OOIR: Observatory of International Research

Papers

(The TQCC of Bioconjugate Chemistry is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Issue Publication Information	227
Cyclohexanediamine Triazole (CHDT) Functionalization Enables Labeling of Target Molecules with Al¹⁸F/⁶⁸Ga/¹¹¹In	158
Chemoselective Reagents for the Traceless Bioreversible Modification of Native Proteins	111
Bioorthogonal PEGylation Prolongs the Elimination Half-Life of N-TIMP2 While Retaining MMP Inhibition	97
Advances in Optical Sensors of N-Acetyl-β-d-hexosaminidase (N-Acetyl-β-d-glucosaminidase)	84
Therapeutic Potential of MF-TTZ-MMAE, a Site-Specifically Conjugated Antibody-Drug Conjugate, for the Treatment of HER2-Overexpressing Breast Cancer	64
Formal [4 + 2] Cycloadditions of Maleimides on Duplex DNA	55
Issue Editorial Masthead	53
Issue Editorial Masthead	50
Issue Editorial Masthead	49
Issue Publication Information	43
Issue Publication Information	42
Issue Editorial Masthead	40
Issue Editorial Masthead	39
Facile Synthesis of a Redox-Responsive Hyperbranched Polymer Prodrug as a Unimolecular Micelle for the Tumor-Selective Drug Delivery	37
PEGylation of anti-MerTK Antibody Modulates Ocular Biodistribution	36
Correction to “Direct Loading and Tunable Release of Antibiotics from Polyelectrolyte Multilayers To Reduce Bacterial Adhesion and Biofilm Formation”	35
Issue Editorial Masthead	35
Issue Publication Information	35
Issue Publication Information	34
Issue Publication Information	33
Issue Publication Information	32
Issue Publication Information	31
Functionalization of Biomimetic Polydopamine Shells Constructed onto Bismuth-Core Particles for pH-Mediated Drug Targeting to Heal Bacterial Infections	30
Evaluation of Cellular Targeting by Fab′ vs Full-Length Antibodies in Antibody–Nanoparticle Conjugates (ANCs) Using CD4 T-cells	29

Targeted Delivery of TLR7 Agonists to the Tumor Microenvironment Enhances Tumor Immunity via Activation of Tumor-Resident Myeloid Cells	29
Issue Editorial Masthead	28
Synthesis of First Coumarin Fluorescent Dye for Actin Visualization	28
Palladium-Mediated S-Arylation of Cysteine Residues with 4-[¹⁸F]Fluoroiodobenzene ([¹⁸F]FIB)	27
Issue Publication Information	27
Correction to “3D Printed Multifunctional Ti₆Al₄V-Based Hybrid Scaffold for the Management of Osteosarcoma”	26
Toolbox of Clickable Benzylguanines for Labeling of HoxB8-Derived Macrophages via SNAP-Tag and Bioorthogonal Chemistry	26
Issue Publication Information	25
The Effect of the Size of Gold Nanoparticle Contrast Agents on CT Imaging of the Gastrointestinal Tract and Inflammatory Bowel Disease	25
Delivery of Tempol from Polyurethane Nanocapsules to Address Oxidative Stress Post-Injury	25
Impact of Drug Conjugation on Thermal and Metabolic Stabilities of Aglycosylated and N-Glycosylated Antibodies	24
Chemical Synthesis and Poly(ethylene glycol)-Like Conjugation of the Mango-II Fluorogenic RNA Aptamer	24
Targeted Polymersomes Enable Enhanced Delivery to Peripheral Nerves Post-Injury	24
Issue Editorial Masthead	23
Live-Cell Mitochondrial Targeted NIR Fluorescent Covalent Labeling of Specific Proteins Using a Dual Localization Effect	23
Issue Publication Information	23
Bioconjugate Biomaterials: Leveraging Biology for the Next Generation of Active Materials	23
Modular Click Assembly DNA-Encoded Glycoconjugate Libraries with on-DNA Functional Group Transformations	23
Issue Publication Information	23
Non-Genetic Generation of Antibody Conjugates Based on Chemoenzymatic Tyrosine Click Chemistry	23
Near-Infrared Photoresponsive Nanotransducers for Precise Regulation of Gene Expression	23
S9.6 Antibody–Enzyme Conjugates for the Detection of DNA–RNA Hybrids	22
Dimeric Metal-Salphen Complexes Which Target Multimeric G-Quadruplex DNA	22
Break to Build: Isothermal Assembly of Nucleic Acid Nanoparticles (NANPs) via Enzymatic Degradation	22
Tumor-Derived PD-L1⁺ Exosomes with Natural Inflammation Tropism for Psoriasis-Targeted Treatment	22
A Functionalizable Analog of the Yariv Reagent for AGP Imaging using Fluorescence Microscopy	21
Enolate–Azide [3 + 2]-Cycloaddition Reaction Suitable for DNA-Encoded Library Synthesis	21
Site-Specific Chemical Modification of a Cytokine Mimic for Small Molecule-Based Tumor Targeting	21
CD22L Conjugation to Insulin Attenuates Insulin-Specific B Cell Activation	20
Correction to Development of an Effective Functional Lipid Anchor for Membranes (FLAME) for the Bioorthogonal Modification of the Lipid Bilayer of Mesenchymal Stromal Cells	20
Synthesis of Isolated DNA Aptamer and Its Application of AC-Electrothermal Flow-Based Rapid Biosensor for the Detection of Dengue Virus in a Spiked Sample	20
A Dual-Mechanism Targeted Bioorthogonal Prodrug Therapy	20
Site-Specific ⁶⁸Ga Radiolabeling of Trastuzumab Fab via Methionine for ImmunoPET Imaging	20
Hollow Cobalt Sulfide Nanospheres with Highly Enzyme-like Antibacterial Activities to Accelerate Infected Wound Healing	20
Characterization of an N-Allylglyoxylamide-Based Bioorthogonal Nitrone Trap	20
A Cysteine-Maleimide-Based Design for Hemostatic, Antibacterial, and Biodegradable Wound Dressing	19
Polysaccharide-Based Coacervate Microgel Bearing Cationic Peptides That Achieve Dynamic Cell-Membrane Structure Alteration and Facile Cytosolic Infusion of IgGs	19
Chemical Synthesis of Interleukin-6 for Mirror-Image Screening	19
Efficient Chemical Synthesis of Multi-Monoubiquitylated and Diubiquitylated Histones by the α-Halogen Ketone-Mediated Strategy	19
Solid-Phase Synthesis of Caged Luminescent Peptides via Side Chain Anchoring	19
Identification of a Novel Transasparaginase Activity of Bacillus subtilis (bTG) for Sequence-Specific Bioconjugation	19
Linker Chemistry and Connectivity Fine-Tune the Immune Response and Kinetic Solubility of Conjugated NOD2/TLR7 Agonists	19
Site-Specific Modification of Single Domain Antibodies by Enzyme-Immobilized Magnetic Beads	19
Transthyretin-Penetratin: A Potent Fusion Protein Inhibitor against Alzheimer’s Amyloid-β Fibrillogenesis with High Blood Brain Barrier Crossing Capability	19
Duo-Chol: A Photoconvertible Live Cell Imaging Tool for Tracking Cholesterol	19
Suppressing Pancreatic Cancer Survival and Immune Escape via Nanoparticle-Modulated STING/STAT3 Axis Regulation	19
Pathologic Tissue Injury and Inflammation in Mice Immunized with Plasmid DNA-Encapsulated DOTAP-Based Lipid Nanoparticles	18
Molecular Switch Engineering for Precise Genome Editing	18
Gallic Acid-Encapsulated PAMAM Dendrimers as an Antioxidant Delivery System for Controlled Release and Reduced Cytotoxicity against ARPE-19 Cells	18
Equimolar Cross-Coupling Using Reactive Coiled Coils for Covalent Protein Assemblies	18

Design and Synthesis of Piperazine-Based Compounds Conjugated to Humanized Ferritin as Delivery System of siRNA in Cancer Cells	18
Drug Delivery Targeting Neuroinflammation to Treat Brain Diseases	18
Hypoxia-Activated Prodrug Enabling Synchronous Chemotherapy and HIF-1α Downregulation for Tumor Treatment	18
Tritium O-Methylation of N-Alkoxy Maleimide Derivatives as Labeling Reagents for Biomolecules	17
One-Pot Conversion of Free Sialoglycans to Functionalized Glycan Oxazolines and Efficient Synthesis of Homogeneous Antibody–Drug Conjugates through Site-Specific Chemoenzymatic Glycan Remodeling	17
Bioresorbable Depot for Sustained Release of Immunostimulatory Resiquimod in Suppressing Both Primary Triple-Negative Breast Tumors and Metastatic Occurrence	17
Positron Emission Tomography Tracer Design of Targeted Synthetic Peptides via ¹⁸F-Sydnone Alkyne Cycloaddition	17
Highly Photoluminescent Nitrogen- and Zinc-Doped Carbon Dots for Efficient Delivery of CRISPR/Cas9 and mRNA	17
Monitoring Human Neutrophil Activation by a Proteinase 3 Near-Infrared Fluorescence Substrate-Based Probe	17
Synthetic Pept-Ins as a Generic Amyloid-Like Aggregation-Based Platform for In Vivo PET Imaging of Intracellular Targets	16
Targeted Anti-Cancer Provascular Therapy Using Ultrasound, Microbubbles, and Nitrite to Increase Radiotherapy Efficacy	16
Peptide Amphiphile Hydrogels Based on Homoternary Cucurbit[8]uril Host-Guest Complexes	16
Optimization of Enzymolysis Clearance Strategy To Enhance Renal Clearance of Radioligands	16
Hydrolytically Stable Maleimide-End-Functionalized Polymers for Site-Specific Protein Conjugation	16
Gene Regulation Using Nanodiscs Modified with HIF-1-α Antisense Oligonucleotides	16
Ligand-Modulated Catalytic Selectivity of Ag Clusterzyme for Relieving Multiorgan Injury via Inhabiting Acute Oxidative Stress	16
New Phenol Esters for Efficient pH-Controlled Amine Acylation of Peptides, Proteins, and Sepharose Beads in Aqueous Media	16
Guest-Induced Planar-Chiral Pillar[5]arene Surface for Selectively Adsorbing Protein Based on Host–Guest Chemistry	16
RGD-Modified Titanium as an Improved Osteoinductive Biomaterial for Use in Dental and Orthopedic Implants	16
Sculpting a Uniquely Reactive Cysteine Residue for Site-Specific Antibody Conjugation	15
Albumin Biomolecular Drug Designs Stabilized through Improved Thiol Conjugation and a Modular Locked Nucleic Acid Functionalized Assembly	15
Rapid Production of Bispecific Antibodies from Off-the-Shelf IgGs with High Yield and Purity	15
Cyanine Masking: A Strategy to Test Functional Group Effects on Antibody Conjugate Targeting	15
Exo-Enzymatic Addition of Diazirine-Modified Sialic Acid to Cell Surfaces Enables Photocrosslinking of Glycoproteins	15
Clickable Albumin Nanoparticles for Pretargeted Drug Delivery toward PD-L1 Overexpressing Tumors in Combination Immunotherapy	15
A Series of Furimazine Derivatives for Sustained Live-Cell Bioluminescence Imaging and Application to the Monitoring of Myogenesis at the Single-Cell Level	15
Designing Functional Bionanoconstructs for Effective In Vivo Targeting	15
6-Iodopurine as a Versatile Building Block for RNA Purine Architecture Modifications	15
Xylose Dehydrogenase Immobilized on Ferromagnetic Nanoparticles for Bioconversion of Xylose to Xylonic Acid	15
Natural and Synthetic Sortase A Substrates Are Processed by Staphylococcus aureus via Different Pathways	15
“On-Demand” Antimicrobial Photodynamic Activity through Supramolecular Photosensitizers Built with Rose Bengal and (p-Vinylbenzyl)triethylammomium Polycation Derivatives	15
Correction to “Oral Delivery of Peptide Drugs Using Nanoparticles Self-Assembled by Poly(γ-glutamic acid) and a Chitosan Derivative Functionalized by Trimethylation”	14
Synthesis and Evaluation of Three Azide-Modified Disaccharide Oxazolines as Enzyme Substrates for Single-Step Fc Glycan-Mediated Antibody-Drug Conjugation	14
Click Chemistry Enables Rapid Amplification of Full-Length Reverse Transcripts for Long-Read Third Generation Sequencing	14
Engineering and Validation of a Peptide-Stabilized Poly(lactic-co-glycolic) Acid Nanoparticle for Targeted Delivery of a Vascular Disruptive Agent in Cancer Therapy	14
Modular Adapters Utilizing Binders of Different Molecular Types Expand Cell-Targeting Options for Adenovirus Gene Delivery	14
Camouflaged Fluorescent Silica Nanoparticles Target Aggregates and Condensates of the Amyloidogenic Protein Tau	14
Correction to “Multifunctional Nanoflowers for Simultaneous Multimodal Imaging and High-Sensitivity Chemo-Photothermal Treatment”	14
Tyrosinase-Related Protein2 Peptide with Replacement of N-Terminus Residue by Cysteine Binds to H-2K^b and Induces Antigen-Specific Cytotoxic T Lymphocytes after Conjugation with CpG-DNA	14
Design and Optimization of an α-Helical Bundle Dimer Cell-Penetrating Peptide for In Vivo Drug Delivery	14
DNA Origami–Platelet Adducts: Nanoconstruct Binding without Platelet Activation	14
Structure-Dependent Nontraditional Intrinsic Fluorescence of Aliphatic Hyperbranched Polyureas	14
Modular PET Agent Construction Strategy through Strain-Promoted Double-Click Reagent with Efficient Photoclick Step	14
Development of a Micellar-Promoted Heck Reaction for the Synthesis of DNA-Encoded Libraries	14
Sonotheranostics and Sonogenetics Special Issue	13
Insight into the Covalently Oriented Immobilization of Antibodies on Gold Nanoparticle Probes to Improve Sensitivity in the Colorimetric Detection of Listeria monocytogenes	13
Strategies to Control or Mimic Growth Factor Activity for Bone, Cartilage, and Osteochondral Tissue Engineering	13
Preparation of Maleimide-Modified Oligonucleotides from the Corresponding Amines Using N-Methoxycarbonylmaleimide	13
Easy Surface Functionalization and Bioconjugation of Peptides as Capture Agents of a Microfluidic Biosensing Platform for Multiplex Assay in Serum	13
Supramolecular Bioconjugation Strategy for Antibody-Targeted Delivery of siRNA	13
Issue Editorial Masthead	13
Rational Approach to Improve Detergent Efficacy for Membrane Protein Stabilization	13
Efficiency and Safety of Dextran-PAMAM/siMMP-9 Complexes for Decreasing Matrix Metalloproteinase-9 Expression and Promoting Wound Healing in Diabetic Rats	13
Design, Mechanical Properties, and Dynamics of Synthetic DNA Filaments	13
Copper-Containing Artificial Polyenzymes as a Clickase for Bioorthogonal Chemistry	13
3D Printed Multifunctional Ti₆Al₄V-Based Hybrid Scaffold for the Management of Osteosarcoma	13
Metal Polyphenol Nanoparticle-Based Chemo/Ferroptosis Synergistic Therapy for the Treatment of Oral Squamous Cell Carcinoma	13
Azobenzene-Based Amino Acids for the Photocontrol of Coiled-Coil Peptides	13
Incorporation of Intracellular NanoSIMS Tracers to Oligonucleotide Conjugates via Strain Promoted Sydnone–Alkyne Cycloaddition	13
Antibody-Mediated Screening of Peptide Inhibitors for Monoamine Oxidase-B (MAO-B) from an Autodisplayed F_V Library	13
Stimuli-Responsive Regulation of Biocatalysis through Metallic Nanoparticle Interaction	13
Development of a Versatile Cancer Vaccine Format Targeting Antigen-Presenting Cells Using Proximity-Based Sortase A-Mediated Ligation of T-Cell Epitopes	13
Bioderived Lipoic Acid-Based Dynamic Covalent Nanonetworks of Poly(disulfide)s: Enhanced Encapsulation Stability and Cancer Cell-Selective Delivery of Drugs	13
Bioorthogonal Chemical Engineering of rAAV Capsid: Advancing Gene Therapy Targeting Using Proteins	13
Environment-Sensitive Nucleoside Probe Unravels the Complex Structural Dynamics of i-Motif DNAs	12
Bioorthogonal Chemistry and Its Applications	12
Aptamer- vs Fab-Conjugated Liposomes: A Comparative Study in Targeting Acute Myeloid Leukemia Cells	12
Cysteine-Based Coupling: Challenges and Solutions	12
Synthesis and Evaluation of Ubiquitin–Dioxetane Conjugate as a Chemiluminescent Probe for Monitoring Deubiquitinase Activity	12
Receptor-Mediated Transmembrane Activation of Protein Folding in Synthetic Cells	12
Cationic Micelles Outperform Linear Polymers for Delivery of Antisense Oligonucleotides in Serum: An Exploration of Polymer Architecture, Cationic Moieties, and Cell Addition Order	12
Biomedical Application of Porphyrin-Based Amphiphiles and Their Self-Assembled Nanomaterials	12
Cyclopentadiene as a Multifunctional Reagent for Normal- and Inverse-Electron Demand Diels–Alder Bioconjugation	12
A β-Cyclodextrin-Albumin Conjugate for Enhancing Therapeutic Efficacy of Cytotoxic Drugs	12
Synthesis and Characterization of a Positron Emission Tomography Imaging Probe Selectively Targeting the Second Bromodomain of Bromodomain Protein BRD4	12
Issue Editorial Masthead	12
Biocatalytic Clusterzyme Patches Restore Lung Function via Immunomodulation and Mitochondria Protection	12
Affinity-Based Kinase-Catalyzed Crosslinking to Study Kinase–Substrate Pairs	12
3D-Printing Biodegradable PU/PAAM/Gel Hydrogel Scaffold with High Flexibility and Self-Adaptibility to Irregular Defects for Nonload-Bearing Bone Regeneration	12
Recent Advances in Bioorthogonal Click Chemistry for Enhanced PET and SPECT Radiochemistry	12

Development of Radiopharmaceuticals for NPY Receptor-5 (Y5) Nuclear Imaging in Tumors by Synthesis of Specific Agonists and Investigation of Their Binding Mode	12
Blended Block Polycation Micelles Enhance Antisense Oligonucleotide Delivery	12
Rational Design of Site-Specific Fatty Acid Derivatives to Extend the Half-Life of Fibroblast Growth Factor 21	12
Linker Architectures as Steric Auxiliaries for Altering Enzyme-Mediated Payload Release from Bioconjugates	12
Penetrating the Blood-Brain Barrier with New Peptide–Porphyrin Conjugates Having anti-HIV Activity	12
Issue Publication Information	11
Cathepsin B Processing Is Required for the In Vivo Efficacy of Albumin–Drug Conjugates	11
Chemoselective Bioconjugation of Amyloidogenic Protein Antigens to PEGylated Microspheres Enables Detection of α-Synuclein Autoantibodies in Human Plasma	11
Issue Editorial Masthead	11
Issue Editorial Masthead	11
Issue Editorial Masthead	11
Issue Editorial Masthead	11
A Chemoinformatic-Guided Synthesis of a Spleen-Expressing mRNA Lipid Nanoparticle Platform	11
Issue Publication Information	11
Issue Editorial Masthead	11
Issue Publication Information	11
Passivating the Background of Living Microbes with a Zwitterionic Peptide for Therapies	11
Pentafulvene–Maleimide Cycloaddition for Bioorthogonal Ligation	11
Correction to “Lactose-Modified Chitosan Gold(III)-PEGylated Complex-Bioconjugates: From Synthesis to Interaction with Targeted Galectin-1 Protein”	11
Issue Editorial Masthead	11
Issue Editorial Masthead	11
Focused Cluster: Synthetic Host–Guest Chemistry in Biology	11
2′-Modified Thymidines with Bioorthogonal Cyclopropene or Sydnone as Building Blocks for Copper-Free Postsynthetic Functionalization of Chemically Synthesized Oligonucleotides	11
Dual-Function Antibody Conjugate-Enabled Photoimmunotherapy Complements Fluorescence and Photoacoustic Imaging of Head and Neck Cancer Spheroids	10
Precision Modification of Native Antibodies	10
Issue Publication Information	10
Issue Publication Information	10
Issue Publication Information	10
Issue Editorial Masthead	10
Modulating Lysosomal pH through Innovative Multimerized Succinic Acid-Based Nucleolipid Derivatives	10
E. coli as a Smart Thermo-Vector for Combating Solid Tumors: A Synergistic Heat-Induced Cancer Therapy Approach	10
Photooxidation Responsive Elastin-Like Polypeptide Conjugates for Photodynamic Therapy Application	10
Hafnium-Doped Prussian Blue Nanoparticles with Homologous Tumor Targeting and Magnetic Resonance Imaging Ability for Enhanced Tumor Radiotherapy via Photothermal Therapy and Hypoxia Relief	10
Issue Editorial Masthead	10
Issue Editorial Masthead	10
Scalable One-Pot Production of Geranylgeranylated Proteins in Engineered Prokaryotes	10
Targeting Strategies for Site-Specific mRNA Delivery	10
Bioorthogonal Chemistry: Enzyme Immune and Protein Capture for Enhanced LC-MS Bioanalysis	10
Effect of Lipidation on the Structure, Oligomerization, and Aggregation of Glucagon-like Peptide 1	10
T Cell-Targeting Nanotherapies for Atherosclerosis	10
Design and Biological Evaluation of the Long-Acting C5-Inhibited Ornithodoros moubata Complement Inhibitor (OmCI) Modified with Fatty Acid	10
Lipid Nanoparticles for Brain Tumor Theranostics: Challenges and Status	10
Structure–Activity Relationship of Fluorinated Sialic Acid Inhibitors for Bacterial Sialylation	10
Evaluation of PSMA-Targeted TREN-CAM Conjugates for Targeted Imaging of Cancer with ⁶⁸Ga(III) and ⁴⁵Ti(IV)	10
First Comparison Study of the In Vitro and In Vivo Properties of a Randomly and Site-Specifically Conjugated SPECT/NIRF Monomolecular Multimodal Imaging Probe (MOMIP) Based on an aza-BOD	9
Generation and Biological Evaluation of Fc Antigen Binding Fragment-Drug Conjugates as a Novel Antibody-Based Format for Targeted Drug Delivery	9
Click Chemistry-Enabled Conjugation Strategy for Producing Dibenzodiazepinone-Type Fluorescent Probes To Target M₂Acetylcholine Receptors	9
Dual Blood–Brain Barrier–Glioma Targeting Peptide–Poly(levodopamine) Hybrid Nanoplatforms as Potential Near Infrared Phototheranostic Agents in Glioblastoma	9
Development of [¹⁸F]AmBF₃ Tetrazine for Radiolabeling of Peptides: Preclinical Evaluation and PET Imaging of [¹⁸F]AmBF₃-PEG₇-Tyr³-Octr	9
Supramolecular Assembly of Single-Tail ssDNA-Amphiphiles through π–π Interactions	9
Multivalent Cucurbituril Dendrons for Cell Membrane Engineering with Supramolecular Receptors	9
Acoustically Detonated Microbubbles Coupled with Low Frequency Insonation: Multiparameter Evaluation of Low Energy Mechanical Ablation	9
In Situ Visualizing Nascent RNA by Exploring DNA-Templated Oxidative Amination of 4-Thiouridine	9
Site-Specific Molecular Engineering of Nanobody–Glucoside Conjugates for Enhanced Brain Tumor Targeting	9
Evaluation of Efficient Non-reducing Enzymatic and Chemical Ligation Strategies for Complex Disulfide-Rich Peptides	9
Light-Activated Nanodiamond-Based Drug Delivery Systems for Spatiotemporal Release of Antisense Oligonucleotides	9
Issue Editorial Masthead	9
Self-Immolative Carbamate Linkers for CD19-Budesonide Antibody–Drug Conjugates	9
SARS-CoV-2 Peptide Bioconjugates Designed for Antibody Diagnostics	9
Effect of PEGylation on Host Defense Peptide Complexation with Bacterial Lipopolysaccharide	9
New Triazacycloalkane Derivatives as Cytotoxic Agents for CLL Treatment: From Proof of Concept to the Targeting Biomolecule	9
Targeted Delivery of Cabazitaxel Using Cyclic Cell-Penetrating Peptide and Biomarkers of Extracellular Matrix for Prostate and Breast Cancer Therapy	9
Human CD47-Derived Cyclic Peptides Enhance Engulfment of mAb-Targeted Melanoma by Primary Macrophages	9
Exo-Enzymatic Cell-Surface Glycan Labeling for Capturing Glycan–Protein Interactions through Photo-Cross-Linking	9
Design and Synthesis of Cathepsin-K-Activated Osteoadsorptive Fluorogenic Sentinel (OFS) Probes for Detecting Early Osteoclastic Bone Resorption in a Multiple Myeloma Mouse Model	9
Rational Design of a Dual-Targeting Natural Toxin-Like Bicyclic Peptide for Selective Bioenergetic Blockage in Cancer Cells	9
Nanoscale Effects in the Room-Temperature UV–Visible Photoluminescence from Silica Particles and Its Cancer Cell Imaging	9
Stearylated Macropinocytosis-Inducing Peptides Facilitating the Cellular Uptake of Small Extracellular Vesicles	9
Pretargeted PET Imaging with a TCO-Conjugated Anti-CD44v6 Chimeric mAb U36 and [⁸⁹Zr]Zr-DFO-PEG₅-Tz	9
Optimizing an Antioxidant TEMPO Copolymer for Reactive Oxygen Species Scavenging and Anti-Inflammatory Effects in Vivo	9
Development of Prodrug–Payloads for Targeted Therapeutic Applications of Platinum–Acridine Anticancer Agents	9
Squaramide Formation for DNA-Encoded Library Synthesis	9
A General Set of DNA-Compatible Reactions for Preparing DNA-Tagged Multisubstituted Pyrroles	9
iFLinkC-X: A Scalable Framework to Assemble Bespoke Genetically Encoded Co-polymeric Linkers of Variable Lengths and Amino Acid Composition	9
Discovery of Imaging and Therapeutic Integration Bifunctional Molecules Based on Bio-Orthogonal Reaction and Releasable Disulfide Bond	9
Artificial Nanocage Formed via Self-Assembly of β-Annulus Peptide for Delivering Biofunctional Proteins into Cell Interiors	9
Site-Specific, Platform-Based Conjugation Strategy for the Synthesis of Dual-Labeled Immunoconjugates for Bimodal PET/NIRF Imaging of HER2-Positive Tumors	9
Generation of DAR1 Antibody-Drug Conjugates for Ultrapotent Payloads Using Tailored GlycoConnect Technology	9
Photo-Controllable Phase Transition of Arylazopyrazole-Conjugated Oligonucleotides	9
Issue Editorial Masthead	9
Revival of Bioengineered Proteins as Carriers for Nucleic Acids	9
Carbonic Anhydrase IX Targeting Mn(II)-Based Magnetic Resonance Molecular Imaging Probe for Hypoxia Tumors	8
Enzymatic Spin-Labeling of Protein N- and C-Termini for Electron Paramagnetic Resonance Spectroscopy	8
Real-Time Monitoring of CAR-T Cell Efficiency through a Biorthogonal Cycloaddition Labeling Strategy	8
Scale up of Transmembrane NADH Oxidation in Synthetic Giant Vesicles	8
Assessment of the Efficacy of the Combination of RNAi of lncRNA DANCR with Chemotherapy to Treat Triple Negative Breast Cancer Using Magnetic Resonance Molecular Imaging	8
Multisite Labeling of Proteins Using the Ligand-Directed Reactivity of Triggerable Michael Acceptors	8
Luciferase NLuc Site-Specific Conjugation to Generate Reporters for In Vitro Assays	8
Luminescent Ruthenium(II) Complexes Used for the Detection of 8-Oxoguanine in the Human Telomeric Sequence	8
Directly Quantifiable Biotinylation Using a Water-Soluble Isatoic Anhydride Platform	8
Formulation and Preclinical Testing of Tc-99m-Labeled HYNIC-Glc-FAPT as a FAP-Targeting Tumor Radiotracer	8
Formation of Direction-Controllable Pseudorotaxane and Catenane Using Chemically Cyclized Oligodeoxynucleotides and Their Noncovalent RNA Labeling	8
Design, Heterologous Expression, and Application of an Immobilized Protein Kinase	8
Site-Specific Conjugation Strategy for Dual Antibody–Drug Conjugates Using Aerobic Formylglycine-Generating Enzymes	8
DNA Modifications Enabling Proximity Biotinylation	8