OOIR: Observatory of International Research

Papers

(The TQCC of Brain Pathology is 10. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-05-01 to 2024-05-01.)

Article	Citations
cIMPACT‐NOW update 7: advancing the molecular classification of ependymal tumors	164
Neuropathologic features of four autopsied COVID‐19 patients	146
The 2021 WHO Classification of Tumors of the Central Nervous System: An update on pediatric low‐grade gliomas and glioneuronal tumors	78
COVID‐19‐related neuropathology and microglial activation in elderly with and without dementia	76
SARS‐CoV‐2 and the brain: A review of the current knowledge on neuropathology in COVID‐19	75
Pathology, diagnostics, and classification of medulloblastoma	72
Loss of capillary pericytes and the blood–brain barrier in white matter in poststroke and vascular dementias and Alzheimer’s disease	62
Classification of adult‐type diffuse gliomas: Impact of the World Health Organization 2021 update	57
Brain ischemic injury in COVID‐19‐infected patients: a series of 10 post‐mortem cases	56
The microbiota–microglia axis in central nervous system disorders	55
The role of interferons type I, II and III in myositis: A review	47
Microglia activation in postmortem brains with schizophrenia demonstrates distinct morphological changes between brain regions	47
Intracranial mesenchymal tumor with FET‐CREB fusion—A unifying diagnosis for the spectrum of intracranial myxoid mesenchymal tumors and angiomatoid fibrous histiocytoma‐like neoplasms	42
Mediators of cerebral hypoperfusion and blood‐brain barrier leakiness in Alzheimer’s disease, vascular dementia and mixed dementia	41
Chronic sleep deprivation altered the expression of circadian clock genes and aggravated Alzheimer's disease neuropathology	39
Evolution of neuronal and glial tau isoforms in chronic traumatic encephalopathy	39
IL‐1β/IL‐1R1 signaling induced by intranasal lipopolysaccharide infusion regulates alpha‐Synuclein pathology in the olfactory bulb, substantia nigra and striatum	39
Accumulation of neurofibrillary tangles and activated microglia is associated with lower neuron densities in the aphasic variant of Alzheimer’s disease	36
Updates in the classification of ependymal neoplasms: The 2021 WHO Classification and beyond	32
Dysregulated protein phosphorylation: A determining condition in the continuum of brain aging and Alzheimer's disease	32
The spectrum of rare central nervous system (CNS) tumors with EWSR1‐non‐ETS fusions: experience from three pediatric institutions with review of the literature	32
Interaction of microglia with infiltrating immune cells in the different phases of stroke	32
Pathological changes within the cerebral vasculature in Alzheimer’s disease: New perspectives	31
Tumor cell and immune cell profiles in primary human glioblastoma: Impact on patient outcome	30
MRI and muscle imaging for idiopathic inflammatory myopathies	30

Prognostic impact of genetic alterations and methylation classes in meningioma	29
Biology and grading of pleomorphic xanthoastrocytoma—what have we learned about it?	29
TERT promoter mutations in primary and secondary WHO grade III meningioma	29
Genomic mechanisms in Alzheimer's disease	29
Glycocalyx is critical for blood‐brain barrier integrity by suppressing caveolin1‐dependent endothelial transcytosis following ischemic stroke	28
Limbic‐predominant age‐related TDP‐43 encephalopathy neuropathologic change and microvascular pathologies in community‐dwelling older persons	26
Infective myositis	25
Distinct changes in all major components of the neurovascular unit across different neuropathological stages of Alzheimer's disease	24
Postmortem neuropathology in COVID‐19	24
Glutamatergic receptor expression changes in the Alzheimer's disease hippocampus and entorhinal cortex	24
Toward a refined genotype–phenotype classification scheme for the international consensus classification of Focal Cortical Dysplasia	24
Detection and quantification of novel C‐terminal TDP‐43 fragments in ALS‐TDP	23
Role of mTOR‐regulated autophagy in spine pruning defects and memory impairments induced by binge‐like ethanol treatment in adolescent mice	23
Increased expression of miR142 and miR155 in glial and immune cells after traumatic brain injury may contribute to neuroinflammation via astrocyte activation	23
TREM2‐induced activation of microglia contributes to synaptic integrity in cognitively intact aged individuals with Alzheimer's neuropathology	22
A Zika virus primary isolate induces neuroinflammation, compromises the blood‐brain barrier and upregulates CXCL12 in adult macaques	20
The use and limitations of single‐cell mass cytometry for studying human microglia function	20
Distribution of tau hyperphosphorylation in canine dementia resembles early Alzheimer’s disease and other tauopathies	20
Ependymoma‐like tumor with mesenchymal differentiation harboring C11orf95‐NCOA1/2 or ‐RELA fusion: A hitherto unclassified tumor related to ependymoma	19
Isoform‐specific upregulation of FynT kinase expression is associated with tauopathy and glial activation in Alzheimer's disease and Lewy body dementias	19
Hypothesis review: Alzheimer's overture guidelines	19
PKR kinase directly regulates tau expression and Alzheimer's disease‐related tau phosphorylation	19
Denser brain capillary network with preserved pericytes in Alzheimer's disease	19
Pediatric meningioma: a clinicopathologic and molecular study with potential grading implications	18
Unfolded protein response activation in C9orf72 frontotemporal dementia is associated with dipeptide pathology and granulovacuolar degeneration in granule cells	18
Inflammatory features in sporadic late‐onset nemaline myopathy are independent from monoclonal gammopathy	17
Accumulation of cellular prion protein within β‐amyloid oligomer plaques in aged human brains	17
Distinct circular RNA expression profiles in pediatric ependymomas	17
Evaluating the performance of large language models: ChatGPT and Google Bard in generating differential diagnoses in clinicopathological conferences of neurodegenerative disorders	17
Mitochondrial DNA variants in inclusion body myositis characterized by deep sequencing	16
Extralysosomal cathepsin B in central nervous system: Mechanisms and therapeutic implications	16
Diverse changes in microglia morphology and axonal pathology during the course of 1 year after mild traumatic brain injury in pigs	16
Effect of olfactory bulb pathology on olfactory function in normal aging	16
Histopathological patterns in atypical teratoid/rhabdoid tumors are related to molecular subgroup	16
Contribution of the astrocytic tau pathology to synapse loss in progressive supranuclear palsy and corticobasal degeneration	15
Fibrinogen in the glioblastoma microenvironment contributes to the invasiveness of brain tumor‐initiating cells	15
A deep learning‐based model for prediction of hemorrhagic transformation after stroke	15
Multiple system atrophy variant with severe hippocampal pathology	15
Reconstituting neurovascular unit with primary neural stem cells and brain microvascular endothelial cells in three‐dimensional matrix	15
Congenital tumors of the central nervous system: an institutional review of 64 cases with emphasis on tumors with unique histologic and molecular characteristics	14
An integrative histopathological and epigenetic characterization of primary intracranial mesenchymal tumors, FET:CREB‐fused broadening the spectrum of tumor entities in comparison with their soft tiss	14
Aged Tmem106b knockout mice display gait deficits in coincidence with Purkinje cell loss and only limited signs of non‐motor dysfunction	14
Neuropathological profile of long‐duration amyotrophic lateral sclerosis in military Veterans	14
Novel genetic variants in MAPT and alterations in tau phosphorylation in amyotrophic lateral sclerosis post‐mortem motor cortex and cerebrospinal fluid	14
Integrated genotype–phenotype analysis of long‐term epilepsy‐associated ganglioglioma	14
Proteomic analysis of human hippocampal subfields provides new insights into the pathogenesis of Alzheimer’s disease and the role of glial cells	14
Oligodendrocyte‐specific deletion of FGFR2 ameliorates MOG_35‐55‐induced EAE through ERK and Akt signalling	13
Independent distribution between tauopathy secondary to subacute sclerotic panencephalitis and measles virus: An immunohistochemical analysis in autopsy cases including cases treated with aggressive a	13
Edematous myositis: a clinical presentation first suggesting dermatomyositis diagnosis	13
The association between neurodegeneration and local complement activation in the thalamus to progressive multiple sclerosis outcome	13

A novel temporal‐predominant neuro‐astroglial tauopathy associated with TMEM106B gene polymorphism in FTLD/ALS‐TDP	13
Neonatal apneic phenotype in a murine congenital central hypoventilation syndrome model is induced through non‐cell autonomous developmental mechanisms	13
Inactivation of the CB₂ receptor accelerated the neuropathological deterioration in TDP‐43 transgenic mice, a model of amyotrophic lateral sclerosis	13
Molecular diagnostics in drug‐resistant focal epilepsy define new disease entities	13
Investigating the presence of doubly phosphorylated α‐synuclein at tyrosine 125 and serine 129 in idiopathic Lewy body diseases	13
Association of CD2AP neuronal deposits with Braak neurofibrillary stage in Alzheimer’s disease	13
Pathological tau signatures and nuclear alterations in neurons, astrocytes and microglia in Alzheimer's disease, progressive supranuclear palsy, and dementia with Lewy bodies	13
Focal cortical dysplasia type 1	12
NanoString technology distinguishes anti‐TIF‐1γ⁺ from anti‐Mi‐2⁺ dermatomyositis patients	12
Region‐specific preservation of Purkinje cell morphology and motor behavior in the ATXN1[82Q] mouse model of spinocerebellar ataxia 1	12
Factors associated with development and distribution of granular/fuzzy astrocytes in neurodegenerative diseases	12
Neuropathology of COVID‐19: where are the neuropathologists?	12
Considerations for integrative multi‐omic approaches to explore Alzheimer's disease mechanisms	12
Downregulated GPR30 expression in the epileptogenic foci of female patients with focal cortical dysplasia type IIb and tuberous sclerosis complex is correlated with ¹⁸F‐FDG PET‐CT values	12
Mini‐symposium in medulloblastoma genomics in the modern molecular era	12
Identification of inflammasome signaling proteins in neurons and microglia in early and intermediate stages of Alzheimer's disease	12
Differential diagnosis of vacuolar myopathies in the NGS era	12
Glial activation in prion diseases is selectively triggered by neuronal PrP^Sc	11
The fate of interneurons, GABA_A receptor sub‐types and perineuronal nets in Alzheimer's disease	11
Stimulation of retrotrapezoid nucleus Phox2b‐expressing neurons rescues breathing dysfunction in an experimental Parkinson’s disease rat model	11
Axonal injury following mild traumatic brain injury is exacerbated by repetitive insult and is linked to the delayed attenuation of NeuN expression without concomitant neuronal death in the mouse	11
Distinct microglial and macrophage distribution patterns in the concentric and lamellar lesions in Baló's disease and neuromyelitis optica spectrum disorders	11
RAB39B is redistributed in dementia with Lewy bodies and is sequestered within aβ plaques and Lewy bodies	11
Cognitive decline in amyotrophic lateral sclerosis: Neuropathological substrate and genetic determinants	11
Embryonal and non‐meningothelial mesenchymal tumors of the central nervous system – Advances in diagnosis and prognostication	11
Motor neuron involvement expands the neuropathological phenotype of late‐onset ataxia in RFC1 mutation (CANVAS)	11
The molecular etiology of Alzheimer’s disease	11
Variability in the type and layer distribution of cortical Aβ pathology in familial Alzheimer’s disease	11
High‐dose biotin restores redox balance, energy and lipid homeostasis, and axonal health in a model of adrenoleukodystrophy	11
Impact of α‐synuclein spreading on the nigrostriatal dopaminergic pathway depends on the onset of the pathology	11
Expanding the spectrum of EWSR1‐PATZ1 rearranged CNS tumors: An infantile case with leptomeningeal dissemination	11
Intracranial mesenchymal tumors with FET‐CREB fusion are composed of at least two epigenetic subgroups distinct from meningioma and extracranial sarcomas	10
Heterogeneity of cellular inflammatory responses in ageing white matter and relationship to Alzheimer’s and small vessel disease pathologies	10
Molecular neuropathology of brain‐invasive meningiomas	10
Use of advanced neuroimaging and artificial intelligence in meningiomas	10
Upregulation of the pathogenic transcription factor SPI1/PU.1 in tuberous sclerosis complex and focal cortical dysplasia by oxidative stress	10
The epigenetic mechanisms involved in mitochondrial dysfunction: Implication for Parkinson’s disease	10
Targeting the interaction of GABA_B receptors with CaMKII with an interfering peptide restores receptor expression after cerebral ischemia and inhibits progressive neuronal death in mouse br	10