Inflammation Research

Article	Citations
News	186
From bench to bedside: targeting lymphocyte activation gene 3 as a therapeutic strategy for autoimmune diseases	144
Loss of TRIM24 promotes IL-10 expression via CBP/p300-dependent IFNβ1 transcription during macrophage activation	103
Tissue-resident immune cells in the pathogenesis of multiple sclerosis	65
CHRFAM7A expression in mice increases resiliency after injury	55
IL10/AMPK pathway was associated with the hippocampal anti-inflammatory response to high-sugar and high-fat diet withdrawal	54
Inhibition of glycolytic reprogramming suppresses innate immune-mediated inflammation in experimental amyotrophic lateral sclerosis	51
HMGB1: key mediator in digestive system diseases	51
IL-33, a neutrophil extracellular trap-related gene involved in the progression of diabetic kidney disease	50
Mitochondrial damage causes inflammation via cGAS-STING signaling in ketamine-induced cystitis	49
Correction to: Circulating calprotectin as a supporting inflammatory marker in discriminating SARS-CoV-2 infection: an observational study	48
Association of risk of incident acne and treatment with systemic Janus kinase inhibitors in atopic dermatitis: a systematic review and meta-analysis	47
Kinin B1 receptor and TLR4 interaction in inflammatory response	45
Single-cell hdWGCNA reveals a novel diagnostic model and signature genes of macrophages associated with chronic obstructive pulmonary disease	44
Viperin deficiency promotes dendritic cell activation and function via NF-kappaB activation during Mycobacterium tuberculosis infection	42
Unveiling the role of ABI3 and hub senescence-related genes in macrophage senescence for atherosclerotic plaque progression	40
Immunity-related GTPase IRGM at the intersection of autophagy, inflammation, and tumorigenesis	38
Immune-related genetic single-nucleotide polymorphisms contribute to prognosis and response to chemotherapy in patients with acute lymphoblastic leukemia	38
Viperin inhibits interferon-γ production to promote Mycobacterium tuberculosis survival by disrupting TBK1-IKKε-IRF3-axis and JAK-STAT signaling	37
Paradoxical expression of NRP1 in decidual stromal and immune cells reveals a novel inflammation balancing mechanism during early pregnancy	35
Pseudomonas aeruginosa outer membrane vesicles ameliorates lung ischemia–reperfusion injury by regulating the balance of regulatory T cells and Th17 cells through Tim-3 and TLR4/NF-κB pathway	35
CD20+ T cells: an emerging T cell subset in human pathology	34
Serum from COVID-19 patients promotes endothelial cell dysfunction through protease-activated receptor 2	34
The NADase CD38 is a central regulator in gouty inflammation and a novel druggable therapeutic target	33
IL-1 receptor antagonist: etiological and drug delivery systems overview	33

Long-chain acyl-CoA synthetase 4-mediated mitochondrial fatty acid metabolism and dendritic cell antigen presentation	33
The role of fatty acid metabolism on B cells and B cell-related autoimmune diseases	33
A suitable model to investigate acute neurological consequences of coronavirus infection	32
Extracellular histones induce inflammation and senescence of vascular smooth muscle cells by activating the AMPK/FOXO4 signaling pathway	31
The role of 5-lipoxygenase in the pathophysiology of COVID-19 and its therapeutic implications	30
The HMGB1-RAGE axis induces apoptosis in acute respiratory distress syndrome through PERK/eIF2α/ATF4-mediated endoplasmic reticulum stress	30
Functional characterization of novel anti-DEFA5 monoclonal antibody clones 1A8 and 4F5 in inflammatory bowel disease colitis tissues	29
Caffeine alleviates acute liver injury by inducing the expression of NEDD4L and deceasing GRP78 level via ubiquitination	29
Internalization of benzylisoquinoline alkaloids by resting and activated bone marrow-derived mast cells utilizes energy-dependent mechanisms	29
Infliximab modifies CD74-mediated lymphatic abnormalities and adipose tissue alterations in creeping fat of Crohn’s disease	28
LncGBP9 knockdown alleviates myocardial inflammation and apoptosis in mice with acute viral myocarditis via suppressing NF-κB signaling pathway	28
Acute lung injury: a view from the perspective of necroptosis	28
A case of reactivation of varicella–zoster virus after BNT162b2 vaccine second dose?	27
Immune response associated with ischemia and reperfusion injury during organ transplantation	27
Treg plasticity and human diseases	27
Systemic immune inflammation index with all-cause and cause-specific mortality: a meta-analysis	26
USP7 accelerates FMR1-mediated ferroptosis by facilitating TBK1 ubiquitination and DNMT1 deubiquitination after renal ischemia–reperfusion injury	26
Dog allergen-induced asthma in mice: a relevant model of T2low severe asthma with airway remodelling	25
Quercetin and Kaempferol inhibit HMC-1 activation via SOCE/NFATc2 signaling and suppress hippocampal mast cell activation in lipopolysaccharide-induced depressive mice	25
Identification of RRM2 as a key ferroptosis-related gene in sepsis	25
Identification of ferroptosis-related genes and potential drugs in osteoarthritis	24
SIRT6 inhibits endoplasmic reticulum stress-mediated ferroptosis by activating Nrf2/HO-1 signaling to alleviate osteoarthritis	24
Alleviated NCOA4-mediated ferritinophagy protected RA FLSs from ferroptosis in lipopolysaccharide-induced inflammation under hypoxia	23
SS-31 inhibits mtDNA–cGAS–STING signaling to improve POCD by activating mitophagy in aged mice	23
Systemic inflammation, neuroinflammation and perioperative neurocognitive disorders	23
Targeting JAK/STAT signaling pathways in treatment of inflammatory bowel disease	23
Prolonged effects of DPP-4 inhibitors on steato-hepatitic changes in Sprague–Dawley rats fed a high-cholesterol diet	22
Roquin-1 interaction with Regnase-1 inhibits the progression of rheumatoid arthritis via suppressing FGF2 expression and NF-κB pathway	22
Human antimicrobial/host defense peptide LL-37 may prevent the spread of a local infection through multiple mechanisms: an update	22
Characterization of immune landscape and development of a novel N7-methylguanine-related gene signature to aid therapy in recurrent aphthous stomatitis	22
Treatment with lipoxin A4 improves influenza A infection outcome, induces macrophage reprogramming, anti-inflammatory and pro-resolutive responses	22
Inflammation, coagulation, and cellular injury in heat-induced shock	22
Inflammatory cell death PANoptosis is induced by the anti-cancer curaxin CBL0137 via eliciting the assembly of ZBP1-associated PANoptosome	21
Retraction Note: Knockdown of long non‑coding RNA TUG1 depresses apoptosis of hippocampal neurons in Alzheimer’s disease by elevating microRNA‑15a and repressing ROCK1 expression	21
Granulocyte macrophage colony stimulating factor exerts dominant effects over macrophage colony stimulating factor during macrophage differentiation in vitro to induce an inflammatory phenotype	20
The combination of metabolic syndrome and inflammation increased the risk of colorectal cancer	20
Identification of inflammatory protein biomarkers for predicting the different subtype of adult with tuberculosis: an Olink proteomic study	20
Prospective study of an adalimumab combined with partial enteral nutrition in the induction period of Crohn’s disease	20
Genetic correlations, shared risk genes and immunity landscapes between COVID-19 and venous thromboembolism: evidence from GWAS and bulk transcriptome data	19
Mechanisms of COVID-19-induced kidney injury and current pharmacotherapies	19
Exocytic machineries differentially control mediator release from allergen-triggered RBL-2H3 cells	19
Commentaries: Lecanemab: pioneering the way as the first approved drug for Alzheimer’s disease treatment	18
Inflammatory biomarkers on an LPS-induced RAW 264.7 cell model: a systematic review and meta-analysis	18
The role of regulatory T cells in vitiligo and therapeutic advances: a mini-review	18
USP10 regulates macrophage inflammation responses via stabilizing NEMO in LPS-induced sepsis	18
Characterizing the kinetics of presepsin and associated inflammatory biomarkers in human endotoxemia	18
The star target in SLE: IL-17	17
The molecular mechanisms of remodeling in asthma, COPD and IPF with a special emphasis on the complex role of Wnt5A	17
Single-cell transcriptome analysis of the mouse lungs during the injury and recovery periods after lipopolysaccharide administration	16
Chronic ethanol exposure decreases H3K27me3 in the Il6 promoter region of macrophages and generates persistent dysfunction on neutrophils during fungal infection	16

Modulation of Plet1 expression by N-Acetylglucosamine through the IL-17 A-MAPK pathway in an imiquimod-induced psoriasis mouse model	16
SRY-related high-mobility group box 9 (SOX9) alleviates cigarette smoke extract (CSE)-induced inflammatory injury in human bronchial epithelial cells by suppressing stromal interaction molecule 1 (STI	16
Molecular biology of the novel anticancer medications: a focus on kinases inhibitors, biologics and CAR T-cell therapy	16
Selective inhibition of PKR by C16 accelerates diabetic wound healing by inhibiting NALP3 expression in mice	16
IL-35 modulates Tfh2 and Tfr cell balance to alleviate allergic rhinitis	16
Salidroside alleviates cadmium-induced toxicity in mice by restoring the notch/HES-1 and RIP1-driven inflammatory signaling axis	16
Minocycline alleviates microglia ferroptosis by inhibiting HO-1 during cerebral ischemia–reperfusion injury	15
STAT1-mediated induction of Ly6c-expressing macrophages are involved in the pathogenesis of an acute colitis model	15
COVID-19 pandemic: the delta variant, T-cell responses, and the efficacy of developing vaccines	15
IL-35 promotes IL-35+IL-10+ Bregs and Conventional LAG3+ Tregs in the lung tissue of OVA-Induced Asthmatic Mice	15
CD8 + T cell-based molecular subtypes with heterogeneous immune landscapes and clinical significance in acute myeloid leukemia	15
Interlukin-23 inhibitors as an induction and maintenance therapy for moderate to severe ulcerative colitis: a systematic review and meta‑analysis of randomized controlled trials	15
Enhancing effect of sodium butyrate on phosphatidylserine–liposome-induced macrophage polarization	15
5-oxoETE promote thrombosis in antiphospholipid syndrome by triggering NETs formation through PLC/PKC/ERK pathway	14
The combination of machine learning and untargeted metabolomics identifies the lipid metabolism -related gene CH25H as a potential biomarker in asthma	14
Correction to: Fructose malabsorption in ChREBP-deficient mice disrupts the small intestine immune microenvironment and leads to diarrhea-dominant bowel habit changes	14
Retraction Note: Emerging protective roles of shengmai injection in septic cardiomyopathy in mice by inducing myocardial mitochondrial autophagy via caspase-3/Beclin-1 axis	14
Environmental and inflammatory factors influencing concurrent gut and lung inflammation	14
Challenges and opportunities in inflammatory bowel disease: from current therapeutic strategies to organoid-based models	14
Prostacyclin synthase deficiency exacerbates systemic inflammatory responses in lipopolysaccharide-induced septic shock in mice	14
The clinical trajectory of peripheral blood immune cell subsets, T-cell activation, and cytokines in septic patients	14
Influence of homocysteine on regulating immunothrombosis: mechanisms and therapeutic potential in management of infections	14
Monogenic autoinflammatory disease-associated cardiac damage	14
Altered vacuole membrane protein 1 (VMP1) expression is associated with increased NLRP3 inflammasome activation and mitochondrial dysfunction	14
Evolution of β-catenin-independent Wnt–GSK3–mTOR signalling in regulation of energy metabolism in isoproterenol-induced cardiotoxicity model	13
Association of systemic immune-inflammation index and systemic inflammation response index with chronic kidney disease: observational study of 40,937 adults	13
Exploring macrophage and nerve interaction in endometriosis-associated pain: the inductive role of IL-33	13
Bladder mesenchymal stromal cell-derived exosomal miRNA-217 modulates bladder cancer cell survival through Hippo-YAP pathway	13
Multimodal data-driven prognostic model for predicting new-onset ST-elevation myocardial infarction following emergency percutaneous coronary intervention	13
Causal associations of circulating Helicobacter pylori antibodies with stroke and the mediating role of inflammation	13
Salmonella spvC gene suppresses macrophage/neutrophil antibacterial defense mediated by gasdermin D	13
Bone marrow mesenchymal stem cells-derived exosomes containing miR-539-5p inhibit pyroptosis through NLRP3/caspase-1 signalling to alleviate inflammatory bowel disease	13
GCH1 reduces LPS-induced alveolar macrophage polarization and inflammation by inhibition of ferroptosis	13
Recognition of Mycobacterium tuberculosis by macrophage Toll-like receptor and its role in autophagy	12
Plant extracts and omega-3 supplementation modulate hippocampal oxylipin profile in response to LPS-induced neuroinflammation	12
Retraction Note to: Suppressors of cytokine signalling (SOCS)‑1 inhibits neuroinflammation by regulating ROS and TLR4 in BV2 cells	12
Vitamin D3 suppresses NLRP3 inflammasome pathway and enhances steroid sensitivity in a neutrophilic steroid hyporesponsive asthma mouse model	12
Long-COVID fatigue is not predicted by pre-pandemic plasma IL-6 levels in mild COVID-19	12
Bioinformatics analysis for identifying micro-RNAs, long noncoding RNAs, transcription factors, and immune genes regulatory networks in diabetic cardiomyopathy using an integrated bioinformatics analy	12
Targeting ACE2 as a potential prophylactic strategy against COVID-19-induced exacerbation of chronic kidney disease	12
Transcriptomic analysis reveals molecular characterization and immune landscape of PANoptosis-related genes in atherosclerosis	12
Comprehensive analysis of single cell and bulk RNA sequencing reveals the heterogeneity of melanoma tumor microenvironment and predicts the response of immunotherapy	12
Lipoxin alleviates oxidative stress: a state-of-the-art review	12
Immunopathogenesis of urticaria: a clinical perspective on histamine and cytokine involvement	12
Rhein-attenuates LPS-induced acute lung injury via targeting NFATc1/Trem2 axis	12
STING deficiency protects against wasp venom-induced acute kidney injury	12
The potential roles of Th17 cells in the pathogenesis of oral lichen planus	12
Decoy oligonucleotides targeting NF-κB: a promising therapeutic approach for inflammatory diseases	12
Mediation of macrophage M1 polarization dynamics change by ubiquitin-autophagy-pathway regulated NLRP3 inflammasomes in PD-1 inhibitor-related myocardial inflammatory injury	12
Histamine research advancements in the second year of the COVID-19 pandemic: report of the European Histamine Research Society (EHRS)	12
Annexin A1 (Ac2-26)-dependent Fpr2 receptor alleviates sepsis-induced acute kidney injury by inhibiting inflammation and apoptosis in vivo and in vitro	12
The causal effect of natural killer cells on COVID-19 infection, hospitalization and severity	12
Serine metabolism in macrophage polarization	11
Pentoxifylline in COVID-19 and considerations for its research in long COVID	11
Causal role of myeloid cells in Parkinson’s disease: Mendelian randomization study	11
Calycosin inhibited MIF-mediated inflammatory chemotaxis of macrophages to ameliorate ischemia reperfusion-induced acute kidney injury	11
Simultaneously blocking ANGPTL3 and IL-1β for the treatment of atherosclerosis through lipid-lowering and anti-inflammation	11
The IL-6 autocrine loop promoting IFN-γ-induced fibroblast senescence is involved in psychological stress-mediated exacerbation of vitiligo	11
ADAM10-a “multitasker” in sepsis: focus on its posttranslational target	11
Diamine oxidase knockout mice are not hypersensitive to orally or subcutaneously administered histamine	11
An antagonist of growth hormone-releasing hormone protects against LPS-induced increase of bronchoalveolar lavage fluid protein concentration	11
Agomir miRNA-150-5p alleviates pristane-induced lupus by suppressing myeloid dendritic cells activation and inflammation via TREM-1 axis	11
Screening inflammatory protein biomarkers on premature infants with necrotizing enterocolitis	11
The role of Pim-1 kinases in inflammatory signaling pathways	10
5-Methoxytryptophan ameliorates endotoxin-induced acute lung injury in vivo and in vitro by inhibiting NLRP3 inflammasome-mediated pyroptosis through the Nrf2/HO-1 signaling pathway	10
Crosstalk between N6-methyladenosine modification and ncRNAs in rheumatic diseases: therapeutic and diagnostic implications	10
The RNA-binding protein SND1 promotes the degradation of GPX4 by destabilizing the HSPA5 mRNA and suppressing HSPA5 expression, promoting ferroptosis in osteoarthritis chondrocytes	10
Alpha-galactosylceramide pre-treatment attenuates clinical symptoms of LPS-induced acute neuroinflammation by converting pathogenic iNKT cells to anti-inflammatory iNKT10 cells in the brain	10
The purinergic signalling and inflammation in the pathogenesis and progression of diabetes: key factors and therapeutic targets	10
Insulin/IGF-1 signaling promotes immunosuppression via the STAT3 pathway: impact on the aging process and age-related diseases	10
Cuproptosis-related gene CDKN2A as a molecular target for IPF diagnosis and therapeutics	10
Group 2 innate lymphoid cells derived IL-9 reduces macrophage apoptosis and attenuates acute lung injury in sepsis	10
Inhibition of PRMT6 reduces neomycin-induced inner ear hair cell injury through the restraint of FoxG1 arginine methylation	10
Lipopolysaccharide induces retention of E-cadherin in the endoplasmic reticulum and promotes hybrid epithelial-to-mesenchymal transition of human embryonic stem cells-derived expandable lung epithelia	10
The role of celastrol in inflammation and diseases	10
FK506 impairs neutrophil migration that results in increased polymicrobial sepsis susceptibility	10
The role of IL-1 family of cytokines and receptors in pathogenesis of COVID-19	10
Editorial expression of concern: Monocytes and lymphocytes as active participants in the pathogenesis of experimental shock	10
Transgenic mice overexpressing human ALOX15 under the control of the aP2 promoter are partly protected in the complete Freund’s adjuvant-induced paw inflammation model	10
Wogonin inhibits tight junction disruption via suppression of inflammatory response and phosphorylation of AKT/NF-κB and ERK1/2 in rhinovirus-infected human nasal epithelial cells	10

Homer1 ameliorates ischemic stroke by inhibiting necroptosis-induced neuronal damage and neuroinflammation	10
Therapeutic implications of cyclooxygenase (COX) inhibitors in ischemic injury	10
PI3Kγ controls IL-17A expression and attenuates alveolar bone loss in an experimental periodontitis model	10
Exosomal PPARγ derived from macrophages suppresses LPS-induced peritonitis by negative regulation of CD14/TLR4 axis	10