OOIR: Observatory of International Research

Papers

(The median citation count of Critical Reviews in Toxicology is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
What can we learn from epidemiological studies on chronic boron exposure?	79
Use and limitations of clinical data in the identification and classification of low molecular weight chemicals (LMWCs) as respiratory sensitizers: recommendations for improvement	67
Microbial degradation mechanisms, degradation pathways, and genetic engineering for pyrethroids: current knowledge and future perspectives	64
Perspectives on aerosol inhalability: concepts and applications	55
An examination of historical control histopathology metadata from 51 Amphibian Metamorphosis Assays	31
Mechanisms of developmental neurotoxicity mediated by perturbed thyroid hormone homeostasis in the brain: an adverse outcome pathway network	31
Overview of analytical methods for determining novel psychoactive substances, drugs and their metabolites in biological samples	26
Talc and human cancer: a systematic review of the experimental animal and mechanistic evidence	24
The environment and male reproductive system: the potential role and underlying mechanisms of cadmium in testis cancer	23
Exploring research gaps and trends in the management of acute phosphide poisoning: a systematic review	22
Evaluation of the human hazard of the liver and lung tumors in mice treated with permethrin based on mode of action	21
Identifying a reference list of respiratory sensitizers for the evaluation of novel approaches to study respiratory sensitization	20
Biomarkers for occupational manganese exposure	20
Molecular similarity in chemical informatics and predictive toxicity modeling: from quantitative read-across (q-RA) to quantitative read-across structure–activity relationship (q-RASAR) with the appli	20
Benzene metabolism and health risk evaluation: insights gained from biomonitoring	20
Does ozone inhalation cause adverse metabolic effects in humans? A systematic review	17
From cultivation to cancer: formation of N -nitrosamines and other carcinogens in smokeless tobacco and their mutagenic implications	17
25X-NBOMe compounds – chemistry, pharmacology and toxicology. A comprehensive review	16
Systematic review of epidemiological and toxicological evidence on health effects of fluoride in drinking water	14
Occupational exposure assessment with solid substances: choosing a vehicle for in vitro percutaneous absorption experiments	13
Temephos, an organophosphate larvicide for residential use: a review of its toxicity	13
Hydrogen sulfide poisoning in forensic pathology and toxicology: mechanism and metabolites quantification analysis	13
Dietary glycation compounds – implications for human health	13
Critical review and analysis of literature on low dose exposure to chemical mixtures in mammalian in vivo systems	13
A review of pulmonary neutrophilia and insights into the key role of neutrophils in particle-induced pathogenesis in the lung from animal studies of lunar dusts and other poorly soluble dust particles	13

Thank you to Reviewers for Critical Reviews in Toxicology	12
Mechanisms of neurodevelopmental toxicity of topiramate	12
The changing world of scientific publishing exemplified by Critical Reviews in Toxicology (1971 to 2021)	10
Fiber biodurability and biopersistence: historical toxicological perspective of synthetic vitreous fibers (SVFs), the long fiber paradigm, and implications for advanced materials	10
A quantitative weight-of-evidence review of preclinical studies examining the potential developmental and reproductive toxicity of acetaminophen	10
Consideration of the variability in control tumor incidence data at the Ramazzini Institute in evaluating treatment-related effects following chemical exposure	10
Hypothesis-driven weight of evidence evaluation indicates styrene lacks endocrine disruption potential	10
Thank you to authors and reviewers of papers in Critical Reviews in Toxicology (CRT) volume 53, 2023	10
Toxicity of bisphenol analogues on the reproductive, nervous, and immune systems, and their relationships to gut microbiome and metabolism: insights from a multi-species comparison	9
Potential application of probiotics in mycotoxicosis reduction in mammals and poultry	9
Potential airborne asbestos exposures in dentistry: a comprehensive review and risk assessment	9
Peptide reactivity assays for skin sensitisation – scope and limitations	9
Recent advances in electrochemical and optical sensing of the organophosphate chlorpyrifos: a review	9
Relevance of animal studies in the toxicological assessment of oil and wax hydrocarbons. Solving the puzzle for a new outlook in risk assessment	8
Tefluthrin: metabolism, food residues, toxicity, and mechanisms of action	8
Diagnosis, toxicological mechanism, and detoxification for hepatotoxicity induced by pyrrolizidine alkaloids from herbal medicines or other plants	7
Assessment of genotoxicity of glass ionomer cements: a systematic review	7
Nomograms applicability in clinical toxicology – enhancing precision in clinical decision-making: a systematic review	7
Incapacitating agents review: 20 years after Nord Ost Siege	7
International regulatory uses of acute systemic toxicity data and integration of new approach methodologies	7
Complex roles for sulfation in the toxicities of polychlorinated biphenyls	7
RNA A-to-I editing, environmental exposure, and human diseases	7
Toxicity of chemical-based hand sanitizers on children and the development of natural alternatives: a computational approach	7
Human chlorine gas exposition and its management – an umbrella review on human data	7
Towards a science-based testing strategy to identify maternal thyroid hormone imbalance and neurodevelopmental effects in the progeny – part II: how can key events of relevant adverse outcome pathways	7
Malathion or diazinon exposure and male reproductive toxicity: a systematic review of studies performed with rodents	6
Assessment of consumer exposure to boron in cleaning products: a case study of Canada	6
Response to the letter to the editor regarding the article “Weight of evidence evaluation for chemical-induced immunotoxicity for PFOA and PFOS: findings from an independent panel of experts” by Garve	6
Non-acute exposure of neonicotinoids, health risk assessment, and evidence integration: a systematic review	6
Letter to the editor, regarding the publication by Carrillo and colleagues, “Relevance of animal studies in the toxicological assessment of oil and wax hydrocarbons. Solving the puzzle for a new outlo	6
Pyrethroid based pesticides – chemical and biological aspects	6
An updated evaluation of reported no-observed adverse effect levels for chrysotile, amosite, and crocidolite asbestos for lung cancer and mesothelioma	6
Subject: call for papers–critical reviews in toxicology	5
Assessment of metal ion accumulation in oral mucosa cells of patients with fixed orthodontic treatment and cellular DNA damage: a systematic review	5
Comprehensive analysis of gastrointestinal side effects in COVID-19 patients undergoing combined pharmacological treatment with azithromycin and hydroxychloroquine: a systematic review and network met	5
Hepatotoxicity due to dietary supplements: state-of-the-art, gaps and perspectives	5
Mode of action of dieldrin-induced liver tumors: application to human risk assessment	5
The methodological rigour of systematic reviews in environmental health	5
Prevention and Detoxification of Mycotoxins in Human Food and Animal Feed using Bio-resources from South Mediterranean Countries: a Critical Review	5
Adverse outcome pathway (AOP): α2u-globulin nephropathy and kidney tumors in male rats	5
The tradeoff between the efficacy of calcineurin inhibitors: prevention of allograft rejection vs. post-transplant renal and cardiovascular complications	4
Procedural application of mode-of-action and human relevance analysis: styrene-induced lung tumors in mice	4
A risk assessment of mechanics who changed chrysotile asbestos containing brakes and other vehicle components in the 1950s–early 2000s era: an update on the 2004 evaluation	4
A review of mammalianin vivogenotoxicity of hexavalent chromium: implications for oral carcinogenicity risk assessment	4
Investigations on learning and memory function in extended one-generation reproductive toxicity studies – when considered needed and based on what?	4
Evaluating the conduct and reporting of the T-cell dependent antibody response in the Extended One-Generation Reproductive Toxicity study provided under the EU REACH regulation	4
EDC-induced mechanisms of immunotoxicity: a systematic review	3
A critical evaluation of rodent carcinogenicity studies on butyl methacrylate demonstrates a lack of carcinogenic potential	3
The effects of bisphenols on the cardiovascular system	3
Review of epidemiological and toxicological studies on health effects from ingestion of asbestos in drinking water	3

Mycotoxins occurrence in milk and cereals in North African countries – a review	3
Effects of BPA substitutes on the prenatal and cardiovascular systems	3
Examining the relationship between per-and polyfluoroalkyl substances and breast, colorectal, prostate, and ovarian cancers: a meta-analysis	3
Nephrotoxicity induced by natural compounds from herbal medicines – a challenge for clinical application	3
Clearance, biodistribution, and neuromodulatory effects of aluminum-based adjuvants. Systematic review and meta-analysis: what do we learn from animal studies?	3
Synthetic vitreous fibers (SVFs): adverse outcome pathways (AOPs) and considerations for next generation new approach methods (NAMs)	3
Critical evaluation of the human relevance of the mode of action for rodent liver tumor formation by activators of the constitutive androstane receptor (CAR)	3
Comprehensive analysis of the toxicity-related findings from repeated-dose subacute toxicity studies of industrial chemicals in male rats	3