American Journal of Physiology-Lung Cellular and Molecular Physiology

Papers
(The median citation count of American Journal of Physiology-Lung Cellular and Molecular Physiology is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)
ArticleCitations
Simple model of pulmonary hypertension secondary to left heart pressure overload induced by partial intravascular occlusion of the ascending aorta100
Feeling good: welcoming the new editorial team for American Journal of Physiology-Lung Cellular and Molecular Physiology89
Diacylglycerol kinase is a keystone regulator of signaling relevant to the pathophysiology of asthma54
ARDS in the time of corona: context and perspective51
Diet-induced obesity worsens allergen-induced type 2/type 17 inflammation in airways by enhancing DUOX1 activation46
Genes, other than Muc5b, play a role in bleomycin-induced lung fibrosis42
PTPα promotes fibroproliferative responses after acute lung injury40
Metabolic signatures of ARDS and ARDS heterogeneity37
Early extubation to noninvasive respiratory support of former preterm lambs improves long-term respiratory outcomes34
Oxidized phosphatidylcholines induce multiple functional defects in airway epithelial cells32
Rat bronchoalveolar lavage proteome changes following e-cigarette aerosol exposures32
FGF18 promotes human lung branching morphogenesis through regulating mesenchymal progenitor cells32
COPD susceptibility gene HHIP regulates repair genes in airway epithelial cells and repair within the epithelial-mesenchymal trophic unit31
A preclinical systematic review and meta-analysis assessing the effect of biological sex in lipopolysaccharide-induced acute lung injury31
A personal appreciation of Mary Ellen Avery for World Prematurity Day30
Reply to Vogel et al.28
Endothelial knockdown of the tumor suppressor, WWOX, increases inflammation in ventilator-induced lung injury27
Increased exploration and hyperlocomotion in a cigarette smoke and LPS-induced murine model of COPD: linking pulmonary and systemic inflammation with the brain26
A proinflammatory long noncoding RNA Lncenc1 regulates inflammasome activation in macrophage26
Muc5b plays a role in the development of inflammation and fibrosis in hypersensitivity pneumonitis induced bySaccharopolyspora rectivirgula26
PINK1 mediates the protective effects of thyroid hormone T3 in hyperoxia-induced lung injury25
Electronic cigarette exposure disrupts airway epithelial barrier function and exacerbates viral infection25
The lung extracellular matrix protein landscape in severe early-onset and moderate chronic obstructive pulmonary disease24
Mechanosensitive channel Piezo1 is required for pulmonary artery smooth muscle cell proliferation24
Lung disease manifestations in Down syndrome23
Dynamic driving pressure predicts ventilator-induced lung injury in mice with and without endotoxin-induced acute lung injury23
Role of STIM1 in stretch-induced signaling in human airway smooth muscle23
CFTR as a therapeutic target for severe lung infection23
Biomarkers of alveolar epithelial injury and endothelial dysfunction are associated with scores of pulmonary edema in invasively ventilated patients23
Exhaled breath condensate identifies metabolic dysregulation in patients with radiation-induced lung injury22
Dysregulation of ion transport in the lung epithelium infected with SARS-CoV-222
Activation of platelets and the complement system in mice with Schistosoma-induced pulmonary hypertension22
Cross talk between LAM cells and fibroblasts may influence alveolar epithelial cell behavior in lymphangioleiomyomatosis22
Contribution of fatty acid oxidation to the pathogenesis of pulmonary hypertension21
β-Ionone facilitates ex vivo airway smooth muscle relaxation via extraocular opsin-3 light receptor activation21
Passive siRNA transfection method for gene knockdown in air-liquid interface airway epithelial cell cultures21
Role of transient receptor potential vanilloid 4 in therapeutic antifibrotic effects of pirfenidone21
Integral assessment of gas exchange during veno-arterial ECMO: accuracy and precision of a modified Fick principle in a porcine model21
FGF2 is secreted in extracellular vesicles from lung cells21
Increased serum SP-D in identification of high-risk smokers at high risk of COPD20
Role of voltage-gated Ca2+ channels and Ano1 Ca2+-activated Cl channels in M2 muscarinic receptor-dependent contractions of murine airway smooth muscle20
Effects of glial-derived neurotrophic factor on remodeling and mitochondrial function in human airway smooth muscle cells20
Inflammatory and antiviral responses to influenza A virus infection are dysregulated in pregnant mice with allergic airway disease20
Nicotinic receptors in airway disease19
IL-17A neutralization fails to attenuate airway remodeling and potentiates a proinflammatory lung microenvironment in diacetyl-exposed rats19
Call for Papers: “Alveolar biology, pulmonary surfactant, and beyond”: a tribute to Dr. John Allen Clements on his 100th birthday19
An American Physiological Society cross-journal Call for Papers on “Inter-Organ Communication in Homeostasis and Disease”19
A comprehensive map of proteoglycan expression and deposition in the pulmonary arterial wall in health and pulmonary hypertension19
Endothelin-1 depletion of cartilage oligomeric matrix protein modulates pulmonary artery superoxide and iron metabolism-associated mitochondrial heme biosynthesis19
T-cell dysregulation and inflammatory process in Gcn2 (Eif2ak4−/−)-deficient rats in basal and stress conditions19
Systematic analysis of candidate reference genes for gene expression analysis in hyperoxia-based mouse models of bronchopulmonary dysplasia18
A rapidly changing understanding of COPD: World COPD Day from the COPD Foundation18
Cellular senescence is increased in airway smooth muscle cells of elderly persons with asthma18
The effect of adrenalectomy on bleomycin-induced pulmonary fibrosis in mice18
Abrogation of mesenchyme-specific TGF-β signaling results in lung malformation with prenatal pulmonary cysts in mice18
ADAM10 partially protects mice against influenza pneumonia by suppressing specific myeloid cell population17
Cross-journal Call for Papers on “Opioids and Respiratory Depression”17
Epinephrine evokes shortening of human airway smooth muscle cells following β2adrenergic receptor desensitization17
SM22α cell-specific HIF stabilization mitigates hyperoxia-induced neonatal lung injury17
Circulating biomarker analyses in a longitudinal cohort of patients with IPF17
Surfactant Protein-A and its immunomodulatory roles in infant respiratory syncytial virus infection: a potential for therapeutic intervention?17
World health day observances in November 2021: advocating for adult and pediatric pneumonia, preterm birth, and chronic obstructive pulmonary disease17
Good things: announcing the next round of the American Journal of Physiology-Lung Cellular and Molecular Physiology Editorial Board Fellowship Program17
Effect of physical activity in lymphocytes senescence burden in patients with COPD17
M4 muscarinic receptors mediate acetylcholine-induced suppressant effects on the cough reflex in the caudal nucleus tractus solitarii of the rabbit17
Development of a peripheral blood transcriptomic gene signature to predict bronchopulmonary dysplasia16
A new Anticalin protein for IL-23 inhibits non-type 2 allergen-driven mouse lung inflammation and airway hyperresponsiveness16
Pharmacological sphingosine-1 phosphate receptor 1 targeting in cigarette smoke-induced emphysema in mice16
Mouse lung organoid responses to reduced, increased, and cyclic stretch16
Role of ZIP kinase in development of myofibroblast differentiation from HPMCs16
BMP4 and Wnt signaling interact to promote mouse tracheal mesenchyme morphogenesis16
Mitochondrial ribosomal stress in lung diseases16
Living with lung disease: experimental models to assess the long-term effects of prematurity16
Pulmonary implications of acetaminophen exposures independent of hepatic toxicity16
Acute vaping in a golden Syrian hamster causes inflammatory response transcriptomic changes15
Short-chain fatty acids improve inflamm-aging and acute lung injury in old mice15
World AIDS Day 2021: highlighting the pulmonary complications of HIV/AIDS15
Changes in intestinal homeostasis and immunity in a cigarette smoke- and LPS-induced murine model for COPD: the lung-gut axis15
RSV attenuates epithelial cell restitution by inhibiting actin cytoskeleton-dependent cell migration15
Protective effects of neuropeptide Y against elastase-induced pulmonary emphysema15
Nicotine affects mitochondrial structure and function in human airway smooth muscle cells15
Menthol in electronic cigarettes causes biophysical inhibition of pulmonary surfactant15
Stem cells, cell therapies, and bioengineering in lung biology and disease 202115
Pathogenesis, clinical features of asthma COPD overlap, and therapeutic modalities14
Long-term survivors of murine sepsis are predisposed to enhanced LPS-induced lung injury and proinflammatory immune reprogramming14
Absolute quantification of plasma mitochondrial DNA by droplet digital PCR marks COVID-19 severity over time during intensive care unit admissions14
Culture conditions differentially regulate the inflammatory niche and cellular phenotype of tracheobronchial basal stem cells14
cUMP elicits interendothelial gap formation during Pseudomonas aeruginosa infection14
A pediatric perspective on World Sepsis Day in 2021: leveraging lessons from the pandemic to reduce the global pediatric sepsis burden?14
High-altitude pulmonary edema: the intercellular network hypothesis14
The pontine Kölliker-Fuse nucleus is important for reduced postinspiratory airflow elicited by stimulation of the ventral respiratory parafacial region14
Molecular mechanisms of Na,K-ATPase dysregulation driving alveolar epithelial barrier failure in severe COVID-1914
Contribution of transient receptor potential canonical channels in human and experimental pulmonary arterial hypertension14
A new anesthesia protocol enabling longitudinal lung-function measurements in neonatal rabbits by micro-CT14
Pulmonary-delivered Anticalin Jagged-1 antagonists reduce experimental airway mucus hyperproduction and obstruction14
Every breath you take: exploring macrophages and environmental exposures in the lung—a tribute to Dr. Joseph Brain’s legacy13
Peer Review Week, 202113
A toolbox for studying respiratory viral infections using air-liquid interface cultures of human airway epithelial cells13
A wrinkle in time: circadian biology in pulmonary vascular health and disease13
Targeted stereology: sampling heterogeneously distributed structures and lesions in the lung13
Wnt5a/β-catenin axis is involved in the downregulation of AT2 lineage by PAI-113
Lung-kidney interactions and their role in chronic kidney disease-associated pulmonary diseases13
Distinct types of plexiform lesions identified by synchrotron-based phase-contrast micro-CT13
Exposure to carbon black nanoparticles during pregnancy aggravates lipopolysaccharide-induced lung injury in offspring: an intergenerational effect13
Analysis of the alveolar shape in 3-D13
T cell and airway smooth muscle interaction: a key driver of asthmatic airway inflammation and remodeling13
Understanding the role of placental pathophysiology in the development of bronchopulmonary dysplasia13
Constitutive transgenic α-Klotho overexpression enhances resilience to and recovery from murine acute lung injury13
Endothelial metabolism in pulmonary vascular homeostasis and acute respiratory distress syndrome13
Sensitive physiological readouts to evaluate countermeasures for lipopolysaccharide-induced lung alterations in mice12
Genetic deficiency of the transcription factor NFAT1 confers protection against fibrogenic responses independent of immune influx12
Muscarinic receptors in the nucleus tractus solitarii12
Lysyl oxidase regulation and protein aldehydes in the injured newborn lung12
Maternal diabetes promotes offspring lung dysfunction and inflammation in a sex-dependent manner12
Corrigendum for Audi et al., volume 323, 2022, p. L410–L42212
Reply to Myslivecek12
Impaired antiviral immunity in frequent exacerbators of chronic obstructive pulmonary disease12
Alpha-1 antitrypsin inhibits fractalkine-mediated monocyte-lung endothelial cell interactions12
Diacetyl inhalation impairs airway epithelial repair in mice infected with influenza A virus12
Racing against time: leveraging preclinical models to understand pulmonary susceptibility to perinatal acetaminophen exposures12
Congenital heart disease-associated pulmonary dysplasia and its underlying mechanisms12
RSV infection potentiates TRPV1-mediated calcium transport in bronchial epithelium of asthmatic children12
An rRNA fragment in extracellular vesicles secreted by human airway epithelial cells increases the fluoroquinolone sensitivity of P. aeruginosa11
Antenatal mesenchymal stromal cell extracellular vesicle treatment preserves lung development in a model of bronchopulmonary dysplasia due to chorioamnionitis11
Enhanced epithelial sodium channel activity in neonatal Scnn1b mouse lung attenuates high oxygen-induced lung injury11
Distribution, composition, and activity of airway-associated adipose tissue in the porcine lung11
Complex roles of TGF-β signaling pathways in lung development and bronchopulmonary dysplasia11
Endothelial PHD2 deficiency induces apoptosis resistance and inflammation via AKT activation and AIP1 loss independent of HIF2α11
Human pulmonary microvascular endothelial cell DDAH1-mediated nitric oxide production promotes pulmonary smooth muscle cell apoptosis in co-culture11
LL-37 and HMGB1 induce alveolar damage and reduce lung tissue regeneration via RAGE11
Mitoquinone mesylate attenuates pathological features of lean and obese allergic asthma in mice11
Inference of alveolar capillary network connectivity from blood flow dynamics11
LMTK2 switches on canonical TGF-β1 signaling in human bronchial epithelial cells11
Involvement of ryanodine receptors in the contraction of small pulmonary veins11
MK2 nonenzymatically promotes nuclear translocation of caspase-3 and resultant apoptosis11
The matricellular protein CCN3 supports lung endothelial homeostasis and function11
Prolonged, physiologically relevant nicotine concentrations in the airways of smokers11
Newer insights into the pathobiological and pharmacological basis of the sex disparity in patients with pulmonary arterial hypertension11
Differentiating children with sepsis with and without acute respiratory distress syndrome using proteomics11
Chronic hyperglycemia aggravates lung function in a Scnn1b-Tg murine model11
Geranylgeranyl diphosphate synthase deficiency hyperactivates macrophages and aggravates lipopolysaccharide-induced acute lung injury11
A simple method to generate human airway epithelial organoids with externally orientated apical membranes11
Investigating the role of platelets and platelet-derived transforming growth factor-β in idiopathic pulmonary fibrosis11
Lack of a transcriptional response of primary bronchial epithelial cells from patients with asthma and controls to IL-3311
Lung pericytes as mediators of inflammation11
M2 macrophages have unique transcriptomes but conditioned media does not promote profibrotic responses in lung fibroblasts or alveolar epithelial cells in vitro10
The inflammatory role of dysregulated IRS2 in pulmonary vascular remodeling under hypoxic conditions10
PMN recruitment in inflammatory lung injury models follows classical transendothelial migration paradigms requiring PECAM-1 and CD9910
Stereological analysis of the naked mole-rat Heterocephalus glaber lung provides evidence of altered surfactant function and late alveolarization10
Multicompartmental analysis of the murine pulmonary immune response by spectral flow cytometry10
Enhanced glycolysis causes extracellular acidification and activates acid-sensing ion channel 1a in hypoxic pulmonary hypertension10
Red blood cells function as reservoirs of tumor DNA10
Molecular insights using spatial transcriptomics of the distal lung in congenital diaphragmatic hernia10
Store-operated calcium entry-associated regulatory factor regulates airway inflammation and airway remodeling in asthma mice models10
A proteomics approach to identify COPD-related changes in lung fibroblasts10
Identification of FGFR4 as a regulator of myofibroblast differentiation in pulmonary fibrosis10
The impact of nebulized epoprostenol and iloprost on hemoglobin oxygen affinity: an ex vivo experiment10
Rho/ROCK-MYOCD in regulating airway smooth muscle growth and remodeling10
Obesity elicits a unique metabolomic signature in human airway smooth muscle cells10
Ivacaftor partially corrects airway inflammation in a humanized G551D rat10
Understanding potential mechanisms of harm: the drivers of electronic cigarette-induced changes in alveolar macrophages, neutrophils, and lung epithelial cells10
Single-cell RNA sequencing and binary hierarchical clustering define lung interstitial macrophage heterogeneity in response to hypoxia9
Rapid postmortem ventilation improves donor lung viability by extending the tolerable warm ischemic time after cardiac death in mice9
Optimizing miRNA transfection for screening in precision cut lung slices9
Multivalent, calcium-independent binding of surfactant protein A and D to sulfated glycosaminoglycans of the alveolar epithelial glycocalyx9
GPx3 deficiency exacerbates maladaptive right ventricular remodeling in experimental pulmonary artery banding9
Blocking ATP-releasing channels prevents high extracellular ATP levels and airway hyperreactivity in an asthmatic mouse model9
Human airway lineages derived from pluripotent stem cells reveal the epithelial responses to SARS-CoV-2 infection9
Piezo channels modulate human lung fibroblast function9
One percent of the clinical dose used for antenatal steroid therapy is sufficient to induce lung maturation when administered directly to the preterm ovine fetus9
The differential roles of the two NO-GC isoforms in adjusting airway reactivity9
TRPC6, a therapeutic target for pulmonary hypertension9
Identification of lung innervating sensory neurons and their target specificity9
Dynamic positive end-expiratory pressure strategies using time and pressure recruitment at birth reduce early expression of lung injury in preterm lambs9
Metabolic profiling of in vivo right ventricular function and exercise performance in pulmonary arterial hypertension9
Optimization of long-term cold storage of rat precision-cut lung slices with a tissue preservation solution9
Exposure to the heated tobacco product IQOS generates apoptosis-mediated pulmonary emphysema in murine lungs9
Early-life pulmonary viral infection leads to long-term functional and lower airway structural changes in the lungs9
In vivo molecular imaging stratifies rats with different susceptibilities to hyperoxic acute lung injury9
Increased circulating cytokeratin 19 fragment levels in preterm neonates receiving mechanical ventilation are associated with poor outcome9
Chemokines, soluble PD-L1, and immune cell hyporesponsiveness are distinct features of SARS-CoV-2 critical illness8
p120-Catenin suppresses NLRP3 inflammasome activation in macrophages8
Recombinant human β-defensin 2 delivery improves smoking-induced lung neutrophilia and bacterial exacerbation8
Fungal chitin is not an independent mediator of allergic fungal asthma severity8
The effect of estrogen in coronavirus disease 20198
Biphasic regulation of miR-17∼92 transcription during hypoxia: roles of HIF1 and p53 hyperphosphorylation at ser158
Reply to Gille et al.8
Low global arginine bioavailability: a common phenomenon in pulmonary hypertension8
Loss of prolyl hydroxylase 1 and 2 in SM22α-expressing cells prevents Hypoxia-Induced pulmonary hypertension8
MicroRNA-200b deficiency is not sufficient to increase susceptibility to allergen-induced airway inflammation and dysfunction in mice8
Association of cystic fibrosis transmembrane conductance regulator with epithelial sodium channel subunits carrying Liddle’s syndrome mutations8
Connecting clinical, environmental, and genetic factors point to an essential role for vitamin A signaling in the pathogenesis of congenital diaphragmatic hernia8
Extracellular vesicles secreted by primary human bronchial epithelial cells reduce Pseudomonas aeruginosa burden and inflammation in cystic fibrosis mouse lung8
IL-23 amplifies the epithelial-mesenchymal transition of mechanically conditioned alveolar epithelial cells in rheumatoid arthritis-associated interstitial lung disease through mTOR/S6 signaling8
Characteristics, triggers, treatments, and experimental models of neonatal acute respiratory distress syndrome8
The pH-sensitive translocation of V-ATPase in the small airway of cystic fibrosis pigs8
Intrapulmonary arterial contraction assay reveals region-specific deregulation of vasoreactivity to lung injuries8
Three-dimensional electrical impedance tomography to study regional ventilation/perfusion ratios in anesthetized pigs8
Prenatal vitamin D supplementation mitigates inflammation-related alveolar remodeling in neonatal mice8
Loss of growth differentiation factor 15 exacerbates lung injury in neonatal mice8
Are circulating endothelial cells the next target for transcriptome-level pathway analysis in ARDS?8
Mice with lymphatic dysfunction develop pathogenic lung tertiary lymphoid organs that model an autoimmune emphysema phenotype of COPD8
Diesel exhaust particles induce polarization state-dependent functional and transcriptional changes in human monocyte-derived macrophages7
The mysterious case of missing lymphocytes: a cautionary tale of interinstitutional variability in outcomes of lung dissociation protocols7
Low-dose vanadium pentoxide perturbed lung metabolism associated with inflammation and fibrosis signaling in male animal and in vitro models7
P2X7 signaling influences the production of pro-resolving and pro-inflammatory lipid mediators in alveolar macrophages derived from individuals with asthma7
Elevated IL-15 concentrations in the sarcoidosis lung are independent of granuloma burden and disease phenotypes7
The misuse of respiratory resistive loading during aerobic exercises: revisiting mechanisms of “standalone” inspiratory muscle training7
BATF2 enhances proinflammatory cytokine responses in macrophages and improves early host defense against pulmonary Klebsiella pneumoniae infection7
Pulmonary capillary blood volume and diffusing membrane capacity during exercise in humans: role of pulmonary artery pressure7
Effects of hypoxia on respiratory diseases: perspective view of epithelial ion transport7
Cigarette smoke-induced airspace disease in mice develops independently of HIF-1α signaling in leukocytes7
Effects of maternal edible THC consumption on offspring lung growth and function in a rhesus macaque model7
CFTR function and clinical response to modulators parallel nasal epithelial organoid swelling7
An update in club cell biology and its potential relevance to chronic obstructive pulmonary disease7
Senescence of lung mesenchymal stem cells of preterm infants by cyclic stretch and hyperoxia via p217
Cortactin loss protects against hemin-induced acute lung injury in sickle cell disease7
Comprehensive review of lipocalin 2-mediated effects in lung inflammation7
The oxygen dissociation curve of blood in COVID-197
The highly packed and dehydrated structure of preformed unexposed human pulmonary surfactant isolated from amniotic fluid7
Short palate, lung, and nasal epithelial clone 1 (SPLUNC1) level determines steroid-resistant airway inflammation in aging7
Quantification of smooth muscle in human airways by polarization-sensitive optical coherence tomography requires correction for perichondrium7
Downregulation of protein phosphatase 2Aα in asthmatic airway smooth muscle7
Exercise adaptations in COPD: the pulmonary perspective7
Separating the contributions of SLC26A9 and CFTR to anion secretion in primary human bronchial epithelia7
Aerosolized vitamin E acetate causes oxidative injury in mice and in alveolar macrophages7
Selenium modulates perinatal pulmonary vascular responses to hyperoxia7
Sex-specific differences in plasma levels of FXII, HK, and FXIIa-C1-esterase inhibitor complexes in community-acquired pneumonia7
MiR-223 is increased in lungs of patients with COPD and modulates cigarette smoke-induced pulmonary inflammation7
Changes in respiratory mechanics in response to crystalloid infusions in extremely premature infants7
Toll-like receptors: shapers of the pulmonary microbiome?7
Two-pore potassium channel TREK-1 (K2P2.1) regulates NLRP3 inflammasome activity in macrophages7
Inhibition of glutaminase 1 activity reverses airway hyperresponsiveness and decreases IL-1β+ M1s and IL-17 producing ILC3s in high-fat diet-fed obese mice7
TLR4 is required for macrophage efferocytosis during resolution of ventilator-induced lung injury7
Angiotensin-converting enzyme 2 in peripheral lung club cells modulates the susceptibility to SARS-CoV-2 in chronic obstructive pulmonary disease6
Lumacaftor inhibits channel activity of rescued F508del cystic fibrosis transmembrane conductance regulator6
Endoplasmic reticulum stress-induced senescence in human lung fibroblasts6
Nebulized curcumin protects neonatal lungs from antenatal insult in rats6
Philanthropy pushes sarcoidosis forward6
Preclinical evaluation of the epithelial sodium channel inhibitor AZD5634 and implications on human translation6
The magic of communication: the need to study organ and cell communication in pulmonary arterial hypertension-induced right heart failure6
In silico investigation of the viroporin E as a vaccine target against SARS-CoV-26
Mucopolysaccharidosis (MPS IIIA) mice have increased lung compliance and airway resistance, decreased diaphragm strength, and no change in alveolar structure6
Cytokine signature clusters as a tool to compare changes associated with tobacco product use in upper and lower airway samples6
Novel transfection methods in primary lung cell cultures6
The significance of a lack of rhinorrhea in severe coronavirus 19 lung disease6
Nebulized caffeine alleviates airway hyperresponsiveness in a murine asthma model6
The synthetic aminoglycoside ELX-02 induces readthrough of G550X-CFTR producing superfunctional protein that can be further enhanced by CFTR modulators6
The fix is not yet in: recommendation for fixation of lungs within physiological/pathophysiological volume range in preclinical pulmonary structure-function studies6
A murine model of hereditary pulmonary alveolar proteinosis caused by homozygous Csf2ra gene disruption6
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