OOIR: Observatory of International Research

Papers

(The TQCC of Bioconjugate Chemistry is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-12-01 to 2025-12-01.)

Article	Citations
Tailoring the Methods of Conjugation and Characterization for a Replication-Competent, Live, Viral Vector	186
Targeting HER2 with DNA Aptamers for Efficient Anticancer Drug Delivery: A Combined Experimental and Computational Study	150
Linker Chemistry and Connectivity Fine-Tune the Immune Response and Kinetic Solubility of Conjugated NOD2/TLR7 Agonists	127
Tyrosinase-Related Protein2 Peptide with Replacement of N-Terminus Residue by Cysteine Binds to H-2K^b and Induces Antigen-Specific Cytotoxic T Lymphocytes after Conjugation with CpG-DNA	87
A Cysteine-Maleimide-Based Design for Hemostatic, Antibacterial, and Biodegradable Wound Dressing	77
Cysteine-Targeting Gd-Based Spin Label and Its Application in Electron Paramagnetic Resonance Spectroscopy	74
PEGylation of anti-MerTK Antibody Modulates Ocular Biodistribution	63
Equimolar Cross-Coupling Using Reactive Coiled Coils for Covalent Protein Assemblies	62
Identification of a Novel Transasparaginase Activity of Bacillus subtilis (bTG) for Sequence-Specific Bioconjugation	58
Issue Editorial Masthead	52
Issue Publication Information	43
Issue Editorial Masthead	41
Issue Editorial Masthead	39
Issue Publication Information	37
In Silico-Driven THIOMAB Approach for Stable PROTAC Conjugates by Docking Payloads in Antibody Cavities	36
Elucidating Critical Factors of Internalization and Drug Release of Antibody-Drug Conjugates (ADCs) Using Kinetic Parameters Evaluated by a Novel Tool Named TORCH	36
Xylose Dehydrogenase Immobilized on Ferromagnetic Nanoparticles for Bioconversion of Xylose to Xylonic Acid	34
Engineering and Validation of a Peptide-Stabilized Poly(lactic-co-glycolic) Acid Nanoparticle for Targeted Delivery of a Vascular Disruptive Agent in Cancer Therapy	34
Dimeric Metal-Salphen Complexes Which Target Multimeric G-Quadruplex DNA	34
Choice of an Optimal Modular Strategy for the Synthesis of DOTA-Containing Heterobivalent Agents Targeting PSMA and GRPr	32
Designing Functional Bionanoconstructs for Effective In Vivo Targeting	31
RGD-Modified Titanium as an Improved Osteoinductive Biomaterial for Use in Dental and Orthopedic Implants	30
Targeted Polymersomes Enable Enhanced Delivery to Peripheral Nerves Post-Injury	30
Evaluation of Cellular Targeting by Fab′ vs Full-Length Antibodies in Antibody–Nanoparticle Conjugates (ANCs) Using CD4 T-cells	28
Modular Adapters Utilizing Binders of Different Molecular Types Expand Cell-Targeting Options for Adenovirus Gene Delivery	28

Functionalization of Biomimetic Polydopamine Shells Constructed onto Bismuth-Core Particles for pH-Mediated Drug Targeting to Heal Bacterial Infections	28
A Series of Furimazine Derivatives for Sustained Live-Cell Bioluminescence Imaging and Application to the Monitoring of Myogenesis at the Single-Cell Level	27
Overcoming Synthetic Challenges and Evaluating in Vivo Efficacy of the MOG-Fc-Bifunctional Peptide Inhibitor for EAE in Mice	27
Bioderived Lipoic Acid-Based Dynamic Covalent Nanonetworks of Poly(disulfide)s: Enhanced Encapsulation Stability and Cancer Cell-Selective Delivery of Drugs	26
Efficiency and Safety of Dextran-PAMAM/siMMP-9 Complexes for Decreasing Matrix Metalloproteinase-9 Expression and Promoting Wound Healing in Diabetic Rats	26
Solid-Phase Synthesis of Caged Luminescent Peptides via Side Chain Anchoring	25
Enolate–Azide [3 + 2]-Cycloaddition Reaction Suitable for DNA-Encoded Library Synthesis	25
Drug Delivery Targeting Neuroinflammation to Treat Brain Diseases	24
Hollow Cobalt Sulfide Nanospheres with Highly Enzyme-like Antibacterial Activities to Accelerate Infected Wound Healing	24
Enzymatic Cellular Nanoparticles Deliver Payloads across Mucosal Barriers	24
Squaramide Formation for DNA-Encoded Library Synthesis	24
In Vacuo Glycation of Poly(l-Lysine): A Simple Method to Install Pendent Sugars	23
A Universal and Modular Scaffold for Heparanase Activatable Probes and Drugs	23
Clickable and Degradable Polycarbonate Vehicles for mRNA Delivery	23
TfR1-Binding Peptide Conjugation Facilitates Robust and Specific siRNA Delivery to the Central Nervous System	22
Luminescent Ruthenium(II) Complexes Used for the Detection of 8-Oxoguanine in the Human Telomeric Sequence	22
Redesigning Ibuprofen for Improved Oral Delivery and Reduced Side Effects	22
Multisite Labeling of Proteins Using the Ligand-Directed Reactivity of Triggerable Michael Acceptors	22
Single Gold Nanostars Achieve Inherent Cascade Catalytic and Near-Infrared Photothermal Activities for Efficient Tumor Therapy	22
Biocatalytic Clusterzyme Patches Restore Lung Function via Immunomodulation and Mitochondria Protection	22
Effect of Lipidation on the Structure, Oligomerization, and Aggregation of Glucagon-like Peptide 1	21
DNA Modifications Enabling Proximity Biotinylation	21
Kaempferol–Iron Assembled Nanoparticles for Synergistic Photothermal and Chemodynamic Therapy of Breast Cancer	21
Probing the Broad-Spectrum Virus-Neutralizing Epitopes Using the High-Density Oligomannose-Conjugates and Carbohydrate Microarrays	21
Exo-Enzymatic Cell-Surface Glycan Labeling for Capturing Glycan–Protein Interactions through Photo-Cross-Linking	21
Dual-Function Antibody Conjugate-Enabled Photoimmunotherapy Complements Fluorescence and Photoacoustic Imaging of Head and Neck Cancer Spheroids	21
Artificial Nanocage Formed via Self-Assembly of β-Annulus Peptide for Delivering Biofunctional Proteins into Cell Interiors	20
Multivalent Display of Erythropoietin on Quantum Dots Enhances Aquaporin-4 Expression and Water Transport in Human Astrocytes In Vitro	20
Site-Specific Molecular Engineering of Nanobody–Glucoside Conjugates for Enhanced Brain Tumor Targeting	20
Receptor-Mediated Transmembrane Activation of Protein Folding in Synthetic Cells	20
Advances in the Treatment of Spinal Cord Injury with Nanozymes	19
Issue Editorial Masthead	19
Computational Approaches for Antimicrobial Peptide Delivery	19
Introducing TAPY as a Versatile Alternative to TPP for Selective Mitochondrial Targeting in Cancer Cells	19
Issue Editorial Masthead	19
Using Spectroscopy to Guide the Adaptation of Aptamers into Electrochemical Aptamer-Based Sensors	19
Revival of Bioengineered Proteins as Carriers for Nucleic Acids	19
Poly(malic acid) Nanoconjugates of Pyrazinoic Acid for Lung Delivery in the Treatment of Tuberculosis	19
Polyfluoroalkyl Tag Decoration Enables Significantly Enhanced Tumor Penetration Ability of a PTK7 Targeting Aptamer	18
Discovery of a Novel ADC for Multifunctional Theranostics: From Vascular Normalization to Synergistic Therapy	18
Radiotracers for Nuclear Imaging of Reactive Oxygen Species: Advances Made So Far	18
7-Deaza-2′-deoxyisoguanosine, a Noncanonical Nucleoside for Nucleic Acid Code Expansion and New DNA Constructs: Nucleobase Functionalization of Inverse Watson–Crick and Purine–Purine Base Pairs	18
Antibody Engineering for Receptor-Mediated Transcytosis Across the Blood–Brain Barrier	18
Rapid Copper-free Click Conjugation to Lipid-Shelled Microbubbles for Ultrasound Molecular Imaging of Murine Bowel Inflammation	18
Bioconjugate Chemistry: Enabling Innovation and Fostering Community at the Nexus of Synthetic and Biological Research	18
Recent Advances in Nanoimmunotherapy by Modulating Tumor-Associated Macrophages for Cancer Therapy	18
Functional Bioimaging Probes: Fluorescent Conjugated Polymer Nanoparticles Coupled with Pleural Fluid-Derived Peptides and Proteins	17
Comparison of Quenching Efficiencies in Long Triple-Labeled and Double-Labeled TaqMan Oligodeoxynucleotide Probes	17
Cytokine Biopharmaceuticals with “Activity-on-Demand” for Cancer Therapy	17
Tyrosinase-Mediated Conjugation for Antigen Display on Ferritin Nanoparticles	17

A Genetically Encoded Photocaged Cysteine for Facile Site-Specific Introduction of Conjugation-Ready Thiol Residues in Antibodies	17
Rapid Access to Potent Bispecific T Cell Engagers Using Biogenic Tyrosine Click Chemistry	17
Structure–Activity Relationships of Antibody-Drug Conjugates: A Systematic Review of Chemistry on the Trastuzumab Scaffold	17
Biophysical and Biochemical Characterization of PEGylated High-Molecular-Weight Relaxed and Tense Quaternary State Polymerized Human Hemoglobin	17
Modulation of Membrane-Disruptive Activity of Melittin via N- and C-Terminal PEGylation Strategies	17
A New Class of Tunable Acid-Sensitive Linkers for Native Drug Release Based on the Trityl Protecting Group	17
Protein Corona Formation on Lipid Nanoparticles Negatively Affects the NLRP3 Inflammasome Activation	16
Targeted Protein Degradation (TPD) for Immunotherapy: Understanding Proteolysis Targeting Chimera-Driven Ubiquitin-Proteasome Interactions	16
Live-Cell Imaging of the Binding between a Chemical Drug and Its Target Proteins Based on Intracellular Redistribution of the Target Proteins	16
Rational Design of Targeted Gold Nanoclusters with High Affinity to Integrin αvβ3 for Combination Cancer Therapy	16
Photoactivated Nanohybrid for Dual-Nuclei MR/US/PA Multimodal-Guided Photothermal Therapy	16
Lysine-Derived Charge-Altering Releasable Transporters: Targeted Delivery of mRNA and siRNA to the Lungs	16
Preparation, In Vitro Affinity, and In Vivo Biodistribution of Receptor-Specific ⁶⁸Ga-Labeled Peptides Targeting Vascular Endothelial Growth Factor Receptors	16
A Novel Family of Acid-Cleavable Linker Based on Cyclic Acetal Motifs for the Production of Antibody-Drug Conjugates with High Potency and Selectivity	15
Noninvasive Analysis of Peptidoglycan from Living Animals	15
Light-Activated Molecular Purification (LAMP) of Recombinant Proteins	15
Issue Publication Information	15
Development of a Decafluorobiphenyl Cyclized Peptide Targeting the NEMO–IKKα/β Interaction that Enhances Cell Penetration and Attenuates Lipopolysaccharide-Induced Acute Lung Injury	15
Lectin-Functionalized Chitosan Nanoparticle-Based Biosensor for Point-of-Care Detection of Bacterial Infections	15
Asymmetry of Dual-Display DNA-Encoded Chemical Libraries	15
Mechanistic Characterization of the Potency of THIOMAB Antibody–Drug Conjugates Targeting Staphylococcus aureus and ETbR-Expressing Tumor Cells Using Quantitative LC-MS/MS Analysis of Intracell	15
A Switch-On Affinity-Based Iridium(III) Conjugate Probe for Imaging Mitochondrial Glutathione S-Transferase in Breast Cancer Cells	15
Resveratrol Carbon Dots Disrupt Mitochondrial Function in Cancer Cells	15
Long-Acting Poly(ADP-ribose) Polymerase Inhibitor Prodrug for Humans	15
Effect of Click Chemistry Linkages on the Biological Behavior of Albumin-Binding ¹⁷⁷Lu-DOTAGA-pIBA-LLP2A Analogues Targeting Melanoma	15
Synthetic and Computational Design Insights toward Mimicking Protein Binding of Phosphate	14
Zinc Triggered Release of Encapsulated Cargo from Liposomes via a Synthetic Lipid Switch	14
Genetic Determinants of Surface Accessibility in Staphylococcus aureus	14
NIR-Triggered On-Demand Nitric Oxide Release for Enhanced Synergistic Phototherapy of Hypoxic Tumor	14
Complex DNA Architectonics─Self-Assembly of Amphiphilic Oligonucleotides into Ribbons, Vesicles, and Asterosomes	14
Issue Publication Information	14
Precise Manipulation of the Site and Stoichiometry of Capsid Modification Enables Optimization of Functional Adeno-Associated Virus Conjugates	14
Conceptualization and Preliminary Characterization of Poloxamer-Based Hydrogels for Biomedical Applications	14
Fluorescence-Based Simple and Practical Assay Method for DNA Damage Analysis in DNA-Encoded Library Synthesis	14
Bypassing the Need for Cell Permeabilization: Nanobody CDR3 Peptide Improves Binding on Living Bacteria	14
Lipophilic Anchors that Embed Bioconjugates in Bilayer Membranes: A Review	14
Issue Publication Information	14
Click Chemistry Enables [⁸⁹Zr]Zr-DOTA Radioimmunoconjugation for Theranostic ⁸⁹Zr-immunoPET	14
Sensitive Detection of the Human Epididymis Protein-4 (HE4) Ovarian Cancer Biomarker through a Sandwich-Type Immunoassay Method with Laser-Induced Breakdown Spectroscopy	14
Photoactivatable Liposomes for Blue to Deep Red Light-Activated Surface Drug Release: Application to Controlled Delivery of the Antitumoral Drug Melphalan	14
pH-Responsive Amphiphilic Triblock Fluoropolymers as Assemble Oxygen Nanoshuttles for Enhancing PDT against Hypoxic Tumor	14
Metal-Free Click-Chemistry: A Powerful Tool for Fabricating Hydrogels for Biomedical Applications	14
Human Behavior-Inspired Linchpin-Directed Catalysis for Traceless Precision Labeling of Lysine in Native Proteins	13
Design, Synthesis, and Anticancer Activity of Triptycene–Peptide Hybrids that Induce Paraptotic Cell Death in Cancer Cells	13
Modular Display of Plasmodium yoelii Circumsporozoite Surface Protein and Merozoite Surface Protein-1 on Norovirus-like Particles	13
Customizable Click Biochemistry Strategy for the Design and Preparation of Glucagon-like Peptide-1 Conjugates and Coagonists	13
Organotropic Targeting of Biomimetic Nanoparticles to Treat Lung Disease	13
Quantum Dot Erythropoietin Bioconjugates Enhance EPO-Receptor Clustering on Transfected Human Embryonic Kidney Cells	13
Self-Assembly of the Tetraphenylethylene-Capped Diserine through a Hierarchical Assembly Process	13
Radiation Cleaved Drug-Conjugate Linkers Enable Local Payload Release	13
A Simple and Versatile Strategy for Oriented Immobilization of His-Tagged Proteins on Magnetic Nanoparticles	13
Synergistic Experimental and Computational Investigation of the Bioorthogonal Reactivity of Substituted Aryltetrazines	13
Harnessing Fc-Directed Bioconjugation for the Synthesis of Site-Specifically Modified Radioimmunoconjugates	13
Matrix Metalloproteinase-Responsive Drug Delivery Systems	13
Developing and Characterizing the Tumor-Targeting Efficiency of an Anti-EphA2-CD11b Bispecific Antibody	13
Miniaturized Synthetic Palmitoylation Motifs for Small-Molecule Localization in Living Cells	13
Development of an Albumin–Polymer Bioconjugate via Covalent Conjugation and Supramolecular Interactions	13
Phosphorothioate-Modified DNA Aptamer-Based PROTACs for Targeted Degradation of Estrogen Receptor α	13
Crossing the Solubility Rubicon: 15-Crown-5 Facilitates the Preparation of Water-Soluble Sulfo-NHS Esters in Organic Solvents	13
RGD and Scutellarin Conjugate (WK001) Targeting Platelet Glycoprotein IIb/IIIa Receptor Protects from Myocardial Ischemia/Reperfusion Injury: Synthesis, Characterization, and Bioactivity Evaluation	13
Synthesis and Biological Evaluation of Bile Acid–Triclosan Conjugates: A Study on Antibacterial, Antibiofilm, and Molecular Docking	13
Chemistry of DNA Nanotechnology Special Issue	13
Development of a Long-Acting Myeloid-Derived Growth Factor via Site-Specific PEGylation	12
Issue Publication Information	12
Targeted NIR Fluorescent Mechanically Interlocked Molecules-Peptide Bioconjugate for Live Cancer Cells Submitochondrial Stimulated Emission Depletion Super-Resolution Microscopy	12
Mirror-Image Single-Domain Antibody for a Novel Nonimmunogenic Drug Scaffold	12
Synergism of ⁶⁴Cu-Labeled RGD with Anti-PD-L1 Immunotherapy for the Long-Acting Antitumor Effect	12
Multilayer Fluorescent Immunoassay for Early and Sensitive Dengue Virus Detection Using Host and Viral Biomarkers	12
Engineering a High-Affinity Anti-Methoxy Poly(ethylene glycol) (mPEG) Antibody for Sensitive Immunosensing of mPEGylated Therapeutics and mPEG Molecules	12
One-Step Conversion of NHS Esters to Reagents for Site-Directed Labeling of IgG Antibodies	12
Issue Publication Information	12
Photochemical-Promoted Cross-Coupling Reaction of Alkyl Boronate Esters with DNA-Conjugated Aryl Bromides for DNA-Encoded Library Synthesis	12
Fluorophore Labeling of Proteins: a Versatile Trigger–Release–Conjugation Platform Based on the Quinone Methide Chemistry	12
Dynamic Catalysis Guided by Nucleic Acid Networks and DNA Nanostructures	12
Harnessing DNA Nanotechnology and Chemistry for Applications in Photonics and Electronics	12
A Multifunctional Contrast Agent for ¹⁹F-Based Magnetic Resonance Imaging	12
Synthetic Amine Linkers for Efficient Sortagging	12
Issue Editorial Masthead	12
Bioreducible Amphiphilic Hyperbranched Polymer-Drug Conjugate for Intracellular Drug Delivery	12
Point-of-Care Testing for Norovirus Typing Using CRISPR/Cas12a Combined with Reverse Transcription Recombinase Polymerase Amplification	12

Carbon Dots as Potential Therapeutic Agents for Treating Non-Alcoholic Fatty Liver Disease and Associated Inflammatory Bone Loss	12
Dual-Boronic Acid Reagents That Combine Dynamic and Covalent Bioconjugation	12
Aptamer- vs Fab-Conjugated Liposomes: A Comparative Study in Targeting Acute Myeloid Leukemia Cells	11
Design and Optimization of an α-Helical Bundle Dimer Cell-Penetrating Peptide for In Vivo Drug Delivery	11
Rapid Production of Bispecific Antibodies from Off-the-Shelf IgGs with High Yield and Purity	11
Solid-Phase Collateral Cleavage System Based on CRISPR/Cas12 and Its Application toward Facile One-Pot Multiplex Double-Stranded DNA Detection	11
Generation of Multivalent Nanobody-Based Proteins with Improved Neutralization of Long α-Neurotoxins from Elapid Snakes	11
Correction to “Oral Delivery of Peptide Drugs Using Nanoparticles Self-Assembled by Poly(γ-glutamic acid) and a Chitosan Derivative Functionalized by Trimethylation”	11
Recent Advances in Bioorthogonal Click Chemistry for Biomedical Applications	11
Cyclopentadiene as a Multifunctional Reagent for Normal- and Inverse-Electron Demand Diels–Alder Bioconjugation	11
Developing ⁶⁸ Ga-Labeled Exendin(9–39) Derivatives for PET Imaging of Insulinomas	11
Modular PET Agent Construction Strategy through Strain-Promoted Double-Click Reagent with Efficient Photoclick Step	11
Peptide Amphiphile Hydrogels Based on Homoternary Cucurbit[8]uril Host-Guest Complexes	11
IgG-Binding Nanobody Capable of Prolonging Nanobody-Based Radiotracer Plasma Half-Life and Enhancing the Efficacy of Tumor-Targeted Radionuclide Therapy	11
Issue Publication Information	11
Tumor-Derived PD-L1⁺ Exosomes with Natural Inflammation Tropism for Psoriasis-Targeted Treatment	11
Formal [4 + 2] Cycloadditions of Maleimides on Duplex DNA	11
Synthesis of DNA-Encoded Bicyclic Peptides via Cysteine-Promoted Cyclization and Amide Condensation Reaction	11
Sustained Releasable Copper and Zinc Biogenic Ions Co-Assembled in Metal–Organic Frameworks Reinforced Bacterial Eradication and Wound Mitigation in Diabetic Mice	11
Live-Cell Mitochondrial Targeted NIR Fluorescent Covalent Labeling of Specific Proteins Using a Dual Localization Effect	11
Guest-Induced Planar-Chiral Pillar[5]arene Surface for Selectively Adsorbing Protein Based on Host–Guest Chemistry	11
Azobenzene-Based Amino Acids for the Photocontrol of Coiled-Coil Peptides	10
Issue Publication Information	10
Light-Activated Nanodiamond-Based Drug Delivery Systems for Spatiotemporal Release of Antisense Oligonucleotides	10
pH/ROS Dual-Responsive Self-Amplified ROS-Replenishing Self-Delivery Systems for Tumor-Specific Chemotherapy/Ferroptosis	10
Multivalent Cucurbituril Dendrons for Cell Membrane Engineering with Supramolecular Receptors	10
Linker and Conjugation Site Synergy in Antibody–Drug Conjugates: Impacts on Biological Activity	10
Covalent and Oriented Immobilization of Antibodies through Systematic Modification of Photoactivatable RNA Hybrid Aptamers	10
Issue Publication Information	10
Issue Editorial Masthead	10
Human CD47-Derived Cyclic Peptides Enhance Engulfment of mAb-Targeted Melanoma by Primary Macrophages	10
Impact of Drug Conjugation on Thermal and Metabolic Stabilities of Aglycosylated and N-Glycosylated Antibodies	10
iFLinkC-X: A Scalable Framework to Assemble Bespoke Genetically Encoded Co-polymeric Linkers of Variable Lengths and Amino Acid Composition	10
Stearylated Macropinocytosis-Inducing Peptides Facilitating the Cellular Uptake of Small Extracellular Vesicles	10
In Situ Visualizing Nascent RNA by Exploring DNA-Templated Oxidative Amination of 4-Thiouridine	10
New Triazacycloalkane Derivatives as Cytotoxic Agents for CLL Treatment: From Proof of Concept to the Targeting Biomolecule	10
Issue Publication Information	10
Cationic Micelles Outperform Linear Polymers for Delivery of Antisense Oligonucleotides in Serum: An Exploration of Polymer Architecture, Cationic Moieties, and Cell Addition Order	10
Issue Editorial Masthead	10
HOCl-Activated Reactive Organic Selenium Delivery Platform for Alleviation of Inflammation	10
Targeted Delivery of TLR7 Agonists to the Tumor Microenvironment Enhances Tumor Immunity via Activation of Tumor-Resident Myeloid Cells	10
Delivery of Targeted Co(III)–DNA Inhibitors of Gli Proteins to Disrupt Hedgehog Signaling	10
Cationic Peptide Conjugation Enhances Intratumoral Retention and Antitumor Efficacy of Immune Checkpoint Blockade Antibodies	10
Lipid Nanoparticles for Brain Tumor Theranostics: Challenges and Status	10
Large Protein Assemblies for High-Relaxivity Contrast Agents: The Case of Gadolinium-Labeled Asparaginase	10
Light-Controlled Promiscuous Cell Adhesion through the Plasma Membrane-Binding Protein BcLOV4	10
Chemo-Enzymatic Synthesis of Viscoelastic Pseudopeptidoglycan Networks	10
Carbonic Anhydrase IX Targeting Mn(II)-Based Magnetic Resonance Molecular Imaging Probe for Hypoxia Tumors	10
Mitigating Cannabidiol’s Non-Selective Cytotoxicity via Subcellular Organelle Targeting: Exploring Mitochondrial Targeting Potential	10
Synthesis and Evaluation of Three Azide-Modified Disaccharide Oxazolines as Enzyme Substrates for Single-Step Fc Glycan-Mediated Antibody-Drug Conjugation	10
Application of N-Terminal Site-Specific Biotin and Digoxigenin Conjugates to Clinical Anti-drug Antibody Assay Development	9
Gold Nanoclusters: Imaging, Therapy, and Theranostic Roles in Biomedical Applications	9
Issue Editorial Masthead	9
4′-C-Cholesterol/Pyridyl-2′-O-Methyl Uridine-Functionalized siRNA Enhances Stability and Carrier-Free Gene Silencing	9
Issue Editorial Masthead	9
One-Pot, One-Step Synthesis of Drug-Loaded Magnetic Multimicelle Aggregates	9
Lysosome-Specific Delivery of β-Glucosidase Enzyme Using Protein-Glycopolypeptide Conjugate via Protein Engineering and Bioconjugation	9
Construction of Self-Assembling Lipopeptide-Based Benign Nanovesicles to Prevent Amyloid Fibril Formation and Reduce Cytotoxicity of GxxxGxxxGxxxG Motif	9
Superresolution Imaging with Single-Antibody Labeling	9
Binary Copolymer Blending Enhances pDNA Delivery Performance and Colloidal Shelf Stability of Quinine-Based Polyplexes	9
Rapid Covalent Labeling of Membrane Proteins on Living Cells Using a Nanobody–Epitope Tag Pair	9
Transferrin Receptor-Targeted Aptamer–Drug Conjugate Overcomes Blood–Brain Barrier for Potent Glioblastoma Therapy	9
AUNP-12 Near-Infrared Fluorescence Probes across NIR-I to NIR-II Enable In Vivo Detection of PD-1/PD-L1 Axis in the Tumor Microenvironment	9
Intravenous Hemostats: Foundation, Targeting, and Controlled-Release	9
Dynamics of DNA Origami Lattices	9
Recent Progress in Hydrogen Sulfide-Generating Nanomedicines for Cancer Therapy: From Design to In Situ Generation	9
Diligent Design Enables Antibody-ASO Conjugates with Optimal Pharmacokinetic Properties	9
Issue Publication Information	9
H₃TPAN-Triazole-Bn-NH₂: Tripicolinate Clicked-Bifunctional Chelate for [²²⁵Ac]/[¹¹¹In] Theranostics	9
Synthesis of 5′-Thiol Functionalized Morpholino Oligo-Nucleotide and Subsequent Conjugation with IGT to Improve Delivery and Antisense Efficacy In Vitro	9
Issue Publication Information	9
Issue Editorial Masthead	9
Thymidine Phosphodiester Chemiluminescent Probe for Sensitive and Selective Detection of Ectonucleotide Pyrophosphatase 1	9
Development of a Mesothelin-Binding Engineered Scaffold Protein as a Theranostic for Pleural Mesothelioma	9
Evolution of Lipo-Xenopeptide Carriers for siRNA Delivery: Interplay of Stabilizing Subunits	9
Engineering the Propeptide of Microbial Transglutaminase Zymogen: Enabling Substrate-Dependent Activation for Bioconjugation Applications	9
Antibody-Free Immunopeptide Nanoconjugates for Brain-Targeted Drug Delivery in Glioblastoma Multiforme	9
RPA-CRISPR-Cas-Mediated Dual Lateral Flow Assay for the Point-of-Care Testing of HPV16 and HPV18	8
Surface Presentation of Hyaluronic Acid Modulates Nanoparticle–Cell Association	8
In Vivo Comparative Study of Radioiodinated Folate Receptor Targeting Albumin Probes for Atherosclerosis Plaque Imaging	8
Dendrimer-Based Nanogels for Cancer Nanomedicine Applications	8
Quantitative Analysis of Extracellular Vesicle Uptake and Fusion with Recipient Cells	8
Elucidating the Impact of Payload Conjugation on the Cell-Penetrating Efficiency of the Endosomal Escape Peptide dfTAT: Implications for Future Designs for CPP-Based Delivery Systems	8
Advancing the Utility of DNA Origami Technique through Enhanced Stability of DNA-Origami-Based Assemblies	8
Issue Editorial Masthead	8
Issue Publication Information	8
Doxorubicin-Loaded Walnut-Shaped Polydopamine Nanomotor for Photothermal-Chemotherapy of Cancer	8
Improving the Encapsulation Efficiency of Lipase in Molecular Cages and Its Application	8
Mitochondria-Targeting Antimicrobial Peptide (AMP) Regulating N6-Methyladenosine (m6A) Modification to Promote Colon Cancer Ferroptosis	8
Applications of Synthetic Receptors in Bioanalysis and Drug Transport	8
Biomaterial-Mediated Exogenous Facile Coating of Natural Killer Cells for Enhancing Anticancer Efficacy toward Hepatocellular Carcinoma	8
Improvement of the Nuclease Resistance and Immunostimulatory Activity of CpG Oligodeoxynucleotides by Conjugation to Sugar-Immobilized Gold Nanoparticles	8
Gastrodin Liposomes Block Crosstalk between Astrocytes and Glioma Cells via Downregulating Cx43 to Improve Antiglioblastoma Efficacy of Temozolomide	8
Site-Specific Conjugation of Native Antibody: Transglutaminase-Mediated Modification of a Conserved Glutamine While Maintaining the Primary Sequence and Core Fc Glycan via Trimming with an Endoglycosi	8
From Bench to Cell: A Roadmap for Assessing the Bioorthogonal “Click” Reactivity of Magnetic Nanoparticles for Cell Surface Engineering	8