Journal of Structural Biology

Article	Citations
Calcium carbonate deposition in the spicules of the sponge Heteropia glomerosa (Porifera, Calcarea)	49
Allosteric inhibition of cytosolic NADP+-dependent isocitrate dehydrogenase by oxaloacetate	47
Disorder-to-order transition of Synaptobrevin-2: Tracing the conformational diversity of a synaptic SNARE protein	45
Exploring high-resolution cryo-ET and subtomogram averaging capabilities of contemporary DEDs	42
Characterization of NMDA receptor Allostery modulation	41
Dual-colour super-resolution cryoCLEM in mammalian cells using the fluorescent proteins rsTagRFP and rsEGFP2	38
Deep Learning-based structure modelling illuminates structure and function in uncharted regions of β-solenoid fold space	37
Tropomyosin induces the synthesis of magnesian calcite in sea urchin spines	33
Inter-Domain interactions Slow BoNT/A’s onset of action	32
ContinuousFlex: Software package for analyzing continuous conformational variability of macromolecules in cryo electron microscopy and tomography data	31
Multishot tomography for high-resolution in situ subtomogram averaging	31
Locating cellular contents during cryoFIB milling using cellular secondary-electron imaging	26
Outside Front Cover	24
High-resolution single-particle imaging at 100–200 keV with the Gatan Alpine direct electron detector	23
Outside Front Cover	23
Studying protein–protein interactions: Latest and most popular approaches	23
Interaction of berberine with different forms of DNA in human telomeric region	22
Focused ion beam-SEM 3D study of osteodentin in the teeth of the Atlantic wolfish Anarhichas lupus	21
Isolation and reconstruction of cardiac mitochondria from SBEM images using a deep learning-based method	20
Transcriptome profiling of DPP stimulated DPSCs identifies the role of autophagy in odontogenic differentiation	20
Changes in Arabidopsis thaliana seedling cell wall assembly induced by treatment with Yariv reagent – Molecular features & visualization with immunocytochemistry and a fluorescent Yariv reagent	20
JBP1 and JBP3 have conserved structures but different affinity to base-J	20
Outside Front Cover	20
Comprehensive structural overview of the C-terminal ligand-binding domains of the TetR family regulators	20
Dual pattern of cholesterol-induced decoupling of residue-residue interactions of Kir2.2	19

Insights into the pathogenic mechanisms associated with the SARS-CoV-2 spike protein	18
ArtiaX: geometric models, camera paths and image processing tools	17
Editorial Board	17
G-Quadruplex structures within the hfq gene regulate RNA–protein interactions in Acinetobacter baumannii	17
3D quantification of the lacunocanalicular network on human femoral diaphysis through synchrotron radiation-based nanoCT	16
Structural and kinetic analysis of the monofunctional Staphylococcus aureus PBP1	16
Structure and heterogeneity of a highly cargo-loaded encapsulin shell	16
Outside Front Cover	16
Focused classifications and refinements in high-resolution single particle cryo-EM analysis	15
Domain crossover in the reductase subunit of NADPH-dependent assimilatory sulfite reductase	15
Structural and dynamic insights into the HNH nuclease of divergent Cas9 species	15
Nickel-NTA lipid-monolayer affinity grids allow for high-resolution structure determination by cryo-EM	14
Metallic support films reduce optical heating in cryogenic correlative light and electron tomography	14
Crystal structure of the Escherichia coli CusS kinase core	14
A RhoA structure with switch II flipped outward revealed the conformational dynamics of switch II region	13
Cryo-EM structure of a eukaryotic zinc transporter at a low pH suggests its Zn2+-releasing mechanism	13
New insight on spatial localization and microstructures of calcite-aragonite interfaces in adult shell of Haliotis tuberculata: Investigations of wild and farmed abalones by FTIR and Raman mapping	13
Identification of structural determinants of nicotinamide phosphoribosyl transferase (NAMPT) activity and substrate selectivity	12
Preferential binding as a driving mechanism of lipid domains formation	12
Local microenvironments of capsomer variants in the PBCV-1	11
Daisy: An integrated repeat protein curation service	11
Three dimensional structures of the inner and outer pig petrous bone using FIB-SEM: Implications for development and ancient DNA preservation	11
Local defocus estimation in single particle analysis in cryo-electron microscopy	11
Outside Front Cover	11
EMDA: A Python package for Electron Microscopy Data Analysis	10
Molecular insights into the binding interactions and energetics of the omicron spike variant with hACE2 and a neutralizing antibody	10
A glimpse into the hidden world of the flexible C-terminal protein binding domains of human RAD52	10
Common structural features in some of the sequentially distant neurotransmitter transporters N-termini	10
Deletion within ameloblastin multitargeting domain reduces its interaction with artificial cell membrane	10
Opportunities for biomineralization research using multiscale computed X-ray tomography as exemplified by bone imaging	10
Outside Front Cover	10
Tooth acellular extrinsic fibre cementum incremental lines in humans are formed by parallel branched Sharpey’s fibres and not by its mineral phase	10
Structural analysis of the water channel AQP2 by single-particle cryo-EM	10
Cell recognition based on atomic force microscopy and modified residual neural network	9
Structural analysis of the human C5a-C5aR1 complex using cryo-electron microscopy	9
DeepQs: Local quality assessment of cryo-EM density map by deep learning map-model fit score	9
Bacterial NadQ (COG4111) is a Nudix-like, ATP-responsive regulator of NAD biosynthesis	9
2.0 Å cryo-EM structure of the 55 kDa nucleoplasmin domain of AtFKBP53	9
Structural insights into the engagement of lysophosphatidic acid receptor 1 with different G proteins	9
Outside Front Cover	9
Cholesterol crystals in reservosomes of Trypanosoma cruzi	9
Structure and conformational variability of the HER2-trastuzumab-pertuzumab complex	9
Sub-micrometric spatial distribution of amorphous and crystalline carbonates in biogenic crystals using coherent Raman microscopy	8
Outside Front Cover	8
Morphological and genetic mechanisms underlying the plasticity of the coral Porites astreoides across depths in Bermuda	8
Cryo-EM structure of AMP-PNP-bound human mitochondrial ATP-binding cassette transporter ABCB7	8
Editorial Board	8
Outside Front Cover	8
Structural insights into ring-building motif domains involved in bacterial sporulation	8
MEPSi: A tool for simulating tomograms of membrane-embedded proteins	8

Journal of Structural Biology – Paper of the Year 2022	8
Outside Front Cover	8
Conformational landscape of the mycobacterial inosine 5′-monophosphate dehydrogenase octamerization interface	8
Potential implications of the glycosylation patterns in collagen α1(I) and α2(I) chains for fibril assembly and growth	8
Crystal structures of the fatty acid biosynthesis initiation enzymes in Bacillus subtilis	7
Shark centra microanatomy and mineral density variation studied with laboratory microComputed Tomography	7
Announcement: Journal of Structural Biology: Paper of the year	7
Improving CryoEM maps of symmetry-mismatched macromolecular assemblies: A case study on the flagellar motor	7
Direct control of shell regeneration by the mantle tissue in the pearl oyster Pinctada fucata	7
Effects of Xylanase A double mutation on substrate specificity and structural dynamics	7
The role of tandem repeats in bacterial functional amyloids	7
Identification and demonstration of roGFP2 as an environmental sensor for cryogenic correlative light and electron microscopy	7
3D distribution of biomineral and chitin matrix in the stomatopod dactyl club by high energy XRD-CT	7
Characterization of heterogeneity in nanodisc samples using Feret signatures	7
The crystal structure of the H116Q mutant of NDM-1: An enzyme devoid of zinc ions	7
Mean curvature motion facilitates the segmentation and surface visualization of electron tomograms	7
A key piece of the puzzle: The central tetramer of the Saccharomyces cerevisiae septin protofilament and its implications for self-assembly	7
Computational structural biology: Evolution of the field	7
Mitoxantrone stacking does not define the active or inactive state of USP15 catalytic domain	7
Sequence/structural/functional relationships between Ganoderma fungal immunomodulatory proteins (gFIPs) and proteins involved in the modulation of immune response	7
Elucidation of critical pH-dependent structural changes in Botulinum Neurotoxin E	7
Insight into structural biophysics from solution X-ray scattering	6
Editorial Board	6
A non-parametric approach to particle picking in all frames	6
Transcriptional activity and splicing factors are preserved during physiological apoptosis	6
Computational Engineering of siderocalin to modulate its binding affinity to the antihypertension drug candesartan	6
Membrane and vesicle structure detection in cryo-electron tomography based on deep learning	6
Quantitative 3D electron microscopy characterization of mitochondrial structure, mitophagy, and organelle interactions in murine atrial fibrillation	6
Cryo-Electron Microscopy: The field of 1,000+ methods	6
Structural basis for the effects of Ser387 phosphorylation of MgcRacGAP on its GTPase-activating activities for CDC42 and RHOA	6
Phylogenetic analysis and homology modelling of a new Cry8A crystal protein expressed in a sporulating soil bacterium	6
Prokaryotic membrane coat - like proteins: An update	6
Editorial Board	6
Journal of Structural Biology – Paper of the Year 2021	6
The intricacies of tooth enamel: Embryonic origin, development and human genetics	6
Identification and evaluation of potential inhibitor molecules against TcyA from Candidatus Liberibacter asiaticus	6
Biochemical, structural and dynamical characterizations of the lactate dehydrogenase from Selenomonas ruminantium provide information about an intermediate evolutionary step prior to complete alloster	6
Towards in situ high-resolution imaging of viruses and macromolecular complexes using cryo-electron tomography	6
Cryo-EM structure of bacterial nitrilase reveals insight into oligomerization, substrate recognition, and catalysis	6
Classification of helical polymers with deep-learning language models	6
Determinants of site-selectivity in human ileal bile acid-binding protein by NMR dynamic analysis of a functionally-impaired mutant	6
A new algorithm for particle weighted subtraction to decrease signals from unwanted components in single particle analysis	6
Structure and self-association of Arrestin-1	6
Epitope-Analyzer: A structure-based webtool to analyze broadly neutralizing epitopes	5
Statistical proofs of the interdependence between nearest neighbor effects on polypeptide backbone conformations	5
CryoSamba: Self-supervised deep volumetric denoising for cryo-electron tomography data	5
A generalist deep-learning volume segmentation tool for volume electron microscopy of biological samples	5
Single particle cryo-EM analysis of Rickettsia conorii Sca2 reveals a formin-like core	5
Matrix/mineral ratio and domain size variation with bone tissue age: A photothermal infrared study	5
Structure determination and analysis of titin A-band fibronectin type III domains provides insights for disease-linked variants and protein oligomerisation	5
Kinetic and structural studies of gamma-carbonic anhydrase from the oral pathogen Porphyromonas gingivalis	5
Unveiling success determinants for AMB-assisted phase expansion of fusion proteins in ARP/wARP	5
Sumoylation and the oncogenic E17K mutation affect AKT1 subcellular distribution and impact on Nanog-binding dynamics to chromatin in embryonic stem cells	5
The SIRAH force field: A suite for simulations of complex biological systems at the coarse-grained and multiscale levels	5
NMR and semi-synthesis in synergy to study protein regulation	5
RosettaHDX: Predicting antibody-antigen interaction from hydrogen-deuterium exchange mass spectrometry data	5
Journal of Structural Biology – Paper of the Year 2021	5
Comparison of the global crystallographic texture of minerals in the shells of Bathymodiolus thermophilus Kenk et B.R. Wilson, 1985 and species of the genus Mytilus Linnaeus, 1758	4
Outlier removal in cryo-EM via radial profiles	4
Prediction of a structural change in the orientation of the cytoplasmic signaling unit of human Toll-like receptor 9 upon binding of agonistic and antagonistic DNA molecules	4
Editorial Board	4
Structural insight to elucidate the binding specificity of the anti-cortisol Fab fragment with glucocorticoids	4
SAM1 domain of SASH1 harbors distinctive structural heterogeneity	4
CDP-alcohol phosphotransferases: Structures and function of highly diverse sub-classes within a protein family	4
Revisiting the Ramachandran plot based on statistical analysis of static and dynamic characteristics of protein structures	4
Four-dimensional microED of conformational dynamics in protein microcrystals on the femto-to-microsecond timescales	4
New insights into the effect of mutations on affibody-Fc interaction, a molecular dynamics simulation approach	4
Outside Front Cover	4
A review of the approaches used to solve sub-100 kDa membrane proteins by cryo-electron microscopy	4
Recent advances in the application of atomic force microscopy to structural biology	4
Crystal structure of the potato leafroll virus coat protein and implications for viral assembly	4
GCTransNet: 3D mitochondrial instance segmentation based on Global Context Vision Transformers	4
Three-dimensional reconstruction of Magnetofaba australis strain IT-1: Magnetosome chain position with respect to flagella	4
Selective signal enhancement in Fourier space as a tool for discovering ultrastructural organization of macromolecules from in situ TEM	4
Announcement: Journal of Structural Biology: Paper of the year	4
Editorial Board	4
Lack of embryonic skeletal muscle in mice leads to abnormal mineral deposition and growth	4
Exploring α-synuclein stability under the external electrostatic field: Effect of repeat unit	4
Three-dimensional cellular architecture of the sigmoid filament in Trichomonas vaginalis	4
High-throughput segmentation, data visualization, and analysis of sea star skeletal networks	4

Exploring the folding landscape of leptin: Insights into threading pathways	4
Why does the first protein repeat often become the only one?	3
Solid-state NMR MAS CryoProbe enables structural studies of human blood protein vitronectin bound to hydroxyapatite	3
Structural and biophysical characterization of PadR family protein Rv0047c of Mycobacterium tuberculosis H37Rv	3
Insights into the dynamic interactions at chemokine-receptor interfaces and mechanistic models of chemokine binding	3
Optimal 3D angular sampling with applications to cryo-EM problems	3
The repetitive structure of DNA clamps: An overlooked protein tandem repeat	3
Hurdles and advancements in experimental membrane protein structural biology	3
Precise ligand-selective mechanism at the fab domain of a tau-recognizing antibody	3
Electron-counting MicroED data with the K2 and K3 direct electron detectors	3
Characterization of conformational flexibility in protein structures by applying artificial intelligence to molecular modeling	3
Ice thickness control and measurement in the VitroJet for time-efficient single particle structure determination	3
Different strategies towards strength: Unveiling the role of Zn vs Mn/Ca and chitin arrangement in scorpion stingers	3
Chemically cross-linked hydrogels from repetitive protein arrays	3
OpenFIBSEM: A universal API for FIBSEM control	3
Binding of an N protein peptide to M protein of a bat coronavirus	3
Cryo-EM image alignment: From pair-wise to joint with deep unsupervised difference learning	3
A computational approach to predict the effects of missense mutations on protein amyloidogenicity: A case study in hereditary transthyretin cardiomyopathy	3
A STRP-ed definition of Structured Tandem Repeats in Proteins	3
Crystal structure of the pheromone Er-13 from the ciliate Euplotes raikovi, with implications for a protein–protein association model in pheromone/receptor interactions	3
Deep geometric framework to predict antibody–antigen binding affinity	2
Perspective: Emerging strategies for determining atomic-resolution structures of macromolecular complexes within cells	2
Phylogenetic analysis and structural studies of heteromeric acetyl-CoA carboxylase from the oleaginous Amazonian microalgae Ankistrodesmus sp.: Insights into the BC and BCCP subunits	2
Deep generative modeling for volume reconstruction in cryo-electron microscopy	2
Structural organization of the organic sheath that delineates extracellular seta silicification in diatoms	2
A 3D-printed flow-cell for on-grid purification of electron microscopy samples directly from lysate	2
A strained N-capping motif in α-helices of βαβ-units	2
Integration of software tools for integrative modeling of biomolecular systems	2
An inducible model for medial calcification based on matrix Gla protein deficiency	2
The crystal structure of Mycobacterium thermoresistibile MurE ligase reveals the binding mode of the substrate m-diaminopimelate	2
Gold nanomaterials and their potential use as cryo-electron tomography labels	2
Engineering of brick and staple components for ordered assembly of synthetic repeat proteins	2
Cage versus sheet: Probing the Determinants of Protein – Cucurbit[7]uril Crystalline Architectures	2
Crystal structure of the GluK1 ligand-binding domain with kainate and the full-spanning positive allosteric modulator BPAM538	2
Off-axis electron holography of unstained bacteriophages: Towards electrostatic potential measurement of biological samples	2
Structural principles of CRISPR-Cas enzymes used in nucleic acid detection	2
A feature-guided, focused 3D signal permutation method for subtomogram averaging	2
Investigating the role of elastin and extracellular matrix damage in cardiovascular calcification	2
Characterization of SARS-CoV-2 nucleocapsid protein oligomers	2
Montage electron tomography of vitrified specimens	2
Structural and biochemical basis for the substrate specificity of Pad-1, an indole-3-pyruvic acid aminotransferase in auxin homeostasis	2
Multimodal analysis and comparison of stoichiometric and structural characteristics of parosteal and conventional osteosarcoma with massive sclerosis in human bone	2
Smart data collection for CryoEM	2
Outside Front Cover	2
Disulfide bonds enhance thermal stability and thumb region drives activity of the glycoside hydrolase 11 xylanase rMxylcd	2
Effects of Gα C-terminal deletion on the intrinsic GDP release/GTPase activity and conformational dynamics	2
Structure basis of two nanobodies neutralizing SARS-CoV-2 Omicron variant by targeting ultra-conservative epitopes	2
Robust ab initio solution of the cryo-EM reconstruction problem at low resolution with small data sets	2
Biological applications of the scanning transmission electron microscope	2
Dengue virus-host interactions: Structural and mechanistic insights for future therapeutic strategies	2
Outside Front Cover	2