OOIR: Observatory of International Research

Papers

(The median citation count of Critical Reviews in Toxicology is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
Per- and polyfluoroalkyl substances (PFAS): immunotoxicity at the primary sites of exposure	120
Mechanisms of developmental neurotoxicity mediated by perturbed thyroid hormone homeostasis in the brain: an adverse outcome pathway network	68
Thank you to Reviewers for Critical Reviews in Toxicology	65
Potential application of probiotics in mycotoxicosis reduction in mammals and poultry	48
Response to the letter to the editor regarding the article “Weight of evidence evaluation for chemical-induced immunotoxicity for PFOA and PFOS: findings from an independent panel of experts” by Garve	35
Nephrotoxicity induced by natural compounds from herbal medicines – a challenge for clinical application	33
Examining the relationship between per-and polyfluoroalkyl substances and breast, colorectal, prostate, and ovarian cancers: a meta-analysis	32
Effects of statins on male reproductive health: a systematic review of rodent studies and their potential implications to human male reproduction	31
Letter to the Editor: Comprehensive review of octocrylene toxicology data and human exposure assessment for personal care products	29
In vitro human brain barrier models for studying thyroid hormone transport	28
Evidence and hypotheses on adverse effects of the food additives carrageenan (E 407)/processed Eucheuma seaweed (E 407a) and carboxymethylcellulose (E 466) on the intestines: a scoping review	28
United States Environmental Protection Agency's Perfluorooctanoic Acid, Perfluorooctane Sulfonic Acid, and Related Per- and Polyfluoroalkyl Substances 2024 Drinking Water Maximum Contaminant Level: Pa	27
Thank you to authors and reviewers of papers in Critical Reviews in Toxicology (CRT) volume 54, 2024	26
The IARC re-classification of talc carcinogenicity: a move in the wrong direction?	25
Construction of a risk prediction model of diquat poisoning based on clinical indicators	22
Data derived extrapolation factors (DDEFs) for rat to human interspecies extrapolation for the HPPD inhibitor mesotrione	22
Microplastic trafficking in maternal-fetal system: a systematic review and quantitative profiling linking particle characteristics to developmental biology	21
A review of pulmonary neutrophilia and insights into the key role of neutrophils in particle-induced pathogenesis in the lung from animal studies of lunar dusts and other poorly soluble dust particles	20
Meta-analysis of the safety and efficacy of fresh frozen plasma exchange in the treatment of organophosphate pesticide poisoning	20
Response to letter to the editor on: “the use of canonical dose–response models for benchmark dose analysis of continuous toxicological data”	20
Zebrafish and nematodes as whole organism models to measure developmental neurotoxicity	20
Evaluating health impacts of exposure to PFAS mixtures: a systematic review of epidemiological studies using mixture methods	18
In search of certainty beyond the cholinergic system: a systematic review of developmental chlorpyrifos exposure and neurotransmitter systems disruption in preclinical models	18
Letter to the editor regarding the review article: Yamada T, Cohen SM, Lake BG. The modes of action for rodent liver tumor formation by activators of the constitutive androstane receptor (CAR) and the	17
Complex roles for sulfation in the toxicities of polychlorinated biphenyls	16

Prevention and Detoxification of Mycotoxins in Human Food and Animal Feed using Bio-resources from South Mediterranean Countries: a Critical Review	14
Synthetic vitreous fibers (SVFs): adverse outcome pathways (AOPs) and considerations for next generation new approach methods (NAMs)	14
An updated evaluation of reported no-observed adverse effect levels for chrysotile, amosite, and crocidolite asbestos for lung cancer and mesothelioma	14
Review of epidemiological and toxicological studies on health effects from ingestion of asbestos in drinking water	14
Fiber biodurability and biopersistence: historical toxicological perspective of synthetic vitreous fibers (SVFs), the long fiber paradigm, and implications for advanced materials	14
Human biomonitoring and risks of hazardous occupational exposure to polycyclic aromatic hydrocarbons in wildland fires: a critical review	13
Wildfires in the Pan-Amazon: what is known about health impacts on affected populations?	13
Systematic review of studies on exposure to arsenic in drinking water and cognitive and neurobehavioral effects	13
The modes of action for rodent liver tumor formation by activators of the constitutive androstane receptor (CAR) and the peroxisome proliferator-activated receptor alpha (PPARα) are not relevant to hu	12
A systematic review of herbicide safener toxicity	12
The formaldehyde dispute – Part B: scientific critique of EPA’s formaldehyde occupational exposure values (OEVs) and proposed alternative occupational exposure limits (OELs)	12
Towards a science-based testing strategy to identify maternal thyroid hormone imbalance and neurodevelopmental effects in the progeny—part III: how is substance-mediated thyroid hormone imbalance in p	11
Role of constitutive androstane receptor in developmental toxicology: linking chemical exposure, nutrition, and disease susceptibility	11
Gastrointestinal decontamination using oil-based solutions in patients with acute aluminum phosphide poisoning: a systematic review and meta-analysis	11
A prioritization strategy for functional alternatives to bisphenol A in food contact materials	11
Perspectives on aerosol inhalability: concepts and applications	10
Female reproductive toxicity after exposure to malathion or diazinon: a systematic review of rodent and human studies	10
From cultivation to cancer: formation of N -nitrosamines and other carcinogens in smokeless tobacco and their mutagenic implications	9
A quantitative weight-of-evidence review of preclinical studies examining the potential developmental and reproductive toxicity of acetaminophen	9
Dietary psychoactive xenobiotics: an updated review on food contamination with ergot, tropane and opium alkaloids and their toxicological effects	9
Comprehensive review of octocrylene toxicology data and human exposure assessment for personal care products	9
Mechanisms of neurodevelopmental toxicity of topiramate	9
Investigations on learning and memory function in extended one-generation reproductive toxicity studies – when considered needed and based on what?	9
Exploring research gaps and trends in the management of acute phosphide poisoning: a systematic review	9
What can we learn from epidemiological studies on chronic boron exposure?	9
Response to the Letter from Professor C. R. Wolf and colleagues concerning CRT, 55: 549–586, 2025: The modes of action for rodent liver tumor formation by activators of the constitutive androstane rec	9
Setting occupational exposure limits (OELs) for carcinogens: a focus on benzene	8
Human biomonitoring of low-level benzene exposures	8
Mode of action approach supports a lack of carcinogenic potential of six organic UV filters	8
Inhalation exposure and health effects of copper particles in the context of occupational exposure limit derivation	8
Evaluating the conduct and reporting of the T-cell dependent antibody response in the Extended One-Generation Reproductive Toxicity study provided under the EU REACH regulation	8
The use of canonical dose–response models for benchmark dose analysis of continuous toxicological data	8
Malathion or diazinon exposure and male reproductive toxicity: a systematic review of studies performed with rodents	8
A weight of evidence review on the mode of action, adversity, and the human relevance of xylene’s observed thyroid effects in rats	7
Low level exposure to hydrogen sulfide: a review of emissions, community exposure, health effects, and exposure guidelines	7
A framework for assessing the safety of degraded pharmaceuticals for long-duration space missions - Part 2: framework application in four case studies	7
A critical review to identify data gaps and improve risk assessment of bisphenol A alternatives for human health	7
Fungicides as a risk factor for the development of neurological diseases and disorders in humans: a systematic review	6
Mechanistic insights regarding neuropsychiatric and neuropathologic impacts of air pollution	6
Molecular similarity in chemical informatics and predictive toxicity modeling: from quantitative read-across (q-RA) to quantitative read-across structure–activity relationship (q-RASAR) with the appli	6
Animal models of developmental toxicity induced by early life electronic-cigarettes exposure	6
European Food Safety Authority database for in vivo developmental neurotoxicity studies of pesticides	6
Correction	6
Correction	6
25X-NBOMe compounds – chemistry, pharmacology and toxicology. A comprehensive review	6
Diagnosis, toxicological mechanism, and detoxification for hepatotoxicity induced by pyrrolizidine alkaloids from herbal medicines or other plants	5
The effect of antioxidants on antineoplastic-induced male reproductive system damage: a systematic review of experimental studies	5
Necessary conditions for valid causal inference from observational data	5
Non-acute exposure of neonicotinoids, health risk assessment, and evidence integration: a systematic review	5
Mycotoxins occurrence in milk and cereals in North African countries – a review	5

Toxicity of chemical-based hand sanitizers on children and the development of natural alternatives: a computational approach	5
The formaldehyde dispute - Part A: acute and chronic inhalation toxicity and the evolution of scientific knowledge	5
Immunotoxicity of engineered nanomaterials and their role in asthma	4
A quantitative weight-of-evidence review of preclinical studies examining the potential developmental neurotoxicity of acetaminophen	4
A screening-level human health risk assessment of dietary intake of pesticide residues in produce as compared to consumer guide recommendations	4
Modeling the human placenta: in vitro applications in developmental and reproductive toxicology	4
Towards a science-based testing strategy to identify maternal thyroid hormone imbalance and neurodevelopmental effects in the progeny – Part IV: the ECETOC and CLE Proposal for a Thyroid Function-Rela	4
A systematic review of the epidemiology evidence on talc and cancer	4
Genotoxic and epigenetic signatures of early-life pesticide exposure: a systematic review and meta-analysis	4
Hazards of current concentration-setting practices in environmental toxicology studies	4
Improving interventional causal predictions in regulatory risk assessment	4
Molecular insights into the role of electronic cigarettes in oral carcinogenesis	4
A framework for integrating evidence to assess hazards and risk	4
The skin sensitization adverse outcome pathway: exploring the role of mechanistic understanding for higher tier risk assessment	4
Evaluation of the modes of action for key noncancer effects of 1,3-Butadiene: input from an independent expert panel to support derivation of data-derived extrapolation factors	4
Letter to the editor about the article “Weight of evidence evaluation for chemical-induced immunotoxicity for PFOA and PFOS: findings from an independent panel of experts” by Garvey et al. (2023)	4
Weight of evidence evaluation for chemical-induced immunotoxicity for PFOA and PFOS: findings from an independent panel of experts	4
The tradeoff between the efficacy of calcineurin inhibitors: prevention of allograft rejection vs. post-transplant renal and cardiovascular complications	4
Regulatory roles of extracellular vesicles in adverse pregnancy outcomes exposed with environmental toxicants	4