OOIR: Observatory of International Research

Papers

(The H4-Index of Neurobiology of Disease is 44. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)

Article	Citations
Aberrant splicing of mutant huntingtin in Huntington's disease knock-in pigs	166
Estrogen-related receptor gamma is a regulator of mitochondrial, autophagy, and immediate-early gene programs in spiny projection neurons: Relevance for transcriptional changes in Huntington disease	127
The predictive value of mBDNF for major adverse cardiovascular events in stable coronary artery disease patients with depressive symptoms: A single-center, 5-year follow-up study	108
The neoliberal leaning of the neuroscience discourse when it deals with mental health and learning disorders	101
CCR5 deficiency normalizes TIMP levels, working memory, and gamma oscillation power in APOE4 targeted replacement mice	94
Amyloid beta peptides (Aβ) from Alzheimer's disease neuronal secretome induce endothelial activation in a human cerebral microvessel model	93
New perspectives on the role of biological factors in anorexia nervosa: Brain volume reduction or oxidative stress, which came first?	92
Cellular iron deposition patterns predict clinical subtypes of multiple system atrophy	86
Key role of the gut–microbiota–brain axis via the subdiaphragmatic vagus nerve in demyelination of the cuprizone-treated mouse brain	76
Nicotinamide riboside modulates the reactive species interactome, bioenergetic status and proteomic landscape in a brain-region-specific manner	74
Gut-brain axis in the pathogenesis of sepsis-associated encephalopathy	73
Stem cell therapy for central nervous system disorders: Metabolic interactions between transplanted cells and local microenvironments	73
Interhemispheric reactivity of the subthalamic nucleus sustains progressive dopamine neuron loss in asymmetrical parkinsonism	69
Brain organoid models for studying the function of iPSC-derived microglia in neurodegeneration and brain tumours	69
MicroRNA signature of lymphoblasts from amyotrophic lateral sclerosis patients as potential clinical biomarkers	65
Intermittent fasting produces antidepressant-like effects by modulating dopamine D1 receptors in the medial prefrontal cortex	65
Caffeine consumption outcomes on amyotrophic lateral sclerosis disease progression and cognition	60
Serotonin innervation of the subthalamic nucleus in parkinsonian monkeys	60
Diagnostic and prognostic value of the RUNXOR/RUNX1 axis in multiple sclerosis	59
Evoked resonant neural activity in subthalamic local field potentials reflects basal ganglia network dynamics	58
The altered sensitivity of acute stress induced anxiety-related behaviors by modulating insular cortex-paraventricular thalamus-bed nucleus of the stria terminalis neural circuit	58
T cell infiltration mediates neurodegeneration and cognitive decline in Alzheimer's disease	57
Perturbation of serine enantiomers homeostasis in the striatum of MPTP-lesioned monkeys and mice reflects the extent of dopaminergic midbrain degeneration	56
The association of epigenetic clocks in brain tissue with brain pathologies and common aging phenotypes	56
Identification of an epilepsy-linked gut microbiota signature in a pediatric rat model of acquired epilepsy	56

Plasma lysosphingolipids in GRN-related diseases: Monitoring lysosomal dysfunction to track disease progression	55
Postnatal Foxp2 regulates early psychiatric-like phenotypes and associated molecular alterations in the R6/1 transgenic mouse model of Huntington's disease	55
A novel role for the ADHD risk gene latrophilin-3 in learning and memory in Lphn3 knockout rats	55
Early suppression of excitability in subcortical band heterotopia modifies epileptogenesis in rats	54
Inflammation in dementia with Lewy bodies	54
Sunitinib-mediated inhibition of STAT3 in skeletal muscle and spinal cord does not affect the disease in a mouse model of ALS	54
Potential clinical and biochemical markers for the prediction of drug-resistant epilepsy: A literature review	53
Protective Alzheimer's disease-associated APP A673T variant predominantly decreases sAPPβ levels in cerebrospinal fluid and 2D/3D cell culture models	52
Sphingosine 1-phosphate receptor subtype 1 (S1P1) activity in the course of Alzheimer's disease	51
Neonatal stroke enhances interaction of microglia-derived extracellular vesicles with microglial cells	51
14-3-3θ phosphorylation exacerbates alpha-synuclein aggregation and toxicity	51
Shaping down syndrome brain cognitive and molecular changes due to aging using adult animals from the Ts66Yah murine model	50
Alternative platelet activation pathways and their role in neurodegenerative diseases	50
Neuronal hyperexcitability and ion channel dysfunction in CDKL5-deficiency patient iPSC-derived cortical organoids	47
Epm2aR240X knock-in mice present earlier cognitive decline and more epileptic activity than Epm2a mice	47
General loss of proteostasis links Huntington disease to Cockayne syndrome	46
Neuronal MeCP2 in the dentate gyrus regulates mossy fiber sprouting of mice with temporal lobe epilepsy	46
Ischemic brain edema: Emerging cellular mechanisms and therapeutic approaches	45
Altered static and dynamic functional connectivity of the default mode network across epilepsy subtypes in children: A resting-state fMRI study	44
Increased propensity for infantile spasms and altered neocortical excitation-inhibition balance in a mouse model of down syndrome carrying human chromosome 21	44
Epigenomic analysis of Alzheimer's disease brains reveals diminished CTCF binding on genes involved in synaptic organization	44
Corrigendum to “Upregulation of tripeptidyl-peptidase 1 by 3-hydroxy-(2,2)-dimethyl butyrate, a brain endogenous ligand of PPARα: Implications for late-infantile Batten disease therapy” [Neurobiology	44