OOIR: Observatory of International Research

Papers

(The TQCC of Journal of Asian Natural Products Research is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
Prenylated C ₆ –C ₃ derivatives from the root of Illicium ternstroemioides with antiviral activity	89
Secondary metabolites with anti-inflammatory activity isolated from a marine-derived fungus Biscogniauxia sp. 8703	33
A new pyrrolopyrazine alkaloid from the fruit of Lycium chinense	14
Bioactivity-guided isolation of benzocoumarin and quinonoid compounds from Rubia schumanniana and their anti-inflammatory activity in	13
Sesquilignans PD from Zanthoxylum nitidum var. tomentosum exerts antitumor effects via the ROS/MAPK pathway	11
Novel antimicrobial defensin peptides from different coleopteran insects (Coleoptera: Insecta): identification, characterisation and antimicrobial properties	11
An efficient method for identifying natural common homoisoflavonoid by¹H-NMR	10
Targeting epithelial-mesenchymal transition: breviscapine, a promising natural product in cancer and organ fibrosis treatment	10
Sesquiterpenes from Wikstroemia lungtzeensis with anti-neuroinflammatory effects	10
A new canthinone glycoside isolated from the root barks of Ailanthus altissima with NO inhibitory activity	9
Two new guaianolide-type sesquiterpenoids with NO inhibitory activity from Chrysanthemum indicum	9
Synthesis of 19-hydroxyprogesterone and insights into the ring-opening mechanism of the 6,19-epoxy bridge	9
Cyclic hexadepsipeptides from the fermentation of Fusarium sp. DCJ-A and their cytotoxic activities	8
Chemical constituents from the fibrous roots of Anemarrhena asphodeloides and their in vitro cytotoxic act	8
Comparative pharmacokinetic studies on ginsenosides in the common and ultrafine granular powder of Panax ginseng by using UHPLC-MS/MS	8
Three new pyridine alkaloids and one new iridoid analogue from the leaves of Rehmannia glutinosa	8
Synthesis and biological activity of the marine-derived leonurine analogue N-(4-guanidinobutyl)-2-(4-hydroxyphenyl)-2-oxoacetamide	8
Evaluation of therapeutic role of harmaline: in vitro cytotoxicity targeting nucleic acids	7
Exploring the mechanism of daphne-type diterpenes against gastric cancer cells	7
Bis-piperidine alkaloids from the peels of Areca catechu	7
Two new chemical constituents from the stem and branch of Tripterygium wilfordii	7
Caenorhabditis elegans as in vivo model for the screening of natural plants-derived novel anti-aging compounds: a short introduction	7
New caffeoyl derivatives with potent DPPH radical scavenging activity from Elephantopus tomentosus	7
An integrative strategy for comprehensive determination of nineteen constituents from Eupatorii Herba and application in pharmacokinetic study by combing	6
Two new abietane diterpenoids from Pinus massoniana	6

Chemical constituents of the marine-derived fungus Acremonium sp. AN-13	6
Atramacronoid A induces the PANoptosis-like cell death of human breast cancer cells through the CASP-3/PARP-GSDMD-MLKL pathways	6
Resveratrol affects proliferation, apoptosis and migration of fibroblast cells as well as inhibits COL1A1/2 and TGFB2/3 gene expression	6
Hepatoprotective iridoid glycosides from the aerial parts of Paederia foetida	6
Secondary metabolites from the fungus Cladosporium xylophilum	6
Potential benefits of marine-derived compounds for slowing the advancement of Alzheimer’s disease	6
Integrated ceRNAs regulating relationship and bioinformatics analysis to study the molecular mechanisms of the inhibition of puerarin on bladder cancer cell	6
Enhancement of aqueous solubility of hesperidin and naringenin utilizing hydrotropic solubilization technique: characterization and in vitro evaluation	6
Regulation of Fuzheng Huayu capsule on inhibiting the fibrosis-associated hepatocellular carcinogenesis	6
A new flavonolignan from milk thistle ( Silybum marianum )	6
Design, synthesis and anti-tumor activity of asiatic acid derivatives as VEGF inhibitors	6
Precision modulation of the gut microbiota-immune axis by natural products: a structure-activity relationship perspective in cancer immunotherapy	5
Resveratrol: a potential alternative therapeutic agent for patients suffering from chronic obstructive pulmonary disease (COPD)	5
Two highly conjugated ergosterols from the fungus Psathyrella rogueiana and their anti-inflammatory activity	5
Hyrtiosins F and G, two new scalarane sesterterpenes from the South China sea sponge Hyrtios erecta	5
A new terrein dimer and a new meroterpene from the mangrove endophytic fungus Lichtheimia sp.	5
Saikosaponin D, a triterpene saponin from Bupleurum falcatum , restores circadian rhythm and attenuates hepatic fibrosis via Esr1-Per2 axis	5
Osthole, an ingredient fromCnidium monnieri, reduces the pyroptosis and apoptosis in bronchial epithelial cells	5
Survey of natural products reported by Asian research groups in 2023	5
The basic chemical substances of total alkaloids of Uncaria rhynchophylla and their anti-neuroinflammatory activities	5
Pseudoamaolide P, a 1,2:3,4:9,10:9,19-tetraseco-cycloartane triterpene spiroketal lactone from seeds of Pseudolarix amabilis	5
Moldavica acid A, a new salicylic acid derivative from Dracocephalum moldavica	5
Total synthesis of albafuran B and its osteogenic differentiation promoting effect on human mesenchymal stem cells	5
Harmine inhibits the proliferation and migration and promotes the apoptosis of colon cancer cells via inhibition of the FAK/AKT and ERK _1/2 /CREB signaling pathways	5
Astragaloside IV targeting autophagy of T cells improves inflammation of asthma	5
Antitumor effects of BPCO on liver cancer cells	5
Polyprenylated acylphloroglucinols from Hypericum sampsonii with cytotoxicity against pancreatic carcinomas	5
Two new compounds from Pergularia tomentosa growing wildly in Jordan	5
Two new baccharane triterpenes isolated from Rhus chinensis	5
Screening of GLP-1r agonists from natural products using affinity ultrafiltration screening coupled with UPLC-ESI-Orbitrap-MS technology: a case study of Panax ginseng	5
Labdane- type diterpenoids and sesquiterpenes from Curcuma aromatica and their nitric oxide inhibitory activity in lipopolysaccharide-stim	5
Characterization of metabolic profile of Dazhu Hongjingtian and evaluation of its anti-hypoxic constituents	4
Two new dihydro-β-agarofuran sesquiterpenes from the roots of Celastrus angulatus	4
Design, synthesis, and anti-oomycete activity of 3-acyloxymaltol/ethyl maltol derivatives	4
Chemical constituents from the leaves and branches of Wikstroemia chamaedaphne with their activation of latent HIV activities	4
Synthesis of scaberol C amino acid ester derivatives with anti-cancer activity	4
New modified silybin derivatives: design, synthesis, and preliminary evaluation of antitumor activity	4
Expanding the role of alpha lipoic acid for psychiatric and neurological health	4
Special issue commemorating the 40th anniversary of the College of Traditional Chinese Medicine, Shenyang Pharmaceutical University	4
Regulatory effect of isovitexin on MAPK/NF-κB signal in mice with acute ulcerative colitis	4
Dihydrophenanthro[ b ]furan derivatives from the tubers of Bletilla striata	4
Synthesis and antitumor activity of erysolin and its metabolites	4
Two new compounds from the green walnut husks of Juglans mandshurica	4
Cytotoxic ent -abietane diterpenoids from the leaves of Croton crassifolius	4
Design, synthesis and antitumor activity of pentacyclic triterpenoid ursolic acid derivatives and oleanolic acid derivatives based on multi-target	4
11 α -hydroxydysobinin: a new limonoid from Chisocheton macrophyllus seeds (Meliaceae)	4
Cytotoxic nortriterpenoids from the barks of Juglans cathayensis	4
Hyperwightianols I-N, six new meroterpenoids from Hypericum wightianum	4
The changes of intestinal microbiota and metabolomics during the inhibition of bladder cancer by liquiritigenin	4
A new resorcylic acid lactone from the endophytic fungus Chaetosphaeronema sp.	4

Macrophorins H and L, two new HMG-conjugate macrophorins from rihzospheric Penicillium sp. NX-05-G-3	4
Quantitative predictive model for screening optimal processing methods of Polygonati rhizoma	4
Simultaneous assessment of absorption and pharmacokinetic characteristics of four active flavonoids from Chimonanthus nitens Leaf Granules using LC-MS determination: in vivo	4
A novel pyrrolidine alkaloid and a novel isoflavone with anti-inflammatory activity from the tubers of Arisaema franchetianum	4
Diverse neolignans and lignans from an aqueous extract of the Angelica sinensis root head	4
Genome mining guided discovery of new pentangular polyketides from the marine rare actinomycete Actinoalloteichus hymeniacidonis DSM 45092	4
Two new triterpenoid saponins from the underground parts of Weigela x “Bristol Ruby”	4
Lignans from the root of Valeriana jatamansi and their biological evaluation	4
Prenylated flavones with potential antiproliferative activities from the stems and leaves of Mycetia hainanensis	4
Network pharmacology analysis and experimental validation of Yinma Jiedu Granule in the treatment of acute pharyngitis	4
Survey of natural products reported by Asian research groups in 2024	4
Simultaneous determination of nine compounds from the roots of Euphorbia fischeriana , Euphorbia ebracteolata and Stellera	4
Phenylpropanoids from Sparganium stoloniferum and their antiplatelet aggregation activities	3
A new alkaloid from Thespesia populnea endophytic fungus Penicillium sp. TM-Y1-1	3
Shaoyao-Gancao decoction improves dyslipidemia in rats with polycystic ovary syndrome by reshaping the gut microbiota and regulating the bile acid/FXR pathway	3
Biotransformation and activity identification of icariin in human intestinal fungus Pichia occidentalis	3
Study on the anti-HBV activity of matrine alkaloids from Oxytropis ochrocephala by MTT, 3d-QSAR, molecular docking and molecular dynamics simulation	3
Effects of bergapten-loaded long-circulating liposomes on osteogenic differentiation of human dental pulp stem cells	3
Synthesis and evaluation of L-quebrachitol derivatives against platelet aggregation	3
Two new glycosides and a new flavone from Gerbera delavayi	3
Network pharmacology approach and experimental verification of Manzufei decoction in the treatment of chronic obstructive pulmonary disease	3
Characterization and antimicrobial evaluation of anthraquinones and triterpenes from Rubia cordifolia	3
Synthesis and biological evaluation of asiatic acid derivatives as c-Kit inhibitors	3
Three new quinolizidine alkaloids from the roots of Sophora tonkinensis	3
New sesquiterpenoids from Biscogniauxia sp.	3
Recent advances in natural products and derivatives with antiviral activity against respiratory syncytial virus (RSV)	3
A new steroid from Penicillium brocae G2131	3
Ursolic acid triterpenoids in Salvia rosmarinus with potent anti-inflammatory activity	3
Evaluation of the potential anti-arthritic effects and evaluation of acute oral toxicity of the active fraction of Eclipta prostrata leaves in rat model	3
Synthesis and antibacterial activity of naringenin derivatives containing selenocyanate moiety	3
New α -glucosidase inhibitory isoflavone derivatives from the leaves of Placolobium vietnamense	3
Reno-protective mechanisms of curcumin in diabetic nephropathy	3
Glutinol, main component of orostachys japonica , inhibits in vitro and in vivo TGF-β-induced epithelial m	3
Cordycepin, a bioactive compound from Cordyceps spp ., moderates Alzheimer’s disease-associated pathology via anti-oxidative stress and autophagy activation	3
Flavonoids as potential KRAS inhibitors: DFT, molecular docking, molecular dynamics simulation and ADMET analyses	3
Unlocking the potential of Radix Astragali and its active ingredients in gastric ulcer therapy	3
New polyketides from the basidiomycetous fungusPholiotasp.	3
Genome mining for ribosomally synthesized and post-translationally modified peptides (RiPPs) in Streptomyces bacteria	3
Design, synthesis and biological activity of oxyevodiamine-based histone deacetylase 6 inhibitors	3
Coumarins and flavones with anti-inflammatory activity isolated from the branches and leaves of Daphne retusa	3
Characterization of the metabolic contributions of cytochrome P450 isoforms to bicyclol using the relative activity factor method	3
Pachyphyllanone, a new cycloartane triterpenoid isolated from Aglaia pachyphylla and its cytotoxic activity	3
Exploring sulphated polysaccharides from marine bivalves: Unveiling potent anti-gastric cancer activity through cell cycle arrest and apoptosis	3
Three new flavonoids from the roots of Sophora tonkinensis	3
Three new terpenoid derivatives from the deep-sea-derived fungus Aspergillus sydowii DFFSCS007	3
Xanthonolignoids from Hypericum curvisepalum with quorum sensing inhibitory activity against Chromobacterium violaceum	3
Ginseng: a traditional medicine and food homologous plant	3
Two new tetralones from the endophytic fungus Annulohypoxylon stygium A888	3
Progress in the study of curcumin metabolism in vivo	3
Four new tirucallane-type triterpenoids from Aphanamixis polystachya	3
Leptols A and B, one meroterpenoid and one coumarin hybrid from the leaves of Melicope pteleifolia and its anti-inflammation in BV2 cells	3
Cytotoxic iridoid glycosides from the leaves of Paederia scandens	3
Oral health promotion of flavonoids from Scutellaria baicalensis	3
Triterpenoids from Juglans sigillata and their anti-inflammatory and radical scavenging activity	3
Acetylcholinesterase inhibition studies of alkaloid components from Crinum asiaticum var. sinicum :	3
Isolation of a new steroid from phytochemical investigation on Caralluma lasiantha	3
Design, synthesis and anti-tumor activity of oleanolic acid derivatives targeting EGFR	3
Cytotoxic limonoids from the barks of Chisocheton siamensis	3
Are phenolic compounds produced during the enzymatic production of prebiotic xylooligosaccharides (XOS) beneficial: a review	3
Analysis of intestinal bacterial carboxylesterase-mediated metabolites and the potential antitumour molecular mechanism of angoroside C	3
Genistein resists castration-resistant prostate cancer by inhibiting the androgen receptor pathway	3
Two new bergamotane-type sesquiterpeniods from the plant endophytic fungus Paraconiothyrium brasiliense	3
Discovery of two new long chain fatty acid esters of flavonol glycoside from Pollen Typhae Carbonisatus and their protective effects on HBMECs	3
Correlation analysis between potential hepatotoxicity and ingredient content of polygoni multiflori caulis	3
Phloroglucinol derivatives with α- glucosidase inhibitory activities from Syzygium fluviatile	3
In vivo antiulcerogenic effect of morinda elliptica stem extract against ethanol-induced gastric ulcer in rat	3
Effect and mechanism of gomisin D on the isoproterenol induced myocardial injury in H9C2 cells and mice	3
Two new alkaloids produced by Dothideomycetes sp. BMC-101 isolated from the Magnolia grandiflora	3
A new nor-28-oleanane glycoside isolated from Syzygium formosum inhibits nitric oxide production in LPS-stimulated RAW264.7 cells	3
Ecdysteroid-enriched fraction of Cyathula officinalis suppresses synovial proliferation and inflammation to ameliorate RA by inhibiting the AKT/PI3K/mTOR	3
(+)- and (-)-Tedanine, a pair of new enantiomeric indolone alkaloids from the marine sponge Tedania sp.	3
Exploration and computational assessment of ochrocephalamine G from Oxytropis ochrocephala as an anti-HBV candidate	3
Carnosol attenuates high glucose damage in human retinal endothelial cells through regulation of ERK/Nrf2/HO-1 pathway	3
Preclinical determination of wound-healing activity of halibut oil cream in rat model of burn wound	3
Eriodictyol inhibits the proliferation and inflammatory response in keratinocytes in psoriasis through inactivating DYRK1A-mediated endoplasmic reticulum stress	3
Sulfonated and sulfated lignans/neolignans from an aqueous extract of Isatis indigotica roots	3
Chlorogenic acid targets SLC37A2 to inhibit macrophage activation via ER-dependent NF-κB and NLRP3 signaling pathways against sepsis-induced acute lung injury	3
Discovery of sesquiterpene lactones with anti-inflammatory effect from Youngia japonica	3