Genes Chromosomes & Cancer

Article	Citations
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Uncovering variable neoplasms between ATM protein‐truncating and common missense variants using 394 694 UK Biobank exomes	49
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Polymorphisms of the PD‐L1 gene 3′‐untranslated region are associated with the expression of PD‐L1 in non‐small cell lung cancer	38
ERG amplification is a secondary recurrent driver event in myeloid malignancy with complex karyotype and TP53 mutations	38
MDM4 amplification in atypical lipomatous tumors/well‐differentiated liposarcoma: Private event or alternative oncogenic mechanism?	25
Neonatal osteoblastic tumor with a novel PTBP1::FOSB fusion	24
An SS18::NEDD4 cutaneous spindled and epithelioid sarcoma: An hitherto unclassified cutaneous sarcoma, resembling epithelioid sarcoma with aggressive clinical behavior	23
Recurrent VGLL3 fusions define a distinctive subset of spindle cell rhabdomyosarcoma with an indolent clinical course and striking predilection for the head and neck	23
Insertion of the CXXC domain of KMT2A into YAP1: An unusual mechanism behind the formation of a chimeric oncogenic protein	23
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The somatic p.T81dup variant in AKT3 gene underlies a mild cerebral phenotype and expands the spectrum including capillary malformation and lateralized overgrowth	19
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Near complete remission of an inoperable pancreatic acinar cell carcinoma after BRAF‐/MEK‐inhibitor treatment—A case report and review of the literature	18
Fusion‐positive non‐small cell lung carcinoma: Biological principles, clinical practice, and diagnostic implications	18
Comprehensive Analyses of Somatic Copy Number Alterations and Mutations Based on the Adenoma–Carcinoma Sequence	18
Malignant peripheral nerve sheath tumor in children: A clinicopathologic and molecular study with parallels to the adult counterpart	17
ERRATUM	17
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Correction to “Temporal Trends and Regional Variability in BRAF and KRAS Genetic Testing in Denmark (2010–2022): Implications for Precision Medicine”	17
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ZFP64::NCOA3 gene fusion defines a novel subset of spindle cell rhabdomyosarcoma	16
Ewing sarcoma and related FET family translocation‐associated round cell tumors: A century of clinical and scientific progress	16

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Malignant Bone‐Forming Neoplasm With NIPBL::BEND2 Fusion	15
Assigning evidence to actionability: An introduction to variant interpretation in precision cancer medicine	15
Genomic profile analysis of leiomyomas with bizarre nuclei and fumarate hydratase deficient leiomyomas: Strengths, weaknesses, and limitations of array‐CGH interpretation	15
Aneurysmal bone cyst with an unusual clinical presentation and a novel VDR‐USP6 fusion	15
Acute megakaryoblastic leukemia with trisomy 3 and CBFA2T3::GLIS2: A case report	14
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VIM::KMT2A‐rearranged sarcomas: A report of two new cases confirming an entity with distinct histologic features	14
Epithelioid hemangioendothelioma (EHE) with WWTR1::TFE3 gene fusion, a novel fusion variant	14
EWSR1::SSX1 Fusion‐Driven Synovial Sarcoma: A Case Presentation and Review of the Literature	13
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A Clinicopathologic and Molecular Reappraisal of Myxoinflammatory Fibroblastic Sarcoma—A Controversial and Pathologically Challenging Low‐Grade Sarcoma	12
Low‐Level BCR::ABL1 Transcript at Diagnosis in Childhood Leukemia: A 10‐Year Single Institution Study	12
Structural Variant Analysis of Complex Karyotype Myelodysplastic Neoplasia Through Optical Genome Mapping	12
Novel MIR143HG::PLAG1 gene fusion identified in a rectal myxoid leiomyosarcoma	12
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Untying the Gordian knot of composite hemangioendothelioma: Discovery of novel fusions	11
The presence of a chromosomal abnormality in cytopenia without dysplasia identifies a category of high‐risk clonal cytopenia of unknown significance	11
Constitutional balanced translocations involving SMARCB1: A rare cause of rhabdoid tumor predisposition syndrome	11
3′RNA and whole‐genome sequencing of archival uterine leiomyomas reveal a tumor subtype with chromosomal rearrangements affecting either HMGA2, HMGA1, or PLAG1	11
Clear cell mesotheliomas with inactivating VHL mutations and near‐haploid genomic features	11
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Expanding the spectrum of mesenchymal neoplasms with NR1D1‐rearrangement	10
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A Bibliometric Analysis on the Risk Factors of Cancer	10
Digital pathology systems enabling quality patient care	10
Spindle Cell Rhabdomyosarcoma of the Prostate With ZFP64::NCOA2 Fusion	10
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Molecular investigation of ALK‐rearranged epithelioid fibrous histiocytomas identifies CLTC as a novel fusion partner and evidence of fusion‐independent transcripti	9
Undifferentiated sarcoma of bone with a round to epithelioid cell phenotype harboring a novel EWSR1‐SSX2 fusion identified by RNA‐based next‐generation sequencing	9
IDH‐negative chondrosarcoma with metachronous dedifferentiation only in the metastatic site—A diagnostic pitfall	9
A cloud‐based resource for genome coordinate‐based exploration and large‐scale analysis of chromosome aberrations and gene fusions in cancer	9
Issue Information	9
Influence of Cytogenetics on the Outcome of Patients With High‐Risk Myelodysplastic Syndrome Including Deletion 5q Treated With Azacitidine With or Without Lenalidomide	9
Fibromyxoid aSoft Tissue Tumor With PLAG1 Fusion—The First Case in an Adult Patient	9
RREB1::MRTFB fusion‐positive extra‐glossal mesenchymal neoplasms: A series of five cases expanding their anatomic distribution and highlighting significant morphological and phenotypic diversit	9
The Variable Genomic Landscape During Osteosarcoma Progression: Insights From a Longitudinal WGS Analysis	9
Identification of a novel SH3PXD2B::FER fusion in a case of plexiform myofibroblastic tumor and review of the literature	9
Whole genome duplication in oral squamous cell carcinoma in patients younger than 50 years: implications for prognosis and adverse clinicopathological factors	9
MicroRNA Expression in High‐Grade B‐Cell Lymphoma With 11q Aberration	8
A case of a lipoblastoma with EEF1A1::PLAG1 fusion and metaplastic ossification	8
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Prevalence and Reclassification of Genetic Variants in South African Populations with Breast Cancer	8
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Recurrent PTBP1::MAML2 fusions in composite hemangioendothelioma with neuroendocrine differentiation: A report of two cases involving neck lymph nodes	8
Gene amplification in neoplasia: A cytogenetic survey of 80 131 cases	8

Central nervous system sarcoma with ATXN1::DUX4 fusion expands the concept of CIC‐rearranged sarcoma	7
Rhabdomyosarcoma With EWSR1::NF2 Gene Fusion: A Case Report Potentially Expanding Its Genetic Spectrum	7
Loss of smarcad1a accelerates tumorigenesis of malignant peripheral nerve sheath tumors in zebrafish	7
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POU2AF3‐rearranged sarcomas: A novel tumor defined by fusions of EWSR1 or FUS to a gene formerly designated COLCA2	7
Tyrosine kinase‐altered spindle cell neoplasms with EGFR internal tandem duplications	7
Nanopore DNA Sequencing Detected Chromothripsis‐Induced PAFAH1B1::USP6 Rearrangement in Periosteal Solid Aneurysmal Bone Cyst Initially Diagnosed as Osteosarcoma	7
Identification of Rare EIF3E::RSPO2 Fusion in Recurrent and Aggressive Urachal Adenocarcinoma	7
Multiomics to investigate the mechanisms contributing to repression of PTPRC and SOCS2 in pediatric T‐ALL: Focus on miR‐363‐3p and promoter methylation	7
How to use AI in pathology	7
PMS2 or PMS2CL? Characterization of variants detected in the 3′ of the PMS2 gene	7
Gastroblastoma with a novel EWSR1‐CTBP1 fusion presenting in adolescence	7
Refined cytogenetic IPSS‐R evaluation by the use of SNP array in a cohort of 290 MDS patients	7
Ovarian germ cell tumor/mastocytosis with KIT mutation: A unique clinicopathological entity	7
Cryptic TCF3 fusions in childhood leukemia: Detection by RNA sequencing	7
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GLI1, CDK4, and MDM2 Co‐Amplification Gastric Plexiform Fibromyxoma: A Case Report and Literature Review	6
The novel KIT exon 11 germline mutation K558N is associated with gastrointestinal stromal tumor, mastocytosis, and seminoma development	6
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Infantile metastatic ependymoma with a novel molecular profile and favorable outcome to intensive chemotherapy without irradiation: Case‐based review	6
FIP1L1::PDGFRA Fusion in a Pediatric Patient Presenting With B‐Cell Lymphoblastic Leukemia	6
Adolescent presentation of FGFR1::EBF2 gene fusion mesenchymal tumor	6
A unique epithelioid vascular neoplasm of bone characterized by EWSR1/FUS‐NFATC1/2 fusions	6
Uncovering the WWTR1::NCOA2 Gene fusion in low‐grade myoepithelial‐rich neoplasm with HMGA2 expression: A case report	6
NovelHNRNPM::LEUTXfusion resulting from chromothripsis of chromosome 19 in a pediatric undifferentiated small round cell neoplasm	6
TAF15::NR4A3 gene fusion identifies a morphologically distinct subset of extraskeletal myxoid chondrosarcoma mimicking myoepithelial tumors	6
A novel IRF2BP2::CDX2 Gene fusion in digital intravascular myoepithelioma of soft tissue: An enigma!	6
Novel ACTB::FER Promoter Swap Fusion Characterizes Rare Superficial Myoid/Myofibroblastic Tumors	6
Alternative genetic alterations of MYC, BCL2, and/or BCL6 in high‐grade B‐cell lymphoma (HGBL) and diffuse large B‐cell lymphoma (DLBCL): Can we identify dif	6
Malignant Peripheral Nerve Sheath Tumor (MPNST) With Smooth Muscle Differentiation of the Uterus—A Case Report With Emphasis on Diagnostic Pitfalls and Value of DNA Methylation A	5
ALK‐rearranged Mesenchymal Neoplasms: A Report of 9 cases Further Expanding the Clinicopathologic Spectrum of Emerging Kinase Fusion Positive Group of Tumors	5
Calcifying Spindle Cell Soft Tissue Tumor With SOX10::PLAG1 Fusion: A Case Report of a Morphologically Distinctive and Potentially Novel Soft Tissue Tumor	5
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Merged testing for colorectal cancer syndromes and re‐evaluation of genetic variants improve diagnostic yield: Results from a nationwide prospective cohort	5
Gene fusions in gastrointestinal tract cancers	5
Germline variation in RASAL2 may predict survival in patients with RAS‐activated colorectal cancer	5
RBM10‐TFE3 fusions: A FISH‐concealed anomaly in adult renal cell carcinomas displaying a variety of morphological and genomic features: Comprehensive study of six novel cases	5
Survey of germline variants in cancer‐associated genes in young adults with colorectal cancer	5
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Corrigendum	5
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GAB1‐ABL1 fusions in tumors that have histologic overlap with NTRK‐rearranged spindle cell tumors	5
Cell Senescence and the Genetics of Melanoma Development	5
Neuregulin 1 (NRG1) fusion‐positive high‐grade spindle cell sarcoma: A distinct group of soft tissue tumors with metastatic potential	5
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Giemsa‐negative chromosome bands preferentially recombine in cancer‐associated translocations and gene fusions	5
Corrigendum	5
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Increased MYB alternative promoter usage is associated with relapse in acute lymphoblastic leukemia	4
Novel EWSR1::UBP1 fusion expands the spectrum of spindle cell rhabdomyosarcomas	4
MYH9::LTK Fusion in a Pediatric Acral Soft Tissue Spindle Cell Neoplasm	4
FGFR1 gene fusions in a subset of pediatric mesenchymal tumors: Expanding the genetic spectrum of tumors sharing histologic overlap with infantile fibrosarcoma and “NTRK<	4
Low‐grade endometrial stromal sarcoma‐like tumors in male with JAZF1 gene fusions	4
A case of spindle cell rhabdomyosarcoma with a ZFP64::NCOA3 fusion	4
Successful treatment with MEK‐inhibitor in a patient with NRAS‐related cutaneous skeletal hypophosphatemia syndrome	4
Metastasizing aneurysmal dermatofibroma initially diagnosed as angiosarcoma confirmed by CD63::PRKCD fusion gene detection with nanopore sequencing	4
A cutaneous epithelioid vascular tumor harboring a TPM3::ALK fusion	4
Recurrent NF1 gene variants and their genotype/phenotype correlations in patients with Neurofibromatosis type I	4
N‐terminus DUX4‐immunohistochemistry is a reliable methodology for the diagnosis of DUX4‐fused B‐lymphoblastic leukemia/lymphoma (N‐terminus DUX4 IHC for DUX4<	4
Expanding the spectrum of GLI1‐altered mesenchymal tumors—A high‐grade uterine sarcoma harboring a novel PAMR1::GLI1 fusion and literature review of GLI1‐altered mesenchyma	4
The clinicopathologic significance of NPM1 mutation and ability to detect mutated NPM1 by immunohistochemistry in non‐AML myeloid neoplasms	4
Complete mimicry: Rhabdomyosarcoma with FUS::TFCP2 fusion masquerading as carcinoma—diagnostic challenge and report of two cases	4
Sporadic Breast Angiosarcoma With MYC Amplification on Extrachromosomal Circular DNA Detected Using Nanopore Sequencing in an Adolescent Female	4
Soft‐tissue sarcoma with MN1‐BEND2 fusion: A case report and comparison with astroblastoma	4
GAB1::ABL1 fusions define a distinctive soft tissue neoplasm, with variable perineurial differentiation, and a predilection for children and young adults	4
Spindle cell neoplasms with novel LTK fusion – Expanding the spectrum of kinase fusion‐positive soft tissue tumors	4
Osteoblastoma of the thumb with a novel PRSS44::ALK fusion and literature review of osteoblastoma of hands and feet bones	4
Clinicopathologic and survival correlates of embryonal rhabdomyosarcoma driven by RAS/RAF mutations	4
DICER1‐mutated rhabdomyosarcoma of the ovary with teratoid features	3
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Changes on chromosome 11p15.5 as specific marker for embryonal rhabdomyosarcoma?	3
Distinct Signatures of Chromosomal Involvement in 59 251 Translocations Across 58 Tumor Types. A Novel Perspective	3
Shallow whole‐genome sequencing of bone marrow aspirates in myelodysplastic neoplasms: A retrospective comparison with cytogenetics	3
Corrigendum	3
A novel HNRNPH1::ERG rearrangement in aggressive acute myeloid leukemia	3
TFG::MET‐rearranged soft tissue tumor: A rare infantile neoplasm with a distinct low‐grade triphasic morphology	3
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Assessing acute myeloid leukemia susceptibility in rearrangement‐driven patients by DNA breakage at topoisomerase II and CCCTC‐binding factor/cohesin binding sites	3
Erratum	3
Malignant undifferentiated epithelioid neoplasms with MAML2 rearrangements: A clinicopathologic study of seven cases demonstrating a heterogenous entity	3

Characterization of Pediatric Acute Myeloid Leukemia With t(7;12)(q36;p13)	3
Development and validation of blood tumor mutational burden reference standards	3
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Novel HMGA2::COL14A1 Fusion Identified in Xanthogranulomatous Epithelial Tumor/Keratin‐Positive Giant Cell Tumor	3
A Novel JAK2 Fusion in T‐Cell Prolymphocytic Leukemia	3
Discovery of Cis‐Regulatory Mechanisms via Non‐Coding Mutations in Acute Lymphoblastic Leukemia	3
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Mismatch repair deficiency: The what, how and why it is important	3
Microsatellite Instability and Loss of Heterozygosity as Prognostic Markers in Oral Squamous Cell Carcinoma: Molecular Mechanisms, Detection Techniques, and Therapeutic Strategies	3
A Challenging Case of an Intraosseous Composite Hemangioendothelioma of the Occipital Bone With YAP1::FOXR1 Fusion	3
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Wholistic approach: Transcriptomic analysis and beyond using archival material for molecular diagnosis	3
Vanished MDM2 amplification in multiple recurrences of an irradiated poorly differentiated sarcoma with amplified TRIO::TERT fusion gene	3
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Typical, atypical and cryptic t(15;17)(q24;q21) (PML::RARA) observed in acute promyelocytic leukemia: A retrospective review of 831 patients with concurrent chromosome and PML::RARA dual	2
Comprehensive analyses of microRNA and mRNA expression in colorectal serrated lesions and colorectal cancer with a microsatellite instability phenotype	2
A case of FN1‐fused calcified chondroid mesenchymal neoplasm of the hand with novel FGFR3 partner gene	2
When molecular outsmarts morphology: Malignant ossifying fibromyxoid tumors masquerading as osteosarcomas, including a novel CREBZF::PHF1 fusion	2
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COL1A1::PDGFB fusion uterine sarcoma with a TERT promoter mutation	2
Spindle Cell Sarcoma With Novel JAZF1::NUDT5 Gene Fusion: Report of a Previously Undescribed Neoplasm	2
Single‐Cell Profiling of Mononuclear Cells Identifies Transcriptomics Signatures Differentiating Prostate Cancer From Benign Prostatic Hyperplasia	2
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A novel colony‐stimulating factor 1 (CSF1) translocation  involving human endogenous retroviral element in a tenosynovial giant cell tumor	2
FGFR2::TACC2 fusion as a novel KIT‐independent mechanism of targeted therapy failure in a multidrug‐resistant gastrointestinal stromal tumor	2
A novel t(X;21)(p11.4;q22.12) translocation adds to the role of BCOR and RUNX1 in myelodysplastic syndromes and acute myeloid leukemias	2
Complementary value of molecular analysis to expert review in refining classification of uncommon soft tissue tumors	2
Pediatric Fibromatosis Lacks the Internal Tandem Duplication of EGFR Seen in Congenital Mesoblastic Nephroma	2
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Methylation classifiers: Brain tumors, sarcomas, and what's next	2
Hereditary Colorectal Cancer and Polyposis Syndromes Caused by Variants in Uncommon Genes	2
Schwann Cells Deficient in Neurofibromin Lack Sensitivity to Their Biomechanical Microenvironment	2
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MicroRNA‐192‐5p inhibits migration of triple negative breast cancer cells and directly regulates RhoGTPaseactivating protein 19	2
A novel STRN3::PRKD1 fusion in a cribriform adenocarcinoma of salivary gland with high‐grade transformation	2
Genomic profiling of pleomorphic rhabdomyosarcoma reveals a genomic signature distinct from that of embryonal rhabdomyosarcoma	2
Sustained remission after ruxolitinib and chimeric antigen receptor T‐cell therapy bridged to a second allogeneic hematopoietic stem cell transplantation for relapsed Philadelphia chromosome‐like B‐ce	2
A novel HMGA2::KITLG fusion in a dedifferentiated liposarcoma with amplification of MDM2 and HMGA2	2
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Novel MED15::ATF1 fusion in a pediatric melanoma with spitzoid features and aggressive presentation	2
NR1D1::MAML1 epithelioid and spindle cell sarcoma mimicking pseudomyogenic hemangioendothelioma in core biopsy: A case report and review of the literature	2
Profiling Precursor microRNAs of Breast Cancer From Total RNA Sequencing Data to Gain Insights Into Their Roles and Prognostic Values	2
An Inflammatory Myofibroblastic Tumor With a Novel ALKV1180L Mutation Leading to Acquired Resistance to Tyrosine Kinase Inhibitors	2
Gene Expression Profiles of AHNAK2, DCSTAMP, FN1, and TERT Correlate With Mutational Status and Recurrence in Papillary Thyroid Carcinoma	2
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Clonal origin and genomic diversity in Lynch syndrome‐associated endometrial cancer with multiple synchronous tumors: Identification of the pathogenicity of MLH1 p.L582H	1
The novel finding of an FGFR1::TACC1 fusion in an undifferentiated spindle cell sarcoma of soft tissue with aggressive clinical course	1
An intraosseous myoepithelial carcinoma with a EWSR1::PBX3 fusion	1
Pediatric Mesenchymal Tumor With MN1::TAF3 Fusion	1
Transcriptomic profiles‐based approach to decode the role of miR‐122 in triple negative breast cancer	1
Pediatric Erythroid Sarcoma Diagnostically Confirmed by Identification of a Recurrent NFIA::CBFA2T3 Fusion	1
Segregation, immunohistochemical, molecular and functional analyses classify a novel missense variant in fumarate hydratase (FH) as pathogenic	1
The Transcriptomic and Gene Fusion Landscape of Pleomorphic Salivary Gland Adenomas	1
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17p13 (TP53) Deletions Are Associated With an Aggressive Phenotype but Unrelated to Patient Prognosis in Urothelial Bladder Carcinomas	1
Standardizing analysis of intra‐tumoral heterogeneity with computational pathology	1
Primary mediastinal large B‐cell lymphoma is characterized by large‐scale copy‐neutral loss of heterozygosity	1
Colibactin mutational signatures in NTHL1 tumor syndrome and MUTYH associated polyposis patients	1
High‐Grade Uterine Sarcoma: First Report of a MEIS2::FOXO4 Fusion	1
Novel PDGFRB Gene Fusions in Two Cases of Infantile Myofibromatosis	1
Rethinking cancer initiation: The role of large‐scale mutational events	1
Challenging Conventional Perceptions of Oncogenes and Tumor Suppressor Genes: A Comprehensive Analysis of Gene Expression Patterns in Cancer	1
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Constitutional and acquired genetic variants in ARID5B in pediatric B‐cell precursor acute lymphoblastic leukemia	1
Translocation carcinomas of the kidney	1
Precision Diagnostics in Myeloid Malignancies: Development and Validation of a National Capture‐Based Gene Panel	1
Targeted RNA sequencing in the routine clinical detection of fusion genes in salivary gland tumors	1
Related mechanisms, current treatments, and new perspectives in meningioma	1
Clinicopathologic and molecular correlates to neoadjuvant chemotherapy‐induced pathologic response in breast angiosarcoma	1
Gastrointestinal stromal tumors withBRAFgene fusions. A report of two cases showing low or absentKITexpression resulting in diagnostic pitfalls	1
Clinicopathological features and resistance mechanisms in HIP1‐ALK‐rearranged lung cancer: A multicenter study	1