OOIR: Observatory of International Research

Papers

(The median citation count of Reviews in Medical Virology is 6. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-05-01 to 2024-05-01.)

Article	Citations
Predictors of COVID‐19 severity: A literature review	536
Interleukin‐6 in Covid‐19: A systematic review and meta‐analysis	458
Evolution of the SARS‐CoV‐2 omicron variants BA.1 to BA.5: Implications for immune escape and transmission	286
Covid‐19 and kidney injury: Pathophysiology and molecular mechanisms	205
Covid‐19 vaccines and variants of concern: A review	193
Clinical characteristics and outcomes of pregnant women with COVID‐19 and comparison with control patients: A systematic review and meta‐analysis	164
Neutralising antibody escape of SARS‐CoV‐2 spike protein: Risk assessment for antibody‐based Covid‐19 therapeutics and vaccines	124
Covid‐19 and dengue: Double punches for dengue‐endemic countries in Asia	107
Why the elderly appear to be more severely affected by COVID‐19: The potential role of immunosenescence and CMV	94
Loop‐mediated isothermal amplification (LAMP): An effective molecular point‐of‐care technique for the rapid diagnosis of coronavirus SARS‐CoV‐2	93
A brief review of interplay between vitamin D and angiotensin‐converting enzyme 2: Implications for a potential treatment for COVID‐19	89
Using heat to kill SARS‐CoV‐2	86
Proposed subtypes of post‐COVID‐19 syndrome (or long‐COVID) and their respective potential therapies	86
Microfluidic devices for detection of RNA viruses	82
Azithromycin in viral infections	81
An overview on the seven pathogenic human coronaviruses	79
An overview of the immune mechanisms of viral myocarditis	77
Sex‐based differences in severity and mortality in COVID‐19	77
Present variants of concern and variants of interest of severe acute respiratory syndrome coronavirus 2: Their significant mutations in S‐glycoprotein, infectivity, re‐infectivity, immune escape and v	68
Comparison of influenza type A and B with COVID‐19: A global systematic review and meta‐analysis on clinical, laboratory and radiographic findings	67
Efficacy and safety of remdesivir in hospitalized Covid‐19 patients: Systematic review and meta‐analysis including network meta‐analysis	67
Immunopathology and immunotherapeutic strategies in severe acute respiratory syndrome coronavirus 2 infection	65
Cardiac complications following mRNA COVID‐19 vaccines: A systematic review of case reports and case series	64
SARS‐CoV‐2 infection in people living withHIV: a systematic review	60
Immune response following infection with SARS‐CoV‐2 and other coronaviruses: A rapid review	59

Covid‐19 and oral diseases: Crosstalk, synergy or association?	58
The unique features of SARS‐CoV‐2 transmission: Comparison with SARS‐CoV, MERS‐CoV and 2009 H1N1 pandemic influenza virus	56
Quantifying the risk of SARS‐CoV‐2 reinfection over time	54
Comparison of confirmed COVID‐19 with SARS and MERS cases ‐ Clinical characteristics, laboratory findings, radiographic signs and outcomes: A systematic review and met	52
Diagnostic accuracy of serological tests and kinetics of severe acute respiratory syndrome coronavirus 2 antibody: A systematic review and meta‐analysis	52
Potential detrimental role of soluble ACE2 in severe COVID‐19 comorbid patients	52
YouTube as a source of patient information for Coronavirus Disease (COVID‐19): A content‐quality and audience engagement analysis	51
Global prevalence and genotype distribution of norovirus infection in children with gastroenteritis: A meta‐analysis on 6 years of research from 2015 to 2020	50
Innate immune evasion by SARS‐CoV‐2: Comparison with SARS‐CoV	50
Potency of BNT162b2 and mRNA‐1273 vaccine‐induced neutralizing antibodies against severe acute respiratory syndrome‐CoV‐2 variants of concern: A systematic review of in vitro studies	49
How artificial intelligence may help the Covid‐19 pandemic: Pitfalls and lessons for the future	49
Airborne transmission of SARS‐CoV‐2 via aerosols	48
The basic reproduction number of SARS‐CoV‐2 in Wuhan is about to die out, how about the rest of the World?	48
Immunity and inflammatory biomarkers in COVID‐19: A systematic review	47
C‐reactive protein as an effector molecule in Covid‐19 pathogenesis	46
Covid‐19: Time for a paradigm change	46
Alpha‐1‐antitrypsin: A possible host protective factor against Covid‐19	45
Seroprevalence of anti‐SARS‐CoV‐2 antibodies in Africa: A systematic review and meta‐analysis	44
Oral manifestations of Covid‐19‐A literature review	42
Genetic polymorphisms of ACE1, ACE2, and TMPRSS2 associated with COVID‐19 severity: A systematic review with meta‐analysis	42
Severe acute respiratory syndrome‐coronavirus‐2 spike (S) protein based vaccine candidates: State of the art and future prospects	41
Efficacy and secondary infection risk of tocilizumab, sarilumab and anakinra in COVID‐19 patients: A systematic review and meta‐analysis	40
Altered gut microbial metabolites could mediate the effects of risk factors in Covid‐19	39
Classical and alternative receptors for SARS‐CoV‐2 therapeutic strategy	39
Influenza vaccines: Past, present, and future	37
A systematic meta‐analysis of immune signatures in patients with COVID‐19	37
Three months of COVID‐19: A systematic review and meta‐analysis	36
Respiratory viral co‐infections in patients with COVID‐19 and associated outcomes: A systematic review and meta‐analysis	35
Long‐term side effects and lingering symptoms post COVID‐19 recovery	35
Update on the omicron sub‐variants BA.4 and BA.5	35
Global and regional circulation trends of norovirus genotypes and recombinants, 1995–2019: A comprehensive review of sequences from public databases	34
Viral infection neutralization tests: A focus on severe acute respiratory syndrome‐coronavirus‐2 with implications for convalescent plasma therapy	34
The role of endogenous retroviruses‐K in human cancer	33
Baseline physical activity is associated with reduced mortality and disease outcomes in COVID‐19: A systematic review and meta‐analysis	33
Angiotensin‐converting enzyme 2: The old door for new severe acute respiratory syndrome coronavirus 2 infection	33
Anticoagulation outcomes in hospitalized Covid‐19 patients: A systematic review and meta‐analysis of case‐control and cohort studies	32
Inflammatory and vascular biomarkers in post‐COVID‐19 syndrome: A systematic review and meta‐analysis of over 20 biomarkers	32
Mesenchymal stem cells and their derived exosomes to combat Covid–19	31
SARS‐CoV‐2, Covid‐19, and the debunking of conspiracy theories	31
Rhinovirus and asthma: Challenges and opportunities	30
Drugs against SARS‐CoV‐2: What do we know about their mode of action?	29
Impact of breast milk‐acquired cytomegalovirus infection in premature infants: Pathogenesis, prevention, and clinical consequences?	29
Role of p38 mitogen‐activated protein kinase signalling in virus replication and potential for developing broad spectrum antiviral drugs	29
Vaccine‐induced immune thrombotic thrombocytopenia after vaccination against Covid‐19: A clinical dilemma for clinicians and patients	28
Vitamin D supplementation and Covid‐19 outcomes: A systematic review, meta‐analysis and meta‐regression	28
Recent insights into SARS‐CoV‐2 omicron variant	28
Omicron – The new SARS‐CoV‐2 challenge?	27
Epidemiology, prognosis and management of potassium disorders in Covid‐19	27
Population‐based prevalence surveys during the Covid‐19 pandemic: A systematic review	27
Safety and potency of BIV1‐CovIran inactivated vaccine candidate for SARS‐CoV‐2: A preclinical study	26

Efficacy and safety of azithromycin in Covid‐19 patients: A systematic review and meta‐analysis of randomized clinical trials	26
Impact of COVID‐19 on polio vaccination in Pakistan: a concise overview	25
The concept of one health applied to the problem of zoonotic diseases	25
Association of dengue disease severity and blood group: A systematic review and meta‐analysis	25
SARS‐CoV‐2: Mechanism of infection and emerging technologies for future prospects	25
SARS‐CoV‐2 Omicron and its current known unknowns: A narrative review	25
Effect of rotavirus genetic diversity on vaccine impact	24
Lessons from dermatology about inflammatory responses in Covid‐19	24
Lipid‐based therapies against SARS‐CoV‐2 infection	24
ASSURED‐compliant point‐of‐care diagnostics for the detection of human viral infections	23
Comparative effectiveness of N95, surgical or medical, and non‐medical facemasks in protection against respiratory virus infection: A systematic review and network meta‐analysis	23
A systematic review on global RSV genetic data: Identification of knowledge gaps	22
Epidemiology of human adenovirus associated with respiratory infection in southern Brazil	22
Nanobiosensor‐based diagnostic tools in viral infections: Special emphasis on Covid‐19	22
Role of red blood cell distribution width, as a prognostic indicator in COVID‐19: A systematic review and meta‐analysis	22
Reactivation of herpesviruses during COVID‐19: A systematic review and meta‐analysis	22
Reactive oxygen species as potential antiviral targets	22
Monkeypox virus diagnosis and laboratory testing	22
Muscle dysfunction in the long coronavirus disease 2019 syndrome: Pathogenesis and clinical approach	22
Neurological complications associated with Covid‐19; molecular mechanisms and therapeutic approaches	21
Vitamin D and Covid‐19: From potential therapeutic effects to unanswered questions	21
The impact of Parkinson's disease on manifestations and outcomes of Covid‐19 patients: A systematic review and meta‐analysis	21
Remdesivir: A beacon of hope from Ebola virus disease to COVID‐19	21
The effects of orally administered lactoferrin in the prevention and management of viral infections: A systematic review	21
Clotting disorder in severe acute respiratory syndrome coronavirus 2	20
Alternative clinical specimens for the detection of SARS‐CoV‐2: A rapid review	20
Severe acute respiratory syndrome coronavirus‐2 natural animal reservoirs and experimental models: systematic review	20
Prevalence and genotype distribution of human papillomavirus infection in different anatomical sites among men who have sex with men: A systematic review and meta‐analysis	20
Coronavirus disease 2019 (Covid‐19) vaccination recommendations in special populations and patients with existing comorbidities	19
Mega doses of retinol: A possible immunomodulation in Covid‐19 illness in resource‐limited settings	19
Monkeypox: An international epidemic	19
Crosstalk between RNA viruses and DNA sensors: Role of the cGAS‐STING signalling pathway	18
Torque teno virus load as marker of rejection and infection in solid organ transplantation – A systematic review and meta‐analysis	18
Efficacy and safety of sotrovimab in patients with COVID‐19: A rapid review and meta‐analysis	18
Efficacy and safety of tixagevimab‐cilgavimab as pre‐exposure prophylaxis for COVID‐19: A systematic review and meta‐analysis	18
Zoonotic potential of Newcastle disease virus: Old and novel perspectives related to public health	18
The association between dengue viremia kinetics and dengue severity: A systemic review and meta‐analysis	17
Cell death mechanisms involved in cell injury caused by SARS‐CoV‐2	17
Neuropathogenic human coronaviruses: A review	17
Ivermectin and outcomes from Covid‐19 pneumonia: A systematic review and meta‐analysis of randomized clinical trial studies	17
Innate immune evasion mediated by picornaviral 3C protease: Possible lessons for coronaviral 3C‐like protease?	17
Pharmacogenomics of genetic polymorphism within the genes responsible for SARS‐CoV‐2 susceptibility and the drug‐metabolising genes used in treatment	17
Novel coronavirus SARS‐CoV‐2 (Covid‐19) dynamics inside the human body	17
Diverse roles of long non‐coding RNAs in viral diseases	17
Recent developments in SARS‐CoV‐2 vaccines: A systematic review of the current studies	16
The virome in early life and childhood and development of islet autoimmunity and type 1 diabetes: A systematic review and meta‐analysis of observational studies	16
Insight into the role of clathrin‐mediated endocytosis inhibitors in SARS‐CoV‐2 infection	16
Dengue fever and dengue virus in the People's Republic of China	16
EBV associated T‐ and NK‐cell lymphoproliferative diseases: A comprehensive overview of clinical manifestations and novel therapeutic insights	16
Effects of COVID‐19 vaccination during pregnancy on SARS‐CoV‐2 infection and maternal and neonatal outcomes: A systematic review and meta‐analysis	16
Transmission and clearance of human papillomavirus infection in the oral cavity and its role in oropharyngeal carcinoma – A review	15
Insight into the Enterovirus A71: A review	15
Potential COVID‐19 therapeutic approaches targeting angiotensin‐converting enzyme 2; An updated review	15
Clinical manifestations of human Mpox infection: A systematic review and meta‐analysis	15
Effectiveness of public health measures to prevent the transmission of SARS‐CoV‐2 at mass gatherings: A rapid review	15
Prognostic value of novel serum biomarkers, including C‐reactive protein to albumin ratio and fibrinogen to albumin ratio, in COVID‐19 disease: A meta‐analysis	14
Norovirus outbreaks in China, 2000–2018: A systematic review	14
Hospitalised versus outpatient COVID‐19 patients' background characteristics and comorbidities: A systematic review and meta‐analysis	14
Why is temperature sensitivity important for the success of common respiratory viruses?	14
Development of antibody resistance in emerging mutant strains of SARS CoV‐2: Impediment for COVID‐19 vaccines	14
The global emergence of Chikungunya infection: An integrated view	13
Behaviour of aerosols and their role in the transmission of SARS‐CoV‐2; a scoping review	13
Current views on the potentials of convalescent plasma therapy (CPT) as Coronavirus disease 2019 (COVID‐19) treatment: A systematic review and meta‐analysis based on recent studies and previous respir	13
SARS‐CoV‐2 and dengue virus co‐infection: Epidemiology, pathogenesis, diagnosis, treatment, and management	13
Evidence for altered host genetic factors in KSHV infection and KSHV‐related disease development	13
Intravenous immunoglobulin (IVIg) therapy in hospitalised adult COVID‐19 patients: A systematic review and meta‐analysis	13
Prevalence of oral manifestations in COVID‐19: A systematic review	13
Quercetin for the treatment of COVID‐19 patients: A systematic review and meta‐analysis	13
Regulation of autophagy by high‐ and low‐risk human papillomaviruses	13
Clinical performance of rapid antigen tests in comparison to RT‐PCR for SARS‐COV‐2 diagnosis in Omicron variant: A systematic review and meta‐analysis	13
Long noncoding RNAs in respiratory viruses: A review	12
Effect of corticosteroid therapy on mortality in COVID‐19 patients—A systematic review and meta‐analysis	12
Persistence of humoral response upon SARS‐CoV‐2 infection	12
The prevalence, predictors and outcomes of acute liver injury among patients with COVID‐19: A systematic review and meta‐analysis	12
Current pharmacological modalities for management of novel coronavirus disease 2019 (COVID‐19) and the rationale for their utilization: A review	12
Model systems for studying extrahepatic pathogenesis of hepatitis E virus. Current knowledge and future directions	12
The role of human papillomavirus in the pathogenesis of sinonasal inverted papilloma: a narrative review	12
Isothermal amplification‐based assays for rapid and sensitive detection of severe acute respiratory syndrome coronavirus 2: Opportunities and recent developments	12
Systematic review of the efficacy, effectiveness and safety of high‐dose seasonal influenza vaccines for the prevention of laboratory‐confirmed influenza in individuals ≥18 years of age	12
Clinical and laboratory factors associated with coronavirus disease 2019 (Covid‐19): A systematic review and meta‐analysis	12

Does bacillus Calmette‐Guérin vaccine prevent herpes simplex virus recurrences? A systematic review	12
The Suppressor of Cytokine Signalling family of proteins and their potential impact on COVID‐19 disease progression	12
Systematic review of host genetic association with Covid‐19 prognosis and susceptibility: What have we learned in 2020?	12
Enteroviruses in gastrointestinal diseases	11
Passive immunotherapies for COVID‐19: The subtle line between standard and hyperimmune immunoglobulins is getting invisible	11
The association of human leucocyte antigen (HLA) alleles with COVID‐19 severity: A systematic review and meta‐analysis	11
The relationship between blood groups and risk of infection with SARS‐CoV‐2 or development of severe outcomes: A review	11
The innate immune response in Zika virus infection	11
HTLV‐1 oncovirus‐host interactions: From entry to the manifestation of associated diseases	11
Type B coxsackieviruses and central nervous system disorders: critical review of reported associations	11
Aedes mosquitoes in the emerging threat of urban yellow fever transmission	11
Association of adenovirus 36 infection and obesity; An updated meta‐analysis of community‐based studies	11
A rapid review of measures to support people in isolation or quarantine during the Covid‐19 pandemic and the effectiveness of such measures	10
Temperature dependent viral tropism: understanding viral seasonality and pathogenicity as applied to the avoidance and treatment of endemic viral respiratory illnesses	10
Antioxidant/anti‐inflammatory effect of Mg²⁺ in coronavirus disease 2019 (COVID‐19)	10
Interindividual immunogenic variants: Susceptibility to coronavirus, respiratory syncytial virus and influenza virus	10
Combating coxsackievirus B infections	10
The expanding arms of Zika virus: An updated review with recent Indian outbreaks	10
Does enterovirus 71 urge for effective vaccine control strategies? Challenges and current opinion	10
Safety and immunogenicity of Zika virus vaccine: A systematic review of clinical trials	10
Effect of prior immunisation with smallpox vaccine for protection against human Mpox: A systematic review	10
Detection of respiratory viruses directly from clinical samples using next‐generation sequencing: A literature review of recent advances and potential for routine clinical use	10
The effectiveness of non‐contact thermal screening as a means of identifying cases of Covid‐19: a rapid review of the evidence	10
Worldwide prevalence of human papillomavirus among pregnant women: A systematic review and meta‐analysis	10
Transplantation in the era of the Covid‐19 pandemic: How should transplant patients and programs be handled?	9
HIV‐1 viral load testing in resource‐limited settings: Challenges and solutions for specimen integrity	9
A review on disease burden and epidemiology of childhood parainfluenza virus infections in Asian countries	9
Does dengue and COVID‐19 co‐infection have worse outcomes? A systematic review of current evidence	9
Coronavirus disease‐19 and cardiovascular disease: A risk factor or a risk marker?	9
Review of studies of severe acute respiratory syndrome related coronavirus–2 pathogenesis in human organoid models	9
Systematic review of the efficacy, effectiveness and safety of cell‐based seasonal influenza vaccines for the prevention of laboratory‐confirmed influenza in individuals ≥18 years of age	9
Insights on Mpox virus infection immunopathogenesis	9
Antivirals against human polyomaviruses: Leaving no stone unturned	9
SARS‐CoV‐2‐related and Covid‐19 vaccine‐induced thromboembolic events: A comparative review	8
Human brain organoids to explore SARS‐CoV‐2‐induced effects on the central nervous system	8
Assessing severe acute respiratory syndrome coronavirus 2 infectivity by reverse‐transcription polymerase chain reaction: A systematic review and meta‐analysis	8
Intricate interplay between Covid‐19 and cardiovascular diseases	8
Redox‐sensitive signalling pathways regulated by human papillomavirus in HPV‐related cancers	8
Features of HLA class I expression and its clinical relevance in SARS‐CoV‐2: What do we know so far?	8
COVID‐19 susceptibility and clinical outcomes in inflammatory bowel disease: An updated systematic review and meta‐analysis	8
Tick‐borne encephalitis: A comprehensive review of the epidemiology, virology, and clinical picture	8
Effectiveness of rapid antigen testing for screening of asymptomatic individuals to limit the transmission of SARS‐CoV‐2: A rapid review	8
Background to new treatments for COVID‐19, including its chronicity, through altering elements of the cytokine storm	7
Severe acute respiratory syndrome‐coronavirus‐2: Current advances in therapeutic targets and drug development	7
Human pegivirus type 1 infection in Asia—A review of the literature	7
The role of IL‐1β during human immunodeficiency virus type 1 infection	7
Systematic review of the efficacy, effectiveness and safety of recombinant haemagglutinin seasonal influenza vaccines for the prevention of laboratory‐confirmed influenza in individuals ≥18 years of a	7
Global molecular prevalence and genotype distribution of Sapovirus in children with gastrointestinal complications: A systematic review and meta‐analysis	7
The role of cytokines and their antagonists in the treatment of COVID‐19 patients	7
Systematic review of the efficacy, effectiveness and safety of MF59^® adjuvanted seasonal influenza vaccines for the prevention of laboratory‐confirmed influenza in individuals ≥18 years of	7
SARS‐CoV‐2 nucleocapsid: Biological functions and implication for disease diagnosis and vaccine design	7
Metabolic reprogramming and immune regulation in viral diseases	7
An annoying enteric virus: A systematic review and meta‐analysis of human astroviruses and gastrointestinal complications in children	7
Hydroxychloroquine in the treatment of coronavirus disease 2019: Rapid updated systematic review and meta‐analysis	7
Cardiac manifestations in children with the multisystem inflammatory syndrome (MIS‐C) associated with SARS‐CoV‐2 infection: Systematic review and meta‐analysis	7
Tocilizumab in COVID‐19 pneumonia: Practical proposals based on a narrative review of randomised trials	7
Host factors associated with either VP16 or VP16‐induced complex differentially affect HSV‐1 lytic infection	6
Emergence of novel coronavirus and progress toward treatment and vaccine	6
Hepatitis B virus pre‐S region: Clinical implications and applications	6
Testosterone and Covid‐19: An update	6
Viruses of the oral cavity: Prevalence, pathobiology and association with oral diseases	6
Biomarkers of endothelial dysfunction are associated with poor outcome in COVID‐19 patients: A systematic review and meta‐analysis	6
Epitope mapping of neutralising anti‐SARS‐CoV‐2 monoclonal antibodies: Implications for immunotherapy and vaccine design	6
CAR T cells: Living HIV drugs	6
Indirect effects of cytomegalovirus infection: Implications for vaccine development	6
Hepatitis B virus core‐related antigen (HBcrAg) as a prognostic marker for the development of hepatocellular carcinoma: A mini systematic review of the literature	6
Anakinra was not associated with lower mortality in hospitalised COVID‐19 patients: A systematic review and meta‐analysis of randomized controlled trials	6
Efficacy of tocilizumab in the treatment of COVID‐19: An umbrella review	6
Therapeutic roles of CAR T cells in infectious diseases: Clinical lessons learnt from cancer	6
Ethnicity as a risk factor for vitamin D deficiency and undesirable COVID‐19 outcomes	6
How strong is the evidence that it is possible to get SARS‐CoV‐2 twice? A systematic review	6
Crosstalk between estrogen, dendritic cells, and SARS‐CoV‐2 infection	6
Risk profile and mode of transmission of Mpox: A rapid review and individual patient data meta‐analysis of case studies	6