Inflammation Research

Article	Citations
News	259
IL10/AMPK pathway was associated with the hippocampal anti-inflammatory response to high-sugar and high-fat diet withdrawal	181
Beyond CYP2C19: inflammation and angiogenesis gene variants drive clopidogrel resistance in CAD patients	143
Immunity-related GTPase IRGM at the intersection of autophagy, inflammation, and tumorigenesis	75
The role of fatty acid metabolism on B cells and B cell-related autoimmune diseases	73
Immune-related genetic single-nucleotide polymorphisms contribute to prognosis and response to chemotherapy in patients with acute lymphoblastic leukemia	65
Viperin inhibits interferon-γ production to promote Mycobacterium tuberculosis survival by disrupting TBK1-IKKε-IRF3-axis and JAK-STAT signaling	63
Paradoxical expression of NRP1 in decidual stromal and immune cells reveals a novel inflammation balancing mechanism during early pregnancy	61
Kinin B1 receptor and TLR4 interaction in inflammatory response	60
The role of dietary fibre in lung inflammation: microbiota, metabolites, and immune crosstalk	59
HMGB1: key mediator in digestive system diseases	59
Clinical outcomes of anti-inflammatory therapies inhibiting the NLRP3/IL-1β/IL-6/CRP pathway in coronary artery disease patients: a systemic review and meta-analysis of 37,056 individuals from 32 rand	58
Loss of TRIM24 promotes IL-10 expression via CBP/p300-dependent IFNβ1 transcription during macrophage activation	53
From bench to bedside: targeting lymphocyte activation gene 3 as a therapeutic strategy for autoimmune diseases	48
Inhibition of glycolytic reprogramming suppresses innate immune-mediated inflammation in experimental amyotrophic lateral sclerosis	46
Single-cell hdWGCNA reveals a novel diagnostic model and signature genes of macrophages associated with chronic obstructive pulmonary disease	45
Serum from COVID-19 patients promotes endothelial cell dysfunction through protease-activated receptor 2	45
Unveiling the role of ABI3 and hub senescence-related genes in macrophage senescence for atherosclerotic plaque progression	44
IL-33, a neutrophil extracellular trap-related gene involved in the progression of diabetic kidney disease	43
Viperin deficiency promotes dendritic cell activation and function via NF-kappaB activation during Mycobacterium tuberculosis infection	43
CD20+ T cells: an emerging T cell subset in human pathology	42
Association of risk of incident acne and treatment with systemic Janus kinase inhibitors in atopic dermatitis: a systematic review and meta-analysis	41
Tissue-resident immune cells in the pathogenesis of multiple sclerosis	40
The NADase CD38 is a central regulator in gouty inflammation and a novel druggable therapeutic target	39
Long-chain acyl-CoA synthetase 4-mediated mitochondrial fatty acid metabolism and dendritic cell antigen presentation	39

Mitochondrial damage causes inflammation via cGAS-STING signaling in ketamine-induced cystitis	37
A pain from the nose to the head: neurological commitment during long COVID	35
IL-1 receptor antagonist: etiological and drug delivery systems overview	35
Annexin A1 is crucial during Toxoplasma gondii infection promoting the modulation of inflammation and intestinal and central nervous system barrier functions	34
Navigating the complex landscape of DPP4 inhibition in inflammation: from novel mechanisms to unresolved translational challenges	32
Successful treatment of refractory erythrodermic pemphigus foliaceus with low-dose rituximab and intravenous immunoglobulin	32
LncGBP9 knockdown alleviates myocardial inflammation and apoptosis in mice with acute viral myocarditis via suppressing NF-κB signaling pathway	32
Internalization of benzylisoquinoline alkaloids by resting and activated bone marrow-derived mast cells utilizes energy-dependent mechanisms	31
Extracellular histones induce inflammation and senescence of vascular smooth muscle cells by activating the AMPK/FOXO4 signaling pathway	31
Treg plasticity and human diseases	30
Mitochondrial proteomics reveals the impact of Estrogen in enhancing energy metabolism of patient-derived fibroblast-like synoviocytes in rheumatoid arthritis	30
Caffeine alleviates acute liver injury by inducing the expression of NEDD4L and deceasing GRP78 level via ubiquitination	30
Antigen-specific reduced IgG inhibits cellular response in rat basophilic leukemia cells activated with multivalent antigen	29
Infliximab modifies CD74-mediated lymphatic abnormalities and adipose tissue alterations in creeping fat of Crohn’s disease	28
Acute lung injury: a view from the perspective of necroptosis	28
The HMGB1-RAGE axis induces apoptosis in acute respiratory distress syndrome through PERK/eIF2α/ATF4-mediated endoplasmic reticulum stress	28
Functional characterization of novel anti-DEFA5 monoclonal antibody clones 1A8 and 4F5 in inflammatory bowel disease colitis tissues	27
Immune response associated with ischemia and reperfusion injury during organ transplantation	27
A suitable model to investigate acute neurological consequences of coronavirus infection	26
Dog allergen-induced asthma in mice: a relevant model of T2low severe asthma with airway remodelling	24
Identification of RRM2 as a key ferroptosis-related gene in sepsis	24
USP7 accelerates FMR1-mediated ferroptosis by facilitating TBK1 ubiquitination and DNMT1 deubiquitination after renal ischemia–reperfusion injury	24
SIRT6 inhibits endoplasmic reticulum stress-mediated ferroptosis by activating Nrf2/HO-1 signaling to alleviate osteoarthritis	23
Identification of ferroptosis-related genes and potential drugs in osteoarthritis	23
Systemic inflammation, neuroinflammation and perioperative neurocognitive disorders	23
Piezo1 exacerbates psoriasis by promoting macrophage M1 polarization and inhibits autophagy via activating PI3K/AKT signaling pathway	23
Quercetin and Kaempferol inhibit HMC-1 activation via SOCE/NFATc2 signaling and suppress hippocampal mast cell activation in lipopolysaccharide-induced depressive mice	22
Disulfidptosis-related genes RPN1 inhibits the progression of hepatocellular carcinoma by regulating cell cycle, may be a new therapeutic targets	22
Inflammation, coagulation, and cellular injury in heat-induced shock	21
Systemic immune inflammation index with all-cause and cause-specific mortality: a meta-analysis	21
SS-31 inhibits mtDNA–cGAS–STING signaling to improve POCD by activating mitophagy in aged mice	21
Alleviated NCOA4-mediated ferritinophagy protected RA FLSs from ferroptosis in lipopolysaccharide-induced inflammation under hypoxia	21
Retraction Note: Knockdown of long non‑coding RNA TUG1 depresses apoptosis of hippocampal neurons in Alzheimer’s disease by elevating microRNA‑15a and repressing ROCK1 expression	20
Prolonged effects of DPP-4 inhibitors on steato-hepatitic changes in Sprague–Dawley rats fed a high-cholesterol diet	20
Genetic correlations, shared risk genes and immunity landscapes between COVID-19 and venous thromboembolism: evidence from GWAS and bulk transcriptome data	20
Characterization of immune landscape and development of a novel N7-methylguanine-related gene signature to aid therapy in recurrent aphthous stomatitis	20
Granulocyte macrophage colony stimulating factor exerts dominant effects over macrophage colony stimulating factor during macrophage differentiation in vitro to induce an inflammatory phenotype	19
Human antimicrobial/host defense peptide LL-37 may prevent the spread of a local infection through multiple mechanisms: an update	19
Exocytic machineries differentially control mediator release from allergen-triggered RBL-2H3 cells	19
Prospective study of an adalimumab combined with partial enteral nutrition in the induction period of Crohn’s disease	19
Identification of inflammatory protein biomarkers for predicting the different subtype of adult with tuberculosis: an Olink proteomic study	19
Treatment with lipoxin A4 improves influenza A infection outcome, induces macrophage reprogramming, anti-inflammatory and pro-resolutive responses	19
The combination of metabolic syndrome and inflammation increased the risk of colorectal cancer	18
Inflammatory cell death PANoptosis is induced by the anti-cancer curaxin CBL0137 via eliciting the assembly of ZBP1-associated PANoptosome	18
USP10 regulates macrophage inflammation responses via stabilizing NEMO in LPS-induced sepsis	18
Inflammatory biomarkers on an LPS-induced RAW 264.7 cell model: a systematic review and meta-analysis	18
Roquin-1 interaction with Regnase-1 inhibits the progression of rheumatoid arthritis via suppressing FGF2 expression and NF-κB pathway	18
Commentaries: Lecanemab: pioneering the way as the first approved drug for Alzheimer’s disease treatment	17
SRY-related high-mobility group box 9 (SOX9) alleviates cigarette smoke extract (CSE)-induced inflammatory injury in human bronchial epithelial cells by suppressing stromal interaction molecule 1 (STI	17
Interlukin-23 inhibitors as an induction and maintenance therapy for moderate to severe ulcerative colitis: a systematic review and meta‑analysis of randomized controlled trials	17

Chronic ethanol exposure decreases H3K27me3 in the Il6 promoter region of macrophages and generates persistent dysfunction on neutrophils during fungal infection	17
Influence of homocysteine on regulating immunothrombosis: mechanisms and therapeutic potential in management of infections	17
IL-35 modulates Tfh2 and Tfr cell balance to alleviate allergic rhinitis	17
STAT1-mediated induction of Ly6c-expressing macrophages are involved in the pathogenesis of an acute colitis model	17
CD8 + T cell-based molecular subtypes with heterogeneous immune landscapes and clinical significance in acute myeloid leukemia	16
Minocycline alleviates microglia ferroptosis by inhibiting HO-1 during cerebral ischemia–reperfusion injury	16
Mechanosensitive ion channels and inflammation: key links in cellular signal transduction	16
Selective inhibition of PKR by C16 accelerates diabetic wound healing by inhibiting NALP3 expression in mice	16
Modulation of Plet1 expression by N-Acetylglucosamine through the IL-17 A-MAPK pathway in an imiquimod-induced psoriasis mouse model	16
The star target in SLE: IL-17	16
Salidroside alleviates cadmium-induced toxicity in mice by restoring the notch/HES-1 and RIP1-driven inflammatory signaling axis	16
Monogenic autoinflammatory disease-associated cardiac damage	16
Molecular biology of the novel anticancer medications: a focus on kinases inhibitors, biologics and CAR T-cell therapy	16
Mechanism of action of M-XQLD treatment for asthma: role of STARD13 in Th17 suppression	16
Environmental and inflammatory factors influencing concurrent gut and lung inflammation	15
IL-35 promotes IL-35+IL-10+ Bregs and Conventional LAG3+ Tregs in the lung tissue of OVA-Induced Asthmatic Mice	15
Challenges and opportunities in inflammatory bowel disease: from current therapeutic strategies to organoid-based models	15
Characterizing the kinetics of presepsin and associated inflammatory biomarkers in human endotoxemia	15
5-oxoETE promote thrombosis in antiphospholipid syndrome by triggering NETs formation through PLC/PKC/ERK pathway	15
The combination of machine learning and untargeted metabolomics identifies the lipid metabolism -related gene CH25H as a potential biomarker in asthma	15
Enhancing effect of sodium butyrate on phosphatidylserine–liposome-induced macrophage polarization	15
Single-cell transcriptome analysis of the mouse lungs during the injury and recovery periods after lipopolysaccharide administration	15
The molecular mechanisms of remodeling in asthma, COPD and IPF with a special emphasis on the complex role of Wnt5A	15
Prostacyclin synthase deficiency exacerbates systemic inflammatory responses in lipopolysaccharide-induced septic shock in mice	15
The role of regulatory T cells in vitiligo and therapeutic advances: a mini-review	15
Dexamethasone regulates gene expression in chondrocytes through MKP-1 and downregulates cholesterol hydroxylases CH25H and CYP7B1	15
COVID-19 pandemic: the delta variant, T-cell responses, and the efficacy of developing vaccines	15
Causal associations of circulating Helicobacter pylori antibodies with stroke and the mediating role of inflammation	14
Retraction Note: Emerging protective roles of shengmai injection in septic cardiomyopathy in mice by inducing myocardial mitochondrial autophagy via caspase-3/Beclin-1 axis	14
The clinical trajectory of peripheral blood immune cell subsets, T-cell activation, and cytokines in septic patients	14
Altered vacuole membrane protein 1 (VMP1) expression is associated with increased NLRP3 inflammasome activation and mitochondrial dysfunction	14
Miconazole attenuates LPS-induced lung inflammation by modulating alveolar macrophage polarization via promoting lipid metabolic reprogramming	14
Long-pulsed 1064-nm neodymium: yttrium-aluminum-garnet laser alleviates rosacea by improving lymphatic vessel dysfunction	14
Correction to: Fructose malabsorption in ChREBP-deficient mice disrupts the small intestine immune microenvironment and leads to diarrhea-dominant bowel habit changes	14
GCH1 reduces LPS-induced alveolar macrophage polarization and inflammation by inhibition of ferroptosis	14
MitoQ alleviates mitochondria damage in sepsis-acute lung injury in a citrate synthase dependent manner	14
Salmonella spvC gene suppresses macrophage/neutrophil antibacterial defense mediated by gasdermin D	14
Association of systemic immune-inflammation index and systemic inflammation response index with chronic kidney disease: observational study of 40,937 adults	14
Exploring macrophage and nerve interaction in endometriosis-associated pain: the inductive role of IL-33	14
The causal effect of natural killer cells on COVID-19 infection, hospitalization and severity	13
Histamine regulates the activity and the expression of the Na+/H+ exchanger (NHE)3 in human epithelial HK-2 cells	13
STING deficiency protects against wasp venom-induced acute kidney injury	13
Interleukin 15 and autoimmune disorders: pathophysiology, therapeutic potential, and clinical implications	13
Targeting ACE2 as a potential prophylactic strategy against COVID-19-induced exacerbation of chronic kidney disease	13
Recognition of Mycobacterium tuberculosis by macrophage Toll-like receptor and its role in autophagy	13
Transcriptomic analysis reveals molecular characterization and immune landscape of PANoptosis-related genes in atherosclerosis	13
Bone marrow mesenchymal stem cells-derived exosomes containing miR-539-5p inhibit pyroptosis through NLRP3/caspase-1 signalling to alleviate inflammatory bowel disease	13
Bioinformatics analysis for identifying micro-RNAs, long noncoding RNAs, transcription factors, and immune genes regulatory networks in diabetic cardiomyopathy using an integrated bioinformatics analy	13
Mediation of macrophage M1 polarization dynamics change by ubiquitin-autophagy-pathway regulated NLRP3 inflammasomes in PD-1 inhibitor-related myocardial inflammatory injury	13
Plant extracts and omega-3 supplementation modulate hippocampal oxylipin profile in response to LPS-induced neuroinflammation	13
Multimodal data-driven prognostic model for predicting new-onset ST-elevation myocardial infarction following emergency percutaneous coronary intervention	13
The potential roles of Th17 cells in the pathogenesis of oral lichen planus	12
Retraction Note to: Suppressors of cytokine signalling (SOCS)‑1 inhibits neuroinflammation by regulating ROS and TLR4 in BV2 cells	12
Rhein-attenuates LPS-induced acute lung injury via targeting NFATc1/Trem2 axis	12
Pentoxifylline in COVID-19 and considerations for its research in long COVID	12
The IL-6 autocrine loop promoting IFN-γ-induced fibroblast senescence is involved in psychological stress-mediated exacerbation of vitiligo	12
Annexin A1 (Ac2-26)-dependent Fpr2 receptor alleviates sepsis-induced acute kidney injury by inhibiting inflammation and apoptosis in vivo and in vitro	12
Histamine research advancements in the second year of the COVID-19 pandemic: report of the European Histamine Research Society (EHRS)	12
Causal role of myeloid cells in Parkinson’s disease: Mendelian randomization study	12
Biological attributes of zinc-dependent endopeptidases in endothelial dysfunction associated with sepsis: a narrative review	12
Simultaneously blocking ANGPTL3 and IL-1β for the treatment of atherosclerosis through lipid-lowering and anti-inflammation	12
Aryl hydrocarbon receptor (AhR) alleviates the LPS-induced inflammatory responses in IPEC-J2 cells by activating PINK1/Parkin-mediated mitophagy	12
Vitamin D3 suppresses NLRP3 inflammasome pathway and enhances steroid sensitivity in a neutrophilic steroid hyporesponsive asthma mouse model	12
Immunopathogenesis of urticaria: a clinical perspective on histamine and cytokine involvement	12
Screening inflammatory protein biomarkers on premature infants with necrotizing enterocolitis	12
Long-COVID fatigue is not predicted by pre-pandemic plasma IL-6 levels in mild COVID-19	12
Diamine oxidase knockout mice are not hypersensitive to orally or subcutaneously administered histamine	11
Lipoxin alleviates oxidative stress: a state-of-the-art review	11
Comprehensive analysis of single cell and bulk RNA sequencing reveals the heterogeneity of melanoma tumor microenvironment and predicts the response of immunotherapy	11
Exosomal PPARγ derived from macrophages suppresses LPS-induced peritonitis by negative regulation of CD14/TLR4 axis	11
Transgenic mice overexpressing human ALOX15 under the control of the aP2 promoter are partly protected in the complete Freund’s adjuvant-induced paw inflammation model	11
Agomir miRNA-150-5p alleviates pristane-induced lupus by suppressing myeloid dendritic cells activation and inflammation via TREM-1 axis	11
ADAM10-a “multitasker” in sepsis: focus on its posttranslational target	11
Calycosin inhibited MIF-mediated inflammatory chemotaxis of macrophages to ameliorate ischemia reperfusion-induced acute kidney injury	11
An antagonist of growth hormone-releasing hormone protects against LPS-induced increase of bronchoalveolar lavage fluid protein concentration	11
Group 2 innate lymphoid cells derived IL-9 reduces macrophage apoptosis and attenuates acute lung injury in sepsis	11
Alpha-galactosylceramide pre-treatment attenuates clinical symptoms of LPS-induced acute neuroinflammation by converting pathogenic iNKT cells to anti-inflammatory iNKT10 cells in the brain	11
Inhibition of PRMT6 reduces neomycin-induced inner ear hair cell injury through the restraint of FoxG1 arginine methylation	11
The role of IL-1 family of cytokines and receptors in pathogenesis of COVID-19	11
Transcriptomic profiling reveals a dramatic inflammatory shift in osteal macrophages during colitis-induced osteoporosis	11

Decoy oligonucleotides targeting NF-κB: a promising therapeutic approach for inflammatory diseases	11
Serine metabolism in macrophage polarization	11
Editorial expression of concern: Monocytes and lymphocytes as active participants in the pathogenesis of experimental shock	11
The purinergic signalling and inflammation in the pathogenesis and progression of diabetes: key factors and therapeutic targets	11
Bridging worlds: a narrative review of IL-17 at the crossroads of inflammation and thrombosis	11