OOIR: Observatory of International Research

Papers

(The TQCC of Thyroid is 12. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
Role of Thyrotropin-Releasing Hormone in Regulating Fibroblast Growth Factor 21 in Mouse Pancreatic β Cells	552
Future Meetings	273
35th Anniversary of Thyroid—Journal of the American Thyroid Association	207
Rosalind Franklin Society Proudly Announces the 2023 Award Recipient for Thyroid	142
Regular Call Oral Abstracts	113
International Women’s Day: An Occasion for a Tribute to Women Leaders in the American Thyroid Association	108
Minimally Invasive Ablative Treatments for Benign Thyroid Nodules: Current Evidence and Future Directions	95
Re: “Active Surveillance Outcomes of Patients with Low-Risk Papillary Thyroid Microcarcinoma According to Levothyroxine Treatment Status” by Yamamoto et al.	89
Stage-Dependent Death Hazard and Conditional Survival of Patients with Papillary Thyroid Cancer	84
A Novel Levothyroxine Solution Results in Similar Bioavailability Whether Taken 30 or Just 15 Minutes Before a High-Fat High-Calorie Meal	82
Letter to the Editor: ETV6-NTRK2 Fusion Identified in a Patient with Medullary Thyroid Carcinoma	81
Molecular and Clinical Features of Congenital Hypothyroidism Due to Multiple DUOX2 Variants	73
A Conversation with Samuel Refetoff, MD: How Treating One Family Stimulated a Lifelong Series of Major Discoveries in Thyroid Physiology and Disease	70
The Epidemiology of Thyroid Eye Disease in Olmsted County, Minnesota, 2005–2020	64
A Comprehensive Review of Thyroid Hormone Metabolism in the Gut and Its Clinical Implications	61
A Multicenter, Single-Blind, Case-Control, Immunohistochemical Study of Orbital Tissue in Thyroid Eye Disease	59
Investigating Levothyroxine Use and Its Association with Thyroid Health in Patients with Hypothyroidism: A Community Pharmacy Study	57
Effects of Triiodothyronine Treatment in an Animal Model of Heart Failure with Preserved Ejection Fraction	53
Incidental Thyroid Nodules on Computed Tomography: A Systematic Review and Meta-Analysis Examining Prevalence, Follow-Up, and Risk of Malignancy	48
Radiofrequency Ablation of Low-Risk Papillary Thyroid Microcarcinoma: A Retrospective Cohort Study Including Patients with More than 10 Years of Follow-up	45
Discoveries Around the Hypothalamic–Pituitary–Thyroid Axis	43
Development and Progression of Thyroid Disease in PTEN Hamartoma Tumor Syndrome: Refined Surveillance Recommendations	43
Correction to: The Diagnostic Value of ¹⁸ F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography in Differe	41
Preliminary Evidence of Potential Association Between Exposure to Estriol-Containing Skincare Cosmetics Sold in China and Autoimmune Thyroid Disease	41
The American Thyroid Association 1923–2023: Honoring Our Past, Embracing Our Future	40

The Year in Thyroidology: Surgical Science	39
Abstract Author Index	39
Preliminary Results of a Double-Blind Randomized Controlled Trial Evaluating the Cardiometabolic Effects of Levothyroxine and Liothyronine Compared to Levothyroxine with Placebo in Athyreotic Low-Risk	37
Letter to the Editor: Remission of Graves' Disease After Initiation of Ocrelizumab in Patients with Multiple Sclerosis	36
Delayed Thyrotropin Rise in Preterm Newborns: Value of Multiple Screening Samples and of a Detailed Clinical Characterization	36
A Qualitative Thematic Analysis Exploring Chinese Young Adults’ Experiences in Decision Making on the Management of Low-Risk Papillary Thyroid Cancer	35
Optimizing Diagnostic Accuracy of Fine Needle Aspiration Biopsy Calcitonin Measurements in Detecting Medullary Thyroid Carcinoma	34
Subclinical Hyperthyroidism, Cardiovascular Disease and All-Cause Mortality: Insights from a Large Dutch Primary Care Cohort Study	34
Improved Diagnostic Accuracy of Thyroid Fine-Needle Aspiration Cytology with Artificial Intelligence Technology	33
Thyroid Cancer Risk with GLP-1 Receptor Agonists: Evidence, Knowledge Gaps, and the Path Forward	32
Incidence and Temporal Patterns of Differentiated Thyroid Carcinoma in Children and Adolescents in Germany: A Pooled Analysis Based on Data from the German Malignant Endocrine Tumor Registry and the G	32
Increased Progression-Free Survival with Cabozantinib Versus Placebo in Patients with Radioiodine-Refractory Differentiated Thyroid Cancer Irrespective of Prior Vascular Endothelial Growth Factor Rece	32
Medullary Thyroid Cancer with Ectopic Cushing's Syndrome: A Case Report and Systematic Review of Detailed Cases from the Literature	31
The Epidemiological Landscape of Thyroid Cancer and Estimates of Overdiagnosis in China: A Population-Based Study	31
A Case Report of Poor Response to Selpercatinib in the Presence of a 632_633 RET Deletion	31
Remote-Access Thyroidectomy and Parathyroidectomy: A 2025 Consensus Statement from the Asia-Pacific Society of Thyroid Surgery, American Head and Neck Society, American Association of Endocrine Surgeo	30
A Preliminary Analysis of Thyrotropin Measurement from Finger Stick Dried Blood Spot with an Automated High-Throughput Immunoassay Analyzer	30
Clinicopathologic Characteristics of Pediatric Follicular Variant of Papillary Thyroid Carcinoma Subtypes: A Retrospective Cohort Study	29
Understanding the Brain Manifestations of Hypothyroidism in Adult Patients	29
All-Cause and Cause-Specific Mortality Among Low-Risk Differentiated Thyroid Cancer Survivors in the United States	29
Disulfide Bonds of Thyroid Peroxidase Are Critical Elements for Subcellular Localization, Proteasome-Dependent Degradation, and Enzyme Activity	28
Re: “Barriers and Facilitators to the Choice of Active Surveillance for Low-Risk Papillary Thyroid Cancer in China: A Qualitative Study Examining Patient Perspectives” by Zhu et al.: Clinical Factors	28
Clinical and Surgical Year in Review	28
Correction to : Exploring the Genetic Link Between Thyroid Dysfunction and Common Psychiatric Disorders: A Specific Hormonal or a General Autoimmune Comorbidity by Soheili-N	27
Future Meetings	27
Regular Call Oral Abstracts	26
Novel Deiodinase 2-Selective Inhibitors—Possible Reference Substances for Regulatory In Vitro Tests for Endocrine Disruptors and Drugs Targeting T3-Depen	26
Regional Differences in the Management of Thyroid Eye Disease: Results from an International Clinical Practice Survey of Endocrinologists	26
Patient-Reported Outcomes Three Years After Deciding on Surgery or Active Surveillance for Small, Low-Risk Papillary Thyroid Cancer: Results of a Prospective Cohort Study	26
Social Vulnerability Association with Thyroid Cancer Disparities in the United States	26
Tumor Growth Kinetics Based on Initial Tumor Volume Doubling Time in Active Surveillance of Low-Risk Papillary Thyroid Carcinoma	26
Partial Resistance to Thyroid Hormone–Induced Tachycardia and Cardiac Hypertrophy in Mice Lacking Thyroid Hormone Receptor β	25
Trends in Iodine Status Among U.S. Children and Adults: A Cross-Sectional Analysis of National Health and Nutrition Examination Survey Data from 2001–2004 to 2017–2020	25
The 2023 Bethesda System for Reporting Thyroid Cytopathology	25
Estimating Incidence and Case Fatality of Thyroid Storm in Germany Between 2007 and 2017: A Claims Data Analysis	25
Beyond Salt Iodization: Sustained Population Sufficiency and Recurrence of Iodine Deficiency in Pregnant Women in Iran	25
A Novel Approach to Targeting DLL3 with Tarlatamab in a Patient with Medullary Thyroid Carcinoma after Progression on Selpercatinib	25
Active Surveillance of Differentiated Thyroid Cancer Metastatic Cervical Lymph Nodes: A Retrospective Single-Center Cohort Study	25
Radioactive Iodine: A Living History	24
Germline Telomere-Regulating Gene Variants Are Not Associated with Thyroid Cancer in a Saudi Arabian Population	24
Alkylating Agent-Induced High Tumor Mutational Burden in Medullary Thyroid Cancer and Response to Immune Checkpoint Inhibitors: Two Case Reports	24
Future Meetings	24
Future Meetings	24
Response to Korff re: “Thyroid Eye Disease: A New Name, a New Guide, and a New Era”	24
Prognostic Thresholds for Lymph Node Metastasis in Medullary Thyroid Cancer: A Restricted Cubic Splines Analysis	23
Correction to: A Comprehensive Review of Thyroid Hormone Metabolism in the Gut and Its Clinical Implications by Fenneman et al. Thyroid 2023;33(1):32–44; doi: 10.1089/thy.20	23
Association Between Metabolic Dysfunction-Associated Steatotic Liver Disease and Thyroid Cancer	23
TSH Reference Intervals: Their Importance and Complexity	23
Active Surveillance of Papillary Thyroid Cancer: Frequency and Time Course of the Six Most Common Tumor Volume Kinetic Patterns	22
Cytologic and Molecular Assessment of Isthmus Thyroid Nodules and Carcinomas	22

Management of Thyroid Eye Disease: A Consensus Statement by the American Thyroid Association and the European Thyroid Association	22
An Undetectable Postoperative Calcitonin Level Is Associated with Long-Term Disease-Free Survival in Medullary Thyroid Carcinoma: Results of a Retrospective Cohort Study	22
The Prevention of Iodine Deficiency: A History	21
Dynamic Risk Assessment Using Unstimulated Serum Thyroglobulin Level and Thyroglobulin Doubling Rate after Total Thyroidectomy for Papillary Thyroid Carcinoma	21
The Association Between Thyrotropin and Clinically Relevant Depression: A Retrospective Cross-Sectional Study	21
Controversies Surrounding IGF-I Receptor Involvement in Thyroid-Associated Ophthalmopathy	21
Clinical Outcomes of Radioactive Iodine Redifferentiation Therapy in Previously Iodine Refractory Differentiated Thyroid Cancers	21
Rates of Detecting Thyroid Nodules Recommended for Biopsy with Ultrasound: Are All Indications Equal?	21
Identification and Characterization of Highly Potent and Isoenzyme-Selective Inhibitors of Deiodinase Type I via a Nonradioactive High-Throughput Screening Method	20
Impact of Definitive Surgery for Graves' Disease on Adolescent Disease-Specific Quality of Life and Psychosocial Functioning	20
Future Meetings	20
Orlo H. Clark, MD (1941–2022)	20
Corrigendum to: 2016 American Thyroid Association Guidelines for Diagnosis and Management of Hyperthyroidism and Other Causes of Thyrotoxicosis	20
Changes in the Volume and Diameter of Benign Thyroid Nodules: A 10-Year Follow-Up Study	20
Utility of Ultrasound Surveillance for Thyroid Cancer in Children	20
Response to Mooij and van Trotsenburg re: “Exploring the Genetic Link Between Thyroid Dysfunction and Common Psychiatric Disorders: A Specific Hormonal or a General Autoimmune Comorbidity”	20
Meeting Program and Abstracts	20
Characterization of the Thyroid Cancer Genomic Landscape by Plasma-Based Circulating Tumor DNA Next-Generation Sequencing	19
Rural-Urban Disparities in the Continuum of Thyroid Cancer Care: Analysis of 92,794 Cases	19
Sex Differences in Risk for Iatrogenic Thyrotoxicosis Among Older Adults: An Analysis from Real-World Clinical Data	19
A Comparison of Outcomes in Medullary Thyroid Carcinoma Patients With and Without a Preoperative Diagnosis: A Multicenter Retrospective Cohort Study	19
Inhibition of Thyroid Hormone Signaling in the Zona Incerta Alters Basal Metabolic Rate, Behavior, and Serum Glucocorticoids in Male Mice	19
Temporal Glycemic Patterns During IGF-1R Inhibitor Therapy for Thyroid Eye Disease: A Pooled Analysis of Two Clinical Trials	19
Finnish-Enriched SLC26A7 Variant in Congenital Hypothyroidism: Clinical Spectrum, Thyroid Histopathology, and Expression Analysis	19
Comparison of Postoperative Unfavorable Events in Patients with Low-Risk Papillary Thyroid Carcinoma: Immediate Surgery Versus Conversion Surgery Following Active Surveillance	19
Subclinical Hypothyroidism and Incident Depression in Adolescents and Young Adults: Results from a Nationwide Representative Prospective Study	19
Menopause-Related Health Outcomes in Women with Differentiated Thyroid Carcinoma Receiving Long-Term TSH Suppression after Total Thyroidectomy	18
Mortality Risks Associated with Antithyroid Drugs, Radioactive Iodine, and Surgery for Hyperthyroidism: A Systematic Review and Network Meta-Analysis	18
Considerations in the Diagnosis and Management of Thyroid Dysfunction in Older Adults	18
Hypothyroidism and Somatization: Results from E-Mode Patient Self-Assessment of Thyroid Therapy, a Cross-Sectional, International Online Patient Survey	18
Checkpoint Inhibition in Addition to Dabrafenib/Trametinib for BRAF ^V600E -Mutated Anaplastic Thyroid Carcinoma	18
American Thyroid Association 2026 Guidelines for Thyroid Disease in Preconception, Pregnancy, and Postpartum	18
Genetic Rescue of a Subset of Thyroid Follicular Cells Restores Thyroid Function in Dyshormonogenic Duoxa ^−/−	18
Prognostic Factors in Thyroid Cancer Patients With Brain Metastases: A Systematic Review and Meta-Analysis	18
A Systematic Review and Meta-Analysis Examining the Risk of Adverse Pregnancy and Neonatal Outcomes in Women with Isolated Hypothyroxinemia in Pregnancy	18
Precautionary Behaviors and Side Effects after Radioiodine for Thyroid Disease: A Prospective Cohort Study	18
Corrigendum to: A Phase 2 Study of Encorafenib in Combination with Binimetinib in Patients with Metastatic BRAF -Mutated Thyro	17
Abstract Author Index	17
MERAIODE: A Phase II Redifferentiation Trial with Trametinib and ¹³¹ I in Metastatic Radioactive Iodine Refractory RAS	17
Reimagining the Therapeutic Approach for Anaplastic Thyroid Cancer: The Roadmap to a Cure	17
The Origin of Antithyroid Drugs	17
A Disproportionality Analysis of the Adverse Effect Profiles of Methimazole and Propylthiouracil in Patients with Hyperthyroidism Using the Japanese Adverse Drug Event Report Database	17
The Association of Number of Retrieved Lymph Nodes with Oncologic Outcomes in Patients with Papillary Thyroid Cancer with Lateral Cervical Nodal Metastasis	16
Inhibition of MEK Signaling Attenuates Cancer Stem Cell Activity in Anaplastic Thyroid Cancer	16
The Diagnostic Value of ¹⁸ F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography in Differentiated Thyroid Cancer Patients with Eleva	16
Response to Toraih et al. re: “Chasing π-fection in Thyroidology”	16
The Treatment of Advanced Thyroid Cancer Using Pemetrexed Monotherapy or with Platinum-Based Chemotherapy	16
Disparities in Initial Thyroid Cancer Care by Hospital Treatment Volume: Analysis of 52,599 Cases in California	16
Year in Thyroidology: Basic Science	16
Equitable Solutions Are Needed for Patients Who Seek Treatment for Thyroid Cancer at Ultra-Low-Volume Hospitals	16
A Comprehensive Study on the Diagnosis and Management of Noninvasive Follicular Thyroid Neoplasm with Papillary-Like Nuclear Features	16
Identification of P21 (CDKN1A) Activated Kinase 4 as a Susceptibility Gene for Familial Non-Medullary Thyroid Carcinoma	16
Possible Primary Thyroid Nuclear Protein in Testis Carcinomas with NSD3::NUTM1 Translocation Revealed by RNA Sequencing: A Report of Two Cases	16
Clinicopathologic Characteristics and Postsurgical Follow-Up of Noninvasive Follicular Thyroid Neoplasm with Papillary-Like Nuclear Features in the Postnomenclature Revision Era	16
Correction to : “Effects of Levothyroxine Treatment on Fertility and Pregnancy Outcomes in Subclinical Hypothyroidism: A Systematic Review and Meta-Analysis of Randomized Co	16
Chronic Iodine Excess and Aging Synergistically Impact Thyrotropin Elevation: A Prospective 20-Year Follow-Up Study in China	16
Thyroid Nodules with Indeterminate Cytology and Negative Molecular Profile: Prevalence of Malignancy and Practice Paradigms for Surveillance	16
Thyroid Nodule Sphericity Metrics Discriminate Benign and Malignant Follicular and Oncocytic Neoplasms	16
Future Meetings	16
Late Breaking Abstracts	15
Trends in Survival and Factors Associated with Survival in Primary Thyroid Lymphoma: A SEER-Based Analysis (1975–2021)	15
Obesity, Physical Activity, and Thyroid Cancer Risk: Disentangling True Associations from Detection Bias	15
Performance of a Multigene Genomic Classifier in Thyroid Nodules with Suspicious for Malignancy Cytology	15
Relationship Between Physical Activity Levels and Thyroid Cancer Risk: A Prospective Cohort Study in Korea	15
Thyroid Hormones Act as a Timer for the Postnatal Maturation of Parvalbumin Neurons in Mouse Neocortex	15
Clinical and Pathological Factors Associated with Disease Persistence in Pediatric Patients with Differentiated Thyroid Carcinoma	15
Thyroid Hormone Analogs: Recent Developments	15
Response to Fitzgerald et al. re: “Thyroid Stimulating Hormone and Thyroid Hormones (Triiodothyronine and Thyroxine): An American Thyroid Association-Commissioned Review of Current Clinical and Labora	15
Effective Inhibition of Thyroid Antigen Presentation Using Retro-Inverso Peptides in Experimental Autoimmune Thyroiditis: A Pathway Toward Immune Therapies of Thyroid Autoimmunity	15
Incidental Thyroid Nodules on Computed Tomography: A Radiologist's Perspective	15
Canonical and Noncanonical Contribution of Thyroid Hormone Receptor Isoforms Alpha and Beta to Cardiac Hypertrophy and Heart Rate in Male Mice	15
The American Thyroid Association Multidisciplinary Consensus Statement on Ambulatory Thyroid Surgery	15
Thyroid Hormone Synthesis Without Thyroglobulin	14
Characterizing Thyroid Hormone Replacement, Baseline Thyrotropin, and Survival in Immune Checkpoint Inhibitor–Associated Thyroid Dysfunction	14
Long-Term Scar Perception and Quality of Life After Open Thyroidectomy in Chinese Patients: A Cross-Sectional Survey Study	14
Tumor-Infiltrating Lymphocytes Assessed Using the International TILs Working Group System Are Not Prognostic in Medullary Thyroid Cancer	14
Real-World Experience with Lenvatinib plus Pembrolizumab in Metastatic BRAF Wild-Type Anaplastic Thyroid Carcinoma	14
GLP-1 Receptor Signaling Has Different Effects on the Perikarya and Axons of the Hypophysiotropic Thyrotropin-Releasing Hormone Synthesizing Neurons in Male Mice	14
Understanding the Factors That Influence Shared-Decision Making Around Surgical Resection of Low-Risk Thyroid Cancers: A Prospective Qualitative Study	14
Survival Outcomes and Treatment Strategies in Primary Thyroid Lymphoma: A Population-Based Study of 401 Cases from the Tokyo Cancer Registry	14

Hypothalamic Thyroid Hormone Receptor α1 Signaling Controls Body Temperature	14
General Principles for the Safe Performance, Training, and Adoption of Ablation Techniques for Benign Thyroid Nodules: An American Thyroid Association Statement	14
Epigenome-Wide Association Study Reveals CpG Sites Associated with Thyroid Function and Regulatory Effects on KLF9	13
High Prevalence of TBC1D12 5′UTR Mutations in Anaplastic Thyroid Cancer	13
Papillary Thyroid Carcinomas with Tall Cell Features: An Intermediate Entity Between Classic and Tall Cell Subtypes	13
Large (>4 cm) Intrathyroidal Encapsulated Well-Differentiated Follicular Cell-Derived Carcinoma Without Vascular Invasion May Have Negligible Risk of Recurrence Even When Treated with Lobectomy Alo	13
Future Meetings	13
Acknowledgment of Reviewers 2024	13
American Thyroid Association Policy Statement: Impact of Changes in Fine Needle Aspiration Biopsy Reimbursement on Clinical Care of Patients with Thyroid Nodules in the United States	13
Towards Personalized TSH Reference Ranges: A Genetic and Population-Based Approach in Three Independent Cohorts	13
Variable Diagnoses in Cases Referred for Discordant Thyroid Function Tests: Focus on Lymphoproliferative Disorders	13
Future Meetings	13
Comparative Analysis of Taxonomic and Functional Gut Microbiota Profiles in Relation to Seroconversion of Thyroid Peroxidase Antibodies in Euthyroid Participants	13
Blocking CDK7-Mediated NOTCH1-cMYC Signaling Attenuates Cancer Stem Cell Activity in Anaplastic Thyroid Cancer	13
Response to Yan et al. re: “Could Radioactive Iodine Be a Preferred Therapy for Graves' Hyperthyroidism Patients with Large Goiters? A Viewpoint from China”	13
Levothyroxine Treatment of Subclinical Hypothyroidism and the Risk of Adverse Cardiovascular Events	12
Autoimmune Thyroiditis and Risk of Malignancy in Children with Thyroid Nodules	12
Predictive Model for Graves' Ophthalmopathy in Patients with New-Onset Graves' Disease	12
Transcriptome of Anaplastic Thyroid Cancer Reveals Two Molecular Subtypes with Distinct Tumor Microenvironment and Prognosis	12
Long-Term Clinical Outcomes of Patients with Differentiated Thyroid Cancer Treated with Lenvatinib: Results from Real-World Practice in Japan	12
Comparison of Perioperative Outcomes in Patients with Graves' Disease Undergoing Total Thyroidectomy With or Without Near Infrared Autofluorescence Imaging	12
Assessment of the Diagnostic Performance of a Commercially Available Artificial Intelligence Algorithm for Risk Stratification of Thyroid Nodules on Ultrasound	12
Dynamic Screening of Thyroid Function for the Timely Diagnosis of Congenital Hypothyroidism in Very Preterm Infants: A Prospective Multicenter Cohort Study	12
Graves’ Orbitopathy and Anophthalmia	12
Thyroid Stimulating Hormone and Thyroid Hormones (Triiodothyronine and Thyroxine): An American Thyroid Association-Commissioned Review of Current Clinical and Laboratory Status	12
Reporting of Incidental Thyroid Nodules on Chest Computed Tomography and the Impact on Nodule Evaluation: A Retrospective Cohort Study	12
The Natural Course of Low-Risk Papillary Thyroid Microcarcinoma During Pregnancy: A Prospective Active Surveillance Study	12
Euthyroidism and Long-Term Remission of Graves’ Hyperthyroidism Following Treatment With an FcRn Blocker: A Case Report	12
Association Between Long-Term Exposure to Environmental Fine Particulate Matter and the Prevalence of Thyroid Disorders: A National Cross-Sectional Study in China	12
Contactin 6, A Novel Causative Gene for Congenital Hypothyroidism, Mediates Thyroid Hormone Biosynthesis Through Notch Signaling	12
BRAF ^V600E /p-ERK/p-DRP1(Ser616) Promotes Tumor Progression and Reprogramming of Glucose Metabolism in Papillary Thyroid Cancer	12
The Incidence of Cardiovascular Disease Events in Women with Hypothyroidism: The Study of Women’s Health Across the Nation	12
Thyroid Cancer Survivors Experience Persistent Symptoms and Health-Related Quality-of-Life Deficits 12 Months Following Surgery	12