OOIR: Observatory of International Research

Papers

(The median citation count of Critical Reviews in Toxicology is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)

Article	Citations
Per- and polyfluoroalkyl substances (PFAS): immunotoxicity at the primary sites of exposure	72
Mechanisms of developmental neurotoxicity mediated by perturbed thyroid hormone homeostasis in the brain: an adverse outcome pathway network	66
Thank you to Reviewers for Critical Reviews in Toxicology	44
Recent advances in electrochemical and optical sensing of the organophosphate chlorpyrifos: a review	37
Potential application of probiotics in mycotoxicosis reduction in mammals and poultry	32
Human chlorine gas exposition and its management – an umbrella review on human data	31
Response to the letter to the editor regarding the article “Weight of evidence evaluation for chemical-induced immunotoxicity for PFOA and PFOS: findings from an independent panel of experts” by Garve	30
Effects of statins on male reproductive health: a systematic review of rodent studies and their potential implications to human male reproduction	25
Examining the relationship between per-and polyfluoroalkyl substances and breast, colorectal, prostate, and ovarian cancers: a meta-analysis	25
EDC-induced mechanisms of immunotoxicity: a systematic review	24
Nephrotoxicity induced by natural compounds from herbal medicines – a challenge for clinical application	24
Thank you to authors and reviewers of papers in Critical Reviews in Toxicology (CRT) volume 54, 2024	22
Evidence and hypotheses on adverse effects of the food additives carrageenan (E 407)/processed Eucheuma seaweed (E 407a) and carboxymethylcellulose (E 466) on the intestines: a scoping review	22
United States Environmental Protection Agency's Perfluorooctanoic Acid, Perfluorooctane Sulfonic Acid, and Related Per- and Polyfluoroalkyl Substances 2024 Drinking Water Maximum Contaminant Level: Pa	22
A systematic review on fluoride-induced epigenetic toxicity in mammals	21
A mechanistic evaluation of the potential for octamethylcyclotetrasiloxane to produce effects via endocrine modes of action	19
Data derived extrapolation factors (DDEFs) for rat to human interspecies extrapolation for the HPPD inhibitor mesotrione	19
Evaluation of the human hazard of the liver and lung tumors in mice treated with permethrin based on mode of action	17
Construction of a risk prediction model of diquat poisoning based on clinical indicators	17
Zebrafish and nematodes as whole organism models to measure developmental neurotoxicity	17
Biomarkers of environmental manganese exposure	17
A review of pulmonary neutrophilia and insights into the key role of neutrophils in particle-induced pathogenesis in the lung from animal studies of lunar dusts and other poorly soluble dust particles	16
An examination of historical control histopathology metadata from 51 Amphibian Metamorphosis Assays	15
An updated evaluation of reported no-observed adverse effect levels for chrysotile, amosite, and crocidolite asbestos for lung cancer and mesothelioma	13
Assessment of genotoxicity of glass ionomer cements: a systematic review	13

Fiber biodurability and biopersistence: historical toxicological perspective of synthetic vitreous fibers (SVFs), the long fiber paradigm, and implications for advanced materials	13
Complex roles for sulfation in the toxicities of polychlorinated biphenyls	13
Review of epidemiological and toxicological studies on health effects from ingestion of asbestos in drinking water	12
Synthetic vitreous fibers (SVFs): adverse outcome pathways (AOPs) and considerations for next generation new approach methods (NAMs)	11
Human biomonitoring and risks of hazardous occupational exposure to polycyclic aromatic hydrocarbons in wildland fires: a critical review	11
Prevention and Detoxification of Mycotoxins in Human Food and Animal Feed using Bio-resources from South Mediterranean Countries: a Critical Review	11
Thank you to reviewers for Critical Reviews In Toxicology	11
A systematic review of herbicide safener toxicity	11
Letter to the editor, regarding the publication by Carrillo and colleagues, “Relevance of animal studies in the toxicological assessment of oil and wax hydrocarbons. Solving the puzzle for a new outlo	11
Systematic review of studies on exposure to arsenic in drinking water and cognitive and neurobehavioral effects	11
The modes of action for rodent liver tumor formation by activators of the constitutive androstane receptor (CAR) and the peroxisome proliferator-activated receptor alpha (PPARα) are not relevant to hu	10
Implementation of a dermal sensitization threshold (DST) concept for risk assessment: structure-based DST and in vitro data-based DST	10
Using the Matrix to bridge the epidemiology/risk assessment gap: a case study of 2,4-D	10
A critical review of the kinetic direct peptide reactivity assay (kDPRA) for skin sensitizer potency assessment – taking it forward	9
Towards a science-based testing strategy to identify maternal thyroid hormone imbalance and neurodevelopmental effects in the progeny—part III: how is substance-mediated thyroid hormone imbalance in p	9
Exploring research gaps and trends in the management of acute phosphide poisoning: a systematic review	9
A prioritization strategy for functional alternatives to bisphenol A in food contact materials	9
Magnetic resonance imaging T1 indices of the brain as biomarkers of inhaled manganese exposure	9
A narrative review of converging evidence addressing developmental toxicity of pyrethroid insecticides	9
Gastrointestinal decontamination using oil-based solutions in patients with acute aluminum phosphide poisoning: a systematic review and meta-analysis	9
What can we learn from epidemiological studies on chronic boron exposure?	9
Perspectives on aerosol inhalability: concepts and applications	9
From cultivation to cancer: formation of N -nitrosamines and other carcinogens in smokeless tobacco and their mutagenic implications	8
Dietary psychoactive xenobiotics: an updated review on food contamination with ergot, tropane and opium alkaloids and their toxicological effects	8
Evaluating the conduct and reporting of the T-cell dependent antibody response in the Extended One-Generation Reproductive Toxicity study provided under the EU REACH regulation	8
A quantitative weight-of-evidence review of preclinical studies examining the potential developmental and reproductive toxicity of acetaminophen	8
Mechanisms of neurodevelopmental toxicity of topiramate	8
Occupational exposure assessment with solid substances: choosing a vehicle for in vitro percutaneous absorption experiments	8
Investigations on learning and memory function in extended one-generation reproductive toxicity studies – when considered needed and based on what?	7
The use of canonical dose–response models for benchmark dose analysis of continuous toxicological data	7
Mode of action approach supports a lack of carcinogenic potential of six organic UV filters	7
The methodological rigour of systematic reviews in environmental health	7
Adverse outcome pathway (AOP): α2u-globulin nephropathy and kidney tumors in male rats	7
Malathion or diazinon exposure and male reproductive toxicity: a systematic review of studies performed with rodents	7
Framework for sensitization assessment of extractables and leachables in pharmaceuticals	7
Low level exposure to hydrogen sulfide: a review of emissions, community exposure, health effects, and exposure guidelines	6
Assessing chemical carcinogenicity: hazard identification, classification, and risk assessment. Insight from a Toxicology Forum state-of-the-science workshop	6
Human biomonitoring of low-level benzene exposures	6
Fungicides as a risk factor for the development of neurological diseases and disorders in humans: a systematic review	6
Correction	6
Animal models of developmental toxicity induced by early life electronic-cigarettes exposure	6
A weight of evidence review on the mode of action, adversity, and the human relevance of xylene’s observed thyroid effects in rats	6
A critical review to identify data gaps and improve risk assessment of bisphenol A alternatives for human health	6
Correction	6
Letter to the editor regarding the review article by Yamada et al. (2021) titled “Critical evaluation of the human relevance of the mode of action for rodent liver tumor formation by activators of the	6
Overview of analytical methods for determining novel psychoactive substances, drugs and their metabolites in biological samples	5
25X-NBOMe compounds – chemistry, pharmacology and toxicology. A comprehensive review	5
Mechanistic insights regarding neuropsychiatric and neuropathologic impacts of air pollution	5
European Food Safety Authority database for in vivo developmental neurotoxicity studies of pesticides	4
Molecular similarity in chemical informatics and predictive toxicity modeling: from quantitative read-across (q-RA) to quantitative read-across structure–activity relationship (q-RASAR) with the appli	4

Toxicity of chemical-based hand sanitizers on children and the development of natural alternatives: a computational approach	4
Identifying a reference list of respiratory sensitizers for the evaluation of novel approaches to study respiratory sensitization	4
Diagnosis, toxicological mechanism, and detoxification for hepatotoxicity induced by pyrrolizidine alkaloids from herbal medicines or other plants	4
A review of mammalianin vivogenotoxicity of hexavalent chromium: implications for oral carcinogenicity risk assessment	4
Temephos, an organophosphate larvicide for residential use: a review of its toxicity	4
Non-acute exposure of neonicotinoids, health risk assessment, and evidence integration: a systematic review	4
Assessment of metal ion accumulation in oral mucosa cells of patients with fixed orthodontic treatment and cellular DNA damage: a systematic review	4