OOIR: Observatory of International Research

Papers

(The TQCC of Journal of Structural Biology is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)

Article	Citations
Allosteric inhibition of cytosolic NADP+-dependent isocitrate dehydrogenase by oxaloacetate	65
Deep Learning-based structure modelling illuminates structure and function in uncharted regions of β-solenoid fold space	63
Exploring high-resolution cryo-ET and subtomogram averaging capabilities of contemporary DEDs	46
Tropomyosin induces the synthesis of magnesian calcite in sea urchin spines	46
Characterization of NMDA receptor Allostery modulation	43
Calcium carbonate deposition in the spicules of the sponge Heteropia glomerosa (Porifera, Calcarea)	42
ContinuousFlex: Software package for analyzing continuous conformational variability of macromolecules in cryo electron microscopy and tomography data	41
Dual-colour super-resolution cryoCLEM in mammalian cells using the fluorescent proteins rsTagRFP and rsEGFP2	41
Inter-Domain interactions Slow BoNT/A’s onset of action	35
High-resolution single-particle imaging at 100–200 keV with the Gatan Alpine direct electron detector	34
Outside Front Cover	30
Structure of the type VI secretion protein VgrS from Salmonella Typhimurium	27
Multishot tomography for high-resolution in situ subtomogram averaging	26
Locating cellular contents during cryoFIB milling using cellular secondary-electron imaging	25
Studying protein–protein interactions: Latest and most popular approaches	23
Focused ion beam-SEM 3D study of osteodentin in the teeth of the Atlantic wolfish Anarhichas lupus	23
Outside Front Cover	22
Outside Front Cover	22
Binding of the elastin peptide VGVAPG and lactose to the human elastin binding protein	21
3DDF-VAE: Dual-frequency variational autoencoder with pose-consistency validation for rare cryo-EM conformation discovery	21
Changes in Arabidopsis thaliana seedling cell wall assembly induced by treatment with Yariv reagent – Molecular features & visualization with immunocytochemistry and a fluorescent Yariv reagent	21
Comprehensive structural overview of the C-terminal ligand-binding domains of the TetR family regulators	18
Transcriptome profiling of DPP stimulated DPSCs identifies the role of autophagy in odontogenic differentiation	17
Interaction of berberine with different forms of DNA in human telomeric region	17
Editorial Board	16

Nanostructural evolution during carious and demineralisation process of human dentine using small angle X-ray scattering tensor tomography	16
Dual pattern of cholesterol-induced decoupling of residue-residue interactions of Kir2.2	16
3D quantification of the lacunocanalicular network on human femoral diaphysis through synchrotron radiation-based nanoCT	16
G-Quadruplex structures within the hfq gene regulate RNA–protein interactions in Acinetobacter baumannii	15
Leveraging deep learning semantic segmentation for imaging coral skeletons	15
Structure and heterogeneity of a highly cargo-loaded encapsulin shell	15
From selenium to sulfur: predictive modeling unveils conformational and bonding changes in selenoproteins	14
JBP1 and JBP3 have conserved structures but different affinity to base-J	14
ArtiaX: geometric models, camera paths and image processing tools	13
Insights into the pathogenic mechanisms associated with the SARS-CoV-2 spike protein	13
Structural and kinetic analysis of the monofunctional Staphylococcus aureus PBP1	13
Focused classifications and refinements in high-resolution single particle cryo-EM analysis	12
Metallic support films reduce optical heating in cryogenic correlative light and electron tomography	12
Outside Front Cover	12
Nickel-NTA lipid-monolayer affinity grids allow for high-resolution structure determination by cryo-EM	12
New insight on spatial localization and microstructures of calcite-aragonite interfaces in adult shell of Haliotis tuberculata: Investigations of wild and farmed abalones by FTIR and Raman mapping	12
Cryo-EM structure of a eukaryotic zinc transporter at a low pH suggests its Zn2+-releasing mechanism	12
Crystal structure of the Escherichia coli CusS kinase core	12
Daisy: An integrated repeat protein curation service	11
A RhoA structure with switch II flipped outward revealed the conformational dynamics of switch II region	11
Local defocus estimation in single particle analysis in cryo-electron microscopy	11
Common structural features in some of the sequentially distant neurotransmitter transporters N-termini	11
Domain crossover in the reductase subunit of NADPH-dependent assimilatory sulfite reductase	11
Identification of structural determinants of nicotinamide phosphoribosyl transferase (NAMPT) activity and substrate selectivity	10
Preferential binding as a driving mechanism of lipid domains formation	10
Bacterial NadQ (COG4111) is a Nudix-like, ATP-responsive regulator of NAD biosynthesis	10
Outside Front Cover	10
Local microenvironments of capsomer variants in the PBCV-1	10
Molecular insights into the binding interactions and energetics of the omicron spike variant with hACE2 and a neutralizing antibody	10
DeepQs: Local quality assessment of cryo-EM density map by deep learning map-model fit score	10
Three dimensional structures of the inner and outer pig petrous bone using FIB-SEM: Implications for development and ancient DNA preservation	10
Deletion within ameloblastin multitargeting domain reduces its interaction with artificial cell membrane	10
A glimpse into the hidden world of the flexible C-terminal protein binding domains of human RAD52	10
Structure and conformational variability of the HER2-trastuzumab-pertuzumab complex	9
Cholesterol crystals in reservosomes of Trypanosoma cruzi	9
Corrigendum to “High-resolution single particle analysis using a scintillator camera XF416 on CRYOARM300II at 300 kV”. [J. Struct. Biol. 218(1) (2026) 108286]	9
Outside Front Cover	9
Cell recognition based on atomic force microscopy and modified residual neural network	9
Structural analysis of the water channel AQP2 by single-particle cryo-EM	9
Structural insights into the engagement of lysophosphatidic acid receptor 1 with different G proteins	9
2.0 Å cryo-EM structure of the 55 kDa nucleoplasmin domain of AtFKBP53	9
Tooth acellular extrinsic fibre cementum incremental lines in humans are formed by parallel branched Sharpey’s fibres and not by its mineral phase	9
Structural analysis of the human C5a-C5aR1 complex using cryo-electron microscopy	9
Outside Front Cover	9
Distribution and size of scallop patterns at the human dentin enamel junction revealed with micro tomography	9
Journal of Structural Biology – Paper of the Year 2022	8
Characterization of heterogeneity in nanodisc samples using Feret signatures	8
Mitoxantrone stacking does not define the active or inactive state of USP15 catalytic domain	8
Conformational landscape of the mycobacterial inosine 5′-monophosphate dehydrogenase octamerization interface	8
Sub-micrometric spatial distribution of amorphous and crystalline carbonates in biogenic crystals using coherent Raman microscopy	8

Outside Front Cover	8
Improving CryoEM maps of symmetry-mismatched macromolecular assemblies: A case study on the flagellar motor	8
A key piece of the puzzle: The central tetramer of the Saccharomyces cerevisiae septin protofilament and its implications for self-assembly	8
Computational structural biology: Evolution of the field	8
Potential implications of the glycosylation patterns in collagen α1(I) and α2(I) chains for fibril assembly and growth	8
Editorial Board	8
Outside Front Cover	8
Morphological and genetic mechanisms underlying the plasticity of the coral Porites astreoides across depths in Bermuda	8
MEPSi: A tool for simulating tomograms of membrane-embedded proteins	8
Effects of Xylanase A double mutation on substrate specificity and structural dynamics	7
Elucidation of critical pH-dependent structural changes in Botulinum Neurotoxin E	7
Cryo-Electron Microscopy: The field of 1,000+ methods	7
Crystal structures of the fatty acid biosynthesis initiation enzymes in Bacillus subtilis	7
Identification and demonstration of roGFP2 as an environmental sensor for cryogenic correlative light and electron microscopy	7
Journal of Structural Biology – Paper of the Year 2021	7
Insight into structural biophysics from solution X-ray scattering	7
The intricacies of tooth enamel: Embryonic origin, development and human genetics	7
Announcement: Journal of Structural Biology: Paper of the year	7
Quantitative 3D electron microscopy characterization of mitochondrial structure, mitophagy, and organelle interactions in murine atrial fibrillation	7
Biochemical, structural and dynamical characterizations of the lactate dehydrogenase from Selenomonas ruminantium provide information about an intermediate evolutionary step prior to complete alloster	7
The role of tandem repeats in bacterial functional amyloids	7
Direct control of shell regeneration by the mantle tissue in the pearl oyster Pinctada fucata	7
A new algorithm for particle weighted subtraction to decrease signals from unwanted components in single particle analysis	7
Editorial Board	7
3D distribution of biomineral and chitin matrix in the stomatopod dactyl club by high energy XRD-CT	7
Outside Front Cover	7
Mechanistic study of PDE5A inhibitors from the prepared folium of Epimedium sagittatum maxim	7
The crystal structure of the H116Q mutant of NDM-1: An enzyme devoid of zinc ions	7
Sequence/structural/functional relationships between Ganoderma fungal immunomodulatory proteins (gFIPs) and proteins involved in the modulation of immune response	7
Bioinformatic and experimental characterization of the RBM15 RNA binding protein	7
Membrane and vesicle structure detection in cryo-electron tomography based on deep learning	7
Determinants of site-selectivity in human ileal bile acid-binding protein by NMR dynamic analysis of a functionally-impaired mutant	7