OOIR: Observatory of International Research

Papers

(The TQCC of Cell Research is 62. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-04-01 to 2024-04-01.)

Article	Citations
Interaction between microbiota and immunity in health and disease	1701
Ferroptosis: molecular mechanisms and health implications	1394
Boceprevir, GC-376, and calpain inhibitors II, XII inhibit SARS-CoV-2 viral replication by targeting the viral main protease	635
Immune checkpoint signaling and cancer immunotherapy	590
The future of cancer immunotherapy: microenvironment-targeting combinations	453
A pan-cancer blueprint of the heterogeneous tumor microenvironment revealed by single-cell profiling	366
Manganese is critical for antitumor immune responses via cGAS-STING and improves the efficacy of clinical immunotherapy	352
AXL is a candidate receptor for SARS-CoV-2 that promotes infection of pulmonary and bronchial epithelial cells	343
COVID-19: towards understanding of pathogenesis	252
SARS-CoV-2 infects human neural progenitor cells and brain organoids	250
SARS-CoV-2 spike protein interacts with and activates TLR41	216
RAB31 marks and controls an ESCRT-independent exosome pathway	209
Discriminating mild from critical COVID-19 by innate and adaptive immune single-cell profiling of bronchoalveolar lavages	209
Metabolic signaling in T cells	185
Single-cell transcriptomics reveals regulators underlying immune cell diversity and immune subtypes associated with prognosis in nasopharyngeal carcinoma	182
Elimination of senescent cells by β-galactosidase-targeted prodrug attenuates inflammation and restores physical function in aged mice	181
Calreticulin and cancer	176
Infection with novel coronavirus (SARS-CoV-2) causes pneumonia in Rhesus macaques	166
Pathological evidence for residual SARS-CoV-2 in pulmonary tissues of a ready-for-discharge patient	165
Coinfection with influenza A virus enhances SARS-CoV-2 infectivity	159
The ChinaMAP analytics of deep whole genome sequences in 10,588 individuals	159
Three-dimensional bioprinted glioblastoma microenvironments model cellular dependencies and immune interactions	146
SARS-CoV-2 Omicron variant is highly sensitive to molnupiravir, nirmatrelvir, and the combination	144
The metabolite α-KG induces GSDMC-dependent pyroptosis through death receptor 6-activated caspase-8	142
Transcriptional and epigenetic basis of Treg cell development and function: its genetic anomalies or variations in autoimmune diseases	141

863 genomes reveal the origin and domestication of chicken	137
Molecular subtyping and genomic profiling expand precision medicine in refractory metastatic triple-negative breast cancer: the FUTURE trial	133
Whole-genome sequencing of 508 patients identifies key molecular features associated with poor prognosis in esophageal squamous cell carcinoma	124
Liquid–liquid phase separation by SARS-CoV-2 nucleocapsid protein and RNA	123
A novel receptor-binding domain (RBD)-based mRNA vaccine against SARS-CoV-2	121
Humoral immune response to circulating SARS-CoV-2 variants elicited by inactivated and RBD-subunit vaccines	119
Innate lymphoid cells control signaling circuits to regulate tissue-specific immunity	111
A COVID-19 mRNA vaccine encoding SARS-CoV-2 virus-like particles induces a strong antiviral-like immune response in mice	111
The basis of a more contagious 501Y.V1 variant of SARS-CoV-2	110
Single-cell transcriptomic analysis defines the interplay between tumor cells, viral infection, and the microenvironment in nasopharyngeal carcinoma	106
Old dogs, new trick: classic cancer therapies activate cGAS	103
Homotypic clustering of L1 and B1/Alu repeats compartmentalizes the 3D genome	99
SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target	96
Receptome profiling identifies KREMEN1 and ASGR1 as alternative functional receptors of SARS-CoV-2	95
Tissue-specific transcriptional imprinting and heterogeneity in human innate lymphoid cells revealed by full-length single-cell RNA-sequencing	94
The m6A methylome of SARS-CoV-2 in host cells	94
Mining of epitopes on spike protein of SARS-CoV-2 from COVID-19 patients	93
Transdifferentiation of tumor infiltrating innate lymphoid cells during progression of colorectal cancer	90
Mucus production stimulated by IFN-AhR signaling triggers hypoxia of COVID-19	89
Reconstruction of cell spatial organization from single-cell RNA sequencing data based on ligand-receptor mediated self-assembly	88
Degradation of lipid droplets by chimeric autophagy-tethering compounds	88
A cohort autopsy study defines COVID-19 systemic pathogenesis	88
Reduced interferon antagonism but similar drug sensitivity in Omicron variant compared to Delta variant of SARS-CoV-2 isolates	86
25-Hydroxycholesterol is a potent SARS-CoV-2 inhibitor	86
Single-cell transcriptomic atlas of primate cardiopulmonary aging	81
Single-cell transcriptomic analysis of somatosensory neurons uncovers temporal development of neuropathic pain	81
The SARS-CoV-2 spike protein: balancing stability and infectivity	80
Dalbavancin binds ACE2 to block its interaction with SARS-CoV-2 spike protein and is effective in inhibiting SARS-CoV-2 infection in animal models	79
Kinetics and mechanisms of mitotic inheritance of DNA methylation and their roles in aging-associated methylome deterioration	79
Structural basis for the different states of the spike protein of SARS-CoV-2 in complex with ACE2	77
Molecular basis for ligand activation of the human KCNQ2 channel	76
High-resolution mapping of mitotic DNA synthesis regions and common fragile sites in the human genome through direct sequencing	75
Cryo-EM structures of inactive and active GABAB receptor	74
Structural basis for nucleosome-mediated inhibition of cGAS activity	73
Mesenchymal stem cell treatment improves outcome of COVID-19 patients via multiple immunomodulatory mechanisms	73
Structure-based development of human antibody cocktails against SARS-CoV-2	72
Engineered trimeric ACE2 binds viral spike protein and locks it in “Three-up” conformation to potently inhibit SARS-CoV-2 infection	72
Recombinant protein subunit vaccine booster following two-dose inactivated vaccines dramatically enhanced anti-RBD responses and neutralizing titers against SARS-CoV-2 and Variants of Concern	72
Design and development of an oral remdesivir derivative VV116 against SARS-CoV-2	71
Rational development of a human antibody cocktail that deploys multiple functions to confer Pan-SARS-CoVs protection	71
A phosphatidic acid-binding lncRNA SNHG9 facilitates LATS1 liquid–liquid phase separation to promote oncogenic YAP signaling	70
Enhancing prime editing by Csy4-mediated processing of pegRNA	70
Resolving individual atoms of protein complex by cryo-electron microscopy	68
Wnt signaling and Loxl2 promote aggressive osteosarcoma	66
Dysregulated adaptive immune response contributes to severe COVID-19	66
O-glycosylation pattern of the SARS-CoV-2 spike protein reveals an “O-Follow-N” rule	66
SIDT1-dependent absorption in the stomach mediates host uptake of dietary and orally administered microRNAs	66
Humoral immunogenicity and reactogenicity of CoronaVac or ZF2001 booster after two doses of inactivated vaccine	65
Oncogenic AURKA-enhanced N6-methyladenosine modification increases DROSHA mRNA stability to transactivate STC1 in breast cancer stem-like cells	65
Binding pathway determines norepinephrine selectivity for the human β1AR over β2AR	62

Neddylation of PTEN regulates its nuclear import and promotes tumor development	62
SARS-CoV-2 promotes RIPK1 activation to facilitate viral propagation	62
Stabilization of heterochromatin by CLOCK promotes stem cell rejuvenation and cartilage regeneration	62
Pulmonary alveolar regeneration in adult COVID-19 patients	62
Pericytes augment glioblastoma cell resistance to temozolomide through CCL5-CCR5 paracrine signaling	62