OOIR: Observatory of International Research

Papers

(The median citation count of Critical Reviews in Toxicology is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)

Article	Citations
Mechanisms of developmental neurotoxicity mediated by perturbed thyroid hormone homeostasis in the brain: an adverse outcome pathway network	73
Per- and polyfluoroalkyl substances (PFAS): immunotoxicity at the primary sites of exposure	48
Thank you to Reviewers for Critical Reviews in Toxicology	44
Human chlorine gas exposition and its management – an umbrella review on human data	39
Recent advances in electrochemical and optical sensing of the organophosphate chlorpyrifos: a review	36
Potential application of probiotics in mycotoxicosis reduction in mammals and poultry	29
Response to the letter to the editor regarding the article “Weight of evidence evaluation for chemical-induced immunotoxicity for PFOA and PFOS: findings from an independent panel of experts” by Garve	28
Nephrotoxicity induced by natural compounds from herbal medicines – a challenge for clinical application	27
Effects of statins on male reproductive health: a systematic review of rodent studies and their potential implications to human male reproduction	27
Examining the relationship between per-and polyfluoroalkyl substances and breast, colorectal, prostate, and ovarian cancers: a meta-analysis	26
In vitro human brain barrier models for studying thyroid hormone transport	25
Evidence and hypotheses on adverse effects of the food additives carrageenan (E 407)/processed Eucheuma seaweed (E 407a) and carboxymethylcellulose (E 466) on the intestines: a scoping review	24
United States Environmental Protection Agency's Perfluorooctanoic Acid, Perfluorooctane Sulfonic Acid, and Related Per- and Polyfluoroalkyl Substances 2024 Drinking Water Maximum Contaminant Level: Pa	23
Thank you to authors and reviewers of papers in Critical Reviews in Toxicology (CRT) volume 54, 2024	22
Data derived extrapolation factors (DDEFs) for rat to human interspecies extrapolation for the HPPD inhibitor mesotrione	21
A systematic review on fluoride-induced epigenetic toxicity in mammals	21
The IARC re-classification of talc carcinogenicity: a move in the wrong direction?	21
Meta-analysis of the safety and efficacy of fresh frozen plasma exchange in the treatment of organophosphate pesticide poisoning	20
Construction of a risk prediction model of diquat poisoning based on clinical indicators	18
Zebrafish and nematodes as whole organism models to measure developmental neurotoxicity	18
Biomarkers of environmental manganese exposure	18
Evaluating health impacts of exposure to PFAS mixtures: a systematic review of epidemiological studies using mixture methods	17
Evaluation of the human hazard of the liver and lung tumors in mice treated with permethrin based on mode of action	16
Response to letter to the editor on: “the use of canonical dose–response models for benchmark dose analysis of continuous toxicological data”	16
A review of pulmonary neutrophilia and insights into the key role of neutrophils in particle-induced pathogenesis in the lung from animal studies of lunar dusts and other poorly soluble dust particles	15

An updated evaluation of reported no-observed adverse effect levels for chrysotile, amosite, and crocidolite asbestos for lung cancer and mesothelioma	15
In search of certainty beyond the cholinergic system: a systematic review of developmental chlorpyrifos exposure and neurotransmitter systems disruption in preclinical models	15
Complex roles for sulfation in the toxicities of polychlorinated biphenyls	15
Prevention and Detoxification of Mycotoxins in Human Food and Animal Feed using Bio-resources from South Mediterranean Countries: a Critical Review	14
Fiber biodurability and biopersistence: historical toxicological perspective of synthetic vitreous fibers (SVFs), the long fiber paradigm, and implications for advanced materials	14
Assessment of genotoxicity of glass ionomer cements: a systematic review	14
Synthetic vitreous fibers (SVFs): adverse outcome pathways (AOPs) and considerations for next generation new approach methods (NAMs)	13
Human biomonitoring and risks of hazardous occupational exposure to polycyclic aromatic hydrocarbons in wildland fires: a critical review	13
Review of epidemiological and toxicological studies on health effects from ingestion of asbestos in drinking water	13
Towards a science-based testing strategy to identify maternal thyroid hormone imbalance and neurodevelopmental effects in the progeny—part III: how is substance-mediated thyroid hormone imbalance in p	11
Systematic review of studies on exposure to arsenic in drinking water and cognitive and neurobehavioral effects	11
The modes of action for rodent liver tumor formation by activators of the constitutive androstane receptor (CAR) and the peroxisome proliferator-activated receptor alpha (PPARα) are not relevant to hu	11
A systematic review of herbicide safener toxicity	11
Magnetic resonance imaging T1 indices of the brain as biomarkers of inhaled manganese exposure	10
A prioritization strategy for functional alternatives to bisphenol A in food contact materials	10
Female reproductive toxicity after exposure to malathion or diazinon: a systematic review of rodent and human studies	10
Perspectives on aerosol inhalability: concepts and applications	10
A narrative review of converging evidence addressing developmental toxicity of pyrethroid insecticides	10
Gastrointestinal decontamination using oil-based solutions in patients with acute aluminum phosphide poisoning: a systematic review and meta-analysis	10
Implementation of a dermal sensitization threshold (DST) concept for risk assessment: structure-based DST and in vitro data-based DST	10
Dietary psychoactive xenobiotics: an updated review on food contamination with ergot, tropane and opium alkaloids and their toxicological effects	9
From cultivation to cancer: formation of N -nitrosamines and other carcinogens in smokeless tobacco and their mutagenic implications	9
A quantitative weight-of-evidence review of preclinical studies examining the potential developmental and reproductive toxicity of acetaminophen	9
What can we learn from epidemiological studies on chronic boron exposure?	9
Occupational exposure assessment with solid substances: choosing a vehicle for in vitro percutaneous absorption experiments	9
Mechanisms of neurodevelopmental toxicity of topiramate	9
Exploring research gaps and trends in the management of acute phosphide poisoning: a systematic review	9
Evaluating the conduct and reporting of the T-cell dependent antibody response in the Extended One-Generation Reproductive Toxicity study provided under the EU REACH regulation	8
Investigations on learning and memory function in extended one-generation reproductive toxicity studies – when considered needed and based on what?	8
Mode of action approach supports a lack of carcinogenic potential of six organic UV filters	8
Malathion or diazinon exposure and male reproductive toxicity: a systematic review of studies performed with rodents	7
Letter to the editor regarding the review article by Yamada et al. (2021) titled “Critical evaluation of the human relevance of the mode of action for rodent liver tumor formation by activators of the	7
The methodological rigour of systematic reviews in environmental health	7
Adverse outcome pathway (AOP): α2u-globulin nephropathy and kidney tumors in male rats	7
A weight of evidence review on the mode of action, adversity, and the human relevance of xylene’s observed thyroid effects in rats	7
Human biomonitoring of low-level benzene exposures	7
The use of canonical dose–response models for benchmark dose analysis of continuous toxicological data	7
Framework for sensitization assessment of extractables and leachables in pharmaceuticals	7
Correction	6
A critical review to identify data gaps and improve risk assessment of bisphenol A alternatives for human health	6
Animal models of developmental toxicity induced by early life electronic-cigarettes exposure	6
Fungicides as a risk factor for the development of neurological diseases and disorders in humans: a systematic review	6
Correction	6
Low level exposure to hydrogen sulfide: a review of emissions, community exposure, health effects, and exposure guidelines	6
Diagnosis, toxicological mechanism, and detoxification for hepatotoxicity induced by pyrrolizidine alkaloids from herbal medicines or other plants	5
Overview of analytical methods for determining novel psychoactive substances, drugs and their metabolites in biological samples	5
Mechanistic insights regarding neuropsychiatric and neuropathologic impacts of air pollution	5
Molecular similarity in chemical informatics and predictive toxicity modeling: from quantitative read-across (q-RA) to quantitative read-across structure–activity relationship (q-RASAR) with the appli	5
Temephos, an organophosphate larvicide for residential use: a review of its toxicity	5
European Food Safety Authority database for in vivo developmental neurotoxicity studies of pesticides	5

25X-NBOMe compounds – chemistry, pharmacology and toxicology. A comprehensive review	5
Modeling the human placenta: in vitro applications in developmental and reproductive toxicology	4
Regulatory roles of extracellular vesicles in adverse pregnancy outcomes exposed with environmental toxicants	4
Response to Letter to the Editor from Drs. van Kesteren, Pronk, Heusinkveld, Luijten and Hakkert concerning Yamada et al. (2021): Critical evaluation of the human relevance of the mode of action for r	4
A framework for integrating evidence to assess hazards and risk	4
The tradeoff between the efficacy of calcineurin inhibitors: prevention of allograft rejection vs. post-transplant renal and cardiovascular complications	4
Where should I start? A scoping review about the publications on clove cigarettes	4
Projection of future numbers of mesothelioma cases in the US and the increasing prevalence of background cases: an update based on SEER data for 1975 through 2018	4
Towards a science-based testing strategy to identify maternal thyroid hormone imbalance and neurodevelopmental effects in the progeny – Part IV: the ECETOC and CLE Proposal for a Thyroid Function-Rela	4
Mycotoxins occurrence in milk and cereals in North African countries – a review	4
Non-acute exposure of neonicotinoids, health risk assessment, and evidence integration: a systematic review	4
Immunotoxicity of engineered nanomaterials and their role in asthma	4
Molecular insights into the role of electronic cigarettes in oral carcinogenesis	4
Toxicity of chemical-based hand sanitizers on children and the development of natural alternatives: a computational approach	4