OOIR: Observatory of International Research

Papers

(The TQCC of Brain Pathology is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)

Article	Citations
	75
Issue Information	70
Reply to letter by Melmed et al.	47
A 29‐year‐old man with a right intracranial mass	47
Issue Information	44
Left dural‐based mass in a 62‐year‐old female	43
Issue Information	42
Intraventricular mass in a 49‐year‐old male	40
	40
Dysregulation of the endosomal sorting complex III is linked to neurodegeneration in progressive multiple sclerosis	40
Neuropathological and cerebrospinal fluid correlates of choroid plexus inflammation in progressive multiple sclerosis	35
Pathologic TDP‐43 downregulates myelin gene expression in the monkey brain	35
Astrocyte‐derived Interleukin‐31 causes poor prognosis in elderly patients with intracerebral hemorrhage	34
Herpes simplex virus‐1 infection alters microtubule‐associated protein Tau splicing and promotes Tau pathology in neural models of Alzheimer's disease	31
Human amygdala involvement in Alzheimer's disease revealed by stereological and dia‐PASEF analysis	30
Tumor‐associated astrocytes promote tumor progression of Sonic Hedgehog medulloblastoma by secreting lipocalin‐2	28
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Dendritic location of dystrophic neurites in FTLD ‐ TDP type C with annexinopathy	25
Issue Information	25
Alzheimer's disease and mixed pathologies as a hidden contributor to fatal hypothermia: A large‐scale forensic autopsy‐based study	24
40‐Year‐old man with two asynchronous spinal cord tumors	21
Molecular profile of adult primary leptomeningeal gliomatosis aligns with glioblastoma, IDH‐wildtype	21
Visualizing alpha‐synuclein and iron deposition in M83 mouse model of Parkinson's disease in vivo	20
A 55‐year‐old man with a cerebral mass	20
Progress in stratified stroke characterization—associated with better diagnosis, accurate prognosis and improved treatment strategies	20

Cerebellar structural, astrocytic, and neuronal abnormalities in the SMNΔ7 mouse model of spinal muscular atrophy	19
Issue Information	19
The physiological and pathological effects of sphingolipid metabolism and signaling in the central nervous system	19
Epilepsy‐associated death in the Southwestern Ontario: A clinicopathological correlation study	18
A posterior fossa mass in a 4‐year‐old female	18
Potentiating microglial efferocytosis by MFG‐E8 improves survival and neurological outcome after successful cardiopulmonary resuscitation in mice	18
Human brain matters: Navigating the neuropathology of COVID ‐19	17
The pontine diffuse midline glioma, EGFR‐subtype with ependymal features: Yet another face of diffuse midline glioma, H3K27‐altered	17
	17
A 17‐year‐old male with chronic epilepsy status post remote functional hemispherectomy	17
Evaluating the performance of large language models: ChatGPT and Google Bard in generating differential diagnoses in clinicopathological conferences of neurodegenerative disorders	17
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Issue Information	16
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Issue Information	15
Genomic profiling and prognostic factors of H3 K27M‐mutant spinal cord diffuse glioma	15
Clinico‐sero‐pathological characteristics of anti‐Ha antisynthetase syndrome	15
Colocalization of TDP‐43 and stress granules at the early stage of TDP‐43 aggregation in amyotrophic lateral sclerosis	15
Neurofilament light chain as a marker of peripheral nerve damage in vasculitic neuropathy? A cross‐compartmental correlation analysis in patients undergoing nerve biopsy	15
SOCIETY NEWS	15
Refinement of prognostication for IDH‐mutant astrocytomas using DNA methylation‐based classification	15
Selective neurodegeneration generated by intravenous α‐synuclein pre‐formed fibril administration is not associated with endogenous α‐synuclein levels in the rat brain	15
Issue Information	14
Primary visual cortex pathology in ALS patients with C9ORF72 expansion	14
Issue Information	14
Did early studies of human traumatic brain injury overlook concomitant oligodendrocyte pathology in injured white matter tracts? A comment on “Detection and verification of neurodegeneration after tra	13
The relation between BTK expression and iron accumulation of myeloid cells in multiple sclerosis	13
Alpha‐synuclein fibrils amplified from multiple system atrophy and Parkinson's disease patient brain spread after intracerebral injection into mouse brain	13
Brain‐specific loss of Abcg1 disturbs cholesterol metabolism and aggravates pyroptosis and neurological deficits after traumatic brain injury	13
NAB2::STAT6 fusions and genome‐wide DNA methylation profiling: Predictors of patient outcomes in meningeal solitary fibrous tumors	13
Muscle pathology of antisynthetase syndrome according to antibody subtypes	13
	13
LAMP‐2A ablation in hippocampal CA1 astrocytes confers cerebroprotection and ameliorates neuronal injury after global brain ischemia	13
Upregulation of sphingomyelin and ABCA8 in response to TDP ‐43 pathology in amyotrophic lateral sc	12
Molecular landscape of IDH‐wild type, pTERT‐wild type adult glioblastomas	12
Clinicopathological analysis of NEK1 variants in amyotrophic lateral sclerosis	12
A role for vessel‐associated extracellular matrix proteins in multiple sclerosis pathology	12
Mic60 is essential to maintain mitochondrial integrity and to prevent encephalomyopathy	12
Dysregulation of the renin‐angiotensin system in vascular dementia	12
Human amyotrophic lateral sclerosis/motor neuron disease: The disease‐associated microglial pathway is upregulated while APOE genotype governs risk and survival	11
Differential perivascular microglial activation in the deep white matter in vascular dementia developed post‐stroke	11
Monomeric C‐reactive protein: A novel biomarker predicting neurodegenerative disease and vascular dysfunction	11
	10
A 4‐year‐old boy with a ventricular mass	10
Postmortem quantitative MRI disentangles histological lesion types in multiple sclerosis	10
Issue Information	10
Deep learning‐based segmentation in MRI‐(immuno)histological examination of myelin and axonal damage in normal‐appearing white matter and white matter hyperintensities	10
Inorganic phosphate exporter heterozygosity in mice leads to brain vascular calcification, microangiopathy, and microgliosis	10
Early and extensive alterations of glial connexins, distal oligodendrogliopathy type demyelination, and nodal/paranodal pathology are characteristic of multiple system atrophy	10
Multiple intracranial hemorrhages in a postmenopausal female	10

Issue Information	10
Poly‐GA immunohistochemistry is a reliable tool for detecting C9orf72 hexanucleotide repeat expansions	10
Foxq1 activates CB2R with oleamide to alleviate POCD	9
A vade mecum for crossing the second translational “valley of death” in brain tumor classification	9
Targeting the interaction of GABA_B receptors with CaMKII with an interfering peptide restores receptor expression after cerebral ischemia and inhibits progressive neuronal death in mouse br	9
An 11‐year‐old boy with a posterior fossa tumor	9
Microglial reactivity and nodule formation are associated with Synaptodendritic damage in the brains of people with HIV ‐1	9
Dendritic spine loss in epileptogenic Type II focal cortical dysplasia: Role of enhanced classical complement pathway activation	9
Brain viral reservoir seeding and neurological metabolic dysregulation in early‐life immunodeficiency virus infection	9
Nitro‐oleic acid activation of endothelial PPARγ signaling pathway alleviates neurovascular injury and improves functional outcomes in ischemic strok	9
A 24‐year‐old woman with a recurrent intracranial mass	9
Distribution of ferritin complex in the adult brain and altered composition in neuroferritinopathy due to a novel variant in the ferritin heavy chain gene FTH1 (c.409_410del; p.	9
Reduced neurogenesis in human hippocampus with Alzheimer's disease	9
Cortical iron accumulation in MAPT‐ and C9orf 72‐associated frontotemporal lobar degeneration	8
Ranking and filtering of neuropathology features in the machine learning evaluation of dementia studies	8
Single‐nucleus RNA sequencing unveils critical regulators in various hippocampal neurons for anti‐N‐methyl‐D‐aspartate receptor encephalitis	8
A 31‐year‐old man with recurrent blurred vision	8
LATE‐NC in Alzheimer's disease: Molecular aspects and synergies	8
	7
Associations between TMEM106B C‐terminal fragment aggregation, age, and TDP ‐43 or tau pathology	7
Patient‐derived surgical samples reveal the cellular and molecular signatures of glioblastoma infiltration in distinct radiological zones	7
cIMPACT ‐ NOW update 11: Proposal on adaptation of diagnostic criteria for IDH	7
	7
Hippo pathway effectors are associated with glioma patient survival, control cell proliferation and sterol metabolism through TEAD3	7
CRYAB is compromised in pathologically affected oligodendrocytes in multiple system atrophy	7
Understanding the pathogenic mechanisms and therapeutic effects in neurocysticercosis	7
Clinical and molecular features of primary gliosarcoma with digital spatial whole‐transcriptome analysis of glial and mesenchymal components	7