Brain Pathology

Article	Citations
	175
Issue Information	127
Herpes simplex virus‐1 infection alters microtubule‐associated protein Tau splicing and promotes Tau pathology in neural models of Alzheimer's disease	100
A 29‐year‐old man with a right intracranial mass	86
Reply to letter by Melmed et al.	64
Issue Information	62
Left dural‐based mass in a 62‐year‐old female	54
Issue Information	47
Accumulation of misfolded SOD1 outlines distinct patterns of motor neuron pathology and death during disease progression in a SOD1G93A mouse model of amyotrophic later	42
Astrocyte‐derived Interleukin‐31 causes poor prognosis in elderly patients with intracerebral hemorrhage	40
Pathologic TDP‐43 downregulates myelin gene expression in the monkey brain	38
Intraventricular mass in a 49‐year‐old male	35
	35
Dysregulation of the endosomal sorting complex III is linked to neurodegeneration in progressive multiple sclerosis	33
Human amygdala involvement in Alzheimer's disease revealed by stereological and dia‐PASEF analysis	32
Neuropathological and cerebrospinal fluid correlates of choroid plexus inflammation in progressive multiple sclerosis	31
Tumor‐associated astrocytes promote tumor progression of Sonic Hedgehog medulloblastoma by secreting lipocalin‐2	30
	29
Issue Information	27
A 76‐year‐old male with multiple enhancing brain lesions	27
Molecular profile of adult primary leptomeningeal gliomatosis aligns with glioblastoma, IDH‐wildtype	26
A 55‐year‐old man with a cerebral mass	26
Progress in stratified stroke characterization—associated with better diagnosis, accurate prognosis and improved treatment strategies	26
40‐Year‐old man with two asynchronous spinal cord tumors	24
Alzheimer's disease and mixed pathologies as a hidden contributor to fatal hypothermia: A large‐scale forensic autopsy‐based study	23

Cerebellar structural, astrocytic, and neuronal abnormalities in the SMNΔ7 mouse model of spinal muscular atrophy	23
Dendritic location of dystrophic neurites in FTLD ‐ TDP type C with annexinopathy	22
Molecular neuropathology of brain‐invasive meningiomas	21
The physiological and pathological effects of sphingolipid metabolism and signaling in the central nervous system	21
Visualizing alpha‐synuclein and iron deposition in M83 mouse model of Parkinson's disease in vivo	20
Epilepsy‐associated death in the Southwestern Ontario: A clinicopathological correlation study	20
The pontine diffuse midline glioma, EGFR‐subtype with ependymal features: Yet another face of diffuse midline glioma, H3K27‐altered	19
Issue Information	19
A posterior fossa mass in a 4‐year‐old female	19
Evaluating the performance of large language models: ChatGPT and Google Bard in generating differential diagnoses in clinicopathological conferences of neurodegenerative disorders	18
Prognostic impact of genetic alterations and methylation classes in meningioma	18
Embryonal and non‐meningothelial mesenchymal tumors of the central nervous system – Advances in diagnosis and prognostication	17
Potentiating microglial efferocytosis by MFG‐E8 improves survival and neurological outcome after successful cardiopulmonary resuscitation in mice	17
	17
Issue Information	16
	16
Selective neurodegeneration generated by intravenous α‐synuclein pre‐formed fibril administration is not associated with endogenous α‐synuclein levels in the rat brain	16
Clinico‐sero‐pathological characteristics of anti‐Ha antisynthetase syndrome	15
	15
Refinement of prognostication for IDH‐mutant astrocytomas using DNA methylation‐based classification	15
Genomic profiling and prognostic factors of H3 K27M‐mutant spinal cord diffuse glioma	15
Neurofilament light chain as a marker of peripheral nerve damage in vasculitic neuropathy? A cross‐compartmental correlation analysis in patients undergoing nerve biopsy	15
Issue Information	14
The relation between BTK expression and iron accumulation of myeloid cells in multiple sclerosis	14
Colocalization of TDP‐43 and stress granules at the early stage of TDP‐43 aggregation in amyotrophic lateral sclerosis	14
Issue Information	14
SOCIETY NEWS	14
Society News	14
Muscle pathology of antisynthetase syndrome according to antibody subtypes	13
Primary visual cortex pathology in ALS patients with C9ORF72 expansion	13
Alpha‐synuclein fibrils amplified from multiple system atrophy and Parkinson's disease patient brain spread after intracerebral injection into mouse brain	13
Issue Information	13
	13
LAMP‐2A ablation in hippocampal CA1 astrocytes confers cerebroprotection and ameliorates neuronal injury after global brain ischemia	13
NAB2::STAT6 fusions and genome‐wide DNA methylation profiling: Predictors of patient outcomes in meningeal solitary fibrous tumors	13
A role for vessel‐associated extracellular matrix proteins in multiple sclerosis pathology	12
Paul Kleihues (1936–2022), neuropathology innovator and entrepreneur	12
Human amyotrophic lateral sclerosis/motor neuron disease: The disease‐associated microglial pathway is upregulated while APOE genotype governs risk and survival	12
Did early studies of human traumatic brain injury overlook concomitant oligodendrocyte pathology in injured white matter tracts? A comment on “Detection and verification of neurodegeneration after tra	12
Upregulation of sphingomyelin and ABCA8 in response to TDP ‐43 pathology in amyotrophic lateral sc	12
Molecular landscape of IDH‐wild type, pTERT‐wild type adult glioblastomas	11
Dysregulation of the renin‐angiotensin system in vascular dementia	11
Multiple intracranial hemorrhages in a postmenopausal female	11
Mic60 is essential to maintain mitochondrial integrity and to prevent encephalomyopathy	11
Differential perivascular microglial activation in the deep white matter in vascular dementia developed post‐stroke	11
Brain‐specific loss of Abcg1 disturbs cholesterol metabolism and aggravates pyroptosis and neurological deficits after traumatic brain injury	11
Clinicopathological analysis of NEK1 variants in amyotrophic lateral sclerosis	11
Monomeric C‐reactive protein: A novel biomarker predicting neurodegenerative disease and vascular dysfunction	11
A 4‐year‐old boy with a ventricular mass	10
Issue Information	10

Inorganic phosphate exporter heterozygosity in mice leads to brain vascular calcification, microangiopathy, and microgliosis	10
Poly‐GA immunohistochemistry is a reliable tool for detecting C9orf72 hexanucleotide repeat expansions	10
	10
Postmortem quantitative MRI disentangles histological lesion types in multiple sclerosis	10
Nitro‐oleic acid activation of endothelial PPARγ signaling pathway alleviates neurovascular injury and improves functional outcomes in ischemic strok	10
Early and extensive alterations of glial connexins, distal oligodendrogliopathy type demyelination, and nodal/paranodal pathology are characteristic of multiple system atrophy	10
Issue Information	10
A 24‐year‐old woman with a recurrent intracranial mass	9
Dendritic spine loss in epileptogenic Type II focal cortical dysplasia: Role of enhanced classical complement pathway activation	9
Distribution of ferritin complex in the adult brain and altered composition in neuroferritinopathy due to a novel variant in the ferritin heavy chain gene FTH1 (c.409_410del; p.	9
A vade mecum for crossing the second translational “valley of death” in brain tumor classification	9
Deep learning‐based segmentation in MRI‐(immuno)histological examination of myelin and axonal damage in normal‐appearing white matter and white matter hyperintensities	9
Foxq1 activates CB2R with oleamide to alleviate POCD	8
Reduced neurogenesis in human hippocampus with Alzheimer's disease	8
Targeting the interaction of GABAB receptors with CaMKII with an interfering peptide restores receptor expression after cerebral ischemia and inhibits progressive neuronal death in mouse br	8
An 11‐year‐old boy with a posterior fossa tumor	8
LATE‐NC in Alzheimer's disease: Molecular aspects and synergies	8
Independent distribution between tauopathy secondary to subacute sclerotic panencephalitis and measles virus: An immunohistochemical analysis in autopsy cases including cases treated with aggressive a	8
Single‐nucleus RNA sequencing unveils critical regulators in various hippocampal neurons for anti‐N‐methyl‐D‐aspartate receptor encephalitis	8
Ranking and filtering of neuropathology features in the machine learning evaluation of dementia studies	7
Microglial reactivity and nodule formation are associated with Synaptodendritic damage in the brains of people with HIV ‐1	7
Understanding the pathogenic mechanisms and therapeutic effects in neurocysticercosis	7
Cortical iron accumulation in MAPT‐ and C9orf 72‐associated frontotemporal lobar degeneration	7
Hippo pathway effectors are associated with glioma patient survival, control cell proliferation and sterol metabolism through TEAD3	7
	7
A 31‐year‐old man with recurrent blurred vision	7
cIMPACT ‐ NOW update 11: Proposal on adaptation of diagnostic criteria for IDH	7
Serotonin transporter in the temporal lobe, hippocampus and amygdala in SUDEP	7
Differential expression of checkpoint markers in the normoxic and hypoxic microenvironment of glioblastomas	6
Society News	6
Neuropathological hallmarks in autopsied cases with mitochondrial diseases caused by the mitochondrial 3243A>G mutation	6
Targeting TRPV4 to restore glymphatic system function and alleviate cerebral edema in ischemic stroke	6
Issue Information	6
Society News	6
	6
Concomitant progressive supranuclear palsy and Lewy body pathology presenting with circumscribed visual memory loss: A clinicopathological case	6
	6
Dynamic induction of the myelin‐associated growth inhibitor Nogo‐A in perilesional plasticity regions after human spinal cord injury	6
Quantitative magnetic resonance imaging reflects different levels of histologically determined myelin densities in multiple sclerosis, including remyelination in inactive multiple sclerosis lesions	6
CHCHD2 p.Thr61Ile knock‐in mice exhibit motor defects and neuropathological features of Parkinson's disease	6
Evidence of emerging transcriptome mediators of Alzheimer's disease in canine cognitive dysfunction	6
A 16‐year‐old female with an intrasellar mass	5
Inflammatory and oxidative stress markers in intracerebral hemorrhage: Relevance as prognostic markers for quantification of the edema volume	5
Morphology‐based molecular classification of spinal cord ependymomas using deep neural networks	5
Identification of a distinct epigenetic subgroup with inferior PFS in intracranial mesenchymal tumors with FET::CREB fusion	5
A comprehensive histomolecular characterization of meningioangiomatosis: Further evidence for a precursor neoplastic lesion	5
Increased expression of human antiviral protein MxA in FUS proteinopathy in amyotrophic lateral sclerosis	5
Friends or foes: The mononuclear phagocyte system in ischemic stroke	5
Correction to “Brain alpha‐amylase: A novel energy regulator important in Alzheimer disease?”	5
Alzheimer's disease phenotype based upon the carrier status of the apolipoprotein E ɛ4 allele	5
The WHO classification of tumors of the central nervous system‐finally here, and welcome!	5
A 3‐year‐old male with an extramedullary, intra‐ and extradural mass at T11‐L1	5
Automated analysis of gray matter damage in aged mice reveals impaired remyelination in the cuprizone model	5
Tau‐targeting active immunotherapy slows progression and reduces pathology in mouse models of tauopathy	5
The fate of interneurons, GABAA receptor sub‐types and perineuronal nets in Alzheimer's disease	5
Gliovascular alterations in sporadic and familial Alzheimer's disease: APOE3 Christchurch homozygote glioprotection	5
A 63‐year‐old woman with parietal scalp surface rugged	5
	4
The association between neurodegeneration and local complement activation in the thalamus to progressive multiple sclerosis outcome	4
Neuropathological stage‐dependent proteome mapping of the olfactory tract in Alzheimer's disease: From early olfactory‐related omics signatures to computational repurposing of drug candidat	4
Society News	4
A tribute to John Q. Trojanowski (1946–2022), neuropathologist extraordinaire	4
Design and application of a customizable relational DataBase to assess clinicopathological correlations and concomitant pathology in neurodegenerative diseases	4
The post‐stroke young adult brain has limited capacity to re‐express the gene expression patterns seen during early postnatal brain development	4
Somatostatin receptors in pituitary somatotroph adenomas as predictors of response to somatostatin receptor ligands: A pathologist's perspective	4
Exploiting nanopore sequencing for characterization and grading of IDH‐mutant gliomas	4
Multi‐pronged analysis of pediatric low‐grade glioma and ganglioglioma reveals a unique tumor microenvironment associated with BRAF alterations	4
A new amplicon‐based gene panel for next generation sequencing characterization of meningiomas	4
Information theory approaches to improve glioma diagnostic workflows in surgical neuropathology	3
TDP‐43 and tau concurrence in the entorhinal subfields in primary age‐related tauopathy and preclinical Alzheimer's disease	3
A young man with multifocal brainstem leptomeningeal disease	3
Nanoarchitecture of CaV2.1 channels and GABAB receptors in the mouse hippocampus: Impact of APP/PS1 pathology	3
Author Index	3
Enhanced Creutzfeldt‐Jakob disease surveillance in the older population: Assessment of a protocol for screening brain tissue donations for prion disease	3
Pathological tau signatures and nuclear alterations in neurons, astrocytes and microglia in Alzheimer's disease, progressive supranuclear palsy, and dementia with Lewy bodies	3
Hypothesis review: Alzheimer's overture guidelines	3
Society News	3
IFNγ protects motor neurons from oxidative stress via enhanced global protein synthesis in FUS ‐associated amyotrophic	3
Brain heterotopia formation by ciliopathic breakdown of neuroepithelial and blood‐cerebrospinal fluid barriers	3
The 2021 WHO Classification of Tumors of the Central Nervous System: An update on pediatric low‐grade gliomas and glioneuronal tumors	3

Studying the imaging features and infarction mechanism of vertebrobasilar dolichoectasia with high‐resolution magnetic resonance imaging	3
	3
Present and future avenues of cell‐based therapy for brain injury: The enteric nervous system as a potential cell source	3
	3
Acknowledgement to Reviewers	3
Issue Information	3
Developmental delay and progressive seizures in 2‐month‐old child with diffuse MRI abnormalities	2
	2
Extralysosomal cathepsin B in central nervous system: Mechanisms and therapeutic implications	2
Aβ plaques do not protect against HSV‐1 infection in a mouse model of familial Alzheimer's disease, and HSV‐1 does not induce Aβ pathology in a model of late onset Alzheimer's di	2
Extra‐axial mass in a 72‐year‐old woman	2
Society News	2
Proteomic analysis identifies HSP90AA1, PTK2B, and ANXA2 in the human entorhinal cortex in Alzheimer's disease: Potential role in synaptic homeos	2
	2
	2
A 53‐year‐old woman with a 16‐year history of epilepsy	2
Stereological analysis of cholinergic neurons within bilateral pedunculopontine nuclei in health and when affected by Parkinson's disease	2
The molecular history of IDH‐mutant astrocytomas without adjuvant treatment	2
Two novel tumours with NTRK2 fusion in the methylation class of extraventricular neurocytomas, including one intraventricular	2
Attenuation of Piwil2 induced by hypoxic postconditioning prevents cerebral ischemic injury by inhibiting CREB2 promoter methylation	2
Krüppel‐like factor 7 deficiency disrupts corpus callosum development and neuronal migration in the developing mouse cerebral cortex	2
Recurrent TRAK1::RAF1 Fusions in pediatric low‐grade gliomas	2
Correspondence to: Clinico‐sero‐pathological characteristics of anti‐Ha antisynthetase syndrome	2
Detection and verification of neurodegeneration after traumatic brain injury in the mouse: Immunohistochemical staining for amyloid precursor protein	2
Decreased microvascular claudin‐5 levels in cerebral amyloid angiopathy associated with intracerebral haemorrhage	2
Pathology explains various mechanisms of auto‐immune inflammatory peripheral neuropathies	2
Report two adult cases of high‐grade neuroepithelial neoplasm harbouring EP300::BCOR fusions with comprehensive molecular detection	2
A 7‐year‐old boy presented with temporal lobe lesion	2
	2
Temporal lobe myxoid glioneuronal tumor, PDGFRA p.K385L‐mutant with DNA methylation confirmation	2
The prevalence of chronic traumatic encephalopathy in a historical epilepsy post‐mortem collection	1
Felice Giangaspero—A man of style and substance	1
AtypicalTDP‐43 protein expression in anALSpedigree carrying a p.Y374Xtruncation mutation inTARDBP	1
A supratentorial mass in a young adult, with 25 years of follow‐up	1
MET fusions and splicing variants is a strong adverse prognostic factor in astrocytoma, isocitrate dehydrogenase mutant	1
A 7‐year‐old female with hypotonia and scoliosis	1
Endoplasmic reticulum‐stress and unfolded protein response‐activation in immune‐mediated necrotizing myopathy	1
Age‐related hearing loss and dementia‐related neuropathology: An analysis of the United Kingdom brains for dementia research cohort	1
Meeting report of the 20th International Congress of Neuropathology (ICN) 2023 in Berlin	1
Contribution of whole slide imaging‐based deep learning in the assessment of intraoperative and postoperative sections in neuropathology	1
Society News	1
Issue Information	1
Calponin‐3 is associated with epilepsy through the regulation of astrocyte activity	1
Introduction to the mini‐symposium “molecular neuropathology of meningioma”	1
cIMPACT‐NOW update 10: Recommendations for defining new types for central nervous system tumor classification	1
Multiple system atrophy with hippocampal pathology	1
Nicorandil treatment improves survival and spatial learning in aged granulin knockout mice	1
Vascular endothelial growth factor‐C modulates cortical NMDA receptor activity in cortical lesions of young patients and rat model with focal cortical dysplasia	1
A mass in the pineal region of a young woman	1
Dysmorphic neurons express markers of inhibitory glycinergic signaling in focal cortical dysplasia IIb	1
Sterol imbalances and cholesterol‐24‐hydroxylase dysregulation is linked to the underlying progression of multiple sclerosis	1
Issue Information	1
Effect of olfactory bulb pathology on olfactory function in normal aging	1
Correction to “A 4‐year‐old boy with a ventricular mass”	1
Perivascular phosphorylated TDP‐43 inclusions are associated with Alzheimer's disease pathology and loss of CD146 and Aquaporin‐4	1
Variable histopathology features of neuronal dyslamination in the cerebral neocortex adjacent to epilepsy‐associated vascular malformations suggest complex pathogenesis of focal cortical dysplasia ILA	1
Comparative pathology boards facilitate the translation of knowledge between canine and human cancer patients	1
Updates in the classification of ependymal neoplasms: The 2021 WHO Classification and beyond	1
Functionally distinct pericyte subsets differently regulate amyloid‐β deposition in patients with Alzheimer's disease	1
A diffuse glioma with oligodendroglial‐like cells and extensive calcifications	1
Society News	1