Journal of Structural Biology

Article	Citations
Obituary Luis Bachmann	733
Introduction to the special issue on the 14th International conference on the chemistry and biology of mineralized tissues	81
Correlative Raman spectroscopy and electron microscopy identifies glycogen rich deposits correlated with local structural defects in long bones of type IV osteogenesis imperfecta patients	50
Structural basis for the effects of Ser387 phosphorylation of MgcRacGAP on its GTPase-activating activities for CDC42 and RHOA	33
Vesicle Picker: A tool for efficient identification of membrane protein complexes in vesicles	32
Journal of Structural Biology – Paper of the Year 2020	32
Editorial Board	30
The CryoEM structure of human serum albumin in complex with ligands	29
Structural analysis of the human C5a-C5aR1 complex using cryo-electron microscopy	29
Cell recognition based on atomic force microscopy and modified residual neural network	27
A large disordered region confers a wide spanning volume to vertebrate Suppressor of Fused as shown in a trans-species solution study	27
Editorial Board	27
Robust ab initio solution of the cryo-EM reconstruction problem at low resolution with small data sets	27
Disorder-to-order transition of Synaptobrevin-2: Tracing the conformational diversity of a synaptic SNARE protein	26
Molecular insights into the binding interactions and energetics of the omicron spike variant with hACE2 and a neutralizing antibody	23
Biochemical, structural and dynamical studies reveal strong differences in the thermal-dependent allosteric behavior of two extremophilic lactate dehydrogenases	23
Editorial Board	23
Biological applications of the scanning transmission electron microscope	22
Outside Front Cover	22
Structural organization of xanthine crystals in the median ocellus of a member of the ancestral insect group Archaeognatha	22
Beyond the surface: Investigation of tumorsphere morphology using volume electron microscopy	21
Integration of software tools for integrative modeling of biomolecular systems	21
NUDIM: A non-uniform fast Fourier transform based dual-space constraint iterative reconstruction method in biological electron tomography	20
Correlative transmission electron microscopy and high-resolution hard X-ray fluorescence microscopy of cell sections to measure trace element concentrations at the organelle level	20
Determination of amino acids that favour the αL region using Ramachandran propensity plots. Implications for α-sheet as the possible amyloid intermediate	20

Outside Front Cover	19
Crystal structure of breast regression protein 39 (BRP39), a signaling glycoprotein expressed during mammary gland apoptosis, at 2.6 Å resolution	19
Comparative structural, biophysical, and receptor binding study of true type and wild type AAV2	17
Outside Front Cover	17
A disulfide-stabilised helical hairpin fold in acrorhagin I: An emerging structural motif in peptide toxins	17
Transcriptional activity and splicing factors are preserved during physiological apoptosis	16
ScipionTomo: Towards cryo-electron tomography software integration, reproducibility, and validation	16
Chemically cross-linked hydrogels from repetitive protein arrays	16
Crystal structure of chloroplast fructose-1,6-bisphosphate aldolase from the green alga Chlamydomonas reinhardtii	16
A STRP-ed definition of Structured Tandem Repeats in Proteins	15
ASOCEM: Automatic Segmentation Of Contaminations in cryo-EM	15
Classification of helical polymers with deep-learning language models	15
Amelogenesis: Transformation of a protein-mineral matrix into tooth enamel	15
Structural basis of O-methylation of (2-heptyl-)1-hydroxyquinolin-4(1H)-one and related compounds by the heterocyclic toxin methyltransferase Rv0560c of Mycobacterium tuberculosis	15
The structure of exopolyphosphatase (PPX) from Porphyromonas gingivalis in complex with substrate analogs and magnesium ions reveals the basis for polyphosphate processivity	15
Deep Learning-based structure modelling illuminates structure and function in uncharted regions of β-solenoid fold space	14
Cryo-EM reveals the structure and dynamics of a 723-residue malate synthase G	14
The repetitive structure of DNA clamps: An overlooked protein tandem repeat	14
Bacterial NadQ (COG4111) is a Nudix-like, ATP-responsive regulator of NAD biosynthesis	14
Assessment of scoring functions to rank the quality of 3D subtomogram clusters from cryo-electron tomography	14
Miffi: Improving the accuracy of CNN-based cryo-EM micrograph filtering with fine-tuning and Fourier space information	14
Opportunities for biomineralization research using multiscale computed X-ray tomography as exemplified by bone imaging	13
Deletion within ameloblastin multitargeting domain reduces its interaction with artificial cell membrane	13
Cryo-EM structure of the cetacean morbillivirus nucleoprotein-RNA complex	13
The structures of the C146A variant of the amidase from Pyrococcus horikoshii bound to glutaramide and acetamide suggest the basis of amide recognition	13
Integrating on-grid immunogold labeling and cryo-electron tomography to reveal photosystem II structure and spatial distribution in thylakoid membranes	12
Tropomyosin induces the synthesis of magnesian calcite in sea urchin spines	12
An exon-biased biophysical approach and NMR spectroscopy define the secondary structure of a conserved helical element within the HOTAIR long non-coding RNA	11
The structural biology of type III CRISPR-Cas systems	11
Tooth acellular extrinsic fibre cementum incremental lines in humans are formed by parallel branched Sharpey’s fibres and not by its mineral phase	11
Structure and conformational variability of the HER2-trastuzumab-pertuzumab complex	10
DeepQs: Local quality assessment of cryo-EM density map by deep learning map-model fit score	10
New protein families with hendecad coiled coils in the proteome of life	10
Genetic basis of stony coral biomineralization: History, trends and future prospects	10
Different strategies towards strength: Unveiling the role of Zn vs Mn/Ca and chitin arrangement in scorpion stingers	10
Structure of the cytoplasmic domain of SctV (SsaV) from the Salmonella SPI-2 injectisome and implications for a pH sensing mechanism	10
Rapid tool for cell nanoarchitecture integrity assessment	10
Investigating the role of elastin and extracellular matrix damage in cardiovascular calcification	10
A glimpse into the hidden world of the flexible C-terminal protein binding domains of human RAD52	10
Optimal 3D angular sampling with applications to cryo-EM problems	10
Keratin intermediate filament chains in the European common wall lizard (Podarcis muralis) and a potential keratin filament crosslinker	10
Modelling components of nacre structure in silico: Interactions of a nacre peptide with chitin and an aragonite surface	9
Lipid nanodiscs as a template for high-resolution cryo-EM structures of peripheral membrane proteins	9
Structural analysis of the water channel AQP2 by single-particle cryo-EM	9
A computational approach to predict the effects of missense mutations on protein amyloidogenicity: A case study in hereditary transthyretin cardiomyopathy	9
Spike protein fusion loop controls SARS-CoV-2 fusogenicity and infectivity	9
Cryo-EM structure of bacterial nitrilase reveals insight into oligomerization, substrate recognition, and catalysis	9
Phylogenetic analysis and homology modelling of a new Cry8A crystal protein expressed in a sporulating soil bacterium	9
Exploring high-resolution cryo-ET and subtomogram averaging capabilities of contemporary DEDs	9
Prokaryotic membrane coat - like proteins: An update	9

TAPASS: Tool for annotation of protein amyloidogenicity in the context of other structural states	8
Small-angle neutron scattering solution structures of NADPH-dependent sulfite reductase	8
Crystal structure of the pheromone Er-13 from the ciliate Euplotes raikovi, with implications for a protein–protein association model in pheromone/receptor interactions	8
Outside Front Cover	7
Kinetic and structural studies of gamma-carbonic anhydrase from the oral pathogen Porphyromonas gingivalis	7
Structural insights into ring-building motif domains involved in bacterial sporulation	7
Editorial Board	7
Editorial Board	7
Characterization of the growth plate-bone interphase region using cryo-FIB SEM 3D volume imaging	7
Inter-Domain interactions Slow BoNT/A’s onset of action	7
Computational Engineering of siderocalin to modulate its binding affinity to the antihypertension drug candesartan	7
A 3D-printed flow-cell for on-grid purification of electron microscopy samples directly from lysate	7
A strained N-capping motif in α-helices of βαβ-units	7
High-resolution structure of phosphoketolase from Bifidobacterium longum determined by cryo-EM single-particle analysis	7
Editorial Board	7
Structural insights into the engagement of lysophosphatidic acid receptor 1 with different G proteins	7
Statistical proofs of the interdependence between nearest neighbor effects on polypeptide backbone conformations	7
Journal of Structural Biology – Paper of the Year 2022	6
Matrix/mineral ratio and domain size variation with bone tissue age: A photothermal infrared study	6
Building alternative splicing and evolution-aware sequence-structure maps for protein repeats	6
Cryo-EM structure of AMP-PNP-bound human mitochondrial ATP-binding cassette transporter ABCB7	6
CryoEM single particle reconstruction with a complex-valued particle stack	6
NMR structure and dynamics of Q4DY78, a conserved kinetoplasid-specific protein from Trypanosoma cruzi	6
Cell-induced collagen alignment in a 3D in vitro culture during extracellular matrix production	6
Structural principles of CRISPR-Cas enzymes used in nucleic acid detection	6
TomoAlign: A novel approach to correcting sample motion and 3D CTF in CryoET	6
Outside Front Cover	6
Editorial Board	6
Structure basis of two nanobodies neutralizing SARS-CoV-2 Omicron variant by targeting ultra-conservative epitopes	6
The crystal structure of yeast regulatory subunit reveals key evolutionary insights into Protein Kinase A oligomerization	6
Super-resolution fluorescence imaging of cryosamples does not limit achievable resolution in cryoEM	6
MlaC belongs to a unique class of non-canonical substrate-binding proteins and follows a novel phospholipid-binding mechanism	6
Shark centra microanatomy and mineral density variation studied with laboratory microComputed Tomography	6
A feature-guided, focused 3D signal permutation method for subtomogram averaging	6
Epitope-Analyzer: A structure-based webtool to analyze broadly neutralizing epitopes	6
MEPSi: A tool for simulating tomograms of membrane-embedded proteins	6
Editorial Board	6
Multishot tomography for high-resolution in situ subtomogram averaging	6
Montage electron tomography of vitrified specimens	6
Multi-curve fitting and tubulin-lattice signal removal for structure determination of large microtubule-based motors	6
Proton irradiation induced reactive oxygen species promote morphological and functional changes in HepG2 cells	6
Lipid composition modulates interactions of p7 viroporin during membrane insertion	6
WITHDRAWN: NMR structure verifies the eponymous zinc finger domain of transcription factor ZNF750	6
Sumoylation and the oncogenic E17K mutation affect AKT1 subcellular distribution and impact on Nanog-binding dynamics to chromatin in embryonic stem cells	6
The calcifying interface in a stony coral primary polyp: An interplay between seawater and an extracellular calcifying space	6
Structural basis for cell type specific DNA binding of C/EBPβ: The case of cell cycle inhibitor p15INK4b promoter	6
Double-headed binding of myosin II to F-actin shows the effect of strain on head structure	5
Advances in computational approaches to structure determination of alphaviruses and flaviviruses using cryo-electron microscopy	5
A set of common movements within GPCR-G-protein complexes from variability analysis of cryo-EM datasets	5
Characterization of heterogeneity in nanodisc samples using Feret signatures	5
Potential implications of the glycosylation patterns in collagen α1(I) and α2(I) chains for fibril assembly and growth	5
Sub-micrometric spatial distribution of amorphous and crystalline carbonates in biogenic crystals using coherent Raman microscopy	5
Desmosomal protein structure and function and the impact of disease-causing mutations	5
On the role of the glycosylation of type I collagen in bone	5
High-resolution single-particle imaging at 100–200 keV with the Gatan Alpine direct electron detector	5
The anatomical and micromorphological properties of endemic species to gypsic soils of Semnan, Iran	5
Morphological and genetic mechanisms underlying the plasticity of the coral Porites astreoides across depths in Bermuda	5
The SIRAH force field: A suite for simulations of complex biological systems at the coarse-grained and multiscale levels	5
From viruses to humans – Exploring the structure–function relationship of the Kesv protein for the future of biomedicine	5
Dense intracellular ion pools in unicellular organisms	5
Isotope-edited vibrational circular dichroism study reveals a flexible N-terminal structure of islet amyloid peptide (NFGAIL) in amyloid fibril form: A site-specific local structural analysis	5
Structure determination and analysis of titin A-band fibronectin type III domains provides insights for disease-linked variants and protein oligomerisation	5
Structural analysis revealed a novel conformation of the NTRC reductase domain from Chlamydomonas reinhardtii	5
A key piece of the puzzle: The central tetramer of the Saccharomyces cerevisiae septin protofilament and its implications for self-assembly	5
ContinuousFlex: Software package for analyzing continuous conformational variability of macromolecules in cryo electron microscopy and tomography data	5
Evolution and biomineralization of pteropod shells	4
Outside Front Cover	4
Outside Front Cover	4
Studying protein–protein interactions: Latest and most popular approaches	4
Locating cellular contents during cryoFIB milling using cellular secondary-electron imaging	4
Structural and biochemical insights into the substrate-binding mechanism of a glycoside hydrolase family 12 β-1,3-1,4-glucanase from Chaetomium sp.	4
The role of the half-turn in determining structures of Alzheimer’s Aβ wild-type and mutants	4
Crystal structure of the phospholipase A and acyltransferase 4 (PLAAT4) catalytic domain	4
Journal of Structural Biology – Paper of the Year 2020	4
SAXS of murine amelogenin identifies a persistent dimeric species from pH 5.0 to 8.0	4
Structural basis of the partially open central gate in the human CNGA1/CNGB1 channel explained by additional density for calmodulin in cryo-EM map	4
Journal of Structural Biology – Paper of the Year 2021	4
Mitoxantrone stacking does not define the active or inactive state of USP15 catalytic domain	4
VHUT-cryo-FIB, a method to fabricate frozen hydrated lamellae from tissue specimens for in situ cryo-electron tomography	4
CryoSamba: Self-supervised deep volumetric denoising for cryo-electron tomography data	4

Outside Front Cover	4
Elucidation of critical pH-dependent structural changes in Botulinum Neurotoxin E	4
Structural and biochemical basis for the substrate specificity of Pad-1, an indole-3-pyruvic acid aminotransferase in auxin homeostasis	4
Editorial Board	4
Identification and demonstration of roGFP2 as an environmental sensor for cryogenic correlative light and electron microscopy	4
Editorial Board	4
Calcite crystal orientation patterns in the bilayers of laminated shells of benthic rotaliid foraminifera	4
Comprehensive predictions of secondary structures for comparative analysis in different species	4
Spectroscopic studies for identifying the chemical states of the periostracum of the Corbicula species in Lake Biwa	4
Computational structural biology: Evolution of the field	4
Cementum thickening leads to lower whole tooth mobility and reduced root stresses: An in silico study on aging effects during mastication	4
Imaging biological samples by integrated differential phase contrast (iDPC) STEM technique	3
Exploring the folding landscape of leptin: Insights into threading pathways	3
Identification of incorrectly oriented particles in cryo-EM single particle analysis	3
Practical considerations for using K3 cameras in CDS mode for high-resolution and high-throughput single particle cryo-EM	3
Structure of a consensus chitin-binding domain revealed by solution NMR	3
SAM1 domain of SASH1 harbors distinctive structural heterogeneity	3
Snapshots along the catalytic path of KabA, a PLP-dependent aminotransferase required for kanosamine biosynthesis in Bacillus cereus UW85	3
Single particle cryo-EM analysis of Rickettsia conorii Sca2 reveals a formin-like core	3
Unveiling success determinants for AMB-assisted phase expansion of fusion proteins in ARP/wARP	3
The biological regulation of sea urchin larval skeletogenesis – From genes to biomineralized tissue	3
CorRelator: Interactive software for real-time high precision cryo-correlative light and electron microscopy	3
Lattice micropatterning for cryo-electron tomography studies of cell-cell contacts	3
The role of S126 in the Staphylococcus equorum MnSOD activity and stability	3
The role of tandem repeats in bacterial functional amyloids	3
Isolation and reconstruction of cardiac mitochondria from SBEM images using a deep learning-based method	3
Unusual commonality in active site structural features of substrate promiscuous and specialist enzymes	3
High-throughput segmentation, data visualization, and analysis of sea star skeletal networks	3
The 3D organization of the mineralized scales of the sturgeon has structures reminiscent of dentin and bone: A FIB-SEM study	3
Anti-NSCLC activity in vitro of Hsp90N inhibitor KW-2478 and complex crystal structure determination of Hsp90N-KW-2478	3
Structural insights into the targeting specificity of ubiquitin ligase for S. cerevisiae isocitrate lyase but not C. albicans isocitrate lyase	3
An inducible model for medial calcification based on matrix Gla protein deficiency	2
Focused ion beam-SEM 3D study of osteodentin in the teeth of the Atlantic wolfish Anarhichas lupus	2
Crystal structure of the GluK1 ligand-binding domain with kainate and the full-spanning positive allosteric modulator BPAM538	2
Arabidopsis thaliana argininosuccinate lyase structure uncovers the role of serine as the catalytic base	2
Crystal structures of the fatty acid biosynthesis initiation enzymes in Bacillus subtilis	2
Characterization of SARS-CoV-2 nucleocapsid protein oligomers	2
PickYOLO: Fast deep learning particle detector for annotation of cryo electron tomograms	2
It’s noisy out there! A review of denoising techniques in cryo-electron tomography	2
GCTransNet: 3D mitochondrial instance segmentation based on Global Context Vision Transformers	2
RosettaHDX: Predicting antibody-antigen interaction from hydrogen-deuterium exchange mass spectrometry data	2
Structure and mineralization of the spearing mantis shrimp (Stomatopoda; Lysiosquillina maculata) body and spike cuticles	2
A genetic model for the secretory stage of dental enamel formation	2
Comprehensive structural overview of the C-terminal ligand-binding domains of the TetR family regulators	2
Interaction of berberine with different forms of DNA in human telomeric region	2
Molecular characterization of linker and loop-mediated structural modulation and hinge motion in the C4-C5 domains of cMyBPC	2
Challenging level of rigid-body approach involving numerical elements (CHLORAINE) applied to repeated elastin peptides	2
Porous assembly of an antifungal protein mediated by zinc and sulfonato-calix[8]arene	2
Control of crystal growth during coccolith formation by the coccolithophore Gephyrocapsa oceanica	2
DeepAlign, a 3D alignment method based on regionalized deep learning for Cryo-EM	2
NMR sample optimization and backbone assignment of a stabilized neurotensin receptor	2
Crystal structure of the anti-CRISPR repressor Aca2	2
Selective labeling of phosphatidylserine for cryo-TEM by a two-step immunogold method	2
The role of bone sialoprotein in bone healing	2
Off-axis electron holography of unstained bacteriophages: Towards electrostatic potential measurement of biological samples	2
Deep generative modeling for volume reconstruction in cryo-electron microscopy	2
Editorial Board	2