Journal of Structural Biology

Article	Citations
Keratin intermediate filament chains in the European common wall lizard (Podarcis muralis) and a potential keratin filament crosslinker	771
Tropomyosin induces the synthesis of magnesian calcite in sea urchin spines	84
Allosteric inhibition of cytosolic NADP+-dependent isocitrate dehydrogenase by oxaloacetate	53
Determination of amino acids that favour the αL region using Ramachandran propensity plots. Implications for α-sheet as the possible amyloid intermediate	39
Exploring high-resolution cryo-ET and subtomogram averaging capabilities of contemporary DEDs	34
Disorder-to-order transition of Synaptobrevin-2: Tracing the conformational diversity of a synaptic SNARE protein	33
Spike protein fusion loop controls SARS-CoV-2 fusogenicity and infectivity	33
An exon-biased biophysical approach and NMR spectroscopy define the secondary structure of a conserved helical element within the HOTAIR long non-coding RNA	33
Comparative structural, biophysical, and receptor binding study of true type and wild type AAV2	33
Calcium carbonate deposition in the spicules of the sponge Heteropia glomerosa (Porifera, Calcarea)	32
High-resolution single-particle imaging at 100–200 keV with the Gatan Alpine direct electron detector	31
Deep Learning-based structure modelling illuminates structure and function in uncharted regions of β-solenoid fold space	31
ContinuousFlex: Software package for analyzing continuous conformational variability of macromolecules in cryo electron microscopy and tomography data	29
TomoAlign: A novel approach to correcting sample motion and 3D CTF in CryoET	28
Multishot tomography for high-resolution in situ subtomogram averaging	27
Locating cellular contents during cryoFIB milling using cellular secondary-electron imaging	27
Inter-Domain interactions Slow BoNT/A’s onset of action	27
Outside Front Cover	24
Studying protein–protein interactions: Latest and most popular approaches	24
Outside Front Cover	23
CorRelator: Interactive software for real-time high precision cryo-correlative light and electron microscopy	23
Interaction of berberine with different forms of DNA in human telomeric region	23
Cementum thickening leads to lower whole tooth mobility and reduced root stresses: An in silico study on aging effects during mastication	23
Comprehensive structural overview of the C-terminal ligand-binding domains of the TetR family regulators	22
Focused ion beam-SEM 3D study of osteodentin in the teeth of the Atlantic wolfish Anarhichas lupus	22

Isolation and reconstruction of cardiac mitochondria from SBEM images using a deep learning-based method	21
Editorial Board	21
It’s noisy out there! A review of denoising techniques in cryo-electron tomography	21
Transcriptome profiling of DPP stimulated DPSCs identifies the role of autophagy in odontogenic differentiation	19
Structural and kinetic analysis of the monofunctional Staphylococcus aureus PBP1	19
Crystal structure of TbAlba1 from Trypanosoma brucei	19
JBP1 and JBP3 have conserved structures but different affinity to base-J	19
Dual pattern of cholesterol-induced decoupling of residue-residue interactions of Kir2.2	18
3D quantification of the lacunocanalicular network on human femoral diaphysis through synchrotron radiation-based nanoCT	17
2.85 and 2.99 Å resolution structures of 110 kDa nitrite reductase determined by 200 kV cryogenic electron microscopy	16
Outside Front Cover	16
Focused classifications and refinements in high-resolution single particle cryo-EM analysis	16
Structure and heterogeneity of a highly cargo-loaded encapsulin shell	16
Structural modeling of two plant UDP-dependent sugar-sugar glycosyltransferases reveals a conserved glutamic acid residue that is a hallmark for sugar acceptor recognition	16
Metallic support films reduce optical heating in cryogenic correlative light and electron tomography	16
ArtiaX: geometric models, camera paths and image processing tools	16
Crystal structure of the Escherichia coli CusS kinase core	16
Outside Front Cover	16
Cryo-EM structure of a eukaryotic zinc transporter at a low pH suggests its Zn2+-releasing mechanism	15
Local defocus estimation in single particle analysis in cryo-electron microscopy	15
New insight on spatial localization and microstructures of calcite-aragonite interfaces in adult shell of Haliotis tuberculata: Investigations of wild and farmed abalones by FTIR and Raman mapping	15
Domain crossover in the reductase subunit of NADPH-dependent assimilatory sulfite reductase	15
Outside Front Cover	15
Structural and dynamic insights into the HNH nuclease of divergent Cas9 species	15
Automated picking of amyloid fibrils from cryo-EM images for helical reconstruction with RELION	15
A RhoA structure with switch II flipped outward revealed the conformational dynamics of switch II region	15
Common structural features in some of the sequentially distant neurotransmitter transporters N-termini	14
Daisy: An integrated repeat protein curation service	14
Identification of structural determinants of nicotinamide phosphoribosyl transferase (NAMPT) activity and substrate selectivity	13
Three dimensional structures of the inner and outer pig petrous bone using FIB-SEM: Implications for development and ancient DNA preservation	13
EMDA: A Python package for Electron Microscopy Data Analysis	13
Structural analysis of the water channel AQP2 by single-particle cryo-EM	12
Outside Front Cover	12
Crystal structure of breast regression protein 39 (BRP39), a signaling glycoprotein expressed during mammary gland apoptosis, at 2.6 Å resolution	12
Outside Front Cover	12
Biochemical, structural and dynamical studies reveal strong differences in the thermal-dependent allosteric behavior of two extremophilic lactate dehydrogenases	12
Cell recognition based on atomic force microscopy and modified residual neural network	12
Bacterial NadQ (COG4111) is a Nudix-like, ATP-responsive regulator of NAD biosynthesis	11
Assessment of scoring functions to rank the quality of 3D subtomogram clusters from cryo-electron tomography	11
Deletion within ameloblastin multitargeting domain reduces its interaction with artificial cell membrane	11
Structure and conformational variability of the HER2-trastuzumab-pertuzumab complex	10
Structural analysis of the human C5a-C5aR1 complex using cryo-electron microscopy	10
2.0 Å cryo-EM structure of the 55 kDa nucleoplasmin domain of AtFKBP53	10
A glimpse into the hidden world of the flexible C-terminal protein binding domains of human RAD52	10
DeepQs: Local quality assessment of cryo-EM density map by deep learning map-model fit score	10
Molecular insights into the binding interactions and energetics of the omicron spike variant with hACE2 and a neutralizing antibody	10
Genetic basis of stony coral biomineralization: History, trends and future prospects	10
Integrating on-grid immunogold labeling and cryo-electron tomography to reveal photosystem II structure and spatial distribution in thylakoid membranes	10
Tooth acellular extrinsic fibre cementum incremental lines in humans are formed by parallel branched Sharpey’s fibres and not by its mineral phase	10
Outside Front Cover	9

MEPSi: A tool for simulating tomograms of membrane-embedded proteins	9
Editorial Board	9
Opportunities for biomineralization research using multiscale computed X-ray tomography as exemplified by bone imaging	9
Journal of Structural Biology – Paper of the Year 2022	9
Improving CryoEM maps of symmetry-mismatched macromolecular assemblies: A case study on the flagellar motor	9
Structural insights into ring-building motif domains involved in bacterial sporulation	9
Outside Front Cover	9
Calcite crystal orientation patterns in the bilayers of laminated shells of benthic rotaliid foraminifera	9
Structural insights into the engagement of lysophosphatidic acid receptor 1 with different G proteins	9
Structural basis of O-methylation of (2-heptyl-)1-hydroxyquinolin-4(1H)-one and related compounds by the heterocyclic toxin methyltransferase Rv0560c of Mycobacterium tuberculosis	9
The crystal structure of yeast regulatory subunit reveals key evolutionary insights into Protein Kinase A oligomerization	8
NMR structure and dynamics of Q4DY78, a conserved kinetoplasid-specific protein from Trypanosoma cruzi	8
Mitoxantrone stacking does not define the active or inactive state of USP15 catalytic domain	8
A set of common movements within GPCR-G-protein complexes from variability analysis of cryo-EM datasets	8
Potential implications of the glycosylation patterns in collagen α1(I) and α2(I) chains for fibril assembly and growth	8
Dense intracellular ion pools in unicellular organisms	8
Desmosomal protein structure and function and the impact of disease-causing mutations	7
A key piece of the puzzle: The central tetramer of the Saccharomyces cerevisiae septin protofilament and its implications for self-assembly	7
Characterization of heterogeneity in nanodisc samples using Feret signatures	7
Evolution and biomineralization of pteropod shells	7
Identification and demonstration of roGFP2 as an environmental sensor for cryogenic correlative light and electron microscopy	7
Direct control of shell regeneration by the mantle tissue in the pearl oyster Pinctada fucata	7
Biochemical, structural and dynamical characterizations of the lactate dehydrogenase from Selenomonas ruminantium provide information about an intermediate evolutionary step prior to complete alloster	7
Sub-micrometric spatial distribution of amorphous and crystalline carbonates in biogenic crystals using coherent Raman microscopy	7
Elucidation of critical pH-dependent structural changes in Botulinum Neurotoxin E	7
Cryo-EM structure of AMP-PNP-bound human mitochondrial ATP-binding cassette transporter ABCB7	7
Effects of Xylanase A double mutation on substrate specificity and structural dynamics	7
Crystal structures of the fatty acid biosynthesis initiation enzymes in Bacillus subtilis	7
Mean curvature motion facilitates the segmentation and surface visualization of electron tomograms	7
The role of tandem repeats in bacterial functional amyloids	7
Morphological and genetic mechanisms underlying the plasticity of the coral Porites astreoides across depths in Bermuda	7
Conformational landscape of the mycobacterial inosine 5′-monophosphate dehydrogenase octamerization interface	7
Shark centra microanatomy and mineral density variation studied with laboratory microComputed Tomography	7
Computational structural biology: Evolution of the field	7
The crystal structure of the H116Q mutant of NDM-1: An enzyme devoid of zinc ions	7
3D distribution of biomineral and chitin matrix in the stomatopod dactyl club by high energy XRD-CT	7
Structure determination and analysis of titin A-band fibronectin type III domains provides insights for disease-linked variants and protein oligomerisation	6
NUDIM: A non-uniform fast Fourier transform based dual-space constraint iterative reconstruction method in biological electron tomography	6
A disulfide-stabilised helical hairpin fold in acrorhagin I: An emerging structural motif in peptide toxins	6
Statistical proofs of the interdependence between nearest neighbor effects on polypeptide backbone conformations	6
Determinants of site-selectivity in human ileal bile acid-binding protein by NMR dynamic analysis of a functionally-impaired mutant	6
A new algorithm for particle weighted subtraction to decrease signals from unwanted components in single particle analysis	6
Structure and self-association of Arrestin-1	6
Identification and evaluation of potential inhibitor molecules against TcyA from Candidatus Liberibacter asiaticus	6
Structural basis for the effects of Ser387 phosphorylation of MgcRacGAP on its GTPase-activating activities for CDC42 and RHOA	6
Cryo-EM structure of bacterial nitrilase reveals insight into oligomerization, substrate recognition, and catalysis	6
Cryo-EM structure of the cetacean morbillivirus nucleoprotein-RNA complex	6
NMR and semi-synthesis in synergy to study protein regulation	6
Editorial Board	6
Towards in situ high-resolution imaging of viruses and macromolecular complexes using cryo-electron tomography	6
Quantitative 3D electron microscopy characterization of mitochondrial structure, mitophagy, and organelle interactions in murine atrial fibrillation	6
Cryo-Electron Microscopy: The field of 1,000+ methods	6
Transcriptional activity and splicing factors are preserved during physiological apoptosis	6
Prokaryotic membrane coat - like proteins: An update	6
A non-parametric approach to particle picking in all frames	6
Classification of helical polymers with deep-learning language models	6
Phylogenetic analysis and homology modelling of a new Cry8A crystal protein expressed in a sporulating soil bacterium	6
The intricacies of tooth enamel: Embryonic origin, development and human genetics	6
Editorial Board	6
Journal of Structural Biology – Paper of the Year 2021	6
Insight into structural biophysics from solution X-ray scattering	6
Kinetic and structural studies of gamma-carbonic anhydrase from the oral pathogen Porphyromonas gingivalis	5
Matrix/mineral ratio and domain size variation with bone tissue age: A photothermal infrared study	5
Journal of Structural Biology – Paper of the Year 2021	5
High-throughput segmentation, data visualization, and analysis of sea star skeletal networks	5
Practical considerations for using K3 cameras in CDS mode for high-resolution and high-throughput single particle cryo-EM	5
Anti-NSCLC activity in vitro of Hsp90N inhibitor KW-2478 and complex crystal structure determination of Hsp90N-KW-2478	5
RosettaHDX: Predicting antibody-antigen interaction from hydrogen-deuterium exchange mass spectrometry data	5
Porous assembly of an antifungal protein mediated by zinc and sulfonato-calix[8]arene	5
Computational Engineering of siderocalin to modulate its binding affinity to the antihypertension drug candesartan	5
Sumoylation and the oncogenic E17K mutation affect AKT1 subcellular distribution and impact on Nanog-binding dynamics to chromatin in embryonic stem cells	5
GCTransNet: 3D mitochondrial instance segmentation based on Global Context Vision Transformers	5
SAM1 domain of SASH1 harbors distinctive structural heterogeneity	5
Unveiling success determinants for AMB-assisted phase expansion of fusion proteins in ARP/wARP	5
A generalist deep-learning volume segmentation tool for volume electron microscopy of biological samples	5
CryoSamba: Self-supervised deep volumetric denoising for cryo-electron tomography data	5
Epitope-Analyzer: A structure-based webtool to analyze broadly neutralizing epitopes	5
The SIRAH force field: A suite for simulations of complex biological systems at the coarse-grained and multiscale levels	5
Three-dimensional reconstruction of Magnetofaba australis strain IT-1: Magnetosome chain position with respect to flagella	5
Single particle cryo-EM analysis of Rickettsia conorii Sca2 reveals a formin-like core	5

Exploring the folding landscape of leptin: Insights into threading pathways	5
Outside Front Cover	5
Selective signal enhancement in Fourier space as a tool for discovering ultrastructural organization of macromolecules from in situ TEM	4
Structural insight to elucidate the binding specificity of the anti-cortisol Fab fragment with glucocorticoids	4
Outside Front Cover	4
Structure guided mutagenesis reveals the substrate determinants of guanine deaminase	4
Solid-state NMR MAS CryoProbe enables structural studies of human blood protein vitronectin bound to hydroxyapatite	4
Cryo-EM density maps adjustment for subtraction, consensus and sharpening	4
Editorial Board	4
Crystal structure of the potato leafroll virus coat protein and implications for viral assembly	4
Revisiting the Ramachandran plot based on statistical analysis of static and dynamic characteristics of protein structures	4
Exploring α-synuclein stability under the external electrostatic field: Effect of repeat unit	4
Editorial Board	4
Four-dimensional microED of conformational dynamics in protein microcrystals on the femto-to-microsecond timescales	4
Outlier removal in cryo-EM via radial profiles	4
Recent advances in the application of atomic force microscopy to structural biology	4
A review of the approaches used to solve sub-100 kDa membrane proteins by cryo-electron microscopy	4
Three-dimensional cellular architecture of the sigmoid filament in Trichomonas vaginalis	4
Comparison of the global crystallographic texture of minerals in the shells of Bathymodiolus thermophilus Kenk et B.R. Wilson, 1985 and species of the genus Mytilus Linnaeus, 1758	4
Outside Front Cover	4
Lack of embryonic skeletal muscle in mice leads to abnormal mineral deposition and growth	4
Electron-counting MicroED data with the K2 and K3 direct electron detectors	4
New insights into the effect of mutations on affibody-Fc interaction, a molecular dynamics simulation approach	4
Phylogeny and structural peculiarities of the EB proteins of diatoms	3
Cryo-EM image alignment: From pair-wise to joint with deep unsupervised difference learning	3
A 3D-printed flow-cell for on-grid purification of electron microscopy samples directly from lysate	3
A strained N-capping motif in α-helices of βαβ-units	3
Investigating the role of elastin and extracellular matrix damage in cardiovascular calcification	3
Robust ab initio solution of the cryo-EM reconstruction problem at low resolution with small data sets	3
Integration of software tools for integrative modeling of biomolecular systems	3
The structure of exopolyphosphatase (PPX) from Porphyromonas gingivalis in complex with substrate analogs and magnesium ions reveals the basis for polyphosphate processivity	3
Structural and biophysical characterization of PadR family protein Rv0047c of Mycobacterium tuberculosis H37Rv	3
Ice thickness control and measurement in the VitroJet for time-efficient single particle structure determination	3
Increased cochlear otic capsule thickness and intracortical canal porosity in the oim mouse model of osteogenesis imperfecta	3
Optimal 3D angular sampling with applications to cryo-EM problems	3
Characterization of the growth plate-bone interphase region using cryo-FIB SEM 3D volume imaging	3
Biological applications of the scanning transmission electron microscope	3
A STRP-ed definition of Structured Tandem Repeats in Proteins	3
A computational approach to predict the effects of missense mutations on protein amyloidogenicity: A case study in hereditary transthyretin cardiomyopathy	3
Characterization of conformational flexibility in protein structures by applying artificial intelligence to molecular modeling	3
Insights into the dynamic interactions at chemokine-receptor interfaces and mechanistic models of chemokine binding	3
Calmodulin binds to the STAS domain of SLC26A5 prestin with a calcium-dependent, one-lobe, binding mode	3
Rapid tool for cell nanoarchitecture integrity assessment	3
The repetitive structure of DNA clamps: An overlooked protein tandem repeat	3
Crystal structure of the pheromone Er-13 from the ciliate Euplotes raikovi, with implications for a protein–protein association model in pheromone/receptor interactions	3
Correlative transmission electron microscopy and high-resolution hard X-ray fluorescence microscopy of cell sections to measure trace element concentrations at the organelle level	3
Different strategies towards strength: Unveiling the role of Zn vs Mn/Ca and chitin arrangement in scorpion stingers	3
Chemically cross-linked hydrogels from repetitive protein arrays	3
Visualizing transiently associated catalytic domains in assembly-line biosynthesis using cryo-electron microscopy	3
Why does the first protein repeat often become the only one?	3
OpenFIBSEM: A universal API for FIBSEM control	3
Crystal structure of the GluK1 ligand-binding domain with kainate and the full-spanning positive allosteric modulator BPAM538	2
Structure basis of two nanobodies neutralizing SARS-CoV-2 Omicron variant by targeting ultra-conservative epitopes	2
A feature-guided, focused 3D signal permutation method for subtomogram averaging	2
Crystal structure of the anti-CRISPR repressor Aca2	2
The role of propeptide-mediated autoinhibition and intermolecular chaperone in the maturation of cognate catalytic domain in leucine aminopeptidase	2
Phylogenetic analysis and structural studies of heteromeric acetyl-CoA carboxylase from the oleaginous Amazonian microalgae Ankistrodesmus sp.: Insights into the BC and BCCP subunits	2
Engineering of brick and staple components for ordered assembly of synthetic repeat proteins	2
Structural organization of the organic sheath that delineates extracellular seta silicification in diatoms	2
Effects of Gα C-terminal deletion on the intrinsic GDP release/GTPase activity and conformational dynamics	2
Outside Front Cover	2
Structural principles of CRISPR-Cas enzymes used in nucleic acid detection	2
Off-axis electron holography of unstained bacteriophages: Towards electrostatic potential measurement of biological samples	2
Montage electron tomography of vitrified specimens	2
DeepAlign, a 3D alignment method based on regionalized deep learning for Cryo-EM	2
Perspective: Emerging strategies for determining atomic-resolution structures of macromolecular complexes within cells	2
Disulfide bonds enhance thermal stability and thumb region drives activity of the glycoside hydrolase 11 xylanase rMxylcd	2
Cage versus sheet: Probing the Determinants of Protein – Cucurbit[7]uril Crystalline Architectures	2
Characterization of SARS-CoV-2 nucleocapsid protein oligomers	2
An inducible model for medial calcification based on matrix Gla protein deficiency	2
Dengue virus-host interactions: Structural and mechanistic insights for future therapeutic strategies	2
Structural and biochemical basis for the substrate specificity of Pad-1, an indole-3-pyruvic acid aminotransferase in auxin homeostasis	2
Lattice micropatterning for cryo-electron tomography studies of cell-cell contacts	2
Gold nanomaterials and their potential use as cryo-electron tomography labels	2
Smart data collection for CryoEM	2
Deep generative modeling for volume reconstruction in cryo-electron microscopy	2