OOIR: Observatory of International Research

Papers

(The TQCC of Journal of Structural Biology is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)

Article	Citations
Keratin intermediate filament chains in the European common wall lizard (Podarcis muralis) and a potential keratin filament crosslinker	771
Tropomyosin induces the synthesis of magnesian calcite in sea urchin spines	84
Allosteric inhibition of cytosolic NADP+-dependent isocitrate dehydrogenase by oxaloacetate	53
Determination of amino acids that favour the αL region using Ramachandran propensity plots. Implications for α-sheet as the possible amyloid intermediate	39
Exploring high-resolution cryo-ET and subtomogram averaging capabilities of contemporary DEDs	34
An exon-biased biophysical approach and NMR spectroscopy define the secondary structure of a conserved helical element within the HOTAIR long non-coding RNA	33
Comparative structural, biophysical, and receptor binding study of true type and wild type AAV2	33
Disorder-to-order transition of Synaptobrevin-2: Tracing the conformational diversity of a synaptic SNARE protein	33
Spike protein fusion loop controls SARS-CoV-2 fusogenicity and infectivity	33
Calcium carbonate deposition in the spicules of the sponge Heteropia glomerosa (Porifera, Calcarea)	32
Deep Learning-based structure modelling illuminates structure and function in uncharted regions of β-solenoid fold space	31
High-resolution single-particle imaging at 100–200 keV with the Gatan Alpine direct electron detector	31
ContinuousFlex: Software package for analyzing continuous conformational variability of macromolecules in cryo electron microscopy and tomography data	29
TomoAlign: A novel approach to correcting sample motion and 3D CTF in CryoET	28
Inter-Domain interactions Slow BoNT/A’s onset of action	27
Multishot tomography for high-resolution in situ subtomogram averaging	27
Locating cellular contents during cryoFIB milling using cellular secondary-electron imaging	27
Studying protein–protein interactions: Latest and most popular approaches	24
Outside Front Cover	24
CorRelator: Interactive software for real-time high precision cryo-correlative light and electron microscopy	23
Interaction of berberine with different forms of DNA in human telomeric region	23
Cementum thickening leads to lower whole tooth mobility and reduced root stresses: An in silico study on aging effects during mastication	23
Outside Front Cover	23
Focused ion beam-SEM 3D study of osteodentin in the teeth of the Atlantic wolfish Anarhichas lupus	22
Comprehensive structural overview of the C-terminal ligand-binding domains of the TetR family regulators	22

Editorial Board	21
It’s noisy out there! A review of denoising techniques in cryo-electron tomography	21
Isolation and reconstruction of cardiac mitochondria from SBEM images using a deep learning-based method	21
Structural and kinetic analysis of the monofunctional Staphylococcus aureus PBP1	19
Crystal structure of TbAlba1 from Trypanosoma brucei	19
JBP1 and JBP3 have conserved structures but different affinity to base-J	19
Transcriptome profiling of DPP stimulated DPSCs identifies the role of autophagy in odontogenic differentiation	19
Dual pattern of cholesterol-induced decoupling of residue-residue interactions of Kir2.2	18
3D quantification of the lacunocanalicular network on human femoral diaphysis through synchrotron radiation-based nanoCT	17
ArtiaX: geometric models, camera paths and image processing tools	16
Crystal structure of the Escherichia coli CusS kinase core	16
Outside Front Cover	16
2.85 and 2.99 Å resolution structures of 110 kDa nitrite reductase determined by 200 kV cryogenic electron microscopy	16
Outside Front Cover	16
Focused classifications and refinements in high-resolution single particle cryo-EM analysis	16
Structure and heterogeneity of a highly cargo-loaded encapsulin shell	16
Structural modeling of two plant UDP-dependent sugar-sugar glycosyltransferases reveals a conserved glutamic acid residue that is a hallmark for sugar acceptor recognition	16
Metallic support films reduce optical heating in cryogenic correlative light and electron tomography	16
Structural and dynamic insights into the HNH nuclease of divergent Cas9 species	15
Automated picking of amyloid fibrils from cryo-EM images for helical reconstruction with RELION	15
A RhoA structure with switch II flipped outward revealed the conformational dynamics of switch II region	15
Cryo-EM structure of a eukaryotic zinc transporter at a low pH suggests its Zn2+-releasing mechanism	15
Local defocus estimation in single particle analysis in cryo-electron microscopy	15
New insight on spatial localization and microstructures of calcite-aragonite interfaces in adult shell of Haliotis tuberculata: Investigations of wild and farmed abalones by FTIR and Raman mapping	15
Domain crossover in the reductase subunit of NADPH-dependent assimilatory sulfite reductase	15
Outside Front Cover	15
Common structural features in some of the sequentially distant neurotransmitter transporters N-termini	14
Daisy: An integrated repeat protein curation service	14
Three dimensional structures of the inner and outer pig petrous bone using FIB-SEM: Implications for development and ancient DNA preservation	13
EMDA: A Python package for Electron Microscopy Data Analysis	13
Identification of structural determinants of nicotinamide phosphoribosyl transferase (NAMPT) activity and substrate selectivity	13
Crystal structure of breast regression protein 39 (BRP39), a signaling glycoprotein expressed during mammary gland apoptosis, at 2.6 Å resolution	12
Outside Front Cover	12
Biochemical, structural and dynamical studies reveal strong differences in the thermal-dependent allosteric behavior of two extremophilic lactate dehydrogenases	12
Cell recognition based on atomic force microscopy and modified residual neural network	12
Structural analysis of the water channel AQP2 by single-particle cryo-EM	12
Outside Front Cover	12
Assessment of scoring functions to rank the quality of 3D subtomogram clusters from cryo-electron tomography	11
Deletion within ameloblastin multitargeting domain reduces its interaction with artificial cell membrane	11
Bacterial NadQ (COG4111) is a Nudix-like, ATP-responsive regulator of NAD biosynthesis	11
Genetic basis of stony coral biomineralization: History, trends and future prospects	10
Integrating on-grid immunogold labeling and cryo-electron tomography to reveal photosystem II structure and spatial distribution in thylakoid membranes	10
Tooth acellular extrinsic fibre cementum incremental lines in humans are formed by parallel branched Sharpey’s fibres and not by its mineral phase	10
Structure and conformational variability of the HER2-trastuzumab-pertuzumab complex	10
Structural analysis of the human C5a-C5aR1 complex using cryo-electron microscopy	10
2.0 Å cryo-EM structure of the 55 kDa nucleoplasmin domain of AtFKBP53	10
A glimpse into the hidden world of the flexible C-terminal protein binding domains of human RAD52	10
DeepQs: Local quality assessment of cryo-EM density map by deep learning map-model fit score	10
Molecular insights into the binding interactions and energetics of the omicron spike variant with hACE2 and a neutralizing antibody	10
Structural insights into ring-building motif domains involved in bacterial sporulation	9

Outside Front Cover	9
Calcite crystal orientation patterns in the bilayers of laminated shells of benthic rotaliid foraminifera	9
Structural insights into the engagement of lysophosphatidic acid receptor 1 with different G proteins	9
Structural basis of O-methylation of (2-heptyl-)1-hydroxyquinolin-4(1H)-one and related compounds by the heterocyclic toxin methyltransferase Rv0560c of Mycobacterium tuberculosis	9
Outside Front Cover	9
MEPSi: A tool for simulating tomograms of membrane-embedded proteins	9
Editorial Board	9
Opportunities for biomineralization research using multiscale computed X-ray tomography as exemplified by bone imaging	9
Journal of Structural Biology – Paper of the Year 2022	9
Improving CryoEM maps of symmetry-mismatched macromolecular assemblies: A case study on the flagellar motor	9
A set of common movements within GPCR-G-protein complexes from variability analysis of cryo-EM datasets	8
Potential implications of the glycosylation patterns in collagen α1(I) and α2(I) chains for fibril assembly and growth	8
Dense intracellular ion pools in unicellular organisms	8
The crystal structure of yeast regulatory subunit reveals key evolutionary insights into Protein Kinase A oligomerization	8
NMR structure and dynamics of Q4DY78, a conserved kinetoplasid-specific protein from Trypanosoma cruzi	8
Mitoxantrone stacking does not define the active or inactive state of USP15 catalytic domain	8
Effects of Xylanase A double mutation on substrate specificity and structural dynamics	7
Crystal structures of the fatty acid biosynthesis initiation enzymes in Bacillus subtilis	7
Mean curvature motion facilitates the segmentation and surface visualization of electron tomograms	7
The role of tandem repeats in bacterial functional amyloids	7
Morphological and genetic mechanisms underlying the plasticity of the coral Porites astreoides across depths in Bermuda	7
Conformational landscape of the mycobacterial inosine 5′-monophosphate dehydrogenase octamerization interface	7
Shark centra microanatomy and mineral density variation studied with laboratory microComputed Tomography	7
Computational structural biology: Evolution of the field	7
The crystal structure of the H116Q mutant of NDM-1: An enzyme devoid of zinc ions	7
3D distribution of biomineral and chitin matrix in the stomatopod dactyl club by high energy XRD-CT	7
Desmosomal protein structure and function and the impact of disease-causing mutations	7
A key piece of the puzzle: The central tetramer of the Saccharomyces cerevisiae septin protofilament and its implications for self-assembly	7
Characterization of heterogeneity in nanodisc samples using Feret signatures	7
Evolution and biomineralization of pteropod shells	7
Identification and demonstration of roGFP2 as an environmental sensor for cryogenic correlative light and electron microscopy	7
Direct control of shell regeneration by the mantle tissue in the pearl oyster Pinctada fucata	7
Biochemical, structural and dynamical characterizations of the lactate dehydrogenase from Selenomonas ruminantium provide information about an intermediate evolutionary step prior to complete alloster	7
Sub-micrometric spatial distribution of amorphous and crystalline carbonates in biogenic crystals using coherent Raman microscopy	7
Elucidation of critical pH-dependent structural changes in Botulinum Neurotoxin E	7
Cryo-EM structure of AMP-PNP-bound human mitochondrial ATP-binding cassette transporter ABCB7	7