OOIR: Observatory of International Research

Papers

(The median citation count of Critical Reviews in Clinical Laboratory Sciences is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)

Article	Citations
The anion gap as a predictive tool for morbidity and mortality	61
Deep learning algorithms and Raman spectroscopy in the clinical laboratory setting	57
The dual roles of microorganisms in inflammatory diseases: initiators and regulators	49
Machine learning-based error detection in the clinical laboratory: a critical review	47
Data analytics for error detection in clinical laboratories	43
Lipoprotein(a): a genetically determined risk factor for Cardiovascular disease	35
Advances and challenges in the measurement of 1,25-dihydroxyvitamin D: a comprehensive review	34
Human telomere length detected by quantitative fluorescent in situ hybridization: overlooked importance and application	33
Transthyretin mutagenesis: impact on amyloidogenesis and disease	32
Single cell mechanodeformation signatures as early biomarkers for hematological malignancies	31
Copeptin as a surrogate marker for arginine vasopressin: analytical insights, current utility, and emerging applications	27
Clinical utility of human epididymis protein 4	25
The therapeutic relevance of the Kallikrein-Kinin axis in SARS-cov-2-induced vascular pathology	24
Comparison of liquid biopsy-based technologies for cancer screening	24
Cardiovascular disease lipids and lipoproteins biomarker standardization	23
Beyond newborn screening: the role of reverse cascade testing in familial disease detection	23
One health and laboratory medicine: challenges and perspectives for antimicrobial resistance, emerging infections, and food/water security	21
Guidance for securing approvals for new biomarkers: from discovery to clinical implementation	21
KIF2C/MCAK a prognostic biomarker and its oncogenic potential in malignant progression, and prognosis of cancer patients: a systematic review and meta-analysis as biomarker	21
Development of next-generation reference interval models to establish reference intervals based on medical data: current status, algorithms and future consideration	20
Mid-regional pro-atrial natriuretic peptide in managing cardiovascular and cerebrovascular diseases	20
Challenges of insulin-like growth factor-1 testing	19
It’s in the blood: a review of the hematological system in SARS-CoV-2-associated COVID-19	19
Omics-based computational approaches for biomarker identification, prediction, and treatment of Long COVID	18
Blood biomarkers for the diagnosis of chorioamnionitis following preterm premature rupture of membranes: a systematic review and meta-analysis of studies since 2020	18

Association of inflammatory biomarkers with morbidity and mortality risk in patients with peripheral artery disease: a systematic review and meta-analysis	18
Analytical and clinical considerations of synovial fluid calprotectin in diagnosing periprosthetic joint infections	17
The intersection of the laboratory and transgender care	16
Emerging applications of machine learning in genomic medicine and healthcare	16
Therapeutic biomarkers in metastatic castration-resistant prostate cancer: does the state matter?	15
Pleural fluid biomarkers for the diagnosis and management of malignant pleural effusions: a clinical review	14
Methodological and conceptual challenges to the flow cytometric classification of leukemic lymphoproliferative disorders	12
Diagnostic stewardship monitoring systems: institutional and system-level approaches	12
The urocortin peptides: biological relevance and laboratory aspects of UCN3 and its receptor	12
General features, pathogenesis, and laboratory diagnostics of autoimmune encephalitis	12
Guidelines for diagnosing and differentiating infection with antifungal-resistant Trichophyton indotineae from other dermatophytoses	11
Pathogenicity and virulence of human T lymphotropic virus type-1 (HTLV-1) in oncogenesis: adult T-cell leukemia/lymphoma (ATLL)	11
Insight into metabolic dysregulation of polycystic ovary syndrome utilizing metabolomic signatures: a narrative review	11
Circulating tumor DNA (ctDNA): can it be used as a pan-cancer early detection test?	11
Advances in internal quality control	10
Diagnostic performance and heterogeneity of validated flow cytometry scores: a systematic review	10
DNA/RNA-based electrochemical nanobiosensors for early detection of cancers	10
Glycation and disease: a systematic review of the analytical methods and applications of advanced glycation end products (AGEs) as biomarkers of disease	10
From fructose to the future: liver disease biomarkers and their prognostic value in acute liver failure	9
Erroneous potassium results: preanalytical causes, detection, and corrective actions	9
The multidimensional value of natriuretic peptides in heart failure, integrating laboratory and clinical aspects	9
Free thyroxine measurement in clinical practice: how to optimize indications, analytical procedures, and interpretation criteria while waiting for global standardization	9
Point of care blood glucose devices in the hospital setting	8
Omics-based novel strategies in the diagnosis of endometriosis	8
Establishing, evaluating and monitoring analytical quality in the traceability era	8
Genotype-phenotype correlation in the spectrum of frontotemporal dementia-parkinsonian syndromes and advanced diagnostic approaches	8
Genetic variants of accessory proteins and G proteins in human genetic disease	8
Research progress of KL-6 in respiratory system diseases	8
Correction	8
Pre-analytical conditions and implementation of quality control steps in liquid biopsy analysis	7
Estimating glomerular filtration rate with new equations: can one size ever fit all?	7
Analytical performance specifications and quality assurance of point-of-care testing in primary healthcare	7
Current practices in the diagnosis of Lyme disease	7
Loop-mediated isothermal amplification (LAMP)-based microbial detection: a review of FDA-authorized tests and future perspectives	6
Beyond the amyloid hypothesis: how current research implicates autoimmunity in Alzheimer’s disease pathogenesis	6
Unveiling Parkinson’s disease through biomarker research: current insights and future prospects	6
Large scale implementation of DP for clinical diagnoses: experience, challenges, and lessons learned	6
From population-based to personalized laboratory medicine: continuous monitoring of individual laboratory data with wearable biosensors	6
Pathologist workload, burnout, and wellness: connecting the dots	6
Parallelism in neurodegenerative biomarker tests: hidden errors and the risk of misconduct	6
Technical quality assurance and quality control for medical laboratories: a review and proposal of a new concept to obtain integrated and validated QA/QC plans	5
Implication of calcium supplementations in health and diseases with special focus on colorectal cancer	5
Advances in minimal residual disease monitoring in multiple myeloma	5
The European Organisation of External Quality Assurance Providers in Laboratory Medicine (EQALM) Statement: guidelines for publishing about interlaboratory comparison studies (PubILC)	5
Machine learning models for acute kidney injury prediction and management: a scoping review of externally validated studies	5
The current state in liquid chromatography-mass spectrometry methods for quantifying kynurenine pathway metabolites in biological samples: a systematic review	5
Mapping the evidence: a scoping review of the impact of COVID-19 on non-communicable disease care in Sub-Saharan Africa	5
The significance of antigen-antibody-binding avidity in clinical diagnosis	5
Implementation of pharmacogenomics testing for precision medicine	5
The role of immunophenotyping in common variable immunodeficiency: a narrative review	5