OOIR: Observatory of International Research

Papers

(The TQCC of Angiogenesis is 15. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)

Article	Citations
Granzyme B degrades extracellular matrix and promotes inflammation and choroidal neovascularization	271
Blood flow regulates acvrl1 transcription via ligand-dependent Alk1 activity	86
Senescent endothelial cells: a potential target for diabetic retinopathy	78
Role of TGFβ1 and WNT6 in FGF2 and BMP4-driven endothelial differentiation of murine embryonic stem cells	75
The role of vasculature and angiogenesis in respiratory diseases	62
Copper stress impairs angiogenesis and lymphangiogenesis during zebrafish embryogenesis by down-regulating pERK1/2-foxm1-MMP2/9 axis and epigenetically regulating ccbe1 expression	59
People with a connective tissue disorder may be especially vulnerable to the endothelial damage that characterizes long COVID due to the fragility of their vasculature and slow wound healing	47
Somatic BrafV600E mutation in the cerebral endothelium induces brain arteriovenous malformations	40
The vascular gene Apold1 is dispensable for normal development but controls angiogenesis under pathological conditions	37
Proinflammatory activity of VEGF-targeted treatment through reversal of tumor endothelial cell anergy	33
Soluble FLT-1 in angiogenesis: pathophysiological roles and therapeutic implications	33
Alk1/Endoglin signaling restricts vein cell size increases in response to hemodynamic cues	32
BMP10 functions independently from BMP9 for the development of a proper arteriovenous network	31
PDGFD switches on stem cell endothelial commitment	29
Coalescent angiogenesis—evidence for a novel concept of vascular network maturation	29
Nectins and Nectin-like molecules drive vascular development and barrier function	28
In vivo dissection of Rhoa function in vascular development using zebrafish	27
Endothelial cells require functional FLVCR1a during developmental and adult angiogenesis	27
Multimodality imaging reveals angiogenic evolution in vivo during calvarial bone defect healing	27
Persistent endothelial dysfunction in post-COVID-19 syndrome and its associations with symptom severity and chronic inflammation	27
FGF21 via mitochondrial lipid oxidation promotes physiological vascularization in a mouse model of Phase I ROP	25
Impact of heterozygous ALK1 mutations on the transcriptomic response to BMP9 and BMP10 in endothelial cells from hereditary hemorrhagic telangiectasia and pulmonary arterial hypertension donors	25
Correction: Celecoxib and octreotide synergistically ameliorate portal hypertension via inhibition of angiogenesis in cirrhotic rats	22
Diminished vasculogenesis under inflammatory conditions is mediated by Activin A	22
Persistent capillary rarefication in long COVID syndrome	21

Vascular mimicry in zebrafish fin regeneration: how macrophages build new blood vessels	21
On coalescent angiogenesis and the remarkable flexibility of blood vessels	19
Blood vessels sense dermal stiffness via a novel mechanotransducer, APJ	19
Localized conditional induction of brain arteriovenous malformations in a mouse model of hereditary hemorrhagic telangiectasia	18
KIT is dispensable for physiological organ vascularisation in the embryo	18
CCL4 contributes to aging related angiogenic insufficiency through activating oxidative stress and endothelial inflammation	17
Effect of oral nintedanib vs placebo on epistaxis in hereditary hemorrhagic telangiectasia: the EPICURE multicenter randomized double-blind trial	17
The rising impact of angiogenesis research	17
Capillary morphogenesis gene 2 (CMG2) mediates growth factor-induced angiogenesis by regulating endothelial cell chemotaxis	16
Similarities and differences between brain and skin GNAQ p.R183Q driven capillary malformations	16
MicroRNA-375 repression of Kruppel-like factor 5 improves angiogenesis in diabetic critical limb ischemia	15
Reply to “Embracing imatinib: a novel approach to safeguarding the endothelial barrier in patients with COVID-19”	15
Inhibition of Angiopoietin-2 rescues sporadic brain arteriovenous malformations by reducing pericyte loss	15
Endothelial cell expression of mutant Map2k1 causes vascular malformations in mice	15
Role of endothelial PDGFB in arterio-venous malformations pathogenesis	15
Site-specific genetic and functional signatures of aortic endothelial cells at aneurysm predilection sites in healthy and AngII ApoE−/− mice	15