American Journal of Physiology-Lung Cellular and Molecular Physiology

Article	Citations
Early-life exposure to cigarette smoke primes lung function and DNA methylation changes at Cyp1a1 upon exposure later in life	98
Pulmonary vascular remodeling in Fra-2 transgenic mice is driven by type 2 inflammation and accompanied by pulmonary vascular hyperresponsiveness	84
Carotid bodies mediate glial cell activation and neuroinflammation in the NTS following long-term intermittent hypoxia: role in cardiorespiratory dysfunction	52
The relationship between elastin cross linking and alveolar wall rupture in human pulmonary emphysema	51
Elevated IL-15 concentrations in the sarcoidosis lung are independent of granuloma burden and disease phenotypes	47
Culture conditions differentially regulate the inflammatory niche and cellular phenotype of tracheobronchial basal stem cells	42
Metformin prevents airway hyperreactivity in rats with dietary obesity	42
Lung-kidney interactions and their role in chronic kidney disease-associated pulmonary diseases	38
Analysis of the alveolar shape in 3-D	37
Peer Review Week, 2021	35
Are circulating endothelial cells the next target for transcriptome-level pathway analysis in ARDS?	33
Sex as a biologic variable: evidence from isolated lung endothelial cells	33
A personal appreciation of Mary Ellen Avery for World Prematurity Day	31
The oxygen dissociation curve of blood in COVID-19	31
Reply to Cinelli et al.	30
Moving on from clinical animal-derived surfactants to peptide-based synthetic pulmonary surfactant	29
PINK1 mediates the protective effects of thyroid hormone T3 in hyperoxia-induced lung injury	28
Every breath you take: exploring macrophages and environmental exposures in the lung—a tribute to Dr. Joseph Brain’s legacy	26
Changes in respiratory mechanics in response to crystalloid infusions in extremely premature infants	26
Reply to Vogel et al.	25
Evidence of sex differences in ozone-induced oxysterol and cytokine levels in differentiated human nasal epithelial cells	25
Effect of smoking cessation on chronic waterpipe smoke inhalation-induced airway hyperresponsiveness, inflammation, and oxidative stress	25
Reply to Gille et al.	25
TRAPping the effects of tobacco smoking: the regulation and function of Acp5 expression in lung macrophages	25
Characteristics, triggers, treatments, and experimental models of neonatal acute respiratory distress syndrome	24

Oxidized phosphatidylcholines induce multiple functional defects in airway epithelial cells	24
The cystathionine-γ-lyase inhibitor DL-propargylglycine augments the ability of L-cysteine ethyl ester to overcome the adverse effects of morphine on breathing	24
Pulmonary capillary blood volume and diffusing membrane capacity during exercise in humans: role of pulmonary artery pressure	23
The developing murine lung is susceptible to acetaminophen toxicity	23
Diet-induced obesity in mice impairs host defense against Klebsiella pneumonia in vivo and glucose transport and bactericidal functions in neutrophils in vitro	23
Impact of tidal volume strategy at birth on initiating lung injury in preterm lambs	22
Leukocyte kinetics and bacterial clearance during Streptococcus pneumoniae pneumonia and contributions of ICAM-1	22
Simple model of pulmonary hypertension secondary to left heart pressure overload induced by partial intravascular occlusion of the ascending aorta	22
Mesenchymal stromal cell extracellular vesicles improve lung development in mechanically ventilated preterm lambs	22
Impact of neonatal noninvasive resuscitation strategies on lung mechanics, tracheal pressure, and tidal volume in preterm lambs	21
Diacylglycerol kinase is a keystone regulator of signaling relevant to the pathophysiology of asthma	21
Mice with lymphatic dysfunction develop pathogenic lung tertiary lymphoid organs that model an autoimmune emphysema phenotype of COPD	20
Mucociliary clearance is impaired in small airways of cystic fibrosis pigs	20
Distinct types of plexiform lesions identified by synchrotron-based phase-contrast micro-CT	20
Targeted stereology: sampling heterogeneously distributed structures and lesions in the lung	20
miR34a: a novel small molecule regulator with a big role in bronchopulmonary dysplasia	20
Endothelial knockdown of the tumor suppressor, WWOX, increases inflammation in ventilator-induced lung injury	20
Immunoglobulin deficiency as an indicator of disease severity in patients with COVID-19	19
PDGFRα-positive cell-derived TIMP-1 modulates adaptive immune responses to influenza A viral infection	19
Effects of spontaneous curvature on interfacial adsorption and collapse of phospholipid monolayers	19
The RNA-binding protein Quaking regulates multiciliated and basal cell abundance in the developing lung	19
Androgen receptor activation alleviates airway hyperresponsiveness, inflammation, and remodeling in a murine model of asthma	19
UCHL1, a deubiquitinating enzyme, regulates lung endothelial cell permeability in vitro and in vivo	18
MiR-223 is increased in lungs of patients with COPD and modulates cigarette smoke-induced pulmonary inflammation	18
Control and challenge of COVID-19: lessons from China’s experience	18
A neutrophil subset defined by intracellular olfactomedin 4 is associated with mortality in sepsis	18
IL-23 amplifies the epithelial-mesenchymal transition of mechanically conditioned alveolar epithelial cells in rheumatoid arthritis-associated interstitial lung disease through mTOR/S6 signaling	18
β-Agonist exposure preferentially impacts lung macrophage cyclic AMP-related gene expression in asthma and asthma COPD overlap syndrome	18
Metabolic signatures of ARDS and ARDS heterogeneity	18
Promoting our early career members at AJP-Lung: the Editorial Board Fellowship Program and the Next Generation Physiologist Highlights section at our Journal	17
PAR-2-activated secretion by airway gland serous cells: role for CFTR and inhibition byPseudomonas aeruginosa	17
The highly packed and dehydrated structure of preformed unexposed human pulmonary surfactant isolated from amniotic fluid	17
Sex differences and altered mitophagy in experimental pulmonary hypertension	17
Looking at the developing lung in single-cell resolution	17
Early extubation to noninvasive respiratory support of former preterm lambs improves long-term respiratory outcomes	17
Genes, other than Muc5b, play a role in bleomycin-induced lung fibrosis	17
Lung proteomic biomarkers associated with chronic obstructive pulmonary disease	16
Cellular mechanism underlying the facilitation of contractile response induced by IL-25 in mouse tracheal smooth muscle	16
Muc5b plays a role in the development of inflammation and fibrosis in hypersensitivity pneumonitis induced bySaccharopolyspora rectivirgula	16
PTPα promotes fibroproliferative responses after acute lung injury	16
Short palate, lung, and nasal epithelial clone 1 (SPLUNC1) level determines steroid-resistant airway inflammation in aging	16
OGR1-dependent regulation of the allergen-induced asthma phenotype	16
ARDS in the time of corona: context and perspective	16
Increased exploration and hyperlocomotion in a cigarette smoke and LPS-induced murine model of COPD: linking pulmonary and systemic inflammation with the brain	16
Spatiotemporal distribution of cellular injury and leukocytes during the progression of ventilator-induced lung injury	16
Cigarette smoke depletes alveolar macrophages and delays clearance of Legionella pneumophila	16
Neonatal hyperoxia induces activated pulmonary cellular states and sex-dependent transcriptomic changes in a model of experimental bronchopulmonary dysplasia	15
Hyperoxia impairs intraflagellar transport and causes dysregulated metabolism with resultant decreased cilia length	15
Wnt5a/β-catenin axis is involved in the downregulation of AT2 lineage by PAI-1	15
Comparison of different methods of initiating lung inflammation and the sex-specific effects on inflammatory parameters	15

A proinflammatory long noncoding RNA Lncenc1 regulates inflammasome activation in macrophage	15
FGF18 promotes human lung branching morphogenesis through regulating mesenchymal progenitor cells	15
Combined repetitive inhalant endotoxin and collagen-induced arthritis drive inflammatory lung disease and arthritis severity in a testosterone-dependent manner	15
Understanding the role of placental pathophysiology in the development of bronchopulmonary dysplasia	15
IL-8 concurrently promotes idiopathic pulmonary fibrosis mesenchymal progenitor cell senescence and PD-L1 expression enabling escape from immune cell surveillance	15
Diet-induced obesity worsens allergen-induced type 2/type 17 inflammation in airways by enhancing DUOX1 activation	15
Rat bronchoalveolar lavage proteome changes following e-cigarette aerosol exposures	15
P2X7 signaling influences the production of pro-resolving and pro-inflammatory lipid mediators in alveolar macrophages derived from individuals with asthma	14
Wnt signaling regulates ion channel expression to promote smooth muscle and cartilage formation in developing mouse trachea	14
The pontine Kölliker-Fuse nucleus is important for reduced postinspiratory airflow elicited by stimulation of the ventral respiratory parafacial region	14
Identification of Siglec-1-negative alveolar macrophages with proinflammatory phenotypes in chronic obstructive pulmonary disease	14
Loss of growth differentiation factor 15 exacerbates lung injury in neonatal mice	14
Two-pore potassium channel TREK-1 (K2P2.1) regulates NLRP3 inflammasome activity in macrophages	14
GAA deficiency disrupts distal airway cells in Pompe disease	14
Biphasic regulation of miR-17∼92 transcription during hypoxia: roles of HIF1 and p53 hyperphosphorylation at ser15	14
Toward in vivo bronchoscopic functional CFTR assessment using a short circuit current measurement probe	14
Feeling good: welcoming the new editorial team for American Journal of Physiology-Lung Cellular and Molecular Physiology	14
T cell and airway smooth muscle interaction: a key driver of asthmatic airway inflammation and remodeling	14
cUMP elicits interendothelial gap formation during Pseudomonas aeruginosa infection	14
Intratracheal administration of mesenchymal stem cell-derived extracellular vesicles reduces lung injuries in a chronic rat model of bronchopulmonary dysplasia	13
A toolbox for studying respiratory viral infections using air-liquid interface cultures of human airway epithelial cells	13
Calponin 1 contributes to myofibroblast differentiation of human pleural mesothelial cells	13
Pulmonary-delivered Anticalin Jagged-1 antagonists reduce experimental airway mucus hyperproduction and obstruction	13
Bulk RNA sequencing of human pediatric lung cell populations reveals unique transcriptomic signature associated with postnatal pulmonary development	13
The misuse of respiratory resistive loading during aerobic exercises: revisiting mechanisms of “standalone” inspiratory muscle training	13
Ginger metabolites and metabolite-inspired synthetic products modulate intracellular calcium and relax airway smooth muscle	13
Lung disease manifestations in Down syndrome	13
Reticulocalbin 3 deficiency in alveolar epithelium attenuated LPS-induced ALI via NF-κB signaling	13
Comprehensive review of lipocalin 2-mediated effects in lung inflammation	13
Endothelial metabolism in pulmonary vascular homeostasis and acute respiratory distress syndrome	13
Evidence for reprogramming of monocytes into reparative alveolar macrophages in vivo by targeting PDE4b	13
The emerging role of extracellular vesicles in bronchopulmonary dysplasia	13
Natural antibodies targeting LPS in pleural effusions of various etiologies	12
A new anesthesia protocol enabling longitudinal lung-function measurements in neonatal rabbits by micro-CT	12
Continuous but not pulsed low-dose fetal betamethasone exposures extend the durability of antenatal steroid therapy	12
A preclinical systematic review and meta-analysis assessing the effect of biological sex in lipopolysaccharide-induced acute lung injury	12
Respiratory benefit in preterm lambs is progressively lost when the concentration of fetal plasma betamethasone is titrated below two nanograms per milliliter	12
Exercise ventilatory response after COVID-19: comparison between ambulatory and hospitalized patients	12
Integral assessment of gas exchange during veno-arterial ECMO: accuracy and precision of a modified Fick principle in a porcine model	12
The lung extracellular matrix protein landscape in severe early-onset and moderate chronic obstructive pulmonary disease	12
Noncanonical JAK1/STAT3 interactions with TGF-β modulate myofibroblast transdifferentiation and fibrosis	12
BATF2 enhances proinflammatory cytokine responses in macrophages and improves early host defense against pulmonary Klebsiella pneumoniae infection	12
Reply to Pantaleón García et al.	12
Decreased LPS-induced lung injury in pigs treated with a lung surfactant protein A-derived nonapeptide that inhibits peroxiredoxin 6 activity and subsequent NOX1,2 activation	12
Mechanosensitive channel Piezo1 is required for pulmonary artery smooth muscle cell proliferation	12
Electronic cigarette exposure disrupts airway epithelial barrier function and exacerbates viral infection	12
Allergic airway inflammation amplifies mast cell responses in isolated guinea pig intralobular bronchi	12
Corrigendum for Audi et al., volume 323, 2022, p. L410–L422	11
Effects of maternal edible THC consumption on offspring lung growth and function in a rhesus macaque model	11
Distinct single-cell transcriptional profile in CD4+ T-lymphocytes among obese children with asthma	11
Call for Papers: “In It for the Long Haul: Understanding the Lasting Impact of COVID-19 on Lung Health and Disease”	11
Biomarkers of alveolar epithelial injury and endothelial dysfunction are associated with scores of pulmonary edema in invasively ventilated patients	11
Lung Endothelial Cell Heterogeneity in Health and Pulmonary Vascular Disease	11
Dynamic driving pressure predicts ventilator-induced lung injury in mice with and without endotoxin-induced acute lung injury	11
Blockade of PD-1 decreases neutrophilic inflammation and lung damage in experimental COPD	11
Exercise adaptations in COPD: the pulmonary perspective	11
Oscillometry of the respiratory system: a translational opportunity not to be missed	11
TLR4 is required for macrophage efferocytosis during resolution of ventilator-induced lung injury	11
Reply to Myslivecek	11
World Prematurity Day: it takes an NIH village to prevent preterm birth and improve treatments for preterm infants	11
CFTR as a therapeutic target for severe lung infection	11
Muscarinic receptors in the nucleus tractus solitarii	11
Early restrictive fluid resuscitation has no clinical advantage in experimental severe pediatric acute respiratory distress syndrome	11
Contribution of fatty acid oxidation to the pathogenesis of pulmonary hypertension	11
Alexander von Humboldt (1769–1859): early high-altitude explorer and renowned plant naturalist	11
Caveolin-1-derived peptide attenuates cigarette smoke-induced airway and alveolar epithelial injury	11
Kidney-lung cross talk during ARDS: mitochondrial DAMPs join the conversation	11
The mysterious case of missing lymphocytes: a cautionary tale of interinstitutional variability in outcomes of lung dissociation protocols	11
Hyaluronan/CD44 axis regulates S100A4-mediated mesenchymal progenitor cell fibrogenicity in idiopathic pulmonary fibrosis	11
Impaired antiviral immunity in frequent exacerbators of chronic obstructive pulmonary disease	11
Activation of platelets and the complement system in mice with Schistosoma-induced pulmonary hypertension	10
Differential temporal development of alveoli and the alveolar capillary network in the postnatal rat lung	10
Lung pericytes as mediators of inflammation	10
Baseline reticular basement membrane morphology is related to subsequent spirometry deterioration in pediatric chronic airway inflammation: a follow-up study	10
Nephronectin is required to maintain right lung lobar separation during embryonic development	10
Moving bronchopulmonary dysplasia research from the bedside to the bench	10
Differential airway remodeling changes were observed in patients with asthma COPD overlap compared to patients with asthma and COPD alone	10
Functional α7 nicotinic receptors in human airway smooth muscle increase intracellular calcium concentration and contractility in asthmatics	10
Cigarette smoke-induced injury induces distinct sex-specific transcriptional signatures in mice tracheal epithelial cells	10
A gel-coated air-liquid-interface culture system with tunable substrate stiffness matching healthy and diseased lung tissues	10

Low-dose vanadium pentoxide perturbed lung metabolism associated with inflammation and fibrosis signaling in male animal and in vitro models	10
Retraction for Li et al., volume 316, 2019, p. L1107–L1117	10
Activation of TREK-1 (K2P2.1) potassium channels protects against influenza A-induced lung injury	10
Mitoquinone mesylate attenuates pathological features of lean and obese allergic asthma in mice	10
Thoracoabdominal asynchrony in a virtual preterm infant: computational modeling and analysis	10
Origins of pathological myofibroblasts in lung fibrosis: insights from lineage tracing mouse models in the single-cell RNA sequencing era	10
Diesel exhaust particles induce polarization state-dependent functional and transcriptional changes in human monocyte-derived macrophages	10
Genetic deficiency of the transcription factor NFAT1 confers protection against fibrogenic responses independent of immune influx	9
Low-volume ventilation of preinjured lungs degrades lung function via stress concentration and progressive alveolar collapse	9
Activation of alveolar epithelial ER stress by β-coronavirus infection disrupts surfactant homeostasis in mice: implications for COVID-19 respiratory failure	9
Preservation of recipient plasma sphingosine-1-phosphate levels reduces transfusion-related acute lung injury	9
BPIFB1 loss alters airway mucus properties and diminishes mucociliary clearance	9
Effect of estrogen receptor α on cardiopulmonary adaptation to chronic developmental hypoxia in a rat model	9
Pseudomonas aeruginosa ExoY infection of pulmonary microvascular endothelial cells releases cyclic nucleotides into the extracellular compartment	9
Alpha-1 antitrypsin inhibits fractalkine-mediated monocyte-lung endothelial cell interactions	9
MAP2K1 dampens cigarette smoke-induced inflammation via suppression of type I interferon pathway activation	9
Citrullination, a novel posttranslational modification of elastin, is involved in COPD pathogenesis	9
Effects of patient pleural effusion fluids on the BBSome components expression of human benign mesothelial cells	9
Chronic alcohol use primes bronchial cells for altered inflammatory response and barrier dysfunction during SARS-CoV-2 infection	9
Brg1/PRMT5 nuclear complex epigenetically regulates FOXO1 in IPF mesenchymal progenitor cells	9
Viral airway injury promotes cell engraftment in an in vitro model of cystic fibrosis cell therapy	9
Gamma secretase activating protein promotes end-organ dysfunction after bacterial pneumonia	9
Maternal high-fat diet changes breathing pattern and causes excessive sympathetic discharge in juvenile offspring rat	9
Cigarette smoking prolongs inflammation associated with influenza infection and delays its clearance in mice	9
Therapeutic characteristics of alveolar-like macrophages in mouse models of hyperoxia and LPS-induced lung inflammation	9
Aryl hydrocarbon receptor activation alters immune cell populations in the lung and bone marrow during coronavirus infection	9