OOIR: Observatory of International Research

Papers

(The median citation count of Brain Pathology is 1. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Variable histopathology features of neuronal dyslamination in the cerebral neocortex adjacent to epilepsy‐associated vascular malformations suggest complex pathogenesis of focal cortical dysplasia ILA	137
A 29‐year‐old man with a right intracranial mass	95
A 71‐year‐old female with an intrasellar mass	90
Society News	79
Issue Information	77
Issue Information	67
	62
Acknowledgement to Reviewer	60
Peripheral blood‐derived immune cell counts as prognostic indicators and their relationship with DNA methylation subclasses in glioblastoma patients	57
A 53‐year‐old female with suprasellar mass	44
Left dural‐based mass in a 62‐year‐old female	43
Issue Information	42
Exploiting nanopore sequencing for characterization and grading of IDH‐mutant gliomas	41
A 53‐year‐old man with a 16‐year history of asymmetrical proximal muscle weakness, facial muscle weakness, and scapular winging	40
A diffuse glioma with oligodendroglial‐like cells and extensive calcifications	38
A tribute to John Q. Trojanowski (1946–2022), neuropathologist extraordinaire	33
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Society News	29
Recent data and developments in myositis	28
An 82‐year‐old man with a right frontal lobe rim‐enhancing lesion	26
Multiple intra‐axial lesions in a 57‐year‐old male with a history of B‐cell chronic lymphocytic leukemia	25
The post‐stroke young adult brain has limited capacity to re‐express the gene expression patterns seen during early postnatal brain development	25
Astrocyte‐derived Interleukin‐31 causes poor prognosis in elderly patients with intracerebral hemorrhage	25
SPI1 activates TGF‐β1/PI3K/Akt signaling through transcriptional upregulation of FKBP12 to support the mesenchymal phenotype of glioma stem cells	24
MET fusions and splicing variants is a strong adverse prognostic factor in astrocytoma, isocitrate dehydrogenase mutant	24

Fetal growth restriction adversely impacts trajectory of hippocampal neurodevelopment and function	23
Neuropathological stage‐dependent proteome mapping of the olfactory tract in Alzheimer's disease: From early olfactory‐related omics signatures to computational repurposing of drug candidat	23
Inactivation of the CB₂ receptor accelerated the neuropathological deterioration in TDP‐43 transgenic mice, a model of amyotrophic lateral sclerosis	23
Design and application of a customizable relational DataBase to assess clinicopathological correlations and concomitant pathology in neurodegenerative diseases	22
Protective role of Angiogenin in muscle regeneration in amyotrophic lateral sclerosis: Diagnostic and therapeutic implications	21
Upper motor neuron‐predominant motor neuron disease presenting as atypical parkinsonism: A clinicopathological study	20
Assessment of Ki‐67 and mitoses in pituitary neuroendocrine tumours—Consistency counts	20
Reply to letter by Melmed et al.	20
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Deep learning‐based segmentation in MRI‐(immuno)histological examination of myelin and axonal damage in normal‐appearing white matter and white matter hyperintensities	18
Histamine in murine narcolepsy: What do genetic and immune models tell us?	18
A 7‐year‐old female with hypotonia and scoliosis	18
Issue Information	18
Issue Information	17
Early and extensive alterations of glial connexins, distal oligodendrogliopathy type demyelination, and nodal/paranodal pathology are characteristic of multiple system atrophy	17
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Nicorandil treatment improves survival and spatial learning in aged granulin knockout mice	17
Pathologic TDP‐43 downregulates myelin gene expression in the monkey brain	17
Hypothesis review: Alzheimer's overture guidelines	16
Accumulation of misfolded SOD1 outlines distinct patterns of motor neuron pathology and death during disease progression in a SOD1^G93A mouse model of amyotrophic later	15
A 4‐year‐old boy with a ventricular mass	15
Neuropathological and cerebrospinal fluid correlates of choroid plexus inflammation in progressive multiple sclerosis	15
IDH‐mutant brainstem gliomas in adolescent and young adult patients: Report of three cases and review of the literature	15
Studying the imaging features and infarction mechanism of vertebrobasilar dolichoectasia with high‐resolution magnetic resonance imaging	15
A new amplicon‐based gene panel for next generation sequencing characterization of meningiomas	14
Alpha‐synuclein‐associated changes in PINK1‐PRKN‐mediated mitophagy are disease context dependent	14
Association of CD2AP neuronal deposits with Braak neurofibrillary stage in Alzheimer’s disease	14
Inorganic phosphate exporter heterozygosity in mice leads to brain vascular calcification, microangiopathy, and microgliosis	14
Poly‐GA immunohistochemistry is a reliable tool for detecting C9orf72 hexanucleotide repeat expansions	14
Histopathological patterns in atypical teratoid/rhabdoid tumors are related to molecular subgroup	13
Multiple intracranial hemorrhages in a postmenopausal female	13
Oligodendrocyte progenitor cells' fate after neonatal asphyxia—Puzzling implications for the development of hypoxic–ischemic encephalopathy	13
Postmortem quantitative MRI disentangles histological lesion types in multiple sclerosis	12
Pathological tau signatures and nuclear alterations in neurons, astrocytes and microglia in Alzheimer's disease, progressive supranuclear palsy, and dementia with Lewy bodies	12
Tumor‐associated astrocytes promote tumor progression of Sonic Hedgehog medulloblastoma by secreting lipocalin‐2	12
Distribution of ubiquilin 2 and TDP‐43 aggregates throughout the CNS in UBQLN2 p.T487I‐linked amyotrophic lateral sclerosis and frontotemporal dement	12
Herpes simplex virus‐1 infection alters microtubule‐associated protein Tau splicing and promotes Tau pathology in neural models of Alzheimer's disease	12
Huntingtin CAG repeats in neuropathologically confirmed tauopathies: Novel insights	11
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TDP‐43 and tau concurrence in the entorhinal subfields in primary age‐related tauopathy and preclinical Alzheimer's disease	11
Pathological changes within the cerebral vasculature in Alzheimer’s disease: New perspectives	11
Multiple system atrophy with hippocampal pathology	11
Human amygdala involvement in Alzheimer's disease revealed by stereological and dia‐PASEF analysis	11
Posterior pituitary tumors and other rare entities involving the pituitary gland	11
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Introduction to the mini‐symposium “molecular neuropathology of meningioma”	10
Infective myositis	10
A 57‐year‐old woman with falls, slurred speech, and abnormal MRI signal in the pons, middle cerebellar peduncles, and cerebellum	10
Perivascular phosphorylated TDP‐43 inclusions are associated with Alzheimer's disease pathology and loss of CD146 and Aquaporin‐4	9

Nanoarchitecture of Ca_V2.1 channels and GABA_B receptors in the mouse hippocampus: Impact of APP/PS1 pathology	9
Correction to “A 4‐year‐old boy with a ventricular mass”	9
Lack of classical astroblastoma features in pediatric MN1::BEND2‐fused brain tumors	9
Axonal injury following mild traumatic brain injury is exacerbated by repetitive insult and is linked to the delayed attenuation of NeuN expression without concomitant neuronal death in the mouse	9
Society News	9
Evidence of beta amyloid independent small vessel disease in familial Alzheimer's disease	8
Motor neuron involvement expands the neuropathological phenotype of late‐onset ataxia in RFC1 mutation (CANVAS)	8
An 11‐year‐old boy with a posterior fossa tumor	8
Announcing the Asian Oceanian Society of Neuropathology guidelines for Adapting Diagnostic Approaches for Practical Taxonomy in Resource‐Restrained Regions (AOSNP‐ADAPTR)	8
Altered immune response is associated with sex difference in vulnerability to Alzheimer's disease in human prefrontal cortex	8
Single‐nucleus RNA sequencing unveils critical regulators in various hippocampal neurons for anti‐N‐methyl‐D‐aspartate receptor encephalitis	8
Acknowledgement to Reviewers	8
A 64‐year‐old woman with frontal lobe lesion and drug‐resistant epilepsy	8
Subcortical plaques and inflammation reflect cortical and meningeal pathologies in progressive multiple sclerosis	8
Impact of α‐synuclein spreading on the nigrostriatal dopaminergic pathway depends on the onset of the pathology	8
Progress in stratified stroke characterization—associated with better diagnosis, accurate prognosis and improved treatment strategies	7
Dendritic spine loss in epileptogenic Type II focal cortical dysplasia: Role of enhanced classical complement pathway activation	7
Meeting report of the 20th International Congress of Neuropathology (ICN) 2023 in Berlin	7
Society News	7
Enhanced Creutzfeldt‐Jakob disease surveillance in the older population: Assessment of a protocol for screening brain tissue donations for prion disease	7
Brain‐derived textiloma post glioblastoma resection and application of oxidized regenerated cellulose: A pilot, bedside‐to‐bench, translational study	7
Society News	7
Society News	7
Corrigendum	7
Felice Giangaspero—A man of style and substance	7
Society News	6
Plasma mid‐regional pro‐adrenomedullin: A biomarker of the ischemic penumbra in hyperacute stroke	6
Distribution of ferritin complex in the adult brain and altered composition in neuroferritinopathy due to a novel variant in the ferritin heavy chain gene FTH1 (c.409_410del; p.	6
Diverse changes in microglia morphology and axonal pathology during the course of 1 year after mild traumatic brain injury in pigs	6
A vade mecum for crossing the second translational “valley of death” in brain tumor classification	6
A 76‐year‐old male with multiple enhancing brain lesions	6
RNA‐sequencing highlights differential regulated pathways involved in cell cycle and inflammation in orbitofacial neurofibromas	6
IFNγ protects motor neurons from oxidative stress via enhanced global protein synthesis in FUS‐associated amyotrophic lateral sclerosis	6
Targeting the interaction of GABA_B receptors with CaMKII with an interfering peptide restores receptor expression after cerebral ischemia and inhibits progressive neuronal death in mouse br	6
A 24‐year‐old woman with a recurrent intracranial mass	6
72‐year‐old man with right homonymous hemianopia and gait instability	6
Information theory approaches to improve glioma diagnostic workflows in surgical neuropathology	6
AtypicalTDP‐43 protein expression in anALSpedigree carrying a p.Y374Xtruncation mutation inTARDBP	6
Induced pluripotent stem cell models as a tool to investigate and test fluid biomarkers in Alzheimer's disease and frontotemporal dementia	5
Society News	5
A 55‐year‐old man with a cerebral mass	5
Reduced neurogenesis in human hippocampus with Alzheimer's disease	5
Foxq1 activates CB2R with oleamide to alleviate POCD	5
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A mass in the pineal region of a young woman	5
40‐Year‐old man with two asynchronous spinal cord tumors	5
Dysregulated protein phosphorylation: A determining condition in the continuum of brain aging and Alzheimer's disease	5
Microtubule‐associated NAV3 regulates invasive phenotypes in glioblastoma cells	5
DistSNE: Distributed computing and online visualization of DNA methylation‐based central nervous system tumor classification	5
A supratentorial mass in a young adult, with 25 years of follow‐up	5
Visualizing alpha‐synuclein and iron deposition in M83 mouse model of Parkinson's disease in vivo	5
Spinal intradural pseudocyst formation in central nervous system superficial siderosis	5
The 5th Edition of the WHO Classification of Pituitary Tumors: Strengths and limitations	5
Transmembrane and coiled‐coil 2 associates with Alzheimer's disease pathology in the human brain	5
Molecular profile of adult primary leptomeningeal gliomatosis aligns with glioblastoma, IDH‐wildtype	4
Microglia activation in postmortem brains with schizophrenia demonstrates distinct morphological changes between brain regions	4
Cerebellar structural, astrocytic, and neuronal abnormalities in the SMNΔ7 mouse model of spinal muscular atrophy	4
Independent distribution between tauopathy secondary to subacute sclerotic panencephalitis and measles virus: An immunohistochemical analysis in autopsy cases including cases treated with aggressive a	4
Present and future avenues of cell‐based therapy for brain injury: The enteric nervous system as a potential cell source	4
Molecular landscapes of longitudinal NF2/22q and non‐NF2/22q meningiomas show different life histories	4
Issue Information	4
Glutamatergic receptor expression changes in the Alzheimer's disease hippocampus and entorhinal cortex	4
Molecular neuropathology of brain‐invasive meningiomas	4
Transient receptor potential vanilloid 1 inhibition reduces brain damage by suppressing neuronal apoptosis after intracerebral hemorrhage	3
The role of interferons type I, II and III in myositis: A review	3
Altered properties of amyloidogenic prion protein in genetic Creutzfeldt–Jakob disease with PRNP V180I mutation in response to pentosan polysulfate	3
LATE‐NC in Alzheimer's disease: Molecular aspects and synergies	3
41‐year‐old male with a pituitary mass	3
The pontine diffuse midline glioma, EGFR‐subtype with ependymal features: Yet another face of diffuse midline glioma, H3K27‐altered	3
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Novel genetic variants in MAPT and alterations in tau phosphorylation in amyotrophic lateral sclerosis post‐mortem motor cortex and cerebrospinal fluid	3
Ermin deficiency leads to compromised myelin, inflammatory milieu, and susceptibility to demyelinating insult	3
Acknowledgement to Reviewers	3
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Proteomic analysis of human hippocampal subfields provides new insights into the pathogenesis of Alzheimer’s disease and the role of glial cells	3
The 2021 WHO Classification of Tumors of the Central Nervous System: An update on pediatric low‐grade gliomas and glioneuronal tumors	3
A 58‐year‐old man with B‐cell chronic lymphocytic leukemia and multiple strokes	3
Three‐year‐old with severe‐combined immunodeficiency and a mildly expansile T2/FLAIR signal abnormality	3
Issue Information	2

Society News	2
Issue Information	2
Embryonal and non‐meningothelial mesenchymal tumors of the central nervous system – Advances in diagnosis and prognostication	2
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A 7‐month‐old boy with failure to thrive	2
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A 7‐year‐old boy presented with temporal lobe lesion	2
A 31‐year‐old man with recurrent blurred vision	2
Contribution of whole slide imaging‐based deep learning in the assessment of intraoperative and postoperative sections in neuropathology	2
Ranking and filtering of neuropathology features in the machine learning evaluation of dementia studies	2
Society News	2
Role of VAPB and vesicular profiles in α‐synuclein aggregates in multiple system atrophy	2
Astrocytes for brain repair: More than just a neuron’s sidekick	2
Issue Information	2
Degeneration of olivospinal tract in the upper cervical spinal cord of multiple system atrophy patients: Reappraisal of Helweg's triangular tract	2
Brain heterotopia formation by ciliopathic breakdown of neuroepithelial and blood‐cerebrospinal fluid barriers	2
A 53‐year‐old woman with a rapidly progressive, non‐enhancing left frontotemporal lesion	2
Issue Information	2
Serotonin transporter in the temporal lobe, hippocampus and amygdala in SUDEP	2
Issue Information	2
Author Index	2
Issue Information	2
Special Issue: Abstracts of the 20^th International Congress of Neuropathology, Berlin, Germany, September 13–16, 2023	1
Sterol imbalances and cholesterol‐24‐hydroxylase dysregulation is linked to the underlying progression of multiple sclerosis	1
Potentiating microglial efferocytosis by MFG‐E8 improves survival and neurological outcome after successful cardiopulmonary resuscitation in mice	1
Report two adult cases of high‐grade neuroepithelial neoplasm harbouring EP300::BCOR fusions with comprehensive molecular detection	1
A 2‐year‐old girl with posterior fossa mass	1
Evaluating the performance of large language models: ChatGPT and Google Bard in generating differential diagnoses in clinicopathological conferences of neurodegenerative disorders	1
No evidence of aberrant amyloid β and phosphorylated tau expression in herpes simplex virus‐infected neurons of the trigeminal ganglia and brain	1
Effect of olfactory bulb pathology on olfactory function in normal aging	1
Hispano‐American Brain Bank on Neurodevelopmental Disorders: An initiative to promote brain banking, research, education, and outreach in the field of neurodevelopmental disorders	1
The prevalence of chronic traumatic encephalopathy in a historical epilepsy post‐mortem collection	1
Issue Information	1
Grading and staging for pituitary neuroendocrine tumors	1
Krüppel‐like factor 7 deficiency disrupts corpus callosum development and neuronal migration in the developing mouse cerebral cortex	1
Mitochondrial DNA variants in inclusion body myositis characterized by deep sequencing	1
Astrocytic phagocytosis in the medial prefrontal cortex jeopardises postoperative memory consolidation in mice	1
The neurovasculature as a target in temporal lobe epilepsy	1
Generation of new transgenic SMARCA4‐deficient mouse models results in neuromuscular weakness and paralysis of limbs	1
Alleviating early demyelination in ischaemia/reperfusion by inhibiting sphingosine‐1‐phosphate receptor 2 could protect visual function from impairment	1
Proteomic analysis identifies HSP90AA1, PTK2B, and ANXA2 in the human entorhinal cortex in Alzheimer's disease: Potential role in synaptic homeos	1
An integrative histopathological and epigenetic characterization of primary intracranial mesenchymal tumors, FET:CREB‐fused broadening the spectrum of tumor entities in comparison with their soft tiss	1
Resource availability for CNS tumor diagnostics in the Asian Oceanian region: A survey by the Asian Oceanian Society of Neuropathology committee for Adapting Diagnostic Approaches for Pract	1
Application of single cell genomics to focal epilepsies: A call to action	1
Aerobic exercise improves astrocyte mitochondrial quality and transfer to neurons in a mouse model of Alzheimer's disease	1
Society News	1
Microvessel stenosis, enlarged perivascular spaces, and fibrinogen deposition are associated with ischemic periventricular white matter hyperintensities	1
Intraventricular mass in a 52‐year‐old woman	1
Reduction in miR‐219 expression underlies cellular pathogenesis of oligodendrocytes in a mouse model of Krabbe disease	1
hnRNP A1, hnRNP A2B1, and hnRNP K are dysregulated in tauopathies, but do not colocalize with tau pathology	1
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TREM2‐induced activation of microglia contributes to synaptic integrity in cognitively intact aged individuals with Alzheimer's neuropathology	1
Cortical iron accumulation in MAPT‐ and C9orf 72‐associated frontotemporal lobar degeneration	1
Validation of target‐enriched enzymatic methylation sequencing for brain tumor classification from formalin‐fixed paraffin embedded‐derived DNA	1
Epilepsy‐associated death in the Southwestern Ontario: A clinicopathological correlation study	1
Prognostic impact of genetic alterations and methylation classes in meningioma	1
Does etiology really matter for epilepsy surgery outcome?	1
Fra‐1 induces apoptosis and neuroinflammation by targeting S100A8 to modulate TLR4 pathways in spinal cord ischemia/reperfusion injury	1