OOIR: Observatory of International Research

Papers

(The median citation count of Critical Reviews in Clinical Laboratory Sciences is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Genetic variants of accessory proteins and G proteins in human genetic disease	108
The role of immunophenotyping in common variable immunodeficiency: a narrative review	92
Within-subject biological variation estimated using real-world data strategies (RWD): a systematic review	81
It’s in the blood: a review of the hematological system in SARS-CoV-2-associated COVID-19	64
Unlocking the link between haptoglobin polymorphism and noninfectious human diseases: insights and implications	43
Advances and challenges in the measurement of 1,25-dihydroxyvitamin D: a comprehensive review	33
Physiological and metabolic adaptations in pregnancy: importance of trimester-specific reference intervals to investigate maternal health and complications	33
Molecular effects of ozone on amino acids and proteins, especially human hemoglobin and albumin, and the need to personalize ozone concentration in major ozone autohemotherapy	29
Lipoprotein(a): a genetically determined risk factor for Cardiovascular disease	28
Preterm labor tests: current status and future directions	27
A review of clinical guidelines, laboratory recommendations and external quality assurance programs for monoclonal gammopathy testing	26
G protein-coupled receptor (GPCR) pharmacogenomics	22
Research progress of KL-6 in respiratory system diseases	22
Genotype-phenotype correlation in the spectrum of frontotemporal dementia-parkinsonian syndromes and advanced diagnostic approaches	22
Liquid biopsy for the management of NSCLC patients under osimertinib treatment	21
Vitamin B₁₂status in health and disease: a critical review. Diagnosis of deficiency and insufficiency – clinical and laboratory pitfalls	21
Omics-based novel strategies in the diagnosis of endometriosis	21
The molecular structure and biological functions of RNA methylation, with special emphasis on the roles of RNA methylation in autoimmune diseases	19
The European Organisation of External Quality Assurance Providers in Laboratory Medicine (EQALM) Statement: guidelines for publishing about interlaboratory comparison studies (PubILC)	19
Breathing new life into clinical testing and diagnostics: perspectives on volatile biomarkers from breath	16
Challenges of insulin-like growth factor-1 testing	16
The elusive male microbiome: revealing the link between the genital microbiota and fertility. Critical review and future perspectives	14
Current status in cellular-based therapies for prevention and treatment of COVID-19	13
The significance of antigen-antibody-binding avidity in clinical diagnosis	12
Copeptin as a surrogate marker for arginine vasopressin: analytical insights, current utility, and emerging applications	12

Impact of body mass index on growth hormone stimulation tests in children and adolescents: a systematic review and meta-analysis	12
Technical quality assurance and quality control for medical laboratories: a review and proposal of a new concept to obtain integrated and validated QA/QC plans	11
Lipid-binding antiphospholipid antibodies: significance for pathophysiology and diagnosis of the antiphospholipid syndrome	11
Choice of SARS-CoV-2 diagnostic test: challenges and key considerations for the future	11
Design, optimization, and application of multiplex rRT-PCR in the detection of respiratory viruses	11
Reference intervals: past, present, and future	11
Clinical utility of procalcitonin and its association with pathogenic microorganisms	10
Lean and Six Sigma as continuous quality improvement frameworks in the clinical diagnostic laboratory	10
Procalcitonin for individualizing antibiotic treatment: an update with a focus on COVID-19	10
Emerging applications of machine learning in genomic medicine and healthcare	10
Correction	10
Human telomere length detected by quantitative fluorescent in situ hybridization: overlooked importance and application	9
Analytical and clinical considerations of synovial fluid calprotectin in diagnosing periprosthetic joint infections	9
Transthyretin mutagenesis: impact on amyloidogenesis and disease	9
Inherited causes of exocrine pancreatic insufficiency in pediatric patients: clinical presentation and laboratory testing	8
DropWise: current role and future perspectives of dried blood spots (DBS), blood microsampling, and their analysis in sports drug testing	8
G protein-coupled receptor (GPCR) gene variants and human genetic disease	8
Current and emerging technologies for the timely screening and diagnosis of neonatal jaundice	8
Using a systematic approach to strategic innovation in laboratory medicine to bring about change	8
Therapeutic biomarkers in metastatic castration-resistant prostate cancer: does the state matter?	7
Newborn screening of mucopolysaccharidosis type I	7
Complement testing in the clinical laboratory	7
Artificial intelligence in serum protein electrophoresis: history, state of the art, and perspective	7
Laboratory biomarkers in the diagnosis and follow-up of treatment of allergic bronchopulmonary aspergillosis in cystic fibrosis	7
Managing biological variation data: modern approaches for study design and clinical application	7
The therapeutic relevance of the Kallikrein-Kinin axis in SARS-cov-2-induced vascular pathology	7
The role of bile acid metabolism in bone and muscle: from analytics to mechanisms	7
Von Willebrand factor and disease: a review for laboratory professionals	6
The role of the clinical laboratory in diagnosing hyponatremia disorders	6
Revisiting approaches to and considerations for urinalysis and urine culture reflexive testing	5
Biomarkers of disease in human nails: a comprehensive review	5
Mapping of audiometric analysis with microbiological findings in patients with chronic suppurative otitis media (CSOM): a neglected clinical manifestation	5
Evaluating thyroid function in pregnant women	5
New biomarkers in acute kidney injury	4
Oligoclonal bands: clinical utility and interpretation cues	4
General features, pathogenesis, and laboratory diagnostics of autoimmune encephalitis	4
Estimating glomerular filtration rate with new equations: can one size ever fit all?	4
Nucleic acid-based electrochemical biosensors for rapid clinical diagnosis: advances, challenges, and opportunities	4
Methodological and conceptual challenges to the flow cytometric classification of leukemic lymphoproliferative disorders	4
Personalized reference intervals: from theory to practice	4
Vitamin D: sources, physiological role, biokinetics, deficiency, therapeutic use, toxicity, and overview of analytical methods for detection of vitamin D and its metabolites	4
The urocortin peptides: biological relevance and laboratory aspects of UCN3 and its receptor	4
Extracellular vesicles in cancer: challenges and opportunities for clinical laboratories	4