OOIR: Observatory of International Research

Papers

(The median citation count of Molecular and Cellular Neuroscience is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
Impaired hippocampal neurogenesis and cognitive performance in adult DBC1-knock out mice	65
Immunomodulatory protein from ganoderma microsporum protects against oxidative damages and cognitive impairments after traumatic brain injury	56
Cannabinoid receptor 2 agonist AM1241 alleviates epileptic seizures and epilepsy-associated depression via inhibiting neuroinflammation in a pilocarpine-induced chronic epilepsy mouse model	55
Exosome-based therapeutics: Advancing drug delivery for neurodegenerative diseases	42
Absence of Gem1 (mammalian Miro/Rhot) mitigates alpha-synuclein toxicity in a yeast model of Parkinson's disease	40
Reduced platelet activation and thrombus formation in male transgenic model mice of Alzheimer's disease suggests early sex-specific differences in platelet pathophysiology	36
Signatures of cochlear processing in neuronal coding of auditory information	30
Sex differences in susceptibility to substance use disorder: Role for X chromosome inactivation and escape?	27
Methylation at a conserved lysine residue modulates tau assembly and cellular functions	27
The role of alarmins in neuroinflammation following spinal cord injury: A systematic review of the literature	27
Multi-level computational analysis identifies schizophrenia missense SNPs with implications for synaptic function, neuroimmune dysfunction, and antipsychotic response	27
Alpha-secretase dependent nuclear localization of the amyloid-β precursor protein-binding protein Fe65 promotes DNA repair	25
Paternal morphine exposure in rats reduces social play in adolescent male progeny without affecting drug-taking behavior in juvenile males or female offspring	24
TREM2 in Alzheimer's disease: Structure, function, therapeutic prospects, and activation challenges	23
Irisin regulates mitochondrial function to support synaptogenesis in the developing hippocampus	23
Suppression of BMP signaling restores mitral cell development impaired by FGF signaling deficits in mouse olfactory bulb	22
Dimethyl itaconate reprograms neurotoxic to neuroprotective primary astrocytes through the regulation of NLRP3 inflammasome and NRF2/HO-1 pathways	22
Eprosartan alleviates the traumatic brain injury-induced multi-organ dysfunction syndrome in mice via AT1R/SNS/HMGB1 blockade and PDL-1 modulation	21
Astrocytes initiate autophagic flux and maintain cell viability after internalizing non-active native extracellular α-synuclein	21
Combined treatment of retinoic acid with olfactory ensheathing cells protect gentamicin-induced SGNs damage in the rat cochlea in vitro	21
TAT-PPA1 protects against oxidative stress-induced loss of dopaminergic neurons	21
In vivo neuroplasticity in vestibular animal models	20
Protein phosphatases regulate the formation of Müller glia-derived progenitor cells in the chick retina	18
Activation of angiotensin converting enzyme 2 promotes hippocampal neurogenesis via activation of Wnt/β-catenin signaling in hypertension	18
Surface translocation of Kir2.1 channel induces IL-1β secretion in microglia	18

The role of calcium, Akt and ERK signaling in cadmium-induced hair cell death	17
iPSC-derived healthy human astrocytes selectively load miRNAs targeting neuronal genes into extracellular vesicles	16
Interneurons in the CA1 stratum oriens expressing αTTP may play a role in the delayed-ageing Pol μ mouse model	15
Neuroprotective effect of the peroxisome proliferator-activated receptor γ agonist lobeglitazone following intracerebral hemorrhage in rats	15
GSK-3β dysregulation in aging: Implications for tau pathology and Alzheimer's disease progression	15
Editorial Board	15
Transcriptional and epigenetic regulation of microglia in substance use disorders	15
An in-depth association analysis of genetic variants within nicotine-related loci: Meeting in middle of GWAS and genetic fine-mapping	14
Antidepressant-like effect of CP-101,606: Evidence of mTOR pathway activation	14
Chemogenetic inhibition of TrkB signalling reduces phrenic motor neuron survival and size	14
The mRNA expression profile of glycine receptor subunits alpha 1, alpha 2, alpha 4 and beta in female and male mice	13
Acute stress uncovers latent β2-adrenergic receptor and Corticotropin Releasing Factor interactions in the ventral Bed Nucleus of the Stria Terminalis critical for long-term stress-avoidance behavior	13
Vulnerability of neurofilament-expressing neurons in frontotemporal dementia	13
Synaptic logistics: Competing over shared resources	13
Golgi stress induces upregulation of the ER-Golgi SNARE Syntaxin-5, altered βAPP processing, and Caspase-3-dependent apoptosis in NG108-15 cells	13
The glymphatic and meningeal lymphatic systems may converge, connecting traumatic brain injury progression with chronic traumatic encephalopathy onset	13
In vitro and in vivo models: What have we learnt about inner ear regeneration and treatment for hearing loss?	12
Apelin-13 can regulate adipose-derived mesenchymal stem cells to improve traumatic brain injury	12
Distinct subpopulations of D1 medium spiny neurons exhibit unique transcriptional responsiveness to cocaine	12
Turnover of synaptic adhesion molecules	12
Expanded polyQ aggregates interact with sarco-endoplasmic reticulum calcium ATPase and Drosophila inhibitor of apoptosis protein1 to regulate polyQ mediated neurodegeneration in Drosophila	12
Role of ALS-associated OPTN-K489E mutation in neuronal cell-death regulation	12
Recovery of Angelman syndrome rat deficits with UBE3A protein supplementation	12
Select NSAIDs enhance peripheral nerve growth and calcium signaling through PPARγ activation	12
Comparing effects of microgravity and amyotrophic lateral sclerosis in the mouse ventral lumbar spinal cord	11
Peroxisome, neuropeptide, and inflammation signaling pathways uniquely impacted by opioid exposure in the hypothalamus of males and females	11
Glycogen phosphorylase isoenzyme GPbb versus GPmm regulation of ventromedial hypothalamic nucleus glucoregulatory neurotransmitter and counter-regulatory hormone profiles during hypoglycemia: Role of	11
A critical role for the fascin family of actin bundling proteins in axon development, brain wiring and function	11
haFGF14–154 attenuates Aβ1–42-induced neurotoxicity by facilitating BDNF maturation in a neuron-astrocyte co-culture system	10
Compartment specific mitochondrial dysfunction in Drosophila knock-in model of ALS reversed by altered gene expression of OXPHOS subunits and pro-fission factor Drp1	10
Efferent axons in the zebrafish lateral line degenerate following sensory hair cell ablation	10
Interrogating mediators of single-cell transcriptional changes in the acute damaged cerebral cortex: Insights into endothelial-astrocyte interactions	9
AstroGreen transgenic mouse illuminates the trafficking of astrocyte-derived extracellular vesicles	9
The extracellular domain of mGluR6 regulates targeting to the conventional secretion pathway	9
CRMP2 conditional knockout changes axonal function and ultrastructure of axons in mice corpus callosum	9
Editorial Board	9
RNA-based therapies for neurodegenerative disease: Targeting molecular mechanisms for disease modification	9
A microglial kinase ITK mediating neuroinflammation and behavioral deficits in traumatic brain injury	9
Editorial Board	9
A neural mass model for disturbance of alpha rhythm in the minimal hepatic encephalopathy	9
Bridging the gap in the management of Alzheimer's disease using fecal microbiota transplantation	9
VPS35 deficiency in the embryonic cortex leads to prenatal cell loss and abnormal development of axonal connectivity	9
The elastin-derived peptide (VGVAPG) activates autophagy in neuroblastoma (SH-SY5Y) cells via peroxisome proliferator-activated receptor gamma (PPARγ)	9
Editorial Board	8
The Npc2 mouse signifies pathological changes comparable to human Niemann-Pick type C2 disease	8
Stable apelin-13 analogues promote cell proliferation, differentiation and protect inflammation induced cell death	8
Expression of the human herpesvirus 6A latency-associated transcript U94A impairs cytoskeletal functions in human neural cells	8
Polygenic influences on the behavioral effects of alcohol withdrawal in a mixed-ancestry population from the collaborative study on the genetics of alcoholism (COGA)	8
Interweaving microglial senescence and gut microbiome dynamics in Alzheimer's disease – Mechanisms and therapeutic frontiers	7
Knockdown of BMP7 induced oligodendrocyte apoptosis, demyelination and motor function loss	7

Glutamine metabolism in diseases associated with mitochondrial dysfunction	7
The exocyst subunit Sec15 is critical for proper synaptic development and function at the Drosophila NMJ	7
microRNA-146a modulates behavioural activity, neuroinflammation, and oxidative stress in adult mice	7
Editorial Board	7
Recovery of motor function is associated with rescue of glutamate biomarkers in the striatum and motor cortex following treatment with Mucuna pruriens in a murine model of Parkinsons disease	7
Special issue: Synaptic logistics — Maintenance of synaptic composition, properties and function	7
Erratum to “wild type and P301L mutant Tau promote neuro-inflammation and α-Synuclein accumulation in lentiviral gene delivery models” [Mol. Cell. Neurosci. 49 (1) (2012), 44–53]	7
Molecular mechanisms of AMPAR reversible stabilization at synapses	7
Neuronal endoplasmic reticulum architecture and roles in axonal physiology	7
Cdc42 activation is necessary for heterosynaptic cooperation and competition	7
Genetic modifiers of epilepsy: A narrative review	6
Glutathione S-transferase: A keystone in Parkinson's disease pathogenesis and therapy	6
Systemic inflammation activates coagulation and immune cell infiltration pathways in brains with propagating α-synuclein fibril aggregates	6
BDNF-modified human umbilical cord mesenchymal stem cells-derived dopaminergic-like neurons improve rotation behavior of Parkinson's disease rats through neuroprotection and anti-neuroinflammation	6
Covalent inhibitors in Parkinson's disease: Molecular targeting strategies for neuroprotective intervention	6
Editorial Board	6
Experience-dependent Tip60 nucleocytoplasmic transport is regulated by its NLS/NES sequences for neuroplasticity gene control	6
Heparan sulfate proteoglycans: Mediators of cellular and molecular Alzheimer's disease pathogenic factors via tunnelling nanotubes?	6
Editorial Board	6
Identifying targets to prevent aminoglycoside ototoxicity	6
Hyperactivity of Purkinje cell and motor deficits in C9orf72 knockout mice	6
Pharmacological regulation of adult brain neuroplasticity: Synergistic roles of neuropeptide signaling, psychedelics, and synaptic modulators	6
Cardiolipin released by microglia can act on neighboring glial cells to facilitate the uptake of amyloid-β (1–42)	6
The role of polarization dynamics in macrophages and microglia on the inflammatory microenvironment of spinal cord injury	5
Ubiquitous calpastatin overexpression in brain-injured mice attenuates motor and cognitive behavioral deficits without overt neuroprotection	5
Single subanesthetic dose of ketamine exerts antioxidant and antidepressive-like effect in ACTH-induced preclinical model of depression	5
Proteomic characterization of spinal cord synaptoneurosomes from Tg-SOD1/G93A mice supports a role for MNK1 and local translation in the early stages of amyotrophic lateral sclerosis	5
Activation of the unfolded protein response by Connexin47 mutations associated with Pelizaeus-Merzbacher-like disease	5
Circular RNA regulation and function in drug seeking phenotypes	5
Cypin binds to tubulin heterodimers and microtubule protofilaments and regulates microtubule spacing in developing hippocampal neurons	5
A novel in vitro model for investigating oligodendroglial maturation and myelin deposition under demyelinating and remyelinating conditions: Impact of microglial depletion and repopulation	5
Interleukin-4 activates divergent cell-intrinsic signals to regulate retinal cell proliferation induced by classical growth factors	5
Computational insights into mRNA and protein dynamics underlying synaptic plasticity rules	5
Editorial Board	5
Cyclosporine A (CsA) prevents synaptic impairment caused by truncated tau by caspase-3	5
Editorial Board	5
Editorial Board	5
Sex-dependent effects of monomeric α-synuclein on calcium and cell death of lateral hypothalamic mouse neurons are altered by orexin	5
Alpha-synuclein pathology is associated with astrocyte senescence in a midbrain organoid model of familial Parkinson's disease	5
Editorial Board	4
RBM15 relies on m6A modification to inhibit UBE2C, alleviating hippocampal neuronal injury by limiting microglial inflammation	4
Disease modifying effects of the amyloid-beta protofibril-selective antibody mAb158 in aged Tg2576 transgenic mice	4
Modulation of Nrf-2/HO-1/HIF-1α/TFAM pathways by Arbutin in rat model of cerebral ischemic stroke	4
Protein transport from pre- and postsynapse to the nucleus: Mechanisms and functional implications	4
β-Hydroxybutyrate enhances astrocyte glutamate uptake through EAAT1 expression regulation	4
Synaptic transmission at the vestibular hair cells of amniotes	4
Regulation of hippocampal excitatory synapse development by the adhesion G-protein coupled receptor brain-specific angiogenesis inhibitor 2 (BAI2/ADGRB2)	4
Taurine inhibits KDM3a production and microglia activation in lipopolysaccharide-treated mice and BV-2 cells	4
Microfluidics in neural extracellular vesicles characterization for early Alzheimer's disease diagnosis	4
Synaptic logistics: The presynaptic scaffold protein Piccolo a nodal point tuning synaptic vesicle recycling, maintenance and integrity	4
Effect of germ-free status on transcriptional profiles in the nucleus accumbens and transcriptomic response to chronic morphine	4
Early life adversity: Epigenetic regulation underlying drug addiction susceptibility	4
β2-adrenoceptor agonist formoterol attenuates NLRP3 inflammasome activation and GSDMD-mediated pyroptosis in microglia through enhancing IκBα/NF-κB inhibition, SQSTM1/p62-dependent selective autophagy	4
Profiling transcriptomic responses of human stem cell-derived medium spiny neuron-like cells to exogenous phasic and tonic neurotransmitters	4
4-MEC potentially triggers CAV1 via the BDNF-TrkB signaling pathway	4
Long-term effects of amyloid-beta deposits in human iPSC-derived astrocytes	4
Identifying potential genes driving ferroptosis in the substantia nigra and dopaminergic neurons in Parkinson's disease	4
DAPK1 induces motor neuron apoptosis in hSOD1G93A-linked amyotrophic lateral sclerosis via regulating the Xiap/JNK pathway	4
Mitochondrial fission and fusion in neurodegenerative diseases:Ca2+ signalling	4
Biased 5-HT1A receptor agonists F13714 and NLX-101 differentially affect pattern separation and neuronal plasticity in rats after acute and chronic treatment	4