OOIR: Observatory of International Research

Papers

(The TQCC of Trends in Endocrinology and Metabolism is 16. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)

Article	Citations
Methionine restriction and mimetics to ameliorate human aging and disease	479
Contribution of metabolism-independent glucose sensing to metabolic homeostasis	390
Advisory Board and Contents	322
Advisory Board and Contents	245
Irisin limits amyloid-β buildup in Alzheimer’s disease	182
How does mitochondrial import machinery fine-tune mitophagy? Different paths and one destination	182
Muscle regeneration: myofibers and fat jostle for position	159
Subscription and Copyright Information	134
Advisory Board and Contents	123
The changing clinical spectrum of endocrine adverse events in cancer immunotherapy	113
Establishing evidence for immune surveillance of β-cell senescence	110
Cellular mechanism of diabetes remission by bariatric surgery	98
Unveiling the cancer risk nexus of the steatotic liver	95
N6-methyladenosine RNA modification in nonalcoholic fatty liver disease	94
Maternal metabolism influences neural tube closure	91
Cannabinoids and terpenes for diabetes mellitus and its complications: from mechanisms to new therapies	90
Mechanisms of kidney fibrosis and routes towards therapy	86
Neuroendocrine gut–brain signaling in obesity	86
Healthy choices, healthy futures: promoting healthy nutrition to curb non-communicable diseases	85
Uridine	81
Subscription and Copyright Information	78
Advisory Board and Contents	77
Advisory Board and Contents	76
Dietary medium-chain triacylglycerols in metabolic regulation	76
Increased hepatic gluconeogenesis and type 2 diabetes mellitus	75

A matter of time: temporal structure and functional relevance of macrophage metabolic rewiring	72
Why cells need iron: a compendium of iron utilisation	70
Enhancer binding as a KEysTONE of fasting response	68
A double-edged sword: risks and benefits of heat for human health	67
Subscription and Copyright Information	65
The landscape of fetus metabolism in maternal hyperglycemia	57
Advisory Board and Contents	54
‘Rotor free-wheeling’ in impaired F1FO-ATPase induces congenital hypermetabolism	53
Subscription and Copyright Information	53
Subscription and Copyright Information	53
GLP-1 agonists: superior for mind and body in antipsychotic-treated patients?	51
Beta-hydroxybutyrate	51
Subscription and Copyright Information	49
Advisory Board and Contents	48
Mechanomedicine targeting brown adipose tissue for metabolic health	47
Effects of APOE4 on omega-3 brain metabolism across the lifespan	46
Is high-intensity interval training harmful to health?	46
Parathyroid hormone–PTH1R signaling in cardiovascular disease and homeostasis	46
CD8+ T cell stressors converge on shared metabolic–epigenetic networks	44
A multidimensional epidemiological perspective on frailty dynamics and prevention	44
Current status and future perspectives of FGF21 analogues in clinical trials	44
Olfactory system and energy metabolism: a two-way street	43
Metabolic remodeling in cancer and senescence and its therapeutic implications	43
Liver-expressed antimicrobial peptide 2 (LEAP2)	42
A metabolic perspective on cuproptosis	40
Sepsis: a failing starvation response	39
Metabolism, homeostasis, and aging	39
Drosophila as a diet discovery tool for treating amino acid disorders	39
Advisory Board and Contents	38
Metabolic challengers selecting tumor-persistent cells	38
Hallmarks of the metabolic secretome	37
Can kisspeptin be a new treatment for sexual dysfunction?	36
Balancing metabolism and regeneration in liver diseases through HNF4α targeting	34
Exercise pills for cardiometabolic health cannot mimic the exercise milieu	34
Lipid-associated macrophages between aggravation and alleviation of metabolic diseases	34
New tools for bone health assessment in secreting pituitary adenomas	34
Amino acid transporters as modulators of glucose homeostasis	34
Targeting cholesterol-dependent adrenal steroidogenesis for management of primary aldosteronism	33
Pregnancy-induced metabolic reprogramming and regenerative responses to pro-aging stresses	32
Per- and polyfluoroalkyl substances as persistent pollutants with metabolic and endocrine-disrupting impacts	32
Gut microbiota and eating behaviour in circadian syndrome	32
Mitochondrial copper in human genetic disorders	32
Serine signaling governs metabolic homeostasis and health	32
The interplay between endometriosis and obesity	32
Advisory Board and Contents	32
Hypothalamic mechanisms of obesity-associated disturbance of hypothalamic–pituitary–ovarian axis	32
Exercised breastmilk: a kick-start to prevent childhood obesity?	31
Advisory Board and Contents	31
Shared metabolic and stress pathways to neonatal adiposity	31
Shifting metabolism to increase lifespan	31

B vitamins as adjunct therapies for depressive disorder	30
Single-cell imaging of liver metabolic dynamics using fluorescent biosensors	29
Rewiring of the glymphatic landscape in metabolic disorders	29
The physiological functions of lymphangiocrine signals	28
Blood-based bioenergetics: a liquid biopsy of mitochondrial dysfunction in disease	28
More trials for the unhappy hypothyroid patient on thyroxine: a clinician’s perspective	28
A three-layer perspective on miRNA regulation in β cell inflammation	28
Mitochondria as sensors of intracellular pathogens	27
Metabolic-immune microenvironment crosstalk mediating ICI resistance in MASH-HCC	27
Advisory Board and Contents	27
Cardioprotective benefits of metabolic surgery and GLP-1 receptor agonist–based therapies	27
(Poly)phenols as bioactive constituents linked to dietary fibre metabolic fate	27
Insights from omics research on plant-based diets and cardiometabolic health	26
An epidemiological introduction to human metabolomic investigations	26
Uncovering the muscle clock–mitochondria axis through exercise	26
Creating a picture of brown fat with creatine-CEST	25
Gut microbiota controlling radiation-induced enteritis and intestinal regeneration	25
Recompensation in MASLD-related cirrhosis via metabolic bariatric surgery	25
Subscription and Copyright Information	24
The sphinx helps to answer the riddle of cardiac regeneration	24
Targeting systemic and gut microbial metabolism in ER+ breast cancer	23
Subscription and Copyright Information	23
Subscription and Copyright Information	23
Dopamine	23
Metabolic consequences of sleep and circadian disruption during pregnancy and postpartum	23
Wildfires and COVID-19: syndemic impact on maternal and child health	23
Exploring tryptophan metabolism in cardiometabolic diseases	23
Detection, mechanisms, and therapeutic implications of oncometabolites	23
Spatiotemporal coordination between local flux and systemic homeostasis in the small intestine	23
Cortisol and cardiometabolic disease: a target for advancing health equity	22
Endoscopic management of obesity and metabolic diseases	22
Melatonin	22
Metabolic homeostasis of tissue macrophages across the lifespan	22
Gut feelings on short-chain fatty acids to regulate respiratory health	22
Road map for personalized exercise medicine in T2DM	22
An orphan to the rescue of obesity and steatotic liver?	21
Rethinking ‘normal’: are pubertal milestones and growth charts obsolete?	21
Systemic and organ-specific anti-inflammatory effects of sodium-glucose cotransporter-2 inhibitors	20
The relationship between CD4+ T cell glycolysis and their functions	20
The time is now for new, lower diabetes diagnostic thresholds	20
Assessment and treatment of osteoporosis and fractures in type 2 diabetes	19
Dietary and pharmacological energy restriction and exercise for healthspan extension	19
Apolipoprotein E in lipid metabolism and neurodegenerative disease	19
SIRT6: therapeutic target for nonalcoholic fatty liver disease	18
Understanding lactate sensing and signalling	18
Subscription and Copyright Information	18
Insulin	18
Subscription and Copyright Information	18
The impact of epitranscriptomic modifications on liver disease	17
Pancreatic islet adaptation in pregnancy and postpartum	17
Early nutritional interventions for chronic low-grade inflammation	17
NAD augmentation as a disease-modifying strategy for neurodegeneration	17
Advisory Board and Contents	16
Neural stem cell metabolism revisited: a critical role for mitochondria	16
Regulated cell death in myocardial ischemia–reperfusion injury	16
Decoding microbial volatile signals in host–microbiome crosstalk	16
Pathophysiology of human mitochondrial tRNA metabolism	16
Glucokinase activity in diabetes: too much of a good thing?	16
Mitochondrial quality control pathways sense mitochondrial protein import	16
Microglial metabolic flexibility: emerging roles for lactate	16