OOIR: Observatory of International Research

Papers

(The median citation count of Angiogenesis is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
A novel somatic mutation in GNAQ in a capillary malformation provides insight into molecular pathogenesis	184
Endothelial heterogeneity and plasticity	135
Embracing Imatinib: a novel approach to safeguarding the endothelial barrier in patients with COVID-19	107
Damage to endothelial barriers and its contribution to long COVID	78
Role of Notch in endothelial biology	71
Aging impairs the ability of vascular endothelial stem cells to generate endothelial cells in mice	67
Human atherosclerotic plaque transcriptomics reveals endothelial beta-2 spectrin as a potential regulator a leaky plaque microvasculature phenotype	63
Generation and characterisation of scalable and stable human pluripotent stem cell-derived microvascular-like endothelial cells for cardiac applications	63
Unique functions for Notch4 in murine embryonic lymphangiogenesis	53
Lactate secreted by glycolytic conjunctival melanoma cells attracts and polarizes macrophages to drive angiogenesis in zebrafish xenografts	49
Refractory systemic capillary leak syndrome treated with bevacizumab: a case report	45
Granzyme B degrades extracellular matrix and promotes inflammation and choroidal neovascularization	37
A streamlined method to generate endothelial cells from human pluripotent stem cells via transient doxycycline-inducible ETV2 activation	37
Senescent endothelial cells: a potential target for diabetic retinopathy	34
Somatic GJA4 gain-of-function mutation in orbital cavernous venous malformations	33
Inhibition of the prolyl isomerase Pin1 improves endothelial function and attenuates vascular remodelling in pulmonary hypertension by inhibiting TGF-β signalling	33
ACVR1/ALK2-p21 signaling axis modulates proliferation of the venous endothelium in the retinal vasculature	33
Correction: Human iPSC and CRISPR targeted gene knock-in strategy for studying the somatic TIE2L914F mutation in endothelial cells	32
Modeling angiogenesis in the human brain in a tissue-engineered post-capillary venule	32
Vascular mimicry in zebrafish fin regeneration: how macrophages build new blood vessels	32
Correction: Persistent endothelial dysfunction in post-COVID-19 syndrome and its associations with symptom severity and chronic inflammation	32
Phenotypic screening in Organ-on-a-Chip systems: a 1537 kinase inhibitor library screen on a 3D angiogenesis assay	28
Design and preclinical evaluation of a novel apelin-based PET radiotracer targeting APJ receptor for molecular imaging of angiogenesis	26
Blood flow regulates acvrl1 transcription via ligand-dependent Alk1 activity	26
The vascularization paradox of non-union formation	26

In vitro grafting of hepatic spheroids and organoids on a microfluidic vascular bed	24
Correction to: Notch regulates vascular collagen IV basement membrane through modulation of lysyl hydroxylase 3 trafficking	23
Differential endothelial cell cycle status in postnatal retinal vessels revealed using a novel PIP-FUCCI reporter and zonation analysis	22
CCL4 contributes to aging related angiogenic insufficiency through activating oxidative stress and endothelial inflammation	22
Executive summary of the 14th HHT international scientific conference	20
Opposite response of lung adenocarcinoma and its choroidal metastases upon ramucirumab plus docetaxel therapy after immunotherapy: a case report	20
Systemic glucocorticoids link to long-term microvascular injury in COVID-19	18
On coalescent angiogenesis and the remarkable flexibility of blood vessels	18
Von Willebrand factor multimers during non-invasive ultrasound therapy for aortic valve stenosis	17
Von Willebrand factor collagen-binding capacity predicts in-hospital mortality in COVID-19 patients: insight from VWF/ADAMTS13 ratio imbalance	17
Correction: Mitochondrial control of hypoxia-induced pathological retinal angiogenesis	17
KIT is dispensable for physiological organ vascularisation in the embryo	16
PDPN/CCL2/STAT3 feedback loop alter CAF heterogeneity to promote angiogenesis in colorectal cancer	16
Circulating Von Willebrand factor: a consistent biomarker predicting in-hospital mortality across different waves of the COVID-19 pandemic	16
Plasma ratio of angiopoietin-2 to angiopoietin-1 is a biomarker of vascular impairment in chronic obstructive pulmonary disease patients	15
Blood vessels sense dermal stiffness via a novel mechanotransducer, APJ	15
The role of vasculature and angiogenesis in respiratory diseases	14
Correction to: BI1 is associated with microvascular protection in cardiac ischemia reperfusion injury via repressing Syk-Nox2-Drp1-mitochondrial fission pathways	14
Navigating tumor angiogenesis: therapeutic perspectives and myeloid cell regulation mechanism	14
Oscillatory contractile forces refine endothelial cell-cell interactions for continuous lumen formation governed by Heg1/Ccm1	14
People with a connective tissue disorder may be especially vulnerable to the endothelial damage that characterizes long COVID due to the fragility of their vasculature and slow wound healing	14
Localized conditional induction of brain arteriovenous malformations in a mouse model of hereditary hemorrhagic telangiectasia	14
TFEB controls integrin-mediated endothelial cell adhesion by the regulation of cholesterol metabolism	14
Copper stress impairs angiogenesis and lymphangiogenesis during zebrafish embryogenesis by down-regulating pERK1/2-foxm1-MMP2/9 axis and epigenetically regulating ccbe1 expression	14
Botulinum neurotoxin serotype A inhibited ocular angiogenesis through modulating glial activation via SOCS3	14
Microvascular and proteomic signatures overlap in COVID-19 and bacterial sepsis: the MICROCODE study	13
Angiogenesis in adipose tissue and obesity	12
Resident vascular endothelial progenitor definition and function: the age of reckoning	12
Circulating endothelial cells: a key biomarker of persistent fatigue after hospitalization for COVID-19	12
The endosomal RIN2/Rab5C machinery prevents VEGFR2 degradation to control gene expression and tip cell identity during angiogenesis	11
Molecular mechanisms of coronary microvascular endothelial dysfunction in diabetes mellitus: focus on mitochondrial quality surveillance	11
Identification of vascular cues contributing to cancer cell stemness and function	11
Breathing new life into tissue engineering: exploring cutting-edge vascularization strategies for skin substitutes	11
Sialyl Lewis X decorated integrin α3 on small extracellular vesicles promotes metastasis of bladder cancer via enhancing vascular permeability	10
The rising impact of angiogenesis research	10
Vascularized organoid-on-a-chip: design, imaging, and analysis	10
Role of TGFβ1 and WNT6 in FGF2 and BMP4-driven endothelial differentiation of murine embryonic stem cells	10
NRASQ61R mutation in human endothelial cells causes vascular malformations	9
Effect of oral nintedanib vs placebo on epistaxis in hereditary hemorrhagic telangiectasia: the EPICURE multicenter randomized double-blind trial	9
Pathological angiogenesis: mechanisms and therapeutic strategies	9
Anti-angiogenic therapy as potential treatment for adenomyosis	9
Pericyte hypoxia-inducible factor-1 (HIF-1) drives blood-brain barrier disruption and impacts acute ischemic stroke outcome	9
Adieu to parting Editor in Chief and pioneering scientist Dr. Joyce Bischoff	9
Extracellular matrix stiffness controls VEGF165 secretion and neuroblastoma angiogenesis via the YAP/RUNX2/SRSF1 axis	9
Ref-1 is overexpressed in neovascular eye disease and targetable with a novel inhibitor	8
2022 14th HHT International Scientific Conference Abstracts	8
Correction: The angiogenesis suppressor gene AKAP12 is under the epigenetic control of HDAC7 in endothelial cells	8
Proinflammatory activity of VEGF-targeted treatment through reversal of tumor endothelial cell anergy	7
Inhibition of Angiopoietin-2 rescues sporadic brain arteriovenous malformations by reducing pericyte loss	7
Protein disulfide isomerase A1 as a novel redox sensor in VEGFR2 signaling and angiogenesis	7

Targeting SMYD2 inhibits angiogenesis and increases the efficiency of apatinib by suppressing EGFL7 in colorectal cancer	7
Inflammasome activation aggravates choroidal neovascularization	7
A C-type lectin from Bothrops jararacussu venom reprograms endothelial cell biology	7
Expansion and collapse of VEGF diversity in major clades of the animal kingdom	7
MicroRNA-375 repression of Kruppel-like factor 5 improves angiogenesis in diabetic critical limb ischemia	7
Neuropilin-1 controls vascular permeability through juxtacrine regulation of endothelial adherens junctions	7
The dynamics of the endothelial glycocalyx: a rare snapshot by electron microscopy	7
Group XIV C-type lectins: emerging targets in tumor angiogenesis	6
IC100, a humanized therapeutic monoclonal anti-ASC antibody alleviates oxygen-induced retinopathy in mice	6
Somatic BrafV600E mutation in the cerebral endothelium induces brain arteriovenous malformations	6
Soluble FLT-1 in angiogenesis: pathophysiological roles and therapeutic implications	6
PHD2 deletion in endothelial or arterial smooth muscle cells reveals vascular cell type-specific responses in pulmonary hypertension and fibrosis	5
Vascular endothelial cell specification in health and disease	5
Role of endothelial PDGFB in arterio-venous malformations pathogenesis	5
Similarities and differences between brain and skin GNAQ p.R183Q driven capillary malformations	5
Targeting the microenvironment in the treatment of arteriovenous malformations	5
Capillary morphogenesis gene 2 (CMG2) mediates growth factor-induced angiogenesis by regulating endothelial cell chemotaxis	5
Angiopoietin-2-induced lymphatic endothelial cell migration drives lymphangiogenesis via the β1 integrin-RhoA-formin axis	5