthesis and biological evaluation of aminobenzamides containing purine moiety as class I histone deacetylases inhibitors	9
Design, synthesis and biological evaluation of 3-arylisoquinoline derivatives as topoisomerase IIα inhibitors for the therapy of small cell lung cancer	9
A critical update on the strategies towards small molecule inhibitors targeting Serine/arginine-rich (SR) proteins and Serine/arginine-rich proteins related kinases in alternative splicing	9
Discovery, Topo I inhibitory activity and mechanism evaluation of two novel cytisine-type alkaloid dimers from the seeds of Sophora alopecuroides L	9
New phenylpiperazine-thiazolidine-2,4-dione hybrids targeting MAO inhibition: Synthesis, biological evaluation, kinetic study and in silico insights	9
Suramin analogues protect cartilage against osteoarthritic breakdown by increasing levels of tissue inhibitor of metalloproteinases 3 (TIMP-3) in the tissue	9
Design, in silico study, and efficient synthesis of N-acylhydrazones in deep eutectic solvents: potential anticonvulsant agents	9
Design, synthesis, and biological evaluation of a potential long-acting glucagon-like peptide-1 (GLP-1) analog	9
Quinolinetrione-tacrine hybrids as multi-target-directed ligands against Alzheimer's disease	9
Discovery of CN0 as a novel proteolysis-targeting chimera (PROTAC) degrader of PARP1 that can activate the cGAS/STING immunity pathway combined with daunorubicin	9
Engineered B7-H3-targeted VHH-Fc fusion antibody demonstrates rapid tumor accumulation for infrared imaging in pancreatic cancer xenograft model	9
Glutathione-responsive PROTAC for targeted degradation of ERα in breast cancer cells	9
Synthesis and biological evaluation of hybrids from optically active ring-opened 3-N-butylphthalide derivatives and 4-fluro-edaravone as potential anti-acute ischemic stroke agents	9
Discovery of Pyrazolo[1,5-a]pyrazin-4-ones as Potent and Brain Penetrant GluN2A-Selective Positive Allosteric Modulators Reducing AMPA Receptor Binding Activity	9
Advances in the development of Rho GTPase inhibitors	9
Discovery of pyrido[4,3-d]pyrimidinone derivatives as novel Wee1 inhibitors	9
Tenuistones A–H, novel flavonoid derivatives from Miliusa tenuistipitata with anti-proliferative and anti-migration activities against triple-negative breast cancer cells	9
Discovery of acetohydroxyacid synthase inhibitors as anti-tuberculosis lead compounds from natural products	9
Synthesis and antimicrobial studies of cadasides analogues via on-resin esterification	9
Graphical abstract TOC	9
Editorial Board	9
Editorial Board	9
Design, classification, and adverse effects of NSAIDs: A review on recent advancements	9
Graphical abstract TOC	9
Identification of potent α-amylase inhibitors via dynamic combinatorial chemistry	9
Discovery of novel 3-butyl-6-benzyloxyphthalide Mannich base derivatives as multifunctional agents against Alzheimer's disease	9
Exogenous/endogenous stimuli-responsive antitumor prodrugs advance precision chemotherapy	9
RAD18-catalysed formation of ubiquitination intermediate mimic of proliferating cell nuclear antigen PCNA	9
Virtual screening, synthesis, optimization and anti-inflammatory activity of novel chromones as specific COX-2 inhibitors	9
Corylin induces UGT1A1 via PPARs/AhR and exerts hepatoprotection in mice	9
Saturation transfer difference (STD)-NMR spectroscopy in drug discovery: A comprehensive review on identified potential hits based on natural and synthetic scaffolds against therapeutic drug targets	9
Discovery of ASP5878: Synthesis and structure–activity relationships of pyrimidine derivatives as pan-FGFRs inhibitors with improved metabolic stability and suppressed hERG channel inhibitory activity	8
Design and synthesis of boron-containing ALK inhibitor with favorable in vivo efficacy	8
Structure activity relationship of pyrazinoic acid analogs as potential antimycobacterial agents	8
Silybins are stereospecific regulators of the 20S proteasome	8
The application of PROTACs in immune-inflammation diseases	8
Revisiting recent unusual drug-DNA complex structures: Implications for cancer and neurological disease diagnostics and therapeutics	8