International Journal of Oncology

Article	Citations
Triple‑negative breast cancer therapy: Current and future perspectives (Review)	206
Anticancer peptide: Physicochemical property, functional aspect and trend in clinical application (Review)	184
Mechanisms and management of 3rd‑generation EGFR‑TKI resistance in advanced non‑small cell lung cancer (Review)	102
Cutaneous melanoma and the immunotherapy revolution (Review)	74
Serine, glycine and one‑carbon metabolism in cancer (Review)	71
A multidisciplinary approach remains the best strategy to improve and strengthen the management of ovarian cancer (Review)	66
Cancer‑associated fibroblast‑induced M2‑polarized macrophages promote hepatocellular carcinoma progression via the plasminogen activator inhibitor‑1 pathway	63
Current molecular and clinical insights into uveal melanoma (Review)	53
Artificial intelligence radiogenomics for advancing precision and effectiveness in oncologic care (Review)	51
Immune-checkpoint inhibitors from cancer to COVID‑19: A promising avenue for the treatment of patients with COVID‑19 (Review)	50
High expression of immune checkpoints is associated with the TIL load, mutation rate and patient survival in colorectal cancer	49
Butyrate enhances the efficacy of radiotherapy via FOXO3A in colorectal cancer patient‑derived organoids	43
Update on uveal melanoma: Translational research from biology to clinical practice (Review)	37
N6‑methyladenosine upregulates miR‑181d‑5p in exosomes derived from cancer‑associated fibroblasts to inhibit 5‑FU sensitivity by targeting NCALD in colorectal cancer	35
Probiotic‑derived ferrichrome inhibits the growth of refractory pancreatic cancer cells	35
Human‑made electromagnetic fields: Ion forced‑oscillation and voltage‑gated ion channel dysfunction, oxidative stress and DNA damage (Review)	34
Activation of PGK1 under hypoxic conditions promotes glycolysis and increases stem cell‑like properties and the epithelial‑mesenchymal transition in oral squamous cell carcinoma cells via the AKT sign	34
Pan‑cancer analysis of transmembrane protease serine 2 and cathepsin L that mediate cellular SARS‑CoV‑2 infection leading to COVID-19	32
Riluzole: A neuroprotective drug with potential as a novel anti‑cancer agent (Review)	31
‘Reverse Warburg effect’ of cancer‑associated fibroblasts (Review)	30
Signaling pathways and therapeutic approaches in glioblastoma multiforme (Review)	29
Long non‑coding RNA FEZF1‑AS1 facilitates non‑small cell lung cancer progression via the ITGA11/miR‑516b‑5p axis	28
NUPR1 and its potential role in cancer and pathological conditions (Review)	28
Curcumin inhibits the cancer‑associated fibroblast‑derived chemoresistance of gastric cancer through the suppression of the JAK/STAT3 signaling pathway	28
Effects of curcumin complexes on MDA‑MB‑231 breast cancer cell proliferation	27

Doxorubicin and CD‑CUR inclusion complex co‑loaded in thermosensitive hydrogel PLGA‑PEG‑PLGA localized administration for osteosarcoma	27
Role of taurine, its haloamines and its lncRNA TUG1 in both inflammation and cancer progression. On the road to therapeutics? (Review)	26
Characterization of KIF20A as a prognostic biomarker and therapeutic target for different subtypes of breast cancer	26
Critical role of mTOR in regulating aerobic glycolysis in carcinogenesis (Review)	25
Long non‑coding RNA nuclear paraspeckle assembly transcript 1 regulates ionizing radiation‑induced pyroptosis via microRNA‑448/gasdermin E in colorectal cancer cells	25
Regulatory effect of the MAFG‑AS1/miR‑150‑5p/MYB axis on the proliferation and migration of breast cancer cells	24
GBP1 promotes erlotinib resistance via PGK1‑activated EMT signaling in non‑small cell lung cancer	24
Role of macrophages in tumor progression and therapy (Review)	24
DNA methylation and breast cancer: A way forward (Review)	23
MUC1 is an oncoprotein with a significant role in apoptosis (Review)	23
Sequestosome 1/p62: A multitasker in the regulation of malignant tumor aggression (Review)	23
Underlying metastasis mechanism and clinical application of exosomal circular RNA in tumors (Review)	23
Protective effects of combined treatment with mild hypothermia and edaravone against cerebral ischemia/reperfusion injury via oxidative stress and Nrf2 pathway regulation	22
Novel PI3K/Akt/mTOR signaling inhibitor, W922, prevents colorectal cancer growth via the regulation of autophagy	22
Exosomal transfer of miR‑25‑3p promotes the proliferation and temozolomide resistance of glioblastoma cells by targeting FBXW7	21
Association of the microbiome with colorectal cancer development (Review)	21
Roles of exosomes in cancer chemotherapy resistance, progression, metastasis and immunity, and their clinical applications (Review)	20
Collagen type VI‑α1 and 2 repress the proliferation, migration and invasion of bladder cancer cells	20
Novel circRNA_0071196/miRNA‑19b‑3p/CIT axis is associated with proliferation and migration of bladder cancer	19
Role of Nectin‑4 protein in cancer (Review)	19
The TLR4/ERK/PD‑L1 axis may contribute to NSCLC initiation	19
Isoorientin induces the apoptosis and cell cycle arrest of A549 human lung cancer cells via the ROS‑regulated MAPK, STAT3 and NF‑κB signaling pathways	19
Identification of the most common BRCA alterations through analysis of germline mutation databases: Is droplet digital PCR an additional strategy for the assessment of such alterations in breast and o	18
Crosstalk between YAP and TGFβ regulates SERPINE1 expression in mesenchymal lung cancer cells	18
Biomarkers of tumor invasiveness in proteomics (Review)	18
Emerging roles and mechanisms of microRNA‑222‑3p in human cancer (Review)	18
Clinical crosstalk between microRNAs and gastric cancer (Review)	18
SMYD3 overexpression indicates poor prognosis and promotes cell proliferation, migration and invasion in non‑small cell lung cancer	18
Metformin impairs cisplatin resistance effects in A549 lung cancer cells through mTOR signaling and other metabolic pathways	17
PLOD2-driven IL-6/STAT3 signaling promotes the invasion and metastasis of oral squamous cell carcinoma via activation of integrin β1	17
Neural stem cell‑derived exosomes transfer miR‑124‑3p into cells to inhibit glioma growth by targeting FLOT2	17
Novel insights on gut microbiota manipulation and immune checkpoint inhibition in cancer (Review)	17
Chitinase 3-like 1 secreted from cancer-associated fibroblasts promotes tumor angiogenesis via interleukin-8 secretion in colorectal cancer	17
[Erratum] circRNA_001275 upregulates Wnt7a expression by competitively sponging miR‑370‑3p to promote cisplatin resistance in esophageal cancer	17
lncRNA cytoskeleton regulator reduces non‑small cell lung cancer radiosensitivity by downregulating miRNA‑206 and activating prothymosin α	17
CircRNA hsa_circ_0070934 functions as a competitive endogenous RNA to regulate HOXB7 expression by sponging miR‑1236‑3p in cutaneous squamous cell carcinoma	17
Interleukin‑8 released by cancer‑associated fibroblasts attenuates the autophagy and promotes the migration of ovarian cancer cells	17
MicroRNA‑103a‑3p promotes metastasis by targeting TPD52 in salivary adenoid cystic carcinoma	17
Ribosome 18S m6A methyltransferase METTL5 promotes pancreatic cancer progression by modulating c‑Myc translation	17
CYP11A1‑derived vitamin D hydroxyderivatives as candidates for therapy of basal and squamous cell carcinomas	16
Everolimus therapy and side‑effects: A systematic review and meta‑analysis	16
Effects of PI3K and FGFR inhibitors alone and in combination, and with/without cytostatics in childhood neuroblastoma cell lines	16
Overall survival in stage IV EGFR mutation‑positive NSCLC: Comparing first‑, second‑ and third‑generation EGFR‑TKIs (Review)	16
Genomic characterization of five commonly used endometrial cancer cell lines	16
WBSCR22 and TRMT112 synergistically suppress cell proliferation, invasion and tumorigenesis in pancreatic cancer via transcriptional regulation of ISG15	16
Correlation of SARS‑CoV‑2 to cancer: Carcinogenic or anticancer? (Review)	16
Research status and prospects of biomarkers for nasopharyngeal carcinoma in the era of high‑throughput omics (Review)	16
TGF‑β inhibitor RepSox suppresses osteosarcoma via the JNK/Smad3 signaling pathway	16
Three‑dimensional models to study breast cancer (Review)	15
Diagnosis, prognosis and treatment of primary central nervous system lymphoma in the elderly population (Review)	15

circUBAP2 regulates osteosarcoma progression via the miR‑204‑3p/HMGA2 axis	15
High‑throughput screening identification of a small‑molecule compound that induces ferroptosis and attenuates the invasion and migration of hepatocellular carcinoma cells by targeting the STAT3/GPX4 a	15
Exosomes released by imatinib‑resistant K562 cells contain specific membrane markers, IFITM3, CD146 and CD36 and increase the survival of imatinib‑sensitive cells in the presence of imatinib	15
MicroRNA‑137 regulates hypoxia‑mediated migration and epithelial‑mesenchymal transition in prostate cancer by targeting LGR4 via the EGFR/ERK signaling pathway	14
Cholesterol metabolism in drug‑resistant cancer (Review)	14
Resveratrol modulates the apoptosis and autophagic death of human lung adenocarcinoma A549 cells via a p53‑dependent pathway: Integrated bioinformatics analysis and experimental validation	14
Targeting cancer stem cells in cholangiocarcinoma (Review)	14
Silencing IDO2 in dendritic cells: A novel strategy to strengthen cancer immunotherapy in a murine lung cancer model	14
Lactoferrin may inhibit the development of cancer via its immunostimulatory and immunomodulatory activities	14
Stromal cells in the tumor microenvironment promote the progression of oral squamous cell carcinoma	14
Elevation of ADAM12 facilitates tumor progression by enhancing metastasis and immune infiltration in gastric cancer	14
Macrolide antibiotics enhance the antitumor effect of lansoprazole resulting in lysosomal membrane permeabilization‑associated cell death	14
Activin A triggers angiogenesis via regulation of VEGFA and its overexpression is associated with poor prognosis of oral squamous cell carcinoma	14
SEPT6 drives hepatocellular carcinoma cell proliferation, migration and invasion via the Hippo/YAP signaling pathway	13
Lumican mediates HTB94 chondrosarcoma cell growth via an IGF‑IR/Erk1/2 axis	13
Increased expression of PSME2 is associated with clear cell renal cell carcinoma invasion by regulating BNIP3‑mediated autophagy	13
Cutaneous melanoma dissemination is dependent on the malignant cell properties and factors of intercellular crosstalk in the cancer microenvironment (Review)	13
Shikonin suppresses colon cancer cell growth and exerts synergistic effects by regulating ADAM17 and the IL‑6/STAT3 signaling pathway	13
Epigallocatechin‑3‑gallate hinders metabolic coupling to suppress colorectal cancer malignancy through targeting aerobic glycolysis in cancer‑associated fibroblasts	13
lncRNA SNHG22 sponges miR‑128‑3p to promote the progression of colorectal cancer by upregulating E2F3	13
Exosomal proteins: Key players mediating pre‑metastatic niche formation and clinical implications (Review)	12
FAM83A exerts tumor‑suppressive roles in cervical cancer by regulating integrins	12
Noggin is associated with a poor prognosis of gastric cancer by promoting the proliferation of gastric cancer cells via the upregulation of EGFR	12
Targeting the mTOR pathway using novel ATP‑competitive inhibitors, Torin1, Torin2 and XL388, in the treatment of glioblastoma	12
lncRNA ST3GAL6‑AS1 promotes invasion by inhibiting hnRNPA2B1‑mediated ST3GAL6 expression in multiple myeloma	12
Potential of antiviral drug oseltamivir for the treatment of liver cancer	12
The TLR7/8 agonist R848 optimizes host and tumor immunity to improve therapeutic efficacy in murine lung cancer	12
Combined inhibition of IL‑6 and IL‑8 pathways suppresses ovarian cancer cell viability and migration and tumor growth	12
NcRNAs: Multi‑angle participation in the regulation of glioma chemotherapy resistance (Review)	12
Cellular metabolism in pancreatic cancer as a tool for prognosis and treatment (Review)	12
Isolation and analysis of tumor‑derived extracellular vesicles from head and neck squamous cell carcinoma plasma by galectin‑based glycan recognition particles	12
Potential of the tumor‑derived extracellular vesicles carrying the miR‑125b‑5p target TNFAIP3 in reducing the sensitivity of diffuse large B cell lymphoma to rituximab	12
Epigenetic modification regulates tumor progression and metastasis through EMT (Review)	12
Parthenolide inhibits the tumor characteristics of renal cell carcinoma	12
Menin‑MLL inhibitors induce ferroptosis and enhance the anti‑proliferative activity of auranofin in several types of cancer cells	12
Glioma cells are resistant to inflammation‑induced alterations of mitochondrial dynamics	11
Exosomal ANXA1 derived from thyroid cancer cells is associated with malignant transformation of human thyroid follicular epithelial cells by promoting cell proliferation	11
Immunological modulation of the Th1/Th2 shift by ionizing radiation in tumors (Review)	11
Blocking the Wnt/β‑catenin signaling pathway to treat colorectal cancer: Strategies to improve current therapies (Review)	11
Dexamethasone inhibits stemness maintenance and enhances chemosensitivity of hepatocellular carcinoma stem cells by inducing deSUMOylation of HIF‑1α and Oct4	11
TRIM35 ubiquitination regulates the expression of PKM2 tetramer and dimer and affects the malignant behaviour of breast cancer by regulating the Warburg effect	11
Downregulation of METTL6 mitigates cell progression, migration, invasion and adhesion in hepatocellular carcinoma by inhibiting cell adhesion molecules	11
The long non‑coding RNA CASC7 inhibits growth and invasion of non‑small cell lung cancer cells through phosphatase and tensin homolog upregulation via sequestration of miR‑92a	11
Hypoplastic myelodysplastic syndrome and acquired aplastic anemia: Immune‑mediated bone marrow failure syndromes (Review)	11
lncRNA HCP5 acts as a ceRNA to regulate EZH2 by sponging miR‑138‑5p in cutaneous squamous cell carcinoma	11
Circadian clock as a possible control point in colorectal cancer progression (Review)	11
circ‑LRP6 contributes to osteosarcoma progression by regulating the miR‑141‑3p/HDAC4/HMGB1 axis	11
METTL3 antagonizes 5‑FU chemotherapy and confers drug resistance in colorectal carcinoma	11
MicroRNA‑301a/ZNRF3/wnt/β‑catenin signal regulatory crosstalk mediates glioma progression	11
Digitoxin inhibits HeLa cell growth through the induction of G2/M cell cycle arrest and apoptosis in vitro and in vivo	11
New insights into the management of differentiated thyroid carcinoma in children and adolescents (Review)	11
LncCCAT1 interaction protein PKM2 upregulates SREBP2 phosphorylation to promote osteosarcoma tumorigenesis by enhancing the Warburg effect and lipogenesis	11
Anterior gradient protein 2 is a marker of tumor aggressiveness in breast cancer and favors chemotherapy‑induced senescence escape	10
Doramectin inhibits glioblastoma cell survival via regulation of autophagy in vitro and in vivo	10
LINC00514 promotes lipogenesis and tumor progression in esophageal squamous cell carcinoma by sponging miR‑378a‑5p to enhance SPHK1 expression	10
Liproxstatin‑1 induces cell cycle arrest, apoptosis, and caspase‑3/GSDME‑dependent secondary pyroptosis in K562 cells	10
Dual inhibition of EGFR‑VEGF: An effective approach to the treatment of advanced non‑small cell lung cancer with EGFR mutation (Review)	10
Efficacy of birinapant in combination with carboplatin in targeting platinum‑resistant epithelial ovarian cancers	10
Roles of Rho‑associated kinase in lung cancer (Review)	10
Long non‑coding RNA LUCAT1 contributes to cisplatin resistance by regulating the miR‑514a‑3p/ULK1 axis in human non‑small cell lung cancer	10
Retrospective analysis of the preparation and application of immunotherapy in cancer treatment (Review)	10
DYRK1A suppression attenuates HIF‑1α accumulation and enhances the anti‑liver cancer effects of regorafenib and sorafenib under hypoxic conditions	10
Role of telomere length in human carcinogenesis (Review)	10
Galectin‑1 binds GRP78 to promote the proliferation and metastasis of gastric cancer	10
Recent progress of circular RNAs in different types of human cancer: Technological landscape, clinical opportunities and challenges (Review)	10
Upregulation of miRNA‑301a‑3p promotes tumor progression in gastric cancer by suppressing NKRF and activating NF‑κB signaling	10
Roles of small extracellular vesicles in the development, diagnosis and possible treatment strategies for hepatocellular carcinoma (Review)	10
Inhibitory effects of canagliflozin on pancreatic cancer are mediated via the downregulation of glucose transporter‑1 and lactate dehydrogenase A	9
MicroRNA‑93 knockdown inhibits acute myeloid leukemia cell growth via inactivating the PI3K/AKT pathway by upregulating DAB2	9
Use of conditional reprogramming cell, patient derived xenograft and organoid for drug screening for individualized prostate cancer therapy: Current and future perspectives (Review)	9
Matrix metalloproteinase‑1 expression is regulated by HIF‑1‑dependent and epigenetic mechanisms and serves a tumor‑suppressive role in gastric cancer progression	9
Glioma‑neuronal interactions in tumor progression: Mechanism, therapeutic strategies and perspectives (Review)	9
Novel therapies for malignant pleural effusion: Anti‑angiogenic therapy and immunotherapy (Review)	9
Research progress on immunotherapy in triple‑negative breast cancer (Review)	9
Guanosine monophosphate synthase upregulation mediates cervical cancer progression by inhibiting the apoptosis of cervical cancer cells via the Stat3/P53 pathway	9
High expression of FUSE binding protein 1 in breast cancer stimulates cell proliferation and diminishes drug sensitivity	9
Role of the tumor microenvironment in cancer hallmarks and targeted therapy (Review)	9
Knockdown of TMED3 inhibits cell viability and migration and increases apoptosis in human chordoma cells	9
Long non‑coding RNA 01614 hyperactivates WNT/β‑catenin signaling to promote pancreatic cancer progression by suppressing GSK‑3β	9
Cisplatin enhances protein O‑GlcNAcylation by altering the activity of OGT, OGA and AMPK in human non‑small cell lung cancer cells	9

lncRNA GAS5, as a ceRNA, inhibits the proliferation of diffuse large B‑cell lymphoma cells by regulating the miR‑18a‑5p/RUNX1 axis	9
Ricolinostat enhances adavosertib‑induced mitotic catastrophe in TP53‑mutated head and neck squamous cell carcinoma cells	9
CXCR4 blockade sensitizes osteosarcoma to doxorubicin by inducing autophagic cell death via PI3K‑Akt‑mTOR pathway inhibition	9
Macrophage migration inhibitory factor in the pathogenesis of leukemia (Review)	9
miR‑383 increases the cisplatin sensitivity of lung adenocarcinoma cells through inhibition of the RBM24‑mediated NF‑κB signaling pathway	9