OOIR: Observatory of International Research

Papers

(The TQCC of Trends in Endocrinology and Metabolism is 17. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
N6-methyladenosine RNA modification in nonalcoholic fatty liver disease	592
Contribution of metabolism-independent glucose sensing to metabolic homeostasis	323
Maternal metabolism influences neural tube closure	215
Advisory Board and Contents	213
Advisory Board and Contents	210
How does mitochondrial import machinery fine-tune mitophagy? Different paths and one destination	155
Muscle regeneration: myofibers and fat jostle for position	119
Establishing evidence for immune surveillance of β-cell senescence	109
Cannabinoids and terpenes for diabetes mellitus and its complications: from mechanisms to new therapies	101
Methionine restriction and mimetics to ameliorate human aging and disease	101
Irisin limits amyloid-β buildup in Alzheimer’s disease	101
H19 long noncoding RNA in maternal obesity-driven metabolic programming	99
Unveiling the cancer risk nexus of the steatotic liver	96
Mechanisms of kidney fibrosis and routes towards therapy	93
Neuroendocrine gut–brain signaling in obesity	93
Subscription and Copyright Information	90
Advisory Board and Contents	84
Cellular mechanism of diabetes remission by bariatric surgery	84
Glucocorticoids mediate fasting efficacy in breast cancer	82
Gut dysbiosis-mediated platelet activation as MASLD and cardiovascular disease link	80
Uridine	75
Dietary medium-chain triacylglycerols in metabolic regulation	75
Subscription and Copyright Information	72
Advisory Board and Contents	70
Advisory Board and Contents	68

Increased hepatic gluconeogenesis and type 2 diabetes mellitus	66
Interplays and functional divergences of one-carbon metabolic shunts	66
Healthy choices, healthy futures: promoting healthy nutrition to curb non-communicable diseases	62
Why cells need iron: a compendium of iron utilisation	60
A matter of time: temporal structure and functional relevance of macrophage metabolic rewiring	59
Enhancer binding as a KEysTONE of fasting response	57
Effects of APOE4 on omega-3 brain metabolism across the lifespan	56
Parathyroid hormone–PTH1R signaling in cardiovascular disease and homeostasis	56
Subscription and Copyright Information	55
Subscription and Copyright Information	55
Metabolic remodeling in cancer and senescence and its therapeutic implications	55
Advisory Board and Contents	54
The landscape of fetus metabolism in maternal hyperglycemia	53
Advisory Board and Contents	53
‘Rotor free-wheeling’ in impaired F1FO-ATPase induces congenital hypermetabolism	49
Subscription and Copyright Information	48
Subscription and Copyright Information	48
Subscription and Copyright Information	48
Mechanomedicine targeting brown adipose tissue for metabolic health	46
Beta-hydroxybutyrate	46
Drosophila as a diet discovery tool for treating amino acid disorders	46
Glucose-dependent insulinotropic polypeptide (GIP)	46
Liver-expressed antimicrobial peptide 2 (LEAP2)	45
GLP-1 agonists: superior for mind and body in antipsychotic-treated patients?	45
A double-edged sword: risks and benefits of heat for human health	44
Cholesterol–LXR axis in metabolic regulation of liver fibrosis and hepatocarcinogenesis	43
A metabolic perspective on cuproptosis	42
A multidimensional epidemiological perspective on frailty dynamics and prevention	41
CD8+ T cell stressors converge on shared metabolic–epigenetic networks	40
Advisory Board and Contents	39
Metabolism, homeostasis, and aging	39
Current status and future perspectives of FGF21 analogues in clinical trials	39
Do metabolic fluxes change with age?	39
Metabolic challengers selecting tumor-persistent cells	39
Can kisspeptin be a new treatment for sexual dysfunction?	38
Targeting cholesterol-dependent adrenal steroidogenesis for management of primary aldosteronism	38
The interplay between endometriosis and obesity	38
Mitochondrial copper in human genetic disorders	38
Hallmarks of the metabolic secretome	37
Gut microbiota and eating behaviour in circadian syndrome	37
Polyamines	36
Exercise pills for cardiometabolic health cannot mimic the exercise milieu	36
Pregnancy-induced metabolic reprogramming and regenerative responses to pro-aging stresses	35
Improving incretin-mediated body weight loss via energy expenditure	35
MetALD at the crossroads of metabolic and alcohol-related liver disease	35
Advisory Board and Contents	33
Balancing metabolism and regeneration in liver diseases through HNF4α targeting	32
Serine signaling governs metabolic homeostasis and health	32
Lipid-associated macrophages between aggravation and alleviation of metabolic diseases	31
Per- and polyfluoroalkyl substances as persistent pollutants with metabolic and endocrine-disrupting impacts	31

Advisory Board and Contents	31
New tools for bone health assessment in secreting pituitary adenomas	31
Advisory Board and Contents	31
Shifting metabolism to increase lifespan	30
Regulation of skeletal muscle mitochondrial fuel utilization during exercise	30
Advisory Board and Contents	30
B vitamins as adjunct therapies for depressive disorder	29
Shared metabolic and stress pathways to neonatal adiposity	29
Rewiring of the glymphatic landscape in metabolic disorders	29
Single-cell imaging of liver metabolic dynamics using fluorescent biosensors	29
Targeting ferroptosis to halt MASLD and MASH	29
More trials for the unhappy hypothyroid patient on thyroxine: a clinician’s perspective	28
Blood-based bioenergetics: a liquid biopsy of mitochondrial dysfunction in disease	28
Exercised breastmilk: a kick-start to prevent childhood obesity?	28
Insights from omics research on plant-based diets and cardiometabolic health	28
A three-layer perspective on miRNA regulation in β cell inflammation	28
Advisory Board and Contents	28
The physiological functions of lymphangiocrine signals	27
Mitochondria as sensors of intracellular pathogens	27
Recompensation in MASLD-related cirrhosis via metabolic bariatric surgery	27
The immunoregulatory role of progesterone during embryo implantation and pregnancy	26
(Poly)phenols as bioactive constituents linked to dietary fibre metabolic fate	26
An epidemiological introduction to human metabolomic investigations	26
Uncovering the muscle clock–mitochondria axis through exercise	26
Cardioprotective benefits of metabolic surgery and GLP-1 receptor agonist–based therapies	26
Gut microbiota controlling radiation-induced enteritis and intestinal regeneration	25
Metabolic-immune microenvironment crosstalk mediating ICI resistance in MASH-HCC	25
Metabolic consequences of sleep and circadian disruption during pregnancy and postpartum	24
Creating a picture of brown fat with creatine-CEST	24
Subscription and Copyright Information	24
Subscription and Copyright Information	24
The sphinx helps to answer the riddle of cardiac regeneration	24
Wildfires and COVID-19: syndemic impact on maternal and child health	23
Targeting systemic and gut microbial metabolism in ER+ breast cancer	23
Brown adipose tissue and beyond: lipolysis and glycerolipid cycling in thermogenesis	23
Lipid signaling networks in pancreatic cancer progression and therapeutic perspectives	23
Endoscopic management of obesity and metabolic diseases	22
Heme as a metabolic cell-fate switch	21
Detection, mechanisms, and therapeutic implications of oncometabolites	21
Road map for personalized exercise medicine in T2DM	21
Exploring tryptophan metabolism in cardiometabolic diseases	20
Metabolic homeostasis of tissue macrophages across the lifespan	20
Cortisol and cardiometabolic disease: a target for advancing health equity	19
The relationship between CD4+ T cell glycolysis and their functions	19
Acetate	19
Apolipoprotein E in lipid metabolism and neurodegenerative disease	19
Gut feelings on short-chain fatty acids to regulate respiratory health	19
Spatiotemporal coordination between local flux and systemic homeostasis in the small intestine	19
Dopamine	19
Understanding lactate sensing and signalling	19
Dietary and pharmacological energy restriction and exercise for healthspan extension	18
Melatonin	18
Mitochondrial NADP(H) integrates redox and metabolism	18
An orphan to the rescue of obesity and steatotic liver?	18
LIFe of the sugar-free party in cancer metabolism	18
Systemic and organ-specific anti-inflammatory effects of sodium-glucose cotransporter-2 inhibitors	18
Rethinking ‘normal’: are pubertal milestones and growth charts obsolete?	18
Assessment and treatment of osteoporosis and fractures in type 2 diabetes	18
Glucokinase activity in diabetes: too much of a good thing?	17
Neural stem cell metabolism revisited: a critical role for mitochondria	17
Subscription and Copyright Information	17
Insulin	17
Pancreatic islet adaptation in pregnancy and postpartum	17
Subscription and Copyright Information	17
The impact of epitranscriptomic modifications on liver disease	17
SIRT6: therapeutic target for nonalcoholic fatty liver disease	17