OOIR: Observatory of International Research

Papers

(The median citation count of Bioconjugate Chemistry is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
Tailoring the Methods of Conjugation and Characterization for a Replication-Competent, Live, Viral Vector	246
Tyrosinase-Related Protein2 Peptide with Replacement of N-Terminus Residue by Cysteine Binds to H-2K^b and Induces Antigen-Specific Cytotoxic T Lymphocytes after Conjugation with CpG-DNA	152
A Cysteine-Maleimide-Based Design for Hemostatic, Antibacterial, and Biodegradable Wound Dressing	127
Cysteine-Targeting Gd-Based Spin Label and Its Application in Electron Paramagnetic Resonance Spectroscopy	99
PEGylation of anti-MerTK Antibody Modulates Ocular Biodistribution	78
Linker Chemistry and Connectivity Fine-Tune the Immune Response and Kinetic Solubility of Conjugated NOD2/TLR7 Agonists	66
Targeting HER2 with DNA Aptamers for Efficient Anticancer Drug Delivery: A Combined Experimental and Computational Study	57
Bioderived Lipoic Acid-Based Dynamic Covalent Nanonetworks of Poly(disulfide)s: Enhanced Encapsulation Stability and Cancer Cell-Selective Delivery of Drugs	53
Equimolar Cross-Coupling Using Reactive Coiled Coils for Covalent Protein Assemblies	52
Issue Editorial Masthead	47
Issue Publication Information	37
Issue Editorial Masthead	36
Issue Editorial Masthead	35
Solid-Phase Synthesis of Caged Luminescent Peptides via Side Chain Anchoring	34
Issue Publication Information	34
Xylose Dehydrogenase Immobilized on Ferromagnetic Nanoparticles for Bioconversion of Xylose to Xylonic Acid	34
Elucidating Critical Factors of Internalization and Drug Release of Antibody-Drug Conjugates (ADCs) Using Kinetic Parameters Evaluated by a Novel Tool Named TORCH	34
In Silico-Driven THIOMAB Approach for Stable PROTAC Conjugates by Docking Payloads in Antibody Cavities	30
Engineering and Validation of a Peptide-Stabilized Poly(lactic-co-glycolic) Acid Nanoparticle for Targeted Delivery of a Vascular Disruptive Agent in Cancer Therapy	30
Functionalization of Biomimetic Polydopamine Shells Constructed onto Bismuth-Core Particles for pH-Mediated Drug Targeting to Heal Bacterial Infections	30
Choice of an Optimal Modular Strategy for the Synthesis of DOTA-Containing Heterobivalent Agents Targeting PSMA and GRPr	30
Modular Adapters Utilizing Binders of Different Molecular Types Expand Cell-Targeting Options for Adenovirus Gene Delivery	30
Overcoming Synthetic Challenges and Evaluating in Vivo Efficacy of the MOG-Fc-Bifunctional Peptide Inhibitor for EAE in Mice	29
Efficiency and Safety of Dextran-PAMAM/siMMP-9 Complexes for Decreasing Matrix Metalloproteinase-9 Expression and Promoting Wound Healing in Diabetic Rats	29
Dimeric Metal-Salphen Complexes Which Target Multimeric G-Quadruplex DNA	29

Drug Delivery Targeting Neuroinflammation to Treat Brain Diseases	29
Enolate–Azide [3 + 2]-Cycloaddition Reaction Suitable for DNA-Encoded Library Synthesis	28
Issue Editorial Masthead	28
Targeted Polymersomes Enable Enhanced Delivery to Peripheral Nerves Post-Injury	27
Molecular Design Strategies Enabling Activity-Based Sensing and Labeling as a Platform for Probing Enzyme Activity, Redox Regulation, and Transition-Metal Signaling	27
A Modular Method for Rapidly Prototyping Targeted Gas Vesicle Protein Nanoparticles	26
Identification of a Novel Transasparaginase Activity of Bacillus subtilis (bTG) for Sequence-Specific Bioconjugation	26
Amphiphilic Polymeric Micelle Spherical Nucleic Acids (SNAs) as Drug Delivery Vehicles	25
Carbon Quantum Dots Synthesized from Quercetin: A Novel Approach for Potentiating the Antitumor Activity against Laryngeal Cancer Cells	24
Hollow Cobalt Sulfide Nanospheres with Highly Enzyme-like Antibacterial Activities to Accelerate Infected Wound Healing	24
Using Spectroscopy to Guide the Adaptation of Aptamers into Electrochemical Aptamer-Based Sensors	24
In Vacuo Glycation of Poly(l-Lysine): A Simple Method to Install Pendent Sugars	24
Computational Approaches for Antimicrobial Peptide Delivery	24
Luminescent Ruthenium(II) Complexes Used for the Detection of 8-Oxoguanine in the Human Telomeric Sequence	23
TfR1-Binding Peptide Conjugation Facilitates Robust and Specific siRNA Delivery to the Central Nervous System	23
A Universal and Modular Scaffold for Heparanase Activatable Probes and Drugs	23
Redesigning Ibuprofen for Improved Oral Delivery and Reduced Side Effects	23
“Zip-to-Cytosol”: Glutathione-Cleavable Fluorinated Polyplexes Deliver siRNA at Single-Digit Nanomolar Dose with >90% Gene Silencing	22
Revival of Bioengineered Proteins as Carriers for Nucleic Acids	22
Effect of Carrier Protein Size on Hapten Immunogenicity and Antibody Affinity in Mice	22
Squaramide Formation for DNA-Encoded Library Synthesis	21
Cascade-Responsive Zwitterionic Polyprodrugs Leverage Fast Transcytosis for Deep Tumor Penetration and Intracellular Drug Release	21
Probing the Broad-Spectrum Virus-Neutralizing Epitopes Using the High-Density Oligomannose-Conjugates and Carbohydrate Microarrays	21
Systematic Evaluation of Maleimide Spacer Impact on Drug-Linker Deconjugation in Antibody-Drug Conjugates Ex Vivo and In Vivo	21
DNA Modifications Enabling Proximity Biotinylation	21
Multisite Labeling of Proteins Using the Ligand-Directed Reactivity of Triggerable Michael Acceptors	21
Lipidated Aminoglycosides as New Tools that Repurpose Old Natural Antibiotics for New-Fangled Utility	21
Multivalent Display of Erythropoietin on Quantum Dots Enhances Aquaporin-4 Expression and Water Transport in Human Astrocytes In Vitro	21
Site-Specific Molecular Engineering of Nanobody–Glucoside Conjugates for Enhanced Brain Tumor Targeting	20
Dual-Function Antibody Conjugate-Enabled Photoimmunotherapy Complements Fluorescence and Photoacoustic Imaging of Head and Neck Cancer Spheroids	20
Clickable and Degradable Polycarbonate Vehicles for mRNA Delivery	20
Enzymatic Cellular Nanoparticles Deliver Payloads across Mucosal Barriers	19
Biocatalytic Clusterzyme Patches Restore Lung Function via Immunomodulation and Mitochondria Protection	19
Receptor-Mediated Transmembrane Activation of Protein Folding in Synthetic Cells	19
Azidocoumarin Glycan Probes for Photoinduced Cross-Linking and In Situ Fluorescent Labeling	19
Efficient Inhibition of TGF-β Signaling via Cytosolic Delivery of a Smad2/3-Binding Peptide Using the Cell-Penetrating PG-Surfactant DKDKC	19
Kaempferol–Iron Assembled Nanoparticles for Synergistic Photothermal and Chemodynamic Therapy of Breast Cancer	19
Single Gold Nanostars Achieve Inherent Cascade Catalytic and Near-Infrared Photothermal Activities for Efficient Tumor Therapy	19
Issue Editorial Masthead	18
Effect of Lipidation on the Structure, Oligomerization, and Aggregation of Glucagon-like Peptide 1	18
Advances in the Treatment of Spinal Cord Injury with Nanozymes	18
7-Deaza-2′-deoxyisoguanosine, a Noncanonical Nucleoside for Nucleic Acid Code Expansion and New DNA Constructs: Nucleobase Functionalization of Inverse Watson–Crick and Purine–Purine Base Pairs	18
Issue Editorial Masthead	18
Bioconjugate Chemistry: Enabling Innovation and Fostering Community at the Nexus of Synthetic and Biological Research	18
Targeted Protein Degradation (TPD) for Immunotherapy: Understanding Proteolysis Targeting Chimera-Driven Ubiquitin-Proteasome Interactions	17
Polyfluoroalkyl Tag Decoration Enables Significantly Enhanced Tumor Penetration Ability of a PTK7 Targeting Aptamer	17
A New Class of Tunable Acid-Sensitive Linkers for Native Drug Release Based on the Trityl Protecting Group	17
Antibody Engineering for Receptor-Mediated Transcytosis Across the Blood–Brain Barrier	17
Recent Advances in Nanoimmunotherapy by Modulating Tumor-Associated Macrophages for Cancer Therapy	17
Functional Bioimaging Probes: Fluorescent Conjugated Polymer Nanoparticles Coupled with Pleural Fluid-Derived Peptides and Proteins	17

A Switch-On Affinity-Based Iridium(III) Conjugate Probe for Imaging Mitochondrial Glutathione S-Transferase in Breast Cancer Cells	17
Lectin-Functionalized Chitosan Nanoparticle-Based Biosensor for Point-of-Care Detection of Bacterial Infections	17
Tyrosinase-Mediated Conjugation for Antigen Display on Ferritin Nanoparticles	17
Biophysical and Biochemical Characterization of PEGylated High-Molecular-Weight Relaxed and Tense Quaternary State Polymerized Human Hemoglobin	17
Discovery of a Novel ADC for Multifunctional Theranostics: From Vascular Normalization to Synergistic Therapy	16
Resveratrol Carbon Dots Disrupt Mitochondrial Function in Cancer Cells	16
Structure–Activity Relationships of Antibody-Drug Conjugates: A Systematic Review of Chemistry on the Trastuzumab Scaffold	16
Live-Cell Imaging of the Binding between a Chemical Drug and Its Target Proteins Based on Intracellular Redistribution of the Target Proteins	16
A Genetically Encoded Photocaged Cysteine for Facile Site-Specific Introduction of Conjugation-Ready Thiol Residues in Antibodies	16
Poly(malic acid) Nanoconjugates of Pyrazinoic Acid for Lung Delivery in the Treatment of Tuberculosis	16
From Cloudy to Clear: A Strategy to Resolve the Complex Structural Elucidation of Bicycle Drug Conjugate Zelenectide Pevedotin by NMR	16
Cytokine Biopharmaceuticals with “Activity-on-Demand” for Cancer Therapy	16
Preparation, In Vitro Affinity, and In Vivo Biodistribution of Receptor-Specific ⁶⁸Ga-Labeled Peptides Targeting Vascular Endothelial Growth Factor Receptors	16
Modulation of Membrane-Disruptive Activity of Melittin via N- and C-Terminal PEGylation Strategies	16
Introducing TAPY as a Versatile Alternative to TPP for Selective Mitochondrial Targeting in Cancer Cells	15
Rapid Access to Potent Bispecific T Cell Engagers Using Biogenic Tyrosine Click Chemistry	15
Rational Design of Targeted Gold Nanoclusters with High Affinity to Integrin αvβ3 for Combination Cancer Therapy	15
MT1-MMP-Targeted Photoimmunotherapy via an IR700-Conjugated Bicyclic Peptide	15
Photoactivated Nanohybrid for Dual-Nuclei MR/US/PA Multimodal-Guided Photothermal Therapy	15
Lysine-Derived Charge-Altering Releasable Transporters: Targeted Delivery of mRNA and siRNA to the Lungs	15
Protein Corona Formation on Lipid Nanoparticles Negatively Affects the NLRP3 Inflammasome Activation	15
Peptide-Based PROTACs: Transitioning from Static Paradigm to a Dynamic Landscape within Targeted Protein Degradation	14
Asymmetry of Dual-Display DNA-Encoded Chemical Libraries	14
Effect of Click Chemistry Linkages on the Biological Behavior of Albumin-Binding ¹⁷⁷Lu-DOTAGA-pIBA-LLP2A Analogues Targeting Melanoma	14
Genetic Determinants of Surface Accessibility in Staphylococcus aureus	14
Development of a Decafluorobiphenyl Cyclized Peptide Targeting the NEMO–IKKα/β Interaction that Enhances Cell Penetration and Attenuates Lipopolysaccharide-Induced Acute Lung Injury	14
Long-Acting Poly(ADP-ribose) Polymerase Inhibitor Prodrug for Humans	14
Click Chemistry Enables [⁸⁹Zr]Zr-DOTA Radioimmunoconjugation for Theranostic ⁸⁹Zr-immunoPET	14
Synthetic and Computational Design Insights toward Mimicking Protein Binding of Phosphate	14
Issue Publication Information	14
Coelenterazine Analog Library for Specific Imaging of Serum Albumins on Conventional and Paper Microplates	14
A Novel Family of Acid-Cleavable Linker Based on Cyclic Acetal Motifs for the Production of Antibody-Drug Conjugates with High Potency and Selectivity	14
Potential Nucleotide Sites for RNA Glycosylation: acp3U and Beyond	14
Ugi-Type Reaction Enables Access to Fused Imidazole Derivatives for DNA-Encoded Library Technology	14
Noninvasive Analysis of Peptidoglycan from Living Animals	14
pH-Responsive Amphiphilic Triblock Fluoropolymers as Assemble Oxygen Nanoshuttles for Enhancing PDT against Hypoxic Tumor	13
Photoactivatable Liposomes for Blue to Deep Red Light-Activated Surface Drug Release: Application to Controlled Delivery of the Antitumoral Drug Melphalan	13
Lipophilic Anchors that Embed Bioconjugates in Bilayer Membranes: A Review	13
ProtFPreDTI: Drug–Target Interaction Prediction Study and LIME Interpretability Analysis Based on the ProtBERT Deep Language Model with Adaptive Fuzzy Sampling Strategy	13
Human Behavior-Inspired Linchpin-Directed Catalysis for Traceless Precision Labeling of Lysine in Native Proteins	13
Enhancing Enzymatic Bioconjugation Efficiency via Computer-Based Installation of a Substrate Recruitment Domain	13
Issue Publication Information	13
Chemistry of DNA Nanotechnology Special Issue	13
NIR-Triggered On-Demand Nitric Oxide Release for Enhanced Synergistic Phototherapy of Hypoxic Tumor	13
Precise Manipulation of the Site and Stoichiometry of Capsid Modification Enables Optimization of Functional Adeno-Associated Virus Conjugates	13
Aptamer-Functionalized AuNR Nanoplatform for Active Targeted Chemo-Photothermal Therapy of Tumor	13
Optogenetic Tools for Spatiotemporal Interrogation of Cytoskeletal Dynamics	13
Mechanistic Characterization of the Potency of THIOMAB Antibody–Drug Conjugates Targeting Staphylococcus aureus and ETbR-Expressing Tumor Cells Using Qua	13
Metal-Free Click-Chemistry: A Powerful Tool for Fabricating Hydrogels for Biomedical Applications	13
Miniaturized Synthetic Palmitoylation Motifs for Small-Molecule Localization in Living Cells	13
Synthesis of Cyclic Glycopolymers Presenting Sialyllactose Derivatives Toward Siglec-Mediated Signal Suppression	13
Light-Activated Molecular Purification (LAMP) of Recombinant Proteins	13
Sensitive Detection of the Human Epididymis Protein-4 (HE4) Ovarian Cancer Biomarker through a Sandwich-Type Immunoassay Method with Laser-Induced Breakdown Spectroscopy	13
Metabolic GLUT1 Priming with Disulfide-Stabilized Micelles Enables Noninvasive mRNA Delivery across the Blood–Brain Barrier	13
Bypassing the Need for Cell Permeabilization: Nanobody CDR3 Peptide Improves Binding on Living Bacteria	13
Fluorescence-Based Simple and Practical Assay Method for DNA Damage Analysis in DNA-Encoded Library Synthesis	13
Conceptualization and Preliminary Characterization of Poloxamer-Based Hydrogels for Biomedical Applications	13
Phosphorothioate-Modified DNA Aptamer-Based PROTACs for Targeted Degradation of Estrogen Receptor α	13
Synthesis and Biological Evaluation of Bile Acid–Triclosan Conjugates: A Study on Antibacterial, Antibiofilm, and Molecular Docking	12
Matrix Metalloproteinase-Responsive Drug Delivery Systems	12
Self-Assembly of the Tetraphenylethylene-Capped Diserine through a Hierarchical Assembly Process	12
Modular Display of Plasmodium yoelii Circumsporozoite Surface Protein and Merozoite Surface Protein-1 on Norovirus-like Particles	12
A Simple and Versatile Strategy for Oriented Immobilization of His-Tagged Proteins on Magnetic Nanoparticles	12
Radiation Cleaved Drug-Conjugate Linkers Enable Local Payload Release	12
Molecular Design Strategies of Fluorescence Probes with Long-Term Membrane Retention for Plasma Membrane Dynamics Imaging	12
Developing and Characterizing the Tumor-Targeting Efficiency of an Anti-EphA2-CD11b Bispecific Antibody	12
An Enzyme-Responsive Imiquimod Prodrug for Precision Immune Activation within the Tumor Microenvironment	11
Crossing the Solubility Rubicon: 15-Crown-5 Facilitates the Preparation of Water-Soluble Sulfo-NHS Esters in Organic Solvents	11
Development of a Long-Acting Myeloid-Derived Growth Factor via Site-Specific PEGylation	11
Synthetic Multivalent Tn Antigen Elicits Valency-Dependent IgG Antibody Production	11
RGD and Scutellarin Conjugate (WK001) Targeting Platelet Glycoprotein IIb/IIIa Receptor Protects from Myocardial Ischemia/Reperfusion Injury: Synthesis, Characterization, and Bioactivity Evaluation	11
Point-of-Care Testing for Norovirus Typing Using CRISPR/Cas12a Combined with Reverse Transcription Recombinase Polymerase Amplification	11
Carbon Dots as Potential Therapeutic Agents for Treating Non-Alcoholic Fatty Liver Disease and Associated Inflammatory Bone Loss	11
Harnessing Fc-Directed Bioconjugation for the Synthesis of Site-Specifically Modified Radioimmunoconjugates	11
Issue Publication Information	11
Multilayer Fluorescent Immunoassay for Early and Sensitive Dengue Virus Detection Using Host and Viral Biomarkers	11
Dual-Boronic Acid Reagents That Combine Dynamic and Covalent Bioconjugation	11
Fluorophore Labeling of Proteins: a Versatile Trigger–Release–Conjugation Platform Based on the Quinone Methide Chemistry	11
Targeted NIR Fluorescent Mechanically Interlocked Molecules-Peptide Bioconjugate for Live Cancer Cells Submitochondrial Stimulated Emission Depletion Super-Resolution Microscopy	11
Photochemical-Promoted Cross-Coupling Reaction of Alkyl Boronate Esters with DNA-Conjugated Aryl Bromides for DNA-Encoded Library Synthesis	11

Customizable Click Biochemistry Strategy for the Design and Preparation of Glucagon-like Peptide-1 Conjugates and Coagonists	11
One-Step Conversion of NHS Esters to Reagents for Site-Directed Labeling of IgG Antibodies	11
Synergism of ⁶⁴Cu-Labeled RGD with Anti-PD-L1 Immunotherapy for the Long-Acting Antitumor Effect	11
Engineering a High-Affinity Anti-Methoxy Poly(ethylene glycol) (mPEG) Antibody for Sensitive Immunosensing of mPEGylated Therapeutics and mPEG Molecules	11
Dynamic Catalysis Guided by Nucleic Acid Networks and DNA Nanostructures	11
Sustained Releasable Copper and Zinc Biogenic Ions Co-Assembled in Metal–Organic Frameworks Reinforced Bacterial Eradication and Wound Mitigation in Diabetic Mice	11
Quantum Dot Erythropoietin Bioconjugates Enhance EPO-Receptor Clustering on Transfected Human Embryonic Kidney Cells	11
Issue Publication Information	10
Linker and Conjugation Site Synergy in Antibody–Drug Conjugates: Impacts on Biological Activity	10
Solid-Phase Collateral Cleavage System Based on CRISPR/Cas12 and Its Application toward Facile One-Pot Multiplex Double-Stranded DNA Detection	10
Large Protein Assemblies for High-Relaxivity Contrast Agents: The Case of Gadolinium-Labeled Asparaginase	10
Mirror-Image Single-Domain Antibody for a Novel Nonimmunogenic Drug Scaffold	10
Design and Optimization of an α-Helical Bundle Dimer Cell-Penetrating Peptide for In Vivo Drug Delivery	10
Issue Publication Information	10
Persistent Luminescence Nanoparticle-Based Biosensors	10
IgG-Binding Nanobody Capable of Prolonging Nanobody-Based Radiotracer Plasma Half-Life and Enhancing the Efficacy of Tumor-Targeted Radionuclide Therapy	10
HOCl-Activated Reactive Organic Selenium Delivery Platform for Alleviation of Inflammation	10
Harnessing DNA Nanotechnology and Chemistry for Applications in Photonics and Electronics	10
pH/ROS Dual-Responsive Self-Amplified ROS-Replenishing Self-Delivery Systems for Tumor-Specific Chemotherapy/Ferroptosis	10
Issue Editorial Masthead	10
Aptamer- vs Fab-Conjugated Liposomes: A Comparative Study in Targeting Acute Myeloid Leukemia Cells	10
Synthesis of DNA-Encoded Bicyclic Peptides via Cysteine-Promoted Cyclization and Amide Condensation Reaction	10
Cyclopentadiene as a Multifunctional Reagent for Normal- and Inverse-Electron Demand Diels–Alder Bioconjugation	10
Formal [4 + 2] Cycloadditions of Maleimides on Duplex DNA	10
Live-Cell Mitochondrial Targeted NIR Fluorescent Covalent Labeling of Specific Proteins Using a Dual Localization Effect	10
Modular PET Agent Construction Strategy through Strain-Promoted Double-Click Reagent with Efficient Photoclick Step	10
Bioreducible Amphiphilic Hyperbranched Polymer-Drug Conjugate for Intracellular Drug Delivery	10
Covalent and Oriented Immobilization of Antibodies through Systematic Modification of Photoactivatable RNA Hybrid Aptamers	10
Synthetic Amine Linkers for Efficient Sortagging	10
Targeted Delivery of TLR7 Agonists to the Tumor Microenvironment Enhances Tumor Immunity via Activation of Tumor-Resident Myeloid Cells	10
Developing ⁶⁸ Ga-Labeled Exendin(9–39) Derivatives for PET Imaging of Insulinomas	10
Synthesis and Evaluation of Three Azide-Modified Disaccharide Oxazolines as Enzyme Substrates for Single-Step Fc Glycan-Mediated Antibody-Drug Conjugation	10
Tumor-Derived PD-L1⁺ Exosomes with Natural Inflammation Tropism for Psoriasis-Targeted Treatment	10
Novel Type-I Carbazole/Benz[cd]indolium Photosensitizers for High-Efficient Chemo/Photodynamic/Immune Multimodal Therapy of Hypoxic Tumor	10
Azobenzene-Based Amino Acids for the Photocontrol of Coiled-Coil Peptides	10
Generation of Multivalent Nanobody-Based Proteins with Improved Neutralization of Long α-Neurotoxins from Elapid Snakes	10
Issue Publication Information	10
Cationic Micelles Outperform Linear Polymers for Delivery of Antisense Oligonucleotides in Serum: An Exploration of Polymer Architecture, Cationic Moieties, and Cell Addition Order	9
Issue Publication Information	9
Multivalent Cucurbituril Dendrons for Cell Membrane Engineering with Supramolecular Receptors	9
On-Resin DIAMSAR-Conjugated CD38-Targeted Peptides and Their Inverso and Dimeric-Inverso Analogs for PET Imaging of Multiple Myeloma	9
Lysosome-Specific Delivery of β-Glucosidase Enzyme Using Protein-Glycopolypeptide Conjugate via Protein Engineering and Bioconjugation	9
Binary Copolymer Blending Enhances pDNA Delivery Performance and Colloidal Shelf Stability of Quinine-Based Polyplexes	9
Issue Publication Information	9
Lipid Nanoparticles for Brain Tumor Theranostics: Challenges and Status	9
Issue Publication Information	9
Issue Editorial Masthead	9
Rapid Covalent Labeling of Membrane Proteins on Living Cells Using a Nanobody–Epitope Tag Pair	9
Design of a Pan-Tumor Fluorescence Imaging Cocktail for Fluorescence-Guided Surgery	9
Chemo-Enzymatic Synthesis of Viscoelastic Pseudopeptidoglycan Networks	9
Issue Editorial Masthead	9
Light-Activated Nanodiamond-Based Drug Delivery Systems for Spatiotemporal Release of Antisense Oligonucleotides	9
Issue Editorial Masthead	9
Development of a Mesothelin-Binding Engineered Scaffold Protein as a Theranostic for Pleural Mesothelioma	9
Construction of Self-Assembling Lipopeptide-Based Benign Nanovesicles to Prevent Amyloid Fibril Formation and Reduce Cytotoxicity of GxxxGxxxGxxxG Motif	9
Issue Editorial Masthead	9
Mitigating Cannabidiol’s Non-Selective Cytotoxicity via Subcellular Organelle Targeting: Exploring Mitochondrial Targeting Potential	9
New Triazacycloalkane Derivatives as Cytotoxic Agents for CLL Treatment: From Proof of Concept to the Targeting Biomolecule	9
Stearylated Macropinocytosis-Inducing Peptides Facilitating the Cellular Uptake of Small Extracellular Vesicles	9
Issue Editorial Masthead	9
Cationic Peptide Conjugation Enhances Intratumoral Retention and Antitumor Efficacy of Immune Checkpoint Blockade Antibodies	9
Transferrin Receptor-Targeted Aptamer–Drug Conjugate Overcomes Blood–Brain Barrier for Potent Glioblastoma Therapy	9
iFLinkC-X: A Scalable Framework to Assemble Bespoke Genetically Encoded Co-polymeric Linkers of Variable Lengths and Amino Acid Composition	9
Diligent Design Enables Antibody-ASO Conjugates with Optimal Pharmacokinetic Properties	9
Engineering the Propeptide of Microbial Transglutaminase Zymogen: Enabling Substrate-Dependent Activation for Bioconjugation Applications	9
H₃TPAN-Triazole-Bn-NH₂: Tripicolinate Clicked-Bifunctional Chelate for [²²⁵Ac]/[¹¹¹In] Theranostics	9
Synthesis of 5′-Thiol Functionalized Morpholino Oligo-Nucleotide and Subsequent Conjugation with IGT to Improve Delivery and Antisense Efficacy In Vitro	9
Correction to “In Vivo Interrogation of Cell-Penetrating Peptide Function: Accumulation in Tumors and the Potential as a Specific PET Probe”	9
Carbonic Anhydrase IX Targeting Mn(II)-Based Magnetic Resonance Molecular Imaging Probe for Hypoxia Tumors	9
Light-Controlled Promiscuous Cell Adhesion through the Plasma Membrane-Binding Protein BcLOV4	9
Intravenous Hemostats: Foundation, Targeting, and Controlled-Release	8
AUNP-12 Near-Infrared Fluorescence Probes across NIR-I to NIR-II Enable In Vivo Detection of PD-1/PD-L1 Axis in the Tumor Microenvironment	8
Issue Editorial Masthead	8
Dynamics of DNA Origami Lattices	8
In Vivo Comparative Study of Radioiodinated Folate Receptor Targeting Albumin Probes for Atherosclerosis Plaque Imaging	8
Issue Publication Information	8
Gastrodin Liposomes Block Crosstalk between Astrocytes and Glioma Cells via Downregulating Cx43 to Improve Antiglioblastoma Efficacy of Temozolomide	8
Correction to “Oriented Antibody Coupling to an Antifouling Polymer Using Glycan Remodeling for Biosensing by Particle Motion”	8
Issue Publication Information	8
Superresolution Imaging with Single-Antibody Labeling	8
RPA-CRISPR-Cas-Mediated Dual Lateral Flow Assay for the Point-of-Care Testing of HPV16 and HPV18	8
Click Chemistry: Reaction Rates and Their Suitability for Biomedical Applications	8
Enhanced ASO-Mediated Gene Silencing with Lipophilic pH-Responsive Micelles	8
Issue Editorial Masthead	8
Facile Synthesis of Rigid Binuclear Manganese Complexes for Magnetic Resonance Angiography and SLC39A14-Mediated Hepatic Imaging	8
Advancing the Utility of DNA Origami Technique through Enhanced Stability of DNA-Origami-Based Assemblies	8
Thymidine Phosphodiester Chemiluminescent Probe for Sensitive and Selective Detection of Ectonucleotide Pyrophosphatase 1	8
The Base Pairs of Isoguanine and 8-Aza-7-deazaisoguanine with 5-Methylisocytosine as Targets for DNA Functionalization	8
One-Pot, One-Step Synthesis of Drug-Loaded Magnetic Multimicelle Aggregates	8
Application of N-Terminal Site-Specific Biotin and Digoxigenin Conjugates to Clinical Anti-drug Antibody Assay Development	8
Biomaterial-Mediated Exogenous Facile Coating of Natural Killer Cells for Enhancing Anticancer Efficacy toward Hepatocellular Carcinoma	8
Mitochondria-Targeting Antimicrobial Peptide (AMP) Regulating N6-Methyladenosine (m6A) Modification to Promote Colon Cancer Ferroptosis	8
A Dual-Targeted Fluorescent Probe with a Semicurcumin Structure for Imaging β-Amyloid and α-Synuclein Aggregates	8
Issue Editorial Masthead	8
Site-Specific Conjugation of Native Antibody: Transglutaminase-Mediated Modification of a Conserved Glutamine While Maintaining the Primary Sequence and Core Fc Glycan via Trimming with an Endoglycosi	8