OOIR: Observatory of International Research

Papers

(The median citation count of Molecular and Cellular Neuroscience is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)

Article	Citations
Immunomodulatory protein from ganoderma microsporum protects against oxidative damages and cognitive impairments after traumatic brain injury	80
Editorial Board	50
Impaired hippocampal neurogenesis and cognitive performance in adult DBC1-knock out mice	41
Cannabinoid receptor 2 agonist AM1241 alleviates epileptic seizures and epilepsy-associated depression via inhibiting neuroinflammation in a pilocarpine-induced chronic epilepsy mouse model	32
Editorial Board	27
Exosome-based therapeutics: Advancing drug delivery for neurodegenerative diseases	26
Signatures of cochlear processing in neuronal coding of auditory information	25
Methylation at a conserved lysine residue modulates tau assembly and cellular functions	23
Parvalbumin subtypes of cerebellar Purkinje cells contribute to differential intrinsic firing properties	22
Absence of Gem1 (mammalian Miro/Rhot) mitigates alpha-synuclein toxicity in a yeast model of Parkinson's disease	22
Reduced platelet activation and thrombus formation in male transgenic model mice of Alzheimer's disease suggests early sex-specific differences in platelet pathophysiology	21
Alpha-secretase dependent nuclear localization of the amyloid-β precursor protein-binding protein Fe65 promotes DNA repair	20
Suppression of BMP signaling restores mitral cell development impaired by FGF signaling deficits in mouse olfactory bulb	20
Dimethyl itaconate reprograms neurotoxic to neuroprotective primary astrocytes through the regulation of NLRP3 inflammasome and NRF2/HO-1 pathways	20
TREM2 in Alzheimer's disease: Structure, function, therapeutic prospects, and activation challenges	19
Sex differences in susceptibility to substance use disorder: Role for X chromosome inactivation and escape?	19
Paternal morphine exposure in rats reduces social play in adolescent male progeny without affecting drug-taking behavior in juvenile males or female offspring	19
The role of alarmins in neuroinflammation following spinal cord injury: A systematic review of the literature	18
Differential expression of the neuronal CB1 cannabinoid receptor in the hippocampus of male Ts65Dn Down syndrome mouse model	18
Combined treatment of retinoic acid with olfactory ensheathing cells protect gentamicin-induced SGNs damage in the rat cochlea in vitro	17
Surface translocation of Kir2.1 channel induces IL-1β secretion in microglia	17
Protein phosphatases regulate the formation of Müller glia-derived progenitor cells in the chick retina	16
Astrocytes initiate autophagic flux and maintain cell viability after internalizing non-active native extracellular α-synuclein	16
In vivo neuroplasticity in vestibular animal models	16
The role of calcium, Akt and ERK signaling in cadmium-induced hair cell death	16

TAT-PPA1 protects against oxidative stress-induced loss of dopaminergic neurons	15
GSK-3β dysregulation in aging: Implications for tau pathology and Alzheimer's disease progression	14
Editorial Board	14
Activation of angiotensin converting enzyme 2 promotes hippocampal neurogenesis via activation of Wnt/β-catenin signaling in hypertension	14
Transcriptional and epigenetic regulation of microglia in substance use disorders	14
Interneurons in the CA1 stratum oriens expressing αTTP may play a role in the delayed-ageing Pol μ mouse model	14
iPSC-derived healthy human astrocytes selectively load miRNAs targeting neuronal genes into extracellular vesicles	14
Synaptic logistics: Competing over shared resources	13
Identification of novel Aβ-LilrB2 inhibitors as potential therapeutic agents for Alzheimer's disease	13
Antidepressant-like effect of CP-101,606: Evidence of mTOR pathway activation	13
An in-depth association analysis of genetic variants within nicotine-related loci: Meeting in middle of GWAS and genetic fine-mapping	13
Chemogenetic inhibition of TrkB signalling reduces phrenic motor neuron survival and size	13
Recovery of Angelman syndrome rat deficits with UBE3A protein supplementation	12
Expanded polyQ aggregates interact with sarco-endoplasmic reticulum calcium ATPase and Drosophila inhibitor of apoptosis protein1 to regulate polyQ mediated neurodegeneration in Drosophila	12
The mRNA expression profile of glycine receptor subunits alpha 1, alpha 2, alpha 4 and beta in female and male mice	11
Turnover of synaptic adhesion molecules	11
Role of ALS-associated OPTN-K489E mutation in neuronal cell-death regulation	11
Distinct subpopulations of D1 medium spiny neurons exhibit unique transcriptional responsiveness to cocaine	11
Vulnerability of neurofilament-expressing neurons in frontotemporal dementia	11
In vitro and in vivo models: What have we learnt about inner ear regeneration and treatment for hearing loss?	11
Glycogen phosphorylase isoenzyme GPbb versus GPmm regulation of ventromedial hypothalamic nucleus glucoregulatory neurotransmitter and counter-regulatory hormone profiles during hypoglycemia: Role of	10
Artesunate restores the levels of inhibitory synapse proteins and reduces amyloid-β and C-terminal fragments (CTFs) of the amyloid precursor protein in an AD-mouse model	10
Comparing effects of microgravity and amyotrophic lateral sclerosis in the mouse ventral lumbar spinal cord	10
Golgi stress induces upregulation of the ER-Golgi SNARE Syntaxin-5, altered βAPP processing, and Caspase-3-dependent apoptosis in NG108-15 cells	10
Compartment specific mitochondrial dysfunction in Drosophila knock-in model of ALS reversed by altered gene expression of OXPHOS subunits and pro-fission factor Drp1	10
Efferent axons in the zebrafish lateral line degenerate following sensory hair cell ablation	9
RNA-based therapies for neurodegenerative disease: Targeting molecular mechanisms for disease modification	9
Editorial Board	9
Activity-dependent circuitry plasticity via the regulation of the histamine receptor level in the Drosophila visual system	9
Peroxisome, neuropeptide, and inflammation signaling pathways uniquely impacted by opioid exposure in the hypothalamus of males and females	9
VPS35 deficiency in the embryonic cortex leads to prenatal cell loss and abnormal development of axonal connectivity	8
Interrogating mediators of single-cell transcriptional changes in the acute damaged cerebral cortex: Insights into endothelial-astrocyte interactions	8
Editorial Board	8
Effects of TDP-43 overexpression on neuron proteome and morphology in vitro	8
A neural mass model for disturbance of alpha rhythm in the minimal hepatic encephalopathy	8
microRNA-146a modulates behavioural activity, neuroinflammation, and oxidative stress in adult mice	7
Corrigendum to “Neurotoxic effects of MPTP on mouse cerebral cortex: Modulation of neuroinflammation as a neuroprotective strategy” [Mol. Cell. Neurosci., Volume 96, April 2019, Pages 1–9.]	7
Alpha-synuclein negatively controls cell proliferation in dopaminergic neurons	7
Olfactory receptor coding sequences cause silencing of episomal constructs in multiple cell lines	7
Polygenic influences on the behavioral effects of alcohol withdrawal in a mixed-ancestry population from the collaborative study on the genetics of alcoholism (COGA)	7
Expression of the human herpesvirus 6A latency-associated transcript U94A impairs cytoskeletal functions in human neural cells	7
Neuronal endoplasmic reticulum architecture and roles in axonal physiology	7
Erratum to “wild type and P301L mutant Tau promote neuro-inflammation and α-Synuclein accumulation in lentiviral gene delivery models” [Mol. Cell. Neurosci. 49 (1) (2012), 44–53]	7
Editorial Board	7
A microglial kinase ITK mediating neuroinflammation and behavioral deficits in traumatic brain injury	7
The elastin-derived peptide (VGVAPG) activates autophagy in neuroblastoma (SH-SY5Y) cells via peroxisome proliferator-activated receptor gamma (PPARγ)	7
Editorial Board	7
Molecular mechanisms of AMPAR reversible stabilization at synapses	7
Elevated soluble amyloid beta protofibrils in Down syndrome and Alzheimer's disease	7
CRMP2 conditional knockout changes axonal function and ultrastructure of axons in mice corpus callosum	7

Pharmacologic treatments in preclinical tinnitus models with special focus on Ginkgo biloba leaf extract EGb 761®	7
The Npc2 mouse signifies pathological changes comparable to human Niemann-Pick type C2 disease	7
Knockdown of BMP7 induced oligodendrocyte apoptosis, demyelination and motor function loss	6
Cardiolipin released by microglia can act on neighboring glial cells to facilitate the uptake of amyloid-β (1–42)	6
Editorial Board	6
The exocyst subunit Sec15 is critical for proper synaptic development and function at the Drosophila NMJ	6
Editorial Board	6
Special issue: Synaptic logistics — Maintenance of synaptic composition, properties and function	6
BDNF-modified human umbilical cord mesenchymal stem cells-derived dopaminergic-like neurons improve rotation behavior of Parkinson's disease rats through neuroprotection and anti-neuroinflammation	6
Identifying targets to prevent aminoglycoside ototoxicity	6
Glutamine metabolism in diseases associated with mitochondrial dysfunction	6
Recovery of motor function is associated with rescue of glutamate biomarkers in the striatum and motor cortex following treatment with Mucuna pruriens in a murine model of Parkinsons disease	6
Editorial Board	6
Cdc42 activation is necessary for heterosynaptic cooperation and competition	6
Altered hippocampal dendritic spine maturation after hypoxia-induced seizures in neonatal rats	5
GPR3 accelerates neurite outgrowth and neuronal polarity formation via PI3 kinase-mediating signaling pathway in cultured primary neurons	5
Operative list of genes associated with autism and neurodevelopmental disorders based on database review	5
Systemic inflammation activates coagulation and immune cell infiltration pathways in brains with propagating α-synuclein fibril aggregates	5
Hyperactivity of Purkinje cell and motor deficits in C9orf72 knockout mice	5
Glutathione S-transferase: A keystone in Parkinson's disease pathogenesis and therapy	5
The potential roles of excitatory-inhibitory imbalances and the repressor element-1 silencing transcription factor in aging and aging-associated diseases	5
Intermitochondrial signaling regulates the uniform distribution of stationary mitochondria in axons	5
Heparan sulfate proteoglycans: Mediators of cellular and molecular Alzheimer's disease pathogenic factors via tunnelling nanotubes?	5
LMK235, a small molecule inhibitor of HDAC4/5, protects dopaminergic neurons against neurotoxin- and α-synuclein-induced degeneration in cellular models of Parkinson's disease	5
Experience-dependent Tip60 nucleocytoplasmic transport is regulated by its NLS/NES sequences for neuroplasticity gene control	5
Proteomic characterization of spinal cord synaptoneurosomes from Tg-SOD1/G93A mice supports a role for MNK1 and local translation in the early stages of amyotrophic lateral sclerosis	4
Cypin binds to tubulin heterodimers and microtubule protofilaments and regulates microtubule spacing in developing hippocampal neurons	4
Editorial Board	4
Cyclosporine A (CsA) prevents synaptic impairment caused by truncated tau by caspase-3	4
Circular RNA regulation and function in drug seeking phenotypes	4
Editorial Board	4
Protein transport from pre- and postsynapse to the nucleus: Mechanisms and functional implications	4
Single subanesthetic dose of ketamine exerts antioxidant and antidepressive-like effect in ACTH-induced preclinical model of depression	4
A novel in vitro model for investigating oligodendroglial maturation and myelin deposition under demyelinating and remyelinating conditions: Impact of microglial depletion and repopulation	4
Alpha-synuclein pathology is associated with astrocyte senescence in a midbrain organoid model of familial Parkinson's disease	4
Synaptic transmission at the vestibular hair cells of amniotes	3
Activation of the unfolded protein response by Connexin47 mutations associated with Pelizaeus-Merzbacher-like disease	3
Sex-dependent effects of monomeric α-synuclein on calcium and cell death of lateral hypothalamic mouse neurons are altered by orexin	3
Effect of germ-free status on transcriptional profiles in the nucleus accumbens and transcriptomic response to chronic morphine	3
Profiling transcriptomic responses of human stem cell-derived medium spiny neuron-like cells to exogenous phasic and tonic neurotransmitters	3
iPSC-induced neurons with the V337M MAPT mutation are selectively vulnerable to caspase-mediated cleavage of tau and apoptotic cell death	3
β2-adrenoceptor agonist formoterol attenuates NLRP3 inflammasome activation and GSDMD-mediated pyroptosis in microglia through enhancing IκBα/NF-κB inhibition, SQSTM1/p62-dependent selective autophagy	3
Interleukin-4 activates divergent cell-intrinsic signals to regulate retinal cell proliferation induced by classical growth factors	3
Mitochondrial fission and fusion in neurodegenerative diseases:Ca2+ signalling	3
Early life adversity: Epigenetic regulation underlying drug addiction susceptibility	3
Amyloid-β precursor protein processing and oxidative stress are altered in human iPSC-derived neuron and astrocyte co-cultures carrying presenillin-1 gene mutations following spontaneous differentiati	3
Biased 5-HT1A receptor agonists F13714 and NLX-101 differentially affect pattern separation and neuronal plasticity in rats after acute and chronic treatment	3
Long-term effects of amyloid-beta deposits in human iPSC-derived astrocytes	3
Computational insights into mRNA and protein dynamics underlying synaptic plasticity rules	3
Editorial Board	3
β-Hydroxybutyrate enhances astrocyte glutamate uptake through EAAT1 expression regulation	3
Editorial Board	3
RBM15 relies on m6A modification to inhibit UBE2C, alleviating hippocampal neuronal injury by limiting microglial inflammation	3
Synaptic logistics: The presynaptic scaffold protein Piccolo a nodal point tuning synaptic vesicle recycling, maintenance and integrity	3